Georgia CTSA Georgia Clinical & Translational Science Alliance

Certificate Program in Translational Research This innovative and rigorous program gives PhD students, postdocs, and junior faculty members at the Georgia Clinical & Translational Science Alliance (Georgia CTSA)- partner institutions the expertise and experience to translate fundamental biomedical scientific discoveries into treatments that will benefit human health.

NIH-FUNDED CLINICAL AND TRANSLATIONAL SCIENCE AWARD GEORGIA CLINICAL & TRANSLATIONAL SCIENCE ALLIANCE (GEORGIA CTSA) Georgia CTSA Georgia Clinical & Translational Science Alliance

Certificate Program in Physician postdoctoral fellows: Postdoctoral physicians, including senior residents and those in clinical/research specialty fellowship programs, who will have protected Translational Research time for CPTR may apply at any point in their postdoctoral training at Emory University School of Medicine and MSM. The Certificate Program in Translational Research (CPTR) is a multidisciplinary, Faculty: Physician and non-physician faculty members of all academic levels from innovative program that provides all four Georgia CTSA partner institutions, who will have protected time and tuition predoctoral or postdoctoral trainees and support for CPTR training may apply. junior faculty members with the expertise and experience to translate fundamental How to Apply • Original transcripts (if your biomedical scientific discoveries into application is successful) in sealed treatments that will benefit human health. Applicants should apply via the web- envelopes or directly emailed The certificate program requires 16 based CPTR application system from the issuing institution to the credits of didactic training in the Laney GeorgiaCTSA.org/CPTR/Apply.html Laney Graduate School from each Graduate School of Emory University. The Application deadline: There is a post-secondary institution you have courses are taught by faculty at Emory “rolling” deadline for predoctoral and attended. Transcripts are for the University, Morehouse School of Medicine postdoctoral CPTR applicants not Laney Graduate School per SACS (MSM), Georgia Institute of Technology applying through the TL1 mechanism requirements. They must be in (Georgia Tech), and University of Georgia English or accompanied by notarized Moriah Bellissimo, CPTR student and PhD or the junior faculty KL2 program. (UGA). candidate, applies the clinical assessment Applicants should apply by April 30. translations. Please hand-deliver Trainees may take the coursework method of testing hand grip strength to the Georgia CTSA Research over a single year or spread the work over of a patient in the Georgia CTSA Clinical The following items are required: Research Center at Emory University Education Programs office (see back two years for limited impact on the time Hospital. This test can be used as a • Cover sheet cover). required from their laboratory or clinical surrogate marker of nutritional status. • NIH-style Biosketch from applicant duties. There are no citizenship requirements. and lead mentor/advisor/supervisor • Personal statement (1-2 pages, single-spaced, 11 point font, 1 inch Eligibility margins) Predoctoral CPTR eligibility • Transcript from current program (required of PhD students) Graduate students: PhD-level graduate students from all four Georgia CTSA • Letter of recommendation from PhD partner institutions may apply in the subsequent year after passing comprehensive program director (not required of examinations at their institutions. postdocs or faculty members) PharmD students: Predoctoral trainees enrolled in the UGA College of Pharmacy • Letter of support from lead mentor may apply to the CPTR program after their second year of training. (not required of faculty members at associate or full professor level) Postdoctoral CPTR eligibility • Application fee (if your application Postdoctoral fellows with PhD, PharmD, or equivalent degrees: Postdoctoral is successful) of $75.00 payable to Translation to Clinical Medicine course director fellows from Emory, MSM, Georgia Tech, and UGA may apply at any point in their Vin Tangpricha, MD, PhD, and former CPTR student Emory University (unless currently Ellen Smith, PhD, providing informed consent to a postdoctoral training. Those enrolled in UGA- or Emory-based PharmD residency enrolled at Emory University) research participant programs are also eligible to apply.

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Course Descriptions interested in neuroscience research will round with neurology inpatient CPTR 500 – Fundamentals of consult teams); participating in tertiary Epidemiology (2 credits) and community-based research sites; Introduces the principles and methods observing state-of-the art, hospital- of epidemiology and includes concepts based, analytical technologies; and and methods used for population- shadowing additional multidisciplinary based research. Epidemiologic study inpatient and/or outpatient teams designs and data collection methods caring for patients with disorders or are described as well as approaches to diseases of interest. data analyses. The concepts of bias and confounding are explored with examples 2) Monthly seminars on topics related from the clinical epidemiology literature. to clinical research – Students attend monthly lectures on a variety of topics CPTR 501 – Translation to Clinical related to clinical research including implementing, and disseminating and translational research informatics, Medicine (2 credits) informed consent, working with large community-engaged research. The science and social media, and This is a key component of the CPTR databases, careers in translational content of the course will be connected entrepreneurial training. program. The goal is to provide students research, and regulations in conducting with expertise from MSM, UGA, and with a new set of experiences relevant clinical trials. Emory and will reflect community- MSCR 593 – Ethical, Legal, and Social to both their understanding of disease engagement in urban, rural, and Issues of Responsible Clinical and and their research interest(s) and CPTR 502 – Biostatistics for Clinical disease-based populations. Students Translational Research (1 credit) to illuminate the potential impact Research (2 credits) will have the opportunity to directly Examines concepts inherent to the of high-quality clinical outcomes of Introduces statistical concepts and interact with community-based research ethical and responsible conduct of individuals with disease. This course analytical methods with special partners. The goal is for students to gain clinical and translational research and provides students with both didactic and attention to data encountered in the an understanding of the practice and covers a number of important human experiential learning. This includes: biomedical sciences and biotechnology benefits of community-engaged research. subject research training issues. A as well as translational research. The case-based approach is emphasized. 1) Individualized Clinical Medicine course emphasizes the basic concepts MSCR 592 – Clinical Research Topics include: overview of ethics Rotation – The course instructor of study design including clinical trials, Colloquium (1 credit) and the history of the protection of meets with each student prior to the quantitative analysis of data, probability, This seminar-style course covers a wide- human subjects; informed consent course to discuss the student’s future and statistical inferences. array of practical issues in clinical and and vulnerable subjects; research research career plans and designs a translational research including: misconduct; conflicts of interest; IRB rotation based on the individual needs MSCR 591 – Community Engagement research administration and grants and HIPPA; ethics of genetic testing of the student. Students are linked with and Health Disparities in Clinical and management; federal funding process; and gene therapy; and ethical issues a clinician and clinical investigator Translational Research (1 credit) IRB and HIPPA; conflicts of interest; legal in research in the developing world. working in their area (who may also This course introduces the concepts, aspects of translational research; drug Students are also required to complete serve on their mentoring team). methods, and issues involved in discovery; industry interactions (drug the Emory IRB Human Subjects Experiences may include rounding with community-engaged research. Emphasis discovery and device development); Training Program (online course from a clinical service at Emory-affiliated is given to communication skills and multidisciplinary research and team the Collaborative Institutional Training teaching facilities (e.g., a student practical considerations in planning, science; mentor and mentee training; Initiative [CITI]).

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MSCR 594 A & B – Scientific and Grant in improving health care delivery as well Writing (2 credits) as key tools employed in health services This class is designed to teach those who research and areas of funding (e.g., conduct clinical and/or translational Patient-Centered Outcomes Research research to enhance their scientific and Institute [PCORI], Agency for Healthcare grant writing skills. The course includes Research and Quality [AHRQ]). students from the Emory Master of Science in Clinical Research (MSCR) MSCR 598 – Big Data to Knowledge and CPTR. The material is tailored (BD2K) (1 credit) according to the educational level of This course teaches fundamental Big trainees. Didactics are combined with an Data principles underlying all fields that online learning and face-to-face tutorial incorporate aspects of BD2K and provide format. Everyone works on an individual more detailed case studies within select grant project throughout the semester, clinical patient care fields. More specific but some learning activities take place goals are to: in collaborative groups (e.g., work on • Define Big Data, Data Science, and its specific aims and NIH Biosketch). components Former Morehouse School of Medicine PhD student Patrick Carriere, PhD, who completed the CPTR • Recognize the importance of BD2K in MSCR 595 – Health Services Research numerous sectors of human endeavor (1 credit) and biomedical science Provides students with an understanding • Gain an overall understanding of vari- • Learn how the Big Data Pipeline is ap- team science aspect of clinical and of the nature, methods, scope, magnitude, ous analytics techniques in handling plied in various areas, such as clinical translational research is emphasized and impact of health services research big data informatics, public health informatics, with students working together in and learning health care systems groups in organized class and online activities. MSCR 761 – Introduction to Clinical and Translational Research Other Program Requirements: (2 credits) • Elective Course: Students will Introduces the fundamentals of hu- choose an elective course of at least man subjects research in clinical and 1-credit hour that is relevant to translational research beginning with clinical and translational research. the building blocks of hypothesis • Journal Club meets monthly development, population and study in collaboration with the MSCR sample selection, defining study program and allows interaction with measures, and power and sample size physician-scientists and PhD-level calculations. The course then conducts scientists interested in careers in CPTR student Elyse a broad survey of observational and clinical and translational research. Moran, neuroscience experimental study designs includ- • Attendance at an IRB Meeting PhD student, in Dr. Mar Sanchez’s ing systematic review and meta- at any of the Georgia CTSA Laboratory at Emory analysis. Throughout the semester the partner institutions.

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Georgia Clinical & Translational Science Alliance Research Education Programs GeorgiaCTSA.org/training

CONTACT: Cheryl Sroka Jessica A. Alvarez, PhD, RD Research Education Programs Associate Director, CPTR Georgia CTSA Assistant Professor of Medicine 1599 Building Division of Endocrinology, Metabolism, & Lipids 1599 Clifton Road NE, Emory University School of Medicine Room 6.112 101 Woodruff Circle NE, Room 1313 Atlanta, GA 30322 [email protected] [email protected]

GEORGIA CTSA IS SUPPORTED BY A GRANT FROM THE NIH/NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES (NCATS) UL1TR002378