Hans Zinsser: a Tale of Two Cultures

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Hans Zinsser: a Tale of Two Cultures YALE JOURNAL OF BIOLOGY AND MEDICINE 72 (1999), pp. 341-347. Copyright © 2000. All rights reserved. ORIGINAL CONTRIBUTION Hans Zinsser: A Tale of Two Cultures William C. Summers Yale University School of Medicine, New Haven, Connecticut Hans Zinsser, president ofthe Society ofAmerican Bacteriologists in 1926, was known as muchfor his literary and textbook writing asfor his scientific contributions. He was a widely known scien- tist andperson ofletters. His early interests in poetry and otherforms ofliterature were maintained and developed during his career as a microbiologist, and his most enduring legacy is based on his writing about microbiologyfor a general readership as well as his reflective andphilosophical auto- biography. Hans Zinsser (1878-1940) was presi- there have always been people, with erudi- dent of the Society of American Bacteriol- tion, learning and talent to spare, who have ogists in 1926. At that time, he was 48 made their marks in both science and the years old and Professor of Bacteriology arts: recall that science was Goethe's day- and Immunology at Harvard Medical job; Alexandr Borodin was a famous clin- School (Figure 1). It is likely that Zinsser ical chemist; and Arthur Conan Doyle was is one of the few early Society presidents a family physician. Perhaps even Steven J. whose name is still recognized by current Gould of our own time will be remem- students of microbiology. Such fame may bered for his graceful stories of living result from some astounding discovery, things long after his theory of punctuated such as Oswald Avery's work on trans- equilibrium is on the dust heap of history, forming DNA; or because of eponymic replaced by newer versions of the truth. immortality such as Rebecca Lancefield's While Hans Zinsser is not the record- immunological classifications; or because holder for authorship of the most durable of authorship of enduring works of schol- textbook, his Text Book of Bacteriology, arship or pedagogy, such as the case for first published in 1911 with Philip Hanson David Bergey and his Manual ofDetermi- Hiss, is still current in its 20th edition, native Bacteriology. Hans Zinsser's mem- published in 1992, under the editorship of ory lives on for this latter reason: he was a a distinguished group of microbiologists gifted writer of both textbooks and literary [1]. His 1914 text Infection and Resistance works. Today we marvel at individuals went through five editions, the last one who bridge C.P. Snow's Two Cultures, but published in 1939 with coauthors John F. a To whom all correspondence should be addressed: William C. Summers, Yale University School of Medicine. 333 Cedar St. New Haven, CT 06520-8040. Fax: 203-785-6309; E- mail: [email protected]. 341 342 Summers: Hans Zinsser Figure 1. Hans Zinsser (1878-1940). Photograph courtesy of American Society of Micro- biology. Enders and LeRoy D. Fothergill [2]. Hans Zinsser was born in 1878 in New Clearly, Zinsser had a gift for the written York city into a liberal German family with word. close ties to the socialists involved in the Hans Zinsser represents an increas- 1847 uprisings in Germany". Indeed, ingly rare intellectual tradition, that of Zinsser's father, an entrepreneurial indus- amateurism. Not amateur in the modem trial chemist, is buried next to Carl Schurz, sense of bumbling incompetence, but ama- one of the great German-American leaders teur in its older etymological sense, that is of his time. Hans was raised in a home of for doing something for the pure love of it. intellectual culture and privilege, with He was a scientist without a Ph.D; he was summers in Europe, private tutors, a-rd the a writer without having lived in Blooms- time and tranquility to leam to ride well, to bury; and he was an educator and leader play the violin, and to become fluent in simply by his own nature. several languages. In due course, he attend- In this brief review, I will consider ed Columbia University and concentrated Zinsser's work in what we (artificially, I his studies in the Comparative Literature think) divide into two domains of thought: department. He was particularly influenced science and literature. It is in the latter by the professor in that department, George domain, I would suggest, that Zinsser Woodberry, and a year after graduation, made his lasting contributions. Zinsser and a close friend, William A. b A general reference on Zinsser's life is found in The Biographical Memoirs ofthe National Acad- emy of Sciences [3]. Summers: Hans Zinsser 343 Bradley (1878-1939) published a small embryology of the mouse, and he also did book of their poems and dedicated the vol- extra work in bacteriology. His first scien- ume to Woodberry [4]. tific publication, it seems, was in 1903, the How Hans came to science from such year of his graduation from medical literary beginnings is described in his school, and was on the effect of radium autobiography (although one must be sus- emanations on bacteria. He obtained a picious of such memories of the elderly position as house physician at Roosevelt trying to make some logical sense of their Hospital in New York City, and after two youth, I suggest we accept this account years there, he joined a classmate in a with that caveat): small private practice of general medicine In my sophomore year, while in the Woodber- in New York. Again, in his own words (in rian poetic exaltation, and feeling much of the the third person): time like a young Shelley, I threw a snowball . .,,finding that there was no competitive across the campus at a professor emerging demand for his talents in any of the medical from the Natural Science Building. It was a laboratories, [he] established himself, for a prodigious shot, a good hundred yards, I time, as a practitioner in New York. He was think. I hit him in the ear, knocked his hat off, not a success, though the experience did a and had the time to disappear around the cor- great deal to develop his judgement. Yet his ner. I had nothing against him. It was an heart was never in practice. From the very impulse, and a happy one, because I became beginning, he retained a place for work in the guiltily conscious of him, thereafter, and laboratories of the College of Physicians and eventually I took one of his courses as a sort Surgeons, where he was usually to be found of apologetic gesture . and it was he who when some patient asked for him. When he awakened in me the realization of the philo- was telephoned for and conscientiously sophical implications of scientific fact. There rushed to his office, he was so obviously were great teachers of science at Columbia in annoyed by the interruption that few tried him those days, and the junior year - largely more than once. That sort of thing doesn't owing to the inspiration of the man whom I help" [5, p. 154]. had hit in the ear - found me, without cutting loose from the Department of Comparative Fortunately for Zinsser, for he report- Literature, feeling as though I had suddenly ed income of $1,100, against expenses of entered a new world of wonders and revela- $6,000 that year, he was offered a full-time tions, on the top floor of Schermerhorn Hall job at Columbia in 1908 as Instructor in under the reign of Edmund B. Wilson, and Bashford Dean [5, pp. 47-48]. Bacteriology. This was a busy period: he published the first edition of the Text Book Such random events and contingen- of Bacteriology with Philip Hanson Hiss, cies, of course, are what determine the Jr., with whom he also worked on the role courses of our lives, contrary to the beliefs of "leukocytic extracts" on infections. of many of my always anxious and over- Zinsser's reputation was growing so that in programmed young friends. 1910 he was offered, and accepted, the The practical necessity of a career Headship of the Department of Bacteriol- which provided a livelihood appeared to ogy at Stanford University. He went to be the main consideration that led Zinsser Stanford with some trepidation, however, to enter medical school at Columbia in because of the admonition of Jacques 1899. Opportunities for a paying job as a Loeb, the famous biologist from the Rock- scientist were uncertain at best, but medi- efeller Institute, against the flamboyant cine might allow him to follow his inter- president of Stanford, David Starr Jordan. ests in science while still earning a living. Loeb counseled Zinsser: While in medical school he completed a A man of your temperament will stand it thesis for the M.A. degree on the early about six months. Then you will come to me 344 Summers: Hans Zinsser to help you get anotherjob. But if you wish to role of these proteose-like substances in be a success at Stanford, work on fish. Jordan himself, when he works at all, works on fish. immunological reactions. He counts the scales on their behinds. [every- Through the work of Michael Heidel- one] works on fish. The geologists, the berger and Oswald Avery, we now know palaeontologists, the botanists, the English these residue antigens as polysaccharides. Department, the Romance Languages Depart- His work on syphilis was not directly suc- ment, even the philosophers - they all work cessful in his effort "to take the danger out on fish. Go there my boy, be happy, and work of love" [6], and he was only partly suc- on fish - or, at least, if you are too honest for straight fish, work on the bacteria you can cessful in paving the way to a successful find in fish.
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