PDF Output of CLIC (clustering by inferred co-expression)

Dataset: Num of in input set: 38 Total number of genes: 16493

CLIC PDF output has three sections:

1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set.

Red lines shows the partition of input genes into CEMs, ordered by CEM strength.

Each row shows one gene, and the brightness of squares indicates its correlations with other genes.

Gene symbols are shown at left side and on the top of the heatmap.

2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets.

Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows).

Each column is one GEO series dataset, sorted by their posterior probability of being selected.

The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset.

CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score.

3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset.

Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Fam109b Fam109a Dennd1b Dennd1c Dennd1a Pik3c2a Sh3bp4 Vamp3 Vamp2 Slc2a4 Num ofGenesinQueryGeneset:38.CEMs:0. Overview ofCo-ExpressionModules(CEMs)withDatasetWeighting Ap1g1 Rgs19 Snx18 Fcho2 Fcho1 Clint1 Sgip1 Clvs2 Clvs1 Wipi1 Scyl2 Hip1r Sort1 Gga2 Aqp2 Epn3 Snx9 Aak1 Tnk2 Mlc1 Lrp1 Hip1 Dvl2 Dvl1 Stx6 Ocrl Mall Cltc

Slc2a4 Sh3bp4 Snx18 Dvl2 Rgs19 Aqp2 Aak1 Vamp2 Pik3c2a Stx6 Snx9 Sort1 Ap1g1 Dennd1a Hip1 Epn3 Sgip1 Mall Hip1r Gga2 Fcho1 Dennd1b Clvs1 Dennd1c Vamp3 Scyl2 Fcho2 Clvs2 Fam109b Ocrl Wipi1 Cltc Lrp1 Mlc1 Tnk2 Dvl1 Clint1 Fam109a 0.0 Singletons Scale ofaveragePearsoncorrelations 0.2 0.4 0.6 0.8 1.0