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Embolization of Ruptured Ovarian Granulosa Cell Tumor Presenting As Acute Hemoperitoneum
Published online: 2021-03-23 IR Snapshot Embolization of Ruptured Ovarian Granulosa Cell Tumor Presenting as Acute Hemoperitoneum A 56-year-old postmenopausal female peritoneal fluid with evidence of active Nasser Alhendi1,2, presented in shock state and abdominal contrast extravasation [Figure 1]. The exact Haitham Arabi2,3, distension. Contrast-enhanced computed origin of the mass could not be identified Raghad Alhindi1,4 tomography showed a large heterogeneous due to the presence of hemoperitoneum. 1Division of Vascular mass in the left adnexa surrounded by dense The patient was resuscitated with Interventional Radiology, Department of Medical Imaging, Ministry of National Guard‑Health Affairs, 2King Abdullah International Medical Research Center, 3Department of Pathology and Laboratory Medicine, Ministry of National Guard‑Health Affairs, 4Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia a b Figure 1: Axial pelvic contrast‑enhanced computed tomography scan in arterial phase (a) portal venous phase (b) large pedunculated heterogeneous mass arising from the uterine fundus/left adnexa, surrounded by extensive dense peritoneal fluid related to bleeding and showing internal contrast extravasation (white arrow) Address for correspondence: Dr. Nasser Alhendi, Department of Medical Imaging, Division of Vascular Interventional Radiology, King Abdulaziz Medical City, Riyadh, Saudi Arabia. E‑mail: dr_nasser1@hotmail. com Access this article online a b Website: www.arabjir.com Figure 2: Initial angiogram of left uterine artery demonstrates mildly hypertrophied distal branches (a) with focal DOI: 10.4103/AJIR.AJIR_42_18 contrast extravasation (a and b) (white arrows) Quick Response Code: This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution- NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, How to cite this article: Alhendi N, Arabi H, as long as appropriate credit is given and the new creations Alhindi R. -
Dengue–COVID-19 Coinfection: the First Reported Case in the Philippines
Case Report/Case Series Dengue–COVID-19 coinfection: the first reported case in the Philippines Angyap Saipen,a Bernard Demot,a Lowella De Leona Correspondence to Angyap Lyn Saipen (email: [email protected]) The rainy season in the Philippines is from June to October; this is when the number of dengue cases typically increases. In 2020 during this time, the world was facing the threat of severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection. Coronavirus disease 2019 (COVID-19) and dengue viral infections have similar presentations and laboratory findings, including fever and thrombocytopenia, and there have been reports of coinfection with SARS-CoV-2 and arthropod-borne virus. Here, we report a case of SARS-CoV-2–dengue virus coinfection in the Philippines in a female aged 62 years, whose early symptom was fever and who was positive for SARS-CoV-2 and positive for dengue. Early recognition of such coinfection is important so that proper measures can be taken in the management of the patient. engue fever is a mosquito-borne viral infection fever (highest recorded at 39.5 °C), with associated found mostly in tropical climates, including headache (frontoparietal in location, rated 5/10 and Dthe Philippines. The clinical manifestations of bandlike in character) and retro-orbital pain, general- dengue may include high-grade fever, headache, retro- ized body ache, myalgia and arthralgia. There was no orbital pain, muscle and joint pains, and rashes. In associated nausea, vomiting or blurring of vision. The 2019, the Philippines had one of the highest numbers patient had pain over the ankle joints, with no associ- of reported dengue cases among countries in Asia ated warmth or limitation of movement, and no rashes, and South-East Asia.1 According to the World Health cough or dyspnoea. -
VDL Annual Report
2010 Annual Report Table of Contents ISU VDL Mission Statement .......................................................................................................................... 3 VDPAM Organizational Chart ....................................................................................................................... 4 VDPAM External Advisory Board .................................................................................................................. 5 VDL Faculty List ............................................................................................................................................ 6 VDL Staff List ................................................................................................................................................ 7 New Tests Introduced ................................................................................................................................... 9 2010 Statistical Data ................................................................................................................................... 10 Accessions .............................................................................................................................................. 10 Tests ....................................................................................................................................................... 11 Submission Trends ................................................................................................................................ -
Oocyte Cryopreservation for Fertility Preservation in Postpubertal Female Children at Risk for Premature Ovarian Failure Due To
Original Study Oocyte Cryopreservation for Fertility Preservation in Postpubertal Female Children at Risk for Premature Ovarian Failure Due to Accelerated Follicle Loss in Turner Syndrome or Cancer Treatments K. Oktay MD 1,2,*, G. Bedoschi MD 1,2 1 Innovation Institute for Fertility Preservation and IVF, New York, NY 2 Laboratory of Molecular Reproduction and Fertility Preservation, Obstetrics and Gynecology, New York Medical College, Valhalla, NY abstract Objective: To preliminarily study the feasibility of oocyte cryopreservation in postpubertal girls aged between 13 and 15 years who were at risk for premature ovarian failure due to the accelerated follicle loss associated with Turner syndrome or cancer treatments. Design: Retrospective cohort and review of literature. Setting: Academic fertility preservation unit. Participants: Three girls diagnosed with Turner syndrome, 1 girl diagnosed with germ-cell tumor. and 1 girl diagnosed with lymphoblastic leukemia. Interventions: Assessment of ovarian reserve, ovarian stimulation, oocyte retrieval, in vitro maturation, and mature oocyte cryopreservation. Main Outcome Measure: Response to ovarian stimulation, number of mature oocytes cryopreserved and complications, if any. Results: Mean anti-mullerian€ hormone, baseline follical stimulating hormone, estradiol, and antral follicle counts were 1.30 Æ 0.39, 6.08 Æ 2.63, 41.39 Æ 24.68, 8.0 Æ 3.2; respectively. In Turner girls the ovarian reserve assessment indicated already diminished ovarian reserve. Ovarian stimulation and oocyte cryopreservation was successfully performed in all female children referred for fertility preser- vation. A range of 4-11 mature oocytes (mean 8.1 Æ 3.4) was cryopreserved without any complications. All girls tolerated the procedure well. -
Severe Dengue Due to Secondary Hemophagocytic Lymphohistiocytosis
IDCases 8 (2017) 50–53 Contents lists available at ScienceDirect IDCases journal homepage: www.elsevier.com/locate/idcr Case report Severe dengue due to secondary hemophagocytic lymphohistiocytosis: A case study Ujjwayini Ray*, Soma Dutta, Susovan Mondal, Syamasis Bandyopadhyay Apollo Gleneagles Hospitals, 58, Canal Circular Road, Kolkata 70054, West Bengal, India A R T I C L E I N F O A B S T R A C T Article history: Received 17 March 2017 Dengue, transmitted by the mosquito Aedes aegypti affects millions of people worldwide every year. Received in revised form 25 March 2017 Dengue induced hemophagocytic lymphohistiocytosis (HLH) is a serious condition and may prove fatal if Accepted 25 March 2017 not detected early and treated appropriately. Diagnosis of HLH is challenging and usually missed as Available online xxx clinical and laboratory findings are nonspecific. Moreover, the pathophysiology of the systemic inflammatory response syndrome and/or sepsis is remarkably similar to HLH. Secondary HLH following Keywords: infection by the dengue virus is now being increasingly recognized as a cause of severe form of the Bicytopenia disease. We report a case of dengue associated HLH in an otherwise healthy person who deteriorated Dengue during the course of hospitalization. A disproportionately high ferritin level and persistent bicytopenia Hemophagocytic lymphohistiocytosis prompted investigations for HLH. Diagnosis of dengue fever with virus-associated hemophagocytic (HLH) Infection syndrome was established according to the diagnostic criteria laid down by the Histiocyte Society. We discuss the diagnosis and management of this complex case and try to generate awareness about dengue Intravenous immunoglobulin G induced HLH as one of the possible causes for severe manifestations of this infection © 2017 The Authors. -
2014-2015 Distinction Track Program Annual Report
ACADEMIC YEAR 2014-2015 UNDERGRADUATE MEDICAL EDUCATION DISTINCTION TRACKS PROGRAM ANNUAL REPORT UNDERGRADUATE MEDICAL EDUCATION, SCHOOL OF MEDICINE M. ANN SHAW, MD, MA, FACP CHAIR, DISTINCTION TRACK ADVISING AND STEERING COMMITTEE Table of Contents Introduction ............................................................................................................................................................................ 2 Distinction Tracks Program Docket ..................................................................................................................................... 2 Individual Track Directors (Also advisory members of Distinction Track Advising and Steering Committee) ............... 2 Distinction Track Advising and Steering Committee (DTASC) Members ........................................................................ 2 Student Participants ........................................................................................................................................................ 2 Organizational Achievements ................................................................................................................................................. 3 Programatic Evaluation ........................................................................................................................................................... 4 2015 Distinction Tracks Program Graduating Student Focus Group, Summary Report ..................................................... 5 2015 Distinction Tracks -
Total Abdominal Hysterectomy (TAH)
Total Abdominal Hysterectomy (TAH) Technique Procedure involves the removal of the uterus and cervix. The decision whether or not to remove the fallopian tubes and ovaries is a separate decision. If the ovaries are removed, the procedure name includes the term bilateral salpingoophorectomy (BSO). Incisions An incision is made on the abdomen for this procedure. The size of the incision is determined by the size of your uterus and the abdominal exposure needed. The incision will either by vertical (from the belly button down to the pubic bone) or horizontal ("bikini cut"). Operative Time Operative times vary greatly depending on the findings at the time of surgery. Your surgeon will proceed with safety as his/her first priority. Average times range from 45-120 minutes. Anesthesia Spinal anesthesia or General anesthesia Preoperative Care Nothing by mouth after midnight The procedure is usually scheduled immediately after your menstrual period. Hospital Stay Inpatient stay for 2-3 days after the surgery Postoperative Care These guidelines are intended to give you a general idea of your postoperative course. Since every patient is unique and has a unique procedure, your recovery may differ. Anti-inflammatory pain medicine is usually required for the first several days to manage soreness and inflammation. Narcotic pain medicine will be provided to assist with the discomfort from the incisions. Driving is allowed after your procedure only when you do not require the narcotic pain medicine to manage your pain. Patients may return to work in 4-6 weeks following the procedure. Incisions may bruise but they should not become red or inflamed. -
THE AMERICAN JOURNAL of CANCER a Continuation of the Journal of Cancer Research
THE AMERICAN JOURNAL OF CANCER A Continuation of The Journal of Cancer Research VOLUMEXVI MAY, 1932 NUMBER3 OVARIAN NEOPLASMS W. BLAIR BELL AND M. M. DATNOW In the first part of this communication l some points in the pathology of ovarian neoplasms were discussed. Here we shall first consider certain aspects of the clinical features associated with them. These cover so large a range of connected phenomena and conditions-namely, the symptoms and physical signs in a variety of circumstances which are related to the size and position, the complications, and the biological nature of the tumour concerned- that it will be neither possible, nor indeed desirable, to present a complete study in this place. Afterwards we shall examine some general principles in regard to the treatment of these neoplasms, especially in relation to the pathological and clinical features pre- sented, and to the age and condition of the patient. I1 CLINICAL FEATURES It is somewhat difficult to collate statistical information on a scale large enough to enable us to draw definite conclusions, even in respect of the average age and parity of the patients affected, for such figures do not seem always to have interested the collectore of 1 This paper, which is a continuation of that published in an earlier number of this JOURNAL(16: 1, 1932), likewise contains the substance (amplified in regard to statistics by M. M. Datnow) of the Introduction by W. Blair Bell to the Discussion on the subject at the British Congress of Obstetrics and Gynaecology held in Glasgow on April 21, 22 and 23, 1931, for an account of which see Journal of Obstetrics and Gynaecology of the British Empire, 38: 279, 1931. -
Surgical Findings and Outcomes in Premenopausal Breast Cancer
Original Article Surgical Findings and Outcomes in Premenopausal Breast Cancer Patients Undergoing Oophorectomy: A Multicenter Review From the Society of Gynecologic Surgeons Fellows Pelvic Research Network Lara F. B. Harvey, MD, MPH, Vandana G. Abramson, MD, Jimena Alvarez, MD, Christopher DeStephano, MD, MPH, Hye-Chun Hur, MD, Katherine Lee, MD, Patricia Mattingly, MD, Beau Park, MD, Carolyn Piszczek, MD, Farinaz Seifi, MD, Mallory Stuparich, MD, and Amanda Yunker, DO, MSCR From the Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee (Drs. Harvey and Yunker), Division of Hematology/Oncology, Vanderbilt Ingram Cancer Center, Nashville, Tennessee (Dr. Abramson), Department of Obstetrics and Gynecology, Advocate Lutheran General Hospital, Park Ridge, Illinois (Dr. Alvarez), Department of Medical and Surgical Gynecology, Mayo Clinic, Jacksonville, Florida (Dr. DeStephano), Division of Minimally Invasive Gynecology, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts (Dr. Hur), Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana (Dr. Lee), Division of Gynecologic Specialty Surgery, Department of Obstetrics and Gynecology, Columbia University Medical Center, New York-Presbyterian Hospital, New York, New York (Dr. Mattingly), Department of Obstetrics and Gynecology, Mayo Clinic Arizona, Phoenix, Arizona (Dr. Park), Division of Gynecologic -
Flavivirus Cross-Reactivity to Dengue Nonstructural Protein 1 Antigen Detection Assays
diagnostics Article Flavivirus Cross-Reactivity to Dengue Nonstructural Protein 1 Antigen Detection Assays Li Kiang Tan 1, Wing Yan Wong 1, Hui Ting Yang 1, Roland G. Huber 2 , Peter J. Bond 2,3, Lee Ching Ng 1,4, Sebastian Maurer-Stroh 2,3 and Hapuarachchige Chanditha Hapuarachchi 1,* 1 Environmental Health Institute, National Environment Agency, Singapore 38667, Singapore; [email protected] (L.K.T.); [email protected] (W.Y.W.); [email protected] (H.T.Y.); [email protected] (L.C.N.) 2 Bioinformatics Institute, Agency for Science, Technology and Research, Singapore 138671, Singapore; [email protected] (R.G.H.); [email protected] (P.J.B.); [email protected] (S.M.-S.) 3 Department of Biological Sciences, National University of Singapore, Singapore 117558, Singapore 4 School of Biological Sciences, Nanyang Technological University, Singapore 639798, Singapore * Correspondence: [email protected]; Tel.: +65-65115335; Fax: +65-65115339 Received: 7 November 2019; Accepted: 23 December 2019; Published: 24 December 2019 Abstract: Dengue virus (DENV) and Zika virus (ZIKV) are flaviviruses of public health relevance. Both viruses circulate in the same endemic settings and acute infections generally manifest similar symptoms. This highlights the importance of accurate diagnosis for clinical management and outbreak control. One of the commonly used acute diagnostic markers for flaviviruses is nonstructural protein 1 (NS1). However, false positives due to antigenic cross-reactivity have been reported between DENV and ZIKV infections when using DENV NS1 antigen (NS1 Ag) detection assays in acute cases. Therefore, we investigated the lowest detectable virus titres and cross-reactivity of three commercial dengue NS1 Ag rapid assays and two ELISAs for different flaviviruses. -
Endocrine Abstracts Vol 62
Endocrine Abstracts April 2019 Volume 62 ISSN 1479-6848 (online) Society for Endocrinology Endocrine Update 2019 published by Online version available at bioscientifi ca www.endocrine-abstracts.org Volume 62 Endocrine Abstracts April 2019 Society for Endocrinology: Endocrine Update 2019 08–10 April 2019 Programme Chairs: Dr James Ahlquist (Essex) Dr Peter Taylor (Cardiff) Abstract Markers: Dr Simon Aylwin (London) Dr Kristien Boelaert (Birmingham) Dr Karin Bradley (Bristol) Dr Andrew Lansdown (Cardiff) Dr Daniel Morganstein (London) Dr Helen Turner (Oxford) Professor Bijay Vaidya (Exeter) Dr Nicola Zammitt (Lasswade) Society for Endocrinology: Endocrine Update 2019 CONTENTS Society for Endocrinology: Endocrine Update 2019 NATIONAL CLINICAL CASES Oral Communications . ...................................... OC1–OC10 Poster Presentations . ....................................... P01–P73 CLINICAL UPDATE Workshop A: Disorders of the hypothalamus and pituitary . WA1–WA11 Workshop B: Disorders of growth and development . WB1–WB3 Workshop C: Disorders of the thyroid gland ..................................... WC1–WC10 Workshop D: Disorders of the adrenal gland ..................................... WD1–WD16 Workshop E: Disorders of the gonads . ..................................... WE1–WE10 Workshop F: Disorders of the parathyroid glands, calcium metabolism and bone . WF1–WF3 Workshop G: Disorders of appetite and weight . WG1–WG2 Workshop H: Miscellaneous endocrine and metabolic disorders . WH1–WH9 Additional Cases . ..................................... -
Detection of NS1 Antigen in Serologically Confirmed Dengue Cases at Least After 5 Days of Infection
Research Article Anatomy Physiol Biochem Int J Volume 4 Issue 2- February 2018 Copyright © All rights are reserved by Sudipta Poddar DOI: 10.19080/APBIJ.2017.04.555632 Detection of NS1 Antigen in Serologically Confirmed Dengue Cases at least after 5 Days of Infection Sudipta Poddar* and Amiya Kumar Hati Department of Medical Physiology, Lincoln University College, Malaysia Submission: January 01, 2017; Published: February 09, 2018 *Corresponding author: Sudipta Poddar, Department of Medical Physiology, Lincoln University College, 47301, Petaling Jaya, Malaysia; Email: Abstract Objectives: The objective of this paper is to detect the NS1 antigen beyond 5 days of infection in serologically confirmed dengue cases in whom both NS1 antigen and IgG and IgM antibodies were assessed. Methods: Out of a total of 1037 suspected persons 257 i.e. 24.78% were dengue reactive in 2013 and 2014. Dengue cases were diagnosed in the laboratory from suspected patients by dengue specific IgG, IgM antibodies and NS1 antigen. NS1 antigen and IgG antibodies were monitored in 220 (194+26) suspected dengue cases where interpretation was possible to detect NS1 beyond 5 days of infection. This study of detection of NS1 antigen in serologically confirmed dengue cases at least after 5 days of infection. Results: Among this 220 cases 86 (80+6) were confirmed dengue cases. Out of these 86 cases NS1 antigen was found beyond 5 days of infection in 15 i.e. 17.44%. Conclusion: It would be reasonable to believe that many such cases would be found in the category I where only NS1 was tested. Hence for getting the information on NS1 antigen beyond 5 days all three serological tests (NS1 antigen, IgG and IgM antibodies) should be performed.