Workshop Workshop 1： Cell structure / Cell polarity / Cytoskeleton / Cell Motility (1) DATE: June 6 (Wed) 16:30-19:00 Room B Chairpersons: Takashi Murata (NIBB) Akihito Inoko (Aichi Cancer Center Research Institute) WS01-01 16:30-16:42 Cilia-related structure regulates the differentiation and maturation of T cells in thymus ○Osamu Kutomi, Sen Takeda (Grad. Sch. Med., Univ. Yamanashi) WS01-02 16:42-16:54 Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway ○Yoshishige Kimura 1,2, Koji Tsutsumi2 , Alu Konno 2, Koji Ikeg- ami2 , Saira Hameed2 , Tomomi Kaneko1 , Oktay Ismail Kaplan3 , Takayuki Teramoto4 , Manabi Fujiwara4 , Takeshi Ishihara4 , Oliver E. Blacque3 , Mitsutoshi Setou 2 (Department of Liberal Arts and Sciences, Kanagawa University of Human Services1 , Department of Cellular & Molecular Anatomy, Hamamatsu University School of Medicine2 , School of Biomolecular and Biomedical Science, University College Dublin3 , Department of Biology, Faculty of Sciences, Kyushu University4 ) WS01-03 16:54-17:06 Albatross/FBF1 integrates centrosome dynamics (P2-097) ○ Akihito Inoko1 , Tomoki Yano2 , Tatsuo Miyamoto3 , Shinya Mat- suura 3 , Tohru Kiyono 4 , Naoki Goshima 5 , Masaki Inagaki1 , Yuko Hayashi1 ( Division of Biochemistry, Aichi Cancer Center Research Institute1 , Laboratory of Biological Science, Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University2 , Department of Genetics and Cell Biology, Research Institute for Radiation Biology and Medicine, Hiro- shima University 3, Division of Carcinogenesis and Cancer Pre- vention, National Cancer Center Research Institute4 , Molecular Profi ling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology5 ) WS01-04 17:06-17:18 Super-resolution imaging of primary cilia by expansion (P2-108) microscopy ○ Yohei Katoh1 , Shuhei Chiba2 , Kazuhisa Nakayama1 (Grad. Sch.

64 of Pharm. Sci., Univ.1 , Grad. Sch. of Med., Osaka City Univ.2 ) WS01-05 17:18-17:30 Single actin fi laments observation revealed that Latrun- (P2-126) culin A depolymerizes actin filaments in addition to sequestering actin monomers ○ Ikuko Fujiwara1 , Mark E. Zweifel2 , Naomi Courtemanche2 , Thomas D. Pollard3 (Frontier Research Institute for Materials Science, Institute of Technology, Gokiso, Showa-ku, Nagoya, 466-8555, Japan1 , Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA 2 , Department of Molecular Cellular and Develop- mental Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103 USA 3 ) WS01-06 17:30-17:42 Novel mechanism of regulation of microtubule dynam- ics by EB2/RP1 microtubule binding protein ○ Maiko Higuchi1 , Keisuke Onishi2 , Yukiko Gotoh3 (Rikkyo Uni- versity1 , University of California, San Diego2 , University of Tokyo3 ) WS01-07 17:42-17:54 Helical rotation of mDia1 untwists and stabilizes actin fi laments against cofi lin Hiroaki Mizuno1 , Kotaro Tanaka3 , Sawako Yamashiro1 , Akihiro Narita3 , ○ Naoki Watanabe1,2 (Kyoto Univ. Grad. Sch. Biostudies1 , Kyoto Univ. Grad. Sch. Medicine 2 , Nagoya Univ. Structural Biol- ogy Research Center3 ) WS01-08 17:54-18:06 Cdc42-FMNL3 mediated constitutive actin regrowth (P1-070) underneath plasma membrane underlies the repetitive nature of membrane blebs ○Kana Aoki 1, Shinsuke Satoi 1, Seiichi Uchida3 , Yoh Iwasa 2 , Junichi Ikenouchi2,4 (Grad. Sch. Systems Life Sciences, Kyushu University1 , Dept. Biol, Kyushu University2 , Dept. Advanced Information technology, Kyushu University3 , AMED-PRIME, Agency for Medical Research and Development4 ) WS01-09 18:06-18:18 Mechanism of Catalytic Microtubule Depolymerization (P2-099) via KIF2-tubulin Transitional Conformation ○ Tadayuki Ogawa1 , Shinya Saijo2 , Nobutaka Shimizu2 , Xuguang Jiang 1 , Nobutaka Hirokawa 1 (Department of Cell Biology and Anatomy, University of , Graduate School of Medicine1 , Photon Factory, Institute of Materials Structure Science, High

65 Energy Accelerator Research Organization2 ) WS01-10 18:18-18:30 Super-resolution live imaging of supercellular circum- (P1-085) ferential actin cable formation during tracheal tubulo- genesis ○ Sayaka Sekine, Mustafa Sami, Housei Wada, Shigeo Hayashi (RIKEN Center for Biosystems Dynamics Research) WS01-11 18:30-18:42 Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling. ○Koji Kikuchi 1, Akira Nakamura 2, Masaki Arata 3, Dongbo Shi 4 , Mami Nakagawa4 , Tsubasa Tanaka2 , Tadashi Uemura3 , Toshihiko Fujimori4 , Akira Kikuchi5 , Akiyoshi Uezu1 , Yasuhisa Sakamoto1 , Hiroyuki Nakanishi1 (Dept. Mol. Pharm., Grad. Sch. of Med. Sci., Univ.1 , Dept. Germline Dev., IMEG, Kumamoto Univ.2 , Grad. Sch. of Biostudies, Kyoto Univ.3 , Div. of Embryol- ogy, NIBB 4 , Dept. Mol. Biol. and Biochem., Grad. Sch. Med., Osaka Univ.5 ) WS01-12 18:42-18:54 Cell stiff ness is critical for germ cell migration in avian embryo ○ Daisuke Saito (FRIS, Tohoku University) Workshop 2：Cell Proliferation / Apoptosis / Signal transduc- tion DATE: June 6 (Wed) 16:30-19:00 Room C Chairpersons: Hisataka Sabe (Hokkaido Univ.) Shizue Ohsawa (Kyoto Univ.) WS02-01 16:30-16:42 Notch signaling dynamics for the asymmetric cell fate determination in the mouse neurogenesis ○ Shun Mase1,2 , Yuji Tsunekawa1 , Atsunori Shitamukai1 , Fumio Matsuzaki1,2 (Laboratory for Cell Asymmetry, RIKEN BDR, JAPAN 1, Graduate School of Biostudies, Kyoto University, JAPAN 2 ) WS02-02 16:42-16:54 Ribonucleotide threshold to induce p53 damage pathway (P1-026) during embryonic development in mouse ○Ryo Uehara, Naushaba Hasin, Kiran Sakhuja, Susana M Cer- ritelli, Robert J Crouch (Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health)

66 WS02-03 16:54-17:06 PLEKHN1 promotes apoptosis by enhancing Bax/Bak (P2-027) hetero-oligomerization through the interaction with Bid in human colon cancer ○ Sei Kuriyama (Akita University) WS02-04 17:06-17:18 The cell-type specific functions of an ER modulating (P2-036) factor, Pecanex in Notch and Wnt signaling pathways ○ Tomoko Yamakawa, Kenji Matsuno (Osaka University) WS02-05 17:18-17:30 ER-resident BH3-only protein, BNip1, is a safe guard (P2-040) that limits the upper threshold of vesicular transport ○ Yuko Nishiwaki, Kimberlie Ward, Ichiro Masai (Okinawa Insti- tute of Science and Technology) WS02-06 17:30-17:42 Snail interacts with FoxO to modulate JNK-dependent (P2-025) cell death in Drosophila ○Chenxi Wu1,2 (College of Chinese Medicine, North China Uni- versity of Science and Technology, China1 , School of Life Sci- ence and Technology, Tongji University, China2 ) WS02-07 17:42-17:54 Multiplexed live cell imaging reveals a distinct role of (P2-033) ERK and Akt activity in cell cycle progression. ○ Gembu Maryu1,3 , Michiyuki Matsuda1,2 , Kazuhiro Aoki3 (Gradu- ate school of Biostudies, Kyoto University1 , Graduate School of Medicine, Kyoto University2 , Division of Quantitative Biology, National Institute of Basic Biology3 ) WS02-08 17:54-18:06 Caspase drives Drosophila wing growth independent of (P1-027) apoptosis to ensure the bilateral symmetry of wing size ○ Natsuki Shinoda1 , Takahiro Chihara2 , Akiko Koto1 , Masayuki Miura1 (The Univ. of Tokyo1 , Hiroshima Univ.2 ) WS02-09 18:06-18:18 Composite regulation of ERK activity dynamics under- (P2-042) lying tumor-specifi c traits in the intestine ○ Masamichi Imajo1 , Yu Muta2,3 , Michiyuki Matsuda1,3 (Lab. Bio- imag. Cell Signal., Grad. Sch. of Biostud., Kyoto Univ.1 , Dept. Gastroenterol. Hepatol., Grad. Sch. of Med., Kyoto Univ.2 , Dept. Pathol. Biol. Dis., Grad. Sch. of Med., Kyoto Univ.3 ) WS02-10 18:18-18:30 The Yorkie/YAP and Ras-driven tumorigenesis via FoxO target microRNA-mediated inhibition of cellular senes- cence ○ Takao Ito, Masato Enomoto, Tatsushi Igaki (Kyoto University) WS02-11 18:30-18:42 Crosstalk between JNK and p38 kinase generates cell-to- (P2-029)

67 cell variation in JNK activity dynamics and determines a cell fate decision ○ Haruko Miura1,2 , Michiyuki Matsuda2,3 , Kazuhiro Aoki1,4 (Div. Quant. Biol., OIIB, NIBB, NINS 1 , Lab. Bioimaging Cell Signal., Grad. Sch. Biostudies, Kyoto Univ. 2 , Dept. Pathol. Biol. Dis., Grad. Sch. Med., Kyoto Univ.3 , Dept. Basic Biol., Sch. Life Sci., SOKENDAI 4 ) WS02-12 18:42-18:54 Cell-to-cell propagation of JNK signaling controls tissue repair and regeneration ○ Masato Enomoto, Tatsushi Igaki (Lab. of Genet., Grad. Sch. of Bio, Kyoto Univ.)

Workshop 3： Life of proteins / Intracellular trafficking / Organelles (1) DATE: June 6 (Wed) 16:30-19:00 Room D Chairpersons: Mitsunori Fukuda (Tohoku Univ.) Tetsuro Izumi (Gunma Univ.) WS03-01 16:30-16:42 Regulation mechanism of the phosphatidylserine flip- (P2-087) pase ATP11C Hiroyuki Takatsu, Masahiro Takayama, Kazuhisa Nakayama, ○ Hye-Won Shin (Graduate School of Pharmaceutical Sciences, Kyoto University) WS03-02 16:42-16:54 Phosphorylation of TANGO1 regulates localization and (P2-057) function of ER exit sites ○ Miharu Maeda1 , Toshiaki Katada2 , Kota Saito1 (Dept. of Biol. Informatics and Experimental Therapeut., Grad. Sch. of Medi- cine, Akita Univ.1 , Faculty of Pharmacy, Musashino Univ.2 ) WS03-03 16:54-17:06 Endosomal Q-SNARE Syntaxin 7 specifi es a subpopula- (P2-059) tion of recycling synaptic vesicles preferentially respon- sive to high frequency stimulation ○ Yasunori Mori1 , Yugo Fukazawa2 , Shigeo Takamori1 (Doshisha Univ.1 , Fukui Univ.2 ) WS03-04 17:06-17:18 Crag/Rab10/Ehbp1 regulate basolateral transport of (P1-047) Na + K + ATPase in Drosophila photoreceptors ○Yuka Ochi, Yuri Nakamura, Takunori Satoh, Akiko K. Satoh (Division of Life Science, Graduate School of Integral Arts and Science, Hiroshima University)

68 WS03-05 17:18-17:30 Arf1p and Rab11 play key roles in Rab5 activation in Saccharomyces cerevisiae ○ Makoto Nagano1 , Junko Y. Toshima1,2 , Jiro Toshima1 (Dept. of Bio. Sci. and Tech., Tokyo Univ. of Sci. 1, Dept. of Phys. Ther., Tokyo Univ. of Tech.2 ) WS03-06 17:30-17:42 Synapse Elimination Triggered by BMP4 Exocytosis (P1-058) and Presynaptic BMP Receptor Activation ○ Takahito Higashi, Shinji Tanaka, Tadatsune Iida, Shigeo Okabe (Tokyo Univ. Schol of Medicine) WS03-07 17:42-17:54 Regulation of localization and function of syntaxin 17 (P2-079) by 14-3-3 epsilon Kengo Yoshinaga1 , Kohei Arasaki1 , Naoshi Dohmae2 , ○Mitsuo Tagaya1 (Tokyo Univ. of Pharm. & Life Sci.1 , RIKEN CSRS 2 ) WS03-08 17:54-18:06 T r a ffi cking of ciliary GPCRs mediated by the BBSome (P1-048) depends on its interaction with the IFT-B complex ○Shohei Nozaki, Yohei Katoh, Kazuhisa Nakayama (Graduate School of Pharmaceutical Sciences, Kyoto University) WS03-09 18:06-18:18 The conserved Cep57-pericentrin module organizes (P1-030) PCM expansion and centriole engagement ○ Koki Watanabe, Daiju Kitagawa (National Institute of Genetics) WS03-10 18:18-18:30 Ca2+ Signaling Response after Mechanical Stimulation of (P1-029) Single Immotile Cilium in Mammalian Node. ○Takanobu A Katoh1 , Katsutoshi Mizuno2 , Hiroshi Hamada2 , Takayuki Nishizaka1 (Department of Physics, Gakushuin Univer- sity1 , Center for Developmental Biology, Riken2 ) WS03-11 18:30-18:42 Involvement of actin dynamics in the endocytic process (P2-091) revealed by fast-scanning atomic force microscopy ○ Aiko Yoshida1 , Nobuaki Sakai3 , Yoshitsugu Uekusa3 , Shige H Yoshimura2 , Yusuke Ohba 1 (Univ. of Hokkaido1 , Kyoto Univ.2 , Olympus Co. 3 ) WS03-12 18:42-18:54 Exophilin-8/MyRIP/Slac2C assembles secretory gran- (P2-069) ules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa ○Kohichi Matsunaga1 , Fushun Fan1 , Hao Wang1 , Ray Ishizaki1 , Eri Kobayashi1 , Hiroshi Kiyonari 3 , Yoshiko Mukumoto 3 , Katsuhide Okunishi1 , Tetsuro Izumi1,2 (Laboratory of Molecular Endocrinology and Metabolism, Department of Molecular Medi-

69 cine, Institute for Molecular and Cellular Regulation1 , Research Program for Signal Transduction, Division of Endocrinology, Metabolism and Signal Research, Gunma University Initiative for Advanced Research2 , Animal Resource Development Unit, and Genetic Engineering Team, RIKEN Center for Life Science Technologies3 )

Workshop 4：Cell adhesion / ECM / Cell-cell interaction / Mechanobiology (1) DATE: June 6 (Wed) 16:30-19:00 Room E Chairpersons: Noriyuki Kioka (Kyoto Univ.) Hiroshi Sasaki (Osaka Univ.) WS04-01 16:30-16:42 The noise-cancelling system supporting precise Wnt/ (P3-006) β-catenin signaling-mediated vertebrate tissue patterning ○ Yuki Akieda, Shohei Ogamino, Hironobu Furuie, Shizuka Ishi- tani, Tohru Ishitani (Lab of Integ Signal Sys, Dept of Mol Med, IMCR, Gunma Univ.) WS04-02 16:42-16:54 Plasma membrane of cell-ECM adhesion region pos- (P1-089) sesses lipid raft-like lipid composition. ○ Kodai Minoura 1 , Takafumi Ichikawa1 , Tomohiro Ohmachi1 , Ya suhisa Kimura1 , Kazumitu Ueda1,2 , Noriyuki Kioka1 (Div. of App. Life Sci., Grad. Sch. of Agriculture, Kyoto Univ.1 , iCeMS, Kyoto Univ. 2 ) WS04-03 16:54-17:06 Integrin adhesions mediate and are shaped by the cross- talk between microtubule and the actomyosin cytoskele- ton ○Yukako Nishimura1 , Nisha Bte Mohd Rafiq1,3 , Sergey V Plot- nikov2 , Zhen Zhang1 , Visalatchi Thiagarajan1 , Meenubharathi Natarajan1 , Gareth E Jones3 , Pakorn Kanchanawong1,4 , Alexander D Bershadsky 1,5 (MBI, NUS 1 , Dept. of Cell and Syst. Biol., Univ. of Toronto2 , Randall Div. of Cell and Mol. Biophys., KCL3 , Dept. of Biomed. Eng., NUS4 , Dept. of Mol. Cell Biol., WIS5 ) WS04-04 17:06-17:18 The epithelial circumferential actin belt regulates YAP/ TAZ through nucleocytoplasmic shuttling of Merlin ○ Kana Furukawa Tamura1 , Kazunari Yamashita2 , Shigeo Ohno 1 (Dept. of Mol. Cell Biol., Grad Sch. of Med., Yokohama City Univ.1 , Dept. of Mol. Cell Biol., Grad. Sch. of Life Sci., Tohoku Univ.2 )

70 WS04-05 17:18-17:30 Iterative relay of epidermal growth factor receptor sig- (P1-092) naling regulates epithelial invagination via a wave of cellular contractility ○Yosuke Ogura1 , Fu-Lai Wen2 , Mustafa M. Sami1 , Tatsuo Shi- bata2 , Shigeo Hayashi1 (Laboratory for Morphogenetic Signaling, RIKEN Center for Biosystems Dynamics Research 1, Laboratory for Physical Biology, RIKEN Center for Biosystems Dynamics Research2 ) WS04-06 17:30-17:42 ERK activation waves mediated by intercellular (P1-095) mechanical signaling during collective cell migration ○ Naoya Hino1,2 , Michiyuki Matsuda1,3 , Tsuyoshi Hirashima 3 (Lab. of Bioimaging and Cell Signaling, Grad. Sch. of Biostudies, Kyoto Univ. 1 , JSPS Research Fellow 2 , Dept. of Path. and Biol. of Diseases, Grad. Sch. of Med., Kyoto Univ. 3 ) WS04-07 17:42-17:54 The role of MAP kinase pathway in response to mechan- (P3-015) ical force during Xenopus embryogenesis ○Noriyuki Kinoshita 1, Yutaka Hashimoto 1,2, Cristea M Ileana2 , Naoto Ueno1 (Dept. of Dev. Biol., NIBB1 , Dept. of Mol. Biol. Princeton Univ.2 ) WS04-08 17:54-18:06 Alpha-catenin controls the anisotropy of force distribu- tion at cell-cell junctions during collective cell migration ○ Kenji Matsuzawa, Takuya Himoto, Yuki Mochizuki, Junichi Ikenouchi (Kyushu University Department of Cell Biology) WS04-09 18:06-18:18 Force-dependent arrest of keratinocyte proliferation and its potential defect in skin cancer ○ Hiroaki Hirata1,2 , Atsushi Enomoto3 , Masaki Sunagawa3 , Oleg Dobrokhotov 1,2 , Masahide Takahashi3 , Mikhail Samsonov4 , Masa- hiro Sokabe1 (Mechanobiology Laboratory, Nagoya University Graduate School of Medicine1 , R-Pharm Japan 2 , Department of Pathology, Nagoya University Graduate School of Medicine3 , R-Pharm4 ) WS04-10 18:18-18:30 Mechanotransduction of mesenchymal stem cells pro- motes mammary cancer growth via prosaposin secretion. ○ Seiichiro Ishihara1 , Suzanne M Ponik2 , David R Inman2 , Wan-Ju Li3 , Hisashi Haga1 , Patricia J Keely2 (Dept. Advanced Transdisci- plinary Sciences, Fac. Advanced Life Science, Hokkaido Univ.1 , Dept. Cell and Regenerative Biology, Univ. of Wisconsin-Madi- son 2 , Dept. Orthopedics and Rehabilitation & Biomedical Engi-

71 neering, Univ. of Wisconsin-Madison3 ) WS04-11 18:30-18:42 Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation ○ Hironobu Fujiwara 1 , Chun-Chun Cheng 1 , Ko Tsutsui 1 , Toru Taguchi2 , Noriko Sanzen1 , Asako Nakagawa 1 , Kisa Kakiguchi1 , Shigenobu Yonemura3 , Chiharu Tanegashima4 , Sean Keeley4 , Hiroshi Kiyonari4 , Yasuhiro Furuta4 , Yasuko Tomono5 , Fiona Watt6 (RIKEN Center for Developmental Biology1 , Niigata Uni- versity of Health and Welfare2 , Tokushima Univ.3 , RIKEN Center for Life Science Technologies4 , Shigei Medical Research Inst.5 , King’s College London6 ) WS04-12 18:42-18:54 Cyclical Local Compression on Skeletal Muscle Modu- lates Macrophage Function and Alleviates Immobiliza- tion-Induced Atrophy ○ Kumiko Saitou 1,2 , Masakuni Tokunaga 2 , Takahiro Maekawa2 , Daisuke Yoshino5 , Ryu Youngjae2 , Motoshi Nagao2 , Noriaki Kawanishi6 , Katsuhiko Suzuki8 , Toru Ogata2 , Michiru Makuuchi3 , Atsushi Takashima4 , Yoshinori Ichihara7 , Yasuhiro Sawada2 (Graduate School of Sport Sciences, Waseda University1 , Depart- ment of Rehabilitation for Motor Function, Research Institute, National Rehabilitation Center for Persons with Disabilities2 , Section of Neuropsychology, Research Institute, National Reha- bilitation Center for Persons with Disabilities3 , Department of Assistive Technology, Research Institute, National Rehabilitation Center for Persons with Disabilities4 , Division, Frontier Research Institute for Interdisciplinary Sciences, Tohoku Creative Interdis- ciplinary Research University5 , Faculty of Advanced Engineer- ing, Chiba Institute of Technology6 , Department of Pathophysio- logical and Therapeutic Science, Faculty of Medicine, Tottori University7 , Faculty of Sport Sciences, Waseda University8 )

Workshop 5： Tissue / Organogenesis /Morphogenesis (1) DATE: June 6 (Wed) 16:30-19:00 Room F Chairpersons: Kenji Matsuno (Osaka Univ.) Mitsuru Morimoto (RIKEN BDR) WS05-01 16:30-16:42 Quantitative analysis of cellular and tissue dynamics during early heart morphogenesis ○ Yoshihiro Morishita, Naofumi Kawahira, Naoki Kida, Ken-ichi

72 Hironaka, Daisuke Ohtsuka (RIKEN Quantitative Biology Cen- ter) WS05-02 16:42-16:54 A novel 3D morphologic change of epithelial cells, cell twisting, may account for left-right directional tissue rotation ○ Mikiko Inaki1 , Akino Okubo1 , Takamichi Sushida2 , Masakazu Akiyama2 , Yasuhiro Inoue3 , Kenji Matsuno1 (Osaka Univ., Grad. Sch. Sci., Dept. Biol. Sci.1 , Hokkaido Univ., RIES2 , Kyoto Univ., IFLMS 3 ) WS05-03 16:54-17:06 Id protein regulates MyosinID and MyosinIC balance via YAP independent Hippo pathway to control the left- right asymmetric development of the Drosophila hindgut ○Tomoki Ishibashi, Ryo Hatori, Yoko Matsuyama, Kenji Mat- suno (Osaka University) WS05-04 17:06-17:18 Involvement of heparan sulfate in the regulation of (P1-124) Nodal signaling range in Xenopus for the generation of left-right asymmetry ○ Takafumi Ikeda, Takayoshi Yamamoto, Masanori Taira (Dept. of Biol. Scis., Grad. Sch. of Sci., Univ. of Tokyo) WS05-05 17:18-17:30 Two types of heparan sulfate diff erently modulates BMP (P3-051) distribution and signalling ○Takayoshi Yamamoto1,2 , Yusuke Mii3 , Yuta Otsuka1 , Masanori Taira1 (Dept. of Biol. Scis., Grad. Sch. of Sci., Univ. of Tokyo1 , Dept. of Life Scis., Grad. Sch. of Arts and Scis., Univ. of Tokyo2 , National Institute for Basic Biology3 ) WS05-06 17:30-17:42 3D Cell behavior in zebrafi sh somite morphogenesis (P1-109) ○ Yue Tong1 , Harunobu Kametani1 , Atsuko Shimada 1 , Masakazu Akiyama2 , Yasuhiro Inoue3 , Hiroyuki Takeda1 (Dept. of Biol. Sci., Univ. of Tokyo1 , RIES, Hokkaido Univ.2 , IFLMS, Kyoto Univ. 3 ) WS05-07 17:42-17:54 Noise-Resistant Developmental Reproducibility in Ver- (P3-022) tebrate Somite Formation ○ Naoki Honda1 , Dini WK Sari2 , Ryutaro Akiyama2 , Shin Ishii1 , Yasumasa Bessho2 , Takaaki Matsui2 (Kyoto University1 , Nara Institute of Science and Technology2 ) WS05-08 17:54-18:06 Resynchronization dynamics of the zebrafi sh segmenta- (P3-053) tion clock ○ Koichiro Uriu (Kanazawa University)

73 WS05-09 18:06-18:18 Physical characteristics of epithelium during limb mor- (P1-134) phogenesis ○ Kazuki Kawamura1 , Makoto Ono1 , Atsushi Kuroiwa 1 , Yoshihiro Morishita2 , Takayuki Suzuki1 (Nagoya University1 , Quantitative Biology Center2 ) WS05-10 18:18-18:30 Epidermal regulation of bone patterning through the (P3-030) development and regeneration of osteoblasts in the zebrafi sh scale Miki Iwasaki1 , Junpei Kuroda2 , Koichi Kawakami3 , ○ Hironori Wada1 (Kitasato University 1 , Osaka University 2, National Institute of Genetics; SOKENDAI 3 ) WS05-11 18:30-18:42 Roles of a transcription factor 19A in the osteoblast (P1-123) development of sternum ○Mao Kuriki1 , Fuminori Sato1 , Kenta Sumiyama2 , Koichi Kawakami3 , Atsuko Sehara-Fujisawa 1 ( I FLMS., Univ of Kyoto 1 , RIKEN 2 , NIG 3 ) WS05-12 18:42-18:54 Fine tuning of ocular FGF activity regulates diff erentia- tion and collective movement of lens fi bre cells ○Yuki Sugiyama1,2 , John W McAvoy 2, Ichiro Masai1 (Okinawa Inst. of Sci. Tech., OIST1 , Save Sight Inst., Univ. of Sydney2 )

Workshop 6： Cell structure / Cell polarity / Cytoskeleton / Cell Motility (2) DATE: June 7 (Thu) 9:00-11:00 Room A Chairpersons: Naoyuki Inagaki (NAIST) Atsushi Suzuki (Hiroshima Univ.) WS06-01 0 9:00-09:12 Jaw1/LRMP has a role in maintaining nuclear shape via (P1-080) interaction with SUN proteins ○Takuma Kozono1 , Kazuko Tadahira2 , Wataru Okumura1 , Nao Itai2 , Miwa Tamura-Nakano3 , Taeko Dohi4 , Takashi Tonozuka2 , Atsushi Nishikawa1,2 (Department of Food and Energy Systems Science, Graduate School of Bio-Applications Systems Engineer- ing, Tokyo University of Agriculture and Technology1 , Division of Applied Biological Chemistry, United Graduate School of Agricultural Science, Tokyo University of Agriculture and Tech- nology2 , Communal Laboratory, Research Institute, National Center for Global Health and Medicine3 , Department of Gastro-

74 enterology, Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Health and Medi- cine4 ) WS06-02 09:12-09:24 Shootin1b is involved in chemosensing and mechano- (P2-142) sensing of migrating dendritic cells ○ Kentarou Baba, Mizuki Sakai, Yasuna Higashiguchi, Naoyuki Inagaki (Graduate School of Biological Sciences, Nara Institute of Science and Technology) WS06-03 09:24-09:36 Highly Oriented actin fi bers aff ect the nuclear morphol- ogy during early stage of osteogenic differentiation of mesenchymal stem cell ○ Masashi Yamazaki1,2 , Shota Iwakura1 , Manabu Numao1,2 , Hiromichi Fujie1 , Hiromi Miyoshi1,2 (Faculty of System design, Tokyo Metropolitan University1 , AMED, PRIME 2 ) WS06-04 09:36-09:48 The yeast centriole-less centrosome reveals an ancestral (P1-083) role for the pericentrin in centriole biogenesis and integ- rity ○ Daisuke Ito, Monica Bettencourt-Dias (Instituto Gulbenkian de Ciencia) WS06-05 09:48-10:00 A novel link between ploidy level and centrosome (P1-068) homeostasis in human somatic cells ○ Kan Yaguchi, Takahiro Yamamoto, Ryota Uehara (Grad. Sch. of Life Sci., Hokkaido Univ.) WS06-06 10:00-10:12 Exploring the molecular pathways leading to bipolar (P1-067) spindle formation ○ Takashi Toda, Masaki Okazaki, Tomoaki Yamauchi, Yusuke Yamada, Tomoki Kawakami, Yasuhiro Teratani, Mitsuki Oishi, Masashi Yukawa (Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University) WS06-07 10:12-10:24 KIF2A regulates the development of dentate granule (P2-101) cells and postnatal hippocampal wiring ○ Noriko Homma1,2 , Ruyun Zhou2,4 , Muhammad Imran Naseer3 , Adeel G Chaudhary 3 , Mohammed H Al-Qahtani 3 , Nobutaka Hirokawa2,3 (National College of Nursing1 , Graduate School of Medicine, University of Tokyo2 , Center of Excellence in Genomic Medicine Research, King Abdula University3 , Jichi Medical School4 )

75 WS06-08 10:24-10:36 MTCL2 is a new member of microtubule-crosslinking (P2-130) proteins Masateru Miki, Sonoko Mizuno, Tomoko Satake, ○ Atsushi Suzuki (Yokohama City Univ. Graduate school of Medical Life Science) WS06-09 10:36-10:48 Cytoplasmic streaming controls organelle positioning (P2-122) during the oocyte-to-embryo transition in the C. elegans zygote ○Kenji Kimura1 , Akatsuki Kimura1,2 (Cell Arch. Lab., Natl. Inst. of Genet.1 , Dept. of Genet., SOKENDAI 2 ) WS06-10 10:48-11:00 Altered PI(4)P generation by mutations in INPP5K, a phosphoinositide phosphatase, gene identified in indi- vidual exhibiting congenital muscular dystrophy ○Takeshi Ijuin, Tadaomi Takenawa ( Univeristy Graduate School of Medicine)

Workshop 7： Tissue / Organogenesis /Morphogenesis (2) DATE: June 7 (Thu) 9:00-11:00 Room B Chairpersons: Tsuyoshi Hirashima (Kyoto Univ.) Makoto Suzuki (NIBB) WS07-01 0 9:00-09:12 Synchronized mesenchymal cell polarization and diff er- entiation shape the trachea ○ Keishi Kishimoto1 , Masaru Tamura2 , Mayo Shigeta3 , Takaya Abe 3,4 , Michiru Nishita5 , Yasuhiro Minami5 , Mi tsuru Morimoto 1 (Laboratory for Lung Development, Riken CDB1 , Technology and development team for mouse phenotype analyses, Riken BRC2 , Animal Resource Development Unit, Riken CLST3 , Genetic Engineering Team, Riken CLST4 , Department of Physi- ology and Cell biology, Kobe University5 ) WS07-02 09:12-09:24 The dynamic epithelial transition of developing trachea (P1-115) unveiled by single cell RNA-seq ○ Hirofumi Kiyokawa, Mitsuru Morimoto (Riken CDB) WS07-03 09:24-09:36 Possible roles of hyaluronan signaling in stem cell niche formation during intestinal remodeling in Xenopus laevis ○Kenta Fujimoto1 , Takashi Hasebe1 , Mitsuko Kajita2 , Atsuko Ishizuya-Oka1 (Dept. of Biol., Nippon Med. Sch.1 , Dept. of Mol. Oncol., Inst. for Adv. Med. Sci., Nippon Med. Sch.2 )

76 WS07-04 09:36-09:48 SOX2-dependent determination of tissue identities in the (P3-026) foregut ○ Machiko Teramoto1 , Ryo Sugawara1 , Atsushi Kuroiwa 2 , Yasuo Ishii3 , Hisato Kondoh1 (Faculty of Life Sciences, Kyoto Sangyo University1 , Division of Biological Science, Graduate School of Science, Nagoya University2 , Department of Biology, School of Medicine, Tokyo Women’s Medical University3 ) WS07-05 09:48-10:00 Twisting movement of plant leaf: Genetic analysis and (P1-108) 3D observation ○ Yuta Otsuka 1 , Ken Haga 2 , Tatsuya Sakai3 , Hirokazu Tsukaya 1,4 (Grad. Sch. Sci., Univ. Tokyo1 , Dept. Hum. Sci. Com. Edu., NIT2 , Grad. Sch. Sci. Tech., Niigata Univ.3 , OIIB, NINS 4 ) . WS07-06 10:00-10:12 A positive transcriptional feedback coordinates tissue architecture with cell fate during tubulogenesis ○Takefumi Kondo1,2 , Shigeo Hayashi3 (Grad. Sch. of Biostudies, Kyoto Univ.1 , K-CONNEX 2 , RIKEN CDB 3 ) WS07-07 10:12-10:24 Control of whole body shape by a single constituent of (P3-027) the apical ECM in Drosophila melanogaster ○Reiko Tajiri, Haruhiko Fujiwara, Tetsuya Kojima (Graduate School of Frontier Sciences, the University of Tokyo) WS07-08 10:24-10:36 Oscillatory cortical forces promote three dimensional cell intercalations that shape the mandibular arch ○ Hirotaka Tao1 , Min Zhu 1,2, Kimberly Lau 1 , Owen K.W. Whitley 1 , Mohammad Samani1 , Xiao Xiao 1 , Xiao Xiao Chen 1 , Noah A. Hahn 1,2, Weifan Liu1,2 , Kelli D. Fenelon1,2 , Clarissa C. Pasiliao1,2 , Shoshana Spring1,2 , R. Mark Henkelman1,2 , Alexander Dunn3 , Huaxiong Huang 4, Hsin-Yi Henry Ho 5, Radhika Atit6 , Sidhartha Goyal2 , Yu Sun 2, Sevan Hopyan 1,2,7 (The Hospital for Sick Chil- dren1 , University of Toronto2 , Stanford University3 , York Univer- sity4 , University of California5 , Case Western Reserve Univer- sity 6 , Division of Orthopaedic Surgery, Hospital for Sick Children7 ) WS07-09 10:36-10:48 Keratan sulfate produces “water bags” in embryos (P3-036) ○ Yuuri Yasuoka (Marine Genomics Unit, OIST) WS07-10 10:48-11:00 Src-transformed cells hijack mitosis to extrude from the epithelium Katarzyna Anton1 , Mihoko Kajita2 , Rika Narumi2 , Yasuyuki Fujita2 , ○ Masazumi Tada1 (University College London1 , Hok-

77 kaido University2 )

Workshop 8： Diff erentiation / Regeneration / Stem cells (1)

DATE: June 7 (Thu) 9:00-11:00 Room C Chairpersons: Kenta Terai (Kyoto Univ.) Takeshi Inoue (Gakushuin Univ.) WS08-01 09:00-09:12 Intravital imaging reveals a role of ERK activity in (P1-150) migration of myoblasts during muscle regeneration. ○Yumi Konagaya 1, Michiyuki Matsuda 1,2 , Kenta Terai1 ( L a b o r a - tory of Bioimaging and Cell Signaling Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan 1 , Department of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606- 8501, Japan2 ) WS08-02 09:12-09:24 Induction of regeneration responses in chicken limb bud by exogenous Fgf application ○ Akira Satoh, Aki Makanae (Okayama Univ.) WS08-03 09:24-09:36 Core transcription factors promote induction from human iPS cells of functional Pax3-positive skeletal muscle stem cells ○ Takahiko Sato1 , Koki Higashioka2 , Chie Sotozono1 (Kyoto Pre- fectural University of Medicine1 , Doshisha University2 ) WS08-04 09:36-09:48 Positional information DOES exit within cells of a single (P3-080) fi n ray during zebrafi sh regeneration ○ Atsushi Kawakami, Eri Shibata (Tokyo Inst. Technology) WS08-05 09:48-10:00 TRAF6-mediated NF-kB is essential for the diff erentia- (P3-094) tion of intestinal M cells ○ Takashi Kanaya1 , Sayuri Sakakibara1 , Toshiro Sato2 , Takashi Kobayashi3 , Hiroshi Ohno 1 (Laboratory for Intestinal ecosystem, RIKEN-IMS 1 , Department of Gastroenterology, Keio Univ.2 , Department of Infectious Diseases Control, Faculty of Medicine, Oita Univ.3 ) WS08-06 10:00-10:12 Aberration of the Soluble protein Tsukushi leads altera- (P3-071) tion of adult neurogenesis resulting lateral ventricule expansion with neuronal disease. ○Naofumi Ito1,2,3 , M. Asrafuzzaman Riyadh 1,3, Ayako Ito 1, Shah

78 Adil Ishtiyaq Ahmad1,2,3,4 , Mohammad Badrul Anam1,2,3 , Yonehiro Kanemura5,6 , Yohei Shinmyo7 , Felemban Athary Abdulhaleem M. 1,9 , Jun Hatakeyama10 , Hiroshi Kiyonari 11 , Kenji Shimamura10 , Yoshiko Takahashi12,13 , Kazunobu Sawamoto14,8 , Kunimasa Ohta1,2,3,13 (Department of Developmental Neurobiology, Graduate School of Life Sciences, Kumamoto University1 , Program for Leading Graduate Schools “HIGO Program”, Kumamoto Univer- sity 2 , Stem Cell-Based Tissue Regeneration Research and Educa- tion Unit, Kumamoto University3 , Department of Biotechnology and Genetic Engineering, Mawlana Bhashani Science and Tech- nology University, Tangail, Bangladesh4 , Division of Regenera- tive Medicine, Institute for Clinical Research5 , Department of Neurosurgery, Osaka National Hospital, National Hospital Orga- nization6 , Department of Medical Neuroscience, Graduate School of Medical Sciences, Kanazawa University7 , Department of Developmental and Regenerative Biology, Nagoya City Univer- sity Graduate School of Medical Sciences8 , Department of Biol- ogy, Faculty of Applied Science, Umm Al-Qura University, 21955, Makkah, Saudi Arabia.9 , Department of Brain Morpho- genesis, Institute of Molecular Embryology and Genetics, Kuma- moto University10 , Animal Resource Development Unit and 12Genetic Engineering Team, RIKEN Center for Life Science Technology11 , Department of Zoology, Graduate School of Sci- ence, Kyoto University.12 , AMED Core Research for Evolutional Science and Technology (AMED-CREST), Japan Agency for Medical Research and Development (AMED).13 , Division of Neural Development and Regeneration, National Institute for Physiological Sciences.14 ) WS08-07 10:12-10:24 Roles of lysosomes in embryonic neural stem/progenitor (P1-137) cells ○ Naoya Yuizumi, Yujin Harada, Daichi Kawaguchi, Shohei Furu- tachi, Yukiko Gotoh (Lab. of Molecular Biology, Department of Pharmaceutical Sciences, The Univ. of Tokyo) WS08-08 10:24-10:36 Causal link between epimorphin and E-cadherin in regu- (P1-143) lation of keratinocyte diff erentiation ○ Noriko Tachibana, Yohei Hirai (Department of Biomedical Chemistry, Graduate School of Science and Technology, Kwansei Gakuin University)

79 WS08-09 10:36-10:48 Cytological and transcriptomic analyses on adventitious (P1-154) bud formation from the epidermis in cultured stem seg- ments of Torenia fournieri . ○ Hatsune Morinaka1 , Akihito Mamiya1 , Akitoshi Iwamoto2 , Hiroaki Tamaki1 , Takamasa Suzuki3 , Yoshikatsu Sato4 , Momoko Ikeuchi5 , Akira Iwase 5, Keiko Sugimoto5 , Tetsuya Higashiyama4 , Munetaka Sugiyama1 (Univ. Tokyo1 , Tokyo Gakugei Univ.2 , Chubu Univ.3 , Nagoya Univ.4 , Riken5 ) WS08-10 10:48-11:00 Coordinated regulation of the dorsal-ventral and anterior- (P3-069) posterior patterning of Xenopus embryos by the BTB/ POZ zinc fi nger protein Zbtb14 Kimiko Takebayashi-Suzuki, Misa Uchida, ○ Atsushi Suzuki (Amphibian Research Center, Hiroshima University) Workshop 9： Technical advances (genome editing, imaging, bioinformatics, etc.) DATE: June 7 (Thu) 9:00-11:00 Room D Chairperson: Yasushi Okada (RIKEN BDR) Kazuhiro Aoki (NIBB) WS09-01 09:00-09:12 Mimicking human gastrulation stage using human iPS cells ○ Kiyoshi Ohnuma (Nagaoka University of Technology) WS09-02 09:12-09:24 Depletion of autophagy receptor p62/SQSTM1 enhances (P3-149) the effi ciency of gene delivery in mammalian cells ○Hidesato Ogawa 1, Megumi Tsuchiya1 , Takako Koujin2 , Chie Mori2 , Hiroko Osakada2 , Shouhei Kobayashi2 , Ya sushi Hiraoka 2,1 , Tokuko Haraguchi1,2 (Osaka Univ.1 , NICT2 ) WS09-03 09:24-09:36 Quantitative control of mitochondria transfer between (P3-139) live single cells using a microfluidic device toward mtDNA editing ○ Ken-Ichi Wada, Kazuo Hosokawa, Yoshihiro Ito, Mizuo Maeda (RIKEN) WS09-04 09:36-09:48 A novel genome-integrating vector system for cell and (P1-171) developmental biology studies ○Takuma Kumamoto1 , Raphaëlle Barry1 , Samuel Tozer1 , Franck Maurinot1 , Célia Vaslin2 , Mickaël Le1 , Stephane Nedelec2 , Karine Loulier1 , Jean Livet1 (Sorbonne Université, INSERM, CNRS,

80 Institut de la Vision1 , Sorbonne Université, INSERM, Institut du Fer à Moulin2 ) WS09-05 09:48-10:00 Measurement of caveolin-1 densities in the cell mem- (P3-143) brane for quantification of caveolar deformation after exposure to hypotonic membrane tension Masashi Tachikawa2 , ○ Shiro Suetsugu1 (Nara Institute of Science and Technology1 , Theoretical Biology Laboratory, RIKEN2 ) WS09-06 10:00-10:12 Optical measurement of neuronal activity in zebrafish (P1-174) brain by genetically encoded voltage indicators ○Kanoko Okumura1 , Hiroaki Miyazawa1 , Kanae Hiyoshi1 , Kazuhiro Maruyama1 , Hisaya Kakinuma2 , Ryunosuke Amo 2 , Hitoshi Okamoto2 , Kyo Yamasu1 , Sachiko Tsuda1,3 (Graduate School of Science and Engineering, Saitama University1 , Riken Brain Science Institute2 , Research and Development Bureau, Saitama University3 ) WS09-07 10:12-10:24 Imaging of the single molecular behavior of transcrip- tional factors in living pluripotent stem cells ○Kazuko Okamoto1 , Kohei Yamamura2,3 , Yasushi Okada 2,4,3 , Tomonobu M Watanabe1 (RIKEN Center for Biosystems Dynam- ics Research, Comprehensive bioimaging Lab.1 , RIKEN Center for Biosystems Dynamics Research, Lab. for Cell Polarity Regu- lation2 , Dep. FBS, Osaka University 3 , School of Science, the Uni- versity of Tokyo4 ) WS09-08 10:24-10:36 Optical control of cell signaling by the genetically- (P3-138) encoded PhyB-PIF system ○Youichi Uda1,2 , Michiyuki Matsuda1,3 , Kazuhiro Aoki2 ( D epart- ment of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University1 , Division of Quantitative Biology, Okazaki Institute for Integrative Bioschence, National Institute for Basic Biology, National Institutes of Natural Sciences2 , Labo- ratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University3 ) WS09-09 10:36-10:48 Partially hydrated and markedly destructured hydrogen- (P3-144) bond network of intracellular water investigated with terahertz spectroscopy ○Keiichiro Shiraga1 , Takeshi Matsui1 , Mika Sawada2 , Shojiro Kikuchi2 , Tetsuhito Suzuki3 , Takeshi Mitsunaka4 , Masafumi Yamanoue4 , Yuichi Ogawa3 (RIKEN Center for Integrative Medi-

81 cal Sciences1 , Institute for Advanced Medical Science, Hyogo College of Medicine2 , Graduate School of Agriculture, Kyoto University3 , Electronic Components and Devices BU., Sharp Corporation4 ) WS09-10 10:48-11:00 Non-labeled cancer cell analysis in anhydrous condition (P1-172) using CMOS biosensor integrated circuit (IC) with 20/60/120-GHz oscillator arrays ○ Shojiro Kikuchi1 , Mika Sawada 1 , Tetsuhito Suzuki2 , Keiichiro Shiraga3 , Takeshi Matsui3 , Takeshi Mitsunaka4 , Masafumi Yama- noue4 , Yuichi Ogawa2 (Institute for Advanced Medical Science, Hyogo College of Medicine1 , Graduate School of Agriculture, Kyoto University2 , RIKEN Center for Integrative Medical Sci- ences3 , Sharp Corporation, Electronic Components and Devices BU 4 )

Workshop 10： Chromosome / Nucleus / Gene expression / Epi- genetics / Genomics & Life of proteins / Intracel- lular traffi cking / Organelles (2)

DATE: June 7 (Thu) 9:00-11:00 Room E Chairperson: Kozo Tanaka (Tohoku Univ.) Hajime Ogino (Hiroshima Univ.) WS10-01 09:00-09:12 How to measure absolute quantity of tRNAs. (P2-009) Akihisa Nagai, Kouhei Mori, Yuma Shiomi, ○ Tohru Yoshihisa (Graduate School of Life Science, University of Hyogo) WS10-02 09:12-09:24 Cooperative control of molting and metamorphosis through steroid hormone biosynthesis by transcription and splicing factors in Drosophila ○Takumi Kamiyama1 , Outa Uryu 2, Tatsuya Komura-Kawa1 , Naoki Tani3 , Yuko Shimada-Niwa4 , Akira Nakamura5 , Ryusuke Niwa6,7 (Graduate School of Life and Environmental Sciences, University of Tsukuba, 305-8572, Ibaraki, Japan1 , Department of Applied Biological Sciences, Saga University, Honjo-machi 1, Saga 840-8502, Japan2 , Liaison Laboratory Research Promotion Center, Institute of Molecular Embryology and Genetics Kuma- moto University, Kumamoto 860-0811, Japan3 , Life Science Cen- ter of Tsukuba Advanced Research Alliance, University of Tsu- kuba, Tsukuba, 305-8572, Japan 4, Department of Germline Development, Division of Organogenesis, Institute of Molecular

82 Embryology and Genetics, Kumamoto University 2-2-1 Honjo, Kumamoto 860-0811, Japan5 , Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, 305-8572, Japan 6 , PRESTO, Japan Science and Technology Agency, 102-0076, Japan7 ) WS10-03 09:24-09:36 Molecular basis of kinetochore recruitment of the RZZ (P2-003) complex and its roles in the establishment of bi-orienta- tion during mitosis in human cells ○ Masanori Ikeda, Kozo Tanaka (Department of Molecular Oncol- ogy, Institute of Development, Aging and Cancer, Tohoku Uni- versity) WS10-04 09:36-09:48 The role of Crm1, a nuclear export receptor, in the regu- lation of gene expression ○ Masahiro Oka 1 , Sonoko Mura 2 , Yoichi Miyamoto1 , Yasuyuki Ohkawa3 , Hiroshi Kimura4 , Yoshihiro Yoneda1 (NIBIOHN 1 , Osaka Univ. 2 , Kyushu Univ. 3 , Tokyo Inst. of Tech.4 ) WS10-05 09:48-10:00 ‘Anti-model’ biology assisted by whole genome analysis of sharks and reptiles ○ Shigehiro Kuraku (RIKEN Center for Biosystems Dynamics Research) WS10-06 10:00-10:12 No temporal collinearity is evident for de novo transcrip- tion of Hox cluster genes in Xenopus tropicalis whole embryos ○ Mariko Kondo1 , Megumi Matsuo1 , Kento Igarashi1 , Yoshikazu Haramoto2 , Takayoshi Yamamoto1 , Yuuri Yasuoka 3 , Masanori Taira1 (Univ. of Tokyo1 , AIST 2 , OIST 3 ) WS10-07 10:12-10:24 Quantification and manipulation of fission yeast cell cycle by single cell imaging ○ Yuhei Goto, Kazuhiro Aoki (National Institute for Basic Biol- ogy) WS10-08 10:24-10:36 The CLIP–cohibin system promotes nucleophagy after (P2-076) TORC1 inactivation in yeast Golam Md. Mostofa, Arifur Muhammad Rahman, ○ Takashi Ushimaru (Graduate School of Science and Technology, Shi- zuoka University) WS10-09 10:36-10:48 Analysis of the proteoglycan pathway of the mammalian (P2-086) Golgi stress response that regulates the transcription of

83 glycosylation enzymes for proteoglycans ○Mai Taniguchi, Ryota Komori, Chiho Okuda, Ryuya Tanaka, Kanae Sasaki, Sadao Wakabayashi, Hiderou Yoshida (University of Hyogo) WS10-10 10:48-11:00 Regulation of yorkie gene expression through its own non-coding region ○ Hideki Yoshida1 , Takanari Umegawachi1 , Hiromu Koshida1 , Momoko Yamada1 , Yasuyuki Ohkawa2 , Te tsuya Sato2 , Mikita Suyama2 , Henry M Krause 3, Masamitsu Yamaguchi1 (Kyoto Insti- tute of Technology1 , Kyushu University 2 , Univesity of Toronto3 ) Workshop 11： Fertilization / Gametogenesis / Reproduction & Diff erentiation / Regeneration / Stem cells (2) DATE: June 7 (Thu) 9:00-11:00 Room F Chairperson: Akira Nakamura (Kumamoto Univ.) Daisuke Saito (Tohoku Univ.) WS11-01 09:00-09:12 Protein phosphatase 2A (PP2A) is essential for mainte- nance of meiotic arrest in the larvacean, Oikopleura dio- ica ○Masaki Matsuo, Takeshi A. Onuma, Hiroki Nishida (Lab of Developmental Biology, Osaka Univ) WS11-02 09:12-09:24 Blockage of sperm Ca2+ -permeable channels involves the (P2-019) maintenance of its quality for fertilization in the newt, Cynops pyrrhogaster . ○Akihiko Watanabe1 , Eriko Takayama-Watanabe2 , Nanae Makino1 (Biol. Div., Fac. of Sci., Yamagata Univ.1 , Inst. of Arts and Sci., Yamagata Univ.2 ) WS11-03 09:24-09:36 T o explore the feminizing genes mediated by SMAD4 in (P1-016) germ cell ○Ryuki Shimada, Yumiko Saga (Division of Mammalian Devel- opment, NIG) WS11-04 09:36-09:48 RSK-MASTL pathway delays meiotic exit in mouse (P2-016) zygotes to ensure paternal chromosome stability ○Shou Soeda1,2 , Kaori Yamada-Nomoto3 , Miho Ohsugi 2 (Okinawa Institute of Science and Technology1 , Graduate School of Arts and Sciences, The University of Tokyo2 , Faculty of Medicine, Toyama University3 )

84 WS11-05 09:48-10:00 Identifi cation of a new maternal factor involved in germ (P2-017) cell formation in the Drosophila embryos Takashi Yoshitani1,2,4 , Hirono Kina 1,2,4, Tsubasa Tanaka1,2,3 , Kazuko Hanyu-Nakamura1 , ○ Akira Nakamura1,2,3 (Institute of Molecular Embryology and Genetics, Kumamoto University1 , School of Pharmacy, Kumamoto University2 , Graduate School of Pharma- ceutical Sciences, Kumamoto University3 , Equal contribution4 ) WS11-06 10:00-10:12 Regulatory mechanisms and biological significance of (P2-015) metabolic shift in mouse primordial germ cell develop- ment ○ Yohei Hayashi1,2,3 , Keiko Tanaka1,4 , Kei Otsuka1 , Masayuki Ebina5,6 , Kaori Igarashi7 , Asuka Takehara1 , Mitsuyo Matsumoto5,8 , Akio Kanai7 , Kazuhiko Igarashi3,5,8 , Tomoyoshi Soga7 , Yasuhisa Matsui1,2,3,8 (Cell Resource Center for Biomedical Research, Insti- tute of Development, Aging and Cancer (IDAC), Tohoku Univer- sity1 , Graduate School of Life Sciences, Tohoku University2 , The Japan Agency for Medical Research and Development-Core Research for Evolutional Science and Technology (AMED- CREST)3 , Department of Obstetrics and Gynecology, Tohoku University Hospital 4 , Department of Biochemistry, Tohoku Uni- versity School of Medicine5 , Department of Integrative Genom- ics, Tohoku Medical Megabank Organization (ToMMO), Tohoku University School of Medicine6 , Institute for Advanced Biosci- ences, Keio University7 , Center for Regulatory Epigenome and Diseases, Tohoku University School of Medicine8 ) WS11-07 10:12-10:24 Impact of temperature conditions on mouse spermato- (P1-011) genesis revealed by testicular organ culture ○Kodai Hirano1,2 , Yuta Nonami1,2 , Yoshiaki Nakamura1,2 , Takuya Sato3,4 , Takehiko Ogawa3,4 , Shosei Yoshida1,2 (Division of Germ Cell Biology, National Institute for Basic Biology, National Insti- tutes of Natural Sciences1 , Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (SOKENDAI) 2 , Laboratory of Proteomics, Institute of Molecular Medicine and Life Science, Yokohama City University Associa- tion of Medical Science3 , Department of Urology, Yokohama City University Graduate School of Medicine4 ) WS11-08 10:24-10:36 A novel STRA8 interacting factor, MEIOSIN1, directs initiation of meiosis in mammals ○ Kei-ichiro Ishiguro (Institute of Molecular Embryology and

85 Genetics, Kumamoto University) WS11-09 10:36-10:48 Tead-Yap activity in inner cell mass promotes naïve plu- (P3-079) ripotency and its variation triggers cell competition to establish high quality epiblast ○ Masakazu Hashimoto, Yusuke Takenoshita, Yuki Yuri, Hiroshi Sasaki (Osaka University) WS11-10 10:48-11:00 Making chimera with non-rodent PSCs by overexpress- (P3-081) ing BCL2 ○ Hideki Masaki1 , Tomoyuki Yamaguchi1 , Hiromitsu Nakauchi1,2 (Institute of Medical Science, University of Tokyo1 , Institute for Stem Cell Biology and Regenerative Medicine, Department of Genetics, Stanford University School of Medicine, Stanford2 )

Workshop 12： Cell structure / Cell polarity / Cytoskeleton / Cell Motility (3) DATE: June 8 (Fri) 9:00-11:00 Room A Chairperson: Tatsuo Shibata (RIKEN BDR) Fumio Motegi (TLL, MBI, NUS) WS12-01 09:00-09:12 Direction of calcium waves is linked with the left-right axis of larvacean embryos ○Takeshi A Onuma, Hiroki Nishida (Division of Biological Sci- ences, Graduate School of Science, Osaka University) WS12-02 09:12-09:24 Self-organization of actin fi laments of the same polarity (P2-136) by myosin Kohei Yoshimura1 , Nobuyoshi Koie1 , Yuichi Hiratsuka 2 , ○ Kohji Ito1 (Chiba University1 , JAIST 2 ) WS12-03 09:24-09:36 The dynamic self-patterning of Plk4 regulates centriole (P1-079) duplication. ○ Shohei Yamamoto, Daiju Kitagawa (The University of Tokyo) WS12-04 09:36-09:48 Diff erential polarity - an effi cient and rapid mechanism of cell sorting ○Taihei Fujimori1 , Akihiko Nakajima1,2 , Satoshi Sawai1,2 (Grad. Sch. of Arts & Sci., Univ. of Tokyo 1 , Res. Cent. for Complex Syst. Biol., Univ. of Tokyo2 ) WS12-05 09:48-10:00 A cell-size dependent polarity mechanism revealed by (P2-129) high-throughput imaging analysis of migrating cells

86 ○ Akihiko Nakajima1 , Motohiko Ishida2 , Ayaka Matsumoto3 , Satoshi Sawai1,2 (Research Center for Complex Systems Biology, the University of Tokyo1 , Graduate School of Arts and Sciences, the University of Tokyo2 , Faculty of Science, the University of Tokyo3 ) WS12-06 10:00-10:12 Development of the RNAi screening system for apico- basal polarity factors ○Shozo Honda 1, Isao Naguro 2, Shigenobu Yonemura 1,3 (Depart- ment of Cell Biology, Tokushima University Graduate School of Biomedical Sciences1 , Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo2 , Ultrastructural Research Laboratory, Riken CLST3 ) WS12-07 10:12-10:24 Gamma-tubulin ring complex-specific components are (P2-141) required for nuclear positioning in the C. elegans gonad ○Nami Haruta, Chihiro Uchiyama, Asako Sugimoto (Grad. Sch. Life Sci., Tohoku University) WS12-08 10:24-10:36 Chirality in the dynamic behavior of blood cell cyto- plasm in Drosophila ○Takeshi Sasamura1 , Daisuke Kurisu 1, Masakazu Akiyama2 , Kohei Otomo2 , Kaname Nemoto2 , Hiroaki Mizuno3 , Naoki Wata- nabe3 , Kenji Matsuno1 (Grad. Sch. of Sci., Osaka Univ.1 , RIES, Hokkaido Univ. 2 , Grad. Sch. of Med., Kyoto Univ.3 ) WS12-09 10:36-10:48 Dynamics of the Par complex clusters during the cell- (P1-082) autonomous polarization and asymmetric division in the reconstruction system ○Kalyn Kawamoto1,2 , Shigeki Yoshiura2 , Fumio Matsuzaki1,2 (Grad. Sch. of Bio., Kyoto University1 , RIKEN CDB 2 ) WS12-10 10:48-11:00 Polarity-dependent folding of epithelial sheets in three dimensions ○ FuLai Wen, YuChiun Wang, Tatsuo Shibata (RIKEN Center for Biosystems Dynamics Research)

87 Workshop 13： Tissue / Organogenesis /Morphogenesis (3) & Diff erentiation / Regeneration / Stem cells (3) DATE: June 8 (Fri) 9:00-11:00 Room B Chairperson: Shinji Takada (ExCELLS, NINS) Jun Motoyama (Doshisha Univ.) WS13-01 09:00-09:12 Role of axonal transport of Reelin in layer and neural (P3-037) circuit formation in the cerebellum and the optic tectum Takayuki Nimura1 , Takuto Hayashi1 , Miki Takeuchi2 , Tsubasa Itoh1 , Vincenzo Di Donata3 , Filippo Del Bene3 , Takashi Shi- mizu1,2 , ○ Masahiko Hibi1,2 (Graduate School of Science, Nagoya University 1 , Bioscience and Biotechnology Center, Nagoya Uni- versity2 , Institut Curie3 ) WS13-02 09:12-09:24 Synaptic transmission from subplate neurons controls radial migration of neocortical neurons ○ Chiaki Ohtaka-Maruyama1 , Mayumi Okamoto2 , Kentaro Endo1 , Minori Oshima3 , Noe Kaneko1,3 , Kei Yura3,4 , Haruo Okado 1 , Takaki Miyata2 , Nobuaki Maeda1 ( T okyo Metropol. Inst. Med. Sci.1 , Nagoya Univ. Grad. Sch. Med. 2 , Ochanomizu Univ.3 , Waseda Univ.4 ) WS13-03 09:24-09:36 Quantitative analysis of tissue and cellular dynamics (P3-033) during optic vesicle formation ○ Daisuke Ohtsuka, Yoshihiro Morishita (RIKEN Quantitative Biology Center) WS13-04 09:36-09:48 Roof plate cells dramatically elongate and promote the (P3-046) proliferation of neural progenitors by secreting Wnt pro- teins in the mouse spinal cord ○ Takuma Shinozuka1,2,3 , Ritsuko Takada1,2 , Shosei Yoshida 2,3 , Shigenobu Yonemura4,5 , Shinji Takada1,2,3 (OIIB 1 , NIBB 2 , SO KENDAI 3 , RIKEN CLST4 , Tokushima Univ.5 ) WS13-05 09:48-10:00 Live imaging of node graft and host cells to establish its role in head development Koya Yoshihi 1 , Kagayaki Kato2 , ○ Hisato Kondoh 1 (Kyoto Sangyo University1 , National Institute for Basic Biology2 ) WS13-06 10:00-10:12 Differential adhesion of N-cadherin in columnar unit (P3-032) organization in the Drosophila brain ○ Makoto Sato, Olena Trush, Chuyan Liu (Kanazawa University)

88 WS13-07 10:12-10:24 A Screening for the new regulatory pathway of the fl oor (P3-028) plate diff erentiation ○Minori Kadoya, Noriaki Sasai (Nara Institute of Science and Technology) WS13-08 10:24-10:36 Region-specifi c requirement of fl oor plate-derived sonic (P3-090) hedgehog regulating specification of the ventral cell fates ○ Jun Motoyama (Doshisha University) WS13-09 10:36-10:48 A heat-shock mediated multi-color labeling of the (P3-074) enteric neural crest cells for analyzing the patterns of their migration, division and diff erentiation in zebrafi sh gut. Mai Kuwata 1 , ○Masataka Nikaido1 , Koichi Kawakami2 , Kohei Hatta1 (Grad. Sch. of Life Sciences, Univ. of Hyogo1 , Div. of Molecular and Developmental Biology, National Institute of Genetics2 ) WS13-10 10:48-11:00 Elucidation of the expansion-to-neurogenic phase transi- (P1-152) tion in neocortical neural progenitor cells ○ Naohiro Kuwayama, Yusuke Kishi, Yurie Nishiumi, Yukiko Gotoh (Faculty of pharmaceutical science, The university of Tokyo)

Workshop 14：Life of proteins / Intracellular trafficking / Organelles (3) DATE: June 8 (Fri) 9:00-11:00 Room C Chairperson: Shinichi Hisanaga (TMU) Takeshi Noda (Osaka Univ.) WS14-01 09:00-09:12 Identifi cation of cAMP-dependent protein kinase A as a (P2-089) novel selective substrate for autophagy ○Yoshitaka Kurikawa 1, Koji L. Ode 2, Hiroki R. Ueda 2,3, Noboru Mizushima1 (Dept. of Mol. Biol., Grad. Sch. of Med, Univ. of Tokyo1 , Dept. of Sys. Pharm., Grad. Sch. of Med, Univ. of Tokyo2 , QBiC, RIKEN 3 ) WS14-02 09:12-09:24 Tag1 is involved in termination of autophagy in yeast Shintaro Kira1 , Masafumi Noguchi2 , ○Takeshi Noda1,2 (Osaka University Grad Scl Dentistry1 , Osaka University Grad Scl Fron- tier Bio Science2 )

89 WS14-03 09:24-09:36 Autophagosome-ER contact visualized by a novel ER- (P1-064) phagy receptor ○ Haruka Chino1,2 , Tomohisa Hatta3 , Tohru Natsume3 , Noboru Mizushima1 (epartment of Biochemistry and Molecular Biology, Graduate School and Faculty of Medicine, The University of Tokyo1 , Department of Respiratory Medicine, The University of Tokyo2 , Molecular Profi ling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technol- ogy (AIST) 3 ) WS14-04 09:36-09:48 Elucidating the mechanism of selective mitochondrial (P2-077) fusion by OPA1 and cardiolipin ○ Tadato Ban, Naotada Ishihara (Dept. of Protein Biochem., Inst. of Life Science, Kurume Univ.) WS14-05 09:48-10:00 Degradation pathway mediated by the two AAA-ATPase (P2-085) Msp1 and Cdc48 for the mistargeted tail-anchored pro- teins on the mitochondrial outer membrane ○ Shunsuke Matsumoto1 , Kunio Nakatsukasa2 , Yasushi Tamura3 , Masatoshi Esaki4 , Toshiya Endo1 (Kyoto sangyo univ. 1, Nagoya city univ.2 , Yamagata univ.3 , Kumamoto univ.4 ) WS14-06 10:00-10:12 Physical modeling for mitochondrial shape and size reg- (P2-052) ulation ○ Masashi Tachikawa (Riken) WS14-07 10:12-10:24 Peroxisomes govern mitochondrial dynamics and the (P1-028) mitochondrial-dependent apoptotic pathway ○ Hideaki Tanaka, Yukiko Gotoh, Tomohiko Okazaki (University of Tokyo, Pharmaceutical Science, Molecular Biology) WS14-08 10:24-10:36 Visualization of GPI-anchored proteins sorting in the ER (P2-084) ○ Kazuo Kurokawa 1 , Atsuko Ikeda 2 , Koichi Funato 2 , Manuel Muñiz3 , Akihiko Nakano1 (Riken RAP 1 , Hiroshima Univ.2 , Univ. of Seville3 ) WS14-09 10:36-10:48 Lemur kinase 1 (LMTK1) regulates dendritic spine for- (P2-073) mation negatively through Rab11 GAP Hironori Nishino1 , Akiko Asada1 , Taro Saito1 , Kanae Ando1 , Mineko Tomomura2 , Mitsunori Fukuda3 , ○ Shin-ichi Hisanaga1 (Tokyo Metropolitan University1 , Meikai University2 , Tohoku University3 ) WS14-10 10:48-11:00 Development of scanning ion conductance microscopy

90 and confocal microscopy hybrid system for visualizing the distribution of dendritic mitochondria ○ Hiroki Higashi1 , Yuanshu Zhou1 , Takafumi Miyamoto1 , Yuka Takeda2 , Noritaka Nakamichi2 , Yuri E Korchev3 , Takeshi Fukuma 1 , Yasufumi Takahashi1 (Division of Electrical Engineer- ing and Computer Science, Kanazawa University, Japan1 , Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Science, Kanazawa University, Japan2 , Department of Medicine, Imperial College London, United Kingdom3 )

Workshop 15：Cell adhesion / ECM / Cell-cell interaction / Mechanobiology (2) & Diff erentiation / Regen- eration / Stem cells (4)

DATE: June 8 (Fri) 9:00-11:00 Room D Chairperson: Junichi Ikenouchi (Kyushu Univ.) Makoto Ikeya (Kyoto Univ.) WS15-01 09:00-09:12 Roles of membrane lipids in the formation of tight junc- (P1-101) tion ○ Kenta Shigetomi1 , Junichi Ikenouchi2,3 (Graduate school of Sys- tem Life Sciences, Kyushu University1 , Department of Biology, Faculty of Sciences, Kyushu University2 , AMED-PRIME 3 ) WS15-02 09:12-09:24 ZO family proteins regulate epithelial polarity indepen- (P3-013) dent of Tight Junction strand assembly ○Tetsuhisa Otani1,2 , Mikio Furuse 1,2 (National Institute for Physio- logical Sciences1 , Graduate University for Advanced Studies (SOKENDAI) 2 ) WS15-03 09:24-09:36 Regulation of intercellular junction growth by apical tri- (P3-008) cellular junctions ○ Hiroyuki Uechi, Daiki Umetsu, Erina Kuranaga (Laboratory for Histogenetic Dynamics, Graduate School of Life Sciences, Tohoku University) WS15-04 09:36-09:48 A Drosophila Toll-like receptor family protein prevents (P3-014) cell mixing through homophilic adhesion during epithe- lial morphogenesis ○Daiki Umetsu, Norihiro Iijima, Erina Kuranaga (Tohoku Uni- versity, Graduate School of Life Sciences)

91 WS15-05 09:48-10:00 Functional roles of Rho-GEF PLEKHG4B in the forma- (P1-088) tion of adherens junctions ○ Komaki Ninomiya, Kensaku Mizuno, Kazumasa Ohashi (Labo- ratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University) WS15-06 10:00-10:12 Functional analysis of alpha-catenin on coordinated epi- (P1-094) thelial morphogenesis ○ Ryosuke Nishimura1 , Masahiro Takeda2 , Hiromi Miyoshi2,3 , Yutaka Yamagata2 , Shigenobu Yonemura1,4 (Grad. Sch. of Med. Sci., Tokushima Univ.1 , RIKEN CAP 2, Grad. Sch. Sys. Desn., Tokyo Metropolitan Univ.3 , RIKEN CLST 4 ) WS15-07 10:12-10:24 Ribosomes convert human fibroblasts to multipotent cells ○ Kunimasa Ohta, Shah Adil Ishtiyaq Ahmad, Mohammad Badrul Anam, Naofumi Ito (Kumamoto University) WS15-08 10:24-10:36 T winning: Embryonic Regeneration by Relocalization of (P3-077) the Spemann Organizer in Xenopus ○ Yuki Moriyama1 , Edward M. De Robertis 2,3, Akimasa Fukui 1 (Chuo University 1, Howard Hughes Medical Institute2 , University of California, Los Angeles3 ) WS15-09 10:36-10:48 Developmental origin and induction processes of hair (P3-096) follicle stem cells ○ Ritsuko Morita1 , Noriko Sanzen1 , Tetsutaro Hayashi2 , Mana Umeda2 , Mika Yoshimura2 , Itoshi Nikaido2 , Takaya Abe3 , Hiroshi Kiyonari3,4 , Yasuhide Furuta3,4 , Hironobu Fujiwara1 (Laboratory for Tissue Microenvironment, RIKEN CDB1 , Bioinformatics Research Unit, RIKEN ACCC2 , Animal Resource Development Unit, Division of Bio-Function Dynamics Imaging, RIKEN CLST3 , Genetic Engineering Team, Division of Bio-Function Dynamics Imaging, RIKEN CLST4 ) WS15-10 10:48-11:00 T-SNARE Protein Syntaxin-4 as a Possible Regulator of (P1-142) Human Stem Cell Pluripotency ○ Thassya Obata, Yohei Hirai (Department of Biomedical Chem- istry, Graduate School of Science and Technology, Kwansei Gakuin University)

92 Workshop 16： Theoretical biology / Modeling & Evolution (EcoDevo / EvoDevo) DATE: June 8 (Fri) 9:00-11:00 Room E Chairperson: Naoki Irie (Univ. of Tokyo) Hiroshi Wada (Univ. of Tsukuba) WS16-01 09:00-09:12 Mathematical modeling of morphallactic regeneration in Enchytraeus japonensis: A new model for segment for- mation and its possible molecular mechanisms ○Chikako Yoshida-Noro1,2 , Yusuke Shibasaki3 , Minoru Saito4 (College of Industrial Technology, Nihon University1 , Nihon Uni- versity School of Medicine2 , Graduate School of Integrated Basic Sciences, Nihon University3 , College of Humanities and Sci- ences, Nihon University4 ) WS16-02 09:12-09:24 Origin of adaptation and modularity in chemical reaction networks Takashi Okada1 , Je-Chiang Tsai2 , ○Atsushi Mochizuki1,3 (Theor. Biol. Lab., RIKEN, Japan 1 , Dept. Math., Natl. Tsing Hua Univ., Taiwan2 , CREST, JST3 ) WS16-03 09:24-09:36 Mathematical analysis of orixate phyllotaxis (P1-158) ○ Takaaki Yonekura1 , Akitoshi Iwamoto2 , Hironori Fujita3 , Mune- taka Sugiyama1 (Univ. Tokyo1 , Tokyo Gakugei Univ.2 , Natl. Inst. Basic Biol.3 ) WS16-04 09:36-09:48 Information transmission of insulin signal transduction (P3-107) based on live-cell sensing and information theoretic approach ○Katsuyuki Kunida1,2 , Shinsuke Uda3 , Takumi Wada2 , Haruki Inoue4 , Shinya Kuroda2,4 (Laboratory of Computational Biology Graduate School of Biological Sciences, Nara Institute of Science and Technology1 , Department of Biological Sciences, Graduate School of Science, University of Tokyo2 , Division of Integrated Omics, Research Center for Transomics Medicine, Medical Insti- tute of Bioregulation, Kyushu University3 , Department of Com- putational Biology and Medical Sciences, Graduate school of Frontier Sciences, University of Tokyo4 ) WS16-05 09:48-10:00 Inhibitory signal on FGF-mediated Msx1 induction in (P3-127) the mandibular arch may contribute to the diversifi cation of heterodont dentition among mammals.

93 ○Yoshio Wakamatsu1 , Shiro Egawa2 , Yukari Terashita 3 , Noriko Osumi 1, Hiroshi Kawasaki 3, Koji Tamura2 , Kunihiro Suzuki 4 (Tohoku Univ., Grad. Sch. Med.1 , Tohoku Univ., Grad. Sch. Life Sci.2 , Kanazawa Univ., Grad. Sch. Med.3 , Nihon Univ. Sch. Dent. Ma tsudo4 ) WS16-06 10:00-10:12 Heterochrony in initiation of Gdf11 expression specifi es (P3-131) unique hindlimb positioning through coordination of Hox gene expression in tetrapods ○ Takayuki Suzuki1 , Yoshiyuki Matsubara1 , Hikaru Kasahara1 , Tatsuya Hirasawa2 , Shiro Egawa3 , Ayumi Hattori4 , Takaya Su ganuma1 , Yuhei Kohara1 , Tatsuya Nagai1 , Koji Tamura3 , Shigeru Kuratani2 , Atsushi Kuroiwa1 (Nagoya Univ.1 , RIKEN2 , Tohoku Univ.3 , IDAC 4 ) WS16-07 10:12-10:24 Hox genes of the last common ancestor of vertebrates were expressed following whole-cluster temporal collin- earity ○Juan Pascual-Anaya1 , Iori Sato1 , Fumiaki Sugahara1,2 , Shinno- suke Higuchi 1, Jordi Paps 3, Ren Yandong 4,5, Wataru Takagi1 , Adrián Ruiz-Villalba6 , Kinya G. Ota 7, Wen Wang4 , Shigeru Kuratani1 (Evolutionary Morphology Laboratory, RIKEN, Kobe 650-0047, Japan1 , Division of Biology, Hyogo College of Medi- cine, Nishinomiya 663-8501, Japan2 , School of Biological Sci- ences, University of Essex, Colchester CO4 3SQ, UK3 , State Key Laboratory of Genetic Resources and Evolution, Kunming Insti- tute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.4 , University of Chinese Academy of Sciences, , 100049, China5 , Cell Therapy Program, Foundation of Applied Medical Research (FIMA), University of Navarra, Pam- plona, Spain6 , Laboratory of Aquatic Zoology, Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, Yilan 26242, Taiwan7 ) WS16-08 10:24-10:36 Constrained variation of floral organ arrangement in (P3-129) basal eudicots: a correlation with species diversity of the organ number. ○ Koichi Fujimoto, Miho S. Kitazawa (Osaka University) WS16-09 10:36-10:48 Tissue-specific regulation of yellow gene expression in (P3-132) Bombyx mori ○ Takao K Suzuki1 , Shigeyuki Koshikawa2 , Isao Kobayashi 1 , Keiro Uchino1 , Hideki Sezutsu1 (National Agriculture and Food

94 Research Organization (NARO)1 , Hokkaido University2 ) WS16-10 10:48-11:00 Evolution of larval skeletogenic mechanism: develop- (P3-134) mental system drift in echinoderm ○ Atsuko Yamazaki, Yoshiaki Morino, Hiroshi Wada (University of Tsukuba)

Workshop 17：Nutrition / Metabolism & Disease / Pathology / Pathogenesis DATE: June 8 (Fri) 9:00-11:00 Room F Chairperson: Masamitsu Yamaguchi (KIT) Takashi Kojima (Sapporo Medical Univ.) WS17-01 09:00-09:12 W arburg-like metabolism coordinates FGF and Wnt sig- (P1-155) naling in the vertebrate embryo ○ Masayuki Oginuma, Yukiko Harima, Olivier Pourquie (Harvard Medical School, Brigham and Women’s Hospital, Gunma Uni- versity Institute for Molecular and Cellular Regulation) WS17-02 09:12-09:24 The polyol pathway is the principal sugar-sensing path- way for sugar-responsive gene expression mediated by Mondo/ChREBP ○ Hiroko Sano1 , Akira Nakamura2 , Mariko Yamane3 , Hitoshi Niwa 3, Masayasu Kojima 1 (Department of Molecular Genetics, Institute of Life Science, Kurume University, Japan1 , Department of Germline Development, Division of Organogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Japan2 , Department of Pluripotent Stem Cell Biology, Division of Stem Cell Research, Institute of Molecular Embryology and Genetics, Kumamoto University, Japan3 ) WS17-03 09:24-09:36 A Novel Function of Docosahexaenoic Acid (DHA) for Neuronal Primary Cilia Formation Kento Karita, Shinichiro Suzuki, Naoyuki Inagaki, ○ Michinori Toriyama (Nara Institute of Science and Technology) WS17-04 09:36-09:48 Fluorescence temperature imaging reveals a potential (P3-103) role of mitochondrial pH changes in initiating brown adipocytes activation ○ Madoka Suzuki1,2 , Yoshie Harada1 (Inst. for Protein Res., Osaka Univ.1 , PRESTO, JST 2 )

95 WS17-05 09:48-10:00 Early-life exposure to low-dose oxidants canincrease (P3-111) longevity via microbiome remodelling in Drosophila ○ Fumiaki Obata1,2 , Clara O. Fons 2 , Alex P. Gould 2 (The Univer- sity of Tokyo1 , The Francis Crick Institute2 ) WS17-06 10:00-10:12 Subcellular localization and functional analyses of Dro- (P1-164) sophila SLC25A46, mitochondrial diseases causing gene. ○Kojiro Suda, Hideki Yoshida, Masamitsu Yamaguchi (Kyoto Institute of Technology) WS17-07 10:12-10:24 Molecular commonalities between auditory hair cells (P3-117) and neurons in the study of age-related neuronal disorder ○ Leo Tsuda, Ryunosuke Minami, Young-Mi Lim (National Cen- ter for Gariatrics and Gerontology) WS17-08 10:24-10:36 HNRNPLL is a novel metastasis suppressor of colorectal (P3-121) cancer, and modulates alternative splicing of CD44 dur- ing epithelial-mesenchymal transition ○Masahiro Aoki, Keiichiro Sakuma (Aichi Cancer Center Research Institute) WS17-09 10:36-10:48 Dynamin 2 mutation in Charcot-Marie-Tooth disease (P3-122) disturbs reorganization of actin cytoskeleton in glomeru- lar podocyte ○ Kohji Takei1 , Natsuki Wakita1 , The Mon La 1 , Kento Sumida 1 , Moin Saleem 2 , Tetsuya Takeda1 , Hiroshi Yamada1 (Okayama Uni- versity1 , Bristol University2 ) WS17-10 10:48-11:00 Drosophila Ubiquilin depletion reveals the impact of proteostasis impairment on locomotive and learning abilities ○ Salinee Jantrapirom1 , Luca Lo Piccolo2 , Hideki Yoshida1 , Masamitsu Yamaguchi1 (Kyoto Institute of Technology1 , Osaka University Graduate School of Medicine2 )

96