Appendix: List of codes used to create the study cohort and characterize surgery
ICD-9 codes used to identify infectious endocarditis
4210 Acute/subacute bacterial endocarditis
4211 Acute endocarditis
4219 Acute/subacute endocarditis not otherwise specified
4249 Endocarditis not otherwise specified
ICD-10 codes used to identify infectious endocarditis
I330 Acute and subacute infective endocarditis
I339 Acute endocarditis, unspecified
I38 Endocarditis, valve unspecified
ICD-9 codes used to identify substance use disorder
2920 Drug withdrawal syndrome
2921 Drug paranoid state
2922 Pathologic drug intoxication
2928 Drug-induced delirium
2929 Drug mental disorder not otherwise specified
3040 Opioid dependence unspecified
3041 Barbiturate dependence unspecified
3042 Cocaine dependence unspecified
3045 Hallucinogen dependence unspecified
3049 Drug dependence not otherwise specified unspecified
3053 Hallucinogen abuse
3054 Barbiturate abuse unspecified
3055 Opioid abuse unspecified
3056 Cocaine abuse unspecified 3059 Drug abuse NEC unspecified
3044 Amphetamine dependence unspecified
3046 Drug dependence NEC unspecified
3047 Opioid/other dependence unspecified
3048 Combined drug dependence NEC unspecified
3057 Amphetamine abuse unspecified
3058 Antidepressant abuse unspecified
ICD-10 codes used to identify substance use disorder
F110 Mental and behavioural disorders due to use of opioids, acute intoxication
F111 Mental and behavioural disorders due to use of opioids, harmful use
F112 Mental and behavioural disorders due to use of opioids, dependence syndrome
F113 Mental and behavioural disorders due to use of opioids, withdrawal state
F114 Mental and behavioural disorders due to use of opioids, withdrawal state with delirium
F115 Mental and behavioural disorders due to use of opioids, psychotic disorder
F116 Mental and behavioural disorders due to use of opioids, amnesic syndrome
F117 Mental and behavioural disorders due to use of opioids, residual and late-onset psychotic disorder
F118 Mental and behavioural disorders due to use of opioids, other mental and behavioural disorders
F119 Mental and behavioural disorders due to use of opioids, unspecified mental and behavioural disorder
F130 Mental and behavioural disorders due to use of sedatives or hypnotics, acute intoxication
F131 Mental and behavioural disorders due to use of sedatives or hypnotics, harmful use
F132 Mental and behavioural disorders due to use of sedatives or hypnotics, dependence syndrome
F133 Mental and behavioural disorders due to use of sedatives or hypnotics, withdrawal state
F134 Mental and behavioural disorders due to use of sedatives or hypnotics, withdrawal state with
delirium
F135 Mental and behavioural disorders due to use of sedatives or hypnotics, psychotic disorder
F136 Mental and behavioural disorders due to use of sedatives or hypnotics, amnesic syndrome F137 Mental and behavioural disorders due to use of sedatives or hypnotics, residual and late-onset
psychotic disorder
F138 Mental and behavioural disorders due to use of sedatives or hypnotics, other mental and
behavioural disorders
F139 Mental and behavioural disorders due to use of sedatives or hypnotics, unspecified mental and
behavioural disorder
F140 Mental and behavioural disorders due to use of cocaine, acute intoxication
F141 Mental and behavioural disorders due to use of cocaine, harmful use
F142 Mental and behavioural disorders due to use of cocaine, dependence syndrome
F143 Mental and behavioural disorders due to use of cocaine, withdrawal state
F144 Mental and behavioural disorders due to use of cocaine, withdrawal state with delirium
F145 Mental and behavioural disorders due to use of cocaine, psychotic disorder
F146 Mental and behavioural disorders due to use of cocaine, amnesic syndrome
F147 Mental and behavioural disorders due to use of cocaine, residual and late-onset psychotic disorder
F148 Mental and behavioural disorders due to use of cocaine, other mental and behavioural disorders
F149 Mental and behavioural disorders due to use of cocaine, unspecified mental and behavioural
disorder
F160 Mental and behavioural disorders due to use of hallucinogens, acute intoxication
F161 Mental and behavioural disorders due to use of hallucinogens, harmful use
F162 Mental and behavioural disorders due to use of hallucinogens, dependence syndrome
F163 Mental and behavioural disorders due to use of hallucinogens, withdrawal state
F164 Mental and behavioural disorders due to use of hallucinogens, withdrawal state with delirium
F165 Mental and behavioural disorders due to use of hallucinogens, psychotic disorder
F166 Mental and behavioural disorders due to use of hallucinogens, amnesic syndrome
F167 Mental and behavioural disorders due to use of hallucinogens, residual and late-onset psychotic
disorder
F168 Mental and behavioural disorders due to use of hallucinogens, other mental and behavioural
disorders F169 Mental and behavioural disorders due to use of hallucinogens, unspecified mental and behavioural
disorder
F190 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
acute intoxication
F191 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
harmful use
F192 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
dependence syndrome
F193 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
withdrawal state
F194 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
withdrawal state with delirium
F195 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
psychotic disorder
F196 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
amnesic syndrome
F197 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
residual and late-onset psychotic disorder
F198 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
other mental and behavioural disorders
F199 Mental and behavioural disorders due to multiple drug use and use of psychoactive substances,
unspecified mental and behavioural disorder
OHIP codes used to identify substance use disorder
304 Drug dependence, drug addiction
CCI codes used to determine if surgery was performed
1.HS.80.^^ Repair, triscuspid valve 1.HS.90.^^ Excision total with reconstruction, tricuspid valve
1.HT.89.^^ Excision total, pulmonary valve
1.HT.90.^^ Excision total with reconstruction, pulmonary valve
1.HU.80.GP-FF Repair, mitral valve, percutaneous transluminal approach using edge to edge leaflet
closure device
1.HU.80.LA Repair, mitral valve, open approach using suture [e.g. annular plication, semicircular
annuloplasty]
1.HU.80.LA-FE Repair, mitral valve, open approach using prosthetic device [e.g. ring, Future band
annuloplasty]
1.HU.80.LA-XX- Repair, mitral valve, open approach using autograft [e.g. patching leaflet with
A pericardial tissue]
1.HU.80.PN Repair, mitral valve, robotic assisted (minimally invasive) approach with
telemanipulation of tools using suture [e.g. annular plication, semicircular
annuloplasty]
1.HU.80.PN-BD Repair, mitral valve, robotic assisted (minimally invasive) approach with
telemanipulation of tools using balloon [e.g. balloon valvuloplasty]
1.HU.80.PN-BP Repair, mitral valve, robotic assisted (minimally invasive) approach with
telemanipulation of tools using dilation device [e.g. expanding dilator]
1.HU.80.PN-FE Repair, mitral valve, robotic assisted (minimally invasive) approach with
telemanipulation of tools using prosthetic device [e.g. ring, Future band
annuloplasty]
1.HU.80.PN-XX- Repair, mitral valve, robotic assisted (minimally invasive) approach with
A telemanipulation of tools using autograft [e.g. patching leaflet with pericardial tissue]
1.HU.90.^^ Excision total with reconsutrction, mitral valve
1.HV.80.LA Repair, aortic valve open approach using suture (e.g. annular plication, semicircular
annuloplasty)
1.HV.80.LA-FE Repair, aortic valve open approach using prosthetic device (e.g. ring annuloplasty) 1.HV.80.LA-XX- Repair, aortic valve open approach using autograft (e.g. patching of leaflet with
A pericardial tissue)
1.HV.90.^^ Excision total with reconstruction, aortic valve
CCP codes used to determine if surgery was performed
47.97 Percutaneous valvuloplasty
47.14 Open heart valvuloplasty of tricuspid valve without replacement
47.04 Closed heart valvotomy, tricuspid valve
47.27 Other replacement of tricuspid valve
47.26 Replacement of tricuspid valve with tissue graft
47.05 Closed heart valvotomy, pulmonary valve
47.29 Other replacement of pulmonary valve
47.28 Replacement of pulmonary valve with tissue graft
47.12 Open heart valvuloplasty of mitral valve without replacement
47.02 Closed heart valvotomy, mitral valve
47.23 Other replacement of mitral valve
47.22 Replacement of mitral valve with tissue graft
47.13 Open heart valvuloplasty of aortic valve without replacement
47.03 Closed heart valvotomy, aortic valve
47.25 Other replacement of aortic valve
47.24 Replacement of aortic valve with tissue graft