OUR SINCERE APPRECIATION TO

SUZHOU INDUSTRIAL PARK ADMINISTRATIVE COMMITTEE COLD SPRING HARBOR ASIA CSHA CEO’S REPORT 冷泉港亚洲 冷泉港亚洲首席执行官报告

2013 CSHA President’s Essay Plan the timing and pace of your talk, or the layout of your poster, 2013 Summary mission is that our CSHA program, while headquartered in Suzhou, with care. Good organization really helps in navigating through should reach out as broadly as possible to bene t life scientists even complex material, and will make your science stand out throughout the entire Asia-Paci c region. Excitingly, 2013 marked the Stories can be told in many ways. Good 2013 was a year of increased momentum compared to your competition. Even negative or mixed results rst extension of activities outside China. In collaboration with the scienti c stories usually follow a narrative in investment in scienti c research and can be presented in such a way as to drive the narrative forward. Japanese Biochemistry Society (JBS) we hosted an independent form typical of a well-rounded tale, with a education by governments in the In terms of timing of your presentation, running over by a minute session at JBS’s 86th annual meeting in Yokohama. This CSHA beginning, in which the scope of the plot Asia-Paci c region. In response to this or so is generally accepted, but better still prepare to nish within session in Japan addressed the latest developments in epigenetics, unfolds, a middle, in which the narration robust growth in funding, more the allotted time. It is rude to take time away from other involved an outstanding cast of international scientists from Singapore, twists and turns, and an end, when all is well-trained scientists are migrating or presenters, either because you think your work is so important or Korea, USA, China and Japan, and embodied the same scienti c spirit revealed. Narrating the story of your returning to Asia; there is a real sense of because you did not plan well. Too many times, I have witnessed and open discussion as our meetings in Suzhou and Cold Spring scienti c discovery through a scienti c optimism and con dence in the air. The a presenter antagonize an audience by not nishing on time, and Harbor. talk or poster requires care and thought, scienti c landscape of the Asia-Paci c all that anyone can remember afterwards is that the person a good understanding of your audience, region is rapidly being transformed, and the impact is overran their time, not the work they presented. Indeed 2013 was a remarkable year for Cold Spring Harbor Asia. a clear grasp of the logical ow of your material, all best being felt around the world. These positive factors leavened with a little humor. continue to reshape and increase research productivity in Design your slides or poster to be legible and clear by the entire the region, best exempli ed by the exponential growth of audience, not just the big shots in the front row, without excess Cold Spring Harbor meetings are famous for the large publications in internationally accredited journals. Echoing use of transitions or animations, except when these help in number of short talks selected from the openly submitted this trend, CSHA worked hard in 2013 to capture a wider conveying a scienti c point. Only include data or concepts that abstracts, many given by rst-time presenters. The range of rapid scienti c developments in the life sciences. you are going to have time to address in your presentation. Large opportunity to learn the latest unpublished work is as The new meetings we developed this year, for example on amounts of data on slides that you have no time to cover is much part of the rationale in attending our meetings as is metabolism, membrane proteins, infectious diseases and confusing, and detracts from your narrative. the chance to mix with leading experts. And whether you host interactions, epitomize CSHA’s efforts to broaden are offered the opportunity of a keynote talk, a ten minute our program and showcase much new and vital research Acknowledge the work of others as you go along. Many of your short talk or a poster, many of the same rules apply to from around the region. preparing your material. Plan your presentation with care, colleagues and collaborators may be in the audience, and they will not appreciate having their contributions unrecognized. You out of respect for those to whom you will be telling your For us, 2013 not only saw a steady growth in the number can do this throughout the presentation or at the end, but do not story. All the more reason to do this, since CSHA of our meetings, but was also a year in which the quality of forget to reference the work of others whenever it is appropriate. audiences are international, with many having travelled a our conferences went from strength to strength. Among It can lend heft to your own research and shows that you are able very long way to hear you. Here are a number of points to the highlights of 2013, the CSHA optical imaging meeting to integrate your work in a broader context. And when handling consider: has evolved into one of the CSHA’s signature meetings the discussion after your talk, avoid condescending or patronizing and is now a key event in this particular eld: the list of the the person asking the question-sometimes it can help to rephrase Firstly, know your audience. This should inform the extent speakers now include the premier key players actively their question out loud, in case it was missed by some of the of introductory material needed and should dictate how working at the cutting-edge of molecular and cellular audience rst time round. much jargon you can use (the less the better!). A broader imaging. While all our meetings attract signi cant numbers audience needs more context of why your work is of distinguished and established scientists as speakers, in In summary, my general advice to would-be presenters is that important, and how it ts into the wider picture. A highly many ways the real highlights of each program are the practice makes perfect. Know your slides, practice by presenting specialized audience may need at most one introductory outstanding short talks given by promising junior scientists the talk or poster out loud to peers, practice at home and practice slide or gure, before you go into the details of your from key labs around the Asia-Paci c region. research. At all times, try to keep your audience engaged, on your way to the conference. That will ensure you get your message across, and can lead to useful discussion, even when you are in front of hundreds of people, through Deeply ingrained into Cold Spring Harbor Laboratory’s eye contact, pacing and style. collaborations or even job offers!

Don’t overwhelm your audience with too much content. However much work you and your labmates may have done, think carefully about how much material you can present in the allotted time. Make sure you leave enough time for your novel and unpublished work to be showcased, since what you are looking for is feedback and comment on work you plan to publish, not what is already in the public domain.

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MECHANISMS AND FUNCTIONS OF NON-APOPTOTIC CELL DEATH 非凋亡性细胞死亡的机制和功能

April 15-19 148 Participants

ORGANIZED BY Junying Yuan, Harvard Medical School, USA 美国哈佛大学医学院 Jiahuai Han, Xiamen University, CHINA 中国厦门大学 Masayuki Miura, University of Tokyo, JAPAN 日本东京大学 Peter Vandenabeele, Ghent University, VIB, BELGIUM 比利时根特大学 KEYNOTE SPEAKER Shigekazu Nagata, Kyoto University, Graduate School of Medicine, JAPAN 日本京都大学医学研究生院 PROGRAM SIGNAL TRANSDUCTION OF NECROPTOSIS I INVITED SPEAKERS Jiahuai Han, Xiamen University, CHINA Avi Ashkenazi, Genentech, Inc., USA 美国基因工程技术公司 Eric Baehrecke, University of Massachusetts Medical School, USA 美国麻省大学医学院 Alexei Degterev, Tufts University, USA 美国塔夫斯大学 PATHOLOGICAL ROLES OF NECROPTOSIS Douglas Green, St. Jude Children's Research Hospital, USA 美国圣裘德儿童研究医院 Peter Vandenabeele, Ghent University, VIB, BELGIUM William Kaiser, Emory University, USA 美国埃默里大学 Sharad Kumar, Centre for Cancer Biology, AUSTRALIA 澳大利亚肿瘤生物学中心 NON-APOPTOTIC CELL DEATH AND HOST DEFENSE RESPONSE Masayuki Miura, University of Tokyo, JAPAN 东京大学 Francis Chan, University of Massachusetts Medical School, USA Zheng-Hong Qin, Soochow University School of Pharmaceutical Science, CHINA 中国苏州大学药学院 Shai Shaham, The Rockefeller University, USA 美国洛克菲勒大学 FROM APOPTOSIS TO NON-APOPTOSIS Yigong Shi, Tsinghua University, CHINA 中国清华大学 Shigeomi Shimizu, Tokyo Medical and Dental University, JAPAN 东京医科歯科大学 Adrian T. Ting, Mount Sinai School of Medicine, USA Brent Stockwell, HHMI/ Columbia University, USA 美国霍华德休斯医学研究院/ 美国哥伦比亚大学 Nektarios Tavernarakis, Foundation for Research and Technology-Hellas, GREECE 希腊研究与技术基金会 MULTIPLE TYPES OF NON-APOPTOTIC CELL DEATH Adrian Ting, Mount Sinai School of Medicine, USA 美国纽约西奈山研究院 Zheng-Hong Qin, Soochow University School of Pharmaceutical Science, CHINA Henning Walczak, Imperial College London, UK 英国帝国理工学院 David Wallach, Weizmann Institute of Science, ISRAEL 以色列魏兹曼科学研究所 NON-APOPTOTIC CELL DEATH IN DIFFERENT ORGANISMS Xiaodong Wang, National Institute of Biological Sciences, CHINA 北京生命科学研究所 Masayuki Miura, University of Tokyo, JAPAN Hao Wu, Boston Children's Hospital, Harvard Medical School, USA 美国波士顿儿童医院/ 美国哈佛大学医学院 Sandra Zinkel, Vanderbilt University School of Medicine, USA 美国范德堡大学医学院

5 6 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

FRANCIS CRICK SYMPOSIUM ON NEUROSCIENCE: THE CHANGING BRAIN KEYNOTE SPEAKER 弗朗西斯 · 克里克神经科学论坛：不断变化的大脑 Atsushi Miyawaki, Riken Brain Science Institute, JAPAN 日本理化学研究脑科学研究所 INVITED SPEAKERS Richard Benton, University of Lausanne, SWITZERLAND 瑞士洛桑大学 May 6 - 10 258 Participants Guo-Qiang Bi, University of Science and Technology of China, CHINA 中国科技大学 Tobias Bonhoeffer, Max-Planck-Institute of Neurobiology, GERMANY 德国马克斯·普朗克科学促进协会 Xiaoke Chen, Stanford University, USA 美国斯坦福大学 Yang Dan, University of California, Berkeley, USA 美国加州大学伯克利分校 Kenji Doya, Okinawa Institute of Science and Technology, JAPAN 日本冲縄科学技术大学院大学 ORGANIZED BY Marla Feller, University of California, Berkeley, USA 美国加州大学伯克利分校 Nancy Ip, The Hong Kong University of Science and Technology, CHINA Guoping Feng, McGovern Institute for Brain Research at MIT, USA 美国麻省理工学院麦戈文研究所 香港科技大学 Anirvan Ghosh, F. Hoffmann-La Roche, SWITZERLAND 瑞士巴塞尔豪夫迈.罗氏有限公司 Liqun Luo, Stanford University, USA 美国斯坦福大学 Hailan Hu, Shanghai Institutes for Biological Sciences, China 中国上海生命科学院 Karel Svoboda, HHMI, Janelia Farm Research Campus, USA Yuh-Nung Jan, University of California, San Francisco/ HHMI, USA 美国加州大学洛杉矶分校/ 美国霍华德休斯医学研究所 美国霍华德休斯医学研究所珍妮莉娅法姆研究学院 Na Ji, Janelia Farm Research Campus/ HHMI, USA 美国霍华德休斯医学研究所珍妮莉娅法姆研究学院 Arnold Kriegstein, University of California at San Francisco, USA 美国加州大学洛杉矶分校 Virginia Lee, University of Pennsylvania School of Medicine, USA 美国宾夕法尼亚大学医学院 PROGRAM Liqun Luo, Stanford University, USA 美国斯坦福大学 NEW TECHNOLOGY Minmin Luo, National Institute of Biological Sciences, Beijing, CHINA 中国北京生命科学研究所 K. Svoboda, HHMI Janelia Farm Research Campus, Ashburn, Virginia, USA Christian Lüscher, University of Geneva, SWITZERLAND 瑞士日内瓦大学 Judit Makara, Institute of Experimental Medicine, HUNGARY 匈牙利科学院实验医学研究所 THE DEVELOPING BRAIN Robert Malenka, Stanford University School of Medicine, USA 美国斯坦福大学医学院 Adi Mizrahi, The Hebrew University of Jerusalem, ISRAEL 以色列耶路撒冷希伯莱大学 L. Luo, Stanford University, California, USA Hitoshi Okamoto, RIKEN Brain Science Institute, JAPAN 日本脑科学研究所 Mu-Ming Poo, University of California, Berkeley, USA 美国加州大学伯克利分校 THE PLASTIC BRAIN I Bernardo Sabatini, Harvard Medical School, USA 美国哈佛大学医学院 N. Ip, The Hong Kong University of Science and Technology, CHINA Hitoshi Sakano, The University of Tokyo, JAPAN 日本东京大学 Song-Hai Shi, MSKCC, USA 美国纪念斯隆-凯特琳癌症中心 THE PLASTIC BRAIN II Nelson Spruston, HHMI Janelia Farm Research Campus, USA 美国霍华德休斯医学研究所珍妮莉娅法姆研究学院 H. Hu, Shanghai Institutes for Biological Sciences, Shanghai, CHINA Scott Sternson, Janelia Farm Research Campus, HHMI, USA 美国霍华德休斯医学研究所珍妮莉娅法姆研究学院 Thomas Sudhof, Stanford University School of Medicine/ HHMI, USA 美国斯坦福大学医学院/ 美国霍华德休斯医学研究院 Michael Sutton, University of Michigan, USA 美国密歇根大学 THE DYNAMIC BRAIN Susumu Tomita, Yale University School of Medicine, USA 美国耶鲁大学医学院 Y. Zuo, University of California, Santa Cruz, USA Li-Huei Tsai, Massachusetts Institute of Technology/ HHMI, USA 美国麻省理工学院/ 美国霍华德休斯医学研究院 Naoshige Uchida, Harvard University, USA 美国哈佛大学 THE DISEASE BRAIN Mehmet Yanik, Massachusetts Institute of Technology, USA 美国麻省理工学院 N. Ip, The Hong Kong University of Science and Technology, CHINA Fengwei Yu, Temasek Life Sciences Laboratory, SINGAPORE 新加坡淡马锡生命科学院 Karen Zito, University of California Davis, USA 美国加州大学戴维斯分校 Yi Zuo, University of California Santa Cruz, USA 美国加州大学圣克鲁兹分校 THE EVOLVING BRAIN L. Luo, Stanford University, California, USA

BRAIN CIRCUITS IN ACTION K. Svoboda, HHMI Janelia Farm Research Campus, Ashburn, Virginia, USA

7 8 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

MEMBRANE PROTEIN STRUCTURE AND FUNCTION KEYNOTE SPEAKERS Reinhard Jahn, Max Planck Institute for Biophysical Chemistry, GERMANY 膜蛋白：结构与功能 德国马克斯普朗克生物物理化学研究所 Tom Rapoport, HHMI/ Harvard Medical School, USA 国霍华德休斯医学研究所/ 美国哈佛医学院 May 13-17 162Participants Yigong Shi, Tsinghua University, CHINA 中国清华大学 INVITED SPEAKERS James Chou, Harvard Medical School, USA 美国哈佛医学院 Liang Feng, Stanford University, USA 美国斯坦福大学 Matthew Freeman, MRC Laboratory of Molecular Biology, UNITED KINGDOM 英国剑桥分子生物学实验室 Sebastien Granier, Stanford University, USA 美国斯坦福大学 Carola Hunte, University of Freiburg, GERMANY 德国弗莱堡大学 Jim Hurley, NIH, USA 美国国立卫生研究院 Youxing Jiang, HHMI/ The University of Texas Southwestern Medical Center at Dallas, USA 美国霍华德休斯医学研究所/ 美国德州大学达拉斯西南医学中心 Ronald Kaback, University of California, Los Angeles, USA 美国加州大学洛杉矶分校 Michael Kozlov, Tel Aviv University, ISRAEL 以色列特拉维夫大学 Martin Lohse, University of Wurzburg, GERMANY 德国伍兹堡大学 Hassane Mchaourab, Vanderbilt University, USA 美国范德堡大学 Thomas Meier, Max Planck Institute of Biophysics, GERMANY 马克斯普朗克生物物理研究所 Robert Nakamoto, University of Virginia, USA 美国弗吉尼亚大学 Eduardo Perozo, the University of Chicago, USA 美国芝加哥大学 Carol Robinson, University of Oxford, UNITED KINGDOM 英国牛津大学 Hazime Saito, Himeji Institute of Technology, JAPAN 日本姬路工业大学 Georgios Skiniotis, University of Michigan, USA 美国密歇根大学 Ja Steyaert, Vrije Universiteit Brussel & Vlaams Instituut Biotechnologie, BELGIUM ORGANIZED BY Sinisa Urban, HHMI/ Johns Hopkins University, USA 约翰霍普金斯大学 Carola Hunte, University of Freiburg, GERMANY 德国弗莱堡大学 Michael Wolfe, Harvard Medical School, USA 美国哈佛医学院 Brian Kobilka, Stanford University, USA 美国斯坦福大学 Chenqi Xu, Chinese Academy of Sciences, CHINA 中国清华大学 Robert Nakamoto, University of Virginia, USA 美国弗吉尼亚大学 Nieng Yan, Tsinghua University, CHINA 中国清华大学 Nieng Yan, Tsinghua University, CHINA 中国清华大学 Maojun Yang, Tsinghua University, CHINA 中国清华大学 Peng Zhang, Shanghai Institutes for Biological Sciences, CAS, CHINA 中国科学院上海生命研究院 PROGRAM Ming Zhou, Baylor College of Medicine, USA 美国贝勒医学院 MEMBRANE RECEPTORS I C. Hunte, University of Freiburg, Freiburg, GERMANY

MEMBRANE RECEPTORS II MEMBRANE SHAPING EMERGING TECHNOLOGIES MEMBRANE COMPLEXES CHANNELS AND TRANSMEMBRANE SENSING MEMBRANE ENYMES TRANSPORTERS

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METABOLISM, OBESITY AND OBESITY-ASSOCIATED DISEASES KEYNOTE SPEAKERS Robert V. Farese, University of California, San Francisco, USA 美国加州大学洛杉矶分校 代谢、肥胖及肥胖相关疾病 Takashi Kadowaki, University of Tokyo, JAPAN 日本东京大学

INVITED SPEAKERS May 20-24 142Participants Morris Birnbaum, University of Pennsylvania, USA 美国宾夕法尼亚大学 Barbara Cannon, Stockholm University, SWEDEN 瑞典斯德哥尔摩大学 T.Y. Chang, Dartmouth Medical School, USA 美国达特茅斯医学院 Russell DeBose-Boyd, UT Southwestern Medical Center, USA 美国德州大学西南医学中心 Gen-Sheng Feng, UCSD School of Medicine, USA 美国加州大学圣地亚哥分校医学院 ORGANIZED BY Ira Goldberg, Columbia University, USA 美国哥伦比亚大学 Morris J. Birnbaum, University of Pennsylvania, USA 美国宾夕法尼亚大学 David James, Garvan Institute of Medical Research, AUSTRALIA 澳大利亚医学研究所 David James, Garvan Institute of Medical Research, AUSTRALIA 澳大利亚加尔文医学研究所 Jae Bum Kim, Seoul National University, KOREA 韩国首尔大学 Karen Reue, University of California, Los Angeles, USA 美国加州大学洛杉矶分校 Peng Li, Tsinghua University, CHINA 中国清华大学 Bao-Liang Song, Shanghai Institutes for Biological Sciences, CAS, CHINA 中国科学院上海生命科学研究院 Jiandie Lin, University of Michigan, USA 美国密歇根大学 Frederick Max eld, Weill Cornell Medical College, USA 美国康奈尔大学医学院 PROGRAM Jan Nedergaard, Stockholm University SWEDEN 瑞典斯德哥尔摩大学 ENERGY HOMEOSTASIS Darrell Neufer, East Carolina University, USA 美国东卡罗莱纳大学 Jeffrey Pessin, Albert Einstein College of Medicine, USA 美国艾伯特爱因斯坦医学院 J. Nedergaard, Stockholm University, Stockholm, SWEDEN Karen Reue, University of California, Los Angeles, USA 美国加州大学洛杉矶分校 J. Lin, University of Michigan, Ann Arbor, Michigan, USA Kei Sakamoto, Nestlé Institute of Health Sciences, SWITZERLAND 瑞士雀巢健康科学研究所 M. Celeste Simon, HHMI/ University of Pennsylvania, USA 美国霍华德休斯医学研究院/美国宾夕法尼亚大学 LIPOTOXICITY Stephen Simpson, The University of Sydney, AUSTRALIA 澳大利亚悉尼大学 K. Reue, University of California-Los Angeles, Los Angeles, California, USA Bao-Liang Song, Shanghai Institutes for Biological Sciences, CAS, CHINA 中国科学院上海生命科学研究院 J.B. Kim, Seoul National University, Seoul, KOREA Cheryl Wellington, University of British Columbia, CANADA 加拿大英属哥伦比亚大学 Hongyuan) Rob Yang, University of New South Wales, AUSTRALIA 澳大利亚新南威尔士大学 INSULIN SIGNALING AND INSULIN RESISTANCE Shimin Zhao, Fudan University, CHINA 中国复旦大学 D. James, Garvan Institute of Medical Research, Darlinghurst, AUSTRALIA M. Birnbaum, University of Pennsylvania, Philadelphia, Pennsylvania, USA

INTRACELLULAR STRESS IN OBESITY AND DIABETES AND INFLAMMATION H.F. Gu, Karolinska University Hospital, Stockholm, SWEDEN H. Yang, University of New South Wales, Sydney, AUSTRALIA

ADIPOCYTES, LIPID DROPLETS AND LIPOLYSIS P. Li, Tsinghua University, Beijing, CHINA G.-S. Feng, University of California-San Diego, La Jolla, California, USA

CHOLESTEROL, HEART AND ATHEROSCLEROSIS F. Max eld, Weill Cornell Medical College, New York, New York, USA R. DeBose-Boyd, HHMI/ UT Southwestern Medical Center, Dallas, Texas, USA

METABOLISM, NEUROLOGICAL DISORDERS AND OTHERS C. Wellington, University of British Columbia, Vancouver, CANADA I. Goldberg, Columbia University, New York, New York, USA

11 12 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

VACCINE DESIGN 疫苗设计

June 3 -7 69 Participants

ORGANIZED BY Michael Good, Grif th University, AUSTRALIA 澳大利亚格里菲斯大学 Yiming Shao, Chinese Center for Disease Control and Prevention, CHINA 中国疾病预防控制中心 Linqi Zhang, Tsinghua University, China 中国清华大学

PROGRAM VACCINE TECHNOLOGY I KEYNOTE SPEAKERS M. Good, Grif th University, Southport, AUSTRALIA Dennis Burton, The Scripps Research Institute, USA 美国斯克里普斯研究所 S. Lu, University of Massachusetts Medical Center, Worcester, USA David Ho, Aaron Diamond AIDS Res Center, USA 美国亚伦·戴蒙德艾滋病研究中心

VACCINE DESIGN I INVITED SPEAKERS Y. Shao, Chinese Center for Disease Control and Prevention, Beijing, CHINA Gabrielle Belz, Walter and Eliza Hall Institute of Medical Research, AUSTRALIA 澳大利沃尔特伊丽莎医学研究所 Luigi Buonaguro, National Cancer Institute, Naples, ITALY 意大利国家癌症研究所 HIV VACCINE AND IMMUNOLOGY Michael Good, Grif th University, AUSTRALIA 澳大利亚格里菲斯大学 Ken Ishii, National Institute of Biomedical Innovation(NIBIO), Immunology Frontier Research Center (IFREC), Osaka University, JAPAN J. McElrath, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA 日本国家生物医学创新研究所/ 日本免疫学前沿研究中心/ 日本大阪大学 R. Wyatt, The Scripps Research Institute, La Jolla, California, USA Rajiv Khanna, Queensland Institute of Medical Research, AUSTRALIA 澳大利亚昆士兰医学研究所 David Klatzmann, UMR 7211 UPMC/ CNRS, Pierre & Marie Curie University, FRANCE VACCINE TOWARDS BACTERIA AND CANCER Mi-Na Kweon, International Vaccine Institute, KOREA 韩国国际疫苗研究所 T. Lehner, King’s College London, UNITED KINGDOM Thomas Lehner, Kings College London, UNITED KINGDOM 英国伦敦大学国王学院 Larry (Huaxin) Liao, Duke University Medical Center, USA 美国杜克大学医学院 VACCINE DESIGN II Shan Lu, University of Massachusetts Medical Center, USA 美国麻省大学医学院 R. Khanna, Queensland Institute of Medical Research, AUSTRALIA M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA 美国弗莱德-哈钦森癌症研究中心 James Mullins, University of Washington, USA 美国华盛顿大学 David Pascual, Montana State University, USA 美国蒙大拿州立大学 VIRAL IMMUNOLOGY Ruth Ruprecht, Dana-Farber Cancer Institute, USA 美国丹纳-法伯癌症研究所 R. Ruprecht, Dana-Farber Cancer Institute, Boston, Massachusetts, USA Yiming Shao, Chinese Center for Disease Control and Prevention, CHINA 中国疾病预防控制中心 Zhong Su, Guangzhou Institutes of Biomedicine and Health, CHINA 中国科学院广州生物医药与健康研究院 VACCINE TECHNOLOGY II Richard Wyatt, The Scripps Research Institute, USA 美国斯克里普斯研究所 S. Goodswen, University of Technology Sydney, AUSTRALIA Cassian Yee, University of Washington, USA 美国华盛顿大学 L. Chen, Guangzhou Institute of Biomedicine and Health, CHINA Linqi Zhang, Tsinghua University, CHINA 中国清华大学 Tongqing Zhou, Vaccine Research Center, NIAID/ NIH, USA 美国国立卫生研究院/ 美国过敏和传染病研究所, 疫苗研究中心 FUTURE VACCINES Jiang Zhu, NIH/ NIAID, USA 美国国立卫生研究院/ 美国过敏和传染病研究所 M. Good, Grif th University, Southport, AUSTRALIA L. Zhang, Tsinghua University, CHINA

13 14 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

PLANT CELL AND DEVELOPMENTAL BIOLOGY KEYNOTE SPEAKERS Jiayang Li, Institute of Genetics and Developmental Biology, CHINA 中国科学院遗传与发育生物研究所 植物细胞和发育生物学 Natasha Raikhel, University of California, Riverside, USA 美国加州大学河滨分校

INVITED SPEAKERS June 17-21 132 Participants Frederic Berger, Temasek Life Sciences Laboratory, National University of Singapore, SINGAPORE 新加坡淡马锡生命科学院/ 新加坡国立大学 David Bouchez, Institut Jean-Pierre Bourgin, FRANCE Xiaoya Chen, Shanghai Institutes of Biological Sciences, CHINA 中国上海生命研究院 Zhixiang Chen, Purdue University, USA 美国普渡大学 ORGANIZED BY Juan Dong, Waksman Institute, USA 美国Waksman研究所 Tetsuya Higashiyama, Nagoya University, JAPAN 日本名古屋大学 Pankaj Dhonukshe, VIB/ Universiteit Gent, BELGIUM 比利时VIB研究所/ 比利时根特大学 Bo Liu, University of California, Davis, USA 美国加州大学达文斯分校 Thomas Dresselhaus, University of Regensburg, GERMANY 德国雷根斯堡大学 Hong Ma, Fudan University/ Pen State University, CHINA/ USA Hiroo Fukuda, University of Tokyo, JAPAN 日本东京大学 中国复旦大学/ 美国宾州州立大学 Niko Geldner, University of Lausanne, SWITZERLAND 瑞士洛桑大学 Zhenbiao Yang, University of California Riverside, USA Venugopala Gonehal, University of California, Riverside, USA 美国加州大学河滨分校 美国加州大学河滨分校 John Harada, University of California, Davis, USA 美国加州大学达文斯分校 Takashi Hashimoto, Nara Institute of Sceince and Technology, JAPAN 日本奈良先端技术大学院大学 PROGRAM Tetsuya Higashiyama, Nagoya University, JAPAN 日本名古屋大学 TRAFFICKING Inhwan Hwang, Pohang University of Science & Technology, KOREA 韩国浦项科技大学 Liwen Jiang, The Chinese University of Hong Kong, CHINA 香港中文大学 L. Jiang, Chinese University of Hong Kong, Hong Kong, CHINA Jürgen Kleine-Vehn, Universität für Bodenkultur Wien (BOKU), AUSTRIA 奥地利维也纳农业大学 Thomas Laux, University of Freiburg, GERMANY 德国弗莱堡大学 Bo Liu, University of California, Davis, USA 美国加州大学达文斯分校 CELLULAR SIGNALING Jianxiang Liu, Fudan University, CHINA 中国复旦大学 J. Sheen, Massachusetts General Hospital, Boston, Massachusetts, USA Hong Ma, Fudan University/ Pen State University, CHINA/ USA 中国复旦大学/ 美国宾州大学 Li-Jia Qu, Peking University, CHINA 中国北京大学 Mengxiang Sun, Wuhan University, Wuhan, CHINA 中国武汉大学 CYTOSKELETON I Jen Sheen, MGH/ Harvard Medical School, USA 美国马里昂总医院/ 哈佛大学医学院 B. Liu, University of California, Davis, California, USA Keiko Torii, University of Washington, USA 美国华盛顿大学 Tongda Xu, Temasek Lifescience Laboratory, SINGAPORE 淡马锡生命科学研究院 CYTOSKELETON II Zhenbiao Yang, University of California Riverside, USA 美国加州大学河滨分校 T. Hashimoto, Nara Institute of Science and Technology, Ikoma, JAPAN

CELL POLARITY AND FATE DETERMINATION X.-Y. Chen, Shanghai Institute of Plant Physiology and Ecology, Shanghai, CHINA

CELL DIVISION AND DEVELOPMENT H. Fukuda, University of Tokyo, Tokyo, JAPAN

STEM CELLS AND EMBRYOGENESIS T. Laux, Albert-Ludwigs-University Freiburg, Freiburg, GERMANY

REPRODUCTIVE BIOLOGY I T. Higashiyama, Nagoya University, Nagoya, JAPAN

REPRODUCTIVE BIOLOGY II T. Dresselhaus, University of Regensburg, Regensburg, GERMANY

15 16 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

YERSINIA 11 - THE 11TH INTERNATIONAL SYMPOSIUM ON YERSINIA KEYNOTE SPEAKER William Goldman, University of North Carolina at Chapel Hill, USA 第十一届耶尔森菌属国际研讨会 美国北卡罗来纳大学教堂山分校

INVITED SPEAKERS June 24-28 118 Participants Mark Achtman, University College Cork, IRELAND 爱尔兰考克大学 Alzira Almeida, Centro de Pesquisas Aggeu Magalhães, BRASIL Aggeu Magalhães研究中心，巴西 Andrey Anisimov, State Research Center for Applied Microbiology and Biotechnology, RUSSIA 俄罗斯应用微生物与生物技术国家研究中心 ORGANIZED BY James Bliska, Stony Brook University, USA 美国纽约州立大学石溪分校 Ruifu Yang, Beijing Institute of Microbiology and Epidemiology, CHINA Robert Brubaker, University of Kentucky, USA 美国肯塔基大学 中国北京微生物流行病学研究所 Jae-Won Byun, National Veterinary Research and Quarantine Service, KOREA 韩国国立兽医科学检疫院 Elisabeth Carniel, Institut Pasteur, FRANCE 法国巴斯德研究所 Elisabeth Carniel, Institut Pasteur, FRANCE 法国巴斯德研究所 Paul Keim, Northern Arizona University, USA 美国北亚利桑那大学 Zijian Feng, Chinese Center for Disease Control and Prevention, CHINA 中国疾病预防控制中心 Andrey Anisimov, State Research Center for Applied Microbiology and Biotechnology, RUSSIA Jürgen Heesemann, Max von Pettenkofer-Institute, GERMANY Max von Pettenkofer研究所，德国 俄罗斯应用微生物与生物技术国家研究中心 B. Joseph Hinnebusch, NIH, NIAID, Rocky Mountain Labs, USA 美国国立卫生研究院/ 美国过敏和传染病研究所，落基山实验室 Huaiqi Jing, National Institute for Communicable Disease Control and Prevention, CHINA 中国国家传染病预防控制所 Paul Keim, Northern Arizona University, USA 美国北亚利桑那大学 PROGRAM Emanuelle Mamroud, Israel Institute for Biological Research, ISRAEL 以色列生物研究所 Motohiro Matsuura, Kyoto University Graduate School of Medicine, JAPAN 日本京都大学研究生院医学部 PHYSIOLOGY OF YERSINIA I Virginia Miller, University of North Carolina-Chapel Hill, USA 美国北卡莱罗纳大学教堂山分校 W. Goldman, University of North Carolina, Chapel Hill, North Carolina, USA Hristo Najdenski, The Stephan Angeloff Institute of Microbiology-BAS, BULGARIA 保加利亚Stephan Angeloff微生物研究所 R.D. Perry, University of Kentucky, Lexington, Kentucky, USA Robert Perry, University of Kentucky, USA 美国肯塔基大学 Lauriane Quenee, HTRL Animal Research Immunology Core University of Chicago, USA 芝加哥大学动物免疫学研究中心 PHYSIOLOGY OF YERSINIA II Minoarisoa Rajerison, Institut Pasteur de Madagascar, MADAGASCAR 马达加斯加巴斯德研究所 V.L. Miller, University of North Carolina, Chapel Hill, North Carolina, USA Waldemar Rastawicki, National Institute of Public Health-National Institute of Hygiene, POLAND 波兰公共卫生研究所 M. Skurnik, University of Helsinki, Helsinki, FINLAND Feng Shao, National Institute of Biological Sciences, CHINA 中国北京生命科学研究所 Mikael Skurnik, University of Helsinki, FINLAND 芬兰赫尔辛基大学 Nils Christian Stenseth, University of Oslo, NORWAY 挪威奥斯陆大学 PHYSIOPATHIOLOGY AND IMMUNOLOGY OF YERSINIA-CAUSED DISEASES Ruifu Yang, Beijing Institute of Microbiology and Epidemiology, CHINA 中国北京微生物流行病学研究所 J. Hinnebusch, NIAID-Rocky Mountain Laboratories, National Institutes of Health, Hamilton, Montana, USA J. Bliska, Stony Brook University, Stony Brook, New York, USA

EPIDEMIOLOGICAL ASPECTS OF YERSINIA-CAUSED DISEASES R. Yang, Beijing Institute of Microbiology and Epidemiology, Beijing, CHINA H. Najdenski, Bulgarian Academy of Sciences, So a, BULGARIA

DIAGNOSIS AND PREVENTION OF YERSINIA-CAUSED DISEASES A. Anisimov, State Research Center for Applied Microbiology and Biotechnology, Obolensk, RUSSIA N.C. Stenseth, University of Oslo, Blindern, NORWAY

INFECTION AND VIRULENCE OF YERSINIA A.M.P. Almeida, CPqAM/ FIOCRUZ-PE, Recife, BRAZIL R.R. Brubaker, University of Kentucky, Lexington, Kentucky, USA

GENOMICS AND OMICS-DRIVEN STUDY OF YERSINIA P. Keim, Northern Arizona University, Flagstaff, Arizona, USA E. Carniel, Institut Pasteur, Paris, FRANCE

17 18 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

NEW ADVANCES IN OPTICAL IMAGING OF KEYNOTE SPEAKER LIVE CELLS AND ORGANISMS Stefan Hell, Max Planck Institute for Biophysical Chemistry, GERMANY 德国马克斯普朗克生物物理化学研究所 活细胞和有机体的光学成像新进展 INVITED SPEAKERS INTRACELLULAR IMAGING Akihiro Kusumi, Kyoto University, JAPAN 日本京都大学 August 20-23 242 Participants Michiyuki Matsuda, Kyoto University, JAPAN 日本京都大学 Robert Singer, Albert Einstein College of Medicine, USA 美国爱因斯坦医学院

SINGLE MOLECULE IMAGING ORGANIZED BY Toshio Ando, Kanazawa University, JAPAN 日本金泽大学 Atsushi Miyawaki, Riken Brain Science Institute, JAPAN 日本理研所脑科学研究所 Carlos Bustamante, HHMI/ University of California, Berkeley, USA 美国霍华德休斯医学研究院/ 美国加州大学伯克利分校 Xiaoliang Sunney Xie, Harvard University, USA 美国哈佛大学 Yoshie Harada, Kyoto University, JAPAN 日本京都大学 Rafael Yuste, Columbia University, USA 美国哥伦比亚大学 Paul Selvin, University of Illinois at Urbana-Champaign, USA 美国伊利诺伊大学厄本那一香槟分校 Xiaowei Zhuang, HHMI/ Harvard University, USA 美国霍华德休斯医学研究院/ 哈佛大学 Michelle Wang, Cornell University and HHMI, USA 美国康奈尔大学/ 霍华德休斯医学研究所

PROGRAM PROBE DEVELOPMENT SINGLE MOLECULE IMAGING AND MANIPULATION Steven Boxer, Stanford University, USA 美国斯坦福大学 Atsushi Miyawaki, Riken Brain Science Institute, JAPAN 日本理研所脑科学研究所 X. Zhuang, HHMI, Harvard University, Cambridge, Massachusetts, USA Hidekazu Tsutsui, Osaka University, JAPAN 日本大阪大学 PROBE DEVELOPMENT A. Miyawaki, RIKEN Brain Science Institute, Wako, JAPAN SUPER-RESOLUTION MICROSCOPY Long Cai, Caltech, USA 美国加州理工学院 William Moerner, Stanford University, USA 美国斯坦福大学 SUPER RESOLUTION IMAGING Valentin Nagerl, University of Bordeaux, FRANCE 法国波尔多大学 X. Zhuang, HHMI, Harvard University, Cambridge, Massachusetts, USA Xiaowei Zhuang, HHMI/ Harvard University, USA 美国霍华德休斯医学研究院/ 美国哈佛大学

IN VIVO IMAGING IN VIVO IMAGING X.S. Xie, Harvard University, Cambridge, Massachusetts, USA Scott Fraser, University of Southern California, USA 美国南加州大学 Masaru Ishii, Osaka University, JAPAN 日本大阪大学 INTRACELLULAR IMAGING Eric Potma, UC Irvine, USAEric Potma, UC Irvine, USA 美国加州大学欧文分校 A. Miyawaki, RIKEN Brain Science Institute, Wako, JAPAN Michio Tomura, Kyoto University, JAPAN 日本京都大学 Xiaoliang Sunney Xie, Harvard University, USA 美国哈佛大学 OPTICAL MANIPULATION OF ACTIVITY, INCLUDING OPTOGENETICS NEUROIMAGING AND CAGED COMPOUNDS Ann-Shyn Chiang, National Tsing Hua University, TAIWAN 台湾国立清华大学 R. Yuste, Columbia University, New York, New York, USA Daniel Choquet, CNRS-Univ. Bordeaux, FRANCE 法国国家科学研究中心波尔多大学 Adam Cohen, Harvard University, USA 美国哈佛大学 NEUROIMAGING Arthur Konnerth, Technical University Munich, GERMANY 德国慕尼黑理工大学 R. Yuste, Columbia University, New York, New York, USA Wei Min, Columbia University, USA 美国哥伦比亚大学

OPTICAL MANIPULATION OF ACTIVITY, INCLUDING OPTOGENETICS AND CAGED COMPOUNDS Edward Boyden, Massachusetts Institute of Technology, USA 美国麻省理工学院 Roberto Etchenique, Universidad De Buenos Aires, ARGENTINA 阿根廷布宜诺斯艾利斯大学 Michael Lin, Stanford University School of Medicine, USA 美国斯坦福大学医学院 Shimon Weiss, University of California, Los Angeles, USA 美国加州大学洛杉矶分校 Rafael Yuste, Columbia University, USA 美国哥伦比亚大学

19 20 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

CELL SIGNALING IN METABOLISM, INFLAMMATION AND CANCER KEYNOTE SPEAKER 代谢、炎症及癌症中的细胞信号传导 Michael Karin, University of California, USA 美国加州大学 INVITED SPEAKERS Yinon Ben-Neriah, Hebrew University, ISRAEL 以色列耶路撒冷希伯来大学 September 2-6 229 Participants Zhijian "James" Chen, University of Texas Southwestern Medical Center, USA 美国德州大学 西南医学中心 David Cheresh, University of California, USA 美国加州大学 Melanie Cobb, University of Texas Southwestern Medical Center, USA 美国德州大学西南医学中心 ORGANIZED BY Roger Davis, University of Massachusetts Medical Center, USA 美国麻省州立大学医学中心 Michael Karin, University of California, San Diego, USA 美国加州大学圣地亚哥分校 Gen-Sheng Feng, University of California, USA 美国加州大学 Anning Lin, Shanghai Insititute of Biochemistry and Cell Biology, CAS, CHINA Sankar Ghosh, Columbia University, USA 美国哥伦比亚大学 中国科学院生物化学与细胞生物学研究所 Douglas Green, St. Jude Children's Research Hospital, USA 美国圣裘德儿童研究医院 Zheng-Gang Liu, NIH/ NCI, USA 美国国立卫生研究院癌症研究所 Kun-Liang Guan, University of California, USA 美国加州大学 David Wallach, Weizmann Institute of Science, ISRAEL 以色列魏兹曼科学研究所 Alexander Hoffmann, University of California, USA美国加州大学 Lijian Hui, Shanghai Institute of Biochemistry & Cell Biology, CHINA 中国上海生命科学研究院生物化学与细胞生物学研究所 PROGRAM Gary Johnson, University of Carolina, USA 美国加州大学 SIGNALING IN METABOLISM I Ming Li, Memorial Sloan-Kettering Cancer Center, USA 美国纪念斯隆-凯特琳癌症中心 Anning Lin, Shanghai Insititute of Biochemistry and Cell Biology, CAS, CHINA 中国上海生命科学研究院生物化学与细胞生物学研究所 M.H. Cobb, University of Texas Southwestern Medical Center, Dallas, Texas, USA Xin Lin, MD Anderson Cancer Centre, USA 美国MD安德森癌症中心 R. Davis, University of Massachusetts Medical Center, Worcester, Massachusetts, USA Zhenggang Liu, NIH/ NCI, USA 美国国家健康研究院国家癌症研究所 Glenn Merlino, NCI, Laboratory of Cancer Biology and Genetics, USA 美国国家健康研究院国家癌症研究所 SIGNALING IN METABOLISM II Jorge Moscat, Sanford-Burnham Institute, La Jolla, CALIFORNIA 美国斯坦福-伯纳姆医学研究所 R. Davis, University of Massachusetts Medical Center, Worcester, Massachusetts, USA Manolis Pasparakis, University of Cologne, GERMANY 德国科隆大学 Marsha Rosner, University of Chicago, USA 美国芝加哥大学 SIGNALING IN INFLAMMATION/ IMMUNITY I Yufang Shi, Institute of Health Sciences, USA 美国健康科学研究所 Y. Ben-Neriah, Hebrew University, Jerusalem, ISRAEL Shao-Cong Sun, MD Anderson Cancer Centre, USA 美国MD安德森癌症中心 D. Wu, Yale University, New Haven, Connecticut, USA Erwin Wagner, Centro Nacional de Investigaciones Oncologicas (CNIO), SPAIN 西班牙国立癌症研究中心 David Wallach, Weizmann Institute of Science, Israel 以色列魏兹曼科学研究所 Gang Wang, Institute of Biochemistry and Cell Biology, SIBS, CAS, CHINA 中国北京生命研究所 SIGNALING IN INFLAMMATION II Xiaodong Wang, National Institute of Biological Sciences (NIBS) , CHINA 中国北京生命研究所 D. Wallach, Weizmann Institute of Science, Rehovot, ISRAEL Hongyang Wang, Eastern Hepatobiliary Surgery Institute/ Hospital, CHINA 中国东方肝胆外科研究所/ 医院 D. Green, St. Jude Children's Research Hospital, Memphis, Tennessee, USA Hao Wu, Harvard Medical School, USA 美国哈佛大学医学院 Dan Wu, Yale University, USA 美国耶鲁大学 SIGNALING IN INFLAMMATION III S.-C. Sun, University of Texas M.D. Anderson Cancer, Houston, Texas, USA

SIGNALING IN CANCER I Z. Liu, NCI, National Institutes of Health, Bethesda, Maryland, USA

SIGNALING IN CANCER II E. Wagner, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, SPAIN M. Rosner, University of Chicago, Illinois, USA

SIGNALING IN CANCER III T. Kallunki, Danish Cancer Society Research Center, Copenhagen, DENMARK

21 22 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

MOLECULAR BASIS OF AGING AND DISEASE KEYNOTE SPEAKERS Adam Antebi, Max Planck Institute for Biology of Ageing, GERMANY 德国马克斯·普朗克衰老生物学研究所 衰老和疾病的分子基础 Judith Campisi, Buck Institute for Research on Aging and Lawrence Berkeley National Laboratory, USA 美国BUCK衰老研究所/ 美国劳伦斯伯克利国家实验室 Leonard Guarente, Massachusetts Institute of Technology, USA 美国麻省理工学院 September 9-13 169 Participants Cynthia Kenyon, Department of Biochemistry and Biophysics, University of California San Francisco, USA 美国加州大学洛杉矶分校, 生化与生物物理系 Hong Gil Nam, Center for New Biology of Plant Senescence and Life History, IBS & DGIST, KOREA 韩国韩国大邱庆北科学技术院, 植物衰老和生命历史新生物学中心 Linda Partridge, University College London, UNITED KINGDOM 英国伦敦大学学院 ORGANIZED BY Zhongjun Zhou, The University of Hong Kong, CHINA 香港大学 Adam Antebi, Max Planck Institute, GERMANY 德国马克斯·普朗克研究所 Jing-Dong Jackie Han, Partner Institute for Computational Biology, CHINA 中科院-马普学会计算生物学伙伴研究所 INVITED SPEAKERS Brian Kennedy, Buck Institute, USA 美国BUCK研究所 Vilhelm Bohr, Biomedical Research Center, USA 美国生物医学研究所 Jan Vijg, Albert Einstein College of Medicine, USA 美国艾伯特爱因斯坦医学院 Anne Brunet, Stanford University, USA 美国斯坦福大学 Mario Fraga, Centro Nacional de Biotecnología/ CNB-CSIC and IUOPA, SPAIN PROGRAM Jing-Dong Jackie Han, Partner Institute for Computational Biology, CHINA 中科院-马普学会计算生物学伙伴研究所 METABOLISM I Jan Hoeijmakers, Erasmus University Rotterdam, THE NETHERLANDS 荷兰鹿特丹伊拉斯姆斯大学 Eun Seong Hwang, University of Seoul, SOUTH KOREA 韩国首尔大学 V. Longo, University of Southern California, Los Angeles, California, USA Matt Kaeberlein, University of Washington, USA 美国华盛顿大学 Brian Kennedy, Buck Institute, USA 美国BUCK研究所 METABOLISM II Philipp Khaitovich, CAS-MPG Institute for Computational Biology, CHINA 中国科学院-马普学会计算生物学伙伴研究所 V. Bohr, Biomedical Research Center, Baltimore, Maryland, USA Stuart Kim, Stanford University Medical Center, USA 美国斯坦福大学医学院 T. Nakagawa, University of Toyama, JAPAN Seung-Jae Lee, Pohang University of Science and Technology, KOREA 韩国浦项科技大学 Siu Sylvia Lee, Cornell University, USA 美国康奈尔大学 DEVELOPMENTAL AND ENVIRONMENTAL INTERACTION I Hao Li, University of California, San Francisco, USA 美国加州大学洛杉矶分校 A. Antebi, Max Planck Institute for the Biology of Ageing, Cologne, GERMANY Valter Longo, University of Southern California, USA 美国南加州大学 Nozomu Mori, Nagasaki University School of Medicine, JAPAN 日本长崎大学医学部 Takaomi Saido, RIKEN Brain Science Institute, JAPAN 日本理研所脑科学研究所 DEVELOPMENTAL AND ENVIRONMENTAL INTERACTION II Isao Shimokawa, Nagasaki University Graduate School of Biomedical Sciences, JAPAN 日本长崎大学生物医学科学研究生院 M. Fraga, Centro Nacional de Biotecnología/ CNB-CSIC and IUOPA, Oveido, SPAIN Colin Stewart, Institute of Medical Biology, SINGAPORE 新加坡医学生物学研究所 Z. Songyang, Baylor College of Medicine, Houston, Texas, USA/ Sun Yat-Sen University, Guangzhou, CHINA Yousin Suh, Albert Einstein College of Medicine, USA 美国艾伯特爱因斯坦医学院 Xiaoli Tian, Peking University, CHINA 中国北京大学 MOLECULAR AND CELLULAR INTERVENTIONS I Jan Vijg, Albert Einstein College of Medicine, USA 美国艾伯特爱因斯坦医学院 Z. Zhou, University of Hong Kong, CHINA Meng Wang, Baylor College of Medicine, USA 美国贝勒医学院 Zhuohua Zhang, Central South University, CHINA 中国中南大学 Jinqiu Zhou, Institute of Biochemistry and Cell Biology, CAS, CHINA 中国科学院上海生物化学与细胞生物学研究所 MOLECULAR AND CELLULAR INTERVENTIONS II Songyang Zhou, Sun Yat-sen University, CHINA 中国中山大学 M. Kaeberlein, University of Washington, Seattle, Washington, USA B. Kennedy, Buck Institute, Novato, California, USA

SYSTEMS AGING AND CELLULAR ENDPOINTS I J. Vijg, Albert Einstein College of Medicine, Bronx, New York/ Institute of Biochemistry and Cell Biology, CAS, Shanghai, CHINA

SYSTEMS AGING AND CELLULAR ENDPOINTS II X. Tian, Peking University, Beijing, CHINA

COMPARATIVE BIOLOGY OF AGING AND DNA DAMAGE AND REPAIR Y. Suh, Albert Einstein College of Medicine, Bronx, New York USA

23 24 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

FRONTIERS IN BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 生物信息学和计算生物学的前沿研究

September 23-27 151 Participants

ORGANIZED BY M. Madan Babu, MRC-Laboratory of Molecular Biology, UK 英国医学研究委员会分子生物实验室 Luonan Chen, Shanghai Institutes for Biological Sciences, CAS, CHINA 中国科学院上海生命科学研究院 Keith Dunker, Indiana University School of Medicine, USA KEYNOTE SPEAKERS Leroy Hood, Institute for Systems Biology, USA 美国印第安纳大学医学院 美国系统生物学研究所 Joel Sussman, Weizmann Institute of Science, ISRAEL Satoru Miyano, University of Tokyo, JAPAN 日本东京大学 以色列魏兹曼科学研究所 Marc Vidal, Harvard Medical School and Dana-Farber Cancer Institute, USA Dong Xu, University of Missouri, USA 美国密苏里大学 美国哈佛医学院丹娜-法伯癌症研究所

PROGRAM INVITED SPEAKERS Kazuyuki Aihara, University of Tokyo, JAPAN 日本东京大学 GENOMICS AND PERSONALIZED MEDICINE Steven E. Brenner, University of California, Berkeley, USA 美国加州大学伯克利分校 S. Miyano, University of Tokyo, JAPAN Luonan Chen, Shanghai Institutes for Biological Sciences, CAS, CHINA 中国科学院上海生命科学研究院 Phoebe Chen, La Trobe University, AUSTRALIA 澳大利亚拉筹伯大学 INTERACTOMES AND NETWORKS Kwang-Hyun Cho, Korea Advanced Institute of Science and Technology (KAIST), REPUBLIC OF KOREA 韩国科学技术院 K. Dunker, Indiana University School of Medicine, Indianapolis, USA Keith Dunker, Indiana University School of Medicine, USA 美国印第安纳大学医学院 Bailin Hao, Chinese Academy of Sciences/ Fudan University, CHINA 中国科学院/ 复旦大学 Xionglei He, Sun Yat-sen University, CHINA 中国中山大学 COMPUTATIONAL DISEASES STUDIES Daisuke Kihara, Purdue University, USA 美国普渡大学 J. Sussman, Weizmann Institute of Science, Rehovot, ISRAEL Xiaole Liu, Dana-Farber Cancer Institute, USA/ Tongji University, CHINA 美国丹娜-法伯癌症研究所/ 中国同济大学 Stephen Michnick, Université de Montreal, CANADA 加拿大蒙特利尔大学 GENOME ANALYSIS Satoru Miyano, University of Tokyo, JAPAN 日本京东大学 D. Kihara, Purdue University, West Lafayette, Indiana, USA Hong Gil Nam, Center for New Biology of Plant Senescence and Life History, IBS & DGIST, KOREA 韩国大邱庆北科学技术院 Balaji Santhanam, MRC-Laboratory of Molecular Biology, UK 英国医学研究委员会分子生物实验室 GENE REGULATION Bairong Shen, Soochow University, CHINA 中国苏州大学 Collin M. Stultz, Harvard-MIT Division of Health Sciences and Technology, USA 哈佛-麻省理工卫生科学与技术部 B. Santhanam, MRC Laboratory of Molecular Biology, Cambridge, UNITED KINGDOM Sarah Teichmann, MRC Laboratory of Molecular Biology, UK 英国医学研究委员会分子生物实验室 Henry Wan, Mississippi State University, USA 美国密西西比州立大学 COMPUTATIONAL SYSTEMS BIOLOGY Dong Xu, University of Missouri, USA 美国密苏里大学 L. Chen, Shanghai Institutes for Biological Sciences, CAS, CHINA Ying Xu, University of Georgia, USA 美国乔治亚大学 Michael Zhang, University of Texas-Dallas, USA/ Tsinghua University, CHINA 美国德州大学达拉斯分校/ 中国清华大学 FUNCTION, STRUCTURE AND EVOLUTION Zemin Zhang, Genentech Inc, USA 美国基因工程技术公司 S. Brenner, University of California, Berkeley, USA Zhongming Zhao, Vanderbilt University Medical Center, USA 美国范德堡大学医学中心

25 26 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

CSHA/ ISSCR JOINT MEETING ON STEM CELLS IN SCIENCE AND MEDICINE KEYNOTE SPEAKERS Janet Rossant, The Hospital for Sick Children/ University of Toronto, CSHA/ ISSCR 合作会议: 科学和医学领域的干细胞研究 Canada 加拿大儿童医院/ 加拿大多伦多大学 Richard Young, Whitehead Institute/ M.I.T., USA 美国麻省理工学院怀特 海生物医学研究所 October 14-17 375 Participants INVITED SPEAKERS Tao Cheng, University of Pittsburgh, USA 美国匹兹堡大学 Sheng Ding, University of California, San Francisco, USA 美国加州大学洛杉矶分校 ORGANIZED BY Anna-Katerina Hadjantonakis, Memorial Sloan Kettering, USA 美国斯隆凯特林癌症研究中心 Catriona Jamieson, University of California, San Diego, USA 美国加州大学洛杉矶分校 Hongkui Deng, Peking University, College of Life Sciences, CHINA 北京大学生命科学学院 Ryoichiro Kageyama, Kyoto University, JAPAN 日本京都大学 Andrew Elefanty, Monash University, AUSTRALIA 澳大利亚莫纳什大学 Timothy Kieffer, University of British Columbia, CANADA 加拿大英属哥伦比亚大学 Ronald McKay,The Lieber Institute for Brain Development, USA 美国Lieber脑发育研究所 En Li, China Novartis Institutes for Biomedical Research, CHINA 中国诺华生物医学研究所 Huck-Hui Ng, Genome Institute of Singapore, SINGAPORE 新加坡基因组研究所 Linheng Li, Stowers Institute for Medical Research, USA 美国斯托瓦斯医学研究所 Richard Young, Whitehead Institute/M.I.T., USA 美国麻省理工学院怀特海生物医学研究所 Christine Mummery, Leiden University Medical Center, THE NETHERLANDS 荷兰莱顿大学医学中心 Huck-Hui Ng, Genome Institute of Singapore, SINGAPORE 新加坡基因组研究所 PROGRAM Hideyuki Okano, Keio University School of Medicine, JAPAN 日本庆应义塾大学医学部 IPS AND REPROGRAMMING Duanqing Pei, Guangzhou Institute of Biomedicine and Health, CAS, CHINA 中国科学院广州生物医药与健康研究院 H.H. Ng, Genome Institute of Singapore, SINGAPORE Kathrin Plath, UCLA School of Medicine, USA 美国加州大学洛杉矶分校医学院 Jose Polo, Monash University, AUSTRALIA 澳大利亚莫纳什大学 Bing Ren, Ludwig Institute for Cancer Research, USA 美国路德维希癌症研究所 CIRCUITRY AND GLOBAL TOOLS Edouard Stanley, Monash University, AUSTRALIA 澳大利亚莫纳什大学 R.A. Young, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA Atsushi Suzuki, Kyushu University, JAPAN 日本九州大学 Masayo Takahashi, RIKEN Center for Developmental Biology, JAPAN 日本理化研究所发育生物学研究中心 CANCER STEM CELLS AND THERAPY Patrick Tam, Children's Medical Research Institute, AUSTRALIA 澳大利亚儿童医学研究中心 J. Rossant, Hospital for Sick Children, Toronto, CANADA Yixian Zheng, Carnegie Institution for Science, USA 美国卡耐基科学研究所 Zhong Zhong, GlaxoSmithKline, CHINA 葛兰素史克（中国）投资有限公司 STEM CELLS AND DEVELOPMENT Qi Zhou, Institute of Zoology, CAS, CHINA 中国科学院动物研究 Qiao Zhou, Harvard University, USA 美国哈佛大学 H. Deng, Peking University College of Life Sciences, Beijing, CHINA

REGENERATIVE PHARMACOLOGY AND TISSUE ENGINEERING R.D. McKay, The Lieber Institute for Brain Development, Baltimore, Maryland, USA

CELL FATE CONTROL AND CONVERSION A. Elefanty, Monash University, Victoria, AUSTRALIA

27 28 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

DEVELOPMENT, FUNCTION AND DISEASE OF NEURAL CIRCUITS KEYNOTE SPEAKERS Eric Nestler, Mount Sinai School of Medicine, USA 美国西奈山医学院 神经回路的发育、功能和疾病 Larry Zipursky, HHMI, University of California, Los Angeles, USA 美国霍华德·休斯医学研究所/加州大学洛杉矶分校

INVITED SPEAKERS October 21-25 122 Participants Paola Arlotta, Harvard University, USA 美国哈佛大学 Chinfei Chen, Harvard Medical School, Children's Hospital, USA 美国哈佛大学/ 波士顿儿童医院 Gregoire Courtine, Swiss Federal Institute of Technology (EPFL), SWITZERLAND 瑞士洛桑联邦理工大学 Yang Dan, University of California, Berkeley, USA 美国加州大学伯克利分校 Aaron DiAntonio, Washington University School of Medicine, USA 美国华盛顿大学医学院 ORGANIZED BY Jiulin Du, Institute of Neuroscience, CAS, CHINA 中国科学院神经科学研究所 Shumin Duan, Zhejiang University School of medicine, CHINA 中国浙江大学医学院 Barry Dickson, Research Institute of Molecular Pathology, AUSTRIA 奥地利分子病理学研究所 Martyn Goulding, The Salk Institute, USA 美国萨克生物研究学院 Zhigang He, Harvard Medical School/ Children's Hospital, Boston, USA 美国哈佛大学医学院/ 波士顿儿童医院 Marc Hammarlund, Yale University, USA 美国耶鲁大学 Hitoshi Okamoto, RIKEN Brain Science Institute, JAPAN 日本理研所脑科学研究所 Zhigang He, Harvard Medical School/ Children's Hospital, Boston, USA 美国哈佛大学/ 波士顿儿童医院 Yimin Zou, University of California at San Diego, USA 美国加州大学圣地亚哥大学 Hailan Hu, Shanghai Institutes for Biological Sciences, CHINA 中国科学院上海生命科学研究院 Yishi Jin, University of California, San Diego/ HHMI, USA 美国加州大学圣地亚哥大学/ 霍华德休斯医学研究所 PROGRAM Joshua Kaplan, Massachusetts General Hospital/ Harvard Med., USA 美国麻省综合医院/ 美国哈佛大学医学院 SPECIAL LECTURE Hitoshi Okamoto, RIKEN Brain Science Institute, JAPAN 日本理研所脑科学研究所 H. Okamoto, RIKEN Brain Science Institute, Wako, JAPAN Franck Polleux, The Scripps Research Institute, USA 美国斯克里普斯研究所 Mu-Ming Poo, Institute of Neuroscience, Chinese Academy of Sciences, CHINA 中国科学院神经科学研究所 Botond Roska, Friedrich Miescher Institute, SWITZERLAND 瑞士弗雷德里希 米歇尔生物医学研究所 CIRCUIT ASSEMBLY I Thomas Schwarz, Children's Hospital and Harvard Medical School, USA 美国哈佛医学院/波士顿儿童医院 B. Ye, University of Michigan, Ann Arbor, Michigan, USA Mark Tuszynski, University of California San Diego, USA 美国加州大学圣迭戈分校 Fan Wang, Duke University, USA 美国杜克大学 CIRCUIT AND BEHAVIOR I Hongyan Wang, Duke-NUS, SINGAPORE 新加坡杜克-新加坡国立大学 K. Miyamichi, University of Tokyo, Tokyo, JAPAN Wei Xie, Southeast University, CHINA 中国东南大学 Michisuke Yuzaki, Keio University, JAPAN 日本庆应义塾大学 NEURAL CIRCUIT REPAIR I Yimin Zou, University of California at San Diego, USA 美国加州大学圣迭戈分校 L. Ma, University of Southern California, Los Angeles, California, USA

CIRCUIT ASSEMBLY II Q. Lu, Beckman Research Institute of the City of Hope, Duarte, California, USA

CIRCUIT DYSFUNCTION T. Watkins, Genentech, Inc., South San Francisco, California, USA

CIRCUIT AND BEHAVIOR II G. Ou, Institute of Biophysics, CAS, Beijing, CHINA

CIRCUIT REPAIR II H. Zou, Mount Sinai School of Medicine, New York, New York, USA

29 30 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

TUMOR IMMUNOLOGY AND IMMUNOTHERAPY KEYNOTE SPEAKERS David Baltimore, California Institute of Technology, USA 美国加利福尼亚技术研究所 肿瘤免疫及免疫疗法 Xiaodong Wang, National Institute of Biological Sciences, CHINA 中国北京生命科学研究所

INVITED SPEAKERS October 28 - November 1 274 Participants Jean Pierre Abastado, Singapore Immunology Network, SINGAPORE 新加坡免疫学网络中心 Jannie Borst, The Netherlands Cancer Institute, THE NETHERLANDS 荷兰癌症研究所 Jay Berzofsky, National Cancer Institute, USA 美国国家癌症研究所 Vincenzo Bronte, University of Verona, ITALY 意大利维罗纳大学 Xuetao Cao, Chinese Academy of Medical Sciences, CHINA 中国医学科学院 Yuan Chang, University of Pittsburgh Cancer Institute, USA ORGANIZED BY 美国匹兹堡大学癌症研究所 Lieping Chen, Yale School of Medicine, USA 美国耶鲁大学医学院 Xuetao Cao, Chinese Academy of Medical Sciences, CHINA 中国医学科学院 Olivera Finn, University of Pittsburgh School of Medicine, USA 美国匹兹堡大学癌症研究所 Xin-Yuan Fu, National University of Singapore, SINGAPORE 新加坡国立大学 Xin-Yuan Fu, National University of Singapore, SINGAPORE Olivera Finn, University of Pittsburgh School of Medicine, USA 新加坡国立大学 Yang-Xin Fu, The University of Chicago, USA 美国芝加哥大学 美国匹茨堡大学医学院 Yukai He, Georgia Regents University Cancer Center, USA Cornelis Melief, Leiden University Medical Center, THE NETHERLANDS 美国格鲁吉亚摄政大学癌症中心 Erica Jensen Jarolim, Medical University Vienna, AUSTRIA 奥地利维也纳医科大学 荷兰莱顿大学医学中心 Dieter Kabelitz, University of Kiel, GERMANY 德国基尔大学 Yutaka Kawakami, Keio University School of Medicine, JAPAN 日本庆应义塾大学医学部 PROGRAM Binfeng Lu, University of Pittsburgh School of Medicine, USA 美国匹茨堡大学医学院 CANCER, INFLAMMATION AND IMMUNOSUPPRESSION Ignacio Melero, University of Navarra, SPAIN 西班牙纳瓦拉大学 M. Smyth, Queensland Institute of Medical Research, Brisbane, AUSTRALIA Cornelis Melief, Leiden University Medical Center, THE NETHERLANDS 荷兰莱顿大学医学中心 Ira Mellman, Genentech, USA 美国基因技术公司 Andrew Mellor, Georgia Regents University, USA 美国格鲁吉亚摄政大学 IMMUNE ESCAPE OF CANCER Graham Pawelec, University of Tuebingen Center for Medical Research, GERMANY 德国图宾根大学医学研究中心 G. Pawelec, University of Tübingen, GERMANY Zhihai Qin, Chinese Academy of Sciences, CHINA 中国科学院 Michel Sadelain, Memorial Sloan-Kettering Cancer Center, USA 美国纪念斯隆-凯特琳癌症中心 ADOPTIVE T CELL THERAPY Mark Smyth, Queensland Institute of Medical Research in Brisbane, AUSTRALIA 澳大利亚昆士兰医学研究所 M. Sadelain, Memorial Sloan-Kettering Cancer Center, New York, New York, USA Cassian Yee, UT MD Anderson Cancer Center, USA 美国德州大学MD安德森癌症中心 Hua Yu, City of Hope Duarte, USA 美国霍普城市学院（杜瓦安蒂） ANTIBODY THERAPY Rong-Fu Wang, The Methodist Hospital Research Institute Houston, USA 美国卫理公会医院研究所 Limin Zheng, Sun Yat-sen University, CHINA 中国中山大学 L. Chen, Yale University School of Medicine, New Haven, Connecticut, USA Weiping Zou, University of Michigan Medical School, USA 美国密歇根州立大学医学医院 CANCER VACCINES J. Berzofsky, NCI, National Institutes of Health, Bethesda, Maryland, USA

COMBINATION OF IMMUNOTHERAPY WITH OTHER THERAPIES I. Mellman, Genentech, South San Franciso, CALIFORNIA

NEW APPROACHES TO IMMUNOTHERAPY OF CANCER H. Yu, Beckman Research Institute at City of Hope, Duarte, California, USA

31 32 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

NUCLEAR RECEPTORS AND DISEASES KEYNOTE SPEAKER 核受体与代谢 Mitchell A. Lazar, University of Pennsylvania, USA 美国宾夕法尼亚大学

INVITED SPEAKERS Sung Hee Baek, Seoul National University, KOREA 韩国首尔国立大学 November 4-8 119 Participants Ajay Chawla, University of California, San Francisco, USA 美国加州大学洛杉矶分校 Hueng-Sik Choi, Chonnam National University, SOUTH KOREA 韩国国立全南大学 Gen-Shen Feng, University of California, USA 美国加州大学 Vincent Giguere, McGill University, CANADA 加拿大麦吉尔大学 Christopher Glass, University of California, San Diego, USA 美国加州大学洛杉矶分校 ORGANIZED BY Wendong Huang, Beckman Research Institute of City of Hope, USA 美国希望之城贝克曼研究所 Satoshi Inoue, The University of Tokyo, JAPAN 日本东京大学 Hueng-Sik Choi, Chonnam National University, SOUTH KOREA 韩国国立全南大学 Steven Kliewer, UT Southwestern, USA 德州大学西南医学中心 David Moore, Baylor College of Medicine, USA 美国贝勒医学院 Juro Sakai, The University of Tokyo, JAPAN Kristina Schoonjans, Ecole Polytechnique Fédérale de Lausanne, SWITZERLAND 日本东京大学 Mi-Ock Lee, Seoul National University, KOREA 韩国首尔国立大学 瑞士洛桑联邦理工大学 Xiaoying Li, Shanghai Institute of Endocrinology and Metabolism, CHINA 中国上海市内分泌代谢病研究所 Nanping Wang, Xi’an Jiaotong University School of Medicine, CHINA 中国西安交通大学医学院 Susanne Mandrup, University of Southern Denmark, DENMARK 丹麦南方大学 David Moore, Baylor College of Medicine, USA 美国贝勒医学院 PROGRAM Antonio Moschetta, Consorzio Mario Negri Sud, ITALY STRUCTURE AND FUNCTION Kristina Schoonjans, Ecole Polytechnique Fédérale de Lausanne, Lausanne, SWITZERLAND 瑞士洛桑联邦理工大学 J. Xu, Baylor College of Medicine, Houston, Texas, USA Ming-Jer Tsai, Baylor College of Medicine, USA 美国贝勒医学院 M.J. Tsai, Baylor College of Medicine, Houston, Texas, USA Meng Wang, Baylor College of Medicine, USA 美国贝勒医学院 Nanping Wang, Xi’an Jiaotong University School of Medicine, CHINA 中国西安交通大学医学院 Mitsuhiro Watanabe, Keio University, JAPAN 日本庆应义塾大学 LIVER NUTRIENT METABOLISM, STEATOSIS AND FIBROSIS Eric Xu, Shanghai Institute of Materia Medica, CHINA 中国医学院药物研究所 K. Schoonjans, École Polytechnique Fédérale, Lausanne, SWITZERLAND Jianming Xu, Baylor College of Medicine, USA 美国贝勒医学院 S. Kliewer, UT Southwestern Medical School, Dallas, Texas, USA Xiao-kun Zhang, Xiamen University, CHINA 中国厦门大学

ENERGY BALANCE S. Tsai, Baylor College of Medicine, Houston, Texas, USA D. Moore, Baylor College of Medicine, Houston, Texas, USA

METABOLIC SYNDROME S. Mandrup, University of Southern Denmark, Odense, DENMARK J. Sakai, University of Tokyo, JAPAN

LIVER AND BILE ACIDS V. Giguere, McGill University, Montréal, CANADA X. Li, Shanghai Jiaotong University, Shanghai, CHINA

IMMUNITY, INFLAMMATION AND STEROIDS C. Glass, University of California-San Diego, La Jolla, California, USA A. Chawla, University of California-San Francisco, San Francisco, California, USA

CANCER N. Wang, Xi’an Jiaotong University School of Medicine, Xi'an, CHINA X. Zhang, Xiamen University, Xiamen, China

33 34 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

BACTERIAL INFECTION AND HOST DEFENSE KEYNOTE SPEAKER 细菌感染和宿主防御 Thomas F. Meyer, Max Planck Institute for Infection Biology, GERMANY 德国马克斯·普朗克感染生物学研究所

INVITED SPEAKERS November 18-22 223 Participants Andreas Baumler, University of California at Davis, USA 美国加州大学戴 维斯分校 John Brumell, University of Toronto, CANADA 加拿大多伦多大学 Zhijian "James" Chen, University of Texas Southwestern Medical Center, USA 美国德州大学西南医学中心 ORGANIZED BY Jeffery S. Cox, University of California, USA 美国加州大学 B. Brett Finlay, University of British Columbia, CANADA 加拿大英属哥伦比亚大学 Sam Miller, University of Washington, USA 美国华盛顿大学 Baoxue Ge, Tongji University School of Medicine-Shanghai Pulmonary Hospital, CHINA 中国同济大学附属肺科医院 Craig Roy, Yale University School of Medicine, USA 美国耶鲁大学医学院 Gisou Van Der Goot, Ecole Polytechnique Fédérale de Lausanne, SWITZERLAND Feng Shao, National Institute of Biological Sciences, CHINA 瑞士洛桑联邦理工大学 Karen Guillemin, University of Oregon, USA 美国俄勒冈大学 中国北京生命科学研究所 Wayne Lencer, Harvard Medical School, USA Gisou Van Der Goot, Ecole Polytechnique Fédérale de Lausanne, 美国哈佛大学医学院 Sam Miller, University of Washington, USA 美国华盛顿大学 SWITZERLAND 瑞士洛桑联邦理工大学 Joseph Mougous, University of Washington, USA 美国华盛顿大学 Byung-Ha Oh, Department of Biological Sciences, KAIST, KOREA 韩国科学技术院 PROGRAM Kim Orth, University of Texas Southwestern Medical Center, USA 美国德州大学西南医学中心 BACTERIAL INTERACTION WITH THE AUTOPHAGY Matteo Dal Peraro, École Polytechnique Fédérale de Lausanne-EPFL, SWITZERLAND 瑞士洛桑联邦理工大学 Stefan Raunser, Max-Planck-Institute of Molecular Physiology, GERMANY 德国马克斯·普朗克分子生理学研究所 SYSTEM Yasuko Rikihisa, The Ohio State University, USA 国俄亥俄州立大学 C. Roy, Yale University School of Medicine, New Haven, Connecticut, USA Ilan Rosenshine, The Hebrew University of Jerusalem, ISRAEL 以色列耶路撒冷希伯来大学 Craig Roy, Yale University School of Medicine, USA 美国耶鲁大学医学院 NEW EFFECTOR FUNCTION AND STRUCTURE David G. Russell, Cornell University, USA 美国康奈尔大学 S. Miller, University of Washington, Seattle, USA Olaf Schneewind, The University of Chicago, USA 美国芝加哥大学 Feng Shao, National Institute of Biological Sciences, CHINA 中国上海生命科学院 BACTERIAL RESPONSES TO HOST IMMUNITY Hao Shen, Shanghai Jiaotong University School of Medicine, Shanghai, CHINA and University of Pennsylvania Perelman School of Medicine, USA 中国上海交通大学医学院/ 美国宾夕法尼亚大学Perelman医学院 B.B. Finlay, University of British Columbia, Vancouver, CANADA Michael Starnbach, Harvard Medical School, USA 美国哈佛大学医学院 Patrick Tan, Genome Institute of Singapore, SINGAPORE 新加坡基因组研究所 PORE FORMING TOXINS Victor Torres, Microbial Pathogenesis Program Smilow Research Center, USA 美国斯米洛研究中心 B. Ge, Tongji University, Shanghai, CHINA Raphael Valdivia, Duke University Medical Center, USA 美国杜克大学医学院 Tamotsu Yoshimori, Graduate School of Medicine, Osaka University, JAPAN 日本大阪大学医学部研究生院 INNATE IMMUNE SENSING OF BACTERIAL INFECTION Yongqun Zhu, Life Science Institute, Zhejiang University, CHINA 中国浙江大学生命科学学院 I. Rosenshine, Hebrew University, Jerusalem, ISRAEL

GENETICS, GENOMICS AND VIRULENCE K. Orth, UT Southwestern Medical Center, Dallas, Texas, USA

COMMENSALS AND MICROBIOTA G. van der Goot, Ecole Polytechnique Fédérale de Lausanne, SWITZERLAND

35 36 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia 2013 CONFERENCE AND COURSE PROGRAM / Cold Spring Harbor Asia

THE 4TH JOINT SUMMER SCHOOL ON COMPUTATIONAL AND COGNITIVE NEUROSCIENCE (CCN) 第四期计算认知神经生物学暑期班

July 6-24, 2013

The 4th Computational and Cognitive Neurobiology Summer School was held in the campus of Beijing Normal Sponsored by Beijing Normal University, NYU University, in Beijing, China. The objective of this course was to train in Computational Neuroscience talented and Shanghai, Hugo Shong and the McGovern Institute, highly motivated students and postdocs from Asia and other countries in the world. Applicants with either MIT McGovern Institute, Peking University, Tsinghua quantitative, including Physics, Mathematics, Engineering and Computer Science or experimental background University and Cold Spring Harbor Asia were welcomed. The lectures introduced the basic concepts and methods, as well as cutting-edge research, in Computational Systems and Cognitive Neurosciences, with an emphasis on higher cognitive functions and their underlying neural basis. Modeling were taught at multiple levels, ranging from single neuron computation, microcircuits and large-scale systems, to normative theoretical approach to brain functions. Matlab-based programming labs coordinated with the lectures provided practical training in important computational INSTRUCTORS methods. Xiao-Jing Wang, Yale University School of Medicine, USA 美国耶鲁大学医学院 Si Wu, Institute of Neuroscience, Shanghai, CHINA 中国科学院上海生命科学研 究院神经科学研究所 Upinder S Bhalla, Natl Ctr Biological Science, Bangalore, INDIA 印度国立生物科 学中心 Zachary F Mainen, Instituto Gulbenkian de Ciência, PORTUGAL 葡萄牙古尔班基 安科学研究所

INVITED LECTURERS Matthew Botvinick, Princeton University, USA 美国普林斯顿大学 Mark Churchland, Columbia University, USA 美国哥伦比亚大学 Bob Desimone, Massachusetts Institute of Technology, USA 美国麻省理工大学 Michael Hausser, University College London, UK 英国伦敦大学学院 Eve Marder, Brandeis University, USA 美国布兰代斯大学 Tony Movshon, New York University, USA 美国纽约大学也 Bill Newsome, Stanford University, USA 美国斯坦福大学 Bob Shapley, New York University, USA 美国纽约大学 Misha Tsodyks, Weizmann Institute, ISRAEL 以色列魏茨曼科学研究学院 Xiaoqin Wang, Johns Hopkins University, USA 美国约翰·霍普金斯大学 Kechen Zhang, Johns Hopkins University, USA 美国约翰·霍普金斯大学

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THE 86th ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY CSHA SESSION 第 86 界日本生化学会大会冷泉港亚洲专场

September 12, 2013

CHAIRPERSONS Maoyen Chi, Cold Spring Harbor Asia, China 冷泉港亚洲 Mutsuhito Ohno, Kyoto University, Japan 京都大学

PROGRAM PLENARY LECTURE INTERNATIONAL SESSION: RNA biology

INVITED SPEAKERS Narry Kim, Seoul National University, Korea 国立首尔大学 Huck-Hui Ng, Genome Institute of Singapore, Singapore 新加坡基因组研究所 Yijun Qi, Tsinghua University, China 清华大学 Mutsuhito Ohno, Kyoto University, Japan 京都大学 Michael Rosenfeld, University of California, USA 加利福尼亚大学

SUMMARY In collaboration with the Japanese Biochemistry Society (JBS) we hosted an independent session at JBS’ s 86th annual meeting in Yokohama. This CSHA session in Japan addressed the latest developments in epigenetics, involved an outstanding cast of international scientists from Singapore, Korea, USA, China and Japan, and embodied the same scienti c spirit and open discussion as our meetings in Suzhou and Cold Spring Harbor.

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CSH ASIA FELLOWSHIPS PLANT CELL AND DEVELOPMENTAL BIOLOGY CSHA/ ISSCR JOINT MEETING ON STEM CELLS Chia-yang Chen, National Taiwan University, Taipei, TAIWAN IN SCIENCE AND MEDICINE 冷泉港亚洲奖学金 Chin-Lin Chung, National Sun Yat-sen University, Kaohsiung, Haiyang Chen, Carnegie Institution for Science, Baltimore, Taiwan; Academia Sinica, Tainan, TAIWAN Maryland. USA Ya-wen Hsu, Academia Sinica, Taipei, Taiwan; National Qingfei Jiang, University of California-San Diego, La Jolla, Taiwan University, Taipei, TAIWAN California. USA Dacheng Liang, CSIRO, Canberra, AUSTRALIA Betty Chang, Mount Sinai School of Medicine, New York, USA. Organizers of each CSH Asia meeting select fellowship awards from the Eunmi Park, Harvard Medical School/ Dana-Farber Cancer submitted abstracts by graduate students and postdoc fellows based on the merit YERSINIA 11 Institute, Boston, Massachusetts. USA Kevin Huang, University of California-Los Angeles, Los Angeles, Miqdad Dhariwala, University of Missouri, USA of scienti c quality. California, USA Boris Schmid, University of Oslo, NORWAY Sisi Feng, Shanghai Institutes for Biological Sciences, CAS, Richard Saint, Dstl, UK Shanghai, CHINA Gerty Vanantwerpen, UGent, BELGIUM Congratulations to the following students! Their presentations (short talks or Development, Function and Disease of Neural Circuits Karolina Skorek, University of Warsaw, POLAND posters) were selected for a CSHA fellowship in 2013. Kun Li, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, CHINA NEW ADVANCES IN OPTICAL IMAGING OF Tong-Wey Koh, Yale University, New Haven, Connecticut, USA MECHANISMS AND FUNCTIONS OF NON-APOPTOTIC CELL DEATH LIVE CELLS AND ORGANISMS Haihuai He, VIB & University of Leuven, Leuven, BELGIUM Wanze Chen, Xiamen University, CHINA Guisheng Zhong, Harvard University, USA Ting Liu, Graduate School of Pharmaceutical Science, University of Tokio, JAPAN Qian Su, BIOPIC, Peking University, CHINA TUMOR IMMUNOLOGY AND Joanne M. Hildebrand, The Walter and Eliza Hall Institute of Medical Research, University of Ziqing Zhao, Harvard University, USA Melbourne, AUSTRALIA Lu Wei, Columbia University, USA IMMUNOTHERAPY Lei Huang, Georgia Regents University, Augusta, Georgia, USA Keren Yacobi-Sharon, Weizmann Institute of Science, ISRAEL Sheldon J.J.. Kwok, Harvard Medical School, USA Jinyan Liu, Zhengzhou University, Zhengzhou, CHINA Jun Chu, Stanford University, USA Maarten A. Ligtenberg, Cancer Center Karolinska, Stockholm, Yi Liao, University of Michigan, USA FRANCIS CRICK SYMPOSIUM ON NEUROSCIENCE SWEDEN Hongqiang Ma, Huazhong university of science and Xin Duan, Harvard University, Cambridge, Massachusetts. Taeko Hayakawa, Keio University School of Medicine, Tokyo, technology, CHINA Yuanyuan Yao, Institute of Neuroscience, Shanghai, CHINA JAPAN Jai S. Polepalli, Stanford University School of Medicine, Palo Alto, CALIFORNIA Li-Ying OuYang, Sun Yat-Sen University, Cancer Center, Takahiro Kanamori, Osaka Bioscience Institute, Suita, JAPAN CELL SIGNALING IN METABOLISM, Guangzhou, CHINA INFLAMMATION AND CANCER Veronika Kremer, Karolinska Institutet, Stockholm, SWEDEN MEMBRANE PROTEIN STRUCTURE AND FUNCTION Ye Wang, Shanghai Institutes for Biological Sciences, CAS, Shujia Zhu, Ecole Normale Supérieure, France & ECNU, CHINA CHINA BACTERIAL INFECTION AND HOST DEFENSE Qin Yang, Harvard Medical School, USA Yiheng Hu, The Ohio State University, USA Francis Alonzo, New York University School of Medicine, USA Dan Ma,Tsinghua University, Beijing, CHINA Yuting Sun, Children's Cancer Institute Australia, AUSTRALIA Shan Li, College of Biological Sciences, Beijing, China; National Institute of Biological Sciences, Beijing, CHINA METABOLISM, OBESITY AND OBESITY-ASSOCIATED DISEASES MOLECULAR BASIS OF AGING AND DISEASE Jaclyn S. Pearson, The University of Melbourne, Melbourne, Junfeng Bi, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Enzhi Shen, NIBS, Beijing, CHINA AUSTRALIA Beijing, CHINA Mark A. McCormick, Buck Institute, USA Virginia Castiglia, Max Perutz Laboratories, University of Ju Hee Lee, Chungnam National University School of Medicine, Daejeon, SOUTH KOREA. Ziyun Wu, National University of Singapore, SINGAPORE Vienna, Vienna, AUSTRIA Kyong-Hye Joung, Research Center for Endocrine and Metabolic Diseases, Daejeon, SOUTH Kristie M. Keeney, University of British Columbia, Vancouver, KOREA CANADA FRONTIERS IN BIOINFORMATICS AND Marcela Gatica-Andrades, The University of Queensland COMPUTATIONAL BIOLOGY Diamantina Institute, Brisbane, AUSTRALIA VACCINE DESIGN Sheung Chun Ng, Hong Kong University of Science and Guan-Yu Chen, National Tsing Hua University, Hsinchu, TAIWAN Technology, HK Stephen J. Goodswen, University of Technology Sydney, Sydney, AUSTRALIA Anupama Yadav, Tata Institute of Fundamental Research, Hong You, Queensland Institute of Medical Research, Brisbane, AUSTRALIA INDIA Wenqiang Shi, Centre for Molecular Medicine and Therapeutics, CANADA

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OVERALL STATISTICS SCIENTIFIC ADVISORY BOARD 统计资料 科学顾问委员会

2013, the fourth year of Cold Spring Harbor Asia consisted with 17 conferences (7 spring conferences, 9 fall conferences HONORARY SCIENTIFIC ADVISORY BOARD and 1 oversea session in Japan) and 1 summer course. Many conferences are becoming real series meetings, which keep on repeating every 1 or 2 years, such as the membrane protein meeting, the neuro circuit meeting, etc. About 3000 scientists have joined CSH Asia’s meetings and course. Nobel laureate Dr. Thomas Sudhof attended and delivered his lecture at the Francis Crick Symposium on Neuroscience: the Changing Brain. CSH Asia is glad to have the joint conference again with ISSCR in stem cell biology and achieved a great success. CSH Asia also moved its rst step towards the oversea community and held a special CSHA session at the 86th annual meeting of the Japanese Society of Biology.

Our statistics show that there were total 2991 registrants (including 374 free auditing students and 98 representatives from the local biotech companies) from 43 countries who have participated in the seventeen meetings and the summer course. In general, female participants took about 40% of the total participants. Tadatsugu Taniguchi Zhou Guang Zhao Ministry of Health, CHINA University of Tokyo, JAPAN Chinese Association for Science & Technology, CHINA

SCIENTIFIC ADVISORY BOARD

Xuetao Cao Ann-Shyn Chiang Suzanne Cory Matthias Hentze David Ho Minoru Kanehisa Chinese Academy of National Tsing Hua Walter and Eliza Hall European Molecular Biology The Rockefeller Kyoto University, JAPAN Medical Science, CHINA University, TAIWAN Institute of Medical Laboratory, GERMANY University, USA Research, AUSTRALIA

Attendee Number by Meeting/ Course

Nancy Ip Jiayang Li Lin Li Huck-Hui Ng Yigong Shi Mandyam V. Srinivasan Hong Kong University of Chinese Academy of Shanghai Institute of Genome Institute of Tsinghua University, Queensland Brain Science & Technology, CHINA Sciences, CHINA Biological Sciences, CHINA Singapore, SINGAPORE CHINA Institute, AUSTRALIA

In terms of geographic distribution, the top 5 countries/ regions from which we have the most attendees are China (including HK) (1792), USA (503), South Korea (109), Japan (92) and Singapore (60). Bruce Stillman Junying Yuan Cold Spring Harbor Harvard University, USA Laboratory, USA

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