RASA4 Antibody Cat. No.: 23-946

RASA4 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 IMMUNOGEN: of human RASA4 (NP_008920.5).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:500 - 1:2000

POSITIVE CONTROL: 1) SH-SY5Y

2) 293T

3) Mouse thymus

4) Mouse spleen

PREDICTED MOLECULAR Observed: 100kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

September 24, 2021 1 https://www.prosci-inc.com/rasa4-antibody-23-946.html ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: RASA4

CAPRI, GAPL, ras GTPase-activating protein 4, Ca2+-promoted Ras inactivator, calcium- ALTERNATE NAMES: promoted Ras inactivator, rasGAP-activating-like protein 2

GENE ID: 10156

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is BACKGROUND: converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 24, 2021 2 https://www.prosci-inc.com/rasa4-antibody-23-946.html