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Dengue–COVID-19 Coinfection: the First Reported Case in the Philippines
Case Report/Case Series Dengue–COVID-19 coinfection: the first reported case in the Philippines Angyap Saipen,a Bernard Demot,a Lowella De Leona Correspondence to Angyap Lyn Saipen (email: [email protected]) The rainy season in the Philippines is from June to October; this is when the number of dengue cases typically increases. In 2020 during this time, the world was facing the threat of severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection. Coronavirus disease 2019 (COVID-19) and dengue viral infections have similar presentations and laboratory findings, including fever and thrombocytopenia, and there have been reports of coinfection with SARS-CoV-2 and arthropod-borne virus. Here, we report a case of SARS-CoV-2–dengue virus coinfection in the Philippines in a female aged 62 years, whose early symptom was fever and who was positive for SARS-CoV-2 and positive for dengue. Early recognition of such coinfection is important so that proper measures can be taken in the management of the patient. engue fever is a mosquito-borne viral infection fever (highest recorded at 39.5 °C), with associated found mostly in tropical climates, including headache (frontoparietal in location, rated 5/10 and Dthe Philippines. The clinical manifestations of bandlike in character) and retro-orbital pain, general- dengue may include high-grade fever, headache, retro- ized body ache, myalgia and arthralgia. There was no orbital pain, muscle and joint pains, and rashes. In associated nausea, vomiting or blurring of vision. The 2019, the Philippines had one of the highest numbers patient had pain over the ankle joints, with no associ- of reported dengue cases among countries in Asia ated warmth or limitation of movement, and no rashes, and South-East Asia.1 According to the World Health cough or dyspnoea. -
VDL Annual Report
2010 Annual Report Table of Contents ISU VDL Mission Statement .......................................................................................................................... 3 VDPAM Organizational Chart ....................................................................................................................... 4 VDPAM External Advisory Board .................................................................................................................. 5 VDL Faculty List ............................................................................................................................................ 6 VDL Staff List ................................................................................................................................................ 7 New Tests Introduced ................................................................................................................................... 9 2010 Statistical Data ................................................................................................................................... 10 Accessions .............................................................................................................................................. 10 Tests ....................................................................................................................................................... 11 Submission Trends ................................................................................................................................ -
Simultaneous Pure Red Cell Aplasia and Auto-Immune Hemolytic Anemia in a Previously Healthy Infant
Simultaneous Pure Red Cell Aplasia and Auto-immune Hemolytic Anemia in a Previously Healthy Infant Robert P. Sanders, MD July 16, 2002 Case Presentation Patient Z.H. • Previously Healthy 7 month old WM • Presented to local ER 6/30 with 1 wk of decreased activity and appetite, low grade temp, 2 day h/o pallor. • Noted to have severe anemia, transferred to LeBonheur • Review of Systems – ? Single episode of dark urine – 4 yo sister diagnosed with Fifth disease 1 wk prior to onset of symptoms, cousin later also diagnosed with Fifth disease – Otherwise negative ROS •PMH – Term, no complications – Normal Newborn Screen – Hospitalized 12/01 with RSV • Medications - None • Allergies - NKDA • FH - Both parents have Hepatitis C (pt negative) • SH - Lives with Mom, 4 yo sister • Development Normal Physical Exam • 37.2 167 33 84/19 9.3kg • Gen - Alert, pale, sl yellow skin tone, NAD •HEENT -No scleral icterus • CHEST - Clear • CV - RRR, II/VI SEM at LLSB • ABD - Soft, BS+, no HSM • SKIN - No Rash • NEURO - No Focal Deficits Labs •CBC – WBC 20,400 • 58% PMN 37% Lymph 4% Mono 1 % Eo – Hgb 3.4 • MCV 75 MCHC 38.0 MCH 28.4 – Platelets 409,000 • Retic 0.5% • Smear - Sl anisocytosis, Sl hypochromia, Mod microcytes, Sl toxic granulation • G6PD Assay 16.6 U/g Hb (nl 4.6-13.5) • DAT, Broad Spectrum Positive – IgG negative – C3b, C3d weakly positive • Chemistries – Total Bili 2.0 – Uric Acid 4.8 –LDH 949 • Urinalysis Negative, Urobilinogen 0.2 • Blood and Urine cultures negative What is your differential diagnosis? Differential Diagnosis • Transient Erythroblastopenia of Childhood • Diamond-Blackfan syndrome • Underlying red cell disorder with Parvovirus induced Transient Aplastic Crisis • Immunohemolytic anemia with reticulocytopenia Hospital Course • Admitted to ICU for observation, transferred to floor 7/1. -
Aplastic Crisis Caused by Parvovirus B19 in an Adult Patient with Sickle-Cell Disease
Revista da Sociedade Brasileira de Medicina Tropical RELATO DE CASO 33(5):477-481, set-out, 2000. Aplastic crisis caused by parvovirus B19 in an adult patient with sickle-cell disease Crise aplástica por parvovírus B19 em um paciente adulto com doença falciforme Sérgio Setúbal1, Adelmo H.D. Gabriel2, Jussara P. Nascimento3 e Solange A. Oliveira1 Abstract We describe a case of aplastic crisis caused by parvovirus B19 in an adult sickle-cell patient presenting with paleness, tiredness, fainting and dyspnea. The absence of reticulocytes lead to the diagnosis. Anti-B19 IgM and IgG were detected. Reticulocytopenia in patients with hereditary hemolytic anemia suggests B19 infection. Key-words: Human parvovirus B19. Sickle-cell disease. Transient aplastic crisis. Reticulocytopenia. Resumo Descreve-se um caso de crise aplástica devida ao parvovírus B19 num paciente adulto, manifestando-se por palidez, cansaço, lipotímias e dispnéia. A ausência de reticulócitos chamou a atenção para o diagnóstico. Detectaram-se IgM e IgG anti-B19. Reticulocitopenia em pacientes com anemia hemolítica hereditária sugere infecção por B19. Palavras-chaves: Parvovírus B19. Doença falciforme. Crise aplástica transitória. Reticulocitopenia. Parvovirus B19 is the only pathogenic and the virus was labeled serum-parvovirus-like parvovirus in humans. It is a DNA virus that infects particle. Retesting the sera from their panels, which and destroys erythroid cell progenitors. Cossart and were obtained mainly from British adults, Cossart coworkers3 discovered parvovirus B19 fortuitously and coworkers demonstrated that 30% of them in 1974, when they were trying to detect HBsAg had antibodies to the virus. in panels of human sera. Unexpectedly, the serum The virus was identified again two years later numbered 19 in panel B showed an anomalous in two blood donors12, and six years later in two precipitin line in a counter immunoelectrophoresis British soldiers returning from Africa15, all of which (CIE) employing another human immune serum. -
Molecular Detection of Human Parasitic Pathogens
MOLECULAR DETECTION OF HUMAN PARASITIC PATHOGENS MOLECULAR DETECTION OF HUMAN PARASITIC PATHOGENS EDITED BY DONGYOU LIU Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2013 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20120608 International Standard Book Number-13: 978-1-4398-1243-3 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. -
This Book Is a Compendium of New Wave Posters. It Is Organized Around the Designers (At Last!)
“This book is a compendium of new wave posters. It is organized around the designers (at last!). It emphasizes the key contribution of Eastern Europe as well as Western Europe, and beyond. And it is a very timely volume, assembled with R|A|P’s usual flair, style and understanding.” –CHRISTOPHER FRAYLING, FROM THE INTRODUCTION 2 artbook.com French New Wave A Revolution in Design Edited by Tony Nourmand. Introduction by Christopher Frayling. The French New Wave of the 1950s and 1960s is one of the most important movements in the history of film. Its fresh energy and vision changed the cinematic landscape, and its style has had a seminal impact on pop culture. The poster artists tasked with selling these Nouvelle Vague films to the masses—in France and internationally—helped to create this style, and in so doing found themselves at the forefront of a revolution in art, graphic design and photography. French New Wave: A Revolution in Design celebrates explosive and groundbreaking poster art that accompanied French New Wave films like The 400 Blows (1959), Jules and Jim (1962) and The Umbrellas of Cherbourg (1964). Featuring posters from over 20 countries, the imagery is accompanied by biographies on more than 100 artists, photographers and designers involved—the first time many of those responsible for promoting and portraying this movement have been properly recognized. This publication spotlights the poster designers who worked alongside directors, cinematographers and actors to define the look of the French New Wave. Artists presented in this volume include Jean-Michel Folon, Boris Grinsson, Waldemar Świerzy, Christian Broutin, Tomasz Rumiński, Hans Hillman, Georges Allard, René Ferracci, Bruno Rehak, Zdeněk Ziegler, Miroslav Vystrcil, Peter Strausfeld, Maciej Hibner, Andrzej Krajewski, Maciej Zbikowski, Josef Vylet’al, Sandro Simeoni, Averardo Ciriello, Marcello Colizzi and many more. -
Impact of Tungiasis on School Age Children in Muranga County, Kenya
IMPACT OF TUNGIASIS ON SCHOOL AGE CHILDREN IN MURANGA COUNTY, KENYA. JOSEPHINE WANJIKU NGUNJIRI Research Thesis submitted in Fulfillment of the Requirement for the Award of a Degree of Doctor of Philosophy in Tropical and Infectious Diseases of The University of Nairobi. 2015 DECLARATION This research thesis is my original work and has not been presented for award of a degree in any other university. Josephine Wanjiku Ngunjiri Reg. No.W80/92621/2013 Signature…………………................Date…………………………… P.O Box 1881, Nyeri -Kenya The thesis has been submitted with our approval as the University supervisors. Dr. Peter N. Keiyoro Signature…………………................Date…………………………… Senior Lecturer: Biological sciences, School of continuing and Distance education University of Nairobi. P. O. Box 30197-01000, Nairobi Prof.Walter Mwanda Signature…………………................Date…………………………… Professor of Haematology : Institute of Tropical and Infectious Diseases, University of Nairobi,P. O Box 19676-00202, Kenyatta National Hospital University Campus Prof Jorg Heukelbach Signature…………………................Date…………………………… Department of Community Health, School of Medicine, Federal University of Ceará,Rua Prof. Costa Mendes 1608, 5. andar i Fortaleza CE 60430-140, Brazil ii Dedication This work is dedicated to my parents Mr.and Mrs.Ngunjiri, siblings Esther, Samuel and Teresa as well as my nephew Chris for their great support during my studies. Also to all the children in the Tungiasis endemic areas globally, this is in hope of their better future through acquisition of education. It is also hoped that these children will enjoy their childhood years free from burden of disease caused by Tungiasis. iii Acknowledgement I am grateful to the University of Nairobi Institute of Tropical and Infectious Diseases. -
A Parasitological Evaluation of Edible Insects and Their Role in the Transmission of Parasitic Diseases to Humans and Animals
RESEARCH ARTICLE A parasitological evaluation of edible insects and their role in the transmission of parasitic diseases to humans and animals 1 2 Remigiusz GaøęckiID *, Rajmund Soko ø 1 Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland, 2 Department of Parasitology and Invasive Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland a1111111111 a1111111111 * [email protected] a1111111111 a1111111111 a1111111111 Abstract From 1 January 2018 came into force Regulation (EU) 2015/2238 of the European Parlia- ment and of the Council of 25 November 2015, introducing the concept of ªnovel foodsº, including insects and their parts. One of the most commonly used species of insects are: OPEN ACCESS mealworms (Tenebrio molitor), house crickets (Acheta domesticus), cockroaches (Blatto- Citation: Gaøęcki R, SokoÂø R (2019) A dea) and migratory locusts (Locusta migrans). In this context, the unfathomable issue is the parasitological evaluation of edible insects and their role in the transmission of parasitic diseases to role of edible insects in transmitting parasitic diseases that can cause significant losses in humans and animals. PLoS ONE 14(7): e0219303. their breeding and may pose a threat to humans and animals. The aim of this study was to https://doi.org/10.1371/journal.pone.0219303 identify and evaluate the developmental forms of parasites colonizing edible insects in Editor: Pedro L. Oliveira, Universidade Federal do household farms and pet stores in Central Europe and to determine the potential risk of par- Rio de Janeiro, BRAZIL asitic infections for humans and animals. -
Copyrighted Material
Part 1 General Dermatology GENERAL DERMATOLOGY COPYRIGHTED MATERIAL Handbook of Dermatology: A Practical Manual, Second Edition. Margaret W. Mann and Daniel L. Popkin. © 2020 John Wiley & Sons Ltd. Published 2020 by John Wiley & Sons Ltd. 0004285348.INDD 1 7/31/2019 6:12:02 PM 0004285348.INDD 2 7/31/2019 6:12:02 PM COMMON WORK-UPS, SIGNS, AND MANAGEMENT Dermatologic Differential Algorithm Courtesy of Dr. Neel Patel 1. Is it a rash or growth? AND MANAGEMENT 2. If it is a rash, is it mainly epidermal, dermal, subcutaneous, or a combination? 3. If the rash is epidermal or a combination, try to define the SIGNS, COMMON WORK-UPS, characteristics of the rash. Is it mainly papulosquamous? Papulopustular? Blistering? After defining the characteristics, then think about causes of that type of rash: CITES MVA PITA: Congenital, Infections, Tumor, Endocrinologic, Solar related, Metabolic, Vascular, Allergic, Psychiatric, Latrogenic, Trauma, Autoimmune. When generating the differential, take the history and location of the rash into account. 4. If the rash is dermal or subcutaneous, then think of cells and substances that infiltrate and associated diseases (histiocytes, lymphocytes, mast cells, neutrophils, metastatic tumors, mucin, amyloid, immunoglobulin, etc.). 5. If the lesion is a growth, is it benign or malignant in appearance? Think of cells in the skin and their associated diseases (keratinocytes, fibroblasts, neurons, adipocytes, melanocytes, histiocytes, pericytes, endothelial cells, smooth muscle cells, follicular cells, sebocytes, eccrine -
Sarah C. Maza Curriculum Vitae Education: Employment
1 Sarah C. Maza Curriculum Vitae Department of History, Harris Hall Northwestern University, Evanston, Illinois, 60208-2220 Office: 847 491 7033/3406 e-mail: [email protected] Education: Princeton University, M.A.in History, 1975; Ph.D. in History, 1978 Université de Provence, Aix-en-Provence, France, Licence-ès-Lettres, 1973 Employment: Director, Nicholas D. Chabraja Center for Historical Studies, Northwestern University, 2012-2015, 2016-2019. Jane Long Professor in the Arts and Sciences, Northwestern University, 1998- Chair, Department of History, Northwestern University, 2001-2004, 2008-09; Associate Chair, 2016-17. Professor, Northwestern University, 1990- Directeur d'Études Associé, École des Hautes Études en Sciences Sociales, Paris, Spring 1988 and Spring 2011 Associate Professor, Northwestern University, 1984-1990 Assistant Professor, Northwestern University, 1978-1984 Major Prizes and Honors: Member, American Academy of Arts and Sciences, 2013- 2 President, American Society for Eighteenth-Century Studies, 2005-2006. 2004 George Mosse Prize of the American Historical Association for The Myth of the French Bourgeoisie. 1997 Chester Higby Prize of the American Historical Association for “Luxury, Morality and Social Change,” Journal of Modern History 1993 David Pinkney Prize of the Society for French Historical Studies for Private Lives and Public Affairs Grants and Fellowships: Rockefeller Center in Bellagio Writing Residency for Scholars, November 2019 Dorothy and Clarence Ver Steeg Distinguished Research Fellowship, Northwestern -
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https://www.mdc-berlin.de/de/veroeffentlichungstypen/clinical- journal-club Als gemeinsame Einrichtung von MDC und Charité fördert das Experimental and Clinical Research Center die Zusammenarbeit zwischen Grundlagenwissenschaftlern und klinischen Forschern. Hier werden neue Ansätze für Diagnose, Prävention und Therapie von Herz-Kreislauf- und Stoffwechselerkrankungen, Krebs sowie neurologischen Erkrankungen entwickelt und zeitnah am Patienten eingesetzt. Sie sind eingelanden, um uns beizutreten. Bewerben Sie sich! An otherwise healthy 10-year-old girl presented to the primary care clinic with a 10-day history of multiple itchy papules on the soles of her feet and on her toes. The lesions had black dots in the center and were painful. Two weeks earlier, the family had traveled to rural Brazil. During that time, the patient had played in a pigsty without wearing shoes. Sand fleas were removed from multiple lesions. What is the most likely diagnosis? Coxsackievirus infection Furuncular myiasis Foreign body granulomas Tungiasis Scabies infestation Correct! The correct answer is tungiasis. Tungiasis is a skin infestation caused by the sand flea Tunga penetrans, an ectoparasite that is found throughout tropical and subtropical parts of the world. Treatment included flea removal and local wound care. Die Myiasis (nach griechisch μυῖα myia = „Fliege“) oder auch Fliegenmadenkrankheit ist der Befall von Lebewesen mit den Larven (Maden) von Fliegen, welche von dem Gewebe, den Körperflüssigkeiten oder dem Darminhalt des Wirtes leben. Sie ist bei Menschen in Mittel- und Südamerika sowie in Regionen mit tropischen oder subtropischem Klima verbreitet. In der Tiermedizin kommt ein Fliegenmadenbefall auch in Europa häufiger vor. Betroffen sind vor allem stark geschwächte oder anderweitig erkrankte Tiere, die nicht mehr in der Lage sind, sich selbst zu putzen. -
Andrew J. Bacevich
ANDREW J. BACEVICH Department of International Relations Boston University 152 Bay State Road Boston, Massachusetts 02215 Telephone (617) 358-0194 email: [email protected] CURRENT POSITION Boston University Professor of History and International Relations, College of Arts & Sciences Professor, Kilachand Honors College EDUCATION Princeton University, M. A., American History, 1977; Ph.D. American Diplomatic History, 1982 United States Military Academy, West Point, B.S., 1969 FELLOWSHIPS Columbia University, George McGovern Fellow, 2014 Kroc Institute for International Peace Studies, University of Notre Dame Visiting Research Fellow, 2012 The American Academy in Berlin Berlin Prize Fellow, 2004 The Paul H. Nitze School of Advanced International Studies, Johns Hopkins University Visiting Fellow of Strategic Studies, 1992-1993 The John F. Kennedy School of Government, Harvard University National Security Fellow, 1987-1988 Council on Foreign Relations, New York International Affairs Fellow, 1984-1985 PREVIOUS APPOINTMENTS Boston University Director, Center for International Relations, 1998-2005 The Paul H. Nitze School of Advanced International Studies, Johns Hopkins University Professorial Lecturer; Executive Director, Foreign Policy Institute, 1993-1998 School of Arts and Sciences, Johns Hopkins University Professorial Lecturer, Department of Political Science, 1995-19 United States Military Academy, West Point Assistant Professor, Department of History, 1977-1980 1 PUBLICATIONS Books and Monographs Breach of Trust: How Americans Failed Their Soldiers and Their Country. New York: Metropolitan Books (2013); audio edition (2013). The Short American Century: A Postmortem. Cambridge, Massachusetts: Harvard University Press (2012). (editor) Washington Rules: America’s Path to Permanent War. New York: Metropolitan Books (2010); audio edition (2010); Chinese edition (2011); Korean edition (2013). The Limits of Power: The End of American Exceptionalism.