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2005-2016 [CURRICULUM VITAE] ١ Education: Position 2006-2009 Instructor in Shiraz University of Medical Sciences 2010-201

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2005-2016 [CURRICULUM VITAE] ١ Education: Position 2006-2009 Instructor in Shiraz University of Medical Sciences 2010-201 2005-2016 [CURRICULUM VITAE] Name: Khosravi Ayyoob Birth Date: 1980, march 21 Marital status: Married Address: Golestan University of Medical Sciences, Faculty of Advanced Medical Technologies E-mail address: [email protected] Telephone: Office: +98-17-32425995 Education: Degree Date Major University Ph.D 2011- 2016 molecular medicine Golestan University of Medical Sciences, Gorgan M.Sc 2002-2005 Cell and Molecular Biology Imam Hussein University, Tehran B.Sc 1998-2001 Biology Shahid Beheshti University, Tehran Position 2006-2009 Instructor in Shiraz University of Medical Sciences 2010-2011 Instructor in Golestan University of Medical Sciences 2016- … Assistant professor in Golestan University of Medical Sciences Research interests Molecular Medicine (Cancer biology, Human Cancer Stem cell and Human genetic) Medical biotechnology (Cell Line Development & Engineering) Specialized techniques: 1-Molecular biology: - DNA and RNA extraction (from Humans, Bacteria and Viruses) - PCR (Nested PCR, RT-PCR, ARMS-PCR and Real time-PCR) -Horizontal (agarose) and vertical Electrophoresis (PAGE) - SDS-PAGE -SSCP (single strand conformational polymorphism) -Gel extraction and purification of PCR product - DNA cloning ١ 2005-2016 [CURRICULUM VITAE] - RFLP (restriction fragment length polymorphism) - DNA typing by Short Tandem Repeats (STRs) -construction of DNA typing ladders 2- Molecular virology: - Quantification of HIV, HBV and HCV genes by Real-time PCR - PCR detection and genotyping of HIV, HBV and HCV viruses 3-Immunology: - ELISA (Enzyme-linked immunosorbent assay) - Western blot - Indirect Immunofluorescent Assay (IFA) - Immunocytochemistry (ICC) 4- Cell Culture: - Basic animal cell culture - Primary culture of Human Cancer Cells - Cancer stem cell biology Teaching experiences Course Location (University) Level Date cell and molecular biology Shiraz university of medical B.Sc of experimental 2008 sciences sciences Biosafety principles in Shiraz university of medical B.Sc of experimental 2008 laboratory practices sciences sciences cell and molecular biology Shiraz university of medical B.Sc of experimental 2009 sciences sciences Biosafety principles in Shiraz university of medical B.Sc of experimental 2009 laboratory practices sciences sciences cell and molecular biology Shiraz university of medical B.Sc of experimental 2010 sciences sciences Biosafety principles in Shiraz university of medical B.Sc of experimental 2010 laboratory practices sciences sciences Medical genetics Shiraz university of medical B.Sc of experimental 2010 sciences sciences ٢ 2005-2016 [CURRICULUM VITAE] Molecular genetics methods Golestan University of MSc of medical genetic 2011 Medical Sciences cell and molecular biology Golestan University of B.Sc of experimental 2011 Medical Sciences sciences Molecular diagnosis of Golestan University of Ph.D of molecular 2011 Medical Sciences diseases medicine genetic engineering Golestan University of MSc of medical genetic 2011 Medical Sciences Molecular genetics methods Golestan University of MSc of medical genetic 2012 Medical Sciences cell and molecular biology Golestan University of B.Sc of experimental 2012 Medical Sciences sciences genetic engineering Golestan University of MSc of medical genetic 2013 Medical Sciences genetic engineering Golestan University of MSc of medical 2013 Medical Sciences biotechnology genetic engineering Golestan University of MSc of medical genetic 2013 Medical Sciences Language Skills Persian and English Computer Knowledge Well in science-related softwares such as DNAsis, Oligo, GENE RUNNER, SPSS, PHYLIP, Endnote, SNPStats, ImageJ and... Research projects: 1- Title of the Project: characterization of human immunodeficiency virus type-1-infected plasma by near-infrared Spectroscopy Kind of Cooperation: as main co-worker Year: 2006-2007 2- Title of the Project: Analysis of the correlation between IL-18 promoter polymorphisms, IL-18 and IgE serum levels in asthmatic patients. Kind of Cooperation: as main co-worker Year: 2007-2009 ٣ 2005-2016 [CURRICULUM VITAE] 3- Title of the Project: Investigation of matrix metalloproteinase polymorphisms and relation to common cancers in Fars province. Kind of Cooperation: as main co-worker Year: 2008-2009 4- Title of the Project: Interleukin-1α (IL-1 α) and interleukin-1 receptor antagonist (IL- 1RN) gene polymorphisms in MS patients and healthy individuals Kind of Cooperation: as executive of project Year: 2011-2012 5- Title of the Project: Association of torsade de pointes with Allelic variants of long QT syndrome genes in Iranian population Kind of Cooperation: as executive of project Year: 2011-2012 6- Title of the Project: Computational prediction of the effects of coding single nucleotide polymprphisms in human endothelial nitric oxide synthase gene Kind of Cooperation: as executive of project Year: 2011-2012 7- Title of the Project: Association of polymorphisms in MCP-1 promoter variant –2518 and Interferon gama +874 T/A with suscepbility to pulmonary tuberculosis in Golestan province, Iran Kind of Cooperation: as executive of project Year: 2011-2012 8- Title of the Project: Characterization of transcriptional co-activator (TAZ) as a candidate cancer stem cell marker in esophageal Squamous Cell Carcinoma (ESCC) Kind of Cooperation: as executive of project Year: 2013-2015 9-Title of the Project: Invesgaon of Th1, Th17 and T reg cells frequency in esophageal cancer patients and their association with mir155, mir21, mir106a, mir29b and TGF-β plasma level Kind of Cooperation: as executive of project Year: 2016-2017 ٤ 2005-2016 [CURRICULUM VITAE] publications: 1- Mirza Khalil Bahmani, Ayyoob Khosravi, Fereidoun Mahboodi, Ramin Sarrami- Forooshani.Genotypic correlates of a virologic response to Lamivudine, Stavudine and Nevirapine in patients whom combination therapy had failed. Iranian journal of Infecous Disease, 2008; 3(4):215-219. 2- Mirza Khalil Bahmani, Ayyoob Khosravi, Ramin Miri, Yukie Iwabu, Kazuyoshi Ikuta and Akikazu Sakudo. Spectroscopic characterization of human immunodeficiency virus type-1-infected plasma by principal component analysis and soft independent modeling of class analogy of visible and near-infrared spectra. Molecular Medicine REPORTS, 2009; 2: 805-809. 3- Mirza Khalil Bahmani, Ayyoob Khosravy, Adel Mobasser, Islam Ghezelsofla. Seroprevalence of Hepatitis B Virus (HBV) Infection and Vaccination Compliance among Health Care Workers (HCWs) in Fars Province, Iran. Iranian journal of Infecous Disease, 2010; 5(1):45-50. 4- Rahimi A. A, Bahmani M. Kh, Masoudnejad A, Sa’adati M, Khosravi A. Shafi’khani A, Mohammadzade J. Application of near-infrared spectroscopy and support vector machine in detection of HIV-1 infecon. Kowsar Medical Journal 2010; 15 (1): 23-29. 5- Ayyoob Khosravi, Mirzakhalil Bahmani, Islam Ghezel-Sofla. Co-Infection by Hepatitis C Virus in human immunodeficiency virus Infected Patients in southwest of Iran. Iranian journal of Infectious Disease. 2010; 5 (4):223-227. 6- Samaneh Hajihoseini, Mirza Khalil Bahmani, Ayyoob Khosravi. Eslam Ghezelsofla, Abbas Ghaderi. Prognostic significance of MMP2 and MMP9 functional promoter single nucleotide polymorphisms in Head and Neck squamous cell carcinoma. Iranian Journal of Basic Medical Sciences. 2011; 14(2):137-144. 7- Faranak Mahmoudi Alami, Mehran Ahmadi, Hamidreza Bazrafshan, Alijan Tabarraei, Ayyoob Khosravi, Mohammad Amin Tabatabaiefar and Nader Mansour Samaei. Association of the TCF7L2 rs12255372 (G/T) variant with type 2 diabetes mellitus in an Iranian population. Genet Mol Biol, 2012; 35(2): 413–417. 8- Faranak Mahmoudi Alami, Nader Mansour Samaei, Mehran Ahmadi, Alijan Tabarraei, Ayyoob Khosravi, Mohammad Amin Tabatabaiefar and Seyyede Naemeh Javid. Associaon of Transcripon Factor 7-Like 2 (Tcf7l2) Gene Haplotypes with ٥ 2005-2016 [CURRICULUM VITAE] the Risk of Type 2 Diabetes Mellitus in Iran. Advances in Biological Research 7 (5): 145-150, 2013. 9- Ghezelsofla E, Tabaraee B, Aghamolaee H, Harzandi N, Sabokbar A, Zamani M, Khosravi A. Optimization of PCR assay for artificially contaminated serum samples as a model for Rapid laboratory confirmation of human brucellosis. Iranian Journal of Infectious Diseases and Tropical Medicine. 2013; 18(61):15-20. 10- Ayyoob Khosravi, Bita Javan ,MohammadAminTabatabaiefar, Hamid Ebadi, Davood Fathi, Majid Shahbazi. Association of interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population. Journal of Neuroimmunology 288 (2015) 114–119. 11- Ayyoob Khosravi, Masoud Khoshnia, Vahideh Kazeminejad, Jahanbakhsh, Asadi (2015). Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method. Tumor Biology: 1-8. DOI 10.1007/s13277-015-4133-4. 12- Pedram Torabian, Ayyoob Khosravi, Mehdi Zahedi, Haghjoo Majid, Mehdi Gholizadeh , Vahid Khori. Lack of associaon between KCNE2 gene variants and the congenital long QT syndrome in Iranian population. Physiology and pharmacology journal (accept-2016). International conference abstracts: 1- Khosravi Ayyoob, Tavallaii Mahmood, Zeinali Sirus, Sajjadian Abdollah, 2005. Constructing VWA allelic ladder by molecular cloning method for DNA typing purpose. Seoul Korea, ICML 2005. 2- Sajjadian Abdollah, Khosravi Ayyoob, Tavallaii Mahmood, Zeinali Sirus, 2005. Construcng THO1 allelic ladder by molecular cloning method for DNA typing purpose. 12th European congress on Biotechnology, August 21-24, 2005. 3- Mirza Khalil Bahmani, Ayyoob Khosravi, Rahele Sheikhi, Fereidoun Mahboodi,
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