National Institutes of Health

BY THE NUMBERS: is the nation’s primary medical research agency, supporting research efforts in all 50 states and the District of Columbia. PENNSYLVANIA IN FY 2012* $1.460 Billion: NIH funds awarded “This [NIH] funding will allow us to expand novel (From FY 2003-12, NIH funding in research concepts that we have been developing Pennsylvania totaled $14 billion) to develop a broadly effective seasonal influenza 99: NIH-funded institutions vaccine to protect our population.” 3,369: NIH grants awarded David Weiner, PhD, University of 15**: Cong. districts with NIH grants Pennsylvania School of Medicine * http://report.nih.gov/award/

IMPROVING PENNSYLVANIA’S HEALTH THROUGH NIH FUNDING The University of Pennsylvania received $457 million in NIH grants in FY 2012. Basic science research at the university helped develop the breast cancer drug Herceptin, extending the lives of patients with advanced breast cancer and lowering cancer recurrence rates. NIH also supports research at the University of Pittsburgh, which was awarded $430 million in FY 2012. University investigators developed a biodegradable artery graft that, 90 days after being inserted into rats, is completely replaced by a naturally regenerated artery. Children’s Hospital of Philadelphia ranked second in the U.S. News and World Report Best Children's Hospitals Honor Roll 2012-13 and received $126 million in NIH funding in FY 2012. Researchers discovered 25 new genetic copy number variants associated with autism. Pennsylvania State University and the university’s Hershey Medical Center received NIH grants totaling $111 million in FY 2012. Hershey scientists identified a human protein that the malaria parasite uses to infect cells, which could lead to a vaccine or new therapies.

NIH FUNDING IN SELECTED PENNSYLVANIA DISTRICTS** District Grant total District Grant total District Grant total District Grant total 1 $120,684,223 5 $57,886,011 8 $5,868,854 14 $503,199,388 2 $685,424,804 6 $12,602,961 10 $5,279,822 17 $56,290,167 **District funding data is based on districting for the 112th US Congress

PENNSYLVANIA’S BIOMEDICAL RESEARCH PROFILE The Mellon College of Science at Carnegie Mellon encourages multidisciplinary research in many fields including biomedical science and has employed nine of the university’s 17 Nobel laureates. Eight Pennsylvania universities are categorized by the Carnegie Foundation as having “Very High” or “High” research activity.

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NIH invests $30.9 billion in medical is to seek research to benefit the American people. fundamental knowledge about the nature and behavior of living systems and the More than 80% of NIH funding is distributed application of that knowledge to enhance through approximately 50,000 competitive health, lengthen life, and reduce the burdens grants to more than 300,000 researchers at of illness and disability. more than 2,500 universities and other institutions throughout the US. http://www.nih.gov/about/mission.htm

INVESTMENT IN NIH RESEARCH BENEFITS THE PENNSYLVANIA ECONOMY Pennsylvania is home to 2,240 bioscience business establishments.1 From FY 2004-09, NIH awarded $445 million to Pennsylvania companies,2 and venture capital firms invested an additional $2.95 billion in bioscience firms during this period.3 Since 1996, University of Pittsburgh innovation has led to the formation of 89 start-ups.4 Pennsylvania residents held 81,796 bioscience industry jobs in 2010. In Pennsylvania, the 2010 average annual wage was $90,704 for bioscience sector workers compared to the private sector average of $45,323.1

“Already, our Penn State Clinical and Translational Science Institute (CTSI) is bringing together researchers from across the University’s colleges, campuses, programs and departments and fostering collaborative research. This CTSA funding award [from NIH] will add to this momentum and substantially increase our infrastructure for supporting translational research, expanding our ability to take scientific progress from the lab bench to the patient’s bedside.” Harold L. Paz, MD, CEO, Penn State Hershey Medical Center and Health System

NIH SPURS PENNSYLVANIA INNOVATION Pennsylvania received $53 million in NIH grants in FY 2012 to train the next generation of innovative scientists.2 Fifty-two Pennsylvania businesses received NIH funding totaling $33 million in FY 2012 for the research and development of technologies with potential commercial applications.2 From 2004-09, 5,041 bioscience-related patents were issued to individuals and entities in Pennsylvania, with drugs and pharmaceuticals representing the largest category.3 A total of 843 clinical trials were initiated at Pennsylvania institutes in 2009.3

1 Battelle/BIO 2012 State Bioscience Industry Development Report 3 Battelle/BIO 2010 State Bioscience Initiatives Reports 2 NIH Research Portfolio Online Reporting Tools (RePORT) 4 University of Pittsburgh OTM, 2012 Annual Report

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