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Physiologynews PHYSIOLOGYNEWS summer 2006 | number 63 Meetings UCL Brazil Manchester Munich Also featuring: Trials and tribulations of self-experimentation Alison Brading’s 10 key papers A century of physiology online Working out aerobic fitness Bursting with currents Granny’s going global A publication of The Physiological Society 1 MANCHESTER FOCUSED MEETING Frontiers in epithelial transport 6–7 April 2006 12 2 11 13 3 10 14 9 4 1 Welcome reception, Whitworth Art Gallery 2 David Sheppard (Bristol), left, defends his poster to Seth Alper (Harvard) and Barry Argent (Newcastle) 3 Poster session 4 Welcome reception 5 Lowry Centre 8 entrance 6 Conference dinner at the Lowry Centre 7 The speakers 8 Poster Prize winner Jennifer Evans (Glasgow) 9 Martin Steward (Manchester), 2nd right, 5 shares a joke with Masataka Murakami (Okazaki), 2nd left, and Hiroshi Ishiguro (Nagoya) 10 Jim Melvin (Rochester), left, and Shmuel Muallen (Dallas) 11 Speakers (from left) David Cook (Sydney), Mike Gray (Newcastle) and Karl Kunzelmann (Regensburg) 12 Craig Smith (Manchester), left, and Jeppe Praetorius (Aarhus) at the Lowry Centre gallery 13 Boarding deluxe transport to the conference dinner 14 Conference chair Maynard Case passes round the begging bowl. 7 6 (photos by Austin Elliott, Simon Kellas and Donald Ward) PHYSIOLOGYNEWS Editorial 3 Meetings Physiology at UCL in 2006 John Carroll 4, 15 The Society’s dog. ‘Rudolf Magnus gave Joint International Meeting with the Brazilian Physiological me to Charles Sherrington, who gave me Society José Antunes-Rodrigues 6 to Henry Dale, who gave me to the Images of Manchester inside front cover Physiological Society in October 1942’ Images of Munich 25 IUPS David Eisner, Akimichi Kaneko, Ole Petersen 7 My 10 key papers Alison Brading 9 Published quarterly by the Physiological Society Living history Contributions and Queries My own subject Hugh de Wardener 13 Executive Editor Linda Rimmer Features The Physiological Society Publications Office Targeted cell based delivery of siRNA PR Brink, V Valiunas, S Doronin, P.O. Box 502 Cambridge CB1 0AL I Potapova, RB Robinson, MR Rosen, T Mathias, IS Cohen 16 UK Working out aerobic fitness Ole Kemi, Per Haram, Ulrik Wisløff, Øyvind Ellingsen 18 Tel: +44 (0)1223 400180 Erythropoietin controls ventilation in hypoxia Jorge Soliz, Joseph Fax: +44 (0)1223 246858 Email: [email protected] Vincent, Omolara Ogunshola, Max Gassmann 20 The Society web server: http://www.physoc.org Bursting with currents Wenbo Zhang, Thomas Fisher 22 Developing insights into Purkinje cell maturation Bruce McKay, Magazine Editorial Board Ray Turner 24 Editor Austin Elliott (University of Manchester) Muscle mass at the top: a likely role for fibre hyperplasia in Members humans Giuseppe D’Antona 26 Lesley Anson (Nature) Cardiac channelopathies studied with the dynamic action Patricia de Winter (King’s College London) potential clamp technique Géza Berecki, Antoni van Ginneken 28 Sarah Hall (University of Cardiff) Munir Hussain (University of Liverpool) Reduced mitochondrial efficiency: dysfunction or defence in ageing John Lee (Rotherham General Hospital) muscle? David Marcinek 30 Thelma Lovick (University of Birmingham) Bill Winlow (Prime Medica, Knutsford) Granny’s going global Alister Nicol, Hanno Fischer, Andrew Tate, Keith Kendrick 32 © 2006 The Physiological Society ISSN 1476-7996 Letters to the Editor 34 The Society permits the single copying of Reports individual articles for private study or research. For Goal-directed limb movements Tom Matheson copying or reproduction for any other purpose, written permission must be sought from The ‘Northern’ Cardiovascular Research Group Matthew Physiological Society ([email protected]). Lancaster, Sarah Calaghan 35 Opinions expressed in articles and letters submitted NC3Rs Stakeholder Meeting Tim Watson 36 by, or commissioned from, Members, Affiliates or Moving forward with neuromuscular transmission Colin Ingram, outside bodies are not necessarily those of The Richard Ribchester 37 Physiological Society. The Society’s journals The Physiological Society is registered in England Experimental Physiology Emma Ward 38 as a company limited by guarantee: No 323575. Registered office: PO Box 11319, London WC1X A century (and more) of physiology now online Carol Huxley 40 8WQ Registered Charity: No 211585. Affiliate News Babies and the bench Dola Akanmu 41 Printed by The Lavenham Press Ltd Memorable Members Henry Barcroft Ian Roddie 42 Cover photos Front. The auto-icon of Jeremy Bentham (JB) will be Society News welcoming you to The Physiological Society meeting at UCL in July. In the formation of UCL, JB provided financial Parliamentary and Scientific Committee Ian McGrath 43 support and much of the spirit behind the ethos of what UCL New Chief Executive and President Giovanni Mann 44 would stand for as an institution. Established in 1828 using money raised through selling shares, UCL was originally Biosciences Federation Richard Dyer 45 known as the University of London before being rebranded Unbelievable! 46 as University College London in 1836. The first University established in England after Oxford and Cambridge. It was formed by, what JB described Obituaries as an 'association of liberals' and as such UCL was the first university not to discriminate on the basis of sex or faith (Source: Harte N & North J. The David Greenfield Robert Graham, David Banks, Peter Fentem, world of UCL 1828-2004). Ian Roddie 47 Autar Paintal Tim Biscoe 49 Back. The quad, University College London Book Reviews 51 Noticeboard 52 PHYSIOLOGYNEWS Action points Guidelines for contributors In this issue Grants These guidelines are intended to assist Welcome to the Summer 2006 edition of For full information on Members’ authors in writing their contributions and to Physiology News, with our usual mix of and Affiliates’ Travel Grants, reduce the subsequent editing process. The features. The scientific articles range Network Interaction Grants, Non- Editorial Board of Physiology News tries to from molecules to man (to borrow a ensure that all articles are written in a Society Symposia Grants, Vacation phrase), including Alison Brading’s 10 key Studentship Scheme, Departmental journalistic style so that they will have an immediate interest value for a wide papers (p. 9) , and a jaw-dropping Seminar Scheme, Centres of readership and will be readable and account from Hugh de Wardener of the Excellence and Junior Fellowships comprehensible to non-experts. In kind of experiments a physiologist could visit: http://www.physoc.org/grants particular, scientific articles should give a carry out on himself back in the days good overview of a field rather than focus before ethics committees (p 13). Membership applications entirely on the authors’ own research. Applications for Full and Affiliate We also report on a couple of notable Membership are received throughout Format of articles announcements. Firstly, The The main message or question posed should be the year and have no deadlines. A introduced in the first paragraph. The background Physiological Society has a new Chief decision is normally made within 7 for the topic should then be established, leading Executive and a new President-Elect days of the Administration Office up to the final conclusion. (p. 44), and secondly the full back­ receiving the application. For full catalogue of The Society’s journals (right Length of articles back to 1878) is now live online (p. 40). details please visit: This will be determined by the subject matter and http://www.physoc.org/join agreed with the Executive Editor. Eagle-eyed readers may spot that this Submission of articles Change of address issue is missing our regular diary feature Authors should submit articles as a Word A Week in the Life. I am sad about this, Members should inform the document attached to an email. Illustrations Administration Office of any changes should be sent as separate attachments (see below) as a diary has appeared in every issue of address, telephone, fax or email and not embedded in the text. since Alan North kicked off the feature in address. PN 55 (Summer 2004). But we had no Illustrations and authors’ photographs volunteers this time, and we finally seem Changes can be emailed to: Authors are encouraged to submit diagrams, to have run out of people that the editorial [email protected] or updated drawings, photographs or other artwork with their articles or to suggest appropriate illustrations. A team have enough incriminating material online at http://www.physoc.org photograph of the author(s) should also on to ‘persuade’ them to become diarists. accompany submissions, if possible. Illustrations However, every threat is another and photographs may be colour or black and white, prints, transparencies or tif/jpeg files with a opportunity (©your head of department), minimum resolution of 300 dpi. Electronic so any would-be diarists out there, get Physiology News colour figures should be saved in CMYK mode. writing. Why not keep a diary of your next conference trip? Or a week of exam Deadlines References Authors are requested to keep the number of season hell? Otherwise I might have to Letters and articles and all other references to a minimum – preferably no more write the next one myself. contributions for inclusion in the than two or three. Please cite all references in the Autumn 2006 issue, No. 64, should style of The Journal of Physiology (see reach the Publications Office Instructions to Authors 2005 at Austin Elliott ([email protected]) by 30 June http://www.physoc.org) 2006. Short news items are encouraged and can usually be included as late copy if space permits. Suggestions for articles Suggestions for future articles are welcome. Please contact either the Executive Editor or a member of the Editorial Board of Physiology News (see contents page for details). Physiology News Online Physiology News is now available on The Society’s web site: Oi, ref! http://www.physoc.org. Unbelievable! (p. 46) EDITORIAL PN 3 repeatedly recognise the need for science teaching this process, along with the current and ex­ Scientists needed to be grounded in experimental work.
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