RASA4 Antibody Cat. No.: 23-946 RASA4 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human, Mouse, Rat Recombinant fusion protein containing a sequence corresponding to amino acids 60-290 IMMUNOGEN: of human RASA4 (NP_008920.5). TESTED APPLICATIONS: WB APPLICATIONS: WB: ,1:500 - 1:2000 POSITIVE CONTROL: 1) SH-SY5Y 2) 293T 3) Mouse thymus 4) Mouse spleen PREDICTED MOLECULAR Observed: 100kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal September 24, 2021 1 https://www.prosci-inc.com/rasa4-antibody-23-946.html ISOTYPE: IgG CONJUGATE: Unconjugated PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: RASA4 CAPRI, GAPL, ras GTPase-activating protein 4, Ca2+-promoted Ras inactivator, calcium- ALTERNATE NAMES: promoted Ras inactivator, rasGAP-activating-like protein 2 GENE ID: 10156 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is BACKGROUND: converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 24, 2021 2 https://www.prosci-inc.com/rasa4-antibody-23-946.html.