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The first International Congress of Neuroimmunology was held in Stresa, Italy, in 1982 and wasThe organized first International by Drs. Peter Congress O. Behan of Neuroimmunology and Federico Spreafico. was held The in secondStresa, Italy,International in Congress1982 and of wasNeuroimmunology organized by Drs. was Peter held O.in Philadelphia,Behan and Federico PA, and Spreafico. was organised The second by C.S. Raine andInternational Dale E. McFarlin. Congress It was of atNeuroimmunology this meeting in Philadelphiawas held in inPhiladelphia, 1987 that itPA, was and decided was to startorganised an international by C.S. Raine society, and the Dale International E. McFarlin. Society It was ofat Neuroimmunology,this meeting in Philadelphia and an election wasin 1987held forthat a it panel was decided of officers. to start C.S. anRaine international was elected society, President, the International John Newson-Davis Society Vice President,of Neuroimmunology, Robert Lisak andTreasurer an election and Kenethwas held Johnson for a panel Secretary, of officers. together Cedric with S. an InternationalRaine was Advisoryelected President,Board. The John Society Newson-Davis was incorporated Vice President,in 1988. Subsequent Robert Lisak meetings wereTreasurer in Jerusalem and Kenneth 1991 (Oder Johnson Abramsky Secretary, and togetherHaim Ovadia), with Amsterdaman International 1994 (KeeAdvisory Lucas), Board. Montreal 1998 (Jack Antel and Trevor Owens), Edinburgh 2001 (John Greenwood,The Society Sandra was Amor,incorporated David Baker, in 1988.John FazakerleySubsequent and meetingsAngela Vincent), were in and Jerusalem Venice 2004(Isralel) (Francesca 1991 Aloisi(Oder and Abramsky Gianvito and Martino). Haim DaleOvadia), McFarlin Amsterdam died unexpectedly (The Netherlands) in 1992 and the1994 Dale (Kee McFarlin Lucas), Lecture Montreal has (Canada) been a special1998 focus(Jack ofAntel the andISNI Trevormeetings Owens), since then.Edinburgh Henry McFarland(United Kingdom) gave the 2001 first (John Dale lectureGreenwood, in 1994 Sandra (Amsterdam), Amor, David Martin Baker, Raff theJohn second Fazakerley in Montreal and (1998), Angela the Vincent), third by JohnVenice Newsom-Davis (Italy) 2004 (Francescain Edinburgh Aloisi (2001) and andGianvito the fourth Martino), by Peter Nagoya Doherty (Japan) in Venice 2006 (2004).(Takeshi The firstTabira), ISNI LectureFort Worth was given (United by C. S. States)Raine in 2008 Edinburgh (Caroline (2001) C. atWhitacre the 6th ISNIand Congress,Michael theK. Racke) second and by SitgesAngelo (Spain) Vescovi 2010 in Venice(Pablo at theVilloslada, 7th ISNI Congress Bernardo and theCastellano, last one in FrancescFort Worth Graus, by Larry Isabel Steinman. Illa, Xavier Montalban). The by-laws were first drafted in 1988 and were then updatedDale McFarlin and ratified died by unexpectedly the General Meetingin 1992 andin Edinburgh the Dale in McFarlin2001. The Lecture by-laws has will been be a sent special to focusall new of membersthe ISNI meetings of the Society.since then. Henry McFarland gave the first Dale lecture in 1994 (Amsterdam). The Thefirst principal ISNI Lecture office wasof the given Society by Cedric is in S.Rome, Raine Italy, in Edinburgh and the executive(2001) at theoffice 6th is ISNI currently supervisedCongress. byThe Tomasby-laws Olsson were first (President) drafted inin 1988 coordination and were thenwith updatedGianvito and Martino ratified (Vice President)by the General and Roberto Meeting Furlan in Edinburgh(Treasurer in and 2001. Secretary). SinceThe 2010, principal the European office of Schoolthe Society of Neuroimmunology is in Rome, Italy, (ESNI) and is the the executiveofficial school office of the is ISNI andcurrently the first supervisedcongress day by is Tomas dedicated Olsson to the (President) ESNI. in coordination with Gianvito Martino (Vice President) and Roberto Furlan (Treasurer and Secretary). Since 2010, the European School of Neuroimmunology (ESNI) is the official school of the ISNI and the first congress day is dedicated to the ESNI. ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 1 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM Table of contents pag. 3 . .Welcome pag. 4 . .Committees pag. 5 . .Acknowledgements pag. 6 . .Grants pag. 7 . .General Information pag. 11 . .Invited Speakers pag. 13 . .12th ESNI Pre-Congress Teaching Course – Sunday November 4th pag. 14 . .11th ISNI Congress – Monday November 5th pag. 34 . .Tuesday November 6th pag. 56 . .Wednesday November 7th pag. 75 . .Thursday November 8th pag. 77 . .Index of Abstracts’ Authors 1 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 2 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 3 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM Welcome letter Local Organizing Committee on behalf of the International Society of Neuroimmunology (ISNI), we are pleased to invite you to participate in the Eleventh ISNI Congress, which will be held in Boston, USA, from November 4th- 8th, 2012. There are exciting developments in the field of Neuroimmunology affecting our understanding of neuroimmune diseases, the development of new immunotherapies, and new technology for research. Conference Chair The organizing Committee, on behalf of ISNI, is preparing an exciting program that will Samia Khoury inform participants on the latest developments in the field. The program will include Jack, Sadie and David Breakstone Professor of Neurology plenary sessions, focused symposia, and workshops. Plenty of time is devoted to poster Harvard Medical School, presentations. We want to see you there! Boston, MA, USA Co-Director Partners MS Center Boston, one of America’s oldest cities, has a rich economic and social history, and is home to many institutions of higher education, some of the world’s finest hospitals, and numerous cultural and professional sports organizations. Museums, places to visit and restaurants in the city will make this event a wonderful experience. We look forward to seeing you in Boston! Samia Khoury 3 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 4 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM Committees INTERNATIONAL SOCIETY OF NEUROIMMUNOLOGY INTERNATIONAL AdvISORY BOARd CONGRESS ORGANIzERS ISNI OFFICERS Congress Chair: Samia J. Khoury President - Tomas olsson, Sweden Jack, Sadie and David Breakstone Professor of Neurology, Vice President - Gianvito Martino, Italy Harvard Medical School, Boston, MA, USA Secretary/Treasurer - roberto furlan, Italy Co-Director Partners MS Center david A. Hafler HONORARY OFFICERS Gilbert H. Glaser Professor of Neurology, Jack Antel Montreal, Canada Yale School of Medicine, New Haven, CT, USA Trevor owens, odense, Denmark Cedric S. raine, New York, NY, USA vijay Kuchroo Angela Vincent, oxford, UK Samuel L. Wasserstrom Professor of Neurology, Harvard Hartmut Wekerle, Martinsried, Germany Medical School, Boston, MA, USA Caroline Whitacre, Columbus, oH, USA Steven Jacobson Senior Investigator, Viral Immunology Section at NIH, INTERNATIONAL AdvISORY BOARd Bethesda, MD, USA f. Aloisi, rome, Italy B. Becher, Zürich, Switzerland A. Coles, Cambridge, UK ORGANIzING SECRETARIAT r. Gold, Bochum, Germany EEM International Congress Services D. Hafler, Boston, MA, USA MICE & PCo W. Hickey, Dartmouth, MA, USA Professional Congress organizer & r. Hintzen, rotterdam, The Netherlands Associations Management Services V. Kuchroo, Boston, MA, USA www.eemservices.com r. Martin, Zürich, Switzerland Y. Matsumoto, Tokyo, Japan S. Miller, Chicago, IL, USA H. Perry, Southampton, UK L. Probert, Athens, Greece M. Schwartz, rehovot, Israel L. Steinman, Stanford, CA, USA P. Villoslada, Barcelona, Spain T. Yamamura, Tokyo, Japan W. Yong, Calgary, Canada 4 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 5 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM Acknowledgements In cooperation with: Supported by: Gold Sponsor: Silver Sponsors: Other Sponsors: Grants: Also thanks to: EMd Serono Inc. (Canada) Teva Canada Limited 5 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 6 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM CME Accreditation This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of CME outfitters, LLC and International Society of Neuroimmunology. CME outfitters, LLC is accredited by the ACCME to provide continuing medical education for physicians. CME outfitters designates this live activity for a maximum of 24 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. The The European Accreditation Council for CME (EACCME) and the American Medical Association (AMA) In 2000 the EACCME and the AMA signed an agreement of mutual recognition of CME credits between Europe and the USA whereby European physicians attending an event in the USA had their credits Category 1 recognised in Europe. other bilateral agreements may exhist between AMA ACCME and your local CME authority. 24 AMA PRA Category 1 CreditsTM Physicians should claim only the credit commensurate with the extent of their participation in the activity 6 ISNI_PROGRAMMA_SCIENTIFICO_2012 14OCT2012_Layout 1 15/10/12 17:56 Pagina 7 11th International Congress of Neuroimmunology SCIENTIfIC ProGrAM The first
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