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RIKEN Center for Developmental 2-2-3 Minatojima-minamimachi, Chuo-ku, 650-0047, TEL : +81-78-306-0111 FAX : +81-78-306-0101 E-mail : [email protected] http://www.cdb.riken.jp/en/

RIKEN Center for Developmental Biology

Access To

To Sannomiya (Downtown Kobe) Kobe City Medical Center Local train lines General Hospital IBRI JR, , Hanshin train lines → Sannomiya Station Iryo Center Stn. (Shin-Kobe Station) Shin-Kobe Station → RIKEN Center for RIKEN Center for Sannomiya Station (via ) (2 min.) Developmental Biology Life Science Technologies (CDB) (CLST) limousine bus from local RIKEN Integrated Itami () Airport → Sannomiya (40 min.) Innovation Building Kansai International Airport (KIX) → Sannomiya (65–75 min.) RIKEN Advanced Institute for Computational Science (AICS) (IIB)

From Sannomiya to the CDB Mae Stn.

By Port-liner monorail Port-liner Sannomiya Station → Iryo Center Station (12 min.) Take the train bound for . By taxi From Shin-Kobe Station → CDB (25 min.) From Sannomiya → CDB (20 min.)

Kobe Airport

Kobe Airport Stn.

RIKEN 2016-045 (09.2017)

CDB Organization

CDB Budget Center Director Hiroshi Hamada From Japanese Government (FY2017) Cellular Environment and Response Organogenesis Research Program Administrative and Research Deputy Director other expenses expenses Research Program Labs in this program study mechanisms underlying the formation of complex model systems, in the hopes of gaining insight into the bases 177 246 This program includes labs focused on developing platforms for gaining a better of the higher order structure of organs and functional development. understanding of fundamental control principles of animal development, aimed Office of the Director at learning new ways of overcoming developmental disorders. Cell Adhesion and Tissue Patterning Total Morphogenetic Signaling Masatoshi Takeichi Research Ethics Shigeo Hayashi 1,362 Education Officer Cell Asymmetry Growth Control Signaling Fumio Matsuzaki Personnel Takashi Nishimura expenses Advisory Council Neocortical Development 939 (million yen)* Chromosome Segregation Carina Hanashima Tomoya Kitajima In addition to the dedicated funds outlined above, Sensory Circuit Formation individual labs and investigators are encouraged to Takeshi Imai compete for external funding as well, from sources Developmental Epigenetics such as the Japan Society for the Promotion of Science Ichiro Hiratani About CDB (JSPS), the Japan Science and Technology Agency The RIKEN Center for Developmental Biology was Epithelial Morphogenesis (JST), and other governmental and private sources. launched in April 2000 to conduct research into Vascular Morphogenesis Yu-Chiun Wang These external funds represent a signi cant development and regeneration, key scienti c Li-Kun Phng component of the Center’s total funding every year. foundations in addressing many of the greatest Comparative Connectomics challenges in biomedicine and advancing the External Funds (FY2016) frontiers of human knowledge. The Center is Heart Regeneration Kazunari Miyamichi located within a dynamically growing biomedical Wataru Kimura Others Grant-in-Aid for research park in Kobe, Japan, nearby to many (Foundations, Scienti c Research other research and medical centers, including the Developmental Biology and Private Industry, etc. ) (MEXT) RIKEN Center for Life Science Technologies, RIKEN Stem Cells and Organ Regeneration Mathematical Science Program Advanced Institute for Computational Science (K 426 325 This program aims to develop a systematic understanding of the complex computer), and Kobe City Medical Center General Research Program cellular interactions underlying tissue morphogenesis through quantitative Hospital. The CDB also bene ts from belonging to Labs in this program work on identifying methods for controlling organ mathematical approaches and the development of computational models RIKEN, Japan’s largest and most comprehensive formation and regeneration through the study of stem cells and organogenesis. of gene expression, signal modulation, and dynamic processes. research organization for basic and applied Total science as well as its close ties to graduate schools Organ Regeneration and research institutes in Japan and other Takashi Tsuji Axial Pattern Dynamics 1,403 countries, giving our scientists access to a broad Hidehiko Inomata network of talent and technology across the country and around the world. Lung Development Grants Mitsuru Morimoto Organismal Patterning Kobe Biomedical Innovation Cluster: (JST, etc.) Hiroshi Hamada http://www.kobe-bic.org/english/index.html 652 * Tissue Microenvironment (million yen) *1 million yen≈10,000 USD Hironobu Fujiwara Technical Development and Supporting Program CDB Staff Numbers in vitro Histogenesis This program aims to develop new technologies that meet the Laboratory heads 18 research needs of CDB and provide technical support to labs using Mototsugu Eiraku Deputy leaders 2 these technologies. Research scientists 59 Research associates 3 Human Organogenesis Single-cell Omics Research Unit Technical sta 67 Minoru Takasato Itoshi Nikaido Assistants 16 Visiting scientists 141 Student trainees 31 Research and Development Project Collaboration Centers Program Part-time sta 23 This program conducts research using induced pluripotent (iPS) and other This program aims to facilitate collaborations with industry by Other 12 types of stem cells to develop approaches to regenerate retinal function, in pursuing longer term projects in areas related to neurodegenerative active collaboration with the University Center for iPS Cell Research and kidney diseases, with a view to develop seeds of innovation that Total 372 and Application (CiRA) and various Kobe-based research initiatives. can be translated into practical applications. Kobe Branch administration 85 RIKEN CDB–Otsuka Pharmaceutical (as of August 2017) Retinal Regeneration Collaboration Center Masayo Takahashi Hiroshi Hamada 4 5