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Tomo 34 (1-2): 7-365. 2009 KURTZIANA

Medicinal : A general review and a and ethnopharmacological screening of the native Argentine Flora

Gloria E. Barboza 1, 3, 4, Juan J. Cantero 2, César Núñez 2, Adriana Pacciaroni 1, 3 & Luis Ariza Espinar 1

1 Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Casilla de Correo 495, 5000, Córdoba, . 2 Departamento Biología Agrícola, Facultad de Agronomía y Veterinaria, Universidad Nacional de Río Cuarto, Ruta Nac. 36 - Km. 601 - Código Postal X5804BYA, Río Cuarto, Córdoba, Argentina. 3 Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Avda. Haya de la Torre y M. Allende s.n., Córdoba, Argentina. 4 Autor para la correspondencia: [email protected].

Summary Barboza, G. E., J. J. Cantero, C. Núñez, A. Pacciaroni & L. Ariza Espinar. 2009. Medicinal Plants: A general review and a phytochemical and ethnopharmacological screening of the native Argentine Flora. Kurtziana 34 (1-2): 7-365. A review and a checklist based on empirical evidence of the therapeutic properties of the native medicinal flora from Argentina are presented. The chemical constituents and biological activity of each species, when known, are also provided. Medicinal flora comprises 1,529 taxa of vascular plants (Pteridophyta: 56; Gymnospermae: 13; Monocotyledoneae: 152; Dicotyledoneae: 1,308), including 115 endemic species. In addition, the distribution of these species is analyzed, and the endemic areas are also stated. Key words: Flora medicinal, Argentina, review, folk medicine, diversity, endemisms.

Resumen Barboza, G. E., J. J. Cantero, C. Núñez, A. Pacciaroni & L. Ariza Espinar. 2009. Plantas medicinales: Revisión y "screening" fitoquímico y etnofarmacológico de la flora nativa de Argentina. Kurtziana 34 (1-2): 7-365. Se presenta una revisión y se provee un catálogo de la flora medicinal nativa de Argentina basado en el conocimiento empírico de las propiedades terapéuticas de las especies. Se complementa con la composición química y actividad biológica para cada especie cuando la información está disponible. Se reportan 1529 taxones medicinales de plantas vasculares (Pteridófitas: 56; Gimnospermas: 13; Monocotiledóneas: 152; Dicotiledóneas: 1308), incluidas 115 especies endémicas. Además, se realiza un análisis de la distribución de estas especies y se determinan las áreas de endemismos. Palabras clave: Flora medicinal, Argentina, revisión, medicina popular, diversidad, endemismos. 8 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

Introduction and was discovered independently by residents of both the New and Old worlds as a remedy for Plants have provided man with all his needs aches and fevers (Raskin et al., 2002). Medicinal in terms of shelter, clothing, food, flavours and plants have contributed to humanity’s health care, fragrances as not the least, medicines. Plants source of livelihood cultural traditions, and have formed the basis of sophisticated financial gains, among others (Hamilton, 2004). Traditional Medicine (TM) systems that have However, medicinal plants are constrained by been in existence for thousands of years and procedures such as classification, identification, continue to provide mankind with new remedies. and characterization. Some of the oldest known medicinal systems Some 80% of the world’s population still of the world such as Ayurveda of the Indus relies upon plants for primary health care; even civilization, Arabian medicine of Mesopotamia, today in Western medicine, and despite progress Chinese and Tibetan medicine of the Yellow in synthetic chemistry, some 25% of River civilization of China and Kempo of the prescription medicines are still derived either Japanese are all based mostly on plants. The directly or indirectly from plants (Farnsworth ancient cultures are known for their systematic & Soejarto, 1991). Nearly 50,000 species of collection of information on herbs and their rich higher plants have been used for medicinal and well-defined herbal pharmacopoeias. purposes. They are also used in food, cleaning, Although some of the therapeutic properties personal care and perfumery. In systems of attributed to plants have proven to be erroneous, traditional healing, major pharmaceutical drugs medicinal therapy is based on the have been either derived from or patterned after empirical findings of hundreds and thousands compounds from biological diversity (Bisset, of years (Gurib Fakim, 2006). 1994). A trend in phytomedicine is the use of According to OPS (Arias, 1999) a medicinal new plant origin bioactive compounds with the plant is (1) any plant used in order to relieve, potential for chemical modification, which will prevent or cure a disease or to alter broaden phytomedical importance. Molecular physiological and pathological process, or (2) biology is also being used in this process and any plant employed as a source of drugs or the pharmacological profiles of these their precursors. A phytopharmaceutical compounds are screened using new research preparation or herbal medicine is any equipment and new technology (Cordell, 2000; manufactured medicine obtained exclusively Cordell & Colvard, 2005; Yaniv & Bachrach, from plants (aerial and non-aerial parts, juices, 2005; Pieters & Vlietinck, 2005). resins and oil), either in the crude state or as a The use of plants in medicines ranges from pharmaceutical formulation (Rates, 2001). crude preparations or extracts, to refined There is ample archaeological evidence extracts and single molecular species. In terms indicating that medicinal plants were regularly of categories of use this encompasses food employed by people in prehistoric times. In supplements, herbal medicines, botanical drugs several ancient cultures botanical products were and prescription medicines. Increased interest ingested for biomedically curative and in plants as a source of novel pharmacophores psychotherapeutic purposes (Halsberstein, 2005). recognizes their chemical diversity and Knowledge of medicinal plants has usually versatility, not matched by synthetic chemistry resulted from trial and error methods, and often libraries. In spite of the surge of activity in based on speculation and superstition (Hamayun synthetic chemistry over the last 20 years or so, et al., 2006). The strong historic bond between almost half the some 850 small molecules plants and human health began to unwind in introduced as drugs were derived from plant 1897, when Friedrich Bayer and Co. introduced sources. Over 100 small molecules derived synthetic acetyl (aspirin) to the either directly or indirectly from plants are world. Aspirin is a safer synthetic analogue of currently at some point in the clinical trials salicylic acid, an active ingredient of willow bark, process (Fowler, 2006). BARBOZA, G. E. et al. Medicinal flora of Argentina 9

The beneficial medicinal effects of plant The pharmaceutical and biotechnological materials typically result from the combinations industries are much interested in using this of secondary products present in the plant. That knowledge for the discovery, development the medicinal actions of plants are unique to and application, within biodiversity, of new particular plant species or groups is consistent active products on health and new genes with with this concept as the combinations of properties for food improvement (Heinrich & secondary products in a particular plant are Gibbons, 2001). In recent years, the plant often taxonomically distinct (Kaufman et al., remedies used in TM – both in traditional 1999). Ecological function of secondary herbal medicine and in shamanic healing- products may have some bearing on potential have received considerable attention for medicinal effects for humans. For example, ethnobotanist, and today the chemistry and secondary products involved in plant defense pharmacology of many of these are well through cytotoxicity toward microbial understood (Cotton, 1997). Chemical analyses pathogens could prove useful as antimicrobial and biological assays have begun to play an medicines in humans, if not too toxic (Briskin, important part in ethnobotanical studies and 2000). In contrast to synthetic pharmaceuticals there are now numerous examples where based upon single chemicals, many scientific analyses have provided objective phytomedicines exert their beneficial effects evidence to validate traditional plant use, for through the additive or synergistic action of example Homalanthus nutans (G. Forst.) several chemical compounds acting at single Guill. (Euphorbiaceae), used by samoan or multiple target sites associated with a healers against the viral disease yellow fever; physiological process. This synergistic or extracts have been found to exhibit potent additive pharmacological effect can be antiviral activity, particularly against the beneficial by eliminating the problematic side human immunodeficiency virus HIV-1 effects associated with the predominance of a (Balick & Cox, 1996). As new uses of single xenobiotic compound in the body (Tyler, medicinal plants are discovered and 1999). popularized, the concern for sustainability is Ethnobotanical studies have become being increasingly addressed; concern over increasingly valuable in the development of the growth in biopiracy also combines with health care and conservation programs in the critical need for the conservation of different parts of the world. The green species and their habitat (Science Reference pharmaceuticals are receiving extraordinary Services, 2008). importance and popularity. Ethnobotany and The search for new molecules, nowadays, has ethnopharmacology have contributed to the taken a slightly different route where the science discovery of many important plant-derived of ethnobotany and ethnopharmacognosy are drugs. Soejarto et al. (2005) claimed that future being used as guide to lead the chemist towards mass bioprospecting effort must incorporate different sources and classes of compounds important consideration about team scientific (Gurib-Fakim, 2006). Plant derived natural expertise (of all relevant disciplines) together products hold great promise for discovery and with expertise in a wide range of human development of new pharmaceuticals endeavors, including diplomacy, international (McChesney et al., 2007). laws and legal understandings, social sciences, Since ancient times, medicinal plants have politics, anthropology and good common been harvested from the wild (Mshigeni et al., sense. 1991; Balick & Cox, 1996; Sheldon et al., 1997; Development of medicinal plants relies Dhillion & Ampornpan, 2000; Singh & very heavily on the knowledge carried by Padmalatha, 2004). In many rural communities, indigenous peoples and rural societies. traditional medicine (TM) is still viewed as the Herrera Vasquez & Rodríguez Yunta (2004) mainstay of primary health care systems argued the importance of taking account of (Bannerman et al., 1983; Manandhar, 1994; indigenous knowledge or «ethnoknowledge». Svarstad & Dhillion, 2000; Manandhar, 2002) 10 Tomo 34 (1-2): 7-365. 2009 KURTZIANA due to its effectiveness, cultural preference or Büttel 1996). In Japan, 60–70% of allopathic absence of «modern» alternatives (Plotkin & doctors prescribe TM for their patients, and in Famolare, 1992; Taylor et al., 1995; Balick et China, TM accounts for about 40% of all health al., 1996; Tabuti et al., 2003). care. Forty-eight percent of the populations in TM is a comprehensive term which Australia, 70% in Canada, 42% in the US, 38% describes medical knowledge systems such as in Belgium and 75% in France, have used TM the traditional Chinese, the Indian ayurveda, the at least once. In the United Kingdom, almost Arabic unani, or other forms of indigenous or 40% of all general allopathic practitioners offer folk herbal medicine. In countries where the some form of TM referral or access (Bussmann prevailing health care system is largely & Sharon, 2006). A similar situation exists in dependent on allopathic medicine, or where TM Latin America, where large volumes of has not yet been incorporated to meet national medicinal plants are sold in urban markets health care needs, TM is often referred to as (Shanley & Luz, 2003). Regional Office for «complementary», «alternative» or «non- the Americas (AMRO/PAHO) reports that 71% conventional» (WHO, 2002). of the populations in and 40% of the population in use TM. It is well established that this type of health knowledge and practice plays a fundamental role Current research in drug discovery from in the health programs of developing countries. medicinal plants involves a multifaceted Indeed, for centuries TM has been in certain approach combining botanical, phytochemical, communities the unique health care system biological, and molecular techniques. In order available for the prevention and treatment of to understand the biological activity of a plant, diseases. In addition, there has been an be it medicinal, poisonous, or nutritive, it is increasing awareness and understanding of the necessary to know its chemical constituents. potential of herbal knowledge for discovering Thus, they are plant secondary and primary newer treatments, and for gaining insights into metabolites (e.g. alkaloids, terpenoids, the socioeconomic, conservationist and cultural phenolics, gums, mucilages, carbohydrates, components of society (Alves & Rosa, 2007). amino acids, proteins, fatty acids, glycolipids, etc.) that organize medicinal plants (Croteau et Nonbiomedical healing systems vary across al., 2000). cultures but conceptually they often focus on balance and harmony, which may be treated Knowledge of plant bioactivity has been mentally, physically, or spiritually (Bodeker accumulated by experimentation over centuries 1994; Hewson, 1998; O’Connor, 1998), that is by people living in intimate association with their they favor a «holistic» approach aiming at a environment. Therefore, ethno-directed research systemic model where multiple biological, is very useful in drug discovery and development psychological and social dimensions are (Cox & Balick, 1994; Heinrich & Gibbons, interlinked, often in combination with the 2001). However, accelerated acculturation is patient’s active participation in their own healing disintegrating ethnopharmacological information and recovery (McGaw et al., 2005). Biomedical often faster in many areas than the extinction of treatment systems are often conceptually plant species, which rampant deforestation different than traditional systems focusing on invariably entails (Sanz-Biset et al., 2009). This Cartesian dualism, where body and mind are problem is particularly serious in the tropical treated separately and technological and surgical rainforests (Plotkin & Famolare, 1992). Soejarto procedures are often used for the treatment of & Farnsworth (1989) stress the special physical diseases (Bodeker, 1994; Hewson, significance of these tropical areas as sources of 1998). new pharmaceutical agents. Mendelsohn & Balick (1995) conclude that only one-eighth of There is a worldwide trend of increasing all drugs that can be potentially developed from demand for many popular, effective species in the rainforests of the world, have been Europe, North America and Asia, growing discovered. Only the Amazon has approximately between 8 and 15% per year (Grünwald & 16% of all the plant species that exist today on BARBOZA, G. E. et al. Medicinal flora of Argentina 11 the Earth, and this wealth increases towards the represents the total number of medicinal plants west of the region (Schultes & Raffauf, 1990; on Earth, and national or regional estimations Sanz-Biset et al., 2009). vary considerably (Schippmann et al., 2002). The use of plants in the practice of medicine Estimates of species used therapeutically are represents one of the biggest human use of the included in the following Table: natural world. There is no reliable figure that

TABLE 1 Number and percentage of medicinal species documented in different countries and regions

Country or region Number of Total number % of Reference medicinal of native medicinal species species flora Bu lgar ia 750 3, 567 21 Schipp ma nn et al. , 20 06 France 900 4,630 19 Schipp mann et al., 2006 Hung ary 270 2, 214 12 Schipp ma nn et al. , 20 06 Jordan 363 2, 100 17 Schipp ma nn et al. , 20 06 Kor ea 1 ,00 0 2, 898 34 Schipp ma nn et al. , 20 06 Malay sia 1 ,20 0 1 5,5 00 7 Schipp ma nn et al. , 20 06 Nepal 900 6, 973 12 Schipp ma nn et al. , 20 06 Pak istan 1 ,50 0 4, 950 30 Schipp ma nn et al. , 20 06 Philipp ines 850 8,931 9 Schipp mann et al., 2006 Sri Lanka 550 3, 314 16 Schipp ma nn et al. , 20 06 Tha iland 1 ,80 0 1 1,6 25 15 Schipp ma nn et al. , 20 06 Vietnam 1 ,80 0 1 0,5 00 17 Schipp ma nn et al. , 20 06 Canarian Islands 619 1,594 39 Pérez de Paz & Hernández Padrón, 1999 Chile 469 4,672 10 Massardo & Rozzi, 1996 China 11,146 27,100 41 He & Gu, 1997; Xiao & Yo ng, 19 98 ; Sh eng ji, 20 02 a Colombia ~5,000 35,000-50,000 10-14 Fonnegra G. & Jiménez R., 2007 In dia 7 ,50 0 1 7,0 00 44 Sh iva, 1996 2,237 30,000 7 Toledo, 1995 United States 2,572 20,000 13 Moerman, 1998 Para guay 1,50 0-3 , 500 6,500-7,000 23-50 Basualdo et al., 1991; Acosta Solís, 1992; Mereles, 2009 Southern encompassing 4,000 22,000 18 Arnold et al., 2000 Namibia, Botswana, Swaziland, South Africa and Lesotho)

TM systems employ relatively few species: herein to the search for unknown therapeutic 500-600 commonly found in Traditional compounds found in organisms. However, this Chinese Medicine (Shengji, 2001); 1,430 in notion may also imply appropriation of legal Mongolian Medicine (Shengji, 2002b); 1,100- entitlements on indigenous, especially 3,600 in Tibetan Medicine (Shengji, 2001, biomedical knowledge of natural resources. The 2002b); 1,250-1,400 in Ayurveda (Dev, 1999); 1992 Convention on Biological Diversity (CBD) 342 in Unani; and 328 in Siddha (Shiva, 1996). establishes sovereign national rights over Bioprospecting as the search for value in biological resources and commits member the biological world is an incredibly ancient countries to conserve them, share the benefits practice. In a general way, any time that a person resulting from their sustainable use, i.e., finding searches for food or other biological value in new drugs, crops, and industrial products, while their enviroment, they are bioprospecting conserving the resources for future research. (McClatchey, 2005). Bioprospecting refers The World Trade Organization (WTO), by 12 Tomo 34 (1-2): 7-365. 2009 KURTZIANA contrast, recognizes ownership of technology molecules (Miller & Brewer, 1992; Grifo et only, rather than knowledge. al., 1997). The economic impact of medicinal Problems associated with biopiracy or plants on the structure of local and national excessive restrictions on research have come to policies is by no means negligible. In the late assume policy prominence in the general 1990s, the annual market value of herbal drugs thematic area of ‘medicinal plant conservation used worldwide was estimated to be around US and use’. The fair and equitable sharing of $45 billion. Today, their value ranges from benefits from bioprospecting is required under US $60 billion to US $100 billion (Shasany et the Convention on Biological Diversity, but it al., 2007). is not always easy to achieve these ideals in Sustainable use of wild populations of practice. While experience is accumulated in medicinal plants requires robust assessment of how this may practically be achieved, it is the distribution and abundance of target species. important, at the present time, that controls While it is increasingly recognized that imposed on scientific research to prevent sustainable harvest of wild populations ‘‘is one biopiracy or theft of local and indigenous of the most misunderstood and misused concepts intellectual property do not unduly restrict in today’s conservation arena’’ (Struhsaker, research that has little or nothing to do with 1998), and that sustainable use has no direct these matters (Hamilton, 2004). connection with the more encompassing concept World trade in medicinal plants accounts of ‘ecological sustainability’ (Hall & Bawa, for about 30 percent of the total drug market. 1993), in practical terms there are often limited This percentage excludes plants used as raw alternative options available to resource material sources for the essential oils required managers, especially given the long history of to manufacture cosmetics, food additives and dependence of rural communities on harvesting for other non-medicinal purposes (Addae- from natural habitats, whether officially Mensah, 2000). Most of these medicinal plants sanctioned or not. Ex situ cultivation and come from less industrialized countries that farming of target resource species is the most supply them as cheap raw materials to the preferable option (Cunningham, 1994; Nantel multinational pharmaceutical manufacturers in et al., 1996; Tran et al., 2001; Pfab & Scholes, the more industrialized countries. Of 76 2004). compounds obtained from higher plants that are The diversity of life on Earth is dramatically present in US prescriptions, only 7 percent are affected by human alterations of ecosystems and commercially produced by total synthesis the reverse is also true: biodiversity in the broad (Farnsworth & Soerjarto, 1991). In 1976, sense affects the properties of ecosystems and, imports of medicinal plants worldwide were therefore, the benefits that humans obtain from estimated to be $US 355 million. This rose to them (Díaz et al., 2006). In general people who $US 551 million by 1980 — an increase of rely most directly on ecosystem services, such over 60 percent within four years (Principe, as subsistence farmers, the rural poor, and 1989). But when these medicinal plants are traditional societies, face the most serious and processed into suitable dosage forms as safe immediate risks from biodiversity loss and this and efficacious drugs, they are sold to the public is a general situation that happen with medicinal at prices far beyond the affordable range for plants (Mertz et al., 2007). the majority of people in the relatively poor The analysis of extensive databases has countries. Yet it is the botanic resources of these become an important tool evaluating the same countries that make possible the knowledge and conservation status of the manufacture of these drugs for commercial biodiversity. A recent assessment (Bramwell, markets (Addae-Mensah, 2000). Of the drugs 2003) estimates that 21% of the world’s flora prescribed in developed countries, 25% derives is threatened. If the latter figure is applied to from about 100 plant species (Comer & Debus, previously earlier extrapolation that 72,000 1996). Natural products also provide the plant species are used medicinally, it leads us scaffold molecules to synthesize further to estimate that about 15,000 medicinal plant BARBOZA, G. E. et al. Medicinal flora of Argentina 13 species are threatened at least to some degree. fast-growing cultivated stocks, whereas wild In Argentina there is no evaluation between populations can be older due to slow growth species global richness and the occurrence of rates and can have higher levels of active threatened species (Villamil, 2006), only data ingredients (Schippmann et al., 2006). from Buenos Aires province exist (Delucchi, Cultivation of medicinal plants is widely 2006). In this province 369 of vascular plants viewed not only as a means for meeting current has been reported as threatened from which 71 and future demands for large-volume production has medicinal uses. of plant-based drugs and herbal remedies, but In different countries, many medicinal also as a means for relieving harvest pressure plants are widely distributed and used across on wild populations (Palevitch 1991; IUCN regions. However, relatively few are cultivated. 1993; Lambert et al. 1997). Thus, the conservation of these plants requires Booming markets with rapidly rising that efforts are directed to key habitats, demands often have devastating effects on wild- including secondary forests, disturbed areas collected species. But for example, if the seven and agrolandscapes (Aguilar-Støen & Moe, forms of rarity described by Rabinowitz (1981) 2007). The majority of companies, the mass- is taken in account it is clear that not all species market, over-the-counter pharmaceutical are affected in the same way by harvesting companies as well as the larger herb pressures: a species which (i) has a narrow companies, prefer cultivated material, geographic distribution, (ii) is habitat-specific, particularly since cultivated material can be and (iii) has small population sizes everywhere, certified ‘biodynamic’ or ‘organic’ (Laird & is more easily over-harvested than species of Pierce, 2002). Nevertheless, the number of any other pattern. Additionally susceptibility or medicinal plant species currently in formal resilience to collection pressure varies among cultivation for commercial production does not species owing to biological characters such as exceed a few hundred worldwide – less than different growth rates (slow-growing vs. fast- 1% of the total number of medicinal plants growing), reproductive systems (vegetative or used. One explanation why are so few species generative propagation; germination rates; cultivated may be found in the observation that dormance; apomixis) and life forms. Species cultivated plants are sometimes considered can be distinguished quite well in their qualitatively inferior when compared with susceptibility to over-collection if their life form wild-gathered specimens (Schippmann et al., and the plant parts collected are viewed together 2006). Scientific studies partly support this. (Table 2). Species most susceptible to over- Medicinal properties in plants are mainly due harvest are habitat-specific, slow-growing and to the presence of secondary metabolites which destructively harvested for their bark, roots or the plants need in their natural environments the whole plant. Patterns of medicinal plant use under particular conditions of stress and by local peoples are considered to vary as a competition and which perhaps would not be function of plant habitat collection, cultural expressed under monoculture conditions. changes, and ecological and biochemical aspects Active-ingredient levels can be much lower in (Albuquerque, 2006).

TABLE 2 Susceptibility of medicinal species to overcollection as a function of life form and plant parts used (adapted from Schippmann et al., 2006).

Wood Bark Root Leaf Flower Fruit/Seed Annual ------High Medium Medium High Biannual ------High Medium Medium High Perennial ------Medium High Low Low Low Shrub Medium Medium? Medium? Low Low Low Tree Medium Medium? Medium? Low Low low

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Many symposiums were organized to In last years many contributions were also coordinate policies for conservation regulation made dealing with macroregions (Roth & management and rigorous scientific research Lindorf, 2002; Gurib-Fakim & Brendler, 2004; to enhance and sustain global medicines from Wiart, 2006; Khare, 2007), countries natural resources (Chaves, 2001; Arnason et (Watanabe et al., 2005; Brouwer et al., 2005; al., 2005; Blacpma, 2006, 2007). For example, González Torres, 2005; Libman et al., 2006; the WHO/IUCN/WWF Guidelines on the Pin & Céspedes, 2009), special sites and Conservation of Medicinal Plants (IUCN, taxonomic groups (Addae-Mensah, 2000; 1993) provided a framework for the Kinghorn, 2002; Tene et al., 2007; Kultur, development of national strategies on the 2007; Teklehaymanot & Giday, 2007; conservation and sustainable use of medicinal Upadhyay et al. 2007; Au et al., 2008; Lulekal plants and put medicinal plant conservation et al., 2008; Sanz-Biset at al., 2009), affections on the international agenda for a diverse set (Kumara et al., 2007; Adams et al., 2007), of stakeholders, including national health health effects of chemical compounds (Okuda, authorities, environmental and trade 2005), ethnic groups (Coe, 2008), specific authorities, conservation groups and policy practices (Ticktina & Paule Dalleb, 2005; makers. The Guidelines constituted an action Mohagheghzadeh et al., 2006) and resources plan for the development of IUCN Medicinal to document, conserve and disseminate Plant Specialist Group, founded in 1994. ancient knowledge (Gaikwad et al., 2008). Nowadays new documents have been prepared Halberstein (2005) reported an extensive (Leaman & Salvador, 2005) referring these bibliography on herbal interventions: 202 guidelines. books ranging from 1847 to 2005 that reflect Many important thematic areas of medicinal the profuse studies made in this field. plants have been covered by recently published A big progress on the study of medicinal handbooks: global perspective of medicinal plants has been made in Latin America in the plants, the evolution of herbal drugs with last years (Calixto, 2005). Nevertheless, civilization, chemical-related information, actual complete catalogs of native medicinal species uses (e.g. cathartic, emetic, carminative, are still missing for many countries. stimulant, antihelmitic, expectorant, etc.), Argentina is the most extensive temperate specific actions (e.g. anti-mitotic activity or country in (Fig. 1). A large part pupil constriction, etc.), molecular biological of its biodiversity can be attributed to the fact activity under the main chemical headings (e.g. that in this territory different biogeographical volatile oils inhibit cancer cells or act on the regions converge (Zuloaga et al. 1999, 2008). central Nervous System), topics such as The wide expanse of its continental area antioxidant therapy or aromatherapy, (2,791,810 km²), as well as its varied technologies in plant research (e.g. production, topographical, climatic and vegetational features, in vitro cultivation, breeding, etc.), latest are essential to the formation of one of the most developments in medicinal applications, hopes, diverse flora in the southern Neotropics. legal issues, conservation, ethnobotany, Argentina is bordered by Uruguay, Brazil and challenges connected with the use of medicinal the Atlantic Ocean to the east, Paraguay and plants (e.g. phytomedicine and biodiversity, to the north, and Chile to the west (Fig. quality control, clinical use and ethnopharmacy, 1). The country is characterized by a wide range etc.) and commercialization (Pengelly, 2004; of macrohabitats across elevation and climatic Packer, 2004; van Wyk & Wink, 2004; Ross, gradients, from 7,000 m to the coastal plains 2005; Yaniv & Bachrach, 2005; Zhang & and from subtropical to polar climates. Among Demain, 2005; Daniel, 2006; Ramawat & these macrohabitats we can find the Merillo, 2008; Ramawat, 2008; Garrido, 2008; phytogeographic regions of Patagonia, Chaco, Dewick, 2009). Altoandina, and Aconquija (Davis et al., 1997).

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Argentina is also one of the 25 most diverse many areas have been deeply studied in relation countries in the world due to their species to their traditional medicine, the following richness and endemism (Caldecott et al., 1996; contributions are worth mentioning: Martínez Zuloaga et al., 2008). In this country, the Crovetto, 1964, 1965, 1968a, b, 1981; Arenas, Northeast and Northwest regions have the 1981, 1983, 2000, 2003; Novara, 1984; Perez highest number of families, genera and species, de Nucci, 1988; Xifreda, 1992; Filipov, 1994, Misiones and Salta being the most important 1997; Lahitte & Hurrell, 1996; Del Vitto et al., provinces (Zuloaga et al., 1999). In a recent 1997, Bocco et al., 1997; Pochettino et al., analysis of the taxonomic diversity of the 1997; Amat & Yajía, 1998, Méndez, 1998; Argentine Dicots, Juárez et al. (2006) found Pochettino & Martínez, 1998; Vignale, 1996, that diversity of this group could not be 1998; Freire, 1998; Gratti, 1998; Lahitte et al., explained by the area of provinces where they 1998; Hilgert, 2001; Núñez & Cantero, 2000; lived, but it varied through latitudinal and Scarpa, 2002, 2004; Martínez, 2002, 2007a, b, longitudinal gradients. They showed that the 2008a, b; Arbo & Tressens, 2002; Kutschker et taxonomic diversity of these plants increases al., 2002; Roig, 2002; Martínez & Planchuelo, from high to low latitudes and west–east 2003; Martínez et al., 2004; Hilgert & Gil, longitudes, and that main diversity centers are 2006, 2007; Barboza et al., 2006; Goleniowsky located in the Northeast region of this country. et al., 2006; Estomba et al., 2006; Menseguez The high diversity of the Northwest provinces et al., 2007; Ladio & Lozada, 2009; Molares & (e.i. Salta, Jujuy, Tucumán) was explained by Ladio, 2009, among others. the latitudinal gradient: this could be due to The first human populations that migrated that tropical eco-regions have their limits of to the Argentine territory twelve or thirteen distribution in this region of Argentina, which thousand years ago were originally nomadic added to the others eco-regions generate a high tribes of hunters and gatherers. By the year 1000 environmental heterogeneity (Juárez et al., A.D., people all over the territory had already 2006). adopted some sort of agricultural and With a rich endemic flora, Argentina has horticultural practices, using the fertile banks 9938 species (Zuloaga et al., 2008), distributed of some rivers after flood waters receded, in 274 families. Hence, the potential for irrigating some valleys in the arid west or developing pharmaceutical bioprospecting burning patches in the forests of the humid schemes is considerably high, particularly in northeast (Giberti, 2008). ethnopharmacology. From an ethnobotanical In the 16th C, the Spanish conquerors of the point of view, the Montenegro’s Materia Médica geographical area comprising Argentina (1702) was the first contribution about the estimated the native population to be around medicinal plants from Paraguay and Misiones half a million. These communities were (Quintana, 1945) but Plantae Diaphoricae characterized by diverse ethnic origin, social (Hieronymus, 1882) was the first scientific organization and cultural practices. Nowadays treatment and significant bibliographical work in Argentina the native population is represented in medicinal plant studies in Argentina; since by 18 ethnic groups (Zamudio, 2005) then, research on folk medicine has provided concentrated in the areas furthest away from valuable information from different regions. the Pampas region, which occupies the centre Detailed compendia of medicinal species native of the country (Table 3). While some ethnic to or naturalized in Argentina include the groups, as the yamanas and sel nam, have almost following: Domínguez, 1928; Sorarú & disappeared, others still make up important Bandoni, 1978; Ratera & Ratera, 1980; components of the population in the northwest Toursarkissian, 1980; Amorín, 1980-1981; (kolla), Chaco (chane, chiriguano, chorote, Amorín & Rossow, 1989-1992; Gupta, 1995; chulupi, mataco-wichi, mocovi, pilaga tapiete, Marzocca, 1997; Rondina et al., 2003; Alonso toba), and Patagonia (tehuelches) (Zamudio, & Desmarchelier, 2006. On a regional scale, 2005). BARBOZA, G. E. et al. Medicinal flora of Argentina 17

TABLE 3 Aboriginal people of Argentina. Source: Zamudio (2005)

Ethnic group Province Population Rankulche Río Negro La Pampa Buenos Aires S/D Huarpes Mendoza San Juan 400 Tapietes Salta 400 Chorote Salta 1,000 Tehuelches Chubut Santa Cruz Tierra Del Fuego 1,000 Tonocotes Santiago del Estero 1,000 Chulupi Salta 1,300 Chane Salta 1,500 Guarani Misiones 3,100 M’bya Misiones 4,800 Pilaga Formosa 5,500 Mocovi Santa Fe Chaco 8,000 Dia guita Calchaquí Catamarca Tucumán Santiago del Estero La Rioja 10,000 Chiriguanos Salta-Jujuy 23,000 Toba Chaco Formosa Salta Santa Fe Buenos Aires 66,000 Wichi Chaco Salta Formosa 85,000 Mapuche Neuquen Río Negro La Pampa Chubut Buenos Aires 100,000 Kolla Jujuy-Salta 200,000 Population in cities Cities: Santa Fe, Resistencia, Posadas, Formosa, Salta 500,000 TOTAL ARGENTINA 1,012.000

In contrast to other regions of America the native groups have lost their identity and have cultures of these ethnic groups were not very become totally absorbed by the national culture. well developed before the arrival of Europeans, This situation is reflected in the use of medicinal with the exception of the kollas, of Incan origin. plants by the people. In rural areas it is still In Latin America, indigenous health systems common to go to the ‘curandero´. However, today range from their traditional and isolated these days their use of medicinal plants is systems, increasingly threatened by deforestation, distorted, as they often prescribe ‘herbs´ as mining, and other activities, to systems strongly cures, but they do so from a ‘westernized´ influenced by traditional western medicine. perspective. The names used often correspond Between such extremes there is a gradient of to traditional hispanic medicine, but the plants intermediate systems. In many Indigenous utilized usually have nothing to do with the communities, TM is still practised, with a link to original ones (Villamil, 2004). allopathic medicine use. In addition to the use of In reference to NW Argentina Hilgert and traditional healers, known as Shamans (more Gil (2007) afirmed that the state of conservation formally Opygua, Pai, and other denominations), of the traditional cultures of this region is variable many families have their own knowledge and and somewhat problematic but to a lesser or a access to medicinal plants for use in emergencies greater extent all the peoples are related to an (Montenegro & Stephens, 2006). The complete hegemonic culture. The Andean medical system, extinction of whole groups of Indigenous peoples, it is formed by a complex combination of herbal such as the Tonocotés, Lule-Vilela, Sanavirones, knowledge, magic elements and propitiatory and Chana-Timbúes in Argentina, has almost rituals. The general cultural picture were certainly resulted in a loss of rich information described as a true tapestry of folk practices on local medicinal plants and their ecosystems where the elements proper of the region and those (Montenegro & Stephens, 2006). that have been introduced by migrations both in In the Pampas, where the main economic pre-Columbian times as well as after the arrival activities of the country are concentrated, the of the Spanish are difficult to sort out. 18 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

Argentine medicinal plants are threatened species uses in Argentina; 3. when the citation of a by overharvesting, habit degradation, taxon reported specific medicinal applications, or unsustainable cultivation practices, and lack of the term ‘medicinal’ for Argentina’s bordering authoritative information. The most serious countries. problem in relation to over-harvesting of the The information was classified into four resource, and the consequent impact on its categories: Taxa, Ethnomedical information/ conservation, appears to be massive collection Distribution, Biological activities, and Chemical data. for commercialization in urban centres (Noher In the Taxa column, details such as Family, Latin de Halac et al., 1985) rather than the effect that name, Vernacular name/s when known, Synonyms, and an Exsiccatum were specified. The nomenclature local use by indigenous groups would have on of the taxa was carefully controlled following different the plant populations. Understanding the databases (Instituto de Botánica Darwinion, 2009), fundamentals of the use and preservation of such W3 Tropicos, Missouri Botanical Garden, St. Louis), a natural resource is thus a determining factor and in some cases, according to the latest revision of in the development of any research framework. the genera. The vernacular names were taken from Among the immediate actions that are the specimen labels, and according to De la Peña necessary to insure the survival of medicinal (1997), Orfila & D’Alfonso (1998), Novara (2003), Barbarán (2008), Peña-Chacarro et al. (2006), and plant species, and the opportunity to use them Martínez (2008), among others. Synonyms are sustainably, Villamil (2004) reported the mentioned only when these names have been found following: (1) preparation of an up-to-date list in the literature indicating medicinal purposes. of species used for medical purposes in the In Ethnomedical information/distribution, countries of the region; (2) survey of the state medicinal uses are described according to the plant of their conservation using the categories of parts, and how the herbal is administered (infusion threat; (3) legislation concerning trade needs to = hot H2O ext., decoction, juice, etc.). In case the be revised and its enforcement strengthened; literature does not indicate the organ used, then Part development of methods of cultivation; (4) not specified is stated. The geographical distribution publicity campaign to instruct the public about and status (native or endemic) of each taxon were this issue and (5)establishment of a national taken from Zuloaga & Morrone (2008), and in some cases modified according to the latest revision of seed or germplasm bank. the genera. The acronomy for each Argentina The objectives of this work are as follows: province is: BAI (Buenos Aires), CAT (Catamarca), 1) to introduce a general review of medicinal CHA (Chaco), CHU (Chubut), COR (Córdoba), plants, 2) to report all scientific data available COS (Corrientes), ERI (Entre Ríos), FOR (Formosa), for us on ethnobotany, chemical composition, JUJ (Jujuy), LPA (La Pampa), LRI (La Rioja), MEN and biological activity of the native medicinal (Mendoza), MIS (Misiones), NEU (Neuquén), RNE flora of Argentina, 3) to identify the plant parts (Río Negro), SAL (Salta), SJU (San Juan), SLU (San Luis), SCR (Santa Cruz), SFE (Santa Fe), SDE used, and its application, 4) to consider the (Santiago del Estero), TDF (Tierra del Fuego e islas taxonomical richness of the native medicinal del Atlántico Sur), TUC (Tucumán). flora, 5) to determine endemism areas of the For chemical data and biological activity tested medicinal flora, and 6) to evaluate the impact in vitro and in vivo, we conducted an electronic of the native medicinal flora in bioprospecting. literature search of NAPRALERT (Natural Product Alert, University of Illinois, Chicago), MEDLINE, Methodology IBIDS (The International Bibliographic Information on Dietary Supplements), Science Direct, Pub Med, The Argentine medicinal flora is presented as a Bioline International Office Site, CNRS (Centre checklist where families, species, and infraspecific National de la Recherche Scientifique), Wiley taxa are alphabetically arranged. The checklist only InterScience, BioInfoBank Library, InformaWorld, includes native species; naturalized or adventitious and CAB Abstracts databases updated to March plants were excluded. The selection of the taxa from 2009, in addition to performing hand searches in the literature was made following three criteria: 1. other specific literature (Glasby, 1991; Harborne when the citation of a taxon specified therapeutic & Baxter, 1997; Hegnauer, 1973, 1986, 1989, uses in Argentina; 2. when the citation of a taxon 1990; Hegnauer & Hegnauer, 1994, Eich, 2008) included the term ‘medicinal’ in describing the among others. The keywords used for the electronic

22 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

Average number of endemic taxa (average pampasica, Senecio uspallatensis, Trichocline of provinces) is 28 (24 % with respect the total plicata, Trichocline sinuata, lilloana, 116 endemics of Argentina) showing its Berberis grevilleana, inflexa, Polygala importance at the scale of the country. The areas stenophylla, and Valeriana ferax). Some species where the endemic species are mostly found are very rare with a restricted distribution follow a characteristic pattern: the largest (Cyperus spectabilis var. jujuyensis, amount of medicinal endemic species is located Chiliophyllum densifolium, Mutisia saltensis, in the provinces of: Catamarca (48.69 % with Senecio pogonias, S. uspallatensis, Trichocline respect total 115 medicinal endemics of plicata, Senna kurtzii, Gentianella imberbis, G. Argentina), La Rioja (47.82 %), Mendoza parviflora, Sphaeralcea philippiana, (46.95%), San Luis (46.95%), Córdoba (45.21 Siphoneugena occidentalis) while others need %), and San Juan (43.47 %). When the priorities in conservation practices due to the relationships are referred with respect the total progressive destruction of their habitats (e.g. medicinal flora per province, Mendoza Polylepis australis, Condalia microphylla, (14.28%), San Luis (13. 70%), and La Rioja Lippia spp.). (12.67%) are the main important. It appears that ecoregions of Monte and Chaco have the Discussion highest number of endemisms of medicinal plants. There is an estimated number of medicinal According to the data shown, the provinces plants of 40,000-70,000 species in the world with greater diversity of medicinal flora match and still there is a lot of traditional knowledge the type of species diversity and infraspecific that has not yet been really explored (Verpoorte, taxa of the vascular flora reported by Zuloaga 2007). In Argentina, the composition of the et al. (1999, 2008) and the pattern of Dicots native ethnopharmacopoeia has increased diversity observed by Juárez et al. (2006): the considerably specially with the contribution of Northeast and Northwest regions have the detailed ethnobotany studies carried out in highest number of families, genera and species different aborigenous and rural communities of medicinal plants. In the northwestern region, where their healthcare systems continue to rely the richest area in medicinal species grows 28- on their traditional plant-based medicines 37 % of the endemics (Salta, Jujuy, and (Martínez Crovetto, 1964, 1965, 1968a, b, 1981; Tucumán, cfr. Table 6). Misiones, in turn, is Arenas, 1981, 1983, 2000, 2003; Xifreda, 1992; the province with the highest rate of biodiversity Filipov, 1994, 1997; Del Vitto et al., 1997, (Zuloaga et al. 1999, 2008), but only with 2.60 Bocco et al., 1997; Pochettino et al., 1997; Amat % of medicinal endemic species. & Yajía, 1998, Méndez, 1998; Pochettino & It is interesting to point out that the Martínez, 1998; Vignale, 1996, 1998; Gratti, medicinal endemics are not used profusely. 1998; Lahitte et al., 1998; Hilgert, 2001; Núñez Even more, 13 of these species are cited in the & Cantero, 2000; Scarpa, 2002, 2004; Martínez, literature just as ‘medicinal’ without indicating 2002, 2007a, b, 2008a, b; Kutschker et al., a particular use or the organ used (e.g. Schinus 2002; Roig, 2002; Martínez & Planchuelo, johnstonii, Asclepias flava, Gochnatia 2003; Martínez et al., 2004; Hilgert & Gil, glutinosa, Microliabum candidum, Cnidoscolus 2006, 2007; Goleniowsky et al., 2006; Estomba loasoides, etc.). The potential of these plants et al., 2006; Menseguez et al., 2007; Ladio & has not been evaluated in detail especially in Lozada, 2009; Molares & Ladio, 2009; its chemical compounds (No data: 68 species) Eyssartier et al., 2009). The 1,529 medicinal and bioactivity (No biological test: 86 species). species registered in this review, which represent near the 15 % of the total Argentinean flora, In terms of conservation, 13 endemic species demonstrate that we have a good source of can be considered endangered since the only promising plants that should be studied in detail. organ used in the majority of them is the root This value will be still greater if we also (Eryngium agavifolium, Hypochaeris consider the introduced medicinal species. BARBOZA, G. E. et al. Medicinal flora of Argentina 23

Many of the industrially and commercially On the other hand, many of these communities used pharmaceuticals derive from secondary have no supply of clean drinking water, their metabolism produced by microbes, plants and wells being situated close to latrines, or shared animals. About 35,000 (some estimates increase with farm animals, thus increasing the risk of the number to 70,000), out of 350,000 plant ingesting pathogens. species known so far, serve medicinal purposes The intensive harvesting of wild plants or worldwide, and less than 0. 5 % have been their reproductive organs which evidence chemically investigated (Shasany et al., 2007). neglects in conservation practices or habitats, The search for potentially active compounds poses an increasing threat to the country’s has been the objective of several research medicinal plants (Núñez & Cantero, 2000; groups and much progress has been done in the Martínez et al., 2006). Medicinal plants are Argentinean medicinal flora in the last years. directly used from the wild. Their use is usually Despite of this, ca. a 46 % and a 58 % of the not fatal to individual plants, however in many species remain unexplored in their chemical cases like Hedeoma multiflorum, Minthostachys composition and biological activity, verticillata, Julocroton argenteus, Baccharis respectively, as it is shown in this paper. crispa, Trixis divaricata subsp. discolor, This review showed that nearly 300 uses Passiflora caerulea, and Equisetum giganteum have been mentioned in literature although many (Martínez et al., 2006), in Córdoba province, of them are more or less similar. With the heavy or continued exploitation risks the purpose to retain information as much as regeneration of the natural sourced population. possible we only mention, from the Appendix Perhaps the principal threat to medicinal species I, 75 of them. General weakness, rheumatic is nor over-harvesting but the destruction and pains, contusions and myalgia, kidney disorders, conversion of their habitats to other purposes. heart disorders, gastrointestinal upsets, Many types of action can be taken in favour neuralgias, coughs and colds, sexual disorders, of the conservation and sustainable use of are the most commonly reported indications to medicinal plants. Some of these are undertaken be treated with medicinal plants. directly at the places where the plants are found, In Argentina, regional works had cited the while others are less direct, such as some of gastro-intestinal illness as the most frequent those relating to commercial systems, ex situ problem whilst ailments connected with the conservation and bioprospecting. In the latter nervous systems was the least frequent reported cases, actions taken will not lead to in situ (Molares & Ladio, 2009). In this review, the conservation unless they feed back to pattern found was not so lineal. This highest improvements in the field. Probably the single frequency for the gastro-intestinal category has most important role for medicinal plants in also been registered in numerous studies carried biological conservation is their ‘use’ to achieve out in different human groups throughout the conservation of natural habitats more generally. world (e.g., Milliken & Albert, 1997; Ankli et This stems from the special meanings that al., 1999; Schlage et al., 2000; Hilgert, 2001, medicinal plants have to people, related to the Begossi et al., 2002, Scarpa, 2002). The high major contributions that they make to many citing frequency of gastro-intestinal uses could people’s lives in terms of health support, be due to the kind of food ingested, foods not financial income, cultural identity and livelihood well preserved hygiene and also the easy security (Hamilton, 2004). diagnosis of these illness and effectiveness of Land use has increased the rate of species different species to deal with them. During the extinction not only by replacing natural last century, the traditional diet has undergone ecosystems, but also by changing the changes, resulting in an increase in the disturbance regime. In Argentina land cover consumption of refined flour and meat, and a changes associated with agriculture, grazing by decrease in the consumption of wild and domestic herbivores and deforestation have had cultivated vegetables, leading to an unbalanced an enormous impact on the structure and diet, lowing fibre content (Ferrari et al., 2004). functioning of many ecosystems where 24 Tomo 34 (1-2): 7-365. 2009 KURTZIANA medicinal plants are one of the main vegetation constituents is now available (Emerenciano et components, for example natural grasslands and al., 2007). Among the great variety of chemical native forest in intermountain valleys of classes isolated from these plants, terpenoids, Córdoba province (Cantero, pers. comm.). Other , , polyacetylens, dramatic changes can be found for Tercero benzofurans, alkaloids, sesquiterpene lactones, Arriba county, located in the same province essential oils, triterpenes, diterpenes, cyanogenic (33°12’S, 64°W), in the Northern Espinal , and other minor constituents, can phytogeographic unit (Paruelo et al., 2001) be cited (Hegnauer, 1977, 1989; Emerenciano, where native woodlands were converted to 2007). In our country, comprises introduce summer crops. ca. 1,490 species (indigenous and introduced) In order to set criteria to establish the (Zuloaga et al., 1999), and 272 native taxa (ca. conservation priorities of a species, based on 18 %) have been reported with medicinal uses its economic and social importance, and (this review). The Baccharis is one of potential genetic erosion, a national program the most important considering its enormous on medicinal germplasm conservation needs to relevance regarding its medicinal, commercial, be created. This national program should and biological applications (Bastos, 2008). include: (1) ethnobotanical studies; (2) Thirty six species (37.5 % ) of the 96 growing germplasm collection and characterization; and in Argentine (Giulano, 2000) have medicinal (3) ex situ and in situ conservation. Some properties, and the majority of them has been criteria to define species priority conservation studied phytochemically (ca. 70 %) or has at could be described as follows: (a) species with least one biological activity tested (52 %). Only proven medicinal value, including those four species (B. genistifolia, B. pingraea fo. containing known active substance(s) or angustissima, B. sculpta and B. vulneraria) lack precursor(s) used in the chemical– of chemical data and biological test. Senecio pharmaceutical industry, or at least those and Eupatorium are also genera with high demonstrating pre-clinical and toxicological number of medicinal taxa (23 and 20 results; (b) species with ethnopharmacological respectively), and coincidently with Baccharis, information widely used in TM, and which are chemical and pharmacological information threatened or vulnerable to extinction; (c) together is missing for a few members (cfr. species with chemotaxonomic affinity which Appendix I). produce specific natural products. The second representative medicinal family is . The tremendous morphological Best representative families diversity of this family due to the large number of species in the world (over 18,000), is also The three best representative families with evidenced in the production of a large number medicinal taxa in Argentina are Asteraceae, of metabolites with considerable structural Fabaceae, and Solanaceae. Members of these diversity (Waterman, 1994). The major groups families have been used by man for the of secondary metabolites are N-containing prevention and relief of medical disorders since metabolites (true alkaloids, pseudoalkaloids, the dawn of civilization. Today, they continue cyanogenic glycosides, non-protein amino acids, to figure prominently in TM, especially in lectins), flavonoids, , furocoumarins, developing countries. , terpenes, etc. (Waterman 1994; The economical and medicinal importance Hegnauer & Hegnauer, 1994). The main of the Asteraceae, one of the largest plant importance of the Fabaceae is economical families in the world (ca. 23,000 species; cfr. because of the seeds which are rich in high Bremer, 1994), has been widely described quality protein, providing man and animals with (Heywood et al., 1977; Wagner, 1977; a highly nutritional food resource, besides of Emerenciano et al., 2007). Chemically, this the value for its timber, dyes, resins, gums, family has been extremely studied and an insecticides, fibers, forage, fodder, ground enormous amount of information on its organic cover, green manures, etc. (Allen & Allen, BARBOZA, G. E. et al. Medicinal flora of Argentina 25

1981). In terms of medicinal interest, more than Among the remaining families that 30 species had already been reported by contribute with more than 1 % of medicinal Hieronymus (1882) in our territory, and taxa, Verbenaceae, Lamiaceae, Myrtaceae and nowadays 113 native medicinal taxa are Apiaceae are of central importance because of registered (this review). Among them, ca. 42 % its aromatic members. The essential oils lacks of chemical information and ca. 65 % of composition of several members of these pharmacological activity. However, much families, with the exception of Apiaceae, have progress has been done in these aspects in some been reported to be effective as virucidal, species, such as Bauhinia forficata var. pruinosa antibacterial, , trypanocidal, or Erythrina crista-galli, or the Acacia species. acaricidal, nematicidal, fumigant and repellent In relation to Solanaceae (ca. 2,500 spp.), against head lice, or to have analgesic, members of this family are valued in traditional antioxidant, anti-diarrheic, spasmolytic, and herbal medicine for treatment of a wide hepatotoxic, choleretic, antispasmodic, anti- range of ailments on a global scale. Its inflammatory, cytoprotective, anti-allergic, and contribution to medicine and drug therapy lymphoproliferative activity (cfr. Appendix I). makes it one of the top-ranking families of Medicinal and aromatic plants are a diverse drug-yielding plants (Roddick, 1991). group of plants with potential to contribute to Solanaceae provides a) drugs used in economic development (Juliani et al., 2007). conventional chemotherapy, b) plants used in Zygadlo & Juliani (2003) and Juliani et al. traditional/herbal medicine, and 3) plants used (2007) reported the increasing commercial as a source of precursors of pharmaceutical demand of herbal, medicinal and aromatic plants (Roddick, 1991). As occurs in in Mid-Western Argentina. Many species Asteraceae and Fabaceae, this family is also included in Appendix I integrate the lists of diversified in the production of secondary species given by these authors. chemical compounds, being the main ones: alkaloids (simple pyrrolidines, N- Conclusions acylpyrrolidines, pyrrolidine-type nicotinoids, tropanes, calystegines, pyrrolizidines), - The recognized native medicinal flora of –derived alkaloids, - Argentina consists of 1,529 taxa. One derived metabolites (phenylethylamine, hundred and fifteen taxa are endemics. acids, phenylethanoid - Knowledge about the chemical composition alcohols, phenylmethanoids, capsaicinoids, and the biological activity of the medicinal hydroxycoumarins), hydroxycinnamate flora needs to be further developed. More conjugates (hydroxycinnamoyl glucose esters than 45 % of the species has not yet been and O-glucosides, , N- chemically analyzed, while 58 % has not been Acylramines), flavonoids, , terpenoids tested pharmacologically on any subject (monoterpenoids, sesquiterpenoids, considering the information available for us. diterpenoids, triterpenoids, , steroidal sapogenins/, steroidal - Asteraceae is the richest family among alkaloids), and fatty acids and their derivatives medicinal taxa (272) and medicinal (Eich, 2008). The medicinal members of endemics (36). Solanaceae in Argentina comprise 52 taxa, and - The northwestern and northeastern regions with the exception of the Solanum species, two show the greatest diversity in terms of native species of Fabiana, and Grabowskia obtusa, medicinal flora. the remaining ones have at least chemical or pharmacological information. The most - The provinces of Salta and Jujuy have the promising species is Fabiana imbricata «palo highest number of medicinal taxa in pichi», in which many pharmacological studies Argentina (795 and 756 taxa, respectively). have been focused (Alonso & Desmarchelier, - The Monte ecoregion is the richest area in 2006 and bibliography herein) medicinal endemics. With respect the total 26 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

medicinal endemic of the country, viability, as many other endangered species, Catamarca has the highest percentage of as Gentianella parviflora, do not qualify for endemic species (48.69 %) in its medicinal cultivation they will enter cultivation only flora; at the same time Mendoza has the with the help of public domestication highest number of endemics (14.55%) programmes. For all other harvested respecting the medicinal flora per province. medicinal species the priority conservation Formosa is one of the poorest areas in option is sustainable harvest from wild endemics medicinal plants (1.73%). Tierra populations. del Fuego has not any endemic. - Due to the richness and distribution of - Chemical constituents and biological activity medicinal flora in Argentina, the importance are aspects scarcely explored in the of preserving the prevailing natural and medicinal flora of Argentina, probably due seminatural ecosystems of our territory needs to a combination of lack of appropriate to be directly addressed. Overharvesting, land policies and laws to support the use of conversion (deforestation and clearing for medicinal plants to fulfill healthcare needs, agriculture, and urban development) poses a and low interest in their research among the serious threat to many medicinal plants, scientific community. Therefore, due to its especially given the small population density rich flora and empirical background which of some species or their restricted distribution. should not be ignored, pharmaceutical For these reasons, approaches to wild species bioprospection is a promising ground. collection that engage local, regional, and national collection enterprises and markets - Relatively few native medicinal plants in the work of conservation and sustainable species are cultivated. The great majority is use of medicinal species are urgently needed. still provided by collection from the wild. The ecoregions that deserve special attention This trend is likely to continue over the long due to the number of species collected are term due to numerous factors: most the following: Puna, Yungas Chaco, and Altos medicinal plants are traded locally and Andes, finally the Monte ecoregion deserves regionally rather than internationally, the especial attention mainly due to its costs of domestication and cultivation are endemisms. A national program on medicinal still high, and land in mainly used for germplasm conservation needs to be created. cultivation of food crops. Wild collection practices are the unique secure valuable income for many rural households. Acknowledgements - For threatened and profitable medicinal plant The authors are especially grateful to species, like Minthostachys verticillata, colleagues who provided information or Hedeoma multiflorum, Achyrocline literature to complete the checklist. We would satureoides, Passiflora caerulea, also like to thank the assistance of the technical Acantholippia seriphioides, Lippia staff of the Museo Botánico de Córdoba (UNC) turbinata, Baccharis crispa, cultivation is a and Facultad de Agronomía y Veterinaria conservation option because the constant (UNRC), and fruitful comments of the two drain of material from their populations is anonymous reviewers on our manuscript. This much higher than the annual sustained yield. work was supported by Secyt-UNC, Secyt- If the demand for these species can be met UNRC, Ministerio de Ciencia y Tecnología from cultivated sources the pressure on the (Córdoba, Argentina), and CONICET. wild populations will be relieved. In these cases, the need for strict conservation of Literature cited remaining populations, improved security of germplasm ex situ and investment in Acosta Solís M. 1992. Vademecum de las plantas selection and improvement programmes is medicinales del Ecuador. Ediciones Abya-Yala, extremely urgent. With respect to economic Quito. BARBOZA, G. E. et al. Medicinal flora of Argentina 27

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TAXA ETHNOMEDICAL BIOLOGICAL CHEMICAL DATA (Family, Latin Name, INFORMATION/ ACTIVITIES Vernacular Names, DISTRIBUTION Synonyms, Exiccatum) ASPLENIACEAE Asplenium monanthes Leaf, infusion: to stimulate No biological Frond. Tannins L. parturition test Calaguala : diaphoretic Morero 84 (CORD) Part not specified: diaphoretic BAI, CAT, C OR, JUJ, LR I, MIS, SAL, SLU, TUC AZOLLACEAE Azolla cristata Kaulf. Entire plant: decoction and infusion No biological Fresh entire plant. Propanoic acid, 3-amino-3-phenyl γ-l- Helechito de agua, as a tonic; asthenia; body-stimulating, test glutamyl: proteids alfombra antirheumatic, aphrodisiac Dried leaf. Adonixanthin, rhodoxanthin, zeaxan: carotenoids Azolla caroliniana Willd. (sub nom. A. caroliniana) (sub nom. A. caroliniana) Hunziker 10348 (CORD) CHA, COR, COS Azolla filiculoides Lam. Entire plant: asthenia; body- Entire plant: Entire plant. Ethanolamine, serine, lipids; choline, alkaloid- Helechito de agua, peste stimulating, antirheumatic, antitumor and misc; aliphatic alcohol, aliphatic ketone, aliphatic ester: del agua, alfombra aphrodisiac cytotoxic alkanols; cholesterol, campesterol, β-sitosterol: steroids Ariza Espinar 2538 BAI, CAT, C HA, COR, CO S, FO R, activity Dried leaf. Rhodoxanthin, lutein epoxide, adonixanthin, (CORD) JUJ, LPA, L RI, MEN, R NE, SAL, zeaxanthin: carotenoids SCR, SFE, SJU BLECHNACEAE Blechnum cordatum Plant: eyes disease No biological Dried entire plant. Chlorogenic acid: phenylpropanoid; (Desv.) Hieron. Rhizome: abortive, emmenagogue test : flavonol Palmita, costilla de vaca Frond: eyes disease Blechnum chilense (sub nom. B. chilense) (Kaulf.) Mett. BAI, CHU, COR, MEN, NEU, RNE, Subils 1761 (CORD) SAL, SCR, SLU, TDF

35 1 For References, see Appendix II

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Blechnum hastatum Plant: abortive, emmenagogue, No biological No data Tomo34(1-2):7-365.2009 Kaulf. contraceptive, emetic test Palmilla, quilquil, iquide CHU, COR, MEN, NEU, RNE, SCR de la pampa, arriquilquil, arri cül cül Cantero s.n. (RIOC 3595) Blechnum magellanicum Plant: eye disease No biological No data (Desv.) Mett. CHU, NEU, RNE, SCR, TDF test Kättälapi Ulibarri 1023 (SI) Blechnum occidentale Plant: lungs and urinary disorders Entire plant: Dried leaf. Rhodoxanthin, lutein epoxide, lutein, L. Part not specified: infusion and hypothermic, adonixanthin, zeaxanthin, violaxanthin, antheroxanthin: Doradilla decoction to dissolve renal calculi, diuretic, and carotenoids Hunziker 893 (CORD) and for treatment of nervous hysteria antibacterial JUJ, MIS, SAL, TUC activity Blechnum pennamarina Aerial plant: medicinal No biological No data (Poir.) Kuhn BAI, CHU, COR, JUJ, NEU, RNE, test Punque SAL, SCR, SLU, TDF, TUC Morero 26 (CORD) DAVALLIACEAE Nephrolepis cordifolia Leaf, infusion: emmenagogue Part not Fresh leaf. Leucoanthocyanins, lutein epoxide, lutein, β- (L.) C. Presl Root: febrifuge; decoction: for cough specified: DNA ryptoxanthin, rhodoxanthin: carotenoids Helecho serrucho Apical cutting, infusion: polymerase and Ariza Espinar 2865 anthelmintic RNA (CORD) Rhizome and leaf: anthelmintic transcriptase BAI, C AT, COR, COS, JUJ, SAL, inhibition SFE, TUC

DENNSTAEDTIACEAE KURTZIANA Hypolepis repens (L.) Leaf: menstrual diseases Frond: No data Presl CAT, COR, JUJ, MIS, SAL, TUC antibacterial Ala de cuervo, ala e cuervo activity Aquino 145 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Pteridium Rhizome, decoction: antitussive No biological Aerial parts. Phenolic and condensed tannins arachnoideum (Kaulf.) (tuberculosis), diaphoretic test Maxon Rhizome + frond: antitussive, Helecho macho astringent, diuretic Pteridium aquilinum var. Leaf, infusion: antirheumatic, arachnoideum (Kaulf.) antitussive. Brade BAI, CAT, CHA, COR, COS, ERI, Kurtz 10540 (CORD) JUJ, LRI, MIS, SAL, TUC DICKSONIACEAE Lophosoria Part not specified: to treat wounds No biological Dried frond. Fern-9(11)-ene, hopane, dryocrassol, quadripinnata (J.F. and test adipedatol, diplopterol: triterpenes; ginnone: alkanone C5 or Gmel.) C. Chr. hemmorhagia more; : flavonol Burkart 6358 (SI) NEU, RNE DRYOPTERIDACEAE Cystopteris fragilis (L.) Leaf, infusion: expectorant and in No biological Dried aerial parts. Glucose-3-sulfate,1-caffeyl, shikimic Berhn. case of delayed menstruation; test acid: ; mangiferin: xanthone; 1-6- Culandrillo, culantrillo, diaphoretic, antitussive dihydroxy-3-5-7-trimethoxy, vincenin 2: cabello de ángel, cabello Rhizome, infusion: anthelmintic Fresh leaf. Leucoanthocyanins, lutein epoxide, lutein, β- de venus CAT, CHU, COR, JUJ, NEU, RNE, ryptoxanthin, rhodoxanthin: carotenoids; astragalin, Cantero s.n. (RIOC SAL, SCR, SLU, TDF, TUC -3-O-β-D-(3''-sulfate)-glucoside, kaempferol-3- 2142) O-β-D-(6''-sulfate)-glucoside: Polystichum montevi- Plant: anthelmintic No biological Essential oil. α-pinene, α-terpineol, pulegone, α-muurolene dense (Spreng.) Rosenst. BAI, COR, JUJ, LRI, MIS, SAL, test var. montevidense SLU, TUC Ala de cuervo, helecho macho Morero 8 (CORD) Polystichum montevi- Plant: anthelmintic; to help No biological No data dense var. squamulosum parturition test (Hieron.) Hieron. COR, JUJ, SAL, TUC Ala de cuervo, helecho macho Morero 13 (CORD)

37

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Rumohra adiantiformis Rhizome: astringent, emmenagogue, Leaf: No data Tomo34(1-2):7-365.2009 (G. Forst.) Ching diaphoretic, aids digestion antibacterial Calaguala BAI, CHU, COS, MIS, NEU, RNE, activity Fortunato 5799 (BAB) SCR, TDF EQUISETACEAE Equisetum bogotense Entire plant, infusion: for ulcers and Dried entire Dried aerial parts. Astragalin, -7-O- β-D- Kunth wounds, diuretic; decoction: urinary plant: β- glucoside, kaempferol-3-O-(6''-O-malonyl-glucoside, Limpiaplata, pinko-pinko, antiseptic, diuretic, astringent, glucuronidase kaempferol-3-O-(6''-O-malonyl-glucoside)-7-O-glucoside, yerba del platero, menstrual diseases, used in inhibition, kaempferol-3-O-β-d-glucoside-7-O-rhamnoside, tembladera pregnancy and facilitate birth, post anticrustacean kaempferol-3-O- β-d-sophoroside, -3-O-(6''-O- cola de caballo, Hierba de partum pains and disease activity malonyl-glucoside): flavonols; 5-caffeoyl -shikimic acid, 5- la plata, cepa de cahuel Aerial parts: antidiarrheal, astringent, Stem, O-caffeoyl -shikimic acid, dicaffeoyl-meso-tartaric acid: Zavala s.n. (RCV) diuretic, stomachic, liver stimulant; anti- antitumor, phenylpropanoids haemorrhagic; urinary disinfectant cytotoxic and CHU, COR, COS, JUJ, MEN, NEU, diuretic activity RNE, SAL, SJU, SLU, TUC Equisetum giganteum L. Dried aerial parts, infusion: hepatic, Dried entire Dried entire plant. Palustrin: alkaloids; quercetin, Colai caballo, yerba del diuretic and for scrofula, dermatitis and plant: kaempferol-7-diglucoside: flavonoids; tannins; minerals, platero inflammations; for gonorrhea; astringent, neuritogenic, vitamins, saponins, flavonoids, such as flavone, , cola de cabello, cabello, against kidney and bladder calculi and for diuretic, flavonol and flavanol cola de caballo, chigote de cutaneous affections; antidiarrheal, antiviral, fraile, yerba de caballo, vulnerary, emmenagogue, and to treat antimicrobial, cola ‘e caballo internal hemorrhage, dysentery, for and smooth Cocucci et al. 254 revitalization of fingernails and lifeless muscle relaxant (CORD) hair, menstrual diseases, used in activity pregnancy and facilitate birth, for pain in the waste and back ache; decoction: to treat varicose veins, for circulatory and cardiovascular diseases

BAI, CAT, CHA, COR, COS, DFE, KURTZIANA ERI, FOR, JUJ, LPA, LRI, MEN, NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina LOMARIOPSIDACEAE Elaphoglossum gayanum Leaf: emmenagogue, against hepatic No biological No data (Fée) T. Moore affections; blood depurative test Calaguala BAI, COR, JUJ, SAL, SLU, TUC Barboza et al. 1143 (CORD) LYCOPODIACEAE Huperzia fueguiana Plant: vomiting, purgative, No biological No data (Roiv.) Holub anthelmintic, emmenagogue test Vervoorst 4628 (LIL) SCR, TDF Huperzia saururus Plant: aphrodisiac, tonic, against Aerial plant: Aerial plant: Lycopodine, clavolonine, sauroine, 6-OH (Lam.) Trevis alopecia, action on memory and inhibitory lycopodine; HS1; HS2: Lycopodane group alkaloids; Cola de quirquincho, learning; appetitive; hypoglycaemic, activity on sauroxine, lycodine, N-methyllycodine, N-acetyllycodine, pyiyai, pillijai emmenagogue, abortive, purgative, acetylcholineste- huperzine A, HS3, HS4: Flabellidane group alkaloids Barboza 129 (CORD) for asthenia; tonic, stimulant rase (alkaloid BAI, CAT, COR, JUJ, SAL, SLU, extract) TUC Lycopodiella cernua (L.) Plant: anti-haemorrhagic, diuretic, Leaf: Aerial plant. Cernuine, lycocernuine: alkaloids; cermizines Pic. Serm. antidiarrheal, astringent, anti- antibacterial and A and B: phlegmarane-type alkaloids; cermizine C, Lycopodium cernuum L. inflammatory, antirheumatic antifungal senepodines G and H: quinolizidine alkaloids; quinolizidine Arbo 8718 (CTES) COS, ERI, MIS activity and a piperidine ring, cermizine D: C16N2 type alkaloid; cernuine N-oxide, lycocernuine N-oxide: cernuane-type alkaloids (sub nom. L. cernuum) Lycopodium clavatum Dried entire plant, infusion: Dried aerial Dried entire plant. Cholest-5-en-3-β-ol-24-α-ethyl, 22- L. emmenagogue, anti-catarrhal, parts: dehydro-campesterol, cholesterol, cholesta-5-22-dien-3-β- Musgo de cabezuela, carminative, laxative, aphrodisiac antipyretic ol-24-α-ethyl, cholest-5-en-3-β-ol-24-α-ethyl: steroids; yerba de bruja, yerba de Frond: to treat rheumatism, epilepsy activity clavatine, clavatoxine, clavolonine, fawcettiine, lycopodine: gitanos, gateadera, and renal disfunction Spores: quinolizidine alkaloids; lycoclavanin, lycoclavanol, α- colchón de pobre, Pollen, tincture: tonic, used in estrogenic and onocerein: triterpenes. Licopodio, pilliján, azufre tuberculosis, and in bladder catarrh androgenic Spore. Hydrocaffeic acid: phenylpropanoids vegetal Dried shoots, infusion: for diabetes effect, uterine Morero 89 (CORD) Dried stem, infusion: decongestant, stimulant effect and used in hepatitis COR, JUJ, MIS, SAL 39

40

POLYPODIACEAE Tomo34(1-2):7-365.2009 Campyloneurum aglao- Part not specified: medicinal No biological No data lepis (Alston) de la Sota CAT, JUJ, SAL, TUC test Pori-pori, canchalagua Zuloaga 7604 (SI) Microgramma Plant: astringent, diaphoretic, No biological No data mortoniana de la Sota antirheumatic, antiseptic test Arbo 6131 (CTES) BAI, COS, MIS, SAL Microgramma Plant: against vaginal mycosis, anuria, Dried rhizome: Root + stem. Flavonoids and tannins squamulosa (Kaulf.) de urine with blood, wounds, aphrodisiac, antiulcer la Sota for infections, hernia and prolapse, used activity Pori-pori, canchalagua, poli- in pregnancy and facilitate birth por, polipodio escamoso, Dried rhizome: to treat stomach calaguala del mate ulcers Lorentz 90 (CORD) CAT, CHA, COS, JUJ, MIS, SAL, TUC Microgramma Entire plant: antitussive, anti- No biological No data vacciniifolia (Lang. & asthmatic, astringent, dysentery, test Fisch.) Copel against diverse types of swelling, Giorgis et al. 1044 antidiarrheal, for intestinal disorders (CORD) BAI, CHA, COR, COS, FOR, MIS, SFE Phlebodium areolatum Rhizome: anti-hypertensive, No biological No data (Willd.) J. Sm. emmenagogue, for arthritis, diarrhea, test Calaguala, calahuala, stomach-ache, skin disorders, kidney helecho problems azul (sub nom. Polypodium aureum L.) Morero 108 (CORD) Rhizome + leaf: analgesic, expectorant, febrifuge, tranquilizer, depurative,

diuretic, anti-inflammatory, KURTZIANA emmenagogue, and spasmolitic properties (sub nom. Phlebodium pseudoaureum (Cav.) Lellinger COR, JUJ, MIS, SAL, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Pleopeltis macrocarpa Entire plant: abortive No biological No data (Bory ex Willd.) Kaulf. BAI, CAT, JUJ, MIS, SAL, TUC test Zuloaga 2948 (SI) Pleopeltis pinnatifida Entire plant: abortive No biological No data Gillies ex Hook. & Grev. (sub nom. P. argentinum) test Polypodium argentinum BAI, CAT, COR, JUJ, LPA, LRI, Masón MEN, SAL, SDE, SJU, SLU, TUC Morero 25 (CORD) Pleopeltis squalida (Vell.) Leaf, infusion.: contraceptive; No biological No data de la Sota digestive, anthelmintic test Polypodium squalidum (sub nom. P. squalidum) Vell. BAI, CAT, CHA, COS, ERI, FOR, Deginani 1674 (SI) JUJ, LRI, MIS, SAL, SFE, TUC Pleopeltis tweediana Aerial parts: emmenagogue, No biological No data (Hook.) A.R. Sm. resolutive, pectoral test Calaguala, calahuala, chuc- CAT, JUJ, LRI, SAL, TUC cho, chyjcho, polipodio, kalahuala Polypodium tweedianum Hook. Guaglianone 2003 (SI) Serpocaulon gilliesii (C. Plant: abortive No biological No data Chr.) A.R. Sm. (sub nom. P. lasiopus) test Polypodium lasiopus BAI, CAT, COR, JUJ, SAL, SLU, Klotzsch TUC Morero 28 (CORD) PTERIDACEAE Adiantopsis Plant: astringent, expectorant; No biological No data chlorophylla (Sw.) Fée against menstrual disorders test Culantrillo, ala e cuervo BAI, CHA, COR, COS, ERI, JUJ, Morero 34 (CORD) MIS, SAL, SFE, TUC

41

42

Adiantum chilense Kaulf. Leaf: emmenagogue, expectorant, No biological No data Tomo34(1-2):7-365.2009 Culantrillo, culandrilla, diuretic test doradilla BAI, CAT, CHU, LPA, LRI, MEN, Hosseus 48 (CORD) NEU, RNE, SCR, SJU, SLU, TDF Adiantum lorentzii Plant: abortive, menstrual diseases, No biological No data Hieron. used in pregnancy and facilitate birth, test Culantrillo, culandrillo post partum pains and diseases Martínez 164 (CORD) Leaf: antitussive CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SLU, TUC Adiantum orbignyanum Plant: abortive No biological No data Mett. ex Kuhn Leaf: emmenagogue, expectorant test Culantrillo CAT, COR, JUJ, SAL, TUC Cantero et al. s.n. (RIOC 2119) Adiantum Part not specified: cephalalgic, for No biological No data pseudotinctum Hieron. dizziness test Tressens 6469 (CTES) CHA, COS, MIS, SAL Adiantum raddianum C. Leaf: abortive, antitussive, No biological Spores. Spermidine, N(1)-N(10)-caffeoyl-feruloyl: alkaloids Presl emmenagogue, to dissolve the mucus test Culantrillo, culandrillo and for respiratory disorders, Hunziker 10274 (CORD) diaphoretic, emollient BAI, CAT, CHA, COR, COS, ERI, JUJ, LRI, MIS, SAL, SFE, SLU, TUC Adiantum thalictroides Entire plant: abortive No biological No data var. hirsutum ( Hook. & Leaf: antitussive, abortifacient, to test Grev.) de la Sota dissolve the mucus and for Culantrillo respiratory disorders

Hunziker 8805 (CORD) CAT, COR, JUJ, LRI, SAL, SJU, TUC KURTZIANA Adiantum thalictroides Entire plant: abortive; against No biological Aerial parts. Adiantone: triterpene; β-sitosterol: ; p- Willd. ex Schltdl. var. menstrual disorders test methyl ester coumaric acid: phenylpropanoid thalictroides BAI, CAT, COR, JUJ, LPA, MEN, Culantrillo MIS, SAL, SJU, SLU, TUC Cantero et al. s.n. (R IOC 2768)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Argyrochosma nivea Plant: diaphoretic, diuretic, No biological No data (Poir.) Windham var. emmenagogue, laxative, respiratory test nivea disorders, for headaches and sinusitis Doradilla, tupasaire Leaf: sternutatory Stuckert 11714 (CORD) BAI, CAT, COR, JUJ, LPA, LRI, MEN, SAL, SDE, SJU, SLU, TUC Argyrochosma nivea var. Plant: diuretic Aerial parts: No data flava (Hook.) Ponce CAT, COR, JUJ, LRI, SAL, SJU, antioxidant Doradilla TUC activity Morero 37 (CORD) Cheilanthes buchtienii Aerial parts: abortifacient No biological No data (Rosenst.) R. M. Tryon BAI, CAT, COR, JUJ, LPA, LRI, test Doradilla blanca MEN, SAL, SJU, SLU, TUC Galián 43 (SI) Cheilanthes glauca (Cav.) Plant: diuretic, anti-catarrhal; Dried leaf: Dried entire plant. , : flavonols Mett. gynecological, obstretic antibacterial Doradilla CHU, NEU, RNE, SCR activity Chiapella 1708 (CORD) Cheilanthes marginata Plant: diaphoretic No biological No data Kunth CAT, COR, JUJ, LRI, SAL, SDE, test Doradilla TUC Morero 166 (CORD) Cheilantes myriophylla Plant: diaphoretic, respiratory No biological No data Desv. disorders test Doradilla floja del monte, Dried entire plant: used for cough, flor de piedra, doradillón diarrhea Stuckert 21162 (CORD) BAI, CAT, COR, JUJ, LPA, LRI, MEN, MIS, SAL, SJU, SLU, TUC Cheilantes obducta Mett. Root: for stomach-ache No biological No data ex Kuhn CAT, CHA, COR, FOR, JUJ, LRI, test Doradilla MIS, SAL, SDE, SJU, TUC Morero 59 (CORD) Doryopteris concolor Leaf: anthelmintic No biological Leaf. Squalene, zeorin, stigmasterol, β-sitosterol, (Langsd. & Fisch.) Kuhn BAI, CAT, COR, COS, ERI, FOR, test campesterol, friedelin: steroids; flavonol, , Helecho macho JUJ, MIS, SAL, SDE, SFE, SJU, triterpenoid 43 Novara 3633 (CORD) SLU, TUC

44

Hemionitis tomentosa Part not specified: for kidney pains No biological No data Tomo34(1-2):7-365.2009 (Lam.) Raddi and painful menstruation test Troncoso 3302 (SI) CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Pityrogramma Aerial parts, infusion: for fever and Dried aerial Aerial parts. Calomelanolactone: sesquiterpene calomelanos (L.) Link hypertension parts: cytotoxic Dried leaf. Calomelanol A, C, D, E, F, G, H, J, - var. calomelanos Dried entire plant, decoction: for and antibacterial 4'-7-dimethyl ether, chalcone-dihydro-2'-6'-dihydroxy-4'- Hierba de la seca, helecho respiratory and kidney disorders; activity methoxy, chalcone-2'-4-6'-trihydroxy-4'-methoxy, flavone- macho, gallito infusion: for stomach-ache, analgesic, Dried leaf: neo-dihydro 8-(phenyl-propionyl)-5-7-dihydroxy, flavone-8- Kurtz 6540 (CORD) astringent, expectorant, for venereal antifungal (2-carboxyl-1-phenyl-ethyl)-5-7-dihydroxy- δ lactone, disease, pectoral, emmenagogue, activity chalcone-2'-6'-dihydroxy-4-4'-dimethoxy: flavonoids febrifuge, antitussive Root: for stomach-ache Fruit: decoction, used for cuts, fever, hemorrhage, and hypertension BAI, COR, COS, JUJ, MIS, SAL, SDE, SFE SCHIZAEACEAE Anemia phyllitidis var. Entire plant: expectorant, Aerial parts Part not stated. Gibberellin: diterpene; β-ecdysone, tweediana (Hook.) Hassl. emmenagogue essential oil: ponasterone A: steroids; zeatin riboside, zeatin: alkaloids; Doradilla BAI, CHA, COS, MIS, SAL antimycobacteri antheridic acid: diterpene Deginani 1133 (SI) al activity Anemia tomentosa var. Leaf: antitussive, expectorant No biological Aerial parts essential oil. α-bisabolol, spathulenol, anthriscifolia (Schrad.) BAI, CAT, CHA, COR, COS, FOR, test caryophyllene oxide, α-bisaboloxide, 14-hydroxy-9-epi-(E)- Mickel JUJ, MIS, SAL, SDE, SFE, TUC caryophyllene, neral, geranial, α-pinene, camphene, 6- Doradilla methyl-5-hepten-2-one, 1,8-cineole, pinocarveol; Hunziker 13557 (CORD) isoafricanol Anemia tomentosa var. Leaf: antitussive, emmenagogue, No biological No data australis Mickel respiratory disorders test KURTZIANA Doradilla CAT, COR, JUJ, LRI, SAL, SDE, Luján 57 (CORD) SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Anemia tomentosa Fresh entire plant: for whooping No biological No data (Savigny) Sw. var. cough test tomentosa Dried branch + leaf, decoction: to Doradilla, yerba buena, treat urinary tract infections, yerba dorada, doradilla antidiarrheal aromática, doradilla Leaf: antitussive, diaphoretic, hembra emmenagogue, expectorant, Cantero et al. s.n. (RIOC abortifacient, contraceptive, to sooth 2123) menstrual pains and for respiratory disorders BAI, CAT, CHA, COR, COS, ERI, MIS, RNE, SAL, SDE, SLU, TUC SELAGINELLACEAE Selaginella convoluta Entire plant, infusion: aphrodisiac Plant: No data (Arn.) Spring FOR, MIS, SAL antidepressant Eyerdam 22909 (SI) effect 45

46

GYMNOSPERMAE Tomo34(1-2):7-365.2009

TAXA ETHNOMEDICAL BIOLOGICAL CHEMICAL DATA (Family, Latin Name, INFORMATION/ ACTIVITIES Vernacular Names, DISTRIBUTION Synonyms, Exiccatum) ARAUCARIACEAE Araucaria angustifolia Resin: balsamic, antiseptic Dried wood: Undifferentiated callus. E and Z isomers of octadecyl p- (Bertol.) Kuntze var. MIS anticercarial and coumarate, octadecyl ferulate angustifolia antifungal Fresh seedling. Amentoflavone,4'-4'''-di-O-methyl, Pino Paraná, curi, curiy, activity amentoflavone,4'-7-7''-tri-O-methyl: flavonoids curi-i Seedling stems. Biflavones of the amentoflavone-type Burkart 4944 (SI) Seedling roots. Trans-communic acid: diterpene Bark. Agathic acid: diterpene Dried heartwood. Chalcone,4-4'-dihydroxy: ; irisolidone, isoflavone Adult stems. , p-hydroxybenzaldehyde, coniferaldehyde: benzaldehydes; , eudesmin and lariciresinol: lignans; cabreuvine, irisolidone: Dried leaf. Agathisflavone, amentoflavone, cupressuflavone, kayaflavone, ginkgetin, tetra-O- methylamentoflavone: flavonoids Resin. Abieta-7-13-dien-18-oic acid: diterpene; 5- methoxylariciresinol-9-acetate, 5′-methoxylariciresinol-9- acetate, 5-methoxypinoresinol dimethyl ether, 5- methoxypinoresinol, lariciresinol acetates, 7′- hydroxylariciresinol acetates, isolariciresinol acetate, shonanin: lignans Araucaria araucana Resin: balsamic Resin: Resin. Imbricatolic acid, 15-hydroxyimbricatolal, 15-

(Molina) K. Koch NEU, RNE gastroprotective acetoxyimbricatolic acid: diterpenes KURTZIANA Piñon, pino de Neuquén activity and Wood. , pinoresinol, eudesmin, Pedersen 14149 (CTES, cytotoxic effect lariciresinol, lariciresinol-4-methyl ether: lignans SI) Wood: Essential oil. Geraniolene, limonene, (+)-γ-cadinene, (−)-α- antifungal and cadinol, (+)-hibaene, (−)-trachylobane, (−)-kaurene, (−)- antibacterial atisirene, isokaurene/isoatisirene. activity

BARBOZA, G.E.etal.MedicinalfloraofArgentina CUPRESSACEAE Austrocedrus chilensis Bark and leaf: antitussive and Aerial part: Aerial part. Taxodione, taxodone, fuerstione, (D. Don.) Serm. & diaphoretic citotoxic desoxypodophyllotoxin, pisiferol: diterpenes Bizzarri Fruits: antidiarrheal activity Bark. Sugiol: diterpene Ciprés de la Cordillera, CHU, NEU, RNE Bark: Wood. Podophyllotoxin: ciprés antibacterial Leaf essentials oils. α-pinene, myrcene, δ-3-carene Cocucci 967 (CORD) activity Fitzroya cupressoides Resin: balsamic and anti- No biological Dried leaf. Muurol-trans-5-en-3-α-ol, himachal-4-en-1-β-ol, (Molina) I. M. Johnst. inflammatory test α-pinene, spathulenol, (Z)-nerolidol, α-cadinol, cis- Alerce, lahuán, lahuén CHU, NEU, RNE calamenene Cocucci 409 (CORD) Dried branches + leaf. Cupressuflavone,7-7''-dimethyl, amentoflavone,4'''-monomethyl, cupressuflavone: flavonoid EPHEDRACEAE americana Dried aerial parts, infusion: Aerial parts: Aerial parts. Ephedrine, pseudo-ephedrine, N- Humb. & Bonpl. ex Willd. respiratory stimulant, diaphoretic, antiviral, anti- methylephedrine: alkaloids; tannins; flavonoids; hesperidine, Tramontana, tola, frutilla del anti-hemorrhagic, anesthetic, inflammatory and crisine, 5,7,3’-4’-tetrahydroxy-6,8’- flavone, 5,7,3’- campo, pingo pingo, pinco- digestive, diuretic, antiseptic, antimicrobial trihydroxy-6,4’-dimethoxy-flavonol, 4’-hydroxy-7-methoxy- pinco, san-san, sanu-sanu, diuretic, astringent, stomachic, anti- activity; immuno- 5-O-glucosyl-flavonone; soldaque, solda que solda, inflammatory, for fractures stimulating effect suelda consuelda, suelda CAT, COR, JUJ, LRI, SAL, SLU, Stem: cytotoxic que suelda TUC activity Cantero s.n. (RIOC 1598) Ephedra breana Phil. Plant: respiratory disorders, Aerial parts: Dried aerial parts. , apigeninidin: flavonoids; Tramontana, pingo pingo, cholagogue, diuretic, for kidney and antimicrobial ephedrine: alkaloid frutilla del campo, pico de stomach pains activity Young stem. loro Root, infusion: antiseptic Woody stem. Proapigeninidin Kurtz 3485 (CORD) Branch, infusion: diuretic, gastro- intestinal disorders; decoction: astringent CAT, JUJ, LRI, MEN, SAL, SJU, TUC Ephedra chilensis C. Aerial parts: antitussive, Aerial parts: Aerial parts. β-sitosterol; ephedrine, 2- (ethylhexanol) phthalate: Presl decongestant alternative; against antibacterial alkaloids (sub nom. E. andina) Tramontana asthma, liver and urinary bladder activity Root. Propelargonidin, proapigeninidin: proanthocyanidins Ephedra andina Poepp. discomforts Dried stem. Proline,3-4-methano, (2S,3S,4S)-2- ex C. A. Mey. CHU, MEN, NEU, RNE, SCR, SJU (carboxycyclopropyl)glycine: proteids; kynurenic acid,6- 47 Cocucci 3537 (CORD) hydroxy: quinoline alkaloid; prodelphinidin:

Ephedra frustillata Miers Medicinal No biological Dried aerial parts. Delphinidin , apigeninidin: flavonoids; 48 Tramontana CHU, NEU, RNE, SCR, TDF test proanthocyanidins Tomo34(1-2):7-365.2009 Barboza 1212 (CORD) Ephedra multiflora Phil. Part not specified: anti- No biological No data ex Stapf inflammatory, cholagogue, diuretic, test Tramontana, pingo pingo for kidney and stomach pains Hunziker 23868 (CORD) CAT, LRI, MEN, NEU, SAL, Ephedra ochreata Miers Aerial parts: for hair care Aerial parts: Aerial parts. Ephedrine, pseudo-ephedrine: alkaloids; Solupe, solupe frutero, Dried branch + leaf, infusion: antibacterial triterpenes; sterols; proanthocyanidins frutilla del quirquincho, bradicardic; decoction: against activity tramontana, quebracho diarrhea, and to treat respiratory tract flojo, fruta del pichi infections Cantero et al. s.n. (RIOC BAI, CAT, CHU, LPA, LRI, MEN, 3221) NEU, RNE, SCR, SJU, SLU Ephedra triandra Tul. Aerial parts: for hair care No biological Stem.Ephedrine: absent emend. J. H. Hunz. Dried branch + leaf: antidiarrheal, test Tramontana, pico de loro, anti-diabetic, antirheumatic, fruta del quirquincho, vulnerary, rubefacient, to treat pico de pajarito, pico de respiratory tract infections, blood gallo depurative, reduces uric acid Cantero et al. s.n. (RIOC Root, infusion: abortive 5265) BAI, CAT, CHA, COR, ERI, LPA, LRI, MEN, RNE, SAL, SDE, SFE, SJU, SLU, TUC Ephedra tweediana Dried entire plant: medicinal No biological Dried stem. Methano-proline, (2S,3S,4S)-2- Fisch. & C. A. Mey. BAI, CAT, COS, ERI, TUC test (carboxycyclopropyl)glycine: proteids; kynurenic acid,6- emend. J. H. Hunz. hydroxy: quinoline alkaloid Tramontana, transmontaña, pingo pingo, pico de loro Hunziker 17621 (CORD) PODOCARPACEAE Podocarpus parlatorei Medicinal No biological Essential oil. Terpinen-4-ol, germacrene D, α-eudesmol KURTZIANA Pilg. CAT, JUJ, SAL, TUC test Pino del cerro, pino, pino de Jujuy, pino tucumano, pino blanco, pino montano, pino criollo, pino de monte Venturi 2978 (SI)

ANGIOSPERMAE-MONOCOTYLEDONEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina

TAXA ETHNOMEDICAL BIOLOGICAL CHEMICAL DATA (Family, Latin Name, INFORMATION/ ACTIVITIES Vernacular Names, DISTRIBUTION Synonyms, Exiccatum) ALISMATACEAE Echinodorus grandiflorus Plant: stimulant, diuretic, Rhizome: Leaf essential oil. Phytol, (E)-caryophyllene, α-humulene, subsp. aureus (Cham. & antirheumatic, laxative, cholagogue, analgesic and (E)-nerolidol, linalool, dihydroedulan, (E)-farnesene, β- Schltdl.) Micheli hypocholesteremic, anti-syphifilitic anti- selinene, α-farnesene, γ-cadinene, caryophyllene oxide, Cucharero, cucharones, and astringent, for the treatment of inflammatory humulene epoxide, bisabolone, drimenol, neocembrene, cucharón high blood pressure and activity (sub nom. echinoic acid, cembranoid; echinodol: cembrene derivative Múlgura de Romero 2578 inflammatory diseases. E. grandiflorus) (sub nom. E. grandiflorus) (CORD) Leaf: bladder disease, wounds, anti- Leaf: diuretic, inflammatory hypotensive, and CHA, COS, MIS, SFE antibacterial activity; potent vasodilator effect Sagittaria montevidensis Rhizome + leaf: refrigerant, Leaf: antitumor Fresh petioles. Abietenes, 7,13-abietadien-3-one, 8,11,13- Cham. & Schltdl. febrifuge, rubefacient activity abietatrien-3-ol, 3b-hydroxy-9a, 13a-epidioxyabiet-8(14)- Saeta, pata de loro, achira, BAI, CHA, COR, COS, ERI, FOR, ene, 3-oxo-9a, 13a-epidioxyabiet-8(14)-ene sagitaria JUJ, MIS, SAL, SFE, TUC Hunziker 22391 (CORD) ALLIACEAE Tristagma patagonicum Part not specified: medicinal No biological No data (Baker) Traub CHU, MEN, NEU, RNE, SCR test Chaleo Cocucci 3487 (CORD) ALSTROEMERIACEAE Alstroemeria aurea Bulbs: hepatic affections; skin No biological Fresh flowers. Tulipalin A: lactone; tulipinoside A: alkene Graham affections (sub nom. A. aurantiaca) test Amancay, liuto, liuto Part not specified: emollient, amarillo, amancay, rayen- obstetric gynaecological cachu, huta, cascabel CHU, NEU, RNE Alstroemeria aurantiaca D. Don 49 Cocucci 2431 (CORD)

50

Alstroemeria patagonica Part not specified: medicinal No biological No data Tomo34(1-2):7-365.2009 Phil. CHU, NEU, RNE, SCR, TDF test Liuto Cocucci 452 (CORD) Bomarea edulis (Tussac) Part not specified: digestive, No biological Flowers. Tuliposide A: alkene Herb. stimulant, antidiarrheal test Salsilla CAT, JUJ, MIS, SAL, TUC Barboza 1144 (CORD) AMARYLLIDACEAE Habranthus chacoensis Bulbs: narcotic No biological No data Ravenna CHA test Kermes 538 (SI) Rhodophiala mendocina Part not specified: medicinal No biological No data (Phil.) Ravenna CHU, LPA, MEN, NEU, RNE test Cebolleta, ajo del diablo, cebolla de zorra Rhodophiala elwessii (C. H. Wright) Traub. Cano 1732 (BAB) Zephyranthes mesochloa Bulb: refrigerant No biological No data Herb. ex Lindl. BAI, CAT, COS, ERI, FOR, JUJ, test Cebolla de campo LRI, MIS, TUC Biganzoli 1430 (CORD) ARACEAE Anthurium paraguayense Plant: abortive No biological No data Engl. Leaf: cordial, abortifacient, test Calaguala emmenagogue Lorentz 543 (CORD) CHA, COS, FOR, SAL, TUC Gorgonidium vermicidum Part not specified: medicinal No biological No data KURTZIANA (Speg.) Bogner & Nicolson CAT, CHA, JUJ, MIS, SAL, TUC test Papa de víbora, gusanera, puqui, sacha col Schinini 32946 (CTES)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Philodendron Leaf: heal, hemostatic, for Leaf: No data bipinnatifidum Schott ex conjunctivitis antiprotozoal Endl. COS, MIS activity Guembé, iva-embé, potota Rhizome resin: Cocucci 3215 (CORD) antinociceptive activity Philodendron Leaf: Medicinal No biological No data tweedianum Schott CHA, COS, ERI test Guembé, filodendro, guembetaya Pedersen 13462 (SI) Philodendron undulatum Hanging root: Ringworm, No biological No data Endl. dermatitis test Guaembé, güembé, güembé COS, ERI, MIS espinoso Tressens et al. 4195 (CTES) Pistia stratiotes L. Entire plant, decoction: Dried entire Dried entire plant. α-asarone: phenylpropanoid; linolenic Lechuga cimarrón, repollito emmenagogue; diuretic, pectoral, plant: calcium acid: lipid; 24(s)-ethyl cholesta-4-22-diene-3-6-dione: del agua, llantén del agua, emollient channel blocker; steroid; lucenin, chrysanthemin, luteolin-7-, lechuga del agua Leaf, infusion: to treat sterility and bronchodilator, vicenin: flavones; stigmasterol stearate: steroid Hunziker 25425 (CORD) diabetes; anti-haemorrhoidal, anticrustacean, ophtalmic, abluent antileishmanial BAI, CHA, COS, ERI, FOR, JUJ, and antibacterial MIS, SAL, SFE, TUC activity Spathicarpa hastifolia Leaf: antineoplasic No biological No data Hook. CHA, COS, JUJ, MIS, SAL, SFE, test Pata de loro, yuyo cure, TUC sacha col, aguacnote, caaité, coa-ité, güembé Zardini et al. 14264 (CORD)

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ARECACEAE 52 Acrocomia aculeata Stem: febrifuge No biological Leaf. Flavonoids Tomo34(1-2):7-365.2009 (Jacq.) Lodd. ex Mart. Root, infusion, decoction: test Fruit. β-carotene Coco, cocotero, mbocayá o abortifacient, emmenagogue (sub Fruit kernels. Globulins, glutelins, albumin, prolamin: nuez del Paraguay nom. A. totai); diuretic proteins; aspartic acid, glutamic acid, serine, , glycine, Acrocomia totai Mart. Seeds: tonic stimulant, vermifuge, , arginine, threonine, alanine, proline, valine, Xifreda 1286 (SI) for myopia methionine + cisteyne, isoleucine, leucine, phenylalanine + Young plant: diuretic, for lowering , lysine: amono acids; calcium, magnesium, blood pressure phosphorus, potassium, sodium, iron, manganese, zinc, Fruit oil: analgesic cooper: minerals; caprylic acid, capric acid, lauric acid, Seed oil: laxative myristic acid, palmitic acid, stearic acid, oleic acid, linoleic COS, FOR, MIS, SAL acid: lipids Butia paraguayensis Seeds: vermifuge No biological No data (Barb. Rodr.) L.H. Bailey COS, MIS test Yataí poñí Marcato 320 (SI) Butia yatay (Mart.) Becc. Seeds: vermifuge No biological Kernel oil. Dodecanoic acid, octadecanoic acid, decanoic Yataí, yatay, coco, arirí, CHA, COS, ERI, MIS, SFE test acid, 9-octadecenoic acid palma yatay Zuloaga 5674 (SI) Copernicia alba Morong Seeds: anthelmintic No biological No data Carandá , palmera carandá, CHA, COS, FOR, JUJ, SAL, SDE, test caranday, palma espinillo, SFE palma blanca Fortunato 1370 (BAB) Syagrus romanzoffiana Leaf: cephalalgic Dried pericarp: Dried pericarp. α-myrin, betulin, cholesterol (steroids): (Cham.) Glassman Root: contraceptive antihyperglyce triterpenes; β-carotene: carotenoid; caproic acid: lipid Pindó, dátil, palma del Part not specified: odontalgic, mic activity Kernel oil. Dodecanoic acid, octadecanoic acid, decanoic monte, chiri vá cicatrizant acid, 9-octadecenoic acid Reitz 1878 (SI) BAI, CHA, COS, ERI, FOR, MEN, KURTZIANA MIS, SFE, SJU, SLU BROMELIACEAE Aechmea distichantha Flowers: anti-ulcer stomachic No biological No data Lem. CAT, CHA, FOR, JUJ, SAL test Cardo chuzo, caraguatá payo, caraguatá chuza Cocucci 3204 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Bromelia balansae Mez Fruit: antidiarrheal Unripe fruit: Unripe fruit. Balansain I: endopeptidase Caraguatá Part not specified: emmenagogue enzymatic Fruit juice. Balansain: proteid Barboza 389 (CORD) COS, FOR, MIS activity Fruit gum. Galactose, , xylose: sugars Bromelia hieronymi Mez Parenchyma: stimulant No biological Unripe fruit. Hieronymain I, II, III: cysteine peptidase Chaguar blanco, cardo CHA, FOR, JUJ, SAL, SDE, TUC test Fruit gum. Galactose, arabinose, xylose, glucuoronic acid, gancho blanco galacturonic acid-xylose: sugars Bernardello 499 (CORD) Bromelia serra Griseb. Fruits: antidiarrheal, anti-emetic No biological Fruit gum. Galactose, arabinose, xylose, galacturonic acid- Caraguatá, cardo gancho, : anthelmintic test xilose: sugars cháguar Fruit: anti-emetic Bernardello 418 (CORD) CHA, COR, COS, FOR, JUJ, SAL, SDE, SFE, TUC Bromelia urbaniana (Mez) Part not specified: medicinal No biological No data L.B. Sm. CAT, CHA, COR, FOR, LRI, MEN, test Chaguar; caraguatá SAL, SDE, SFE, SLU, TUC Deinacanthon urbanianum (Mez) Mez Hunziker 21305 (CORD) Tillandsia aëranthos Aerial parts: analeptic (CNS Aerial parts: No data (Loisel.) L.B. Sm. stimulant), diuretic antimicrobial Clavel del aire BAI, CAT, COR, COS, ERI, JUJ, activity Venturi 237 (SI) MIS, SAL, SGO, SFE, TUC Tillandsia australis Mez Part not specified: medicinal No biological No data Payo JUJ, SAL, TUC test Lorentz 539 (CORD) Tillandsia bandensis Baker Entire plant: diuretic No biological No data Clavel del aire BAI, CAT, CHA, COR, COS, ERI, test Subils et al. 3315 (CORD) FOR, JUJ, LRI, SAL, SDE, SFE, TUC Tillandsia bryoides Griseb. Leaf: astringent, vulnerary, tonic No biological No data ex Baker emend. L.B. Sm. stimulant test Clavel del aire BAI, CAT, CHU, COR, JUJ, LPA, Hunziker et al. 21743 LRI, MEN, RNE, SAL, SDE, SFE, (CORD) SJU, SLU, TUC 53

54

Tillandsia capillaris Ruiz Leaf: tonic stimulant No biological No data Tomo34(1-2):7-365.2009 & Pav. f. capillaris CAT, COR, JUJ, LRI, MEN, SAL, test Clavel del aire SJU, TUC Subils et al. 3262 (CORD) Tillandsia capillaris f. Entire plant: cordial Dried aerial Fresh entire plant. Cycloartanol, 24-methylene cordobensis (Hieron.) Dried aerial parts, infusion: parts: cycloartanol: triterpenes L.B.Sm. antispasmodic, and for eye infections antibacterial Clavel del aire BAI, CAT, CHA, COR, JUJ, LRI, activity Tillandsia recurvata (L.) L. SAL, SDE, SLU, TUC Biurrun 4898 (CORD) Tillandsia capillaris f. Leaf: astringent, vulnerary No biological No data virescens (Ruiz & Pav.) (sub nom. T. pusilla). test L.B. Sm. BAI, COR, JUJ, LRI, MEN, SAL, Clavel del aire SDE, TUC Tillandsia pusilla Gillies ex Baker Subils 4352 (CORD) Tillandsia duratii var. Entire plant: contraceptive No biological No data saxatilis (Hassl.) L. B. Sm. CHA, COS, FOR, SFE test Clavel del aire Hunziker 7777 (CORD) Tillandsia loliacea Mart. Leaf: kidney inflammation No biological No data ex Schult. f. CHA, COR, COS, FOR, JUJ, MIS, test Jörgensen 3396 (SI) SAL, SDE, SFE, TUC Tillandsia meridionalis Entire plant, decoction: No biological No data Baker contraceptive, cordial test Clavel del aire CHA, COS, ERI, FOR, JUJ, MIS, Subils 3147 (CORD) SAL, SFE, TUC

Tillandsia myosura Leaf: astringent, vulnerary No biological No data KURTZIANA Griseb. ex Baker CAT, COR, JUJ, LRI, MEN, SAL, test Subils et al. 2965 (CORD) SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Tillandsia streptocarpa Entire plant, decoction: Dried aerial Dried entire plant. Cycloartenol: triterpene; 1-O-p- Baker contraceptive parts: anti- coumaroyl-3-O-feruloylglycerol; 1,3-O-dicaffeoylglycerol; Zuloaga 6472 (SI) COS, MIS inflammatory, 1-O-p-coumaroyl-3-O-caffeoylglycerol; 1-O-feruloyl-3-O- antioedematoge caffeoylglycerol: phenylpropanoid glycerols; stigmasterol, nic, free radical β-sitosterol, campesterol: steroids scavenging and antimicrobial activity Tillandsia usneoides (L.) Dried aerial parts, infusion: Entire plant: Entire plant. (22E)-25,26,27-trisnor-3-oxocycloart-22-en- L. antispasmodic, diuretic, estrogenic and 24-al, (24E)-3-oxocycloart-24-en-26-al, 24-hydroxycycloart- Barba de viejo, barba del antihypertensive, anticonceptive; to androgenic 25-en-3-one, (23E)-25-methoxycycloart-23-en-3-one, (23E)- monte, cabello de ángel, treat rheumatism, anti-haemorrhoids, effect; 25-hydroperoxycycloart-23-en-3-one, 25,26,27-trisnor-24- barba de tabaquillo, clavel and symptoms of diabetes mellitus; hypoglycemic, hydroxycycloartan-3-one, methyl (24E)-26-carboxy-3,4- del aire, barbón, peluca, for pulmonary and heart diseases, antitumor, seco-cycloart-4(29),24-dien-3-oate, methyl (23E)-25- Hunziker 18844 (CORD) and eye infections antibacterial and hydroxy-3,4-seco-cycloart-23-en-3-oate, methyl (23E)-25- Leaf: astringent, anti-haemorrhoidal, antiviral activity methoxy-3,4-seco-cycloart-23-en-3-oate, methyl 24- choleretic, cholagogue, Fresh leaf: hydroxy-3,4-seco-cycloart-25-en-3-oate: cycloartane antirheumatic, hypoglycemic, analgesic derivatives against toothache activity Leaf + stem. 4'-5-7-trihydroxy-3-3'-5'-6-tetramethoxy BAI, CAT, CHA, COR, COS, FOR, flavone; 4'-5-7-trihydroxy-3-3'-5'-6-tetramethoxy: flavonol; JUJ, MIS, SAL, TUC -3-3'-4'-7-tetramethyl ether: flavonol; citric acid, succinic acid, 3-hydroxy-3-methylglutaric acid Dried aerial parts. Sterols, phenols and triterpenes Tillandsia vernicosa Leaf: kidney inflammation No biological No data Baker CHA, COR, COS, FOR, JUJ, SAL test Venturi 201 (SI) Tillandsia xiphioides Ker Flowers: cordial No biological No data Gawl. var. xiphioides BAI, CAT, COR, JUJ, LPA, LRI, test Margarita, clavel del aire, MEN, MIS, SAL, SDE, SJU, SLU, flor del aire TUC Hunziker 13706 (CORD) Vriesea friburgensis var. Part not specified: medicinal No biological No data tucumanensis (Mez) L. B. CAT, CHA, COS, FOR, JUJ, MIS, test Sm. SAL, TUC

Payo 55 Bernardello 940 (CORD)

CANNACEAE 56 Canna glauca L. var. Rhizome: diuretic, diaphoretic, anti- No biological No data Tomo34(1-2):7-365.2009 glauca inflammatory test Achira, achira amarilla Leaf, rhizome and root: Hunziker 19019 (CORD) antirheumatic, pediluvium Seeds: against the earache BAI, CHA, COS, ERI, FOR, JUJ, MIS, SFE COMMELINACEAE Commelina erecta var. Aerial parts: conceptive No biological No data angustifolia (Michx.) BAI, CHA, COS, ERI, FOR, JUJ, test Fernald f. angustifolia MIS, SFE Flor de Santa Lucía Hunziker 18079 (CORD) Commelina erecta L. var. Entire plant, infusion: fecundity- Whole plant: Aerial parts. Steroids, tannins, mucilage, oxidases erecta f. erecta promoting giardicidal Yerba de Santa Lucía, flor Aerial parts: for treat wounds activity de Santa Lucía externally Dried flowers: Hunziker 15383 (CORD) Flowers: ophtalmic, hemostatic, antibacterial against the herpes; infusion: for eye activity infections and hepatic disorders Dried leaf, infusion: diuretic BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, SJU, SLU, TUC Commelina platyphylla Flowers: ophthalmic No biological No data Klotzsch ex Seub. CHA, COS, ERI, FOR, MIS test Santa Lucía Barboza 1550 (CORD)

Dichorisandra hexandra Part not specified: galactagogue No biological No data KURTZIANA (Aubl.) Standl. COS, JUJ, MIS, SAL test Deginani 1695 (SI) Tradescantia fluminensis Flowers: ophtalmic Dried aerial No data Vell. BAI, CHA, COR, COS, ERI, FOR, parts: α- Tradescansia JUJ, MIS, SAL, SFE, TUC glucosidase Santa Lucía blanca inhibition Hunziker 17655 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Tripogandra diuretica Flowers, decoction: ophtalmic No biological No data (Mart.) Handlos BAI, ERI, FOR, MIS, SFE test Santa Lucía rosada Morrone 2037 (SI) Tripogandra glandulosa Flowers: ophtalmic No biological No data (Seub.) Rohweder BAI, CAT, CHA, COR, COS, ERI, test Hunziker 10803 (CORD) FOR, MIS, SAL, SFE, TUC CYPERACEAE Abildgaardia ovata (B urm. Root: cephalalgic No biological No data f.) Kral CHA, COS, ERI, FOR, JUJ, MIS, test Pedersen 6213 (SI) SAL, SFE, TUC Bulbostylis capillaris (L.) Aerial parts: contraceptive No biological No data C.B. Clarke var. capillaris BAI, CAT, CHA, COR, COS, ERI, test Hunziker 8325 (CORD) FOR, LRI, MIS, SAL, SDE, SFE, SLU, TUC Cyperus aggregatus Rhizome: diuretic, antinephritic, No biological No data (Willd.) Endl. var. febrifuge, diaphoretic test aggregatus BAI, CAT, CHA, COR, COS, ERI, Cantero et al. s.n. (RIOC FOR, JUJ, LPA, LRI, MIS, SAL, 3858) SDE, SFE, SJU, SLU, TUC Cyperus entrerianus Entire plant: abortive, refrigerant No biological No data Boeck. var. entrerianus BAI, CAT, CHA, COR, COS, DFE, test Piripiri, piri piri de víbora ERI, FOR, JUJ, MIS, SAL, SDE, Deginani 1394 (SI) SFE, TUC Cyperus esculentus var. Entire plant: aphrodisiac Rhizome: Tuber. Arginine, alanine: amionacids; 5-dehydro- leptostachyus Boeck. Stem and rhizome: emollient, uterine avenasterol: steroid; behenic acid: lipid; cycloartenol: Chufa salvaje stomachic, emmenagogue, stimulant effect triterpene; β-sitosterol:steroid Cantero et al. s.n. (RIOC refrigerant, carminative Fruit: Seed oil. Arachidic acid: lipid 731) Dried rhizome, infusion: to treat antioxidant Essential oil. α-pinene, α-thujene and others epilepsy, and stomachache (sub nom. activity (sub nom. C. esculentus) C. esculentus) (sub nom. C. BAI, CAT, CHA, COR, COS, DFE, esculentus). ERI, FOR, JUJ, MIS, SAL, SDE, SFE, SJU, TUC 57

Cyperus friburgensis Leaf: against dyspepsia No biological No data 58 Boeck. JUJ, MIS, SAL test Tomo34(1-2):7-365.2009 Yunga yunga Schinini 28274 (CTES) Cyperus giganteus Vahl Powdered stem: hemostatic Fresh entire Rhizome essential oil. Cyperotundone, cyperene, Papiro criollo, pirí, totora BAI, CHA, COS, ERI, FOR, MIS, plant: cyperenone, isopatchou-4(5)en-3-one, patchoulane, epoxy- Schinini 27533 (CTES) SFE, TUC molluscicidal cyperene activity Part not specified. Flavonoids, , triterpenoids Cyperus luzulae (L.) Entire plant: refrigerant; infusion: Dried root: No data Rottb. ex Retz. antidiarrheal and for stomachaches molluscicidal Correa 5168 (BAB) Dried root: for ophthalmic and cytotoxic infections activity CHA, FOR, SAL, TUC Cyperus odoratus L. Rhizome: aphrodisiac, nutritive Entire plant: Dried inflorescence. Luteolin, tricin: flavone Hunziker 7588 (CORD) tonic insect repellent Part not specified: emmenagogue activity BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, TUC Cyperus redolens Maury Entire plant: contraceptive No biological No data Hunziker 12017 (CORD) BAI, CHA, COR, COS, ERI, JUJ, test SFE Cyperus reflexus Vahl Rhizome: diuretic, antinephritic, No biological Dried inflorescence + leaf. Luteolin, tricin: flavones Hunziker 16616 (CORD) febrifuge, diaphoretic test BAI, CHA, COR, COS, ERI, FOR, LPA, MIS, RNE, SFE, SLU, TUC Cyperus rotundus L. Dried entire plant, infusion: for all Entire plant: Essential oil. γ-cadinene, 1,8-cineol, α-copaene, cyperene, Cebollón, castañuela, types of fever, anti-inflammatory antipyretic, β-cyperone, α-cyperone; caryophyllene, cyperenone, júncea, pasto bolita, pasto agent; anti-emetic, astringent, antifungal, cyperol, cyperolone, cyperotundone, β-elemene, α- KURTZIANA bolilla, negrillo, cebollín analgesic, antitussive, and for antibacterial, humulene, isocyperol, kobusone, mustakone, rotundene, Lallana 1899 (CORD) indigestion hypotensive, rotundol, α-rotundol, β-rotundol, β-silenene: sesquiterpenes; Rhizome: aphrodisiac, astringent, antioxidant, p-coumaric acid, , p-hydroxybenzoic acid, nutritive tonic, for the treatment of antihyperglyce , vanillic acid dysmenorrhoea and menstrual mic, anti- Aerial plant. Chrysoeriol: flavone; N-(1-deoxy-α-D- irregularities inflammatory, fructos-1-yl)-L-tryptophan and its tautomers: fructose-amino

BARBOZA, G.E.etal.MedicinalfloraofArgentina Cyperus rotundus L. BAI, CHA, COR, COS, DFE, ERI, free radical acid conjugate; n-butyl-β-D-fructopyranoside, ethyl-α-D- (continuation) JUJ, LPA, MEN, MIS, SAL, SDE, scavenging, and glucopyranoside, adenosine, (-)-(E)-caffeoylmalic acid, vitexin, SFE, SJU, TUC α-amylase isovitexin, orientin, epiorientin, myricetin 3-O-β-D- inhibitory activity galactopyranoside, luteolin 7-O-β-D-glucuronopyranoside-6''- Tuber essential methyl ester, chlorogenic acid, luteolin 4'-O-β-D- oil: antibacterial, glucuronopyranoside, luteolin 7-O-β-D-glucuronopyranoside, antimutagenic uridine, activity Tuber essential oil. Cyperene, cyperorotundene, rotundene, oc-cyperone, cyperol Cyperus spectabilis var. Leaf: against hepatic affections No biological No data jujuyensis Kük. JUJ, SAL test Cuatro cantos Hunziker 1665 (SI) Eleocharis bonariensis Entire plant: pectoral No biological No data Nees BAI, CAT, CHA, COR, COS, DFE, test Junquillo ERI, JUJ, LPA, LRI, MEN, MIS, Cantero et al. s.n. (RIOC 771) RNE, SAL, SFE, SJU, SLU, TUC Kyllinga brevifolia Rottb. Leaf: digestive Dried rhizome: Dried entire plant. Vitexin: flavone Zuloaga 1502 (SI) Dried rhizome: sedative, CNS effects; Dried inflorescence. : flavonoid antispasmodic, diuretic respiratory Dried root: for liver disease depressant; BAI, CHA, COS, ERI, MIS, SFE, TUC acute toxicity Kyllinga odorata Vahl Leaf and rhizomes: diaphoretic, No biological Essential oil. Dihydrokaranone, aristolochene Cantero et al. s.n. (RIOC diuretic, antispasmodic, digestive, test 3525) antidiarrheal BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SCR, SFE, TUC Kyllinga vaginata Lam. Leaf: digestive No biological No data Zuloaga 6893 (SI) BAI, CHA, COS, ERI, MIS, SFE, TUC test Schoenoplectus Ash: hemostatic Aerial parts: No data californicus (C. A. Meyer) BAI, CAT, CHA, CHU, COR, COS, antibacterial Soják var. californicus DFE, ERI, FOR, JUJ, LPA, MEN, activity Totora, caballitos, junco, NEU, RNE, SAL, SCR, SDE, SFE, junco de laguna SJU, SLU, TDF, TUC Cantero et al s.n. (RIOC 59 3390)

DIOSCOREACEAE 60 Dioscorea campestris Tubers, infusion or decoction: for No biological No data Tomo34(1-2):7-365.2009 Griseb. rheumatism and diabetes test Mecho acá CHA, COS, ERI, FOR, MIS, SAL, Múlgura de Romero 1698 (SI) TUC Dioscorea glandulosa Root: lynphatic disorders No biological Dried tuber. Flavonoids Klotzsch ex Kunth Leaf: antimalarial test Zarza mandió CHA, MIS Kurtz 12447 (CORD) Dioscorea furcata Griseb. Tuber: diuretic No biological No data Krapovickas 31389 (BAB) COS, ERI, MIS test Dioscorea sinuata Vell. Part not specified: medicinal No biological No data Carapé, carachi BAI, CHA, COS, MIS, SAL test Hunziker 1540 (CORD) Dioscorea subhastata Vell. Tubers, infusion or decoction: for No biological No data Mecho acá rheumatism and diabetes test Dioscorea guaranitica (sub nom. D. guaranitica) Chodat et Hassl. CHA, COS Schulz 54 (SI) HERRERIACEAE Herreria bonplandii Root: antacid, digestive, diuretic No biological No data Lecomte BAI, CHA, COS, ERI, FOR, MIS, test Zarzaparrilla SFE Hunziker et al. 15498 (CORD) Herreria montevidensis Root, decotion: digestive, hepatic, Klotzsch ex Griseb. diuretic, antinephritic, for venereal No biological No data Zarzaparrilla blanca, zarza disease test blanca BAI, COS, ERI, FOR, JUJ, MIS, Novara et al. 9192 (CORD) SAL, SLU IRIDACEAE KURTZIANA Cypella herbertii (Lindl.) Entire plant: against the earache No biological Fresh seed. 3-(3'-carboxy-phenyl)-alanine: proteid Herb. subsp. herbertii BAI, COS, ERI, SFE test Irisito amarillo, mariquita, oreja de gato, lirito amarillo Cantero et al. s.n. (RIOC 3306)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Eleutherine bulbosa Bulbs: improve memory Bulb: Bulb. Eleutherin, naphthopyran, eleutherinol: (Mill.) Urb. JUJ, SAL, TUC. antibacterial, sesquiterpenoid; eleutherinone [8-methoxy-1-methyl-1,3- Lorentz 1163 (CORD) antifungal, dihydro-naphtho(2,3-c)furan-4,9 -dione]: naphthoquinone; antifertility, eleutherin [9-methoxy-1(R),3(S)-dimethyl-3,4-dihydro-1H- cicatrizant, and benzo(g)isochromene-5,10-dione], isoeleutherin [9- cytotoxic methoxy-1(R),3(R)-dimethyl-3,4-dihydro-1H- activity benzo(g)isochromene-5,10-dione], eleutherol [4-hydroxy-5- methoxy-3(R)-methyl-3H-naphtho(2,3-c)furan-1 -one]: quinonoid compounds Libertia chilensis (Molina) Part not specified: medicinal No biological No data Gunckel NEU test Trique-trique, thekel-thekel Cocucci 883 (CORD) Olsynium junceum (E. Leaf: abortifacient No biological No data Mey. ex C. Presl) Goldblatt BAI, CAT, CHU, JUJ, MEN, NEU, test Cocucci 3489 (CORD) RNE, SAL, SCR, SJU, TDF Sisyrinchium arenarium Part not specified: antineoplasic No biological No data Poepp. CHA, CHU, MEN, NEU, RNE, SCR test Tamascán, triqui-triqui Cocucci 2451 (CORD) Sisyrinchium chilense Entire plant: tonic, digestive, No biological No data Hook. carminative test Marancel, canchalaga Leaf: antitussive, pectoral, Cocucci 1207 (CORD) cholagogue BAI, CAT, CHA, COR, COS, ERI, JUJ, LRI, MEN, MIS, NEU, SAL, SCR, SFE, SJU, SLU, TDF, TUC Sisyrinchium Part not specified: antitussive, Dried entire No data macrocarpum Hieron. pectoral, cholagogue plant: Marancel CAT, CHU, LRI, MEN, RNE, SJU antibacterial Cocucci 64 (CORD) activity Sisyrinchium Entire plant: depurative No biological No data pachyrhizum Baker subsp. BAI, CAT, CHA, COR, COS, ERI, test pachyrhizum FOR, MEN, MIS, SAL, SDE, SFE, Cocucci 71 (CORD) SLU, TUC 61

62

Sisyrinchium vaginatum Entire plant: against toothache, Dried No data Tomo34(1-2):7-365.2009 Spreng. subsp. vaginatum bitter and to aid and promote branches: Canchalagua menstruation anticrustacean Cabrera 29403 (SI) Dried branches: febrifuge activity Dried leaf, decoction: sedative, carminative, diuretic, eupeptic, against urinary diseases BAI, COS, ERI, MIS JUNCACEAE Juncus acutus subsp. Fruit: antidiarrheal, hemostatic, Fresh entire Dried aerial parts. 5-(1-Ethoxy-ethyl)-2-hydroxy-7- leopoldii (Parl.) Snogerup diuretic, for insomnia plant: methoxy-1,8-dimethyl-9,10-dihydrophenanthrene, 5-(1- Junco, hunco, junquillo, Leaf, decoction: for respiratory antiphage, anti- phytoxy-ethyl)-2-hydroxy-7-methoxy-1,8-dimethyl-9,10- junco bravo, unquillo, unco problems eczematic dihydrophenanthrene, 2,7-dihydroxy-1-methyl-5- negro (sub nom. J. acutus) activity (sub vinylphenanthrene, 2,7-dimethoxy-1,6-dimethyl-5- Hunziker 9381 (CORD) BAI, COR, LPA, LRI, MEN, RNE, nom. J. acutus) vinylphenanthrene, 2,7-dihydroxy-1,6-dimethylpyrene: SAL, SFE, SJU, SLU, TUC phenanthrenes; oxyresveratrol 2-O-β-D-glucopyranoside, 3′,4′-O,O′-di-β-D-glucopyranoside, markhamioside F, canthoside B, glucorhamnoside: phenolic glycosides (sub nom. J. acutus) Dried rhizome. Benzo [5a-8a]-6-hydroxy-methyl- 5-vinyl: coumarins Juncus balticus var. Part not specified: medicinal No biological No data mexicanus (Willd.) (sub nom. J. balticus var. montanus) test Balslev BAI, CAT, CHU, COS, JUJ, LRI, Cabrera 20230 (SI) MEN, MIS, NEU, RNE, SAL, SCR, SFE, SJU, TDF, TUC Juncus pallescens Lam. Entire plant, decoction: No biological No data Junquillo emmenagogue test Hunziker 9617 (CORD) BAI, CAT, CHU, COR, COS, DFE,

ERI, MEN, NEU, RNE, SFE, SJU, KURTZIANA SLU, TUC Luzula correae Barros Part not specified: medicinal No biological No data San Juanito SCR test Correa 2962 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina LIMNOCHARITACEAE Hydrocleis nymphoides Leaf: refrigerant No biological No data (Willd.) Buchenau BAI, CHA, COS, ERI, FOR, SFE, test Camalotillo TUC Hunziker 5922 (CORD) ORCHIDACEAE Aspidogyne kuczynskii Part not specified: for injures No biological No data (Porsch) Garay CHA, COS, MIS test Hunziker 11040 (SI) Brachystele camporum Root: diuretic, purgative No biological No data (Lindl.) Schltr. BAI, CHA, COS, ERI, MIS test Zarzaparrilla de hoja Lorentz 1128 (CORD) Brachystele unilateralis Part not specified: diuretic, No biological No data (Poir.) Schltr. carminative test Nuil CHU, RNE Pérez-Moreau s.n. (SI) Catasetum fimbriatum Pseudobulb: emmenagogue, No biological No data (C. Morren) Lindl. & abortifacient test Paxton subsp. fimbriatum COS, FOR, JUJ, MIS, SAL Casco romano Cocucci 3220 (CORD) Cyclopogon elatus (Sw.) Roots: refrigerant, antirheumatic, No biological No data Schltr. venereal diseases, cephalalgic, test Zarzaparrilla de hoja, epilepsy, for dizziness orquídea de talar BAI, CHA, COR, COS, ERI, JUJ, Hunziker 6878 (CORD) MIS, SAL, SDE, SFE, TUC Cyrtopodium palmifrons Pseudobulb: pulmonary disorders, No biological No data Rchb. f. & Warm. emmenagogue, to treat urinary tract test Calaguala, calaguala infections, antidiarrheal macho COS, MIS Morrone 1250 (SI) Cyrtopodium pflanzii Entire plant: for cough No biological No data Schltr. TUC test 63 Martínez 341 (CORD)

Eltroplectris Root: for dizziness No biological No data 64 Tomo34(1-2):7-365.2009 schlechterana (Porto & MI test Brade) Pabst Orquidia Correa 5965 (BAB) Geoblasta pennicillata Part not specified: diuretic No biological No data (Rchb. f.) Hoehne ex M.N. BAI test Correa Orquídea de las sierras Burkart 4838 (SI) Oeceoclades maculata Roots: depurative No biological No data (Lindl.) Lindl. CHA, COS, FOR, JUJ, MIS, SAL, test Calaguala SFE Arbo 7822 (CTES) Oncidium bifolium Sims Pseudobulb, decoction: analgesic, No biological No data Calaguala, flor de pajarito abortifacient, emmenagogue test Zuloaga 5219 (SI) Leaf: nutritive tonic, refrigerant, galactagogue, venereal diseases and antinephritic BAI, CAT, CHA, COS, ERI, FOR, JUJ, MIS, SAL, TUC Oncidium pulvinatum Pseudobulb: refrigerant No biological No data Lindl. COS, MIS test Calaguala Burkart 1492 (SI) Trichocentrum pumilum Pseudobulb: refrigerant, cordial No biological No data (Lindl.) M.W. Chase & CHA, COS, FOR, MIS, SFE test N.H. Williams Calaguala

Múlgura de Romero 2716 KURTZIANA (SI) POACEAE Andropogon bicornis L. Root: diuretic, febrifuge No biological No data Cola de zorro, cola de Rhizome: diuretic, sudorific, for beri test caballo, rabo de zorro beri and hepatitis Pedersen 5503 (CORD) CHA, COS, MIS

BARBOZA, G.E.etal.MedicinalfloraofArgentina Anthoxanthum Root: aperitive, diuretic, refrigerant No biological No data utriculatum (Ruiz & Pav.) NEU test Y. Schouten & Veldkamp Paja ratonera Hierochloe utriculata (Ruiz & Pav.) Kunth Boelcke 10783 (SI) Aristida mendocina Phil. Entire plant, decoction: No biological No data Flechilla, flechilla crespa, contraceptive, oxytocic test saetilla BAI, CAT, CHA, COR, FOR, JUJ, Hunziker 19910 (CORD) LPA, LRI, MEN, RNE, SAL, SDE, SJU, SLU, TUC Aristida pallens Cav. Root and rhizome: bitter tonic, No biological No data Hunziker 18941 (CORD) diuretic, aphrodisiac, emollient test BAI, CHU, COR, COS, ERI, LPA, MEN, MIS, RNE, SFE, SLU Axonopus compressus Part not specified: for whooping No biological No data (Sw.) P. Beauv. cough test Nudillo, zacate amargo, Root: diuretic, antiphlogistic pasto chato, pasto jesuita, BAI, CHA, COR, COS, DFE, ERI, grama JUJ, MIS, SAL, SFE, TUC Hunziker 11972 (CORD) Bothriochloa exaristata Part not specified: alexipharmic No biological No data (Nash) Henrard CHA, COS, DFE, ERI, FOR, MIS, test Scrivanti 143 (CORD) SFE Bouteloua simplex Lag. Part not specified: febrifuge No biological Plant. Flavonoids Brama CAT, COR, JUJ, LRI, MEN, SAL, test Cialdella 306 (SI) SDE, TUC Bromus catharticus Vahl Part not specified: purgative Dried seed: β- Fresh leaf + stem. Cynaroside: flavone Cebadilla criolla, cebadilla BAI, CAT, CHA, CHU, COR, COS, glucuronidase australiana, cebadilla DFE, ERI, FOR, JUJ, LPA, LRI, inhibition pampeana, pasto de perro, MEN, MIS, NEU, RNE, SAL, SDE, cebadilla del cerro, grama SFE, SJU, SLU, TUC de las sierras

Cantero et al. s.n. (RIOC 65 2535)

6

Cenchrus echinatus L. Aerial parts: hypotensive, Root + seed: Root + seed. Palidol, carasiphenol C, nepalensinol B Tomo34(1-2):7-365.2009 Cadillo, roseta, cadillo, cardioactive antioxidant and pasto camelo, correntino, Entire plant, decoction: for skin anti- flechilla eczemas inflammatory Caro 3012 (CORD) Root, infusion: antimalarial, activity refrigerant BAI, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, MIS, SAL, SDE, SFE, TUC Cenchrus incertus M. A. Entire plant: hypotensive, No biological No data Curtis cardioactive test Roseta (sub nom. C. pauciflorus) Cenchrus pauciflorus BAI, CAT, CHA, COR, COS, ERI, Benth. JUJ, LPA, MEN, NEU, RNE, SAL, Ariza Espinar 734b SDE, SLU, TUC (CORD) Cenchrus myosuroides Root and rhizome: venereal No biological Nodata Kunth var. myosuroides diseases, diuretic, diaphoretic test Cadillo, cadillo alto. BAI, CAT, CHA, COR, COS, DFE, Ariza Espinar 2342 ERI, FOR, JUJ, LPA, LRI, MEN, (CORD) MIS, SAL, SDE, SFE, SJU, SLU, TUC Chloris elata Desv. Rhizome: anti-anorexia, refrigerant, No biological No data Hunziker 13361 (CORD) emmenagogue test BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, TUC Chusquea coleous Desv. Inflorescence: contraceptive No biological No data Caña colihue, colihue, CHU, NEU, RNE test culeu, quila KURTZIANA Boelcke 5386 (SI) Chusquea ramosissima Part not specified: to remove No biological No data Lindm. spines, hemostatic, antirheumatic, test Tacuarembó febrifuge, for feet edema and Biganzoli 968 (SI) conjunctivitis, to reduce weight MIS

BARBOZA, G.E.etal.MedicinalfloraofArgentina Cortaderia atacamensis Part not specified: febrifuge No biological No data (Phil.) Pilg. JUJ, LRI test Cortadera Arenas 1880 (SI) Cortaderia selloana Root: menstrual diseases, used in Aerial parts: No data (Schult. & Schult.f.) Asch. pregnancy and facilitate birth, post antimicrobial & Graebn. partum pains and diseases activity Cortadera, penacho de las Rhizome: hepatic, antinephritic pampas, plumacho, paja Leaf: capillary fragility tonic cortadera, cola de zorro. Part not specified: febrifuge, Hunziker 18649 (CORD) bequic, cholagogue BAI, CAT, CHA, CHU, COR, ERI, FOR, LPA, LRI, MEN, RNE, SAL, SFE, SJU, SLU, TUC Cortaderia speciosa (Ness Root + leaf: antifright No biological No data & Meyen) Stapf Part not specified: febrifuge, test Hunziker 1314 (CORD) bequic, cholagogue, capillar tonic CAT, JUJ, LRI, MEN, SAL, SJU Digitaria horizontalis Vegetative plant: contraceptive No biological No data Willd. Entire plant, infusion: for fertility test Cebadilla regulation Zuloaga 7287 (SI) Part not specified: abortifacient CHA, COS, FOR, JUJ, SAL Digitaria insularis (L.) Part not specified: antitussive No biological No data Fedde BAI, CAT, CHA, COR, COS, ERI, test Pasto bandera, pasto FOR, JUJ, LRI, MIS, SAL, SDE, cabezón, camalote, pasto SFE, SLU, TUC amargo, pasto camalote Hunziker 1116 (CORD) Eleusine tristachya (Lam.) Rhizome: antidiarrheal, No biological Dried inflorescence. Triglochinin: cyanoglucoside Lam. antidysenteric test Pata de gallo, pasto ruso BAI, CAT, CHA, COR, COS, DFE, Hunziker 13242 (CORD) ERI, FOR, JUJ, LPA, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC 67

Elionurus muticus Dried entire plant, infusion: remedy Aerial part + Essential oil. Geranial, neral, geranyl acetate 68 Tomo34(1-2):7-365.2009 (Spreng.) Kuntze when contaminated honey has been root: free Aerial part. Phenolic compounds Pasto amargo, paja amarga, ingested causing vomiting radical espartillo, aibe, colita Root: antidiarrheal, antidysenteric, scavenging peluda febrifuge, antitussive activity and Ariza Espinar 465 BAI, CAT, CHA, CHU, COR, COS, antioxidant ERI, FOR, JUJ, LPA, MEN, MIS, activity RNE, SAL, SFE, SLU, TUC Essential oil: potential analgesic and antibacterial action Eriochloa punctata (L.) Entire plant: general malaise, with No biological No data Desv. ex Ham. fever, chills and headache test Guaglianone et al. 269 BAI, CAT, CHA, COR, COS, DFE, (CORD) ERI, FOR, JUJ, MIS, SAL, SFE, SLU, TUC Festuca orthophylla Pilg. Plant: febrifuge No biological No data Ichu, iro, iru, irucho, ischu, JUJ, SAL, TUC test paja de puna Morrone 2555 (SI) Guadua angustifolia Rhizome: diuretic, laxative, No biological No data Kunth digestive test Tacuara, tacuaruzú, tacuara CHA, COS, ERI, FOR, MIS, SFE, guazú, tacuara grande TUC Parodi 5543 (SI) Guadua chacoënsis (Rojas Rhizome: urinary antiseptic, No biological No data Acosta) Londoño & P.M. laxative, analgesic test Peterson CHA, COS, MIS, TUC

Krapovickas 28759 (SI) KURTZIANA Gymnopogon spicatus Rhizome: diuretic, nephritic, No biological No data (Spreng.) Kuntze antiphlogistic test Pasto araña Rhizome + aerial stem: Ariza Espinar 2830 abortifacient (CORD) CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Gynerium sagittatum Plant: in snakebite treatments No biological Root. (2R,3R)-2,3-trans-7,4'-dimethoxydihydroflavonol, (Aubl.) P. Beauv. Leaf buds: boils, wounds, skin test (2R,3S,4S)-2,3-trans-3,4-cis-7,4'-dimethoxy-3,4-flavandiol, Tacuatí fungus 6-hydroxy-7,4'-dimethoxyflavone, 6,7,4'-trimethoxyflavone: Martínez Crovetto 3408 CHA, COS, FOR, JUJ, MIS, SAL flavonoids; ferreirin, dihydrocajanin, dalbergioidin, (CORD) dihydrobiochanin A, : Heteropogon contortus Part not specified, infusion: for No biological No data (L.) P. Beauv. ex Roem . & asthma test Schult. Root: antivenin Hunziker 9116 (CORD) CHA, COR, COS, FOR, JUJ, MIS, SAL, SLU, TUC Imperata brasiliensis Root + rhizome: diuretic, No biological No data Trin. diaphoretic, teething pain test Sapé, yajapé, yahapé, capií Dried leaf, decoction: used for yoa diabetes, against gonorrhoea and Anton et al. 67 (CORD) leucorrhoea BAI, CHA, COR, COS, FOR, JUJ, LPA, MIS, SAL, SFE, TUC Lolium multiflorum Lam. Part not specified: anti-diarrhea, No biological Plant. Proteins, lignin, minerals (Ca, Na, K, P, Mg, Zn, Fe, Ballico, cola de zorro, emmenagogue test Cu, Mn) pasto ray, raigrás, ray grass, BAI, CHU, COR, COS, ERI, JUJ, ray grass criollo, vallico LPA, MEN, NEU, RNE, SCR, SFE, Nicora 1479 (SI) SLU, TDF, TUC, Panicum trichanthum Entire plant: general malaise, with No biological No data Nees fever, chills and headache test Zuloaga et al. 2217 (SI) CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE Paspalum distichum L. Root: hepatic, diuretic, venereal Aerial parts: No data Gramilla blanca, chépica, diseases, abortifacient toxic effect gramón, gramilla dulce, Rhizome: refrigerant, digestive, pata de gallina febrifuge Hunziker 13263 (CORD) BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, RNE, SAL, SDE, SFE, SJU, TUC 69

Paspalum notatum Flüggé Root: venereal diseases, diuretic No biological No data 70 Tomo34(1-2):7-365.2009 var. notatum BAI, CAT, CHA, COR, COS, DFE, test Pasto horqueta, gramilla ERI, FOR, JUJ, LPA, MEN, MIS, blanca, SAL, SDE, SFE, SLU, TUC Paspalum notatum var. latiflorum Döll Hosseus 1140 (CORD) Paspalum vaginatum Sw. Root: diuretic No biological No data Gramilla blanca, gramilla, BAI, CAT, CHA, COR, COS, DFE, test chépica ERI, FOR, JUJ, LPA, MEN, MIS, Hunziker et al. 21250 RNE, SAL, SFE, SJU, TUC (CORD) Rhipidocladum Root: to induce abortion, No biological No data racemiflorum (Steud.) contraceptive test McClure SAL, TUC Caña hueca Guaglianone 2730 (SI) Schizachyrium Root: anti-asthmatic, refrigerant, No biological No data condensatum (Kunth) diuretic, febrifuge test Nees BAI, CAT, CHA, COR, COS, ERI, Pasto colorado, paja FOR, JUJ, LPA, MEN, MIS, SAL, colorada, cola de liebre, SDE, SFE, SLU, TUC cola de zorro, té pampa Cantero et al. s.n. (RIOC 4954) Schizachyrium Root: diuretic, febrifuge No biological No data microstachyum (Desv. ex COS, ERI, MIS test Ham.) Roseng., B.R. Arrill. & Izag.

Pasto colorado KURTZIANA Chiapella 1927 (CORD) Sorghastrum pellitum Root: antidysenteric, venereal No biological No data (Hack.) Parodi diseases, diuretic, diaphoretic test Pasto de vaca, paja BAI, CHA, COR, COS, ERI, JUJ, colorada. LPA, MEN, MIS, SAL, SFE, SLU, Hunziker 9591 (CORD) TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Sporobolus indicus (L.) R. Entire plant, infusion: for fertility Dried aerial No data Br. regulation, contraceptive parts: diuretic Nido de perdiz, inambú Part not specified: abortifacient activity rogá, in ambú rayti, capii- BAI, CAT, CHA, COR, COS, DFE, yy, cabayú ruguay ERI, FOR, JUJ, LPA, MIS, SAL, Cantero et al. s.n. (RIOC SFE, SLU, TUC 4616) Sporobolus rigens (Trin.) Part not specified: diuretic No biological No data E. Desv. var. rigens BAI, CAT, CHU, COR, JUJ, LPA, test Junquillo, unquillo, unco, MEN, NEU, RNE, SAL, SFE, SJU, carrizo, pasqueta, paja de SLU, TUC médano Hunziker 10501 (CORD) Stenotaphrum Rhizome: diuretic, refrigerant Dried leaf: Dried aerial parts. Orientin-2''-O-glucoside: flavone; secundatum (Walter) Fresh leaf, decoction: to treat radical orientin-2''-O-β-D-xyloside: flavone glycosides Kuntze urinary scavenging Gramillón, gramilla, pelote, BAI, COR, ERI, SFE, TUC effect pasto colchón Cantero et al. s.n. (RIOC 748) PONTEDERIACEAE Eichhornia azurea (Sw.) Root and leaf: antidysenteric, Leaf: anti- Leaf. Flavonoids Kunth venereal diseases, astringent inflammatory Camalote Flowers: cordial activity Arbo 7881 (CTES) BAI, CHA, COR, COS, ERI, FOR, MIS, SFE Eichhornia crassipes Entire plant: antineoplasic, diuretic, Leaf, stem + Dried entire plant. Eichhornia dimer 4, eichhornia dimer 5, (Mart.) Solms headache, antidiarrheal root: eichhornia dimer 6: polycyclics Camalote, aguapey, yuapé, Root and leaf: antidysenteric antibacterial Fresh leaf. Alanine, phenyl alanine, arginine camalote ombligo, jacinto venereal diseases, astringent activity Leaf + root: 8-phenylphenalenones de agua, lirio de agua Petiole: hepatic Leaf: Flower: Delphinidin-3-gentiobiosyl ( 7-glucosyl) Hunziker 16319 (CORD) Flowers: cordial, analeptic, antiparasitic malonate aphrodisiac, sedative; antidysenteric, activity Root. Putrescine, spermidine: alkaloids; linoleic acid: lipid febrifuge, diuretic

BAI, CHA, COS, ERI, FOR, JUJ, 71 LRI, MIS, SAL, SFE, TUC

72

Pontederia cordata L. Entire plant, infusion: for No biological Dried entire plant. α-amyrin, campesterol: triterpenes; Tomo34(1-2):7-365.2009 Camalote prevention of pregnancy test sterols Cocucci 3160 (CORD) Part not specified: venereal diseases, antidysenteric BAI, CHA, COS, DFE, ERI, FOR, MEN, MIS, SFE SMILACACEAE Smilax campestris Griseb. Root: antisyphilitic, diaphoretic, Rhizome: Leaf. Kaempferol, kaempferol-3-0-rutinoside, quercetin, Zarzaparrilla, zarzaparrilla diuretic, for infections, hernia and antioxidant quercetin-3-0-glucoside, quercetin-3-0- negra, zarzaparrilla blanca, prolapse, menstrual diseases activity rhamnogalactoglucoside, , isorhamnetin-3-0- japicanga Rhizome: antisyphilitic, diuretic, Plant: rutinoside, rutin: flavonols Martínez 458 (CORD) sudorific, aperitive, refrigerant, mutagenic, Rhizome. Quercetin, 3-glucoside, 3-rutinoside, , laxative antioxidant, propelargonidin: flavonoids Aerial parts: anti-inflammatory, anti- antidiarrheal, and for wounds inflammatory, Leaf: antisyphilitic, antirheumatic antimicrobial, Flower: vaginal fungus antitumoral and BAI, CHA, COR, COS, ERI, FOR, hepatoprotective JUJ, MIS, SAL, SDE, SFE, TUC activity TYPHACEAE Typha angustifolia L. Entire plant: stimulant, aphrodisiac Dried entire Dried entire plant. Iso : flavonol Totora Rhizome: diuretic plant: Dried pollen. Daucosterol: steroid; kaempferol-3-0- Forcone 580 (CORD) Leaf: antidysenteric, hemostatic anticoagulant and rhamnosyl-glucoside: flavonol CHA, RNE antimycobacterial activity Pollen: immunosuppres sive activity Typha dominguensis Pers. Rhizome: nefritic No biological No data

Totora Leaf and rhizome: astringent, test KURTZIANA Subils 737 (CORD) stomachic, abluent, antidiarrheal , antitussive, venereal diseases BAI, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, RNE, SAL, SFE, SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Typha latifolia L. Rhizome: anti-ulcer Stem: Stem. Flavonoids, alkaloids, sugars Totora, espadaña Leaf: diuretic, laxative, antimicrobial, Part not specified. Typhasterol: steroid Subils 1174 bis (CORD) antidysenteric, venereal diseases antioxidant, and BAI, COS, ERI, LPA, MIS, SFE, cytotoxic SJU activity Typha subulata Crespo & Leaf: diuretic, sudorific No biological No data R. L. Pérez- Mor. BAI, CHU, COR, COS, ERI, JUJ, test Totora LPA, MEN, RNE, SJU, SLU Hunziker 18682 (CORD) XYRIDACEAE Xyris jupicai Rich. Juice: to relieve the pruritis No biological No data Jupicai CHA, COS, ERI, FOR, MIS test Xyris jupicai var. major (Mart.) L. B. Sm. & Downs Pedersen 9079 (CORD) 73

ANGIOSPERMAE-DICOTYLEDONEAE 74 Tomo34(1-2):7-365.2009 TAXA ETHNOMEDICAL BIOLOGICAL ACTIVITIES CHEMICAL DATA (Family, Latin Name, INFORMATION/ Vernacular Names, DISTRIBUTION Synonyms, Exiccatum) ACANTHACEAE Justicia comata (L.) Lam . Part not specified: ophtalmic No biological test No data Kurtz 1546 (CORD) CHA, COS, FOR, JUJ, MIS, SAL, SFE Justicia pectoralis Jacq. Leaf : sedative, pectoral Aerial plant: antinociceptive, Aerial plant. Coumarin, umbelliferone, Arenas 2283 (CORD) FOR anti-inflammatory, sedative, and betain, flavonoids, saponins, bronchodilatador activity aminoacids Dried leaf: anti-inflammatory activity Ruellia ciliatiflora Hook.. Part not specified: emetic No biological test No data Hunziker 7641 (CORD) CAT, CHA, COR, COS, FOR, JUJ, LRI, SAL, SDE, TUC Ruellia hygrophila Mart. Root: anti-inflammatory, No biological test No data Reventador stimulant, antidiarrheal; decoction: Fortunato 6734 (BAB) for swellings and stomache-ache Leaf: antidiarrheal CHA, COS, FOR, MIS, SAL, SDE, SFE Ruellia simplex Wright Leaf: antidiarrheal No biological test No data Zuloaga 3179 (SI) CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC ACHATOCARPACEAE Achatocarpus praecox Root: cicatrizant No biological test No data Griseb. var. praecox CHA, FOR, JUJ, MIS, SAL, SFE, Palo tinta, tala negro, urajú, TUC KURTZIANA palo matico, palo mataco Hunziker 17508 (CORD) Achatocarpus praecox var. Part not specified: odontalgic and No biological test No data bicornutus (Schinz & for gingivitis Autran) Botta COS, ERI, FOR, MIS, SAL Burkart 21187 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina ADOXACEAE Sambucus australis Cham. Bark and root: cathartic, laxative, Dried flowers: mutagenic No data & Schltdl. diuretic, hydrogogue activity Sauco, saúco Leaf: anti-inflammatory, cicatrizant, Hunziker 9961 (CORD) antihemorrhoidal, febrifuge. Flowers: digestive, diuretic, diaphoretic, vulnerary, for insolation and burns; infusion: antithermic Fruits: depurative, antidiarrheal, pectoral BAI, CHA, COR, COS, ERI, FOR, MIS, SFE Sambucus nigra subsp. Plant: diuretic Part not specified: Aerial parts. 3’,4’-dihydroxylated in B peruviana (Kunth) R. Bolli Bark: cathartic antimicrobial activity ring flavonoids Saúco, mololo, saúco Leaf: stimulant, anti-inflammatory serrrano, sauco del noroeste, Flower + leaf: neonatal and kiola paediatrics care Morrone 3806 (SI) Flower: diaphoretic, for infections, used in pregnancy and facilitate birth, post-partum pains CAT, JUJ, NEU, SAL, TUC AMARANTHACEAE Alternanthera ficoidea (L.) Entire plant: antitussive No biological test Leaf. : benzenoid Sm. Dried leaf: for snakebite Entire plant. Alkaloids present Vanni 3603 (CTES) MIS Alternanthera Dried entire plant, decoction: No biological test Dried aerial parts. α-Spinasterol: paronychioides A. St.-Hil. antidiarrheal, to treat respiratory steroid subsp. paronychoides disorders Yerba de pollo Root: diuretic, depurative Cantero et al. s.n. (RIOC 701) BAI, CHA, COS, ERI, SFE Alternanthera Root and leaf: diuretic, Dried aerial part: antitumor Dried leaf + stem. Alternanthin: favone; philoxeroides (Mart.) Griseb. depurative, digestive, hepatic and antiviral (HIV and anti- glutamic acid, aspartic acid: amino acids Yerba d e pollo, gu ambarusa, Dried leaf + stem, infusion: for viral Hantaan) activity; reverse Aerial part. phaeophytin a, pheophytin a', raíz colorada, lagunilla diseases, hepatitis, epidemic parotitis, transcriptase inhibition oleanoic acid, β-sitosterol, 3β- Cantero et al. s.n. (RIOC hemorrhagic fever, and influenza hydroxystigmast-5-en-7-one, α-spinasterol, 1570) BAI, CHA, COS, ERI, FOR, JUJ, 24-methylenecycloartanol, cycloeucalenol, SAL, SDE, SFE, SJU, TUC phytol, alternanthin B, N-trans-feruloyl- 75 3,5-dimethoxytyramine

Alternanthera pungens Dried aerial parts, infusion: for Dried entire plant: diuretic Whole plant. Choline 76 Tomo34(1-2):7-365.2009 Kunth hepatic problems and gastritis; activity; intestinal motility Flowers. Azulene, α-curcumene: Yerba d el pollo, yerba del carmintive; decoction: stimulation, smooth muscle sesquiterpenes; bornyl acetate, α- pajarito, quisca-yuyo, pasto antidiarrheal and to treat urinary stimulant activity borneol, camphene, camphor, 1-8- del pollo, aspa quiska and respiratory disorders Dried fruit: laxative effect cineol, α-terpineol: monoterpenes Hunziker 14926 (CORD) Root + aerial parts: diuretic, Dried fruit. Oleanolic acid: triterpene; depurative, to relieve the rutin: flavonol stomachache BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Amaranthus blitum L. Leaf: laxative, emollient Dried leaf + stem: nematocidal Dried leaf. : flavonol; Ataco Root + seed, infusion: antifertility activity vitamin K Hunziker 24939 (CORD) agent Seed oil. β-amyrin, lupeol: triterpenes; BAI, CHA, COS, FOR, SAL, SFE, linoleic acid, myristic acid, oleic acid, TUC palmitic acid: lipids

Amaranthus deflexus L. Root and stem: diuretic, laxative, No biological test Dried aerial parts. Hyperoside, jacein Yuyo colorado emollient BAI, CHU, COR, ERI, centaurein, -3-O-β-D- Hunziker 18677 (CORD) LPA, MEN, NEU, RNE, SJU glucoside: flavonol Amaranthus hybridus L. Aerial parts: laxative, diuretic Fruit: antioxidant activity Dried aerial parts. Afrormosin-7-O-β- subsp. hybridus Leaf + seed: post partum pains D-glucoside: isoflavone Yuyo colorado, ataco, aroma and diseases Fruit. Caffeic acid, ferulic acid, p- Amaranthus qu itensis Kun th (sub nom. A. quitensis) coumaric acid, p-hydroxybenzoic acid Hunziker 10934 (CORD) BAI, CAT, COR, COS, ERI, FOR, and protocatechuic acid JUJ, LRI, MEN, MIS, NEU, SAL, Dried seed. Arachidic acid: lipid SDE, SFE, SJU, TUC Seed oil. 5-dehydro avenasterol: steroid Amaranthus lividus L. Leaf: laxative, emollient No biological test Leaf, stem + root. Alkaloids, Lanfranchi 522 (LP) BAI, COS, ERI glycosides and/or carbohydrates,

flavonoids, sterols, tannins, sulphates KURTZIANA Plant. Aspartic acid, threonime, serine, glutamic acid, proline, glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, histidine, lysine, arginine: aminoacids Dried seed. Agglutinin: protein.

BARBOZA, G.E.etal.MedicinalfloraofArgentina Amaranthus muricatus Root: digestive Aerial part: diuretic effect Dried aerial parts. Centaurein, (Moq.) Hieron. Aerial parts: antilithic, diuretic, hyperoside: flavonol; rhein: quinone Yuyo colorado, ataco, yerba laxative meona, mea mea BAI, CHA, COR, COS, FOR, JUJ, Hunziker 20249 (CORD) LRI, MEN, SAL, SFE, SJU, SLU, TUC Amaranthus spinosus L. Entire plant, infusion: febrifuge, Entire plant: antispasmodic Dried aerial parts. Leucine: protein; Ataco espinudo for eczema, emmenagogue and activity nicotiflorin: flavonol Hunziker 2774 (CORD) galactagogue Dried aerial parts: antifungal Dried leaf. Alanine, phenyl alanine; Root, infusion: to treat activity; UV absorbent effect oxalate oxidase, arginine: proteins menorrhagia, for nervous tension regulation, stomach ulcers, and venereal diseases Dried rhizome, infusion: for liver disease Leaf: emollient, anti-inflammatory CHA, COS, JUJ, LPA, MIS, SAL Amaranthus viridis L. Aerial parts: emollient, laxative; Dried entire plant: anti- Dried aerial parts. Afrormosin-7-O-β- Yuyo colorado, bledillo for snakebite inflammatory and antipyretic D-glucoside, -7-O-galactoside: Hunziker 1800 (CORD) Entire plant, infusion: activity isoflavone; astragalin-7-O-rhamnoside, galactagogue; Leaf: antiviral and fungal flavone, 3-4'-dihydroxy, 7-O-β-D- decoction: vermifuge and anti- stimulant glucoside, quercetin, rutin: flavonols; inflammatory cholesterol, 22-dehydro, 24-ethyl, Root, juice: febrifuge cholesterol, 24-ethyl: steroids Leaf, powder: anti-inflammatory Plant. Aspartic acid, threonime, serine, BAI, CHA, COS, ERI, FOR, JUJ, glutamic acid, proline, glycine, alanine, LRI, MIS, SAL, SDE, SFE, SJU valine, leucine, isoleucine, phenylalanine, tyrosine, histidine, lysine, arginine: aminoacids Fresh inflorescence. Flavonoids present Amaranthus vulgatissimus Part not specified: diuretic No biological test No data Speg. BAI, CAT, CHU, COR, JUJ, Ataco silvestre MEN, SFE, SJU

Botta 716 (SI) 7

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Chamissoa altissima Leaf: for weakness No biological test No data Tomo34(1-2):7-365.2009 (Jacq.) Kunth Root: diuretic, sedative Pabellón del rey CHA, COS, FOR, JUJ, MIS, SAL, Cabrera 29232 (SI) TUC Gomphrena celosioides Entire plant: hypotensive, Dried aerial parts: antimalarial, Entire plant. Ecdysone: steroid Mart. var. celosioides antirheumatic, carminative; diuretic and antimicrobial Peludilla, yerba del chancho infusion: for fertility regulation; activity Ariza Espinar 1236 (CORD) decoction: for malaria Dried leaf: antifungal activity Dried leaf, infusion: contraceptive BAI, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Gomphrena mendocina Part not specified: laxative No biological test No data (Phil.) R. E. Fr. CHU, LRI, MEN, RNE, SJU Chiapella 1910 (CORD) Gomphrena perennis L. var. Flowers: febrifuge, antirheumatic, Dried entire plant: antitumor Dried entire plant. Ecdysone: perennis antidiarrheal, stomachic and antimycobacterial activity steroid Siempreviva Dried root, infusion: to prevent Part not specified: smooth Hunziker 16781 (CORD) menstrual hemorrhage muscle relaxant activity BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, TUC Gomphrena pulchella Flowers: febrifuge, antirheumatic, Dried entire plant: antibacterial No data subsp. rosea (Griseb.) antidiarrheal, stomachic and antimycobacterial activity Pedersen Part not specified: emollient, Siempreviva, siempreviva del purgative, diuretic campo COR, SLU Hunziker 16459 (CORD) Guilleminea densa (Willd. Aerial parts: diuretic, laxative, No biological test No data ex Roem.& Schult.) Moq. stomachic, hepatic, to alleviate Hierba del pollo, yerba de insects bite KURTZIANA pollo CAT, COR, COS, DFE, FOR, JUJ, Hunziker 14810 (CORD) SAL, SFE, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Hebanthe eriantha (Poir.) Root: for cancer and leukemia; Root: anti-cancerous activity, Root. Amino acids, iron, magnesium, Pedersen general tonic; as an energy, antisickling effect and zinc, vitamins A, B1, B2, E, K, Suma, para todo, Brazilian rejuvenating, and sexual tonic; and rehydration effect of sickled pantothenic acid, saponins, pfaffic ginseng as a general cure-all for many cells, analgesic and anti- acids, glycosides, nortriterpenes, Pfaffia paniculata (Mart.) types of illnesses; aphrodisiac, inflammatory activity; increases allantoin, β-ecdysterone, β-sitosterol, Kuntze calming agent, and to treat ulcers sexual performance and function daucosterol, germanium, pfaffosides A- Montes 15444 (SI) (sub P. paniculata) F, polypodine B, silica, stigmasterol, MIS stigmasterol-3-0-β-d-glucoside Iresine diffusa Humb. & Aerial part: colds, pain in bowels, No biological test Dried aerial parts. Trigonelline: Bonpl. ex Willd. var diffusa colic, inflammation of the ovaries alkaloid; glycine-betaine: alkaloid- Peludilla, paja blanca, Leaf + flowers: emmenagogue misc; iresin, 3β,14-dihydroxy-Delta(7, sangrinaria BAI, CAT, CHA, COR, COS, 8)-drimen-11,12-acetonide, 3-β,7-β,14- Ariza Espinar 184 (CORD) DFE, ERI, FOR, JUJ, LRI, MIS, trihidroxy-Delta(8, 9)-drimen-11,12- SAL, SDE, SFE, SJU, SLU, TUC olide, 3-β,7-α,14-trihydroxy-Delta(8, 9)-drimen-11,12-olide: terpenes Pfaffia tuberosa (Spreng.) Rhizome: refrigerant, anti-ulcer No biological test No data Hicken f. tuberosa Root: to increase fertility Batatilla BAI, CHA, COS, ERI, FOR, MIS, Arbo 8655 (CTES) SFE ANACARDIACEAE Astronium balansae Engl. Leaf: purgative, analgesic, Bark + branches: bactericidal Wood + bark. Urunday, urunday crespo, febrifuge, in treatment of activity urunday pichaí, urunday insolation, to treat cephalalgia rubio, urunday overo CHA, COS, FOR, MIS, SFE Kurtz 1570 (CORD) Astronium urundeuva Dried bark, decoction: for Dried stem bark: analgesic, Dried heart wood. Matosine: urunde (Allemão) Engl. var. cervicitis and gastric ulcers, anti- antiulcer, analgesic, anti- B, uvinurundeuvin B, sakuranetin: urundeuva inflammatory agent inflammatory, and antioxidant flavonoids. Urundel, urunday del Dried branches: for bronchitis activity, intestinal absorption Essential oil leaf + fine branches. δ-3- noroeste, urunday-mí and ovarian inflammation inhibition carene Fortunato 6132 (BAB) CHA, JUJ, SAL Leaf: antifungal activity Fresh fruit: dermatitis producing effect

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Lithraea molleoides (Vell.) Leaf: anti-arthritic, anti- Leaf: antiviral, antimicrobial, Dried aerial parts. Methyl gallate, Tomo34(1-2):7-365.2009 Engl. inflammatory, hemostatic, diuretic nematicidal, antihemolytic and protocatechiuc acid; Molle de beber, molle, molle Twigs, decoction: for treatment of cytotoxic activity; (Z,Z)-5-(trideca-4,7-dienyl)resorcinol, de Córdoba, aruera, chichita respiratory and digestive diseases, immunomodulating properties; (Z,Z,Z)-5-(trideca-4,7,10- colorada for coughs and bronchitis; cell proliferation inhibition trienyl)resorcinol, (Z,Z,E)-5-(trideca- Ariza Espinar 813 (CORD) hemostatic, diuretic, tonic, 4,7,10-trienyl)resorcinol, and (Z)-5- refreshing (trideca-4-enyl) resorcinol: alkylene Fruit, decoction: for treatment of resorcinols eruptive diseases Dried leaf: 1-3-dihydroxy-5-(trideca-4'- CAT, CHA, COR, COS, ERI, 7'-dienyl) benzene: benzenoid FOR, JUJ, LRI, MIS, SAL, SFE, SJU, SLU, TUC Schinopsis balansae Engl. Cortex: anti-inflammatory, Dried bark: gonadotropin and Dried bark. Quebracho colorado, quebra- cicatrizant, antiseptic antibacterial activity, anti- cho colorado chaqueño, Wood: astringent pregnant mare-serum quebracho santafesino Fresh sap: to remove moles Martínez 244 (CORD) CHA, COS, ERI, FOR, SDE, SFE Schinopsis lorentzii (Griseb.) Leaf: cicatrizant, to relieves No biological test Heart wood. Condensed tannin Engl. bruises Quebracho colorado, (sub nom. Schinopsis quebracho- quebracho colorado colorado) santiagueño Bark: anti-asthmatic Martínez 374 (CORD) CHA, COR, FOR, JUJ, SAL, SDE, SFE, TUC Schinus areira L. Plant: sneezing and asthma-like Leaf: anti-inflammatory activity; Dried fruit. Agathisflavone, Aguaribay, pimentero, bálsa- reactions, abortifacient wound healing action amentoflavone, husflavanone: mo, gual eguay, curanguay, Branches: for cramps, join pains, Leaf + fruit: repellent effect on flavonoids árbol de la pimienta, molle pains in the bones Triatoma infestants Essential oil. Limonene, α- Cantero et al. s.n. (RIOC Leaf: emmenagogue, laxative, Aerial parts essential oil: phellandrene, sabinene, camphene

5295) antirheumatic, antiseptic, fumigant and repellent activity Aerial parts essential oil. Camphene, KURTZIANA purgative, anti-inflammatory, against head lice p-cymene, limonene, α-pinene, β- abortive, cicatrizant, topic pinene: monoterpene hydrocarbon; δ- disinfectant, to treat anorexia, lack cadinene, γ-cadinene, β-caryophyllene: of appetite, anxiety and irritability sesquiterpene hydrocarbon; τ-cadinol: oxygenated sesquiterpene

Schinus areira L. Dried bark + leaf, infusion: for BARBOZA, G.E.etal.MedicinalfloraofArgentina (continuation) foot edema Trunk exudate: causes vesication and severe itching Resinous exhalation: causes skin eruptions CAT, COR, JUJ, LPA, LRI, MIS, SAL, SJU, SLU, TUC Schinus bumelioides I. M. Parts not specified: febrifuge, No biological test No data Johnst. against the influenza, stomachic, Molle, molle negro, molle abortifacient espinoso CAT, COR, ERI, JUJ, LRI, MEN, Hunziker 10830 (CORD) SAL, SDE, SFE, SJU, SLU, TUC Schinus fasciculatus var. Aerial parts: cicatrizant, No biological test No data arenicola (Hauman) disinfectant F.A.Barkley BAI, CAT, CHA, COR, COS, Molle, molle pispito DFE, ERI, FOR, JUJ, LPA, LRI, Fortunato 6279 (BAB) MEN, RNE, SAL, SDE, SFE, SJU, SLU, TUC Schinus fasciculatus Leaf: antitussive, antirheumatic, Aerial parts: antibacterial Essential oil. Limonene, β- (Griseb.) I.M.Johnst. var. purgative, analgesic, vulnerary, activity phellandrene, α-phellandrene fasciculatus antidysenteric; decoction: Moradillo, molle, molle analgesic, antitussive fragante, molle santiagueño, (sub nom. S. fasciculatus) trementina, molle Pippi, CAT, CHA, COR, COS, ERI, moradilla, molle negro FOR, JUJ, LPA, MEN, SAL, SDE, Hunziker 14955 (CORD) SFE, SJU, TUC Schinus johnstonii F. A. Part not specified: medicinal No biological test No data Barkley BAI, CHU, MEN, NEU, RNE, Molle SJU, SLU Chiapella s.n. (CORD) Schinus longifolius (Lindl.) Aerial parts: for hair care No biological test Essential oil. α-pinene, β-pinene, α- Speg. var. longifolius (dandruff and seborrhea) phellandrene Molle, incienso, molle Leaf: expectorant, laxative

rastrero, incienso, molle BAI, CHA, COR, COS, ERI, FOR, 81 negro, moradillo MIS, SFE, SLU Cerana 1911 (CORD)

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Schinus meyeri F. A. Medicinal No biological test No data Tomo34(1-2):7-365.2009 Barkley SAL Chirimolle Hilgert 1482 (CORD) Schinus molle L. Entire plant, decoction: antipyretic, Dried entire plant: Entire plant. α-amyrin: triterpene Aguaribay, árbol de la anti-inflammatory, emmenagogue; antiyeast activity Leaf essential oil. Croweacin: pimienta, curanguay, chichita antifungal, antibacterial, Aerial parts: aldose reductase phenylpropanoid; limonene, sauce, molle, pimentero, antirheumathic, anti-conjunctivitis, to inhibition, inhibitory effect on phellandrene, , cis-men-2-en- chichita péndula, falso treat skin affections, ulcer, urinary histamine and serotonin, 1-ol, trans-piperitol: terpenes; laccase: pimentero, anacahuita tract diseases and respiratory diseases giardicidal, analgesic, antibacterial, glycoprotein Hunziker 649 (CORD) Bark, infusion: purgative, and cytotoxic activity Leaf. Isoquercitrin 6’’-O-p- stimulant Leaf: antiviral, analgesic, hydroxybenzoate, 2’’-O-α-l- Leaf, decoction: analgesic, hypotensive, antioxidant, and rhamnopyranosyl-hyperin 6’’-O-gallate: antitussive, antidepressant, anti- cytotoxic activity; acylated quercetin glycosides; gallic inflammatory, hypotensive, antidepressant-like effect acid, methyl gallate, chlorogenic acid, neonatal and paediatrics care, for Leaf essential oil: antibacterial, 2’’-α-l-rhamnopyranosyl-hyperin, infections, hernia and prolapse antifungal, and antiseptic quercetin 3-O-β-d-neohesperidoside, Leaf and fruits: emmenagogue, activity; disminution of the , quercetin, rutin, quercetin anti-inflammatory, antiseptic arterial blood pressure 3-O-β-d-galacturonopyranoside, Fruit: diuretic, antirheumathic, Fruit: hypotensive and anti- isoquercitrin, hyperin; isoquercitrin 6’’- anti-inflammatory, and for inflammatory activity, uterine gallate, hyperin 6’’-O-gallate, (+)- amenorrhea and dysmenorrhea stimulant effect : polyphenolics Essential oil: for venereal diseases Fruit essential oil. α-bergamont-trans, Oleoresin, infusion: antirheumatic, α-cadinol, γ-cadinene, bourbonene: cicatrizant, purgative sesquiterpenes; α and β-phellandrene, COS, ERI, MIS, SFE β-spathulene, D-limonene silvestrene, α-pinene, β-pinene, carvacrol, myrcene, camphene, o-ethyl-phenol, p-cymene, p-cymol, γ-cubebene, α- and γ- muurolene Fruit. Isomasticadienonic-, KURTZIANA isomasticadienonalic- masticadienonic-, 3-epi-isomasticadienolic acids: triterpenoid acids; chamaejasmin: flavonoid

BARBOZA, G.E.etal.MedicinalfloraofArgentina Schinus odonellii F. A. Barkley Aerial parts: antirheumatic, anti- No biological test No data Molle arthritic Ambrosetti 1423 (CORD) MEN, NEU, RNE Schinus patagonicus (Phil.) Part not specified: antirheumatic Aerial parts: antimicrobial Aerial parts. α-phellandrene, 4- I. M. Johnst. ex Cabrera Resin: for oral hygienic activity terpinenol Laura CHU, MEN, NEU, RNE Cocucci 1401 (CORD) Schinus polygamus (Cav.) Aerial parts: balsamic, Leaf + stem: cytotoxic activity, Dried leaf. Hyperoside, kaempferol, Cabrera antirheumatic, icteric, antipyretic, anti-inflammatory, quercetin, quercetin-3-O-galactoside: Molle, molle incienso, molle galactagogue, ophtalmic, purgant, and analgesic activity flavonoids; β-sitosterol, shikimic acid negro, trementina, huingán vulnerary, anti-arthritic, and for Leaf + fruit essential oil: Leaf essential oil. α-thujene, α-pinene, β- Kiesling 10093 (SI) cleansing of wounds and for antimicrobial activity pinene, β-myrcene, p-cymene, limonene, antifertility treatment Resin: larvicidal activity 1-octanol, linalool, endo-fenchol, trans- Bark: to treat arthritic and feet pains pinocarveol, borneol, terpinen-4-ol, α- Latex bark: plaster for muscles terpineol, myrtenol, geraniol, 1-decanol, β- and tendons pains, dislocations, cubebene, trans-caryophyllene, α- fractures and irritation of the skin humulene, aromadendrene, 1-dodecanol, Resin: for chronic bronchitis epibicyclosesquiphellandrene, α- Part not specified: emmenagogue muurolene, γ-cadinene, δ-cadinene, MEN, SJU elemol, spathulenol, selina-3,11-dien-6-α- ol, epoxi-alloaromadendrene, α-cadinol Fruit essential oil: α-thujene, α-pinene, camphene, β-pinene, p-cymene, limonene, 1-octanol, linalool, endo-fenchol, trans- pinocarveol, camphor, borneol, terpinen-4- ol, α-terpineol, myrtenol, 1-decanol, bornyl-acetate, α-cubebene, α-copaene, trans-caryophyllene, α-humulene, 1- dodecanol, γ-cadinene, δ-cadinene, epibicyclosesquiphellandrene, α- muurolene, elemol, viridiflorol, selina- 3,11-dien-6-α-ol, muurolol, longifoliol

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Schinus weinmannifolius Aerial parts: antitussive, anti- No biological test No data Tomo34(1-2):7-365.2009 Engl. ashmatic, disinfectant, Molle´i, arue’i contraceptive Quiroga 7680 (LIL) COS, MIS ANNONACEAE Annona nutans (R. E. Fr.) R. Parts not specified: anticatarrhal Dried seed: anticrustacean Dried root bark. Chatenaytrienin 1, E. Fr. CHA, FOR, SAL activity chatenaytrienin 2, chatenaytrienin 3, Araticú chatenaytrienin 4: misc lactones Saravia Toledo 11490 (CORD) Rollinia emarginata Schldtl. Leaf: anti-inflammatory, against Dried stem bark: Dried stem bark. Liriodenine, (+)- Arachichú, araticú, aratigú, toothache antileishmaniasis activity reticuline, (-)anonaine, (-)-asimilobine: yerba mora CHA, COS, ERI, FOR, MIS, SAL, isoquinoline alkaloids Hunziker 6634 (CORD) SFE Rollinia salicifolia Schltdl. Bark: astringent Aerial part: antitumor activity No data Araticú mí COS, FOR, MIS Deginani 1579 (SI) Xylopia brasiliensis Spreng. Leaf: diuretic, diaphoretic, Essential oil: anti-trypanosomal Dried leaf. Ent Kaur-16-en-19-oic acid, Curuvú ihví laxative, expectorant and antispasmodic activity xylopic acid: diterpene Hatschbach 33666 (LP) Seed: carminative, purgative Essential oil. α-pinene, β-pinene, MIS camphene, limonene, caryophyllene, cadinene; kaurenoic acid: diterpene; Green fruit. 15-oxo Kaur-16-en-19-oic acid methyl ester: diterpene; spathulenol: sesquiterpene Fruit. Piperine: alkaloid Part not specified. 9- methoxyliriodenine: noraporphine alkaloid APIACEAE Apium panul (Bertero ex Part not specified: cephalalgic, No biological test No data KURTZIANA DC.) Reiche anti-diaphoretic, astringent, Panul depurative Kurtz 5767 (CORD) MEN, NEU, SJU, TUC

Apium prostratum Labill. Root + leaf: depurative, Dried aerial parts: β- Fresh leaf + stem. Bergapten, iso BARBOZA, G.E.etal.MedicinalfloraofArgentina Apio silvestre antirheumatic glucuronidase inhibition, pimpinellin, xanthotoxin: coumarins; Apium australe Thouars (sub nom. A. australe) anticrustacean activity myristicin: phenylpropanoid Cabrera 6323 (LP) BAI, CHU, MEN, SCR, TDF Leaf + stem: antitumor and cytotoxic activity Dried part not specified: β- glucuronidase and xanthine oxidase inhibition; DNA binding effect Apium sellowianum H. Wolff. Entire plant, infusion: Dried seed: insecticide activity Seed. Oleic acid, petroselinic acid: Apio cimarrón, apio silvestre emmenagogue Dried part not specified: lipids Kurtz 7767 (CORD) Dried leaf, decoction: to treat feeding deterrent urinary and respiratory tract infections, antidiarrheal Fruits: carminative, laxative, diuretic BAI, CAT, CHA, COS, ERI, FOR, LPA, LRI, MEN, SFE, SJU Azorella biloba (Schltdl.) Part not specified: bequic, No biological test No data Wedd. expectorant, anti-gonorrhea Kiesling 1601 (SI) JUJ, COR, SAL, TUC Azorella compacta Phil. Aerial parts: stimulant, stomachic, Dried aerial parts: Dried entire plant. Azorellanol, Yareta, jareta, puna yareta contraceptive antimycobacterial and deacetyl azorellanol, mulina-11-13- Cocucci 2692 (CORD) Dried entire plant, decoction: to antitrypanosomal activity dien-20-oic acid , mulinol, 11-12-epoxy treat urinary and respiratory tract mulin-13-en-20-oic acid: diterpenes infections, antidiarrheal; infusion: for asthma, colds, diabetes, and bronchitis CAT, JUJ, SAL Azorella cryptantha (Clos) Part not specified: bequic, No biological test Entire plant. Azorellolide, Reiche expectorant, antigonorrheal dihydroazorellolide, yaretol,1- Pasto de vega, yerba del CAT, LRI, MEN, SJU α,10β,4β,5α-diepoxy-7α-germacran-6β- soldado, yareta ol Ulibarri 1476 (SI) Azorella filamentosa Lam. Dried aerial parts: Dried aerial parts: No data

Pennington 376 (SI) antimycobacterial antimycobacterial activity 85 TDF

86

Azorella monantha Clos Root: antitussive, diuretic No biological test Leaves + stem. Quercetin, Tomo34(1-2):7-365.2009 Yareta, le ña de pied ra, kurá CHU, MEN, NEU, RNE, SCR, isorhamnetin: flavonols. mamüll TDF Cocucci 2179 (CORD) Azorella trifurcata (Gaertn.) Part not specified: antitussive, Dried aerial parts: Fresh entire plant. 1-acetoxy Pers. antirheumatic, expectorant, antimycobacterial activity; effect pentadeca-cis-2-9-diene-4-6-diyn-8-ol,: Llareta antiseptic, balsamic and for on sperm motility and viability alkenynol; isorhamnetin: flavonol; 4’- Cocucci 2419 (CORD) venereal diseases methoxy flavone: flavone; mulinolic CHU, MEN, NEU, RNE, SCR, acid, mulinenic acid, azorellan-17,13- SJU, TDF β-olide: diterpenes Bolax gummifera (Lam.) Aerial parts: to treat external Dried aerial parts: crown gall Part not specified. Bornyl-para- Spreng. wounds tumor inhibition hydroxy-trans-cinnamate: bornyl p- Gomero Dried aerial parts, infusion: to Fresh dried aerial parts: coumarate, bornyl ferulate Alboff s.n. (LP) treat wounds antibacterial and SCR, TDF anticrustacean activity Cyclospermum Aerial parts: abluent, antiseptic, No biological test Aerial parts essential oil. leptophyllum (Pers.) cicatrizant Thymoquinol dimethyl ether, isothymol Sprague Fruits: carminative, antinephritic, methyl ether, thymol methyl ether, Apio cimarrón, apio silvestre antirheumatic carvacrol methyl ether, p-cymene, γ- Apium leptophyllum (Pers.) F. BAI, CAT, CHA, CHU, COR, COS, terpinene, β-pinene, β-caryophyllene, α- Muell. ERI, FOR, JUJ, LPA, MIS, RNE, humulene, germacrene-D, germacrene- Hunziker 7753 (CORD) SAL, SDE, SFE, SJU, SLU, TUC B (sub nom. A. leptophyllum) Daucus pusillus Michx. Dried entire plant (dried and No biological test Seed. Astragalin, iso quercitrin: Zanahoria silvestre smoked): to treat paralysis caused flavonol; cosmosiin, cynaroside Subils 834 (CORD) by water on the brain; decoction: febrifuge, for snakebite Part not specified, decoction: antivenin

Root: diuretic KURTZIANA BAI, CHU, COR, COS, ERI, LPA, MIS, NEU, RNE, SDE, SFE, SLU Eryngium agavifolium Griseb. Root: pectoral, stomachic No biological test Dried root. Falcarinolone: alkenynone Serruchón COR, SDE, SLU C5 Hunziker 9677 (CORD)

Eryngium coronatum Hook. Root: icteric No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina & Arn. BAI, CHA, COR, COS, ERI, FOR, Carda, falso caraguatá JUJ, LPA, MIS, SDE, SFE, TUC Hunziker 21763 (CORD) Eryngium ebracteatum Root: diuretic No biological test No data Lam. BAI, CAT, CHA, COR, COS, ERI, Carda FOR, JUJ, LPA, LRI, MIS, RNE, Hunziker 11364 (CORD) SAL, SDE, SFE, SJU, TUC Eryngium eburneum Decne. Rhizome: icteric, diuretic No biological test No data Falso caraguatá, falso cardo, BAI, CHA, COS, ERI, FOR, MIS, serrucheta, carda SDE, SFE Pedersen 9612 (CORD) Eryngium echinatum Urb. Rhizome: icteric, diuretic No biological test No data Hunziker 1569 (CORD) BAI, CHA, COS, ERI, MIS, SFE Eryngium ele gans Cham. & Root: icteric No biological test No data Schltdt. BAI, CAT, CHA, COR, COS, ERI, Carda FOR, JUJ, LPA, MIS, SAL, SDE, Ariza Espinar 3226 (CORD) SFE, TUC Eryngium horridum Malme Dried aerial parts: diuretic Dried aerial parts: cytotoxic No data Caraguatá, carda Root: icteric activity Hunziker 10650 (CORD) Rhizome: purgative BAI, CHA, COR, COS, ERI, MIS, SDE, SFE, SLU Eryngium nudicaule Lam. Root: icteric, abluent Dried aerial parts: antimalarial No data Ariza Espinar 618 (CORD) BAI, CHA, COR, COS, ERI, LRI, activity MIS, SFE, SLU Eryngium pandanifolium Dried aerial parts: diuretic Aerial parts: cytotoxic activity No data Cham. & Schltdl. Root + leaf: aperitve, diuretic, Cardo, caraguatá astringent, depurative, Kurtz 2073 (CORD) emmenagogue, digestive BAI, CHA, COS, ERI, MIS, SFE Eryngium panicula tum Cav. Root + rhizome: hepatic/intestinal Dried seed: plant germination Dried seed. Cyclohexa-2-5-dienyl,2-4- & Dombey ex F. Delaroche Dried leaf, infusion: antiseptic, inhibition 4-trimethyl-3-formyl, angelate. Chupalla, cardilla, cardon- cicatrizant, astringent cillo, chupala, cupalla BAI, CHU, LPA, NEU, RNE 87 Barboza 1216 (CORD)

8

Gymnophyton Part not specified: carminative No biological test. Leaves + stem. Quercitin: flavonol; Tomo34(1-2):7-365.2009 polycephalum (Gillies & CAT, LRI, MEN, SAL, SJU 6,8-di-C-glycosyl chrysoeriol, Hook.) Clos 4’methoxy flavone, 7-O-monoglycoside Ariza Espinar 2951 (CORD) flavone Hydrocotyle bonariensis Aerial parts: for treating wounds No biological test Seed. Iso quercitrin: flavonol Lam. externally, diuretic, hydrogogue, Paragüita, oreja de agua, vulnerary redondita de agua, cucharita, Entire plant, decoction: for sombrilla de sapo urinary disorders Hunziker 11414 (CORD) Dried root, infusion: anti- inflammatory and toothache BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC. Hydrocotyle callicephala Part not specified: febrifuge, for No biological test No data Cham. feet edema, to relieve acne Deginani 1305 (SI) MIS, SFE Hydrocotyle ranunculoides Juice fresh: tonic, emetic, No biological test Dried entire plant. Ranunculoside I, L. f. depurative, diuretic, hepatic, ranunculoside II, ranunculoside III, Redondita de agua, cucharita, hydrogogue, pectoral hederagenic acid, barringtogenol C: piragüita, perejil de agua, BAI, CHA, CHU, COR, COS, triterpenes; ranunculoside VII: redondita, sombrilla de sapo, ERI, FOR, JUJ, LPA, LRI, MEN, triterpene tembladerilla, verdolaga NEU, RNE, SAL, SCR, SDE, SFE, palustre SJU, SLU, TUC Hunziker 2326 (CORD) Laretia acaulis (Cav.) Gillies Aerial parts: tonic, digestive No biological test Dried entire plant. Azorellanol, 7- & Hook. MEN, SJU deacetyl azorellanol: diterpenes; Llareta mulinolic acid, mulinolic acid,13-epi, Kurtz 14 (CORD) mulin-11-13-dien-20-oic acid:

diterpenes KURTZIANA Mulinum crassifolium Phil. Dried aerial parts: antidiabetic, No biological test Dried aerial parts. Mulinic acid: Chuchicaña antiseptic, balsamic, antitussive, to diterpene Cabrera 8790 (LP) treat intestinal disorders Essential oil. Bornyl acetate, camphor, SAL citronellol: monoterpenes

BARBOZA, G.E.etal.MedicinalfloraofArgentina Mulinum echinus DC. Part not specified: antiseptic, No biological test No data Mulinum ulicinum auct. non balsamic, expectorant Gillies & Hook. Dried leaf, infusion: Hosseus 603 (CORD) emmenagogue, antidiabetic (sub nom. M. ulicinum) CHU, MEN, NEU, RNE, SJU Mulinum famatinense H. Part not specified: venereal No biological test No data Wolff disease, depurative, antitussive, Chuchicaña, chuquicaya antidiabetic, antiseptic, balsamic Hieronymus 360 (CORD) JUJ, LRI, SAL Mulinum spinosum (Cav.) Root: urinary, against toothache Aerial parts: trypanocidal Aerial part. Mulinolic acid, mulinenic Pers. BAI, CHU, LPA, MEN, NEU, activity; effect on sperm motility acid, azorellan-17,13- β-olide: Neneo, yerba negra, palo RNE, SCR, SJU and viability diterpenes negro, hierba de la culebra Cocucci 2362 (CORD) Osmorhiza chilensis Hook. Part not specified: hepatic, No biological test No data & Arn. digestive Cacho cabra, anís de campo, Root: for eye diseases ñukin Aerial parts: aromatic Bernardello et al. 563 (CORD) CHU, MEN, NEU, RNE, SCR, TDF Osmorhiza depauperata Part not specified: aromatic No biological test No data Phil. CHU, NEU, RNE, SCR, TDF Hunziker 8206 (CORD) Sanicula crassicaulis Poepp. Part not specified: hemostatic No biological test No data ex DC. CHU, MEN, NEU Pata de león, cilantro del cerro Bernardello 564 (CORD) Sanicula graveolens Poepp. Part not specified: medicinal Aerial parts: radical scavenging Aerial part. Caffeic acid derivatives; ex DC. CHU, MEN, NEU, RNE activity quercitin Cilantro silvestre, cilantro del cerro, perejil del monte, asta de cabra Barboza 212 (CORD)

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APOCYNACEAE Latex: for the treatments of warts No biological test No data Tomo34(1-2):7-365.2009 Amblyopetalum coccineum BAI, CAT, CHA. COR, ERI, (Griseb.) Malme JUJ,LRI, SAL, SLU, TUC Palo leche Tur 1115 (SI) Araujia angustifolia (Hook. Root + fruit: galactagogue No biological test Fruit latex: Araujiain aI, aII, aIII: & Arn.) Decne. Latex: fungicidal, against cysteine proteases Tasi toothache Burkart 21341 (SI) BAI, CHA, COS, ERI, FOR, SDE, SFE Araujia sericifera Brot. Fruits: galactogogue Fruit latex: proteolytic activity Dried root. Caudatin glycoside, Tasi (sub nom. A. hortorum) incisagenin glycoside: steroids Araujia hortorum E. Fourn. BAI, COS, ERI, MIS, SFE (sub nom. A. hortorum) Hunziker 16325 (CORD) Fruit latex. Araujiain h I, h II, h III: cysteine endopeptidases (sub nom. A. hortorum) Asclepias flava Lillo Medicinal No biological test No data Leche tres CAT, JUJ, LRI, SAL, TUC Aquino 223 (CORD) Asclepias mellodora A. St.- Aerial parts: alexipharmic No biological test Leaf + stem. Bufadienolides, Hil. Root + leaf: emetic flavonoids, phenols, triterpenes Yerba de la víbora BAI, CHA, COR, COS, ERI, FOR, Hunziker 11561 (CORD) JUJ, LPA, MIS, RNE, SAL, SDE, SFE, SLU, TUC Aspidosperma polyneuron Part not specified: expectorant, Bark: antimalarial activity Leaf essential oil. Kaurene: diterpene; Müll. Arg. anticarrhal linalool, [α]-copaene, [β]- Peroba rosa, sobro, peroba Bark: febrifuge, antimalarial, caryophyllene; pentadecanal, hexenol amargosa astringent and hexadecanone: fatty acid

Lillo 10562 (LIL) MIS derivatives KURTZIANA Leaf + bark. Polyneuridine, aspidospermine, quebrachamine: indole alkaloids Bark. Normacusine-B: indole alkaloid

BARBOZA, G.E.etal.MedicinalfloraofArgentina Aspidosperma quebracho- Root: abortifacient, depurative Bark: spasmolytic and Bark. Aspidosamin, aspidospermine, blanco Schltdl. Bark: antidysneic, anti-asthmatic, antimalarial activity; adrenergic quebrachamine, yohimbine: indole Quebracho blanco, quebracho antitussive, cephalalgic, febrifuge, receptor blocker (α-1 and α-2) alkaloids blanco llorón, guarirobá oxytocic; decoction: antisyphilitic, Aerial parts: antioxidant Leaf + bark. Akuammidine: indole Bernardello 422 (CORD) antidysenteric, pectoral, abortive and activity alkaloid; α-amyrin: triterpene for stomach-ache; liver disorders, Leaf. Flavonoids analgesic; infusion: for fertility regulation, antifebrile, emetic, anticolic, hallucinogen, cicatrizant, contraceptive, emmenagogue CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, SAL, SDE, SFE, SJU, SLU, TUC Forsteronia glabrescens Aerial parts: febrifuge No biological test No data Müll. Arg. CHA, COS, ERI, FOR, MIS, SAL, Isipó, isipó de San Vicente, SFE isipó cambüí, enredadera leche Morrone 1637 (SI) Funastrum clausum (Jacq.) Part not specified: tonic, Latex: proteolytic activity Latex. Funastrain CII: cysteine Schltr. stimulant Aerial parts: weak endopeptidase Funastrum bonariense (sub nom. F. bonariense) antimicrobial activity (Hook. & Arn.) Schltr. BAI, CHA, COS, ERI, FOR, JUJ, Barboza 1689 (CORD) SAL, SDE, SFE Funastrum flavum (Decne.) Part not specified: tonic, No biological test No data Malme stimulant Burkart 8962 (SI) BAI, COS, ERI, MIS, SFE Funastrum gracile (Decne.) Stem: anti-peristaltic, stomachic, No biological test No data Schltdl. hepatic Tramontana CAT, CHA, COR, FOR, JUJ, LRI, Hunziker 6513 (CORD) SAL, SDE, SFE, TUC Macrosiphonia pe traea (A. Root: digestive No biological test No data St.-Hil.) K. Schum. Leaf : hypoglucemic Flor de piedra, nocturno BAI, CHA, COR, COS, ERI, FOR, Ariza Espinar 692 (CORD) LPA, MIS, SAL, SDE, SFE, SLU 91

92

Mandevilla laxa (Ruiz & Entire plant: drastic No biological test Seed oil. Linoleic acid, oleic acid, Tomo34(1-2):7-365.2009 Pav.) Woodson CAT, COR, JUJ, SAL, TUC palmitic acid: lipid Jazmín del campo, jazmín de Chile, jazmín de Jujuy, sacha huasca blanca Cocucci 175 (CORD) Mandevilla pentlandiana Entire plant: drastic Aerial parts: antioxidant Dried root. β-amyrenone, β-amyrin, (A. DC.) Woodson CAT, COR, COS, JUJ, LRI, SAL, activity lupenone, ursolic acid: triterpenes; 5-α- Cantero et al. s.n. (RIOC 834) SFE, SLU, TUC 3-β-hydroxy-24-epsilon-ethyl cholest- 22-en-6-one, 24-epsilon-ethy cholest-5- en-3-β-ol: steroids; β-curcumene: sesquiterpene; digitoxigenin, echujin: cardenolides Seed oil. Palmitic acid: lipid Morrenia brachystephana Aerial parts: galactogogue Latex: proteolytic activity Fresh fruit latex. Morrenia protease: Griseb. Root: galactagogue, antiwarty, protein; alkaloids, flavonoids Tasi, doca against toothache Latex. Morrenain BI, BII: papain-like Hunziker 16174 (CORD) Latex: emollient, for warts endopeptidases BAI, CAT, COR, COS, ERI, FOR, Dried aerial parts. Alkaloids present JUJ, SAL, SDE, SFE, SLU, TUC Morrenia odorata (Hook. & Root: galactagogue, anti-warty, Stem latex: proteolytic activity Leaf. Alkaloids Arn.) Lindl. against toothache Petiole + stem. Protelytic enzymes Tasi, doca BAI, CAT, CHA, COR, COS, ERI, Latex. Morrenain OII: proteinase Cocucci 16456 (CORD) FOR, JUJ, LPA, LRI, MEN, SAL, SDE, SFE, SJU, TUC Morrenia stuc kertiana (Kurtz Latex: abluent No biological test No data ex Heger) Malme COR, SFE Tasi crespo, tasi del zorro, tasillo Ariza Espinar 2849 (CORD) KURTZIANA Philibertia gilliesii Hook. & Latex fruit: proteolytic activity Latex fruit: proteolytic activity Latex fruit. Philibertain GI: cysteine Arn. BAI, CAT, CHA, CHU, COR, endopeptidase Farol, sombrilla, capanilla, COS, ERI, FOR, JUJ, LRI, MEN, cortachina, farolito, sombrilla RNE, SAL, SDE, SJU, SLU, TUC Ariza Espinar 1698 (CORD)

Rauvolfia schuelii Speg. Root cortex: emetic, purgant, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Lecherón del monte, lecherón sedative, hypotensive negro, lecherón amarillo, CAT, JUJ, SAL, TUC leche-leche, tinajero Morrone 3004 (SI)

Rauvolfia sellowii Müll. Root: antihypertensive Root: hypotensive activity Leaf. Sellowiine (N1-demethyl-20- Arg. Cortex: hypotensor, antimalarial deethyl suaveoline), perakine, Klein 9119 (SI) MI raucaffrinoline, vomilenine, 19α,20α- epoxy-akuammicine, picrinine,12- demethoxytabernulosine: alkaloids Tabernaemontana Plant: antidote for snakebites, to Stem bark: analgesic, anti- Leaf, seed + root. , catharinensis A. DC. relieve toothache and earache, to inflammatory activity and toxic tabersonine, olivacine, hydroindolenine, Casca de cobra, sapirangui, cure warts, vermifuge, abortive Root bark, stem bark, catharinensine, jazmín, palo-víbora, Leaf: for treating tumors and pericarp + seed: trypanocidal decarbomethoxyvoacamine, horquetero, sapiranguí, healing wounds (snakebite) activity tabernamine, voacamine: alkaloids; zapiranguí-guazú Bark: anthelmintic Stem: antileishmanial activity vanillic acid, , gentisic Tabernaemontana australis (sub nom. T. australis, P. Leaf: anti-inflammatory, acid, salicylic acid: phenolic acids Müll. Arg. australis) analgesic, and proteolytic Root: 12-methoxy-4- Peschiera australis (Müll. Latex: for cutaneous affections activity methylvoachalotine, coronaridine, Arg.) Miers CHA, COS, ERI, FOR, MIS, SFE Leaf + seed: antineoplasic coronaridine hydroxyindolenine, Barboza 1676 (CORD) activity voacangine, hydroxyindolenine, heyneanine, vobasine: indole alkaloids Seed. Oleic acid (sub nom. P. australis) Vallesia glabra (Cav.) Link Root + stem: drastic, febrifuge Bark: antimalarial activity Leaf + stem. Vallesine, aspidospermine, Ancoche, teta de gata, Cortex: laxant, febrifuge 11-methoxydichotine, apparicine, ancuchi, engorda, ancochi Dried branches: for rheumatism tubotaiwine, vincadifformine, (minus)- Hunziker 10796 (CORD) Leaf: to cure warts rhazinilam, aspidospermatine, CAT, CHA, COR, FOR, JUJ, LRI, condylocarpine, haplocidine, 18- SAL, SDE, SJU, TUC oxohaplocidine: alkaloids AQUIFOLIACEAE Ilex argentina Lillo Leaf, infusion: excitant, digestive, Dried leaf: antioxidant activity, Dried stem. Theobromine: alkaloid Roble tucumano, palo de diuretic, choleretic, radical scavenging effect. Leaf. Caffeic acid, chlorogenic acid, 3,4- yerba, naranjillo, roble, árbol hypocholesteremic, dicaffeoylquinic acid, 3,5-dicaffeoylquinic

de la yerba, roblina, roble de hepatoprotective and bitter taste acid and 4,5-dicaffeoylquinic acid: caffeoyl 93 Tucumán CAT, JUJ, SAL, TUC derivatives; quercetin, rutin and kaempferol: Zuloaga 7488 (SI) flavonoids; rotundic acid: triterpene

Ilex brevicuspis Reissek Leaf, infusion: choleretic, Leaf: increase in bile flow and Leaf. Caffeic acid, chlorogenic acid, 94 Caona, cauna, siete sangrías hypocholesteremic, hepatoprotective intestinal transit; antioxidant 3,4-dicaffeoylquinic acid, 3,5- Tomo34(1-2):7-365.2009 Schinini 10632 (CTES, SI) COS, MIS activity dicaffeoylquinic acid and 4,5- dicaffeoylquinic acid: caffeoyl derivatives; quercetin, rutin, kaempferol: flavonoids Ilex dumosa var. guaranina Leaf, infusion: choleretic, No biological test Leaf. Caffeic acid, chlorogenic acid, Loes. hypocholesteremic, 3,4-dicaffeoylquinic acid, 3,5- Yerba señorita, caá-berá, caá- hepatoprotective dicaffeoylquinic acid, 4,5- chirí, caá-miní, caá-verá, COS, MIS dicaffeoylquinic acid: caffeoyl cauna derivatives; quercetin, rutin, Schinini 27066 (CTES) kaempferol: flavonoids Ilex paraguariensis A.St.- Aerial parts: galactogogue, Leaf: increase in bile flow; Leaf. Caffeic acid, chlorogenic acid, 3,4- Hil. cicatrizant antioxidant and anticancer dicaffeoylquinic acid, 3,5-dicaffeoylquinic , caá, árbol del Leaf, infusion: against the effect; LDL oxidation inhibition; acid, 4,5-dicaffeoylquinic acid, 5- mate influenza and the scurf, tonic, potential therapeutic and/or caffeoylquinic acid: caffeoyl derivatives; Cocucci 418 (CORD) refrigerant, diuretic, digestive, prophylactic use in caffeine (= 1,3,7-trimethylxanthine), stimulant, choleretic, eupeptic, cardiovascular disorders theobromine (= 3,7-dimethylxanthine), hypocholesteremic, theophylline (= 1,3-dimethylxanthine): hepatoprotective purine alkaloids; quercetin, rutin, COS, MIS kaempferol: flavonoids; matesaponin 1; ursolic acid 3-O-[β-D-glucopyranosyl- (1→3)-[α-L-rhamnopyranosyl- (1→2)]]-α- L-arabinopyranosyl]-(28→1)-β-D- glucopyranosyl ester = matesaponin 2, ursolic acid 3-O-[β-D-glucopyranosyl- (1→3)-α-L-arabinopyranosyl]-(28→1)- [β-D-glucopyranosyl-(1→6)-β-D- glucopyranosyl]ester = matesaponin 3, ursolic acid 3-O-[β-D-glucopyranosyl- (1→3)-[α-L- rhamnopyranosyl-(1→2)]]-α- KURTZIANA L-arabinopyranosyl]-(28→1)-[β -D- glucopyranosyl-(1→6)-β-D- glucopyranosyl]ester = matesaponin 4; matesaponin 5; guaicin B, nudicaucin C: saponins; vitamins; polyphenolic compounds

BARBOZA, G.E.etal.MedicinalfloraofArgentina Ilex theazans Mart. ex Leaf, infusion: choleretic, Dried leaf: antioxidant activity, Leaf. Caffeic acid, chlorogenic acid, Reissek hypocholesteremic, radical scavenging effect. 3,4-dicaffeoylquinic acid, 3,5- Giberti 261 (BACP, SI) hepatoprotective dicaffeoylquinic acid, 4,5- MIS dicaffeoylquinic acid: caffeoyl derivatives; quercetin, rutin, kaempferol: flavonoids; arbutin,2'- sulfonyl: benzenoid; caffeine: alkaloid; rotundic acid: triterpene. ARALIACEAE Oreopanax kuntzei Harms Bark: for hernia and prolapse No biological test No data Higuerilla JUJ, SAL Novara 11284 (CORD) Raukaua laetevirens (Gay) Cortex: diaphoretic No biological test No data Frodin CHU, NEU, RNE, SCR Sauco del diablo Burkart 26508 (SI) Schefflera morototoni (Aubl.) Part not specified: to treat No biological test No data Maguire, Steyerm. & Frodin respiratory affections Zuloaga 7023 (SI) CHA, COS, FOR, MIS ARISTOLOCHIACEAE Aristolochia angustifolia Entire plant, infusion: No biological test No data Cham. emmenagogue; decoction: to treat Alumbre del campo urinary tract infections and Cristóbal 260 (LIL) antidiarrheal COS, MIS

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Aristolochia argentina Entire plant, infusion: diuretic, Dried aerial parts: insecticide, Root. Allantoin: alkaloid; argentinine: Tomo34(1-2):7-365.2009 Griseb. diaphoretic, antidiarrheal antioxidant, antibacterial, and isoquinoline alkaloid Charrúa, charruga, mil Root: antiseptic, diaphoretic, antifungal activity Dried rhizome. Aristolactams Ia, II, hombres, patito, buche de diuretic, emmenagogue, Root: anti-ulcerogenic effect III, IIIa, AIa, AIIIa, CII, DII : alkaloids pavo antirheumatic, for treating Dried underground parts. Aristolochic Di Fulvio 138 (CORD) poisoning and pruritus acid; methyl ester of aristolochic acid, CAT, CHA, COR, JUJ, LRI, MIS, Aristolochic acid I methyl ester, SAL, SDE, SJU, SLU, TUC aristolochic acid Ia, 6-methoxyaristolochic acid C, aristolochic acid C, aristolochic acid IV (6-methoxyaristolochic acid), 6,7- Dimethoxy-3,4-methylenedioxy-10-nitro- 1-phenanthroic acid (aristolochic acid V), 6-Hydroxy-7-methoxy-3,4- methylenedioxy-10-nitro-1-phenanthroic acid (aristolochic acid Va), 2-Hydroxy-8- methoxy-3,4-methylenedioxy-10-nitro-1- phenanthroic acid (aristolochic acid VIa), 7-Hydroxy-8-methoxy-3,4- methylenedioxy-10-nitro-1-phenanthroic acid (aristolochic acid VIIa), Aristolochin (aristoloside) Plant essential oil. Argentilactone, undecatriene isomers; (S)-linalool, trans- ocimene, myrcene, limonene, α-terpenyl acetate, α-phellandrene, β-phellandrene, 1,8-cineole, β-cyclocitral, isobornyl formate, camphene, α-pinene, β-pinene: monoterpenoids; β-farnesene, β-elemene, δ-elemene, germacrene D, cyperene, bicyclogermacrene, α-humulene, β- caryophyllene, isocaryophyllene, selina- KURTZIANA 3,7(11)-diene, β-gurjunene, spathulenol, α- trans-bergamotene, (−)-α-copaene, ishwarane, β-bourbonene: sesquiterpenoids; (−)-kaur-16-ene: diterpenoids

BARBOZA, G.E.etal.MedicinalfloraofArgentina Aristolochia elegans Mast. Aerial parts: antirheumatic Whole plant: uterus contraction Plant essential oil. (S)-linalool, Mil hombres hembra, patito, COS, ERI, JUJ, MIS, SFE stimulating activity; antimitotic limonene, 1,8-cineole, borneol, flor de patito and antiviral activity bornanol, camphene, α-pinene, β- Galera 641 (CORD) pinene: monoterpenoids; β-farnesene, farnesol, (Z)-(R)-nerolidol, (E)-(R)- nerolidol, α-bisabolene, α-curcumene, β-elemene, δ-elemene, γ-elemene, germacrene B, germacrene D, hedycaryol, mollislactone, α-humulene, bicyclogermacrene, β-caryophyllene, isocaryophyllene, caryophyllene oxide, caryophyllenol I, Δ1(10) –aristolene, γ- cadinene, δ-cadinene, γ-muurolene, T- muurolol, epi-cubenol, T-cadinol, α- cadinol, cubenol, guaiol, calamenene, α-calacorene, 6,9-guaiadiene, guaiazulene, spathulenol, viridiflorol, globulol, α-cubebene, β-cubebene, α- himachalene, longifolene, isolongifolene, (−)-α-copaene, β- bourbonene, bourbonol, aristololide, caparrapidiol: sesquiterpenoids; (E)- phytol, ent-16β(H)-kaurane, kauranal, kauranoic acid, 16α,17-epoxykaurane, ent-kauran-16α,17-diol, (−)-kaur-15-en- 17-ol, ent-15β,(16β)-epoxykauran-17- ol, aristolin, aristoloin I, sodium aristolochate I (aristolochate I), pontevedrine: diterpenoids

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98

Aristolochia elegans Mast. Root essential oil. α-pinene, β-pinene, Tomo34(1-2):7-365.2009 (continuation) camphene, 1,8-cineole, borneol, bornyl acetate: monoterpenoids; α-copaene, isocaryophyllene, β-elemene, β- caryophyllene, 6,9-guaiadiene, allo- aromadendrene, α-humulene, γ- muurolene, α-bisabolene, δ-cadinene, γ- cadinene, calamenene, calacorene, guaiazulene, (Z)-nerolidol, (E)- nerolidol, cubenol, epi-cubenol, hedycaryol, guaiol, T-cadinol: sesquiterpenoids; aristolene, ylangene, longicyclene, p-Mentha-1(7),8(10)- dien-9-ol, methyl citronellate, limonene Stem essential oil. Linalool, cyclocitral: monoterpenoids; α- cubebene, α-copaene, β-bourbonene, isocaryophyllene, β-elemene, β- gurjunene, β-caryophyllene, longifolene, α-humulene, γ-muurolene, germacrene D, bicyclogermacrene, δ- cadinene, trans-β-farnesene, (E)- nerolidol, β-caryophyllene oxide, spathulenol, T-muurolol, α-cadinol: sesquiterpenoids; 1-octen-3-yl acetate, 1-octen-3-ol, 3-octanol; aristolin: diterpene ester of aristolochic acid Aristolochia esperanzae Aerial parts: stimulant No biological test Dried root. Kolavenic acid methyl Kuntze Dried root, infusion: ester, (2S,5R,8R,9S,10R)-2- Patito, contrayerba emmenagogue hydroperoxy-ent-3-cleroden-3,13- KURTZIANA Novara 11092 (CORD) Dried leaf + stem, infusion: diene-15-oic acid methyl ester, 2- antirheumatic oxokolavenic acid methyl ester, populifolic acid methyl ester, (2S,5R,8R,9S,10R)-2-hydroperoxy-ent-

BARBOZA, G.E.etal.MedicinalfloraofArgentina Aristolochia esperanzae Part not specified: emmenagogue 3-cleroden-15-oic acid methyl ester, 2- Kuntze CHA, FOR, JUJ, SAL oxopopulifolic acid methyl ester: (continuation) diterpenoids; β-patchoulene, α- aromadendrene; methyl (5R,8R,9S,10R)-ent-3-cleroden-15-oate [methyl populifoloate]: clerodane diterpenoids; (5R,9S,10S)-ent-Labd- 8(17),13-dien-15-oic acid [copalic acid], (5R,9S,10S)-ent-Labd-6β- hydroxy-8(17),13-dien-15-oic acid, methyl (5R,8R,9S,10S)-ent-labd- 8(17),13-dien-15-oate [methyl copalate], methyl (5R,9S,10S)-ent-labd- 6β-hydroxy-8(17),13-dien-15-oate: labdane diterpenoids Dried leaf. Cubebin, cubenin,3-4- dimethoxy-3-4-demethylenedioxy, epi eudesmin: lignan; copalic acid, ent- labd-6β-ol-8(17),13-dien-15-oic acid: labdane diterpenes Foliar epicuticular waxes of leaves. β- amyrin, lupeol, epifriedelinol, ursolic acid: triterpenoids Part not specified. Aristolochic acid: polycyclic Aristolochia fimbriata Cham. Leaf: abortifacient, against No biological test Part not specified. Aristolochic acid: Mil hombres, patito, flor de toothache polycyclic patito, pajarito Part not specified: emmenagogue Doering s. n. (SI) BAI, CHA, COS, ERI, FOR, MIS, SFE

9

Aristolochia gibertii Hook. Root and leaf: anti-inflammatory, No biological test Stem + leaf essential oil. trans-ocimene, 100 Mil hombres, ipepú, flor de digestive myrcene, limonene, β-phellandrene, 1,8- pitito, patito, mil hombre Part not specified: emmenagogue cineole, isobornyl formate, camphene, α- Tomo34(1-2):7-365.2009 hembra CHA, COS, FOR pinene, β-pinene, carvone, Δ-2-carene, Δ- Barboza 392 (CORD) 3-carene, sabinene, tricyclene: monoterpenoids; (E)-(R)-nerolidol, β- elemene, δ-elemene, germacrene D, aristolactone, bicyclogermacrene, α- humulene, β-caryophyllene, β-selinene, δ- cadinene, β-calacorene, α-calacorene, α- aromadendrene, allo-aromadendrene, spathulenol, (−)-α-copaene, β-bourbonene: sesquiterpenoids Aristolochia macroura Gómes Root: emmenagogue, abortifacient, Plant: cytotoxic activity Plant essential oil. β-farnesene, (E)- Milhombres, patito coludo, antirheumatic. (R)-nerolidol, γ-elemene, δ-elemene, α- flor del patito, contrahierba, Leaf: alexipharmic, aphrodisiac humulene, (−)-α-copaene: jarro, isipomilhombres BAI, CHA, COS, ERI, MIS, SFE sesquiterpenoids Martínez 516 (CORD) Aristolochia stuckertii Speg. Root: antiseptic, diaphoretic, No biological test No data Charrúa, mil hombres diuretic, emmenagogue, Subils 322 (CORD) antirheumatic BAI, COR, COS, ERI, MIS, SFE Aristolochia triangularis Entire plant, infusion: Bark: antimitotic activity Entire plant. Cubebin,3-4-dimethoxy- Cham. abortifacient, emmenagogue, for Dried bark: insecticide activity 3-4-demethylenedioxy: lignan Mil hombres, cipó, patito heart pains, for lumbago, tonic Dried root: anti-inflammatory Dried root. 10-Amino-2,4-dimethoxy- Sehnem 2130 (CORD) Root: alexipharmic, hydrogogue, activity phenanthrene-1-carboxylic acid lactam, 6 antirheumatic, anti-syphilitics, Whole plant: cytotoxic activity aristolactam AII, aristolactam CII, disease venereal, stimulant, aristolactam A Ia, A IIIa: alkaloids; digestive, contraceptive, diuretic, aristolochic acid: polycyclic; asimilobine, diaphoretic, astringent dehydro: 4-5-dioxo, cepharadione a:

Dried bark, infusion: isoquinoline alkaloid; kaur-16-en-19-ol, (-): KURTZIANA antirheumatic, abortive, diterpene; triangularine A, triangularine emmenagogue, diaphoretic, B, aristolochic acid Iva, 4,5- diuretic, antiseptic, antidote; dioxodehydroasimilobin treatment of wounds and skin Fresh root. β-bisabolene, germacrene diseases A: sesquiterpene Fresh leaf essential oil. Linalool: monoterpene

Aristolochia triangularis Leaf, infusion: abortifacient, Root + stem. β-sitosterol: steroid BARBOZA, G.E.etal.MedicinalfloraofArgentina Cham. emmenagogue Root + stem essential oil: (E)-(R)- (continuation) BAI, COS, ERI, MIS nerolidol, β-elemene, δ-elemene, (−)-α- copaene: sesquiterpenoids; ent- 16ββ(H)-kaurane, 16α,17- epoxykaurane, ent-kauran-16α,17-diol, (−)-kaur-15-en-17-ol, ent-15β,(16β)- epoxykauran-17-ol (−)-kaur-16-ene, (−)-kaur-16-ene-18-ol, (−)-kaur-16-en-18-al, (−)-kaur-16-en- 18-oic acid, ent-16β,17-epoxykaurane, ent-16β(H)-kauran-17-oic acid, (−)- kauran-16α-ol-18-al: diterpenoids ASTERACEAE Acanthospermum australe Entire plant: antineoplasic, diuretic, Dried entire plant: antimalarial Dried aerial parts. Acanthamolide, (Loefl.) Kuntze astringent, vulnerary, antimalarial, and antimicrobial activity; acanthospermal, spathulenol: Torito, tapecué, abrojillo, contraceptive, febrifuge; to treat fertilization inhibition sesquiterpenes; acanthoaustralide, iso yerba de la oveja, tapekué, cancer and malignant tumors, for Aerial parts: cytotoxic activity acanthoaustralide: 1-O-acetate: tirirati fertility regulation diaphoretic, Part not specified: diterpenes; acanthospermal A, Subils & Moscone 3276 abortifacient, anti-inflammatory, lipoxygenase inhibition germacrene C: sesquiterpenes; , (CORD) antirheumatic, antiseptic 5-7-4'-trihydroxy-3-6-dimethoxy Dried aerial parts, infusion: flavone: flavonol diuretic; febrifuge and antidiarrheal BAI, COR, COS, ERI, MIS, SFE, SLU Acanthospermum hispidum Aerial parts: diuretic, astringent, Dried aerial parts: sweetening Aerial parts. Acanthospermal B: DC. vulnerary, antimalaria, diaphoretic, effect, antileishmaniasis and sesquiterpene Cuajilla, obecha-caá, abortifacient, antitrypanosomal activity Dried aerial parts. Hispidunolide A, cuajrilla, yerba de la oveja, febrifuge, anti-gonorrhea, sudorific Leaf: antibacterial activity 15-hydroxy-14-oxo-8-β-(2-methyl- roseta, huajclilla Fresh entire plant, decoction: to buteryl-oxy) acanthospermolide, 15- Caro 3422 (CORD) produce abortion acetoxy-8-β-(iso-valeryl-oxy)-14-oxo 4- cis-5 acanthospermolide: sesquiterpenes Dried leaf. Caffeic acid:

phenylpropanoid; nevadensin: flavone 101 Dried root. 2-iso-propyl-4-methyl phenol

102

Acanthospermum hispidum Leaf, infusion: anti-gonorrhea and Tomo34(1-2):7-365.2009 DC. for dysmenorrheal (continuation) BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Achyrocline alata (Kunth) Dried aerial parts, infusion: Dried entire plant: Dried aerial parts. Apigenin, DC. digestive, sedative, stomachic, molluscicidal activity quercetin, : flavones; caffeic Güira-güira, marcela against respiratory affections Flower + stem: antiviral activity acid, chlorogenic acid, iso chlorogenic brasileira, yateí caá Dried flowers: anti-inflammatory, acid, 3, 4-dicaffeoyl quinic, 3, 5- Di Fulvio 193 (CORD) digestive, emmenagogue dicaffeoyl quinic, 4, 5-dicaffeoyl quinic BAI, CAT, COR, COS, ERI, JUJ, acids; caryophyllene: sesquiterpene LRI, MIS, SAL, SLU, TUC Inflorescence essential oil. β- caryophyllene, sesquiterpene; 1,8- cineol, trans β ocimene: monoterpene; caffeic acid, chlorogenic acid Achyrocline flaccida (Weinm.) Dried aerial parts, infusion: Aerial parts: antiviral, Dried aerial parts. Caffeic acid, DC. stimulant and excitant, febrifuge, antiherpetic, antihemolytic, chlorogenic acid, isochlorogenic acid, Amaicha, marcela amarilla, anthelimintic, antispasmodic, antileishmanial, and antioxidant 3, 4-dicaffeoyl quinic, 3, 5-dicaffeoyl marcela, marcela macho emmenagogue, anti-inflammatory activity; lipid peroxide formation quinic, 4, 5-dicaffeoyl quinic acids; 2'- Pedersen 6982 (CORD) Flowers, infusion: to treat asthma, inhibition, and radical scavenging 4-4'-trihydroxy-6'-methoxy chalcone: and to regulate menstruation effect; immunomodulating flavonoid; 3- methoxy ; uronic CHA, COR, COS, ERI, FOR, JUJ, properties; inhibitor of DNA- acids, glucuronic acids, aspartic acid, LRI, MIS, SAL, SJU, TUC polymerase (wild and Y181C glutamic acid, glycine types) and RNase H activities Achyrocline hyperchlora S. Medicinal No biological test Aerial parts. α-selinene, α-eudesmol: F. Blake CAT, JUJ, SAL, TUC sesquiterpenes; butyrophenone; eugenol, Amaicha sesamol, 2-phenylacetaldehyde, 6-methyl- Hunziker 19207 (CORD) 5-hepten-2-ona, 1,8-cineol; 3-methoxy galangin KURTZIANA

BARBOZA, G.E.etal.MedicinalfloraofArgentina Achyrocline satureioides Dried aerial parts, infusion: Aerial parts: Dried entire plant. Achyrofuran: oxygen (Lam.) DC. antidiabetic, digestive, antibacterial, hepatoprotective, heterocycle; delta cadinene,: sesquiterpene; Marcela hembra, marcela, yateí antispasmodic, anti-inflammatory, anti- immunostimulant, cytotoxic, quercetin: flavonoid; caffeic, chlorogenic and caá, vira-vira, marcela del tumor, antidiarrheal, to treat asthenia, vasodilatory, antiherpetic, isochlorogenic acids: phenolic acids; galangin, campo, marcelita tonic and stimulant antispasmodic, anti- 3-methoxy galangin-; quercetin-3- Ariza Espinar 2280 (CORD) Dried inflorescence + stem: sedative, ulcerative, antimicrobial, methylether, 2,4’-4-tri-hydroxy-6- antiseptic, antispasmodic, for antioxidant, molluscicidal, methoxychalcone, 7,4’- di-hydroxy-5- inflammation, and to aid and promote antiviral, anti-inflammatory, methoxyflavone menstruation and mutagenic activity; Dried inflorescence. Quercetin, luteolin, 3-0- Leaf, infusion: antitussive in bronchitis relaxant effect methyl quercetin, 3,7-dimethoxy-5,8- Leaf + flowers: digestive, carminative, Dried inflorescence: dihydroxyflavone: flavonoids antispasmodic, sedative, anti-ashmatic, Immunosuppressant, antitussive, hypoglycemic antioxidant, and anti- Flowers, infusion: to treat asthma, inflammatory activity analgesic, antispasmodic, anti- inflammatory BAI, CAT, CHA, COR, COS, ERI, JUJ, LPA, MIS, SAL, SDE, SFE, SLU, TUC Achyrocline tomentosa Rusby Plant: digestive, anti-emetic, anti- No biological test Dried aerial parts. 3,5-dihydroxy-7,8- Marcela, uira, uira-ira, vira-vira catharral, antitussive, expectorant dimethoxyflavone, 5,7,4’-trihydroxy-8,3’- Ariza Espinar 2821 (CORD) Flowers: digestive dimethoxyflavone: flavonoids; β-sitosterol: CAT, COR, COS, JUJ, LRI, MEN, MIS, steroid; caryatin: flavonol; caffeic acid, SAL, SJU, TUC chlorogenic acid, iso chlorogenic acid, 3, 4- dicaffeoyl quinic, 3, 5- dicaffeoyl quinic, 4, 5- dicaffeoyl quinic acids Acmella decumbens var. Root: against toothache, pectoral No biological test No data affinis (Hook. & Arn.) R. K. BAI, CAT, COR, JUJ, LPA, LRI, RNE, Jansen SDE, SLU, TUC Ñil-ñil Hunziker 7128 (CORD) Acmella decumbens (Sm.) R. Root: against toothache, pectoral Aerial parts: antimicrobial, Root. Alkamides K. Jansen var. decumbens Part not specified: sialogogue, anti-inflammatory and Zuma analgesic, pectoral antispasmodic activity Spilanthes decumbens (Sm.) A. BAI, COR, COS, ERI, MIS Root: anti-inflammatory H. Moore activity 103 Stuckert 11663 (CORD)

104 Ageratum conyzoides L. Entire plant, infusion: Dried aerial parts: analgesic, Dried entire plant. Ageconyflavone A, Tomo34(1-2):7-365.2009 Borraja del campo emmenagogue, tonic in diarrhea, anti-inflammatory, and B, C: flavone; friedelin: triterpene Chiarini 478 (CORD) for flatulent colic, tumors, antimalarial Leaf. Stigmasterol, stigmast-7-en-3-β- rheumatism leprosy, skin diseases activity ol: steroids and body swelling; to treat Essential oil: antibacterial Essential oil. 2-2-dimethyl-7-methoxy stomachache, abortifacient, in case activity Ageratochromene, 6-demethoxy of dysmenorrhea, and menorrhagia Dried leaf: anti-inflammatory ageratochromene: bornyl acetate, Aerial parts: against cough, tonic, activity bornyl formate, borneol: monoterpenes; emmenagogue, diuretic, febrifuge, β-cadinene, γ-cadinene,: sesquiterpenes; and for cold coumarin Leaf, infusion: analgesic, antispasmodic, anti-inflammatory, antipyretic, purgative; to treat cut sores, gonorrhea, and intestinal worms BAI, CHA, COS, ERI, JUJ, MIS, SAL, SFE, TUC Ambrosia elatior L. Entire plant, infusion: for fertility Dried entire plant: antibacterial Dried aerial parts. 4-β-10-α-allo Altamisa regulation, abortifacient activity aromadendrene, damsinic acid, dihydro Ariza Espinar 1827 (CORD) Aerial parts: anthelmintic, parthenolide: sesquiterpenes; purgative, emmenagogue, chlorogenic acid, iso chlorogenic acid: cephalalgic, antitussive, febrifuge phenylpropanoids Leaf + twigs, infusion: fertility Dried pollen. Cholest-7-en-3-β-ol, regulation lophenone: steroid Pollen: allergenic BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MEN, MIS, SAL, SDE, SFE, SJU Ambrosia scabra Hook. & Aerial parts and root: against Aerial parts: trypanocidal No data KURTZIANA Arn. fevers and worms activity Ajenjo del campo, altamisa, BAI artemisa Hunziker 7317 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Ambrosia tenuifolia Spreng. Aerial parts: stimulant, digestive, Aerial parts: cytotoxic, anti- Dried aerial parts. Altamisin: Altamisa hepatic, carminative, anthelmintic, inflammatory, trypanocidal, sesquiterpene; ambrosic acid, β- Ariza Espinar 3035 (CORD) cephalalgic, anti-neuralgic, leishmanicidal, antibacterial, and bisabolene, trans β-bergamotene: febrifuge antiviral activity sesquiterpenes Dried aerial parts, decoction: to Essential oil. 1-8-Cineol, , geranial, treat urinary tract infections, neral, limonene: monoterpenes antidiarrheal; infusion: febrifuge, Dried root. Stigmasterol: steroid anthelmintic, carminative, antitussive, contraceptive, abortive, for neuralgia and rheumatism, antipyretic Pollen: allergenic BAI, CHA, CHU, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, NEU, SAL, SDE, SFE, SLU, TUC spartioides Leaf: digestive Aerial parts: antioxidant Aerial parts. α-and β-pinene, Wedd. Dried branches + leaf, infusion: activity spathulenol, α-cadinol, δ and γ Pular, pulare for digestive disorders cadinene, trans-pinocarveol, α-copaene, Hunziker 24737 (CORD) JUJ, SAL E-caryophyllene, bicyclogermacrene, caryophyllene oxide, muurole-4,10(14)- dien-1β-ol, epi-α-cadinol, shyobonol Artemisia copa Phil. Aerial parts: antitussive, Dried aerial parts: antioxidant, Dried aerial parts. Achillin; Copa-copa, copa, coa, copal, carminative; for hypertension, head antimicrobial, antispasmodic, sesquiterpene; , 7- copa tola, copal tola and stomach-ache, rheumatism, antinociceptive, analgesic, methyljaceidin : flavonoids; 3,5 - Cabrera 8894 (LP) fever, respiratory diseases, for anxiolytic and anticonvulsant dihydroxy 6,7,3',4' treatment of influenza, and activity tetramethoxyflavone digestive disorders; decoction: to Leaf. Jaceidin, jaceidin-7-methylether, treat urinary and respiratory tract luteolin, kaempferol 6-methyl ether 3- infections O-rhamnoglucoside CAT, JUJ, SAL, SJU Essential oil. Jaceidin: flavonol; linalool: monoterpene; deacetyl matricarin: sesquiterpenes Artemisia echegarayi Hieron. Aerial parts: carminative, No biological test Dried leaf. Chrysoeriol: flavone; Ajenjo blanco, ajenjo stomachic : flavonol Hunziker 23706 (CORD) LRI, MEN, SJU 105

106 Artemisia mendozana DC. Aerial parts: carminative, No biological test Dried leaf. Cynaroside, chrysoeriol, Tomo34(1-2):7-365.2009 var. mendozana stomachic, cholagogue, hepatic luteolin: flavone Ajenjo blanco chico, ajenjo CAT, LRI, MEN, SJU Essential oil. Azulene: sesquiterpene; Barboza 944 (CORD) thujone: monoterpene Artemisia mendozana var. Aerial parts: hepatic, stomachic, No biological test No data paramilloënsis F. A. Roig & digestive Ambrosetti MEN Ajenjo Kurtz 10925 (CORD) Baccharis artemisioides Aerial parts: antirheumatic Aerial parts: cytotoxic effect Dried aerial parts. Bartemidiolide: Hook. & Arn. BAI, CAT, COR, COS, ERI, LPA, diterpene Romerillo blanco, pichana RNE, SFE, SLU, TUC Essential oil. Borneol, farnesol: blanca, romerillo malo, monoterpenes romerillo, mío-mío blanco Part not specified. Roridin D: Hunziker 8150 (CORD) sesquiterpene Baccharis articulata (Lam.) Aerial parts: hepatic, digestive, Dried aerial parts: bitter tasting Aerial parts. Articulin, articulin Pers. antiseptic, cholagogue, hepatotonic, effect; antiviral, anti- acetate: diterpenes; aromadendrene: Carquejilla, carqueja, antiulcer, antidiabetic, febrifuge, inflammatory and antioxidant sesquiterpene; luteolin, quercetin, carqueja blanca, carqueja anthelmintic, antidiarrheal, diuretic, activity cirsimaritin, salvigenin: flavonoids; crespa for treatment of wounds externally, genkwanin, acacetin: flavone; 7-4´- Ariza Espinar 1706 (CORD) impotence and female sterility, sexual dimetilapigenin; 4’-O-β-D- stimulant, and to treat urinary and glucopyranosyl-3’,5’-dimethoxy- respiratory tract infections, for benzylcaffeate: humoral and blood diseases; to treat derivative; caffeic acid, chlorogenic male impotence acid, 4,5-dicaffeoylquinic acid, 3,5- BAI, CAT, CHA, COR, COS, ERI, dicaffeoylquinic acid, 3,4- JUJ, LPA, LRI, MIS, SDE, SFE, dicaffeoylquinic acid SLU, TUC KURTZIANA

BARBOZA, G.E.etal.MedicinalfloraofArgentina Baccharis articulata (Lam.) Aerial parts essential oil. Camphene, Pers. Δ3–carene, trans-β-ocimene, γ- (continuation) cadinene, α-gurjunene, α-cadinol, α- calacorene, trans-calamenene, β- caryophyllene, α-cubebene, β- cubebene, cubenol, β-elemene, cis- β- farnesene, germacrene D, γ-gurjunene, α-humulene, limonene, α-copaene, globulol, epiglobulol, linalool, β- sesquiphellandrene, α-muurolene, γ- muurolene, T-muurolol, trans-nerolidol, β-pinene, spathulenol, terpinen-4-ol, terpinolene, α-terpineol, valencene, neral, caryophyllene oxide, δ-cadinene, α-pinene, myrcene, T-cadinol, β- guaiene aromadendrene, bicyclogermacrene; α-caryophyllene, epi-α-bisbaolol, γ-elemene Female plants essential oils. β-pinene, spathulenol, (E) nerolidol Male plants essential oil: spathulenol, β-caryophyllene, bicyclogermacrene, (E) nerolidol Flowers. Barticulidiol, bacchotricuneatin A: diterpenes Baccharis boliviensis (Wedd.) Aerial parts: vulnerary Dried aerial parts: alelopatic Aerial parts. 4,5-hydroxy-3,3,6,7,8- Cabrera var. boliviensis CAT, JUJ, SAL, TUC activity; trypanocidal effect pentamethoxyflavone, terprenes; Romero, chijua, chajhura, bolivianol: ent-clerodane chicha, chisqua, cosco, pesco furanoditerpenoid tola, sacha tola, tola, tola chijua Ariza Espinar 2723 (CORD)

107

Baccharis coridifolia DC. Aerial parts: to induce abortion, Aerial parts: antioxidant, Aerial parts essential oil. β- 108 Mío-mío, romerillo, ajenjo for treating wounds externally; antifungal, antiviral and caryophyllene, caryophyllene oxide: Tomo34(1-2):7-365.2009 del campo, mío, niyo disease in livestock, cytotoxic activity; toxicity to the sesquiterpenes Ariza Espinar 2268 (CORD) hepatoprotective, anti- brine shrimp Dried inflorescence + seeds. inflammatory Flower + fruit + leaf: Miophytocen b, miotoxin a, miotoxin b: BAI, CAT, CHA, COR, COS, ERI, anticrustacean activity misc lactone FOR, JUJ, LPA, LRI, MEN, MIS, Leaf + stem: cytotoxic activity Aerial parts (male plants). Miotoxin SAL, SDE, SFE, SJU, SLU, TUC C, roridin A, E: sesquiterpenoids Seed coat. Roridin A, E: sesquiterpenoid Aerial parts. Verrucarins, roridin, satratoxins, baccharinoids: macrocyclic trichothecenes Baccharis crispa Spreng. Aerial parts: diuretic, hepatic, Dried aerial parts: anti- Aerial parts. Apigenin,7-4’- Carqueja digestive, cholagogue, tonic, inflammatory, antioxidant, and dimethylapigenin, 3´-4´-7-tri-O-methyl- Ariza Espinar 2358 (CORD) antiulcer, antiseptic, anthelmintic, antibacterial, and antifungal luteolin: flavonoids; genkwanin, 3'-5- febrifuge, aphrodisiac, for treating activity dihydroxy-4'-7-dimethoxy flavone: wounds externally and impotence Dried root: antiviral activity flavones; bacrispine, 1-desoxy-bacrispine, and female sterility; for hair care hautriwaic acid: diterpenes; caffeic acid, (dandruff and seborrhoea) chlorogenic acid, 4,5-dicaffeoylquinic acid, BAI, CAT, CHU, COR, LPA, LRI, 3,5-dicaffeoylquinic acid, 3,4- MEN, RNE, SAL, SFE, SJU, SLU, dicaffeoylquinic acid TUC Dried aerial parts essential oil. α-pinene, β-pinene, α-thujene, camphene, sabinene, myrcene, α-phellandrene, p-cymene, limonene, trans-β-ocimene, γ-terpinolene, linalol, terpinen-4-ol, α-cubebene, β- cubenene, α-copaene, α-gurjunene, α and β-caryophyllene, aromadendrene, α- humulene, γ-muurolene, germacrene-D, bicyclogermacrene, α-elemene, γ-elemene, KURTZIANA α-selinene, α-muurolene, germacrene-A, γ- cadinene, δ-cadinene, β- sesquiphellandrene, caryophyllene oxide, ledol, globulol, epiglobulol, humulene oxide II, spathulenol, trans-nerolidol, 1-epi- cubenol, cedr-8(15)-en-9-α-ol, cubenol, α- cadinol, calamenenol

BARBOZA, G.E.etal.MedicinalfloraofArgentina Baccharis darwinii Hook. & Aerial parts: antimicrobial No biological test Dried aerial parts. Auraptene, 5'-oxo Arn. BAI, CAT, CHA, CHU, COR, auraptene: coumarin; β farnesene: Ariza Espinar 1920 (CORD) COS, ERI, FOR, LPA, LRI, MEN, sesquiterpene NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC Baccharis flabellata Hook. Essential oil: antimicrobial Plant essential oil: antibacterial Dried aerial parts. Baccharis diterpene & Arn. COR, LPA, LRI, SDE, SJU, SLU activity 1-A: diterpene; cirsiliol, hispidulin: Carqueja, charrúa, chilquilla, flavone; 2,19;15,16-diepoxy-neo- clavillo, romerillo clerodan-3,13(16),14-trien-18-oic acid, Ariza Espinar 2356 (CORD) 15,16-epoxy-5,10-seco-clerodan- 1(10),2,4,13(16),14-pentaen-18,19- olide, 15,16-epoxy-neo-clerodan- 1,3,13(16),14-tetraen-18,19-olide: diterpenoid derivatives

Baccharis gaudichaudiana Aerial parts: digestive, hepatic, Dried aerial parts: sweetening Dried aerial parts. Apigenin, DC. antidiabetic, antidiarrheal, to treat effect; antioxidant, quercetin-3-O-L-α-rhamnoside, rutin, Carqueja, chilca melosa urinary and respiratory tract antileishmanial and cytotoxic eupafolin: flavonoids; articulin acetate; Arbo 2308 (CORD) infections activity gaudichaudioside A, gaudichaudioside CHA, COS, MIS, SDE B, gaudichaudioside C to F: clerodane diterpenoids; bacchariol, 15,16.epoxy- 15α-methoxy-ent-clerod-3-en-18-oic acid, 13-epi-15,16-epoxy-15α-methoxy- ent-clerod-3-en-18-oic acid and 7-oxo- 16-hydroxy-ent-clerod-3-en-15-oic acid methyl ester-18,19-olide: ent-clerodane diterpenes; 3,5-dicaffeoylquinic acid: phenolic acid derivative Baccharis genistifolia DC. Entire plant: antispamodic No biological test No data Hunziker 2298 (CORD) BAI, CHU, COR, LPA, SFE Baccharis gilliesii A. Gray Flowers + leaf: antispamodic No biological test Aerial parts. 3,6,3’ Me Quercetagenin: Mata trigo, mata pulga BAI, CAT, CHA, CHU, COR, flavonoid Hunziker 4115 (CORD) COS, ERI, JUJ, LPA, LRI, MEN, RNE, SDE, SFE, SLU, TUC 109

Baccharis grisebachii Aerial parts: digestive and to Aerial parts: antimicrobial, Aerial parts. Pectolinaringenin: 10

Hieron. relieve gastric ulcers, antidiarrheal and antiulcer flavone; nevadensin, 5,7,4'-trihydroxy- Tomo34(1-2):7-365.2009 Tola alta, quinchamal, antirheumatic, antiseptic, activity; free radical scavengers 6-methoxyflavone, quercetin, 5,7,4'- kinchamiel, lancha, cicatrizant, and lipoperoxidation inhibition trihydroxy-6,3'-dimethoxyflavone, quinchamali, romerillo, Leaf: for wound healing in erythrocytes; toxicity to the 5,7,4'-trihydroxy-6,8- tancha CAT, JUJ, LRI, MEN, SAL, SJU, brine shrimp dimethoxyflavone: flavonoids; labda- Hunziker 1867 (CORD) TUC 7,13E-dien-2β,15-diol: labdane diterpene; drupanin, 4-acetyl-3,5- diprenylcinnamic acid and trans-ferulic acid O-hexan-3-onyl-ether, 4-acetyl-3- prenyl-ethoxycinnamate, 3-prenyl-4-(4'- hydroxydihydrocinnamoyloxy)- cinnamate: p-coumaric acid derivatives Baccharis latifolia (Ruiz & Leaf: for wound healing; for skin Plant essential oil: antibacterial Aerial parts essential oil. Germacrone-D, Pav.) Pers. infections and diabetes (sub nom. and anti-inflammatory activity α-thujene, α-pinene, limonene, ledol Chilca, niquitao B. floribunda) Aerial parts. 5-hydroxy-7,4´- Baccharis floribunda Kunth Leaf + stem, decoction: for dimethoxyflavone, 3,5,4´-trihydroxy- Zardini 1418 (LP) rheumatism, liver disease, wounds 7,3´dimethoxyflavone, 3,5-dihydroxy- and ulcers 5,7,3´,4´trimethoxyflavone, 3-hydroxy- CAT, JUJ, LRI, SAL, TUC 5,7,3’,4’tetramethoxyflavone, 5-hydroxy- 7.3’,4’ trimethoxyflavone: flavonoids Baccharis linearis (Ruiz & Ash: antirheumatic Aerial parts: alelopatic and Stem + leaf. Lachnophyllum ester, Pav.) Pers. Plant: mountain sickness cytotoxic activity spathulenol; werneriachromene, Romerillo CHU, MEN, NEU, RNE acetylated dihydrobenzofuran; Bernardello 584 (CORD) erythrodiol; oleanolic acid, drupanine; maslinic acid, 3-O- methylkaempferol, 3-O-methylquercetin, 3,3’-O- dimethylquercetin, jewenol A, diterpene acids; stigmasta-7,22-dien-3β-ol, stigmasta-7,22-dien-3β-ol-β-D- glucopyranoside, nepetin, quercetin 3-

methyl ether, lachnophyllum ester, KURTZIANA werneria chromene, portulide B, neo- clerodane type diterpenes and one perhydroazulene derivative Aerial parts essential oil. α- and β- pinene, myrcene, limonene, δ-cadinene, bicyclogermacrene, caryophyllene oxide, cubenol and α-cadinol

BARBOZA, G.E.etal.MedicinalfloraofArgentina Baccharis microcephala Aerial plant: hepatic, No biological test Dried aerial parts essential oil. α- (Less.) DC. antidiarrheal, cardioactive, copaene, β-elemene, α-humulene, β- Carqueja, carqueija diuretic, febrifuge, caryophyllene, allo-aromadendrene, γ- Schinini 19359 (CORD) BAI, CHA, COS, DFE, ERI, FOR, gujunene, α-himachalene, α-muurolene, MIS, SFE δ-cadinene, ledol, spathulenol, caryophyllene oxide, globulol, epiglobulol, tau-cadinol, α-cadinol Baccharis notosergila Griseb. Entire plant: antimicrobial, Dried aerial parts: antifungal Dried aerial parts. Apigenin, Carqueja antibiotic, antirheumatic, hepatic, and antibacterial activity genkwanin: flavone; caffeic acid, Ariza Espinar 1931 (CORD) diuretic, digestive, cholagogue, Dried root: antiviral activity chlorogenic acid, 4,5-dicaffeoylquinic febrifuge, antiseptic, antispasmodic Dried stem: antitrypanosomal acid, 3,5-dicaffeoylquinic acid, 3,4- BAI, CHA, COR, COS, ERI, FOR, activity dicaffeoylquinic acid SDE, SFE Baccharis obovata Hook. & Aerial plant: antispamodic, No biological test Aerial parts essential oil. α-thujene, α- Arn. against the alopecia and β-pinene, sabinene, myrcene, Huautro, chilca, romerillo, CHU, NEU, RNE, SCR limonene, terpinen-4-ol guantro, vatrú Cocucci 2138 (CORD) Baccharis oxyodonta DC. Part not specified: cicatrizant, No biological test Dried aerial parts essential oil . Sabinene, Tressens 6359 (CTES) maturating, for acne, hernia, β-pinene, myrcene, limonene, α-gurjunene, chilblain, and against the scabies β-caryophyllene, germacrene-D, MIS bicyclogermacrene, spathulenol, β- phellandrene, α-terpinolene, p-cymene, cis- sabinene hydrate Root. Pinocembrin, pinobanksin: Baccharis pingraea var. Aerial parts: antimicrobial, No biological test No data angustissima DC. antirheumatic, anti-inflammatory, Biurrun 5361 (CORD) antiseptic, astringent BAI, COR, ERI, LPA, LRI, MEN, RNE, SFE, SJU, SLU Baccharis pingraea DC. var. Entire plant: antimicrobial, Aerial parts: antimicrobial Aerial parts. Angeloyl-gutierrezianolic pingraea antirheumatic, anti-inflammatory, activity acid: furolabdane; furolabda-6,8-dien- Chilca, suncho astringent 17-oic acid, furolabda-7-en-17-oic acid: Ariza Espinar 2269 (CORD) BAI, CAT, CHA, CHU, COR, diterpenes; (10E) centipedic acid:

COS, DFE, ERI, FOR, JUJ, LPA, diterpenoid 111 LRI, MEN, MIS, NEU, RNE, SAL, SDE, SFE, SJU, SLU

112 Baccharis punctulata DC. Part not specified: for heart pains No biological test Dried aerial parts. Bicyclogermacrene, Tomo34(1-2):7-365.2009 Chilca BAI, CAT, CHA, COS, ERI, FOR, epi cubenol, germacrene D, α- Nicora 5896 (LP) JUJ, MIS, SFE, TUC humulene: sesquiterpenes Baccharis racemosa (Ruiz & Aerial parts: medicinal No biological test Aerial parts essential oil. Sabinene, β- Pav.) DC. CHU, NEU, RNE pinene, myrcene, limonene, δ-cadinene, Huautro, guodicoy nerolidol, viridiflorol, α-muurolol, α- Diem 1793 (SI) cadinol Baccharis rhomboidalis J. Ash: antirheumatic Dried aerial parts:β- Dried aerial parts. Baccharis diterpene Rémy NEU, RNE glucuronidase inhibition 3, baccharis diterpene 4: diterpenes; Cocucci 3480 (CORD) oleanolic acid: triterpene; 5-OH-7,4’- OMe-flavone Dried leaf. Acacetin: flavone; brein: triterpene Baccharis rufescens Spreng. Leaf: vaginal mycosis, anuria, urin Dried aerial parts: anti- Aerial parts essential oil. α-thujene, α- var. rufescens with blood inflammatory activity pinene, camphene, sabinene, myrcene, Δ3– Chilca roja BAI, CAT, CHA, COR, COS, ERI, Dried leaf: antiamebic activity carene, α-terpinene, limonene, γ-terpinene, Barboza 1228 (CORD) JUJ, LPA, LRI, MEN, MIS, RNE, terpinolene, linalool, terpinen-4-ol, α- SAL, SFE, SJU, SLU terpineol, neral, α-cubebene, trans-β- ocimene, α-copaene, β-cubebene, β- elemene, α-gurjunene, β-caryophyllene, aromadendrene, α-humulene, cis- β- farnesene, γ-muurolene, germacrene D, valencene, bicyclogermacrene, α- muurolene, γ-cadinene, δ-cadinene, β- sesquiphellandrene, trans-calamenene, α- calacorene, trans-nerolidol, spathulenol, caryophyllene oxide, T-cadinol, T- muurolol, cubenol, α-cadinol, epi-α- bisbaolol Aerial parts. Ent-3,19-disuccinyloxy- KURTZIANA kaur-16-ene: diterpene; oleanolic acid: triterpenoid; cirsimaritin (5,4’- dihydroxy-6,7-dimethoxyflavone), cirsiliol (5,3’,4’-trihydroxy-6,7- dimethoxyflavone): flavonoids

BARBOZA, G.E.etal.MedicinalfloraofArgentina Baccharis sagittalis (Less.) Aerial parts: digestive, hepatic, Aerial parts: antimicrobial Aerial parts. Marrubiagenin, cis- DC. tonic, cicatrizant, diuretic, activity cleroda-15,16-dihydroxy-3,13 (Z)-dien- Carqueja antidiarrheal, cardioactive 18-(β-D-galactopyranosil)- Giraldez 145 (CORD) CHU, MEN, NEU, RNE, SJU peracetylester; cis-cleroda-3,13 (14)- dien-15,16-olid-18-(β-D- galactopyranosil)-peracetylester: diterpenes Baccharis salicifolia (Ruiz & Aerial parts: antirheumatic, anti- Aerial parts essential oil: Dried aerial parts. Baccharis diterpene 10 Pav.) Pers. inflammatory, antiseptic, insecticide activity , baccharis diterpene 11, bacchasalicylic Chilca amarga, chilca, chilca astringent, febrifuge, diuretic, Fresh plant juice: acid: diterpenes; friedoolean-3β-ol, blanca, junco, t’ola alta, vermifuge; for stomachache, antimycobacterial activity stigmasterol, baccharis oxide chilca dulce, jarilla, jarilla del dysentery, and diarrhea; Aerial parts: antileishmanial Resin. Acacetin, apigenin: flavones río, junco, romerillo, suncho, gynecological and digestive activity Dried aerial parts essential oil. α-pinene, vara dulce, chillca, chirca, disorders, for skin diseases (sub β-pinene, α-thujene, camphene, sabinene, Baccharis glutinosa Pers. nom. B. glutinosa) myrcene, α-phellandrene, p-cymene, Hunziker 15929 (CORD) BAI, CAT, CHA, CHU, COR, COS, limonene, trans-β-ocimene, γ-terpinolene, DFE, ERI, FOR, JUJ, LPA, LRI, linalool, terpinen-4-ol, δ-elemene, β- MEN, MIS, NEU, RNE, SAL, SCR, elemene, α-cubebene, β-cubenene, α- SDE, SFE, SJU, SLU, TUC copaene, α-gurjunene, α and β- caryophyllene, aromadendrene, α- humulene, γ-muurolene, germacrene-D, bicyclogermacrene, α-selinene, γ-cadinene, δ-cadinene, β-sesquiphellandrene, α- calacorene, calamenene, caryophyllene oxide, T-cadinol, spathulenol, trans- nerolidol, cubenol, α-cadinol, verboccidentafuran Baccharis scandens (Ruiz & Aerial parts: calmative Aerial parts: anti-inflammatory Aerial parts. Bacchascandone: Pav.) Pers. (sub nom. B. calliprinos) activity norsesquiterpenoid; bacchalineol Chilca dulce, chascoma, CAT, LRI, MEN, SJU, TUC (sub nom. B. calliprinos) malonate: diterpenoid chilca, fia m ate, palo blanco, suncho blanco Baccharis calliprinos Griseb. Hunziker et al. 14246 (CORD) 113

Baccharis sculpta Griseb. Leaf: vaginal mycosis, anuria, urin No biological test No data 114

Chilca hoja larga, chilca troja with blood, diuretic Tomo34(1-2):7-365.2009 Hunziker 20413 (CORD) CAT, JUJ, LRI, SAL, TUC Baccharis sessiliflora Vahl Aerial parts: antiinflammatory Aerial parts: antioxidant Aerial parts essential oil. α-thujene, α- Baccharis cordobensis Heering BAI, CHA, COR, COS, ERI, LPA, activity pinene, camphene, sabinene, α- Hunziker 15933 (CORD) SFE phellandrene, limonene, terpinolene, linalool, terpinen-4-ol, α-terpineol, neral, α-cubebene, α-copaene, β-pinene, myrcene, β-elemene, α-gurjunene, α- humulene, α-cadinol, β-caryophyllene, aromadendrene, γ-muurolene, germacrene D, bicyclogermacrene, γ- cadinene, γ-cadinol, δ-cadinene, sesquiphellandrene, trans-nerolidol, T- cadinol, cubenol, spathulenol, caryophyllene oxide, (sub nom. B. cordobensis) Baccharis spartioides (Hook.. Entire plant: aromatic, to treat Entire plant: antipyretic and Dried aerial parts. Spartidienedione: & Arn. ex DC.) J. Rémy wounds, anti-inflammatory, anti-inflammatory activity sesquiterpene Pichana, pichana amarga, vermifuge, escoba, pichona BAI, CAT, CHU, COR, JUJ, LPA, Hunziker 9172 (CORD) LRI, MEN, NEU, RNE, SAL, SCR, SJU, SLU, TUC Baccharis spicata (Lam.) Aerial parts + root: medicinal Aerial parts: trypanocidal Dried aerial parts. Bacchotricuneatin Baill. BAI, CHA, COR, COS, DFE, ERI, activity A: diterpene Carqueja, chilca blanca FOR, LPA, SDE, SFE Hunziker 3637 (CORD) Baccharis tola Phil. Leaf: for wound healing Aerial parts: antileishmanial Aerial parts. 5,4’-dihydroxy- Lejía, legía fina, ligia, ñaca Part not specified: antirheumatic and antioxidant activity 3,6,7,8,3’-pentamethoxyflavone, 5,4’-

tola, pampa tola, tola, tola CAT, JUJ, LRI, MEN, SAL, SJU, dihydroxy-6,7,8,3’- KURTZIANA lejía, tola léjia, tola ñaca, tola TUC tetramethoxyflavone: flavonoids; yoque bincantriol, ent-beyerene-18,19-diol, Baccharis incarum Wedd. ent-beyeren-18-ol, 8,13-epoxy-14- Hunziker 23928 (CORD) labden-19-ol, neohibaenol: diterpenoids; oleanolic acid, β-amyrin, spathunelol; bacchalineol, barticulidiol, bicantriol

BARBOZA, G.E.etal.MedicinalfloraofArgentina Baccharis triangularis Aerial parts: hepatic, diuretic, No biological test Aerial parts. Luteolin, 7-O-metil Hauman cholagogue luteolin: flavones; ent-cleroda-3-em- Carqueja BAI, CHU, LPA, RNE, SLU 15,16,18,19-diolid: diterpene. Anderson 4067 (CORD) Baccharis trimera (Less.) Aerial parts: gastrointestinal Aerial parts + seeds: Aerial parts. Hautriwaic acid, 1-desoxy- DC. disorders, digestive, cholagogue, antimicrobial, antiviral, bacrispine, bacrispine, 7-4´-di-O-methyl- Carqueja, carqueja crespa, hepatic, analgesic, antiseptic, analgesic, bactericidal, anti- apigenin: diterpenes; apigenin, cirsimaritin, carqueja amargosa antirheumatic, tonic, febrifuge, leishmanial, diuretic, genkwanin, eupatorin, escoparol; luteolin, Hunziker 748 (CORD) anti-ulcer, anti-diabetic, diuretic, antioxidant, anti-mutagenic, nepetin; quercetin, hispidulin, rutin, for male impotence and female hypoglycemic, anti-ulcer, dilactone A, B, and C: flavonoids sterility, anthelmintic, anti- antirheumatic, relaxant, anti- Dried aerial parts essential oil. Carquejol, inflammatory, abortive, inflammatory, gastro-protective, α-pinene, sabinene, β-pinene, myrcene, emmenagogue, neonatal and antidiarrheal, and hepato- limonene, trans-β-ocimene,γ-terpinene, paediatrics care, used in pregnancy protective activity; embryotoxic naphtalen, α-terpinol, carquejil acetate, α- and facilitate birth, post partum and fetotoxic activity in rats cubebene, α-copaene, β-cubebene, α- pains and diseases elemene, β-elemene, γ-elemene, α- BAI, COS, ERI, JUJ, LPA, MIS, gurjunene, β-caryophyllene, β-gurjunene, SAL, SFE α-guaien,α-humulene, allo-aromadendrene, γ-gurjunene, γ-muurolene, γ-himachelene, β-selinene, valencene, viridiflorene, α-selinene, α-longipinene, α-muurolene, α-farnesene, germacrene-D, bicyclogermacrene, germacrene-B, aromadendrene, α-bisabolene, γ-cadinene, δ-cadinene, α-calacorene, γ-elemene, elemol, ledol, globulol, epiglobulol, humulene oxide I, spathulenol, caryophyllene oxide, guaien-4-ol, 1-epi- cubenol, γ-eudesmol, τ-cadinol, τ-muurolol, torreiol, β-eudesmol, α-eudesmol, α-cadinol, op lopanone, ph ytol, β-phellandrene, terpinolene, palustrol 115

116 Baccharis trinervis Pers. Leaf + shoot, infusion: digestive, Dried entire plant: superoxide Dried aerial parts. Acacetin, apigenin: Carqueja, chilca diuretic, lactogen, for vertigo, scavenging activity increase; flavone; β-amyrin, lupeol: triterpenes; Tomo34(1-2):7-365.2009 Novara 8015 (CORD) gastrointestinal disorders and fever antiviral activity; cytotoxic methyltrineracetal, epi- Dried leaf + stem, decoction: effect methyltrineracetal, deoxy articulin: digestive; for high fever, edema, Dried shoots: molluscicidal diterpenoids; 2'-4'-6'-trihydroxy sores, muscle cramps, dental, and activity chalcone: flavonoid urinary tract problems Plant essential oil: antifungal Dried leaf . 3'-5-dihydroxy-4'-7- CHA, COS, FOR, JUJ, MIS, SAL, and antibacterial activity dimethoxy flavone. SDE Dried branches. Pectolinaringenin, salvigenin: flavones; pedunletin: flavonol Aerial parts essential oil. α-thujene, α- and β-pinene, sabinene, β-phellandrene, (E)-lachnophyllum acid methyl ester, (Z)-lachnophyllum acid methyl ester Baccharis tucumanensis Aerial parts: abortive Aerial part: toxicity to the brine Aerial part. Batudioic acid: labdane Hook. & Arn. var. CAT, JUJ, SAL, TUC shrimp type diterpene; xanthomicrol, tucumanensis scutellarein-7,4′-dimethyl ether Suncho blanco, chilca Cabrera 3128 (LP) Baccharis vulneraria Baker Part not specified: antiseptic, for No biological test No data Hunziker 6526 (CORD) wounds Baccharidastrum BAI, CHA, COS, ERI, MIS, SFE triplinervium (Less.) Cabrera Bidens andicola var. cos- Root: for hepatic affections, anti- Aerial parts: antioxidant Aerial parts. 7-O-glycosides flavonols, mantha (Griseb.) Sherff emetic, stomachic activity β-D-glucopyranose, α-L- Saetilla, amor seco, michay, CAT, JUJ, SAL (sub nom. B. andicola) rhamnopyranose, β-D-xylopyranose, pante amarillo chalcone ester glycoside, chalcone Solís Neffa 855 (CTES) ester glycosides KURTZIANA (sub nom. B. andicola)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Bidens pilosa L. var. pilosa Entire plant: hypoglycemic, Dried aerial parts: Dried entire plant. Amor seco, saetilla, picón against toothache, icteric, radioprotective effect, Aesculetin:coumarin; β-amyrin, Ariza Espinar 1855 (CORD) febrifuge, cicatrizant, anti- antimalarial, antibacterial, phytosterin-β,esculetin,β-sitosterol inflammatory, diuretic, and against antimycotic, antihyperglycemic glucoside, lupeol,lupeol acetate; cough, blennorrhea, hepatic and and antihypertensive activity; T astragalin: flavonol; β-D- urinary ailments cell modulator glucopyranosyloxy-3-hydroxy-6(E)- Leaf: anti-ulcer, anti-emetic, Dried leaf: antibacterial and tetradecen-8,10,12-triyne; cytopiloyne hepatic, digestive, anti-ashmatic, anti-inflammatory activity (2β-d-glucopyranosyloxy-1- abortifacient hydroxytrideca-5,7,9,11-tetrayne), 5-O- Dried flowers: antidiarrheal . methylhoslundin; tridecapentyn-1- BAI, CHA, COR, COS, ERI, FOR, ene,trideca-2,12-diene-4,6,8,10- JUJ, MIS, SAL, SDE, TUC tetrayne-1-ol, trideca-3,11-diene-5,7,9- triyne-1,2-diol and trideca-5-ene- 7,9,11-triyne-3-ol Fresh leaf. 3'-4'-6-7-tetrahydroxy -cis 7-O-β-D- glucopyranoside : flavonoid Leaf essential oil. α- and β-pinene, limonene, β-phellandrene, thymol, β- copaene, β-guaien, β-humulene, cadinene, β-bisabolene, α-farnesene, β caryophyllene: terpenoids; 1-phenyl- hepta-1-3-5-triyne: benzenoid Bidens subalternans var. Aerial parts: ophtalmic, digestive Dried entire plant: anti- Dried entire plant. Maslinic acid: simulans Sherff BAI, CAT, COR, COS, ERI, JUJ, inflammatory and antibacterial triterpene; stigmasterol: steroid Amor seco, saetilla LPA, MIS, SDE, SFE, SJU, SLU, activity Cantino 699 (CORD) TUC Chaetanthera pulvinata Dried aerial parts, infusion: for No biological test No data (Phil.) Hauman altitude sickness Escarapela, flor de la puna CAT, MEN, SJU, TUC Hunziker 20852 (CORD) Chaetanthera sphaeroidalis Dried aerial parts: antitussive, for No biological test No data (Reiche) Hicken altitude sickness Flor de puna, poposa LRI, SJU Bustos s.n. (CORD) 117

118 Chaptalia integerrima Part not specified: astringent, No biological test Dried aerial parts. 7-hydroxy (Vell.) Burkart vulnerary coumarin,8-0-β-D-glucoside: coumarin Tomo34(1-2):7-365.2009 Lengua de vaca, pilosilla BAI, CAT, CHA, COR, COS, ERI, Ariza Espinar 2239 (CORD) JUJ, LPA, LRI, MIS, SAL, SFE, SJU, SLU, TUC Chaptalia nutans (L.) Pol. Entire plant: pectoral, against Dried leaf: anti-inflammatory, Dried root. Nutanocoumarin; 7-O-b-D- Cerraja, pelusa catarrh, antifebril, astringent, anti-edematogenic (edema glucopyranosyl-nutanocoumarin; Ariza Espinar 1977 (CORD) vulnerary, decongestant, induced by snakebit), and prunasin: benzenoid ophthalmic, anti-depressive antibacterial activity Dried root, infusion: for fever, Root: antibacterial activity skin disease, and syphilis Leaf, infusion: for amenorrhea, laxant, bequic, for skin infections BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Chaptalia piloselloides Part not specified: astringent, No biological test No data (Vahl) Baker vulnerary Meyer 2287 (LP) BAI, COS, ERI, LPA, MIS Chaptalia sinuata (Less.) Entire plant: pectoral, against No biological test No data Baker catarrh, febrifuge, astringent, Yerba de San Juan vulnerary, decongestant, ophtalmic Ariza Espinar 1693 (CORD) BAI, CAT, CHA, COR, COS, ERI, JUJ, LPA, MIS, SAL, SFE, SJU, SLU, TUC Chersodoma argentina Dried aerial parts, infusion: for No biological test Essential oil. Iso valeric acid Cabrera nervous diseases Tola gris, salvia de la puna, Leaf: vulnerary salvia blanca, tola blanca, CAT, JUJ, LRI, SAL, TUC quinchamal, tola de burro KURTZIANA Hunziker 19217 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Chersodoma jodopappa Medicinal Dried leaf + stem: Dried aerial parts. Senkirkine: (Sch. Bip. ex Wedd.) Cabrera CAT, JUJ, LRI, SAL, TUC antitrypanosomal and secopyrrolizidine alkaloid; 6β -hydroxy- Salvia de la lu na, salvia de la antileishmanial activity 8β[H)-eremophila-7 (11)-en- 8,12-olide puna, tola, tola de burro (6β-hydroxyeremophilanolide),6β, 8β- Núñez 556 (CORD) dihydroxy- 10 β [H]-eremophila-7 (11)-en- 8,12-olide (6β, 8β- dihydroxyeremophilanolide): sesquiterpene lactones of the eremophilanolide type Chiliophyllum densifolium Aerial parts: diuretic, hepatic, for No biological test No data Phil. sandstone in kidneys and liver Romero pichi, romero del MEN piche, romero chico, piche Hunziker 23678 (CORD) Chiliotrichum diffusum (G. Flowers: eyes disease Leaf + flowers: antioxidant Flowers. ; 3,7,4’- Forst.) Kuntze MEN, NEU, RNE activity trihydroxy-flavylium, apigeninidin: Mata negra, Ko’or, Kóor, Flowers: antinociceptive and tannin incienso, fachine, margarita, anti-inflammatory activity romerillo Grondona 7119 (BAA) Chuquiraga acanthophylla Leaf + spines: antitussive No biological test No data Wedd. JUJ Espina amarilla, planta de San Pedro Novara 8251 (CORD) Chuquiraga avellanedae Aerial parts: antitussive No biological test Dried aerial parts. Lupeol, 6-β- Lorentz CHU, MEN, NEU, RNE, SCR hydroxy taraxast-20-ene: triterpene Mataquerosén, quilembay, calembay, trayao lahuén Cocucci 2530 (CORD) Chrysanthellum indicum Aerial parts: antiseptic, Aerial parts: antioxidant Aerial parts. Flavonoids, saponnins, subsp. afroamericanum B.L. antispasmodic, topical agent for activity; effective anti- phenylpropenoic acids (sub nom. C. Turner the treatment of moderate rosacea inflammatory agent indicum) Crisalina (sub nom. C. indicum) (sub nom. C. indicum)

Hunziker 12165 (CORD) CAT, COR, COS, JUJ, LRI, SAL, 119 SDE, SFE, SLU, TUC

120 Cnicothamnus lorentzii Medicinal Leaf + stem: antileishmanial No data Tomo34(1-2):7-365.2009 Griseb. JUJ, SAL, TUC activity Azafrán Cabrera 22576 (LP) Conyza bonariensis (L.) Aerial parts: antiulcer, hepatic, Aerial parts essential oil : Dried aerial parts. Acacetin, takakin- Cronquist abluent, anthelmintic, cicatrizant; anti-inflammatory activity, 8-O-glucoronide: flavones; β-pinene, Hierba carnicera, yerba infusion: antipyretic, xanthine oxidase inhibition, myrcene, dl- limonene, (Z)-β – carnicera, rama negra, vira antirheumatic, for stomach ulcers, inotropic effect positive, CNS ocimene, (E)-β – ocimene, p- Mentha- vira, mata negra, melena de diuretic, antiseptic, urinary, depressant and cardiotonic 1,5,8-triene, p- Mentha-1,3,8-triene: viejo antidiarrheal, cicatrizant, for acne activity monoterpenes; amyrin: triterpene; Hunziker 8095 (CORD) and gastritis ambrosin, coronopilin, BAI, CAT, CHA, COR, COS, ERI, bicyclogermacrene, trans β farnesene, JUJ, LPA, LRI, MEN, MIS, NEU, α-humulene, β-farnese, germacrene D, RNE, SAL, SDE, SFE, SJU, TUC δ-cadinene, trans-nerolidol, spathulenol, caryophyllene oxide, humulene epoxide, epi-α-muurolol, α-cadinol: sesquiterpenes; chlorogenic acid: phenylpropanoid; iso quercitrin: flavonol Conyza sumatrensis (Retz.) Aerial parts: antitussive, pectoral Dried entire plant: insecticide Dried aerial parts. Caryophyllene E. Walker var. sumatrensis Dried leaf, decoction: for malaria activity oxide, β-farnesene: sesquiterpenes Ariza Espinar 1857 (CORD) BAI, CAT, CHA, COR, COS, ERI, Stem: antibacterial activity Aerial parts essential oil. α and β- JUJ, LPA, LRI, MIS, SAL, SFE, Flowers + fruits: antibacterial pinene, myrcene, sabinene, dl- SLU, TUC and antifungal activity limonene, (Z)-β – ocimene, (E)-β – ocimene, p- Mentha- 1,5,8-triene, p- Mentha- 1,3,8-triene: monoterpenes; (E)-caryophyllene, α-humulene, β- farnese, germacrene D, bicyclogermacrene, δ-cadinene, trans- KURTZIANA nerolidol, germacrene D-4-ol, spathulenol, caryophyllene oxide, epi- α-muurolol, α-cadinol: sesquiterpenes

Conyza sumatrensis var. Part not specified: cicatrizant, to Part not specified: antiviral and Leaf. Decahydro- 1, 1,7-trimethyl-4- BARBOZA, G.E.etal.MedicinalfloraofArgentina leiotheca (S.F. Blake) Pruski relieve the lumbago (sub nom. C. anti-inflammatory activity (sub methylene 1 H-cycloprop(e) azule-7-ol, & G. Sancho floribunda) nom. C. floribunda) 24-Ethyl chrolesta-5,22-diene-3-ol (sub Conyza floribunda Kunth BAI, CAT, CHU, COR, COS, ERI, nom. C. floribunda) Conyza sumatrensis var. JUJ, LPA, LRI, MEN, MIS, NEU, Aerial parts essential oil. α and β- floribunda (Kunth) J. B. RNE, SAL, SCR, SFE, TUC pinene, myrcene, dl- limonene, (Z)-β – Marshall ocimene, (E)-β – ocimene: Hunziker 8704 (CORD) monoterpenes; (E)-caryophyllene, α- humulene, β-farnese, germacrene D, bicyclogermacrene, trans-nerolidol, spathulenol, caryophyllene oxide, epi- α-muurolol, α-cadinol: sesquiterpenes (sub nom. C. sumatrensis var. floribunda) Cosmos peucedanifolius Leaf + stem, infusion: antipyretic, No biological test No data Wedd. antitussive Barboza 310 (CORD) Leaf: diaphoretic JUJ, SAL, TUC Cyclolepis genistoides D. Aerial parts, decoction: diuretic, Aerial parts: diuretic effect; Flower + leaf. β-amyrin: triterpene; Don antirheumatic, antitussive, for anti-inflammatroy activity deacyl cynaropicrin,: sesquiterpene Palo azu l, m atorro, azu squi, treatment of renal and hepatic Aerial parts. 12 α,13 α-epoxyoleanolic matorro negro, monte azul colics acid, 3 β,30-dihydroxylup-20(29)-ene, Hunziker 17484 (CORD) BAI, CAT, COR, LPA, LRI, 28-dihydroxylup 20(29)-en-30-al, MEN, NEU, RNE, SAL, SFE, deacylcynaropicrin, dihydroeleganin, SJU, SLU, TUC isolippidiol Dasyphyllum diacanthoides Aerial parts: antitussive, Aerial parts: antibacterial Dried aerial parts. Lupeol, lupeol (Less.) Cabrera antiseptic, vulnerary, antifeverish activity acetate: triterpenes Palo santo, palo blanco, tayú, CHU, NEU, RNE palo santo del sur, trevo, arrayán Belgrano 138 (SI) Dinoseris salicifolia Griseb. Medicinal No biological test Aerial parts. Heptadeca-trans-2-trans- Hunziker 19465 (CORD) CAT, CHA, JUJ, SAL, TUC 8-trans-10-16-tetraene-3-6-diyn-1-ol: alkenyne C5 or more; ivangustin,5-6- dehydro: sesquiterpene

Root. Ivangustin,5-6-dehydro: 12 sesquiterpene; trideca-1-trans-11-diene- 3-5-7-9-tetrayne: alkenyne C5 or more

122 Dolichlasium lagascae D. Part not specified: diuretic, Dried entire plant: Dried root. Caffeic acid: Don antitussive, against the influenza, antibacterial activity phenylpropanoid; dolichlasin: Tomo34(1-2):7-365.2009 Yerba del ciervo emmenagogue, pectoral sesquiterpene; pereflorin,3-4-8- Chiarini (CORD) LPA, LRI, MEN, NEU, SJU trimethoxy: coumarin; iso sakuranetin: Eclipta prostrata (L.) L. Part not specified: astringent, cic- Plant: antioxidant, Aerial parts. Nicotine: pyridine Eclipta alba (L.) Hassk. atrizant, hemostatic, for arthritis antihemorrhagic, alkaloid; flavonoids, triterpenes, Hunziker 11026 (CORD) rheumatoid, anti-hepatotoxic, anti- anti-inflammatory, anti- ; wedelolactone: hipertensive, antitumoral and hepatotoxic activity and in the coumestans (sub nom. E. alba) antiophidic effects hepatic infections Root. Demethylwedelolactone: BAI, CAT, CHA, COR, COS, ERI, (sub nom. E. alba); giardicidal coumestans FOR, JUJ, LRI, MIS, SAL, SDE, activity SFE, SJU, TUC Egletes viscosa (L.) Less. Leaf: digestive, anti-disentery Flower essential oil: analgesic Dried flower buds. Centipedic acid, Hunziker 6664 (CORD) CHA, COS, FOR, SAL activity 12-acetoxy hautriwaic acid lactone: diterpenes; ternatin: flavonol Elephantopus mollis Kunth Dried aerial parts, infusion: Entire plant: cytotoxic and Dried entire plant. β-amyrin acetate: Lengua de vaca febrifuge, diuretic; decoction: anti-inflammatory activity triterpene; molephantinin, deoxy Hunziker 18730 (CORD) antibacterial agent, antiviral, elephantopin: sesquiterpenes; epi antipyretic, and for rheumatism friedelinol, lupeol: triterpene Fresh leaf + root, decoction: febrifuge Part not specified: astringent, bitter tonic CAT, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Erechtites hieracifolius var. Part not specified: antimicrobial ; for No biological test Part not specified. Hieracifoline: cacalioides (Fisch. ex catarrhal states and passive pyrrolizidine alkaloid Spreng.) Griseb. hemorrhages and swelling of the feet Aerial parts essential oil. α-pinene, Ariza Espinar 790 (CORD) BAI, CHA, COR, COS, DFE, ERI, myrcene, (E)-β -ocimene, (E)- FOR, JUJ, MIS, SAL, SFE, TUC caryophyllene, germacrene D, sabinene, KURTZIANA β-pinene, limonene, linalool (sub nom. E. hieracifolia) Eupatorium argentinum Medicinal No biological test Leaf essential oil. p-cimene, α-pinene: Ariza CAT, CHA, COR, JUJ, MIS, SAL, monoterpenes Ariza Espinar 2353 (CORD) SLU, TUC

Eupatorium arnottianum Aerial parts: antispamodic, expec- Dried aerial parts: analgesic, Plant. Nepetin, jaceosidin, hispidulin, BARBOZA, G.E.etal.MedicinalfloraofArgentina Griseb. torant, to relieve the stomach-ache, anti-inflammatory, antibacterial , hyperoside, rutin, caffeic Clavel, tují for asthm, colds, bronchitis, activity; cell proliferation and chlorogenic acids Ariza Espinar 2230 (CORD) gastrointestinal pain, and topically inhibition; immunomodulating in plasters for bone fractures properties CAT, CHA, COR, COS, ERI, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Eupatorium artemisiifolium Aerial parts: bitter tonic No biological test No data Griseb. BAI, COR, ERI Ariza Espinar 1552 (CORD) Eupatorium buniifolium Aerial parts: bitter tonic, Aerial parts: antiviral, Dried aerial parts. Acacetin, Hook. & Arn. var. buniifolium disinfectant, hepatoprotective trypanocidal, leishmanicidal, , jaceidin: flavones; β amyrin: Chilca, mio-mio, romerillo, BAI, CAT, COR, ERI, JUJ, LPA, anti-inflammatory, and triterpene; hispidulin, : flavonoids; romero LRI, MEN, SAL, SJU, SLU, TUC antioxidant activity; 5,7,5'-trihydroxy-3,6,2',4'- Ariza Espinar 1356 (CORD) immunomodulating properties; tetramethoxyflavone, scopoletin, DNA polymerase and cell centaureidin; methyl-ent-labd-8(17)-en- proliferation inhibition 18-oic acid-15-oate, 15-hydroxy-ent-labd- 8(17)-en-18-oic acid, 15,16-epoxy-15- methoxy-ent-labd-8(17)-en-18-oic acid, 15-methoxy-ent-labd-8(17)-13-dien-18- oic acid methyl ester-16,15-olide, polyalthic acid, nivenolide: ent-labdanes Eupatorium bupleurifolium Aerial parts: menstrual diseases, No biological test Aerial parts. Limonene, α-pinene, β- DC. to expel the placenta and as pinene: monoterpenes Prementina protective post partum Hunziker 21625 (CORD) BAI, CAT, CHA, COS, ERI, JUJ, MIS, SAL, TUC Eupatorium candolleanum Aerial parts: laxative Dried entire plant: antibacterial No data Hook. & Arn. BAI, CHA, COR, COS, ERI, FOR, activity Tabaco del monte MIS, SFE Hunziker 16823 (CORD) Eupatorium catarium Medicinal No biological test Fresh root. Heliotridine,7-angeloyl, Veldkamp CAT, CHA, COR, COS, ERI, intermedine, trachelanthamine, Eupatorium clematideum FOR, JUJ, MIS, SAL, SDE, SFE, rinderine, supinine: pyrrolizidine Griseb. SLU, TUC alkaloids (sub nom. E. clematideum) 123 Ariza Espinar 1849 (CORD)

124

Eupatorium ceratophyllum Aerial parts: digestive, febrifuge, No biological test No data Tomo34(1-2):7-365.2009 Hook. & Arn. hepatic Caro 3437 (CORD) CHA, COR, ERI, SFE Eupatorium christieanum Aerial parts: analgesic, febrifuge, Dried aerial parts: analgesic No data Baker anticephalalgic, for pains and renal and antibacterial activity; cell Doctorcito, hoja de la virgen affections, colds, and for the proliferation inhibition Hunziker 5490 (CORD) treatment of gastrointestinal and viral diseases Root: antinephritic CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE Eupatorium hecatanthum Aerial parts: antitussive, Dried aerial parts: antibacterial Leaf essential oil. α-Pinene, p-thymyl (DC.) Baker digestive, gastrointestinal diseases, and cytotoxic activity; toxicity to acetate, p-cymene, Hunziker 917 (CORD) analgesic, antidiarrheal the brine shrimp BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC Eupatorium hookerianum Medicinal No biological test Aerial parts. Acacetin, apigenin 7- Griseb. CAT, COR, JUJ, SAL, TUC rhamnoside, kaempferitrin, kaempferol Hediondilla negra 3-glucoside-7-rhamnoside, kaempferol Ariza Espinar 3648 (CORD) 7-rhamnoside: flavonoids. Eupatorium inulifolium Aerial parts: contraceptive, Aerial parts: antimicrobial Aerial parts. Diterpenes Kunth emmenagogue, abortive activity Leaf. Guajaverin (3-O-L- Dotorcito BAI, CAT, CHA, COR, COS, ERI, Leaf: antioxidant activity arabinosylquercetin): flavonoid Barboza 918 (CORD) FOR, JUJ, MIS, SAL, SFE, TUC Eupatorium laevigatum Aerial parts: emmenagogue, Dried aerial parts: analgesic, Aerial parts. Laevigatin: Lam. analgesic, anticefelalgic, cathartic, antioxidant, antifungal, norsesquiterpenoid; germacrene D,

Dotorcito, sanatodo purgative, abortifacient antibacterial, nematicidal, and bicyclogermacrene KURTZIANA Ariza Espinar 256 (CORD) Entire plant, infusion: cytotoxic activity abortifacient; decoction: for aches BAI, CHA, COS, ERI, FOR, JUJ, MIS, SFE, TUC

Eupatorium Aerial parts: digestive, hepatic, Aerial plant essential oil: Aerial parts. 7-methoxy BARBOZA, G.E.etal.MedicinalfloraofArgentina macrocephalum Less. emmenagogue, abortifacient, antibacterial and antioxidant : flavonoid; coumarin; Teyú caá, teyú-igsipó, illa antitussive and for sore throat activity rhamnocitrin: flavonol; triterpenes, ka’ik, lankú kachú Flowers: for sore throat diterpene glycoside ester, steroids, Ariza Espinar 2166 (CORD) BAI, CHA, COR, COS, ERI, FOR, cinnamic acids derivatives; cirsilol: JUJ, MIS, SAL, SDE, SFE, TUC flavonoid Leaf essential oil. β-caryophyllene, germacrene D Leaf + inflorescence essential oil. Hexadecanoic acid, β-caryophyllene, germacrene D, geranyl acetate Eupatorium odoratum L. Part not specified: tonic No biological test Leaf. 2’,3’,4,4’,6’- Saravia Toledo 2124 (CORD) COS, FOR, JUJ, MIS, SAL, TUC pentahydroxychalcone: chalcone; epoxylupeol: triterpenoid; salvigenin; p- anisic acid Eupatorium patens D. Don Whole plant (burnt over charcoal): Leaf: antimicrobial activity Leaf. (E)-caryophyllene, α-muurolene, α- ex Hook. & Arn. var. patens for fever and β-pinene, sabinene, β-myrcene, Δ-2 Acacia del campo, crucecilla, BAI, CAT, CHU, ERI, JUJ, LPA, carene, α-thujene, Δ-2- ortho-cimene, acancio, bejuco, clavel LRI, MEN, NEU, RNE, SAL, SJU, limonene, (Z)-β-ocimene, terpinene, Hunziker 23663 (CORD) SLU, TUC perylene, terpinen-4-ol , β-elemene, (Z)-α- bergamotene, α-santalene, elemene, Epi-β- santalene, α-humulene, bicyclogermacrene, cadinene, (E,E)-α-farnesene, α-cadinene, (E)-nerolidol , spathulenol, caryophyllene oxide, epi-α-muurolol, cubenol, α- muurolol, α-cadinol Eupatorium polyanthum Part not specified: emmenagogue No biological test No data Sch. Bip. ex Baker Shoots, infusion: for delayed Lorentz 1770 (CORD) menstruation COS, ERI, MIS Eupatorium squarrulosum Part not specified: digestive, No biological test No data Hook. & Arn. diaphoretic Rodríguez 246a (SI) BAI, ERI, MIS, SFE Eupatorium subhastatum Aerial parts: contraceptive, Aerial parts: analgesic activity Aerial parts. 5,7,3',4-tetrahydroxy-6- Hook. & Arn. emmenagogue, vulnerary, to methoxyflavanone 125 Pilarcito relieve pruritis Ariza Espinar 2047 (CORD) BAI, COR, COS, ERI, MIS, SFE

126 Eupatorium tanacetifolium Part not specified: digestive, No biological test No data Gillies ex Hook. & Arn. diaphoretic Tomo34(1-2):7-365.2009 Fabris 4754 (LP) BAI, COR, COS, ERI, MIS, SGO Flaveria bidentis (L.) Aerial parts: stimulant, digestive, Dried aerial parts: insecticide, Root + aerial parts. α-terthienyl and 5- Kuntze emmenagogue, antiseptic, for antiparasitic, antiviral, and (3-buten-1-ynyl)- 2,2′-bithienyl Fique, contrayerba, balda, treating wounds externally, antibacterial activity; β- Leaf. Quercetin, 3, 7, 3’, 4’- dandá, valda, chasca, chasca abluent, vermifuge, alexipharmic, glucuronidase and aldose- tetrasulphate, quercetin-3-acetyl-7, 3’, yuyo, dauda, flor amarilla, febrifuge; decoction: for cough reductase inhibition; 4’-trisulphate, quercetin 3, 7, 3’- ñancuñán, sunchillo, solo, BAI, CAT, CHA, COR, COS, ERI, anticoagulant effect trisulphate: sulphated flavonoids quejatulpino flor amarillo FOR, JUJ, LPA, LRI, MEN, MIS, Dried flowers. Astragalin, kaempferol, Ariza Espinar 2813 (CORD) NEU, RNE, SAL, SDE, SFE, SJU, quercetin-3-acetyl-7, 3’, 4’-trisulphate: SLU, TUC flavonoids Flaveria haumanii Dimitri Leaf + flowers: stimulant Aerial parts: antioxidant Leaf. Quercetin 3, 7, 4’-trisulphate, & Orfila digestive, emmenagogue, activity quercetin 3, 4’-disulphate, quercetin 3- Flaveria bidentis var. antiseptic, for treating wounds sulphate, isorhamnetin 3, 7 disulphate, angustifolia Kuntze externally, abluent, vermifuge, isorhamnetin 3-sulphate Ariza Espinar 2768 (CORD) alexipharmic, febrifuge Root. α-terthienyl BAI, CAT, COR, ERI, JUJ, LPA, Flowers. Isorhamnetin 3, 7 disulphate, LRI, MEN, RNE, SAL, SDE, SFE, isorhamnetin 3-sulphate SJU, SLU (sub nom. F. bidentis var. angustifolia) Flourensia oolepis S. F. Blake Leaf + flowers: digestive, Aerial parts essentials oil: Leaf + stem. 2'-4'-dihydroxy chalcone: Chilca expectorant repellent and toxic effect flavonoid; euparin: oxygen heterocycle; Ariza Espinar 2801 (CORD) CAT, COR, SLU ilicic acid: sesquiterpene Aerial parts essentials oil. τ- muurolene, santolinetriene, 2- methylene-4,8,8-trimethyl-4-vinyl- bicyclo[5.2.0]nonane, δ-cadinene, γ- gurjunene Gaillardia cabrerae Covas Aerial parts, infusion: analgesic, Aerial parts: antiparasitic Aerial parts: Helenalin KURTZIANA Margarita pampeana, marga- antiseptic, for skin affections activity (antiplasmodial, anti- rita de la sierra, botón de oro (alopecia and scurf) trypanosomal) Cabrera 19438 (LP) LPA

Gaillardia megapotamica Leaf + flowers: anti-neuralgic, Inflorescence: gastroprotective Dried aerial parts. Helenalin, 11-13- BARBOZA, G.E.etal.MedicinalfloraofArgentina (Spreng.) Baker var. against the alopecia and the scurf, effect dihydro 11-β-13-epoxy aromatin; megapotamica to relieve the seborrhoea, Aerial parts: antioxidant nepetin; linifolin B: sesquiterpenes Topasaire, botón de oro, topa- hypotensive activity sadre, topa-sangre, bullén BAI, CAT, COR, COS, ERI, LPA, Hunziker & Di Fu lvio 21375 MEN, NEU, RNE, SFE, SLU (CORD) Gaillardia megapotamica Leaf + flowers: anti-neuralgic, No biological test Dried aerial parts. Helenalin, nepetin, var. radiata (Griseb.) Baker against the alopecia and the scurf, mexicanin I: sesquiterpenes; nepetin: Topasaire to relieve the seborrhoea flavone; 2β-hydroxy-2,3- Ariza Espinar 2820 (CORD) BAI, CAT, CHA, COR, ERI, LPA, dihydrohelenalin: pseudoguaianolide LRI, SAL, SDE, SFE, SJU, SLU, TUC Gaillardia megapotamica Aerial parts: analgesic, antiseptic, Aerial parts: antiulcerogenic Aerial parts. Mexicanin, helenalin: var. scabiosoides (Arn. ex anti-neuralgic, against the alopecia activity; antiparasitic activity pseudoguaianolides, acetylenic DC.) Baker and the scurf, to relieve the (antiplasmodial, anti- sulfoxide; desacetyl linifolin B, linifolin Topasaire, choique-la wen, seborrhoea trypanosomal and anti- B, 11β-Hydroxy-13-chloro-11,13, - botón de oro, manzanilla BAI, CAT, COR, COS, ERI, LPA, leishmanial) dihydroaromatin, 11 β, 13-Epoxy-11, Hunziker 9900 (CORD) LRI, MEN, NEU, RNE, SAL, 13-dihydroaromatin, 8,10-bis-epi- SDE, SFE, SJU, SLU, TUC mikanokryptin: guaianolides Galinsoga parviflora Cav. Aerial parts: antiscorbutic, Entire plant: hypotensive and Aerial parts. Caffeic acid: Albahaca silvestre vulnerary hypothermic activity phenylpropanoid; cosmosiin: flavone Subils 2252 (CORD) Dried aerial parts, infusion: Dried flowers: allergenic febrifuge; decoction: against activity hepatic diseases BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC Gamochaeta americana Aerial parts: abluent Dried aerial parts: No data (Mill.) Wedd. Dried entire plant, decoction: to antibacterial activity Plateadita, platita treat urinary tract infections; Ariza Espinar 1679 p.p. infusion: antitussive, against pox, (CORD) measles and varicella; for pimples Root, infusion: for lumbago BAI, COR, COS, ERI, JUJ, LPA, LRI, NEU, RNE, SCR, SFE, SLU, 127 TDF

128 Gamochaeta calviceps Aerial parts: abluent No biological test No data (Fernald) Cabrera BAI, CAT, CHA, COR, COS, ERI, Tomo34(1-2):7-365.2009 Ariza Espinar 2993 (CORD) FOR, JUJ, LPA, LRI, MIS, SFE, SJU, SLU Gamochaeta coarctata Aerial plant: digestive, bequic, No biological test No data (Willd.) Kerguélen pectoral, vulnerary Diuca, leguén, quito-quito, Leaf: cicatrizant uira-uira, vira-vira, peludillo BAI, CAT, CHA, CHU, COR, Ariza Espinar 1702 (CORD) COS, DFE, ERI, JUJ, LPA, LRI, MEN, MIS, NEU, SAL, SJU, TUC Gamochaeta falcata (Lam.) Aerial parts: antiviral, against the No biological test No data Cabrera herpes, abluent, for treating Ariza Espinar 3074 (CORD) wounds externally BAI, CAT, COR, COS, ERI, LPA, SAL, SFE Gamochaeta filaginea (DC.) Aerial plant: digestive No biological test No data Cabrera BAI, CAT, COR, COS, ERI, LPA, Kurtz 309a (CORD) LRI, MEN, MIS, RNE, SFE, SJU, SLU Gamochaeta pensylvanica Aerial parts: antiviral, against the No biological test No data (Willd.) Cabrera herpes, abluent, for treating Borrajilla wounds externally Ariza Espinar 1671 (CORD) Dried entire plant, infusion: antitussive BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, MIS, SFE, SJU, TUC Gamochaeta platensis Part not specified: vulnerary, anti- No biological test No data (Cabrera) Cabrera inflammatory (pleuritis) Cabrera 6582 (LP) BAI, CORD, CHA, ERI, FOR KURTZIANA Gamochaeta simplicicaulis Aerial parts: antiviral, against the Dried aerial parts: antioxidant Aerial parts. Isorhamnetin, quercetin, (Willd. ex Spreng.) Cabrera herpes, abluent, for treating activity; lipid peroxide formation isorhamnetin-3-glucoside, caffeic acid, Ariza Espinar 3072 (CORD) wounds externally inhibition; DNA polymerase chlorogenic acid, isochlorogenic acid, BAI, COR, DFE, JUJ, SAL inhibition ferulic acid: polyphenolic compounds.

Gnaphalium andicola Phil. Medicinal No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Vira-vira CHU, MEN, NEU, RNE Chiapella 1851 (CORD) Gnaphalium Flowers + leaf: digestive, hepatic, Dried aerial parts: tyrosinase Dried aerial parts. Flavone,5-7- cheiranthifolium Lam. antispamodic, antitussive, inhibition dihydroxy-3-8-dimethoxy: flavonol; Marcela macho, vira-vira, febrifuge luteolin-4'-0-β-D-glucoside: flavone marcela, marcelita Flower + leaf + stem, infusion: Di Fulvio 572 (CORD) emmenagogue, abortive BAI, COR, ERI, JUJ, LPA, LRI, MEN, SFE, SLU Gnaphalium gaudichau- Flowers + leaf: digestive, against Dried entire plant: Dried aerial parts. 5-8-dihydroxy-3-6- dianum DC. the influenza, anti-inflammatory anticrustacean activity 7-trimethoxy flavone: flavonol; 5-8- Marcelita, vira-vira, caa- Dried aerial parts, infusion: Leaves, young stem + seeds: dihydroxy-6-7-dimethoxy flavone: guazú emmenagogue, carminative, anti- antifungal activity flavone; ent pimara-8(14)-15-dien-19- Hunziker 9057 (CORD) emetic oic acid, ent pimara-8(14)-15-dien-3-α- BAI, CAT, CHA, COR, COS, ERI, ol: diterpenes FOR, JUJ, LRI, MEN, MIS, NEU, RNE, SAL, SFE, SJU, SLU, TUC Gnaphalium moelleri Phil. Medicinal No biological test No data Santa María CHU, NEU, RNE Cabrera 4986 (LP) Gnaphalium tarapacanum Dried aerial parts, infusion: No biological test No data Phil. antitussive Vira-vira, huira-huira, uira- Part not specified: respiratory uira disorders Anderson 2391 (CORD) CAT, COR, JUJ, LRI, SAL, SLU, TUC Gochnatia argentina Medicinal No biological test Dried aerial parts. Capensin, fraxetin, (Cabrera) Cabrera CAT, CHA, COR, COS, ERI, fraxidin: coumarin; hispidulin: flavone Salvia blanca, guira-guira, FOR, SDE, SFE, TUC vira-vira Hunziker 17573 (CORD) Gochnatia glutinosa (D. Medicinal Aerial parts: antibacterial and Dried aerial parts. 8-hydroxy-3-7-11- Don) Hook. & Arn. CAT, JUJ, LPA, LRI, MEN, NEU, antifungal activities trimethy dodeca-cis-2-trans-6-10-trien- Jarillilla, sacanza, acancio, SAL, SJU, SLU, TUC 13,1-olide: sesquiterpene; 3'-4'-5'-

jarililla trihydroxy-3-7-dimethoxy flavone: 129 Hunziker 13933 (CORD) flavonol; ent pimara-8(14)-15-diene-3-β- 18-diol: diterpene

Gochnatia palosanto Cabrera Bark: for hernia and prolapse No biological test Dried aerial parts. 2-methylbutyrate 130 Palo santo JUJ, SAL, TUC elephantopin, deacyl-deoxy, germacra- Tomo34(1-2):7-365.2009 Hunziker 11394 (CORD) 1(10)-4-11(13)-trien-2-14-6-12- diolide,8-(3-methyl-butanoyl-oxy): (2R-6R-7R-8S): sesquiterpenes Gochnatia polymorpha Dried aerial parts, infusion: in Dried aerial parts: Dried aerial parts. Oleanolic acid, subsp. ceanothifolia (Less.) lung affections, for respiratory antitrypanosomal and bactericide ursolic acids, α-amyrin Cabrera illnesses; decoction: anti- activity Dried leaf. Proline, 4-hydroxy-n- Cambará inflammatory Dried leaf: methyl proline: aminoacid Tressens 5785 (CTES) Leaf and flowers: against catarrh, anti-inflammatory and Dried root. 1-2-dehydro-1-14-dihydro pectoral antiedematogenic activity bisabolene: 15-oxo costunolide: COS, MIS sesquiterpenes Grindelia chiloensis Leaf: antirheumatic, antinephritic, Aerial parts: Proteolytic, Dried aerial parts. Caryophyllene, (Cornel.) Cabrera analgesic molluscicidal, and antibacterial germacrene D: sesquiterpenes; grindela- Botón de oro, melosa, melosilla, CHU, LPA, MEN, NEU, RNE, activity 6-8(17)-dienoic acid, grindelic acid, mata amarilla, virreina SCR Resin: antimicrobial activity oxo grindelic acid,: diterpenes; Bernardello 239 (CORD) quercetin, kaempferol 3-methy ether, kaempferol 3,4’-dimethy ether: flavonoids Grindelia pulchella var. Aerial parts: alexipharmic, Aerial parts: antioxidant Aerial parts essential oil. discoidea (Hook. & Arn.) A. febrifuge, antirheumatic activity Aromadendrene, α-bisabolene, γ- Bartoli & Tortosa (sub nom. G. discoidea) cadinene: sesquiterpenes; bornyl Quilcha amarilla, botoncillo, BAI, CHU, COR, DFE, ERI, LRI, acetate, camphene, carvone: pichana amarilla MEN, SDE, SLU, TUC monoterpenes; cordobic acid: diterpene; Grindelia discoidea Hook. & : flavonol (sub nom. G. Arn. discoidea) Ariza Espinar 1607(CORD) Grindelia pulchella Dunal Aerial parts: alexipharmic, No biological test Dried aerial parts. Kaempferol, var. pulchella febrifuge, antirheumatic quercetin, quercetin-3-methyl ether,

Quilcha amarilla, botoncillo, BAI, CAT, CHA, CHU, COR, COS, quercetin-3,3’-dimethyl ether, KURTZIANA pichana amarilla DFE, ERI, JUJ, LRI, MEN, RNE, quercetin-3,3’,7-trimethyl ether, Ariza Espinar 1304 (CORD) SAL, SDE, SFE, SJU, SLU, TUC kaempferol, 3-methy ether, kaempferol, 3,4’-dimethy ether: flavonoids; grindelic acid, 18-hydroxy grindelic acid: diterpenes

BARBOZA, G.E.etal.MedicinalfloraofArgentina Grindelia scorzonerifolia Part not specified: expectorant Aerial parts: antibacterial Plant. 4-β-hydroxy-19-normanoyl Hook. & Arn. and hypotensive effects activity oxide, 4-α-hydroxy-18-normanoyl Hunziker 7262 (CORD) BAI, CHA, COR, COS, DFE, ERI, oxide: norditerpenoids; 18-O-α-l- LPA, MIS, SFE arabinopyranosylmanoyl oxide, jhanol, 18-hydroxy-13-epi-manoyl oxide (5): diterpenoids Dried aerial parts. Caryophyllene oxide, spathulenol: sesquiterpenes; jhanol: diterpene Gutierrezia gilliesii Griseb. Aerial parts: against the influeza, No biological test Dried aerial parts. Bisabolen-1-one: Canchalagua antirheumatic, febrifuge, sesquiterpene; labdane 2: diterpene Ariza Espinar 2937 (CORD) stomachic BAI, CAT, CHU, COR, LPA, LRI, MEN, NEU, RNE, SJU, SLU, TUC Gutierrezia mandonii (Sch. Part not specified: for the liver No biological test Aerial parts. Gutierrezianolic acid [2- Bip.) Solbrig and vesicle pains methylbutyrate], methyl isobutyrate Amaicha chica, canchalagua, CAT, JUJ, LRI, SAL, TUC canchalahua, chillauva Barboza 701 (CORD) Haplopappus baylahuen J. Aerial parts: digestive, Dried entire plant: kidney stone Dried leaf + stem. Kaempferol, Rémy aphrodisiac, emmenagogue, dissolution effect, alanine rhamnetin, rhamnocitrin, quercetin, Baila bien antitussive, antidiarrheal, aminotransferase inhibition quercetin 3-O-methyl ether: flavonoids; Kiesling 7508 (SI) antidysenteric, antiseptic, Dried leaf + stem: persicogenin, sakuranetin, velutin: choleretic, cholagogue properties antihepatotoxic activity flavones; coumarins SJU Leaf: antioxidant activity Part not specified: uterine relaxation effect Haplopappus glutinosus Medicinal No biological test Dried aerial parts. 4-hydroxy Cass. CHU, NEU, RNE, SCR Acetophenone: benzenoid Baylahuen, buchú, huenutrol Dried leaf + stem. 4-hydroxy Benzoic Barboza 1209 (CORD) acid: benzenoid caffeic acid: phenylpropanoid; β-farnesene: sesquiterpene; 3'-4'-7-trihydroxy-5-0- galactosy flavone: flavone 131

132 Haplopappus rigidus Phil. Aerial parts: digestive, Dried aerial parts: Dried entire plant. Betuletol: flavonol; Baila buena, baila bien, vai- aphrodisiac, emmenagogue, anticrustacean, antibacterial, and rigiduside, rigidusol, deacetyl igidusol: Tomo34(1-2):7-365.2009 lahuén, baylahuén antitussive, antidiarrheal, cytotoxic activity; diterpenes Charpin 20795 (SI) antidysenteric; infusion: to treat leishmanicidal effect Aerial parts. Rigiduside (13-O-β- chills, for stomach pains xylopiranosylmanool): glyco- Dried branches, decoction: to diterpenoid, rigidusol [13-hydroxy-18- treat urinary tract infections, and acetoxy-cis-cleroda-3,14-diene (8βH, against diarrhea 10βH, 19β, 20α form)], CAT, SAL deacetylrigidusol [13,18-dihydroxy-cis- cleroda-3,14-diene (8βH, 10βH, 19β, 20α form)]: diterpenoids; 3,5,7- trihydroxy -6,4’ -dimetoxyflavone: flavonoids; 18 acetoxy cis clerode 3,13 Z dien 15 oic acid, 5, 4' dihydroxy 7 methoxyflavonone, 3,5,7 trihydroxy 6,4' dimethoxyflavone Helenium argentinum Ariza Part not specified: digestive No biological test No data Botón de oro COR, SDE, SLU Ariza Espinar 2235 (CORD) Helenium donianum (Hook. Aerial parts: against the influenza, Dried entire plant: antibacterial Dried aerial parts. 2-deoxy & Arn.) Seckt antirheumatic, febrifuge, stomachic activity florilenalin,: 4-O-β-D-glucopyranoside, Yerba del ciervo, topasaire CAT, COR, LRI, MEN, SAL, linifolin A, alternilin, linifolin A, 6(S)- Ariza Espinar 3082 (CORD) SDE, SJU, SLU, TUC angeloyl-oxy: (1S,5R,7R,8S,10R) guaia-2-11(13)-dien-8-12-olide: sesquiterpenes Heterosperma ovatifolium Aerial parts: vulnerary, abluent No biological test No data Cav. CAT, COR, JUJ, LPA, LRI, SAL, Ariza Espinar 2815 (CORD) SDE, SJU, SLU, TUC KURTZIANA Heterosperma tenuisectum Aerial parts: digestive, stomachic No biological test No data (Griseb.) Cabrera CAT, COR, JUJ, LRI, SAL, SJU, Roquecito SLU, TUC Hunziker 9165 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Heterothalamus alienus Aerial parts: febrifuge, tonic Aerial parts + root: antifungal Aerial parts. Rutin, spathulenol, (1R,7S)- (Spreng.) Kuntze stomachic, antinephritic activity germacra-4(15),5,10(14)-trien-1β-ol, Romerillo, romerillo dulce, Branches: to treat amnesia, Aerial parts: antioxidant padmatin 3-acetate, sakuranetin, (2R,3R)- pichana asthenia; brain tonic and stimulant activity 3-acetoxy-5,7,4’-trihydroxyflavanone, Bernardello 396 (CORD) Dried leaf, decoction: antipyretic Aerial parts essential oil: (2R,3R)-dihydroquercetin-7,3’,4’-trimethyl COR, LRI, SLU virucidal activity ether; (2R,3R)-dihydroquercetin-7,4’- dimethyl ether, (2R,3R)-3-acetoxy-5,7,4′- trihydroxyflavanone; docosanoic cinnamate, 7-hydroperoxy-5,6-E-dehydro- 6,7-dihydronerol and 2-(3-methylbut-3- enyl)-3-methyl-2,5-dihydrofuran Dried leaf. Bisabolene-1-4- endoperoxide, α eudesmol: sesquiterpene; dolosanoic-cinnamate: phenylpropanoid; neryl acetate: monoterpenes; ent labdan-15-oic acid 8-β-hydroxy 8-O-d-xylopyranosyl: diterpene Hieracium tandilense Part not specified: astringent No biological test No data Sleumer BAI Hunziker 11552 (CORD, SI) Hymenoxys anthemoides Aerial parts: alexipharmic, No biological test Part not specified. Anthemoidin, (Juss.) Cass. antitussive; infusion: for themoidin: sesquiterpenoids Botón de oro, cassini, cephalalgia, and to induce sneezing topasaire BAI, CAT, CHA, COR, COS, Di Fulvio 349 (CORD) DFE, ERI, FOR, LPA, MEN, SAL, SDE, SFE, SJU, SLU, TUC Hypochaeris chillensis Flowers: purgative, No biological test No data (Kunth) Hieron. emmenagogue, aperitive Ariza Espinar 2758 (CORD) BAI, CAT, CHA, COR, COS, ERI, JUJ, LPA, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC Hypochaeris elata (Wedd.) Medicinal No biological test No data Griseb. CAT, COR, JUJ, LRI, SAL, SJU, Achicoria SLU, TUC 133 Ariza Espinar 3068 (CORD)

Hypochaeris microcephala Aerial parts: contraceptive No biological test No data 134

(Sch. Bip.) Cabrera Flowers: purgative, Tomo34(1-2):7-365.2009 Bonzani 9 (CORD) emmenagogue, aperitive BAI, CAT, COR, COS, DFE, ERI, FOR, LPA, MIS, SFE Hypochaeris pampasica Root: tonic stimulant No biological test No data Cabrera BAI, CAT, CHU, COR, COS, Ariza Espinar 1793 (CORD) DFE, ERI, LPA, LRI, MEN, RNE, SAL, SJU, SLU Hysterionica jasionoides Aerial parts: antiseptic, abluent, No biological test No data Willd. for treating wounds externally Ariza Espinar 2755 (CORD) BAI, CAT, CHA, COR, FOR, JUJ, LPA, LRI, MEN, NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC Jungia floribunda Less. Aerial parts: for warts Aerial parts: larvicidal activity No data Higo del bosque, yaguaretí- COS, MIS pí, yaguaretí-pó Pedersen 1669 (LP) Jungia polita Griseb. Aerial parts: diuretic, anti-sclerotic, Dried aerial parts: Dried aerial parts. β-amyrin, lupeol: Zarzaparrilla, viña hypotensive, for skin affections; anti- antitrypanosomal activity triterpene; 8-α-hydroxy cyperotundone, Hunziker 12375 (CORD) hyperlipidemic and bradicardic 6-β-hydroxy guaia-4-11-dien-3-one: Leaf: for humoral and blood sesquiterpenes; pectolinarigenin: diseases flavone; salvigenin, pectotinarngenin, CAT, COR, JUJ, LRI, SAL, SLU, TUC pinoresinol Laennecia sophiifolia Part not specified: alexipharmic, Dried aerial parts: anti- Dried aerial parts. Apigenin: flavone; (Kunth) G.L.Nesom antirheumatic, diuretic inflammatory activity hawtriwaic acid: diterpene; β- Hierba de la víbora, yerba de CAT, CHA, COR, JUJ, LPA, LRI, sitosterol: sterol la araña, yerba del zorro MEN, SAL, SDE, SJU, SLU, TUC Hunziker 9777 (CORD)

Madia sativa Molina Seed: hydrogogue, cathartic, Dried entire plant: reverse Dried root. 2-(h): 6-(2-hydroxy- KURTZIANA Yuyo aceite, mady, gomosa digestive transcriptase inhibition acetyl)-2-2-domethyl-7-hydroxy Barboza 1242 (CORD) CHU, MEN, NEU, RNE, TDF benzopyran,: oxygen heterocycle; 6- acetyl-2-2-dimethyl chroman-4-one,: chromone; 13-(r)-14-(r)-15-trihydroxy labd-7-ene: diterpene; 6-acetyl-2-iso- pentenyl-1-hydroxy benzene: benzenoid

Microliabum candidum Medicinal Aerial parts: antioxidant Dried flower + leaf. Patuletin, BARBOZA, G.E.etal.MedicinalfloraofArgentina (Griseb.) H. Rob. (sub nom. L. candidum) activity quercetin, scoparol: flavonol; tatridin A: candidum Griseb. CAT, COR, LRI, SLU, TUC sesquiterpene var. candidum (sub nom. L. candidum) Ariza Espinar 2149 (CORD) Mikania cordifolia (L. f.) Aerial parts: emmenagogue, Stem: antitrypanocidal and Aerial parts. β-Farnesene, mikania Willd. alexipharmic, antirheumatic, and moulting inhibition melampolide 3-A: sesquiterpenes; Guaco, guáko, matacampo, for respiratory and intestinal Leaf: antitrypanosomal activity campesterol, stigmasterol, β-sitosterol, β- pompero kocho, nakoló letaá, disorders amyrin, lupenone, lupeol, friedelin, palotr’óik Root: purgant pseudotaraxasterol, taraxasterol, Hunziker 19454 (CORD) BAI, CAT, CHA, COR, COS, ERI, taraxasteryl acetate, β-amyrin acetate, FOR, JUJ, MIS, SAL, SDE, SFE, TUC epitaraxerol, β-amyrin acetate, lupeoyl acetate: triterpenoids Dried leaf. 3-5-di-o Caffeoylquinic acid: phenylpropanoid Flowers essential oils. Myrcene, spathulenol, caryophyllene oxide, germacrene D, α-selinene, limonene, α- muurolol, α-humulene, γ-cadinene Mikania glomerata Spreng. Plant: expectorant, Plant: antimicrobial, anti- Aerial parts. 2-H-1-benzopyran-2-one, Guaco Leaf: for asthma and bronchitis, to alergic, antivenin, and anti- o-coumaric acid: coumarins; 15β- Vervoorst & Cuezzo 7590 C treat cold, flu, fever, and inflammatory activity hydroxy-ent-kaur-16-en-19-oic acid, (LP) rheumatism Leaf: antispasmodic and 17-hydroxy-ent-isok:en -19-oic acid; MI broncodilatador activity; effects kauran-type diterpenes; kauranes; on allergic pneumonitis; derivatives; triterpenes antidiarrhoeal effect Leaf explants. Campesterol, Roots, stems + leaf: stigmasterol and β-sitosterol: steroids; antiophidian activity coumarin Mikania hirsutissima DC. Plant: expectorant, antirheumatic, Aerial part: antimicrobial Aerial parts. 2β,16α,17-trihydroxy-ent- Ferrucci et al. 576 (CTES) antinephritic, and against diarrhea activity; proliferative activity kauran-19-oic acid, 3β,16α,17- and neuralgia toward peripheral blood trihydroxy-ent-kauran-19-oic acid, COS, MIS mononuclear cells; strong 11α,15β-dihydroxy-7-O-β-d- cytotoxic activity glucopyranosyl-ent-kaur-16-en-19-oic acid, 1α,15β-dihydroxy-7-O-β-d- glucopyranosyl-ent-kaur-16-en-19-oic acid: ent-kaurenoic acid derivatives;

1,5-dicaffeoyl-quinic acid, 2-O- 135 glucosyloxy-4-methoxy-cinnamic acid, phenethyl alcohol glucoside, phenethyl-

Mikania hirsutissima DC. 1-O-β-d-apiofuranosyl (1→2) β-d- 136

(continuation) glucopyranoside (sayaendoside), 3,6- Tomo34(1-2):7-365.2009 dihydroxy-β-ion-9-ol; mikanialactone: bisnorkaurenic acid-type diterpenelactone; mikaniahumulene I and II: norhumulene-type sesquiterpenes; coumarin; flavone Mikania mendocina Phil. Part not specified: alexipharmic, No biological test Dried flower + leaf. 8-epi Inunolide; Del Vitto 4900 (CORD) antirheumatic, antispamodic, 15-acetoxy-1-β-10-α-epoxy, venereal disease quadrangolide,14-O-acetyl: MEN, NEU, RNE sesquiterpenes Aerial parts. Quadrangolide, 15- norguaianolides, guaianolides, germacranolides Mikania micrantha Kunth Dried aerial parts, infusion: as an Aerial part: antibacterial and Dried aerial parts. α-amyrin: triterpene; Guaco, charrúa, bejuco, isipó antidote, vulnerary, for diabetes trypanosomal activity coumarin; alpinetin: flavanone; Cerana 1390 (CORD) Leaf, decoction: antivenin, mikamicranolide: sesquiterpene; mikanin- against malaria, to treat urinary 3-O-sulfate: flavonol; mikanolide tract infections; infusion: febrifuge (1,10:2,3-diepoxy-6,8-dihydroxy-11- Stem: alexipharmic, cicatrizant, vinylgermacr-4-ene 12,14-di-γ-lactone and febrifuge, for conjunctivitis 7,10a-dimethyl-1a,1b,2a,6a,7,9a,10,10a- BAI, CHA, COS, DFE, ERI, FOR, octahydro-4H-6,3-methenofuro[3,2- JUJ, MIS, SAL, SFE, TUC c]bisoxireno[f,h]oxacycloundecin-4,8(6H)- dione); mikanin, , eupafolin, 3,4′,5,7-tetrahydroxy-6-methoxyflavone 3- O-β-glucopyranoside, luteolin, 3,5-di-O- caffeoylquinic acid n-butyl ester, 3,4-di-O- caffeoylquinic acid n-butyl ester Whole plant essential oil. α-thujene, β- terpinene, α-pinene, β-myrcene, β-pinene, t-butylbenzene, α-terpinene, β-ocimene, KURTZIANA linanyl oxide, linalool, carveol, menthol, p- cymene-2-ol, terpinene-4-ol, myrthenal, verbenone, geraniol, geranial, thymol, eugenol, geranyl-acetate, α-cubebene, γ- elemene, α-copaene, β-caryophyllene, D- germacrene, δ-cadinene

Mikania periplocifolia Aerial parts: alexipharmic, Dried leaf: cytotoxic activity Dried aerial parts. BARBOZA, G.E.etal.MedicinalfloraofArgentina Hook. & Arn. antirheumatic, sedative Aerial parts: antifungal activity; Germacrene D, γ-cadinene, Guaco, guacho chico, mikania Dried leaf: against rheumatism, anti-gout globulol: sesquiterpenes; guaco, enredadera del campo, and for intestinal disorders monoacetoxy triol: diterpene; guaco del río, loconte, na koló, BAI, CAT, CHA, COR, COS, ERI, mikanolide, miscandenin; tapa cerco FOR, JUJ, LRI, MEN, MIS, SAL, 3β-hydroxy-11βH,13- Subils 2231 (CORD) SFE, SJU, SLU, TUC dihydroisabelin, 11βH,13- dihydrodeoxymikanolide and mikaperiplocolide: dilactones; geranylneryl derivatives Mutisia acuminata var. Leaves: vulnerary, antiulcer, No biological test No data paucijuga (Griseb.) Cabrera purgative, diuretic, antibiotic, Chincercoma, chinchircoma, cholagogue, cardioactive, chinchiricoma, chinchiricoma emollient amarilla, chinchirconca, JUJ, SAL, TUC puscayo Cabrera 13894 (LP) Mutisia decurrens Cav. Root: against the alopecia No biological test Dried aerial parts. Lupeol, lupeol Mutisia CHU, NEU, RNE acetate: triterpenes Bernardello 596 (CORD) Mutisia friesiana Cabrera Leaf: antitussive, expectorant, Aerial parts: bactericidal, Aerial parts. Mutisicoumaranones A, B, Chinchircoma colorada, antispasmodic antifungal and radical C, D: methylcoumaranones; caffeic acid romero, chincharcuma, JUJ, SAL scavenging activity derivatives; quercetin; 1-(2-Hydroxy-6- romerillo methylphenyl)-5,9-dimethyl-4,8-decadien- Morrone 2618 (SI) 1-one, 5,9,13-Trimethyl-10-hydroxy-1-(2- hydroxy-6-methylphenyl)-4,8,12- tetradecatrien-1-one, 5,9,13-Trimethyl-11- hydroxy-1-(2-hydroxy-6-methylphenyl)- 4,8,12-tetradecatrien-1,10-dione, 5,9,13- Trimethyl-13-hydroxy-1-(2-hydroxy-6- methylphenyl)-4,8-tetradecadien-1,10- dione, 5,9,13-Trimethyl-13-hydroperoxy- 1-(2-hydroxy-6-methylphenyl)-4,8- tetradecadien-1,10-dione, 2,10-Dimethyl- 2-(4-methyl-3-pentenyl)-2H,5Hpyran [3,2- c] [1] benzopyran-5-one, 2,10-Dimethyl-2- (5-hydroxy-4,8-dimethyl-3,7-nonadienyl)- 2H,5H-pyran [3,2-c] [1]benzopyran-5-one,

3,4-Dihydro-3-hydroxy-2,6-dimethyl-2-(5- 137 methyl-4-hexenyl)-2H,5H-pyran [2,3-b] [1] benzopyran-5-one

Mutisia hamata Reiche Aerial parts: hemostatic, No biological test No data 138

Chinchircuma, chinchircoma antitussive, expectorant, Tomo34(1-2):7-365.2009 blanca, chinchircuma blanca, antispasmodic, digestive, help with flor de tormenta childbirth Cabrera 8756 (LP) JUJ, SAL Mutisia retrorsa Cav. Medicinal No biological test Dried aerial parts. Lupeoyl acetate: Granadilla, virreina CHU, MEN, NEU, SCR triterpene; germacrene D: sesquiterpene Cocucci 2479 (CORD) Mutisia saltensis Cabrera Leaf: antitussive No biological test No data Chinchircoma JUJ, SAL Carmelich 190 (LP) Mutisia sinuata Cav. Part not specified: digestive No biological test No data Granadilla MEN, SJU Cocucci 567 (CORD) Mutisia spinosa Ruiz & Pav. Root: against the alopecia No biological test Aerial part. 3,7-dimethyl-3-acetoxy-6- Granadilla CHU, NEU, RNE, SCR hydroxy-octa-1,7-diene Cocucci 2421 (CORD) Roots. Piloselloidan

Mutisia subspinosa Cav. Part not specified: diuretic, Dried entire plant: No data Granadilla astringent, depurative antibacterial activity Barboza 580 (CORD) LRI, MEN, SJU Nardophyllum armatum Dried aerial parts, infusion: for Aerial parts: antioxidant and Aerial parts. Flavonoids, phenolic (Wedd.) Reiche epidermal ailments, digestive, antibacterial activity compounds Suruyanta, suri llanta, suri, antitussive, febrifuge, stomachic surianta, suriante, surincho, Leaf : antirheumatic suriyampa, suriyante CAT, JUJ, LRI, SAL, SJU, TUC Kurtz 11296 (CORD) Nassauvia axillaris (Lag. ex Part not specified: antitussive, No biological test Aerial parts. 29-nor-20-oxolupeol, 3β- Lindl.) D. Don febrifuge, digestive Hydroxylupan-29-oic acid, 3β-

Uña de gato, chuchicaña, CAT, CHU, JUJ, LRI, MEN, Hydroxy-20α,21α-epoxyursane, E- KURTZIANA choque chuquicauguia, chur- NEU, RNE, SAL, SJU, SLU, TUC Ferulic acid eicosyl ester, E-Ferulic cocauguia, chuquicaña, cho- acid eicosyl ester, E-Ferulic acid checanga, calla, matanegra, docosyl ester canguilla, choque canlla, choque caya, cola de león Hunziker 19805 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Nassauvia revoluta D. Don Part not specified: stomachic, No biological test Dried aerial parts. Coniferyl-alcohol- Cola de quirquincho, styptic 4-O-farnesyl ether: phenylpropanoid; calahuala CHU, MEN, NEU, RNE, SCR benzoic acid, vanillyl alcohol: Chiapella 1710 (CORD) benzenoid; dithiophene,2-(3-4- dihydroxy-but-1-inyl): sulfur compound; nassauvirevolutin B: coumarin Ophryosporus axilliflorus Leaf: anti-syphilitic, astringent, Dried rhizome + leaf: Dried rhizome + leaf. Benzofuran,2-3- (Griseb.) Hieron. against to treat wounds externally analgesic activity dihydro: 2-˜- (1’-formyl-vinyl)-6- Charrúa CAT, COR, JUJ, LRI, SAL, SLU, acetyl-7-hydroxy: oxygen heterocycle; Ariza Espinar 1614 (CORD) TUC chroman-4-one,2-2-dimethyl-6-acetyl: chromone Ophryosporus charua Dried leaf + flowers: anti- No biological test Aerial parts. 5-acetyl-2-[l'- (Griseb.) Hieron. syphilitic, astringent, against to hydroxyisopropyl]-benzofuran, 5-acetyl-2- Charrua treat wounds externally (2-[1,2-dihydroxyisopropyl)]-benzofuran, Hunziker 24422 (CORD) CAT, COR, JUJ, LRI, SAL, SJU, (2S*,3S*)-5-acetyl-2-(2-[l-acetoxy-2- SLU, TUC propenyl])-3- acetoxybenzofuran, toxol: benzofurans; prenylated chromanone, prenylated p-hydroxyacetophenone; benzofuran "dimers' Leaf + flowers essential oil. α-thujene, α-pinene, sabinene, β-pinene, Δ 3- carene, p-cymene, limonene, lavandulol, lavandulyl acetate, β- elemene, humulene, δ-cadinene, dehydrotremetone Ophryosporus piquerioides Entire plant: expectorant, Entire plant: antileishmanial Aerial parts. 3,4-dihydroxy-2,2- (DC.) Benth. ex Baker migraine activity dimethyl-6-7dimethoxychromona, 1β, China wari chilka JUJ, SAL, TUC 5α-dihydroxy-10(14)eudesmene; Cabrera 22661 (LP) scopoletin: benzofuran; syringaresinol: lignan Orthopappus angustifolius Leaf: against toothache, astringent, No biological test No data (Sw.) Gleason tonic Lengua de vaca CHA, COS, ERI, FOR, JUJ, MIS, 139 Hunziker 5454 (CORD) SAL, SFE, TUC

140 Pachylaena atriplicifolia D. Medicinal No biological test Dried aerial parts. α-myrin, lupeoyl Don ex Hook. & Arn. CAT, LRI, MEN, NEU, SAL, SJU acetate: triterpene; β-sitosterol: steroid; Tomo34(1-2):7-365.2009 Hierba santa, oreja de chancho 4-hydroxy-5-methylcoumarin-4-O-D- Barboza 965 (CORD) glucopyranoside Parastrephia quadran- Entire plant: to speed up Aerial parts essential oil: Dried aerial parts. 5-7-dihydroxy-3- gularis (Meyen) Cabrera parturition insecticide activity 3’-4’-8-tetramethoxy Flavone: flavonol; Tola-tola, pupusa de agua, Dried aerial parts, infusion: for (sub nom. P. lepidophylla) scopoletin: coumarin; para-coumaroyl- qóa, tola común, tola huaca, headache oxy tremetone: oxygen heterocycle tola vaca, vaca tola, chacha, Dried branches + leaf, infusion: (sub nom. P. quadrangularis) coba, tola sebosa for headache Aerial parts. 4-hydroxy Acetophenone: Parastrephia lepidophylla (sub nom. Parastrephia benzenoid; ,(1’-cinnamoyl-oxy- (Wedd.) Cabrera lepidophylla) ethyl)benzene: phenylpropanoid; iso Ariza Espinar 2726 (CORD) CAT, JUJ, LRI, SAL, SJU, TUC fraxidin: coumarin; tremetone: oxygen heterocycle (sub nom. P. lepidophylla) Parthenium hysterophorus Dried aerial parts, infusion: hypo- Aerial parts: dermatitis Dried leaf. 11-13-dihydro ambrosin L. tensive, antimalarial, abortive and for producing effect, insecticide and coronopilin: sesquiterpenes; anisic acid: Altamisa, alta misa d el ca mpo, hepatic disorders, emollient, febri- allergenic activity; benzenoid; casticin, astragalin: yerba de la oveja, falsa altamisa, fuge, for dysentery, to treat diabetes; Dried flowers: hypotensive and flavonols; betulin: triterpene altamisa a marga, altamisa del decoction: antidiarrheal, to treat antifungal activity; bordo, chu purujume, yerba de urinary and respiratory tract infections gastroprotective effect la víbora, altamesa Fresh root, infusion: febrifuge and Di Fulvio 433 (CORD) for epilepsy Dried leaf: vermifuge, febrifuge and to treat anemia Flowers + leaf : bitter tonic, febrifuge, analgesic, antineuralgic for welts herpes BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, NEU, SAL, SDE, SFE, SJU, SLU,

TUC KURTZIANA Pascalia glauca Ortega Entire plant: for the sinusitis Dried entire plant: antibacterial Dried aerial parts. Atractyloside, kaur- Chiquilla, sunchillo, seca tierra BAI, CAT, CHA, CHU, COR, activity 16-en-19-oic acid: diterpenes; Wedelia glauca (Ortega) O. COS, ERI, FOR, JUJ, LPA , LRI, (sub nom. W. glauca) limonene, sabinene, α-pinene; Hoffm. ex Hicken MEN, MIS, NEU, RNE, SAL, stigmasterol: steroid Ariza Espinar 2763 (CORD) SDE, SFE, SJU, SLU, TUC (sub nom. W. glauca)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Pectis odorata Griseb. Aerial parts: antituberculosis, No biological test Dried aerial parts. Perilla aldehyde, Manzanilla del monte, antidysenteric, digestive, citral, limonene: monoterpenes comino del campo, guazú- carminative Dried root. Stigmasterol: steroid caá, tomillo, manzanilla del CAT, CHA, COR, COS, FOR, campo, limonillo, yerba del JUJ, LRI, SAL, SDE, SJU, SLU, venado, chinchilla TUC Caro 3481 (CORD) Pectis sessiliflora (Less.) Medicinal No biological test Plant. 6-hydroxy-kaempferol 7-0- Sch. Bip. CAT, COR, JUJ, LRI, SAL, SDE, xylosylglucoside, quercetagetin 7-0- Hunziker 9166 (CORD) TUC galactoside, patuletin, patuletin 3-0- glucoside, patuletin 3-0- rhamnosylglucoside Perezia ciliaris D. Don ex Rhizome: anti-inflammatory No biological test No data Hook. & Arn. CAT, JUJ, LRI, MEN, SAL, SJU, Raíz de marancel, marancel SLU, TUC Hunziker 20937 (CORD) Perezia multiflora (Bonpl.) Dried entire plant, infusion: Dried entire plant: Dried aerial parts. Pereflorin: Less. subsp. multiflora antimalarial, abortive, for hepatic antitrypanosomal activity coumarin; perezia sesquiterpene 1-A: Escorzonera disorders, febrifuge, emollient Leaf: antileishmanial activity sesquiterpene Cerana 1813 (CORD) Root: diuretic, diaphoretic, abortifacient Leaf, infusion: antipyretic CAT, COR, JUJ, MEN, SAL, SJU, SLU, TUC Perezia purpurata Wedd. Leaf: against altitude sickness; Aerial parts: antiviral, No data Marancel, marancela, merenzel, against inflammation, sprains and carminative, sedative, good escorzonera, maranzel macho waist pain against nervous migraine Rodríguez 1376 (LP) CAT, JUJ, LRI, SAL, SJU, TUC Picrosia longifolia D. Don Aerial parts: diaphoretic, No biological test No data Achicoria silvestre refrigerant, diuretic, laxative Ariza Espinar 2863 (CORD) Dried aerial parts, infusion: diuretic antimalarial, refrigerant, demulcent BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, 141 MEN, MIS, NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC

Plazia daphnoides Weed. Part not specified: antidiarrheal No biological test Aerial parts. Kolavenol, naringerin, Toqui, yara tola, tola de and for vesicle pains sakuranetin, isokuranetin, acacetin, 142 canasta JUJ, MEN, SAL genkwanin, lupeyl acetate, α- and γ- Tomo34(1-2):7-365.2009 Hunziker 6154 (LP) curcumene, (-)-9-acetoxycapric acid, lycoserone and its 1‘-epimer, cyclolycoserone and its dehydroderivative; isobutyl-3,4- dihydroxycinnamate, 2-methyl-2- butenyl-3,4-dihydroxycinnamate Essential oil. Phenols and volatile fatty acids Pluchea microcephala R. K. Aerial parts: antidysenteric, No biological test No data Godfrey stomachic Cuatro cantos CAT, CHA, COR, FOR, JUJ, Ariza Espinar 1912 (CORD) SAL, SDE, TUC Pluchea sagittalis (Lam.) Entire plant, infusion: stomachic Dried aerial parts: Dried aerial parts. Caffeic acid: Cabrera Aerial parts: bitter tonic, hepatic, antibacterial, anti-inflammatory, phenylpropanoid; chrysosplenol D: Lucera, hierba lucera, quitoc, coleretic, antispamodic, digestive, carminative, tonic, antipyretic, flavonol; quitoco, lusera, cuatro cantos carminative, cholagogue; decoction: and antioxidant activity; protein Essential oil. Borneol, borneyl acetate: Pluchea quitoc DC. antipyretic, antidysenteric, antitussive, synthesis inhibition, reactive monoterpenes Bocco 318 (CORD) antiseptic, for stomachache, febrifuge, oxygen species generation Leaf. Alkaloids, flavonoids, tannins, venereal diseases, antidiarrheal, anti- inhibition triterpenes alcoholic Root: against the phlebitis Dried leaf: digestive BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MIS, SAL, SDE, SFE, SLU, TUC Porophyllum lanceolatum Part not specified: venereal No biological test Flowers. Quercetin 7-0-glucoside, DC. disease, antispamodic, diaphoretic quercetin 3’-0-glucoside, quercetin 3-0-

Hierba del ciervo, clavelina Fresh leaf: to cause boils to arabinosylrhamnoside, 5, 7, 7, 3’- KURTZIANA Burkart 23875 (SI) suppurate tetrahydroxy-4’-methoxy 3’0-glucoside: CAT, CHA, COS, ERI, FOR, JUJ, flavonoids MIS, SAL, SDE, SFE, TUC Aerial parts essential oil. Linalool, 1,8-cineole, Δ3 –carene-10-al: monoterpenes Root. Bithienyl,2-2': 5-(4-acetoxy-but- 1-ynyl): sulfur compound

BARBOZA, G.E.etal.MedicinalfloraofArgentina Porophyllum obscurum Aerial parts: antispamodic, No biological test Dried aerial parts. Quercimeritrin, (Spreng.) DC. diaphoretic; infusion: for venereal , 3-0-rhamnoside, 7-0- Yerba del venado, cominillo, disease, antispasmodic arabinoside, isorhamnetin, yerba de la gama, ruda BAI, CAT, CHA, COR, COS, quercetagetin: flavonoids blanca, kilkina, curupaimi, DFE, ERI, JUJ, LRI, MEN, MIS, Leaf essential oil. Hexanal, α- and β- quirquina, yerba del ciervo SAL, SDE, SFE, SJU, SLU, TUC pinene, sabinene, myrcene, Δ3-carene, , Ariza Espinar 1597 (CORD) p-cymene, (E)-β-ocimene, γ-terpinene, terpinolene, octa-2,4-dienal, terpinen-4- ol, decanal, trans-carveol, methyl thymol, deca-2,4-dienal, dodecenal, β- elemene, β-gurjunene, β-humulene, α- himachalene, δ-cadinene, β- caryophyllene, trans-sabinene hydrate, undec-1-ene, spathulenol Porophyllum ruderale Aerial parts: diaphoretic, Aerial parts essential oil: Flower. Quercetin 3’0-arabinoside, (Jacq.) Cass. hemostatic, cicatrizant, ophtalmic insecticide and anti- quercetin 7-0-glucoside, gossypetin 4’- Mboi-morotí CAT, CHA, COR, COS, ERI, inflammatory activity methyl ether 3-0-arabinoside, quercetin Ariza Espinar 2155 (CORD) FOR, JUJ, LRI, MIS, SAL, SDE, Aerial parts: antibacterial 7-0-glucoside, gossypetin 4’-methyl SFE, SJU, TUC activity ether 3-0-glucoside: flavonoids Root. Bithienyl,2-2' 5-(but-3-en-1- ynyl): sulfur compound Plant essential oil. Sabinene, α- terpinene, p-cymene, β-ocimene, cis- thujone, 1,3,8 p-mentatriene, spathulenol Leaf essential oil. 1-8: 2-3-dihydro cineol, limonene: monoterpenes Proustia cuneifolia var. Root + leaf: antirheumatic, Dried leaf: antibacterial activity Dried aerial parts. Cedren-14-β-15- mendocina (Phil.) Ariza hydrogogue (sub nom. P. cuneifolia) olide, 9-β-acetoxy-14-α-hydroxy-3-α- Alpete, charcoma, sacha CAT, COR, LPA, LRI, MEN, SJU, senecioyl-oxy: sesquiterpenes; durazno, palo huso, chilca, SLU sakuranetin: flavanone altepe, fia-mate (sub nom. P. cuneifolia)

Hunziker 8857 (CORD) 143

Pterocaulon alopecuroides Aerial parts: hepatic, cephalalgic, Entire plant: antileishmanial Aerial parts. 5-methoxy-6,7- 144

(Lam.) DC. abluent activity methylenedioxycoumarin, 7-(2′,3′- Tomo34(1-2):7-365.2009 Toro-caa morotí CHA, COR, COS, FOR, JUJ, MIS, epoxy-3′-methylbutyloxy)-6- Hunziker 18240 (CORD) SAL, SFE, SLU, TUC methoxycoumarin, 6,7- methylenedioxycoumarin (ayapin), along with a mixture of 6-hydroxy-7- (3′-methylbutyl-2′-en-oxy)-coumarin (prenyletin) and 6-methoxy-7-(3′- methylbutyl-2′-en-oxy)-coumarin (prenyletin-methyl-ether): coumarins Root. Tridec-1-ene-3,5,7,9,11-pentayne I; 2-(buta-3-en-1-ynyI)-5-(pent-1,3- diynyI)- thiophene IV; 2-(hexa-5-en-1,3-diynyl)-5- (prop-1-ynyI)-thiophene V; 2-(3,4- dihydroxybuta-1-ynyI)-5-(pent-1,3- diynyI)-thiophene VI; 2-(5,6- dihydroxyhexa-1,3-diynyl)-5-(prop-1- ynyl)-thiophene VII; 2-(4-chloro-3- hydroxybuta-1-ynyl)-5-(pent-1,3-diynyl)- thiophene VIII; 2-(6-chloro-5- hydroxyhexa-1,3-diynyI)-5-(prop-1-ynyl)- thiophene IX; 2-(3,4-dihydroxybuta-1- ynyI)-5-(methyl)-dithiophene IX; 2-(3,4- dihydroxybuta-1-ynyiI)-5-(but-1,3-diynyI)- thiophene XI; 2-(4-chIoro-3- hydroxybuta- 1-ynyI)-5-(but-1,4-diynyl)-thiophene XII: C13- polyacetylenes; pentayne II and triyndiene III chromophores; methoxylated thymol derivatives XIII and XIV; humuIene XV

Pterocaulon cordobense Aerial parts: emmenagogue Aerial parts: antioxidant No data KURTZIANA Kuntze BAI, CHA, COR, COS, DFE, ERI, activity Ariza Espinar 1868 (CORD) FOR, LPA, SFE, SLU Pterocaulon lorentzii Malme Aerial parts: hepatic, cephalalgic, Aerial parts: antimicrobial No data Tuyá-canilla, frezadilla negra abluent activity Chiapella 1469 (CORD) BAI, CHA, COS, ERI, FOR, MIS, SFE, TUC

Pterocaulon polystachyum Aerial plants: depurative; against Dried aerial parts: Dried aerial parts. Chlorogenic acid: BARBOZA, G.E.etal.MedicinalfloraofArgentina DC. flies and fleas; against sunstroke antioxidant, amebicidal, and phenylpropanoid; ayapin, isoscopoletin, Hunziker 6530 (CORD) CHA, COS, ERI, FOR, MIS, SFE antifungal activity; radical prenyletin, prenyletin methyl ether, Yerba del toro, toroca á scavenging effect; larvicidal virgatenol, obtusinin, 5-methoxy-6,7- activity against Aëdes aegypti methylenedioxy coumarin, 5-(3,3- dimethylallyloxy)-6,7-methylenedioxy coumarin, 5-(2',3'-dihydroxy-3- methylbutanoxy)-6,7-methylenedioxy coumarin, haplopinol methyl ether, 6-(1,1- dimethyl-2-propenyl)-7-hydroxy coumarin and demethylnieshoutin, isovirgatenol, 3'- deoxyobtusinin, 6-methoxy-7-(2'- hydroxyethoxy)-coumarin, 5-(2'- hydroxyethoxy)-6,7-methylenedioxy coumarin, 5-hydroxy-6,7-methylenedioxy- 8-(3,3-dimethylallyl)-coumarin: coumarins Pterocaulon purpurascens Aerial parts: fungicidal Dried leaf: antibacterial Dried aerial parts. Purpurasol: Malme Root: alexipharmic activity coumarin; quercetagetin,3,7,4'-trimethyl Subils 4228 (CORD) CHA, COR, COS, ERI, FOR, JUJ, ether: flavonol SAL, SDE, SFE, TUC Pterocaulon rugosum (Vahl) Aerial plants: depurative No biological test Root. Tridec-1-ene-3,5,7,9,11-pentayne I; Malme CHA, COR, COS, ERI, MIS 2-(buta-3-en-1-ynyI)-5-(pent-1,3- diynyI)- Hunziker 18240 (CORD) thiophene IV; 2-(hexa-5-en-1,3-diynyl)-5- (prop-1-ynyI)-thiophene V; 2-(3,4- dihydroxybuta-1-ynyI)-5-(pent-1,3- diynyI)-thiophene VI; 2-(5,6- dihydroxyhexa-1,3-diynyl)-5-(prop-1- ynyl)-thiophene VII; 2-(4-chloro-3- hydroxybuta-1-ynyl)-5-(pent-1,3-diynyl)- thiophene VIII;2-(6-chloro-5- hydroxyhexa-1,3-diynyI)-5-(prop-1-ynyl)- thiophene IX; 2-(3,4-dihydroxybuta-1- ynyI)-5-(methyl)-dithiophene IX; 2-(3,4- dihydroxybuta-1-ynyiI)-5-(but-1,3-diynyI)- thiophene XI; 2-(4-chIoro-3- hydroxybuta- 1-ynyI)-5-(but-1,4-diynyl)-thiophene XII:

C13- polyacetylenes; pentayne II and 145 triyndiene III chromophores; methoxylated thymol derivatives XIII and XIV

Pterocaulon virgatum (L.) Aerial parts: hepatic, No biological test Dried aerial parts. Aromadendrin,7-O- 146 DC. emmenagogue, abluent, fungicidal (2-2-dimethyl-allyl): flavonoids; Tomo34(1-2):7-365.2009 Yacaraté-caá, tuya-cazo, yerba BAI, CAT, CHA, COR, COS, ERI, ayapin: coumarin; β-bisabolene: infiel, yerba de gato montes FOR, JUJ, SAL, SDE, SFE, TUC sesquiterpene; iso chlorogenic acid B: Ruiz de Huidobro 127 (LIL) phenylpropanoid; 5-(3-methyl-2- butenyl-oxy)-6-7-methylenedioxy coumarin, purpurasol,iso: coumarins Dried root. Thymohydroquinone dimethyl ether: monoterpene Schkuhria pinnata (Lam.) Dried entire plant, decoction: Dried aerial parts: antifungal, Fresh entire plant. 20-hydroxy Kuntze ex Thell. antibiotic; for stomach-ache; for antibacterial, and antimalarial chromolaenide, β-hydroxy-8-β-(4'-5'- Canchalagua, matapulgas, malaria, antidiabetic, anti- activity dihydroxy-tigloyl-oxy) costunolide,3: yerba de la pulga, inflammatory, diuretic, hepatic Leaf: anti-inflammatory activity sesquiterpenes; dithiin,3-(hex-1-3-diyn- canchalagua, manzanilla Dried branch + leaf, decoction: to 5-enyl)-6-(prop-1-ynyl): sulfur silvestre treat urinary and respiratory tract compound Ariza Espinar 3181 (CORD) infections, for acne Dried aerial parts. Leaf : depurative, to reduce weight, Schkuhripinnatolide A, B, C, antimicrobial, hypoglycemic chromolaenolide, eucannabinolide: Leaf + root: antiseptic, resolutive sesquiterpenes; heliangolides, BAI, CAT, CHA, COR, ERI, JUJ, pectolarigenin, germacranolide, LPA, LRI, MEN, NEU, RNE, schkuhrin II, santhemoidin A; SAL, SDE, SFE, SJU, SLU, TUC sitosterol, stigmasterol, α-amyrin, taraxasterol. Senecio bomanii R. E. Fr. Medicinal No biological test No data Cosillo CAT, JUJ, SAL, TUC Ariza Espinar 2649 (CORD) Senecio bonariensis Hook. Root: cicatrizant, abluent Dried entire plant: Dried root. Campesterol; daucosterol, & Arn. BAI, CHA, COR, COS, DFE, ERI, antimycobacterial activity sitosterol-3-O-β-D- Lengua de ciervo, lampago, SFE glucuronopyranoside: steroids; 10-α-

margarita del bañado, marga- (h): 6-β-iso-butyryl-oxy-9-oxo KURTZIANA rita de agua furanoeremophilane: sesquiterpene Hunziker 11164 (CORD) Senecio bracteolatus Hook. Part not specified: aromatic No biological test Dried aerial parts. 4-hydroxy & Arn. CHU, NEU, RNE, SCR Acetophenone: benzenoid; ascaridol: Charcao monoterpene; 1-β-hydroxy eudesma-4- Forcone 481 (CORD) 11-dien-3-one: sesquiterpene

Senecio brasiliensis (Spreng.) Leaf: rubefacient Inflorescence: antiulcer activity Dried aerial parts. Icyclogermacrene, BARBOZA, G.E.etal.MedicinalfloraofArgentina Less. Dried entire plant, decoction: Dried leaf: antimalarial activity 1-2-dehydro cacalol: sesquiterpenes; Primavera del campo, yerba febrifuge and for malaria brasilinecin: pyrrolizidine alkaloid de la primavera CHA, COS, MIS, SFE Essential oil. o-Cymene: monoterpene Pedersen 9214 (CORD) Fresh stem. Integerrimine: pyrrolizidine alkaloid Senecio clivicola Wedd. Entire plant: against muscular Leaf + stem: antileishmanial No data Amaicha, maicha, chilca, cramps activity huaycha Leaf + stem: antidiarrheal Ariza Espinar 2724 (CORD) JUJ, SAL Senecio cremeiflorus Mattf. Leaf: for infections No biological test No data Lampazo CAT, JUJ, SAL, TUC Ariza Espinar 2624 (CORD) Senecio crepidifolius DC. Aerial parts: for hernia and No biological test No data Árnica prolapse Novara 9081 (CORD) SAL Senecio deferens Griseb. Leaf: rheumatic pain, paye´s use No biological test Dried aerial parts. Retrorsine, Calzón roto CAT, FOR, JUJ, LRI, SAL, SDE, senkirkine, usaramine: pyrrolizidine Hunziker 17034 (CORD) TUC alkaloids Senecio eriophyton J. Rémy Plant: for montain sickness Aerial parts: antimicrobial and Essential oil. Isovaleric acid Chachacoma, chacha-coma Dried leaf: emmenagogue. relaxant activity fina LRI, MEN, SJU Bustos 38 (CORD) Senecio filaginoides DC. Medicinal No biological test Dried aerial parts. 4-hydroxy Mata mora, charcao, mata BAI, CAT, CHU, COR, LPA, LRI, Acetophenone: benzenoid; ascaridol: negra, mata rosa, romerillo, MEN, NEU, RNE, SAL, SCR, monoterpene; 1-β-hydroxy eudesma-4- altamisa, blanquillo, cosco, SJU, SLU, TDF, TUC 11-dien-3-one: sesquiterpene mata moro, mocoraca blanca, Dried flower + leaf + stem. vida-vida Furanoeremophil-1-one,10-β-(h): 6-α- Hunziker 23889 (CORD) acetyl-oxy: sesquiterpene Senecio fistulosus Poepp. ex Part not specified: anti- No biological test Dried entire plant. 10-β-h: 3-α- Less. var. fistulosus inflammatory, emollient, angeloxy-9-β-hydroxy-8-oxo Hualtata, lampazo, lengua de cardiotonic, diuretic, for mountain eremophilan-11-ene: sesquiterpene; vaca sickness senecionine: pyrrolizidine alkaloid Hollermayer 90 (CORD) MEN Dried leaf. Flavonol-3-7-O- diglycoside: flavonol Senecio fistulosus var. Part not specified: emollient, No biological test Dried aerial parts. Senecionine: ochroleucus (Hook. & Arn.) cardiotonic, diuretic pyrrolizidine alkaloid Cabrera CHU, MEN, NEU Dried leaf. Flavonol-3-7-o-diglycoside: 147 Hualtata flavonol Cabrera 6123 (LP)

Senecio leucostachys Baker Medicinal Aerial parts: molluscicidal Dried root. Integerrimine, senecionine, 148 Hunziker 4931 (CORD) BAI, CAT, COR, LPA, LRI, effects uspallatine: pyrrolizidine alkaloids MEN, NEU, RNE, SJU Tomo34(1-2):7-365.2009 Senecio nutans Sch. Bip. Part not specified: to treat Leaf + flowers + fruit: Aerial parts essential oil. α-terpinene, Chachacoma, chachacoma respiratory disorders, hypotensive, bacteriostatic effect; p-cymene, α- and β-pinene, neo-allo- del campo, chachacoma del cicatrizant, digestive, against bone antimicrobial and anti- ocimene, α- and β-phellandrene, cerro, tola, tola hembra, pain, and for mountain sickness hypertensive activity sabinene, α-terpinene, β-terpinene and chachacoma de la Puna, CAT, JUJ, LRI, SAL, TUC (sub nom. S. graveolens) γ-terpinene, 4-isopropylbencene, chachacoma del burro, Essential oil: antimicrobial and terpinolene, terpinen-4-ol, piperitenone, chachacoma hembra, choque anti-trypanosomal activity α- and β-eudesmol, cis-ascaridol, caña tricyclene, β-elemene, myrcene Senecio graveolens Wedd. Dried aerial parts. 4-hydroxy Hunziker 20884 (CORD) acetophenone: 3-(3'-hydroxy-iso-pentyl) acetophenone, 4-hydroxy-3-prenyl acetophenone: benzenoids; dihydroeuparin (sub nom. S. graveolens) Senecio oreophyton J. Rémy Part not specified: aromatic, Aerial parts: antimicrobial No data Chachacoma, sacha coma, cardiotonic, emmenagogue, activity yerba del incordio stimulant, stomachic Luján 66 (CORD) LRI, MEN, SAL, SJU Senecio pinnatus Poir. var. Leaf : cephalalgic, analgesic, Aerial parts: antimicrobial Dried leaf + stem. 10-α-(H) pinnatus alexipharmic activity Furanoeremophil-9-one: 1-α-hydroxy- Subils 626 (CORD) BAI, CAT, CHA, COR, COS, ERI, 6-α-angeloyl-oxy: sesquiterpene FOR, LPA, LRI, MEN, MIS, NEU, RNE, SDE, SFE, SJU, SLU, TUC Senecio pogonias Cabrera Part not specified: anti-ashmatic, No biological test No data Chachacoma blanca emmenagogue, cardio-active Beorchia 26 (CORD) MEN, SJU Senecio pseudotites Griseb. Leaf: diuretic, antiashmatic, No biological test Leaf. 2α, 3β, 23-trihydroxy-urs- Venturi 4801 (LIL) vermifugal 12,19(29)-dien-28-oic-acid; 2α, 3β, 23- Part not specified: vulnerary trihydroxy-urs-12,19(29)-dien-28-oic- trans p CAT, LRI, SAL, TUC acid-23-acetyl ester; 23-( - - KURTZIANA coumaroyloxy)-2α,3β trihydroxy-urs- 12,19(29)-dien-28-oic-acid: polyhydroxylated triterpenes; okanin 4- methyl ether 3’-O-β-D-(6’’- acetyl)glucopyranoside, okanin 4’-O-β- D-(3’’,4’’,6’’-riacetyl)glucopyranoside, okanin 4-methyl ether 3’-O-β-D- glucopyranoside: chalcones

Senecio puchii Phil. Parts not specified: stomachic, Aerial parts: antioxidant Aerial parts essential oil. Sabinene, α- BARBOZA, G.E.etal.MedicinalfloraofArgentina Cabrera 8380 (LP) hypotensive activity terpinene, γ-terpinene, p-cymene, CAT, JUJ, SAL terpinen-4-ol and β-pinene Senecio santelicis Phil. Medicinal Aerial parts: molluscicidal No data Chacha-coma CAT, JUJ, LRI, SAL, SJU effects; very toxic Hieronymus 305 (CORD) Senecio uspallatensis Hook. Part not specified: digestive No biological test Dried root. Retrorsine: pyrrolizidine & Arn. Dried root, infusion: substitute for alkaloid Chachacoma “mate” infusion Hunziker 11132 (CORD) MEN, SJU Senecio vira-vira Hieron. Part not specified: diaphoretic, No biological test Dried entire plant. α-amyrin: Vira-vira febrifuge, pectoral, emmenagogue, triterpene; anacrotine: pyrrolizidine Ariza Espinar 1956 (CORD) vulnerary alkaloid; eremophil-7(11)-en-12-8-α- BAI, CAT, COR, COS, ERI, olide,10-β-(H): 1-α-angeloyl-oxy: FOR, LPA, RNE, SDE, SFE, sesquiterpene SJU, SLU Senecio volckmannii Phil. Dried aerial parts, infusion: to No biological test No data Barboza 263 (CORD) treat shock Part not specified: expectorant, febrifuge CAT, JUJ, LRI, MEN, SAL, SJU, TUC Siegesbeckia serrata DC. Part not specified: treatment No biological test No data Ariza Espinar 3443 (CORD) wounds and burns, rheumatism, renal colic, syphilis, leprosy and various skin diseases CAT, COR, JUJ, LRI, SAL, TUC Smallanthus macroscyphus Root: urinary and hepatic disorders No biological test Aerial parts. (6R*, 7S*, 8S*, 9S*)-8- (Baker) A. Grau JUJ, SAL, TUC Hydroxy-9-methacryloxy-10- Yacón del campo carbomethoxymelampo-1(10),4,11(13)- Novara 7846 (CORD) trien-6,12-olide, (6R*, 7S*, 8S*, 9S*)- 8-Hydroxy-9-angeloxy-10- carbomethoxymelampo-1(10),4,11(13)- trien-6,12-olide, (4S*, 5S*, 6R*, 7R*, 8S*, 9S*)-4,5-Epoxy-8-hydroxy-9- angeloxy-10-carbomethoxy-melampo- 1(10),11(13)-dien-6,12-olide: 149 melampolides

150 Solidago chilensis Meyen Dried aerial parts: digestive, anti- Essential oil: antimicrobial and Dried rhizome. Caryophyllene-1-10- var. chilensis gonorrhea antioxidant activity epoxide: sesquiterpene; matricaria ester: Tomo34(1-2):7-365.2009 Romerillo amarillo, virga Root + flowers: cephalalgic, sedative Rhizome: anti-inflammatory alkenyne C5 or more; caffeic acid and áurea, vara amarilla, vara de Leaf: diaphretic, anti-lithic activity 5-O-caffeoylquinic acid oro, mbiug, cola de zorro, Dried flowers, infusion: diuretic Dried root. Junceic acid: diterpene; yuyo de San Juan, Yerba de BAI, CAT, CHA, CHU, COR, quercetin-3-O-α-l-galactoside: flavonol Santa María COS, ERI, JUJ, LPA, LRI, MEN, Essential oil. Pumiloxide: labdane Ariza Espinar 2808 (CORD) MIS, NEU, RNE, SAL, SCR, diterpene; limonene, γ-cadinene: SDE, SFE, SJU, SLU, TUC sesquiterpenes Symphyotrichum Aerial parts: antidiarrheal, Aerial parts (stem + leaf + Dried flowers. α-Amyrin: triterpene; β- squamatum (Spreng.) stomachic, anti-ulcer, cicatrizant, fruit): antiulcer and gastric acid sitosterol: steroid; flavonoids, G.L.Nesom antineoplasic antisecretory activity phenols, aminogroups, saponins, Rama negra Dried entire plant, decoction: (sub nom. A. squamatus var. tannins Aster squamatus (Spreng.) against enteritis squamatus) (sub nom. A. squamatus var. Hieron. var. squamatus (sub nom. A. squamatus var. squamatus) Subils 615 (CORD) squamatus) BAI, CAT, CHA, CHU, COR, COS, ERI, FOR, JUJ, LRI, MEN, MIS, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC argentina Cabrera Aerial parts: diuretic, digestive No biological test Flower. Myricetin derivatives Burkart 20425 (CORD) COR, MEN, SJU, SLU, TUC Tagetes campanulata Dried entire plant, infusion: for Leaf + flower: antioxidant Seedling. Bithienyl,2-2': 5-(4-acetoxy- Griseb. stomach pains, cardiotonic, activity 1-butynyl), terthienyl, α: sulfur Rosa amarilla, suico vaca, stimulant compound suico, suiquillo CAT, JUJ, LRI, SAL, SJU, SLU, Leaf. Quercetin 3-O-diglucoside, Hunziker 19875 (CORD) TUC quercetin 3-O-glucoside, luteolin, luteolin 7-O-glucoside, quercetagetin 3,5,6,7,3’-pentamethyl ether, quercetagetin 3,6,3',4'-tetramethyl ether: flavonoids Flower. Quercetagetin, quercetagetin 7- KURTZIANA O-glucoside, quercetagetin 3-O- g1ucoside, quercetin, quercetin 3-O- diglucoside, patuletin and patuletin 7- O-glucoside: flavonoids

BARBOZA, G.E.etal.MedicinalfloraofArgentina Tagetes filifolia Lag. Aerial parts: carminative, digestive, Dried aerial parts: sweetening Fresh entire plant. Estragole: Anís del campo, anís de la antispamodic, for infectons, neonatal effect; antibacterial, antiviral, phenylpropanoid sierra, anisillo, suico vaca, and paediatrics care, used in antispasmodic, and anti-tumor Root. Bithienyl,2-2': 5-(4-acetoxy-1- anicillo, anís, anís anís, anís del pregnancy and facilitate birth, post activity butenyl): sulfur compound cerro, chincoco, anís silvestre, partum pains and diseases; decoction: Leaf. Quercetagetin, quercetagetin 7- cominillo, roco, pampanis febrifuge and for cough Gl, quercetagetin 7-Ar-Gal, Tagetes multifida DC. CAT, COR, JUJ, SAL, SLU, TUC quercetagetin 3-Ar-Gal, patuletin 7-Gl, Tagetes pusilla Kunth isorhamnetin (sub nom. T. multifida) Subils et al. 3901 (CORD) Essential oil. : phenylpropanoid; trans anethole: phenylpropanoid; limonene, citral, tagetone: monoterpenes Tagetes mendocina Phil. Part not specified: stimulant Dried entire plant: antibacterial Aerial parts. 4’-hydroxyacetophenone, Quinchihue, chil-chil de la stomachic, aphrodisiac and antioxidant activity protocatechuic acid, syringic sierra CAT, LRI, MEN, SJU, SLU acid, patuletin, quercetagetin 7-O-β-D- Ariza Espinar 1750 (CORD) glucoside, patuletin 7-O-β-D-glucoside, axillarin 7-O-β-D-glucoside Tagetes minuta L. Entire plant, decoction: Leaf + flowers: antitumor, Flowering tops. β-myrcene, p-cymene, Chinchilla, suico, suique, chil antiabortive antiviral, and antimicrobial limonene, (Z) ocimene, (E) ocimene, chil, margarita, floramar Aerial parts: carminative, activity dihydro-tagetone, γ-terpinene, cis- Subils 3889 (CORD) digestive, antispamodic, diuretic, Root: pheromone linalool oxide, dimethyl styrene, trans- antimicrobial, antifungal, Aerial parts essential oil: para-Menth-2-en-1-ol, linalool, α- anthelmintic, antiseptic, hypotensive, bronchodilatory, thujone, cis-sabinene hydrate, camphor, antitussive, pectoral, against the spasmolytic, anti-inflammatory, trans-tagetone, cis-tagetone, cis- pediculosis and the alopecia, and pinanone, 4-terpinenol, cis-dihydro abluent; infusion: anthelmintic, antidepressant activity carvone, Eschscholtzia ketone, disinfectant, fungicide, for verbenone, citronellol, cis-carveol, cis- infections, neonatal and paediatrics ocimenone, trans-ocimenone, para- care, used in pregnancy and Anisadldehyde, linalyl acetate, methyl facilitate birth, post partum pains citronellate, trans-anethole, dehydro and diseases Eschscholtzia ketone, tridecane, δ- Dried branch + leaf, decoction: to elemene, neryl acetate, trans-isosafrole, treat urinary tract infections β-patchoulene, geranyl acetate, 151

Tagetes minuta L. Leaf + flowers: infusion: tetradecane, methyl eugenol, 152

(continuation) antihysteric, diaphoretic, caryophyllene, aromandrene, α- Tomo34(1-2):7-365.2009 aphrodisiac, bitter beverages, humulene, γ-ionone 6 methyl, against venereal disease valencene, α-muurolene, n-pentadecane, BAI, CAT, CHA, COR, COS, ERI, β-bisabolene, γ-cadinene, δ-cadinene, FOR, JUJ, LPA, LRI, MEN, MIS, wugenyl acetate, γ-elemene, ledol, SAL, SDE, SFE, SJU, SLU, TUC spathulenol, guaiol, alchenenotiol, methyl linoleate, methyl stearate, docosan-7-9-dione, pentacosane, heptacosane, methyl heptacosane, octacosane, methyl nonacosane, triacontane, hentriacontane, dotriacontane, tritriacontane, pentatriacontane, heptatriacontane Leaf. Quercetagetrin, patuletrin, quercetagetrin-7-arabinosyl- galactoside: flavonoids Leaf essential oil. p-cymene, limonene, (Z) ocimene, (E) ocimene, dihydro- tagetone, artemisia ketone, chrysantenone, (E) tagetone, myrcenone, (Z) tagetone, borneol, p- Mentha-1,5-dien-8-ol, santalone, (Z) ocimenone, (E) ocimenone, carvone, thymol, isopiperitenone, piperitenone, (E-E) α-farnesene, spathulenol Root. 2-2' 5-(4-acetoxy-1-butenyl) bithienyl : sulfur compound Fresh fruit essential oil. Nor Bornane: 2-iso-butyl, carvone, jasmolin I, p-

cymene, (Z) ocimene, dihydro-tagetone, KURTZIANA nopinone, (E) tagetone, myrcenone, (Z) tagetone, borneol, p-Mentha-1,5-dien-8- ol, santalone, (Z) ocimenone, (E) ocimenone, carvone, piperitenone, spathulenol Oil seed. Sterols, phospholipids, proteins, lysine, sugars (glucose), P, Ca

BARBOZA, G.E.etal.MedicinalfloraofArgentina Tagetes multiflora Kunth Aerial parts: cardiotonic, No biological test No data Suico, suico-vaca stimulant Negritto 391 (CORD) CAT, JUJ, LRI, SAL, TUC Tagetes terniflora Kunth Branches, leaf and flowers: Aerial parts essential oil: Aerial parts essential oil. Trans- Suico, margarita, suico-suico against cough, colds, fever, toxicity activity tagetone, (E)-β-ocimene; ocimenones; Hunziker 19109 (CORD) diarrhea, dyspepsia, and partutition Leaf: antibacterial activity limonene, isomenthone, spathulenol: hemorrhage sequiterpenoids; cis- and trans- CAT, JUJ, SAL, TUC Anethole: phenylpropanoids Tessaria absinthioides Leaf: hypocholesterolemiant, Aerial parts: anti-inflammatory Dried aerial parts. 3-β-5-α-dihydroxy (Hook. & Arn.) DC. balsamic, expectorant activity costic acid , eremophilane (tessaric Pájaro bobo, chilca, suncho Dried aerial parts, infusion: to Leaf: antitumor activity acid): sesquiterpene; thiophene,2-(but- rosado, brea, suncho negro lower cholesterol Aerial parts essential oil: 3-en-1-ynyl)-5-(penta-1-3-diynyl): Ariza Espinar 1598 (CORD) BAI, CAT, CHU, COR, JUJ, LPA, virucidal activity sulfur compound; casticine, artemisine, LRI, MEN, NEU, RNE, SAL, SJU, chrysosplenetine: flavonoids SLU, TUC Tessaria ambigua DC. Part not specified: antitussive, No biological test Aerial parts. α-amyrine, penduletin, Pájaro bovo hepatic, tonic, depurative, laxative 3,6,7-O-trimethyl quercetagetin, Ariza Espinar 1595 (CORD) BAI, CAT, CHA, COR, COS, FOR, artemisine JUJ, LRI, SAL, SDE, SFE, TUC Tessaria dodoneifolia Leaf: abortifacient, vaginal No biological test Dried leaf+ stem. Tedonodiol: (Hook. & Arn.) Cabrera mycosis, anuria, urin with blood, sesquiterpene; eriodyctiol, sakuranetin, Chilca dulce, suncho, chilca, emmenagogue luteolin, 7-O-methyleriodyctiol, 4’,7-O- chilca negra, suncho BAI, CAT, CHU, COR, JUJ, LPA, dimethylnaringenin, dihydroquercetin- Ariza Espinar 2343 (CORD) LRI, MEN, NEU, RNE, SAL, SJU, 3-acetate, 3-O-methyl-quercetin, 3,6-O- SLU, TUC dimethylquercetagetin: flavonoids Tessaria integrifolia Ruiz & Dried entire plant, infusion: Dried aerial parts: radical Aerial parts. α-amyrin: acetate: Pav. diuretic and for asthma scavenging effect; anti- triterpene; artemisine, casticine: Aliso del río, aliso, aliso Leaf, decoction: febrifuge; infusion: inflammatory and antimicrobial flavonoids; 3-4-di-O caffeoyl-quinic bobo, bobo, buibé, pájaro for asthma, astringent, cicatrizant activity acid, iso chlorogenic acid a,: methyl bobo, palo bobo Leaf + flowers: antigonorrheal, ester: phenylpropanoid; 3,5-O-di- Hosseus 91 (CORD) antiallergic, antiasthmatic, anti- caffeoyl-quinic acid. 4,5-O-di- caffeoyl- inflammatory, diuretic quinic acid BAI, CHA, COS, ERI, FOR, JUJ, Dried leaf. Iso chlorogenic acid b:

MIS, SAL, SFE, TUC phenylpropanoid; cuauthemone-3-O-(3- 153 methyl-valerate): sesquiterpene

Thelesperma Leaf: digestive, antispamodic, Aerial parts: antibacterial and Entire plant. Cynaroside, luteolin: 154 megapotamicum (Spreng.) against kidney diseases. antioxidant activity flavone Kuntze BAI, COR, ERI, LPA, MEN, Dried aerial parts. Tomo34(1-2):7-365.2009 Té pampa, té indio NEU, RNE, SDE, SFE, SLU Thymohydroquinone dimethyl ether: Ariza Espinar 3353 (CORD) monoterpene Dried root. 4-0-iso-butyryl-3-0-methyl- 7-8-epoxy coniferyl acetate: phenylpropanoid Thymophylla pentachaeta Aerial parts: digestive, diuretic Aerial parts: antioxidant and No data var. belenidum (DC.) BAI, CAT, COR, LPA, LRI, antifungal activity Strother MEN, NEU, RNE, SAL, SDE, Yerba amarilla SJU, SLU Saravia Toledo 973 (MCNS) Trichocline auriculata Part not specified: stomachic, No biological test No data (Wedd.) Hieron. othalgic Achicoria, café del campo, JUJ, SAL contrayerba, negro-ampe, papaballa Cialdella 479 (SI) Trichocline boecheri Part not specified: alexipharmic No biological test No data Cabrera MEN, SJU Contrayerba Bustos et al. (CORD 165) Trichocline cineraria (D. Part not specified: stomachic No biological test No data Don) Hook. & Arn. MEN, SJU Contrayerba macho Biurrun et al. 5761 (CORD) Trichocline dealbata (Hook. Part not specified: stomachic No biological test No data & Arn.) Benth. & Hook. f. ex MEN, NEU Griseb. Contrayerba, yerba corro, KURTZIANA yerba del corro Kuntze 103 (CORD) Trichocline macrocephala Part not specified: antinephritic Aerial part: antinociceptive No data Less. MIS activity Cravo do campo Root: antioxidant activity Maruñak 116 (LP)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Trichocline plicata D. Don Root: to relieve the stomachache No biological test No data ex Hook. & Arn. COR, SLU Topasaire plateado, contra- hierba, yerba del corro Cocucci 320 (CORD) Trichocline reptans (Wedd.) Root: stomachic, to relieve Aerial parts: antioxidant Dried aerial parts. 6-acetyl-5- Hieron. gastrointestinal disorders, activity hydroxy-2-iso-propenyl 2-3-dihydro Arnica, contrahierba, coro, diaphoretic benzofuran oxygen heterocycle; yerba china, yerba del ciervo BAI, CAT , CHA, COR , JUJ, imperatorin: coumarin Ariza Espinar 2843 (CORD) LPA , LRI, MEN, RNE , SAL, SDE , SFE, SJU, TUC Trichocline sinuata (D. Root: stomachic, diaphoretic No biological test Dried aerial parts. 6-acetyl-5- Don) Cabrera BAI, COR, ERI, LPA, RNE, SFE, hydroxy-2-iso-propenyl 2-3-dihydro Árnica del campo, maravilla, SLU benzofuran: oxygen heterocycle; yerba china bergapten, phellopterin: coumarin Hunziker 18951 (CORD) Trixis cacaloides (Kunth) D. Part not specified: diaphoretic No biological test Dried aerial parts. Don CAT, CHA, COR, COS, LPA, α-amyrin, taraxasteryl acetate: Coca, inga-inga LRI, MEN, SAL, SDE, SJU, SLU, triterpene; β-sitosterol: steroid; trixis Kurtz 2635 (CORD) TUC sesquiterpene 4: sesquiterpene; isocedrene derivatives Trixis divaricata subsp. Entire plant, infusion: for No biological test No data discolor (D. Don) Katinas amenorrhea, to treat diabetes; for Contrayerba humoral and blood diseases; Ariza Espinar 3350 (CORD) decoction: emmenagogue; against insects, spiders and snakebites, abortifacient Root: against cough, colds Leaf: vulnerary, abluent, rubesfacient, diaphoretic, diuretic, antirheumatic Flowers: anti-inflammatory CAT, CHA, COR, ERI, FOR, LRI,

SFE, SJU, SLU 155

156 Trixis pallida Less. Root: anthelmintic No biological test Aerial parts. Contrayerba, urusú catí CHA, COS, ERI, FOR, MIS (2S,3S,4S,6R,7R,9R,10R,11R,14S)-3- Tomo34(1-2):7-365.2009 Cocucci 3042 (CORD) Acetyloxy-9-hydroxy- 14-(erythro-2-methyl-3- acetyloxybutanoyloxy)-14,15- epoxytrix- 5(15)-en-4,12-olide, 3-Acetyloxy-9- hydroxy-14-(erythro-2-methyl-3- hydroxybutanoyloxy)-14,15-epoxytrix- 5(15)-en-4,12-olide, 3-Acetyloxy-9- hydroxy-14-(threo-2-methyl-3- hydroxybutanoyloxy)-14,15-epoxytrix- 5(15)-en-4,12-olide, 3-Acetyloxy-9- hydroxy-14-(3-hydroxy-3- methylbutanoyloxy)- 14,15-epoxytrix- 5(15)-en-4,12-olide, 3-(3- Methylbutanoyloxy)-9-hydroxy-14- (threo-2-methyl-3- hydroxybutanoyloxy)-14,15-epoxytrix- 5(15)-en-4,12- olide, 3-(2-Methylbutanoyloxy)-9- hydroxy-14-(threo-2-methyl- 3-hydroxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3-(3- Methylbutanoyloxy)-9-hydroxy-14- (erythro-2-methyl- 3-hydroxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3-(threo- 2-Methyl-3-acetyloxybutanoyloxy)-9- hydroxy-14-(erythro-2-methyl-3- acetyloxybutanoyloxy)-14,15- KURTZIANA epoxytrix-5(15)-en-4,12-olide, 3-(3- Methyl-3-acetyloxybutanoyloxy)-9- hydroxy-14-(erythro-2-methyl-3- acetyloxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3-(3-

Trixis pallida Less. Hydroxy-3-methylbutanoyloxy)-9- BARBOZA, G.E.etal.MedicinalfloraofArgentina (continuation) hydroxy-14-(erythro-2-methyl-3- acetyloxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3-(2- Methylbutanoyloxy)-9-hydroxy-14- (erythro-2-methyl-3- acetyloxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,-12-olide, 3-(3- Methylbutanoyloxy)-9-hydroxy-14- (erythro-2-methyl- 3-acetyloxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,-12-olide, 3-(3- Hydroxy-3-methylbutanoyloxy)-9-(2- methylbutanoyloxy)-14-(erythro-2- methyl-3-hydroxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3-(3- Hydroxy-3-methylbutanoyloxy)-9-(2- methylbutanoyloxy)-14-(threo-2- methyl-3-hydroxybutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide, 3,14- Bis(3-hydroxy-3-methylbutanoyloxy)- 9-(2-methylbutanoyloxy)-14,15- epoxytrix-5(15)-en-4,12-olide: trixanolides Urmenetea atacamensis Part not specified: hypertension, No biological test Dried aerial parts. Lupeoyl acetate, Phil. mountain sickness lupeol: triterpenes Cotaro, coquilla, cótar CAT, JUJ, SAL Cabrera & Schwabe 80 (LP) Verbesina encelioides (Cav.) Aerial parts, infusion: cicatrizant Dried aerial parts: toxic effect; Dried entire plant. α-amyrin: Benth.& Hook. f. ex A. Gray Leaf: hemostatic, to relieve antibacterial activity triterpene; campesterol: steroid; Santa María, suncho, mira- bruises, vulnerary, for skin daucosterol: steroid; galegine: alkaloid- solcito disorders misc; linoleic acid: lipid Ariza Espinar 2760 (CORD) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS,

NEU, RNE, SAL, SDE, SFE, SJU, 157 SLU, TUC

158 Vernonia chamaedrys Less. Root: emmenagogue No biological test Plant. Apigenin, luteolin 7-methyl Escoba dura, pichana, pugno, CHA, COS, ERI, FOR, MIS, SFE ether, luteolin 3’-methyl ether, luteolin Tomo34(1-2):7-365.2009 quiebra arado 7, 3’-dimethyl ether: flavonoids Hunziker 5326 (CORD) Vernonia cincta Griseb. Leaf: for scabies No biological test No data Dematteis 522 (CTES) Flower/sap: eye infection CAT, FOR, JUJ, SAL, TUC Vernonia cognata Less. Medicinal No biological test Dried aerial parts. α amyrin, β amyrin: Cocucci 2990 (CORD) CHA, COS, ERI, FOR, MIS, SFE triterpene; glaucolide B, piptocarphol diesters Dried leaf. Germacrene D: sesquiterpene; taraxasterol: triterpene Vernonia flexuosa Sims var. Medicinal No biological test Aerial parts. Apigenin 7-methyl ether, flexuosa BAI, CHA, COR, COS, ERI, FOR, luteolin 7, 3’-dimethyl ether: flavonoids Quiebra arado MIS, SDE, SFE Root. Vernoflexin: sesquiterpene Hunziker 2192 (CORD) Vernonia mo llisima D. Don Leaf: diaphoretic No biological test Aerial parts. Sesquiterpene, triterpene ex Hook. & Arn. BAI, COR, COS, ERI, MIS, SFE Hunziker 7245 (CORD) Vernonia niederleinii Hieron. Aerial parts: for burns No biological test No data Planta del fuego COS, MIS Cabrera 29054 (SI) Vernonia scorpioides (Lam.) Plant: treatment of allergies, skin Aerial parts: immuno- Dried aerial parts. Germacra-1(10)- Pers. parasites, skin injures and itching, modulatory and cytotoxic trans-4-trans-dien-15-oic acid-12-8-α- Ariza Espinar 2300 (CORD) antiseptic activity olide, glaucolide A: sesquiterpene Part not specified, infusion: Leaf: cicatrizant activity Essential oil. δ-cadinene: sesquiterpene stimulant, aphrodisiac BAI, CHA, COS, ERI, FOR, MIS, SFE KURTZIANA Vernonia squamulosa Hook. Medicinal Dried leaf + stem: Dried aerial parts. α amyrin, β amyrin: & Arn. CAT, JUJ, LRI, SAL, TUC antileishmanial activity triterpene; glaucolide A, piptocarphin Santa Rosa, suncho negro, A: sesquiterpene guadalupe Hunziker 5175 (CORD)

Vernonia tweedieana Baker Leaf: expectorant Leaf: antioxidant activity Aerial parts. α-and β-amyrin, lupeol, BARBOZA, G.E.etal.MedicinalfloraofArgentina Mata campo COS, FOR, MIS Root: antibacterial and cytotoxic palmitic acid Tressens 6172 (CTES) activity Leaf. α- and β-amyrin, lupeol: triterpenes; β-sitosterol, stigmasterol, spinasterol: steroids; eriodictyol: flavanone Root. Lupenyl palmitate and a mixture of α-and β-amyrin palmitate Wedelia subvaginata N.E. Medicinal Aerial parts: molluscicidal No data Br. CHA, COS, ERI, FOR, SFE effects Pire 6773 (CORD) Werneria heteroloba Wedd. Part not specified: anti- No biological test No data Pupusa de vega inflammatory, antispasmodic Cabrera 9049 (LP) CAT, JUJ, SAL, TUC Xanthium ambrosioides Aerial parts: allergenic, No biological test No data Hook. & Arn. respiratoy disorders, antinephritic, Abrijo de vizcachera, cadillo, hepatic, vulnerary, antispamodic, roseta, abrojo chico abluent, astringent,stomachic, for Hunziker 8836 (CORD) treating wounds externally, hemostatic, anti-inflammatory, ophtalmic, for vaginal infections BAI, CAT, COR, LPA, MEN, NEU, RNE, SLU Xanthium catharticum Dried entire plant, infusion: for Dried aerial parts: antibacterial Dried root. Lasidiol para-methoxy- Kunth stomach pains and antitrypanosomal activity benzoate: sesquiterpene Espinillo Dried root, infusion: stimulant Root + stem: antileishmanial Burkart 6403 (BA) CAT, CHU, JUJ, NEU, RNE, activity SCR, SJU Xanthium cavanillesii Aerial parts: antispamodic, Aerial parts: antimicrobial Aerial parts essential oil. Camphene: Schouw purgative, abluent, against activity; antiulcer and monoterpene; δ-cadinene: Abrojo, abrojo grande, abrojo disorders respiratory, nephritic, gastroprotection agent sesquiterpene; para cresol: benzenoid macho hepatic, antispamodic, vulnerary Aerial parts. Xanthatin, 24- Hunziker 11556 (CORD) Fruit: oxitoxic, to ease birth mehylenecycloartanol, lupeol, β- amyrin, stigmasterol, campesterol, sitosterol, loliolide and several 159 xanthanolides.

Xanthium cavanillesii Seed + root: antidysenteric, diuretic 160

Schouw Dried seed, decoction: to treat Tomo34(1-2):7-365.2009 (continuation) urinary tract infections BAI, CAT, CHA, COR, COS, ERI, FOR, LPA, MEN, MIS, RNE, SAL, SFE, SJU Xanthium spinosum L. var. Entire plant: choleretic, hepatic, Dried leaf: insulin degradation Dried aerial parts. 3'-4'-didesulfated spinosum laxative, diuretic, antidysenteric, inhibition; antimicrobial and atractyloside: diterpene; caffeic acid, Cepa caballo, abrojo chico, antispamodic, antiseptic, antitumor activity chlorogenic acid, coniferyl alcohol: abrojito, abrojillo, abrojo, cephalalgic, antimicrobial, Leaf + stem: antitumor activity phenylpropanoids; douglanin: abrepuño, abrojo duro, contraceptive, calmative, depurative sesquiterpene; quercetin, 8-(γγ- jadillo, tepaia, Aerial parts, infusion: decongestive, dimethylallyl) apigenin: flavonoids; Ariza Espinar 2809 (CORD) antiseptic, antispasmodic and for xanthanol,deacety l: 2-acetoxy-4- malaria; against diarrhea; decoction: hydroxy: sesquiterpene; xanthatin, maturating xanthinine, stizalicine, solsititialin: Leaf + flowers: cholagogue, sesquiterpene lactones laxative, antigonorreea Dried leaf, infusion: diuretic Root: digestive, hepatic BAI, CAT, CHA, CHU, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC Xenophyllum incisum Aerial parts: hepatic, No biological test Aerial parts essential oil. α-and β- (Phil.) V.A. Funk var. antirheumatic, altitude sickness pinene, myrcene, α- and β- incisum JUJ, SAL phellandrene, p-cymene, limonene, Pupusa de río, pupusa de nopinone, trans-pinocarveol, agua, pupusa del cerro pinocarvone, cryptone, myrtenol, Cabrera 8623 (LP) myrtenal, α-copaene, α-humulene, α- and γ-muurolene, α- and β-selinene, γ-

cadinene, cis-calamenene, α-calacorene, KURTZIANA α-cyperone, β-dihydroagarofurane; 2,2- dimethyl-6-acetyl-3-chromene, 6- hydroxytremetone, euparin: p- hydroxyacetophenone derivatives; incisol (incisa-3 (E), 6(14), 11-trien-9α- ol)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Xenophyllum poposum Branches + leaf: against diarrhea Aerial parts: anti-hypertensive Aerial parts essential oil. α- and β- (Phil.) V. A. Funk and gastrointestinal bloating, for activity pinene, β-phellandrene, terpinen-4-ol, Pupusa, poposa, llareta, pupu- mountain sickness (sub nom. W. poposa) α-terpinene, citronelal, isopulegone, Δ sa de la ciénaga Part not specified: against abdominal 3-carene, 1,8-cineol, nerolidol, other Werneria poposa Phil. pain, flu, indigestion, intestinal sesquiterpenes Cabrera 9093 (LP) inflammation, rheumatism, soroche Plant. 2R-(-)-6-hydroxytremetone (altitude sickness) and to stabilize (sub nom. W. poposa) arterial pressure JUJ, SAL, TUC Zexmenia brachylepis Aerial parts: against aphtha, No biological test No data (Griseb.) Cabrera hepatic affections, to avoid Pante amarillo, saitilla vomiting Krapovickas 46814 (CTES) CHA, FOR, JUJ, SAL, SDE, TUC Zinnia peruviana (L.) L. Leaf: antimalarial, febrifuge Dried aerial parts: antifungal Aerial parts. 6-β-acetoxy-9-α- Flor de papel, yerba de San Ja- CAT, CHA, COR, ERI, FOR, JUJ, and antibacterial activity angeloyl-oxy-15-oxo elemanolide , cinto, clavelillo, chinita del cam- LPA, LRI, MEN, SAL, SDE, SJU, germacrene D, zinaflorine II, III: po, clavel del campo, chinita SLU, TUC sesquiterpenes ______Ariza Espinar 2943 (CORD)

161

162 BALANOPHORACEAE Lophophytum leandri Eichl. Rhizome: hepatic, diuretic No biological test Rhizome. Naringenin, eriodyctiol, Tomo34(1-2):7-365.2009 Flor de piedra COS, MIS quercetin: flavonoids Grondona 1709 (SI) Ombrophytum Rhizome: digestive, urinary No biological test No data subterraneum (Aspl.) B. disorders Hansen CAT, JUJ, SAL, TUC Ancañoca, ankañoca, aspa- loro, hichar, hicharejo, ichar Barboza 1340 (CORD) BASELLACEAE Anredera cordifolia (Ten.) Entire plant, infusion: Dried leaf: antibacterial activity Dried entire plant. Steroids Steenis antidiarrheal, for arthritis, for burns Brotal, papa santa, hierba Aerial parts: pectoral, ophtalmic santa, Santa Lucía, Santa Dried leaf: antineuralgic, eye washes, María, Santa Rita, enredadera neonatal and paediatrics care; for skin de papa, enredadera del affections (mycosis, warts, insects mosquito, papa del diablo, bite, itching, irritation) zarza, suelda, papilla BAI, CAT, CHA, COR, COS, Subils 2378 (CORD) DFE, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, SLU, TUC Ullucus tuberosus subsp. Tuber: medicinal Fresh tuber: antihyperglycemic Entire plant. Tuberoside A, tuberoside aborigineus (Brücher) Dried tuber, infusion: for activity B, tuberoside C: triterpenes Sperling headache Ulluco, papa lisa, papa chola, Fresh tuber: antidiabetic melloca, ulluma, papa verde, JUJ ruba Brücher 3015 (VEN) BEGONIACEAE Begonia cucullata Willd. Aerial parts: refrigerant, antitussive, No biological test No data KURTZIANA var. cucullata antiscorbutic, diuretic, purgative, Agrial antisyphilitic, astringent, vulnerary, Arbo 7874 (CTES) for conjunctivitis, febrifuge Fresh root: for toothache pain COS, MIS

Begonia cucullata var. Leaves: rubefacient, vulnerary, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina spatulata (Lodd.) Golding antitussive, diuretic, antiscorbutic, Zuloaga 6664 (SI) anti-inflammatory BAI, CHA, COS, ERI, JUJ, MIS Berberis darwinii Hook. Entire plant: anti-inflammatory, No biological test Dried stem. Andesine: indole alkaloid; Calafate tonic berberine, 1-O-methyl chitraline: Chiapella 1800 (CORD) CHU, NEU, RNE, TDF isoquinoline alkaloid; isoindolinone derivatives; nuevamine: isoindoloisoquilinone alkaloid; lennoxamine: isoindolobenzazepine Dried fruit. Delphinidin-3-glucoside: flavonoid Berberis empetrifolia Lam. Plant: mountain sickness No biological test Plant. (±)-chilenine, lennoxamine, Calafatillo, calafate chico, Root: digestive, antidiarrheal coyhaiquinine, natalimine, puntarenine: michay, calafate enano, zar- CAT, CHU, LRI, MEN, NEU, isoquinoline alkaloids; berberine: cilla, uva de la cordillera, RNE, SCR, SJU, TDF protoberberine alkaloid; benzyl- and monte negro bisbenzyl-isoquinoline alkaloids Barboza 1211 (CORD) Berberis grevilleana Gillies Root: for dyspepsia, anorexia, No biological test No data ex Hook. & Arn. decongestant, hepatic, antipyretic Guaglianone 1553 (SI) COR, MEN, SJU Berberis lilloana Job Root: fegrifuge, cholalogue, No biological test No data Sacha uva antidiarrheal, for heart treatments Cocucci 2079 (CORD) and tumours CAT, JUJ, SAL, TUC G. Part not specified: antipyretic, for Shoots: antimicrobial activity Dried entire plant. Chillanamine: Forst. cold, toxic (sub nom. B. buxifolia) isoquinoline alkaloid; chiloenamine, Calafate Dried bark, decoction: for urinary Leaf + stem : antifungal activity chiloenamine A, B, chiloenine: amine Berberis buxifolia Lam. and respiratory tract infections (sub nom. B. heterophylla) alkaloids; calafatamine, calafatine, Berberis heterophylla Juss. Leaf + stem, decoction: for Part not specified: antiviral calafatine 2-α-Noxide, calafatine 2-β-N- ex Poir. stomachache and other intestinal activity oxide, curacutine, (-)-osornine, (-)- Bernardello 593 (CORD) irritations talcamine: bisbenzylisoquinoline alkaloids. (sub nom. B. buxifolia Lam.) Fruit. Berberine, berberidine, Fruit: astringent, digestive, oxycanthine: alkaloids; tannins, antidiarrheal , resins, starch, malic acid Root: antidiarrheal, astringent, (sub nom. B. buxifolia) febrifuge, digestive, hepatic, anti- Dried root. Argemonine, berberine: inflammatory, tonic isoquinoline alkaloid 163 (sub nom. B. buxifolia Lam.) (sub nom. B. buxifolia) CHU, NEU, RNE, SCR, TDF

164 Berberis montana Gay Bark + root: for digestive No biological test No data Palo amarillo disorders Tomo34(1-2):7-365.2009 Cabrera 21913 (SI) NEU, RNE Berberis ruscifolia Lam. Entire plant: eupeptic, hepatic, Root: antimalarial activity Dried leaf. Hyperoside: flavonol; Calafate, quebrachillo, palo anti-inflammatory, febrifuge luteolin: flavone; hydrocarbons, amarillo, sacha uva, uvilla Root: antimalarial, hypotensive alcohols, sterols, anthocyanins Hunziker 11292 (CORD) Leaf + stem: hepatic, anti- inflammatory, antimalarial BAI, CAT, CHA, CHU, COR, COS, ERI, LPA, LRI, NEU, SDE, SFE, SLU Berberis trigona Kunze ex Entire plant: anti-inflammatory, Leaf + stem: cytotoxic activity No data Poepp. & Endl. tonic (sub nom. B. linearifolia) Berberis linearifolia Phil. NEU, RNE Michay Hosseus 1045 (CORD) BETULACEAE Alnus acuminata Kunth Bark: for sealing wounds, rashes, Aerial parts: antibacterial Leaf. Sterols, triterpenes, flavonoids, Aliso blanco, aliso colorado skin irritations, bone and arthritic activity tannins, phenolic compounds; δ- Cialdella 98 (SI) pains, cold, stomach and intestine Leaf: abortive effect; anti- amyrone (Olean-13-(18)-en-3-one), colics inflammatory apigenin-4’7-dimethylether (5-hidroxy- CAT, JUJ, SAL, TUC c’7-dimethyoxyflavone) BIGNONIACEAE Adenocalymma Part not specified: aphrodisiac, No biological test No data marginatum (Cham.) DC. digestive Isipó morotí COS, ERI, MIS Mroginski 334 (CTES) Amphilophium Leaf: antiseptic Aerial parts: antibacterial No data cynanchoides (DC.) L. G. BAI, CAT, CHA, COR, COS, ERI, activity Lohmann FOR, JUJ, LRI, MIS, SAL, SDE, KURTZIANA Sacha esponja SFE,SJU, SLU,TUC Pithecoctenium cynanchoides DC. Hunziker 15358 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Dolichandra cynanchoides Aerial parts: for headaches and Aerial parts: antioxidant Leaf. Cynanchoside, macfadienoside, Cham. migraines activity 5,7- bisdeoxycynanchoside: iridoids Sacha huasca, pata de gallo, Leaf: antidiarrheal, anti-emetic, (sub nom. M. cynanchoides) clarín, bignonia colorada, contraceptive, for humoral and clarín, teyú, trompeta de blood diseases Venus, mil hombres, falso BAI, CAT, CHA, COR, COS, ERI, mil hombres, sanalotodo FOR, JUJ, LRI, MIS, SAL, SDE, Macfadyenia cynanchoides SFE, TUC (Cham.) Morong Hunziker 15398 (CORD) Dolichandra unguis-cati Entire plant, infusion & decoction: Dried leaf: antitrypanosomal Dried aerial parts. β-amyrin : (L.) L.G. Lohmann for snakebite, for infections activity triterpene; pectolinarigenin-7-O-β-D- Uña de gato, garra de gato Aerial parts: against glucoside: flavone Macfadyena unguis-cati (L.) gastrointestinal, bloating, vaginal Dried vine. Chlorogenic acid: A. H. Gentry mycosis, anuria, urin with blood phenylpropanoid; corymboside: Ariza Espinar 1871 (CORD) Root: galactogene flavone Leaf, infusion: analgesic, diuretic, Dried root. Quinovic acid: triterpene febrifuge Fruit, infusion: to treat arthritis and rheumatism BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, MIS, SAL, SFE, TUC Fridericia truncata Sap: for dermatosis No biological test No data (Sprague) L.G. Lohmann CHA, FOR, JUJ, SAL, SDE, TUC Cabrera 21106 (CORD) Jacaranda micrantha Cham. Part not specified: antitussive, matu- No biological test Dried leaf. Cyclohexa-2-5-dien-1-ol,1- Caroba, caroba blanca rating, febrifuge, for puerperal baths hydroxy-4-oxo: ethyl acetate Deginani 1220 (CTES, SI) COS, MIS Fruit. Cyanogenic glycosides Jacaranda mimosifolia D. Root: sudorific, emetic, cathartic Dried leaf: cytotoxic activity Fresh flowers. -3-O-β-D- Don Bark, infusion: for fertility Dried twig: hypotensive activity rutinoside: flavonoid M14652; Jacarandá, Mazaré, palo regulation jacaranone: quinoid mármol, tarcol, tarco Dried leaf: for liver disorders, Dried fruit. Acetate ethyl-2-(1- Kurtz 16286 (CORD) antisyphilitic, for infections hydroxy-4-oxo-2-5-cyclohexadienyl): (compresses) benzenoid; apigenin, apigenin-7-O-β- Part not specified: abortifacient D-glucuronopyranoside: flavone 165 ERI, JUJ, SAL, TUC

166 Pyrostegia venusta (Ker Stem + leaf: tonic, for treating Leaf: antioxidant activity Root. Allantoin, β-sitosterol, Gawl.) Miers diarrhea and dysentery hesperidine, 3β-0-β-D- Tomo34(1-2):7-365.2009 Morrone 2143 (SI) COS, MIS glupyranosylsitosterol Leaf: flavonoids, phenolics Flower. β-sitosterol, n-hentriacontan, 7- 0-β-D-glycopyranosilacacetin, meso- inositol Tabebuia aurea (Silvia Bark: digestive, anti- Stem bark: uterine stimulant Dried leaf. Cynaroside, luteolin,6- Manso) Benth. et Hook. f. ex inflammatory; for skin eruptions; effect hydroxy, luteolin,6-hydroxy: 7-O- S. Moore decoction: febrifuge, anti-emetic (sub nom. T. caraiba) glucoside: flavone Lapacho amarillo, paratodo, Stem bark, infusion: abortifacient (sub nom. T. caraiba) quirai (sub nom. T. caraiba) Tabebuia caraiba (Mart.) COS, FOR, SAL Bureau Arbo 8877 (CTES) Tabebuia heptaphylla Wood: antirheumatic, diuretic, Bark + leaf: antimicrobial Bark + leaf. Furanonaphtoquinones (Vell.) Toledo abortive activity (sub nom. T. ipe) (sub nom. T. ipe) Lapacho, lapacho morado, Bark + leaf: diuretic, astringent, Dried bark: antibacterial Leaf: flavonoids lapacho negro, lapacho antiseptic activity crespo Dried bark, decoction: to treat Leaf: antioxidant activity Tecoma ipe Mart. ex K. urinary tract infections, against Schum. diarrhea, to treat injure of the skin Martínez 514 (CORD) Flowers: expectorant (sub nom. T. ipe). CHA, COS, ERI, FOR, MIS, SFE Tabebuia impetiginosa Dried bark, decoction: for urinary Aerial parts: antibacterial Dried bark. Ajugol,6-0-(4-hydroxy- (Mart. ex DC.) Standl. tract infections, diuretic; infusion: activity benzoyl): iridoid monoterpene; Lapacho laxative, Stem bark: antinociceptive, anisaldehyde: benzenoid; naphtho(2,3- Tabebuia avellanedae anti-hypoglycemic, hypotensive, antiedematogenic, antiviral, anti- b)-furan-4-9-dione,2-acetyl: quinoid Lorentz ex Griseb. stimulant, anti-emetic, trypanosomicidal, antifungal, Stem bark. Lapachol, α- and β- Bodenberger 12958 (CORD) abortifacient, antibacterial, and anti-tumor lapachone; cycloolivile, aryltetraline: Leaf: astringent, vulnerary, activity lignans; furanonaphtoquinones (sub KURTZIANA antiseptic, for psoriasis, anti- nom. T. avellanedae) haemorrhoidal; decoction: against Dried heartwood. 1-hydroxy cancer anthraquinone: quinoid; 2-methyl Flowers: antitussive, expectorant. anthraquinone: quinoid; lapachol CAT, JUJ, SAL, TUC

Tabebuia nodosa (Griseb.) Bark and flowers: to loose weight No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Griseb. CAT, CHA, COR, COS, FOR, Palo cruz, toroguatay, palo JUJ, LRI, SAL, SDE, SFE, TUC sinvergüenza, huiñaj Hunziker 17143 (CORD) Tecoma stans (L.) Juss. ex Entire plant: antipyretic, for Dried leaf + stem: Callus tissue, leaf. Actinidine: Kunth gastritis, cathartic, diuretic, hyperlipidemic activity; monoterpene alkaloid; α-amyrin: Guarán guarán, guarán analgesic, heart and skin problems, antidiabetic effect triterpene amarillo, fresnillo, fresno, gastrointestinal, urinary, Leaf: antifungal activity Dried seed. Arabinose: carbohydrate garrocha, garrocha amarilla, gynecological/obstetric and Leaf. 4-hydroxy benzoic acid: sauco amarillo, trompetilla, respiratory disorders benzenoid; caffeic acid: tronador Root: diuretic, hypoglycemic phenylpropanoid; anthranilic acid Rivera 96 (CORD) Bark, infusion & decoction: for :alkaloid-misc.; plantarenaloside: hypoglycemic iridoid monoterpene. Dried branches, infusion: Fungus infected leaf. Quercetin: antihypertensive flavonol Dried leaf + stem, decoction: hypoglycemic CAT, COS, ERI, JUJ, MIS, SAL, SDE, SFE, TUC BIXACEAE Bixa orellana L. Root: diuretic, vermifuge, anti- Dried root: hypotensive activity Leaf. Apigenin-7-bisulfate, hipoaletine, Urucú, bija, bixa, a nnatto, syphilitic Dried branch + leaf: antivenin cosmosiine; geraniol, geranyl formiate orellana, achiote, achote, bija, Bark: refrigerant, emmenagogue, effect farnesyl acetone; ; ishwarane urucum, otta, otto antitoxic, stomachic, antidote Dried leaf: anticonvulsant, Seed., β-bixin, β-carotene, Tolaba 2134 (CORD) Branch + leaf, decoction: for analgesic, antidiarrheal, cryptoxanthin, lutein, zeaxanthin, snakebite as a drink antioxidant, antimalarial, anti- methyl bixin, norbixin, orelline, 6- Leaf, infusion: for agitation, astrin- inflammatory, antifungal and geranylgeranyl 8'-methyl-6,8'- gent, diuretic, stomachic; for blood antibacterial activity; effect on diapocaroten-6,8'-dioate, 6- disorders, dysentery (amebiasis), for gastrointestinal motility; geranylgeranyl 6'-methyl (9'Z)-6,6'- leucorrhea and vaginitis aldolase inhibition; increases the diapocaroten-6,6'-dioate and 6- (trichomoniasis), tonic, calmative production of gastric mucus geranylgeranyl 6'-methyl-6,6'- Dried leaf + seed, decoction: for Dried fruit: antiviral and diapocaroten-6,6'-dioate, methyl (9Z)- diarrhea, diuretic antibacterial activity 8 -oxo-6,8 -diapocaroten-6-oate, Seed: to treat dizziness, antidiarrheal, Seed: hypoglycaemic activity methyl (9Z)-10 -oxo-6,10 - febrifuge, digestive, cardiotonic, diapocaroten-6-oate, methyl (9Z)-14 - laxative, emmenagogue, cicatrizant, oxo-6,14 -diapocaroten-6-oate: for sun-burns, bleeding, dysentery, carotenoids; oleic acid, linoleic acid, δ- 167 gonorrhea, constipation tocotrienol: lipids; ishwarane CHA, COR, FOR, SAL

168 BOMBACACEAE Ceiba chodatii (Hassl.) Spines: hepatic, to relieve the No biological test Leaf. Mucilages Tomo34(1-2):7-365.2009 Ravenna lumbago and kidneys pains Yuchán, barrigudo (sub nom. Ch. insignis) Chorisia insignis auct. non CAT, CHA, FOR, JUJ, LRI, SAL, Kunth SDE, TUC Martínez 279 (CORD) Ceiba speciosa (A. St.-Hil., Flowers + thorns: analgesic, No biological test Gum exudate. L-arabinose, L- A. Juss. & Cambess.) diuretic , D-mannose,; D-galactose, D- Ravenna Cortex sap: to treat hernia glucuronic acid; trace of D-xylose Palo borracho Thorns: analgesic, antiasthmatic, Leaf. Mucilages Chorisia speciosa A. St.-Hil., to treat alcoholism Seed coat. Rhamnose, galactose and A. Juss. & Cambess. CHA, COS, FOR, MIS, SFE uronic acid: saccharides Venturi 852 (SI) (sub nom. Chorisia speciosa)

BORAGINACEAE Amsinckia calycina (Moris) Leaf: cicatrizant No biological test Plant. Intermedine, lycopsamine, Chater BAI, CHU, LPA, MEN, NEU, echiumine: pyrrolizidine alkaloids Hosseus 104 (CORD) RNE, SCR, TDF

Cordia ecalyculata Vell. Dried entire plant: appetite Whole plant: antiviral activity Fresh + dried entire plant. Allantoin: Colita, gomita, porangaba, suppressant, diuretic Leaf: antibacterial activity alkaloid; allantoic acid; potassium chá do bugre, café do mato Leaf: cardiotonic, stimulant, to Branches + leaf: cytotoxic Leaf. (+)-spathulenol, β-sitosterol, Cordia salicifolia Cham. heal lesions of leishmaniasis activity against cancer cells; palmitic acid, myristic acid, stearic Tressens et al. 3082 (CTES) COS, MIS cardiotonic properties, acid, oleic acid, linoleic acid hypolipidemic effects (sub nom. Fruit. Caffeine, potassium, allantoin, C. salicifolia) allantoic acid (sub nom. C. salicifolia) Cryptantha albida (Kunth) Part not specified: stomachic No biological test No data I. M. Johnst. CAT, JUJ, LRI, MEN, SAL KURTZIANA Borrajilla, borrajilla del campo, borraja, borrajita del campo Kurtz 15429 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Ehretia cortesia Gottschling Medicinal No biological test No data Cortesia cuneifolia Cav. COR, LRI, MEN, SDE, SFE, SJU, Hunziker 13269 (SI) SLU Heliotropium amplexicaule Aerial parts: sudorific, diuretic, Plant: toxic effect general Plant. 1,2-dehydropyrrolizidine Vahl anti-gout, antitussive, antiseptic, alkaloid Heliotropo cimarrón , Helio- hypocholesteremic, disinfectant, tropo d el camp o, heliotropo for cold silvestre, borraja del campo BAI, CAT, CHA, COR, COS, Hunziker 298 (CORD) DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Heliotropium curassavicum Aerial parts: gout, rheumatism, Dried aerial parts: antiviral and Dried root. Retronecine: pyrrolizidine var. argentinum I. M. Johnst. neuralgias, arteriosclerotic genotoxic activity alkaloid Cola de gama, heliotropo, disorders, muscular algias, yerba meona, jaboncillo, pata phlebitis, varix de gallo. BAI, CAT, CHA, COR, COS, Ariza Espinar 3188 (CORD) DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC Heliotropium elongatum Aerial parts: hepatic No biological test No data Hoffm. ex Roem. & Schult. CHA, COR, COS, ERI, FOR, MIS, Borraja del campo SAL, SFE Barboza 385 (CORD) Heliotropium indicum L. Entire plant, infusion: for ulcers, Entire plant: hepatotoxic and Dried entire plant. Lupeol: triterpene Hunziker 5679 (CORD) externally for urticaria; antitumor activity Dried leaf. Acacic acid lactone: abortifacient; decoction: for herpes triterpene; β-amyrin, daucosterol: Leaf: emollient, for treating triterpene wounds externelly. Seed. Heliotridine-n-oxide, heliotrine: Dried aerial parts, decoction: pyrrolizidine alkaloids antidiarrheal, for bites and stings Flowers, infusion: abortifacient, emmenagogue CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Heliotropium procumbens Leaf: feverish child No biological test No data

Mill. CHA, FOR, JUJ, MIS, SAL, TUC 169 Barboza et al. 366 (CORD)

170 Heliotropium Aerial parts: diuretic No biological test No data veronicifolium Griseb. CAT, CHA, COR, FOR, JUJ, LRI, Tomo34(1-2):7-365.2009 Chiarini 243 (CORD) SAL, SDE, SFE, TUC Patagonula americana L. Bark: cicatrizant, anti-syphilitic No biological test Bark. Quinones Guayaibí blanco, guayaibí-rá, Leaf: vulnerary Part not specified. Cordiachrome G, saucillo, guayaibí-morotí CHA, COS, FOR, JUJ, MIS, SAL, H, peuchdiachrome H: sesquiterpenoids Martínez 176 (CORD) SFE Phacelia cumingii (Benth.) Part not specified: analgesic, No biological test No data A. Gray diuretic, sedative, aromatic Kiesling 9025 (SI) CAT, CHU, LRI, MEN, NEU, SAL, SCR, SJU Phacelia secunda J. F. Gmel. Leaf: hemostatic, cicatrizant, for No biological test No data var. secunda burns Yerba de la vída, té de la Part not specified: analgesic, anti- vida, oreja de ratón, yerba de inflammatory, diuretic, sedative San Blas CAT, CHU, COR, JUJ, LRI, Hieronymus 756 (CORD) MEN, NEU, RNE, SAL, SCR, SJU, TDF, TUC Tournefortia lilloi I. M. Part not specified: medicinal No biological test No data Johnst. JUJ, SAL, TUC Venturi 316 (SI) Tournefortia paniculata Part not specified: medicinal No biological test No data Cham. var. paniculata COS, MIS Hunziker et al. 15451 (CORD) Varronia curassavica Jacq. Leaf + leafy stem: vermifuge, Leaf + stem: antiedematogenic Aerial parts essential oil. α-pinene, Cordia curassavica (Jacq.) antispasmodic, digestive, antitoxic, and antinociceptive, anti- trans-caryophyllene, Roem. & Schult. to cure cough, anti-inflammatory, inflammatoriy and antiulcer alloaromadendrene (sub nom. C. Cordia verbenacea DC. bladder diseases activity verbenacea) KURTZIANA Cabrera 33892 (SI) (sub nom. C. curassavica) (sub nom. C. curassavica) Leaf + stem. Artemetin: flavonoid (sub Aerial parts: antirheumatic, anti- Leaf + stem: antimicrobial nom. C. curassavica) inflammatory, analgesic (sub nom. activity (sub nom. C. C. verbenacea) verbenacea) CAT, COS, FOR, JUJ, LRI, MIS, SAL, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina BRASSICACEAE Lepidium aletes J. F. Macbr. Root: hepatic, digestive No biological test No data Mastuerzo BAI, CHA, CHU, COR, COS, Cantero et al. s.n. (RIOC ERI, FOR, JUJ, LPA, MEN, MIS, 2041) NEU, RNE, SAL, SCR, SDE, SFE, SJU, SLU Lepidium argentinum Thell. Root: hepatic No biological test No data Hunziker 19664 (CORD) LRI Lepidium bonariense L. Root: hepatic Plant: antimicrobial activity Plant. p-methoxybenzylisothiocyanate Yerba de la pastora, bolsa de Leaf: digestive, for anemia and Seed. p-hydroxybenzyl glucosinolate, pastor, mastuercito, mastuer- tuberculosis sinigrin, glucotropaeolin, zo loco Part not specified: astringent, glucoaubrietin: glucosinolates; Hunziker 14510 (CORD) antidiarrheal, stomachic alkaloids BAI, CHA, CHU, COR, COS, DFE, ERI, JUJ, LPA, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC Lepidium didymum L. Entire plant: antimalarial, Dried entire plant: diuretic, Dried entire plant. Benzyl cyanide: Mastuerzo, quimpe antiscorbutic, expectorant, for antiviral, and antioxidant activity benzenoid; chrysoeriol, cynaroside: Coronopus didymus (L.) Sm. hernia and prolapse, menstrual Leaf, flower + fruit: flavones; chrysazin: quinoid Hunziker 12728 (CORD diseases, neonatal and paediatrics antibacterial activity Aerial parts essential oil. care, used in pregnancy and (sub nom. C. didymus) Benzylmercaptan, benceneacetonitrile, facilitate birth benzylbisufide, benzyltrisulfide and Aerial parts: antiscorbutic, hydrocarbons of high molecular weigh vulnerary, anti-inflammatory, Dried seed. Glucosinolate: sulfur antiseptic, to prevent the compound pyorrhoea, hemostatic, astringent, (sub nom. C. didymus) for humoral and blood diseases; infusion: used for intermittent fever, against cancer Flowers: for vaginal fungus Fruit juice, against cancer (sub nom. C. didymus) BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SCR, SDE, SFE, 171 SJU, SLU, TDF, TUC

Lepidium meyenii Walp. Tuber: to treat infertility in men Dried tuber: antifatigue Aerial parts. Benzylmercaptan, Papa macaia, macaia, maca, and women, frigidity, sexual activity; level benceneacetonitrile 172 chilque impotence and mental deficiency; increased; reduce prostate size; Dried tuber. Alanine: aminoacid; Tomo34(1-2):7-365.2009 Hunziker 20966 (CORD) anticarcinogenic effect, to regulate antiosteoporosis activity; campesterol β-sitosterol,: sterols changes in menstruation and the progesterone secretion Dried root. Lepidiline A, B: alkaloids; menopause, to alleviate insomnia inhibition; estrogenic effect benzyl-isothiocyanate, p-metoxybenzyl and the loss of hearing and vision, isothiocyanate: isothiocyanates to treat malnutrition, aid Hypocotyls-roots. Carbohydrates, convalescence, and restore proteins, lipids; essential amino acids, iron, physical and mental capacity calcium; linolenic, palmitic and oleic acids; CAT, JUJ, SAL, TUC sterols, alkaloids, vitamins, steroidal saponines, triterpenes, phenol compounds, flavonoids and/or coumarins, tannins, glycosides, secondary aliphatic amines and tertiary amines, prostaglandines, amides of polyunsaturated fatty acids Lepidium tandilense Boelcke Plant: antiscorbutic, tonic, diuretic No biological test No data Correa s.n. (SI 28561) BAI, RNE BUDDLEJACEAE Buddleja araucana Phil. Part not specified: vulnerary, No biological test No data Matico, panil balsamic, digestive, hepatic Kurtz 6090 (CORD) MEN, NEU, RNE Buddleja cordobensis Aerial plant: astringent, vulnerary, Aerial parts essential oil: Dried aerial parts. Catalpol: iridoid Griseb. for bronchitis; to treat anorexia and virucidal activity glucoside Palo blanco, salvialora, salvia lack of appetite Aerial part: strong inhibition de la hora, pulmonaria, salvia Leaf, decoction: for skin affections against taq DNA polymerase blanca, yerba del águila, (insects bite, gazes) sanalotodo Part not specified: emmenagogue Di Fulvio 664 (CORD) COR, LRI, SJU, SLU Buddleja globosa Hope Dried aerial parts, infusion: Leaf: cytotoxic and Dried leaf. Coumaric acid,para methyl Pañil, panguil, matica, digestive, hepatic; decoction: to treat antiplasmodial activity; β- ester: phenylpropanoid palquín, matico, pallín, ballín urinary and respiratory tract infections glucuronidase inhibition Fresh leaf. Echinacoside: Bernardello 569 (CORD) Dried leaf, infusion: urogenital, Bark: antifungal activity phenylpropanoid KURTZIANA antiseptic; to treat chronic dysentery, Root. Buddledin A and B: for stomach ulcers, hemostatic, sesquiterpenes; dehydrobuddledin A, antirheumatic, spasmolytic, zerumbone, buddledones A and B antidiarrheal, antibacterial, anti- inflammatory, anti-haemorrhoidal, for treating wounds externally CHU, NEU, RNE

BARBOZA, G.E.etal.MedicinalfloraofArgentina Buddleja mendozensis Leaf: uterine tonic Aerial parts. Radical Aerial parts. Iridoids Benth. CAT, COR, JUJ, LPA, LRI, MEN, scavenging effect Salvialora, salvia de la hora, SAL, SDE, SJU, SLU, TUC salvilora, salvia blanca Ariza Espinar 3412 (CORD) Buddleja stachyoides Cham. Leaf + flowers: emollient, No biological test Part not specified. Iridoids & Schltdl. astringent, antihemorrhoidal, (sub nom. B. brasiliensis) Barbasco, palo blanco, pelu- antitussive, sudorific, anticatarrhal dilla, san juan c’ora, cambará, Dried leaf, infusion: analgesic, for cambará chico, cambará del arthritis; emollient, sedative, to campo, palo blanco, salvia treat hemorrhoids, antiasthmatic, blanca, verbasco, Yerba de anticatarrhal San Juan, matico de la puna, Root: against snakebite venom cenicienta, basea china, hoja (sub nom. B. brasiliensis) trapo, yerba del cuerno BAI, CAT, CHA, COR, COS, ERI, Buddleja brasiliensis Jacq. ex FOR, JUJ, MIS, SAL, SFE, TUC Spreng. Subils et al. 3501 (CORD) Buddleja thyrsoides Lam. Leaf: antiasthmatic, anticatarrhal No biological test Flower + leaf + stem. Alkaloids var. thyrsoides BAI, COS, MIS Leaf. Alkaloids, flavonoids, coumarins, Barbasco anthocyanins, saponins, volatile oils Arechavaleta s.n. (CORD) Buddleja tubiflora Benth. Aerial parts: antitussive No biological test No data Cambará chico CHA, COR, COS, ERI, FOR, Ariza Espinar 2510 (CORD) SDE, SFE Buddleja tucumanensis Aerial parts: for infections Aerial parts essential oil: Aerial parts essential oil. α-thujene, β- Griseb. Dried twig, infusion: astringent, insecticide activity pinene, α-pinene, p-cymene, α -trans- Salvia, matico de la puna, stimulant bergamotene, β-caryophyllene, yerba de salvia, San Juan Leaf: antiasthmatic, for muscle pains sabinene, limonene, terpinen-4-ol Cocucci 655 (CORD) CAT, CHA, JUJ, SAL, SDE, TUC CABOMBACEAE Cabomba caroliniana A. Leaf: astringent No biological test Plant. Tannins Gray BAI, COR, COS, ERI, RNE, SFE

var. caroliniana 173 Arbo 8692 (CTES)

174 CACTACEAE Tomo34(1-2):7-365.2009 Austrocactus patagonicus Part not specified: medicinal No biological test No data (F.A.C. Weber) Hosseus LPA, MEN, NEU, RNE, SCR Tuna Villamil et al. 1182 (CORD) Brasiliopuntia brasiliensis Part not specified: emollient, No biological test Nodes. Mucilage, carbohydrate (Willd.) A. Berger febrifuge (sub nom. O. brasiliensis) Opuntia brasiliensis (Willd.) SAL Haw. Krapovickas 31530 (CTES) Cereus aethiops Haw. Part not specified: purgative, to No biological test No data Hachón, quisco, cardoncito remove spines, hemostic, for Subils s.n. (CORD) internal injures and feet edema, cephalalgic, for epilepsy BAI, CAT, COR, LPA, LRI, MEN, RNE, SAL, SFE, SJU, SLU, TUC Cleistocactus baumannii Fruits: hemostatic No biological test No data (Lem.) Lem. CAT, CHA, COR, COS, ERI, Penca, cogote de suri, cola de FOR, JUJ, LRI, SAL, SDE, SFE, gato, uvilinhe TUC Chiarini s.n. (CORD 1032) Harrisia bonplandii (Pfeiff.) Part not specified: hemostatic No biological test No data Britton & Rose CHA, COS, ERI, FOR, JUJ, SAL, Martínez 487 (CORD) SFE Harrisia p omanensis (F. A. Part not specified: febrifuge No biological test No data C. Weberex K. Schum.) CAT, COR, FOR, JUJ, LRI, SAL, Britton & Rose subsp. SDE, SFE, TUC pomanensis Ulua KURTZIANA Luti s.n. (CORD 425) Maihueniopsis darwinii var. Part not specified: medicinal No biological test No data hickenii (Britton & Rose) R. BAI, CHU, MEN, NEU, RNE, Kiesling SCR Chupa sangre Cocucci 2301 (CORD)

Monvillea cavendischii Fruits: hemostatic No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina (Monv.) Britton & Rose CHA, COS, ERI, FOR, JUJ, MIS, Martínez 32 (CORD) SAL, SFE Opuntia elata var. Fruit: against influenza, for Plant: cardiac inhibitory effect; No data cardiosperma (K. Schum.) diarrhea hypotensive and asphyxia on the R. Kiesling CHA, COS, ERI, FOR, MIS, SFE respiratory motility effect; Tuna de perro sustained augmentation of Tressens 6882 (SI) contractility in excised duodenum and augmentation of contractility in excised pregnant uterus (sub nom. O. elata) Opuntia ficus-indica (L.) Stem: antirheumatic, antitussive, Dried aerial parts: diuretic, Fresh stem. α-amyrin: triterpene Mill. for gastric ulcers, hepatic, anti-allergic, anti-inflammatory Seed oil. 5-dehydro Avenasterol: Chumbera, tuna, penca, respiratory and kidney disorders activity steroid; oleic acid: lipid nopal, chumbera, higuera Flowers: diuretic Stem: antidiabetic activity Fresh fruit. Betanin: betaxanthin chumbera. Fruit: astringent; infusion: to Dried leaf + dried seed: Plant. Neobetanin, piscidic acid, Opuntia paraguayensis K. cicatrize ulcers, antidiabetic, hypoglycemic activity piscidic acid methyl ester: phenolics. Schum. antiscorbutic Dried flowers: diuretic and Subils s.n. (CORD 3336) BAI, CAT, CHA, COR, COS, ERI, antioxidant activity FOR, JUJ, LPA, LRI, MEN, SAL, SDE, SFE, SJU, SLU, TUC Opuntia quimilo K. Schum. Stem: hepatic, anti-lithic No biological test No data Quimilo, quimil, quimilí CAT, CHA, COR, FOR, JUJ, LRI, Hunziker s.n. (CORD f. 426) SAL, SDE, SFE, TUC Opuntia salmiana Parm. Part not specified: astringent No biological test No data Lágrima d el tig re, u turungo vaginal huackachina CAT, COR, ERI, JUJ, SAL, SDE, Hunziker 17421 (CORD) SFE, SLU Opuntia sulphurea var. Fruits: antirheumatic, antitussive No biological test No data pampeana (Speg.) Backeb. BAI, COR, LPA, SDE, SFE Hunziker 17715 (CORD) Pereskia sacharosa Griseb. Part not specified: emollient No biological test No data Saravia Toledo 734 (CORD) CAT, CHA, FOR, JUJ, SAL Quiabentia verticillata Leaf: for infected purulent spots No biological test No data (Vaupel) Borg CHA, FOR, JUJ, SAL 175 Fortunato et al. 1406 (BAB)

176 Rhipsalis baccifera (J.S. Aerial parts: for snakebites No biological test No data Muell.) Stearn subsp. Stem + fruit: antidiabetic Tomo34(1-2):7-365.2009 baccifera CHA, COS, FOR, JUJ, MIS, SAL Morrone et al. 1883 (SI) Rhipsalis floccosa subsp. Entire plant: against skin diseases Fruit: free radical scavenging No data tucumanensis (F. A. C. Weber) JUJ, SAL, TUC effect (sub nom. R. floccosa) Barthlott & N. P. Taylor Kuntze 7329 (CORD) Rhipsalis lorentziana Plant: neonatal and paediatrics No biological test No data Griseb. care Huasca huasca, peinquillita JUJ, SAL, TUC Barboza 1102 (CORD) Rhipsalis lumbricoides Part not specified: cardiotonic, No biological test No data (Lem.) Lem. ex Salm-Dyck hypotensive Martínez 38 (CORD) BAI, CHA, COS, ERI, FOR, JUJ, MIS, SAL, TUC Stetsonia coryne (Salm- Fruit: hepatic, refrigerant No biological test Part not specified. Coryneine, Dyck) Britton & Rose CAT, CHA, COR, FOR, JUJ, LRI, mescaline: alkaloids Cardón, tuna SAL, SDE, SFE Hosseus 130 (CORD) Trichocereus arboricola Part not specified: medicinal No biological test No data Kimnach SAL Hilgert 1510 (SI) Tunilla soehrensii (Britton Seed: febrifuge, for general body No biological test Dried fruit. (+) Balanophonin: lignan & Rose) D.R. Hunt & Iliff pains (sub nom. O. soehrensii) Airampo, airampu, lampari- Dried fruit: hemostatic llo, tunilla Part not specified: febrifuge, Opuntia soehrensii Britton & against measles, ophtalmic

Rose (sub nom. O. soehrensii) KURTZIANA Las Peñas 338 (CORD) CAT, JUJ, SAL CALCEOLARIACEAE Calceolaria filicaulis Clos Medicinal No biological test No data var. filicaulis CHU, NEU, RNE Cohete Cocucci 2158 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Calceolaria pinifolia Cav. Medicinal Dried aerial parts: Dried aerial parts. 19- Yerba del ciervo CAT, MEN, SJU antimycobacterial activity malonyloxydehydroabietinol and 19- Kurtz 3436 (CORD) methylmalonyloxy- ent-isopimara- 8(9),15-diene, 4-Epi-dehydroabietinol: diterpenes; 3-epi-ursolic acid and 3-epi- oleanolic acid, ent-isopimara-9(11),15- diene-19-ol: triterpenes Calceolaria santolinoides Aerial parts: to stimulate No biological test No data Kraenzl. parturition, abortive Cialdella 418 (SI) CAT, COR, JUJ, SAL, SLU, TUC Calceolaria teucrioides Aerial parts: diuretic, purgative, No biological test No data Griseb. febrifuge, antiseptic, vulnerary Kurtz 6864 (CORD) CAT, COR, JUJ, LRI, SAL, TUC CALLITRICHACEAE Callitriche lechleri Part not specified: medicinal No biological test No data (Hegelm.) Fasset BAI, CHU, COS, ERI, NEU, RNE, Illin 113 (CORD) SCR, TDF Callitriche terrestris subsp. Part not specified: for wounds No biological test No data subsessilis (Fassett) and bruises Bacigalupo BAI, CHA, COR, COS, ERI, FOR, Martínez 461 (CORD) JUJ, MIS, SAL, SFE, TUC CALYCERACEAE Acicarpha tribuloides Juss. Root: for treating wounds Dried aerial parts: analgesic, Dried aerial parts. Astragalin: Rosetilla, cardo torito, toro- externally, abluent antispasmodic activity flavonol; loganin: secoiridoid rati, roseta Dried aerial parts, infusion: monoterpene Chiarini 179 (CORD) expectorant, in hepatic infections; decoction: to treat urinary tract infections. BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, RNE, SAL, SDE, SFE, SLU, TUC Calycera herbacea Cav. var. Part not specified: for bruises No biological test Dried aerial parts. Astragalin, rutin: herbacea MEN, NEU, TUC flavonol Reinbach s.n. (SI) Gamocarpha selliana Aerial parts: stomachic, hepatic No biological test No data Reiche CHU, NEU, RNE, SCR, TDF 177 Bernardello 650 (CORD)

Nastanthus caespitosus Part not specified: stomachic No biological test No data 178

(Phil.) Reiche LRI, MEN, RNE, SJU Tomo34(1-2):7-365.2009 Cocucci 2218 (CORD) CAMPANULACEAE Wahlenbergia linarioides Part not specified: carminative, No biological test No data (Lam.) A. DC. antispamodic Uño perquén BAI, COR, COS, ERI, FOR, JUJ, Ariza Espinar 439 (CORD) LPA, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC CAPPARACEAE Capparis atamisquea Kuntze Fruit and leaf: antirheumatic, Aerial parts: antioxidant Leaf. Flavonoids Atamisque, matagusanos, digestive, antacid, anthelmintic activity leña hedionda, matanegra BAI, CAT, CHA, COR, ERI, JUJ, Cantero et al. s.n. (RIOC 1955) LPA, LRI, MEN, NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC Capparis retusa Griseb. var. Bark: for skin eruptions No biological test Dried leaf. Kaempferol, quercetin: retusa Seed, juice: purgative flavonol Sacha poroto, cocol, poroto, CHA, COR, COS, ERI, FOR, JUJ, guaicurú, poroto del monte MIS, SAL, SDE, SFE, TUC Cocucci 1206 (CORD) Capparis salicifolia Griseb. Entire plant: purgative No biological test Plant. Glucocapparin and/or other Sacha sandía, sandía Root, decoction: anti-syphilitic glucosinolates hedionda, palo verde, sandía CHA, FOR, JUJ, SAL, SDE Dried leaf. Iso Rhamnetin: flavonol de cabra Dried seed. Glucocappasalin: sulfur Martínez 387 (CORD) compound Capparis speciosa Griseb. Dried bark: to cause embedded No biological test Dried leaf. Kaempferol, quercetin: Sacha limón, amarguillo, palo thorns to come out of skin flavonol verde, naranjo del monte, Leaf: antidysenteric bola verde CAT, CHA, COS, FOR, JUJ, SAL,

Cocucci 1305 (CORD) SDE, SFE, TUC KURTZIANA Capparis tweediana Eichler Leaf, decoction: antitussive, No biological test Dried leaf. Kaempferol, quercetin: Sacha membrillo, cayampa, sedative, antidysenteric, to cause flavonol mbuycuré-caá, hoja redonda, furuncles to come to a head Plant. Glucocapparin and/or other mata burro, meloncillo, BAI, CHA, CHU, COR, COS, glucosinolates comida de burro ERI, FOR, JUJ, LRI, MIS, SAL, Subils 2027 (CORD) SDE, SFE, SJU, TUC

Cleome hassleriana Chodat Entire plant: rubefacient, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Burkart 21197 (SI) digestive, antiscorbutic BAI, CHA, COR, COS, ERI, MIS, SAL, SFE, TUC Cleome parviflora Kunth Leaf: eye infection No biological test No data Zuloaga 2146 (SI) BAI, COS, ERI, MIS Cleome trachycarpa Part not specified: No biological test No data Klotzsch ex Eichler antihemorroidal Hunziker 972 (CORD) BAI, CHA, COS, DFE, ERI, FOR, MIS, SFE CARDIOPTERIDACEAE Citronella gongonha (Mart.) Leaf: diuretic No biological test Aerial parts. Kingisidic acid, 8-epi- R. A. Howard COS, FOR, MIS kingisidic acid Arbo 6860 (CTES) CARICACEAE Carica glandulosa Pav. ex Latex: anthelmintic No biological test No data A. DC. JUJ, SAL, TUC Higuera del monte Barboza 1095 (CORD) Carica papaya L. Leaf: digestive, antiparasitic Root: antibacterial activity Plant. (R)-2-(β-D- Mamón, papaya, lechosa, Leaf latex: antihemintic and for Leaf: hypoglycemic effect Glucopyranosyloxy)-2- ababa, papayero, mamón treatments of infections of bacterial Fruit latex: activity in phenylacetonitrile (prunasin) macho origin mammalian wound healing, Shoot. Kaempferol, quercetin Pedersen 5065 (LP) Flowers: antitussive, antiasthmatic digestive conditions, Leaf. 5,7-dimethoxycoumarin, Fruit + seed: antiparasitic immunomodulation, and protocatechuic acid, p-coumaric acid, CHA, COS, FOR, MIS, SAL, TUC neoplastic alterations; caffeic acid, chlorogenic acid, antiulcerogenic, antihelmintic, kaempferol, quercetin; carpaine, antitumoral, and debridement pseudocarpaine, dehydrocarpaine I and activity II: alkaloids; cyanogenic compounds Seeds: antiamoebic, giardicidal, Fruit latex. Papain, caricain, chymopapain immunostimulatory and anti- A and B, papaya peptidase A, glycyl- inflammatory actions endopeptidase; proteinase A and B; Latex: fungicidal and chitinase; lipases; glucosidases; flavonoids; bacteriolytic activity flavanol; alkaloids; benzyglucosinolate; carotene; lycopene Fruit pulp. Linalool Root. Saponins, alkaloids, tannins, 179 phenols, glycosides; cyanogenic compounds

180 Carica quercifolia (A. St.- Leaf: vermifuge, proteolytic Plant. (R)-2-( β-D- Hil.) Hieron. Latex: vermifuge, digestive No biological test Glucopyranosyloxy)-2- Tomo34(1-2):7-365.2009 Higuera del monte, higuera CAT, CHA, COS, FOR, JUJ, MIS, phenylacetonitrile (prunasin) salvaje, higuerita, sacha higo, SAL, SDE, SFE, TUC jacaratiá, higuerón Biganzoli 584 (SI) Jacaratia corumbensis Roots: stomachic, laxative, No biological test No data Kuntze diuretic, for skin eruptions Jacón Fresh root, juice: anti-emetic Fortunato 288 (BAB) CHA, FOR, JUJ, SAL, TUC Jacaratia spinosa (Aubl.) A. Plant: to control gastrointestinal Fruit: proteolytic activity Aerial parts. Amentoflavone, saponins DC. worms Fruit. Proteolytic enzymes Jacaratía, jacaratí-í Latex: cathartic, vermifuge, for Jacaratia dodecaphylla stomach disorders (Vell.) A. DC. Fruit: laxative Zuloaga 6805 (SI) COS, MIS CARYOPHYLLACEAE Arenaria lanuginosa (Michx.) Aerial parts: astringent No biological test No data Rohrb. var. lanuginosa CAT, COR, JUJ, LRI, SAL, SDE, Hunziker 6467 (CORD) SJU, TUC Cardionema kurtzii Subils Leaf: emmenagogue No biological test No data Hunziker 7839 (CORD) COR, MEN Cardionema ramosissima Leaf: emmenagogue No biological test No data (Weinm.) A. Nelson & J.F. BAI, CAT, CHU, COR, JUJ, LPA, Macbr. LRI, MEN, RNE, SAL, SCR, Yerba de la perdiz, dicha, SDE, SJU, SLU, TUC perlilla rosada Subils et al. 3218 (CORD) Drymaria glandulosa Bartl. Leaf: sedative cardiotonic No biological test No data Hunziker 9005 (CORD) CAT, COR, JUJ, LRI, SAL, SDE, KURTZIANA TUC Paronychia brasiliana DC. Leaf: diuretic, astringent No biological test No data var. brasiliana BAI, COR, COS, ERI, LPA, MIS, Paico, yerba tontita SAL, SFE Subils et al. 1559 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Paronychia chilensis DC. Branch: against skin diseases and No biological test No data subsp. chilensis wounds, urinary affections, against Burkart 4463 (SI) influenza, colds and cough, hepatic affections, to avoid vomiting BAI, CAT, CHU, COR, ERI, LPA, LRI, RNE, SCR, TUC Paronychia communis Leaf: stomachic, diuretic, No biological test No data Cambess. var. communis astringent Subils 2459 (CORD) CAT, CHA, COR, COS, ERI, JUJ, LRI, MIS, SAL, SJU, TUC Polycarpon suffruticosum Aerial parts: antidysenteric No biological test No data Griseb. BAI, CAT, CHA, COR, COS, ERI, Chiflón, ruda del campo FOR, JUJ, LRI, SAL, SDE, SFE, Cantero et al. s.n. (RIOC TUC 1214) Pycnophyllum convexum Medicinal No biological test No data Griseb. CAT, JUJ, SAL, TUC Hunziker 20896 (CORD) Spergula ramosa (Cambess.) Leaf and root: stomachic, No biological test No data D. Dietr. subsp. ramosa antispamodic, diuretic Arenaria roja BAI, CAT, CHA, CHU, COR, Hunziker 11410 (CORD) COS, ERI, JUJ, LRI, MEN, NEU, RNE, SAL, SCR, SFE, SJU, SLU, TUC Spergula villosa Pers. Plant: diuretic No biological test No data Spergularia villosa (Pers.) BAI, CAT, CHU, COR,, ERI, JUJ, Cambess. LRI, RNE, SCR, SFE, SJU, SLU Cabrera 33366 (SI) 181

CECROPIACEAE 182 Cecropia pachystachya Leaf: respiratory disorders, Leaf: diuretic, cardiotonic, Aerial part. Orientin, isoorientin, rutin, Trécul antitussive, expectorant, anti- sedative, broncodilatador, chlorogenic acid; pomolic acid Tomo34(1-2):7-365.2009 Ambay, ambaí, amba-í, asthmatic, tonic, cardiac, cardiotonic, hypotensive effects; Dried leaf. Luteolin-C-glycosides, amba-hú, ambaiba, ambay hypoglycaemic, diuretic, sedative, antioxidant, antimicrobial, isoorientin, catechin,(+): flavonoids; guazú, palo lija, palo de lija, against eye infections antimalarial and anti- protocatechuic acid: benzenoid; iso umbaúba, embaúva Trunk juice: against cutaneous inflammatory activity quercitrin: flavonol; β-sitosterine, stigmast- Cecropia adenopus Mart. ex bores 4-en-3-one, α- and β-amyrin, β-sitosterol; Miq. Twig juice: antidiarrheal alanine, glycine, serine, valine, isoleucine, Cecropia catharinensis CHA, COS, FOR, MIS, SFE asparagine, proline, aspartic acid, Cuatrec. phenylalanine, glutamic acid, arginine: Barboza 364 (CORD) aminoacids; glucose, fructose, galactose: sugars; ambain, ambainin: glucosides; cecropine, cecropinine, arachidonic acid; oxidases, mucilages, saponins (sub nom. C. adenopus and sub nom. C. pachystachya) Cortex. Cecropine: alkaloid; Root. β-sitosterol: steroid; tormentic acid: triterpenes Leaf. Vitexin, isovitexin, orientin and isoorientin: flavonoid glucosides (sub nom. C. catharinensis) Root + stem. 2α-acetoxy-3β,19α- dihydroxy-11α,12α-epoxy-ursan- 28,13β-olide, 3β-acetoxy-2α,19α- dihydroxy-11α,12α-epoxy-ursan- 28,13β-olide and 2-O-acetyl-euscaphic acid: triterpenes (sub nom. C. catharinensis)

CELASTRACEAE KURTZIANA Maytenus boaria Molina Leaf: cathartic, febrifuge, Leaf, flower + fruit: cytotoxic, Aerial parts. β-amyrin; lupeol; betulin Maitén, Maitén grande, horco antiseptic, antibiotic, for treating anti-tumoral and anti- lup-20(29)-ene-3β,30-diol, oleanolic molle, naranjita, yukirá wouds externally, detergent inflammatory activity acid: triterpenoids; betulonic acid; Hunziker 9943 (CORD) CHU, COR, MEN, NEU, RNE, epicatechol; 5’-O-methylgallocatechol; SCR, SJU, SLU, TDF 4-hydroxybenzaldehyde; 4,C4-dihydro- β-agarofuran sesquiterpenoids 1-8 Seed. β-agarofurans

Maytenus cuezzoi Legname Leaf: for infections, hernia and No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Lloque prolapse Novara 7102 (SI) JUJ, SAL Maytenus ilicifolia Mart. ex Entire plant, infusion: for fertility Dried leaf: barbiturate Dried leaf. α-amyrin, cangorosin A and Reissek regulation, antiasthmatic potentiation, antiulcer, B: terpenoids; maytefolins A, B, C, Pus pus, congorosa, conco- Aerial parts: vulnerary, antimicrobial, antitumoral, uvaol-3-caffeate, erythrodiol, betulin, rosa, quebrachillo, molle contraceptive, hypotensive, antioxidant, antinociceptive, betulin-3-caffeate, moradiol, morotí, cangorosa, cardiotonic, antidiarrheal , anti-inflammatory, and relaxant erythrodiol-3-caffeate, 20α- capororoca, molle espinoso, decongestant, odontalgic, for activity; toxic in rats during hydroxymaytenin, 22β- cancerosa, sombra de toro lumbago, kidney disorders, gastric pregnancy hydroxymaytenin, maytenin, celastrol, Lorentz 1226 (CORD) ulcers and gastritis, and articular Root bark: antioxidant activity; pristimerin: triterpenoids; afzelechin, pains myeloperoxidase inhibition; epiafzelechin, catechin, epicatechin, Flowers, decoction: anti- cytotoxic activity against V-79, gallocatechin and epigallocatechin, inflammatory KB, L1210, VJ300, KU 19-20 (epi)afzelechin-(epi)afzelechin, Leaf, antiasthmatic, antiseptic; and P 388 cells (epi)afzelechin-(epi)catechin, 4-O- infusion: emmenagogue, methyl-(epi)catechin, 4’-O- sialogogue , astringent, methyl(epi)catechin, (epi)afzelechin- antispasmodic, contraceptive, (epi)gallocatechin: tannins; quercetin, Root: diuretic, contraceptive, kaempferol; friedelin, friedelan-3-ol, α- emmenagogue tocopherol, simiarenol, lupeol, BAI, CHA, COS, ERI, FOR, MIS, lupenone, β-sitosterol, stigmasterol, SAL, SFE campesterol, ergosterol, brassicasterol, squalene, hexadecanoic acid, T1 and T2 –tocopherols; maytansine, maytanprine, maytanbutine: maytansinoids (alkaloids); cangorin F, G, H, I, J; phytol, vitamin E, dodecanoic acid, geranyl acetate; Fe, K, Mg, S, Na, Ca. Dried root bark. Cangorin A, B, C, D, E, F, G, H, I, J: sesquiterpenes; friedoolean-24-al-3-en-3-ol-2-on-29-oic acid (cangoronine), friedoolean-1-en- 29-ol-3-one (ilicifoline), maytenoic acid, D:B-friedoolean-5-en-3β,29-diol, D:A-fredoolean-29-ol-3-one, pristimerin, salasperimic acid,

isopristimerin, isotingenone, 6- 183 oxotingenol: triterpenes Root. milicifolines A-D: triterpenoids

Maytenus vitis-idaea Griseb. Leaf: astringent, stomachic, No biological test Fresh + dry leaf. Delphinidin: 184

Carne gorda, sal de indio, ophtalmic, cicatrizant, for insects, condensed tannin Tomo34(1-2):7-365.2009 colkiyuyo, Ivá-yeguí, spiders and snakes bites; cosquiyuyo, tala salado, decoction: to treat urinary and yerba del tapir, chaplán respiratory tract infections Cantero et al. s.n. (RIOC BAI, CAT, CHA, COR, COS, ERI, 1465) FOR, JUJ, LPA, RNE, SAL, SDE, SFE, SJU, SLU, TUC Moya scutioides Griseb. Aerial parts: antidiarrheal, for No biological test Dried root bark. β-amyrin: triterpene; Abriboca stomachache netzahualcoyene: triterpene; 15-α- Maytenus scutioides (Griseb.) (sub nom. M. scutioides) hydroxy pristimerin: triterpene; triscutin Lourteig & O’Donell JUJ, SAL B: triterpene Lorentz & Hieronymus 608 (sub nom. M. scutioides) (CORD) Moya spinosa Griseb. Leaf: antidiarrheal, stomachic No biological test No data Abriboca (sub nom. Maytenus spinosa) Maytenus spinosa (Griseb.) BAI, CHA, COR, COS, ERI, JUJ, Lourteig & O' Donell LPA, LRI, SAL, SDE, SFE, SLU, Hunziker 22625 (CORD) TUC CELTIDACEAE Celtis chichape (Wedd.) Leaf: antidiarrheal, antidysenteric, No biological test No data Miq. digestive, for stomachache Tala pispita CAT, CHA, COR, COS, ERI, Hunziker 22939 (CORD) FOR, JUJ, LRI, SAL, SDE, SFE, TUC Celtis iguanaea (Jacq.) Sarg. Aerial parts: for hernia and prolapse Fruit: free radical scavenging Leaf. Glycoflavones Talita, tala gateadora, horco tala Leaf: astringent, antidiarrheal, effect Fruit. Proteins Celtis pubescens (Kunth) menstrual disease Spreng. BAI, CAT, COS, ERI, FOR, JUJ,

Cocucci 3205 (CORD) MIS, SAL, SFE, TUC KURTZIANA Celtis pallida Torr. var. pallida Bark: aperitive No biological test Leaf. Glycoflavones Talilla, churqui tala, tala de Leaf: disinfectant, antidiarrheal los alambrados, tala chiquito, CAT, CHA, COR, ERI, FOR, tala churqui, tala, tala LPA, LRI, SDE, SFE, SJU, SLU, mogote, tala pispo TUC Hunziker 17654 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Celtis tala Gillies ex Planch. Bark: aperitive Leaf: antibacterial activity Leaf. Flavonoids Tala, tala blanco, tala Leaf: disinfectant, astringent, amarillo, yoasí digestive, antidiarrheal; decoction: Hunziker 18125 (CORD) to treat urinary and respiratory tract infections BAI, CAT, CHA, COR, ERI, FOR, JUJ, LPA, LRI, MEN, SAL, SDE, SJU, SLU, TUC CHENOPODIACEAE Atriplex cordobensis Gand. Leaf: disinfectant No biological test No data & Stuck. subsp. cordobensis CAT, COR, LRI, SAL, SDE, SFE, Cachiyuyo SJU, SLU, TUC Hunziker 7646 (CORD) Atriplex crenatifolia Chodat Part not specified: astringent, No biological test No data & Wilczek digestive, to relieve bruises Múlgura 1185 (CORD) COR, MEN, NEU, SJU, SLU Atriplex lampa (Moq.) D. Part not specified: astringent, No biological test No data Dietr. digestive, to relieve bruises Lampa o zampa BAI, CAT, CHU, COR, LPA, LRI, Cocucci 3547 (CORD) MEN, NEU, RNE, SAL, SCR, SJU, SLU, TUC Atriplex montevidense Aerial parts: emollient, to relieve No biological test Spreng. bruises No data Cachiyuyo BAI, CHA, CHU, COR, ERI, Schinini 16030 (SI) LPA, MEN, RNE, SDE, SFE Atriplex undulata (Moq.) D. Aerial parts: astringent, to relieve No biological test No data Dietr. bruises Cachiyuyo, zampa crespa, BAI, CHU, COR, LPA, MEN, zampa blanca RNE, SFE Hosseus 394 (CORD) 185

Chenopodium ambrosioides Leaf + fruits: emmenagogue, Aerial parts essential oil: Aerial parts. (-)(1R’,4S’)-1,4- 186

L. digestive, diuretic, antispamodic, antiparasitic, antimalarial, Dihydroxy-p-menth-2-ene, (-)(1R’, 2S’, Tomo34(1-2):7-365.2009 Paico, paico macho, té de los hypotensive, diaphoretic, antileishmanial, cardiotonic, 3S’, 4S’)-1,2,3,4-Tetrahydroxy-p- jesuitas, pichim tirao, paico anthelmintic hypotensive, and spasmogenic menthane, chenopanone hembra, yerba de Santa María Aerial parts, infusion: antitussive, activity; fumigant and repellent Aerial parts essential oil. Aritasone, Caro & Cocucci 3404 antiarthritic, antipyretic, activity against head lice limonene; cis-ascaridol, α-terpinene, (CORD) hemostatic, for stomach-ache, Aerial parts: carcinogenic, camphor, trans-ascaridol, p–cymene, anthelmintic, emmenagogue, for giardicidal, anti-ulcerous, pinocarvone, α- and β-pinene, geraniol, asthma and tumors, appetitive; antimalarial, antileishmanial, α- and γ-terpineol, thymol, β- decoction: febrifuge and antibacterial activity; cyto- caryophyllene, γ-gurjunene, myrcene, Leaf, decoction: for intestinal and genotoxic effect phellandrene, safrol, n-docosane, n- parasites Leaf: antimicrobial, analgesic hentriacontane, n-heptacosane, n- BAI, CHA, COR, COS, DFE, ERI, and anti-inflammatory activity octacosane, p-cymol, spinasterol, FOR, JUJ, LPA, LRI, MEN, MIS, Leaf + flower: antispasmodic terpinyl-acetate, terpinyl-salicylate, RNE, SAL, SDE, SFE, SJU, SLU, activity triacontyl-alcohol TUC Entire plant. Saponins, trimethylamine, citric acid, salicylic acid, tartaric acid, succinic acid, butyric-acid, ferulic-acid, malic-acid, methylsalicylate, urease, vanillic-acid Fruit. Quercetin, kaempferol rhamnoside, anethole, santonin Root. Heterosides, betain Chenopodium chilense Dried aerial parts, infusion: for Dried aerial parts: spasmolytic Essential oil. Ascaridol Schrad. stomach-ache, appetitive activity Paico Leaf: antispamodic, diuretic, Hunziker 6497 (CORD) anthelmintic BAI, CAT, COR, JUJ, LPA, LRI, MEN, NEU, RNE, SJU, SLU Chenopodium haumanii Part not specified: digestive, No biological test No data Ulbr. sudorific, carminative, KURTZIANA Paico emmenagogue Lorentz 887 (CORD) COS, ERI Chenopodium hircinum Leaf: digestive, to relieve bruises No biological test Dried leaf. Quercetin-3- Schrad. subsp. hircinum BAI, CAT, CHA, COR, COS, rhamnoglucoside: flavonol Quinoa blanca, quinoa DFE, ERI, FOR, JUJ, LPA, LRI, criolla, ajara, yuyo blanco MEN, MIS, NEU, RNE, SDE, Novara et al. 8653 (CORD) SFE, SJU, SLU, TUC

Chenopodium mandonii (S. Aerial parts: stomach-ache, Dried aerial parts: antifungal Dried aerial parts. Pinostrobin: BARBOZA, G.E.etal.MedicinalfloraofArgentina Watson) Aellen rubefacient, nervine, for allergy; and antioxidant activity flavanone; daucosterol: sterol; geranyl Arca yuyo, yerba larca infusion: to treat parasites, for (sub nom. Ch. graveolens) acetate: monoterpene; 8-hydroxy Chenopodium graveolens var. gastro-intestinal ailments, sedative; elemol: sesquiterpene; flavonoids bangii (Murr) Aellen decoction: antidiarrheal (sub nom. Ch. graveolens) Hunziker 20099 (CORD) (sub nom. Ch. graveolens) CAT, JUJ, LRI, SAL, SJU, TUC Chenopodium multifidum Leaf: digestive, antispamodic, Aerial parts: antibacterial Aerial parts essential oil. Cis- L. diuretic, hypotensive, diaphoretic, activity; cyto- and genotoxic endoperoxide, trans-endoperoxide, Paico, paico hembra emmenagogue, anthelmintic effect hydroxyketones, p-cymene, 7-acetoxy- Cantero et al. s.n. (RIOC 281) BAI, CHA, CHU, COR, ERI, JUJ, p-menthane, p- menth-5-en-cis-1,2,4- LPA, MEN, RNE, SFE, SJU triol, p-menth-5-trans-1,2,4-triol, p- menth-5-en-cis-1,3,4-triol, ascaridole, limonene, carveol; flavonoids Chenopodium quinoa Willd. Part not specified: sudorific, Dried seed: antiyeast and Leaf. Kaempferol: flavonol; oleanolic acid, var. quinoa stimulant, anticatarrhal antioxidant activity; adjuvants quinoasaponin 7: triterpenes; camphene, β- Quinoa, quinoa negra, ajara Dried seed, infusion: for action; hypocholesterolemic pinene, p-Mentha-1(7),8-diene, α- Krapovickas 44412 (CTES) dislocations effect terpinene, p-cymene, trans-p-Menth-2-en- COR l-ol, γ-terpinene, camphor, pinocarvone, terpin-l-ol, trans-carveol, cis-ascaridole, cis-isoascaridole, α-terpinyl acetate, E- caryophyllene; nitrates, vitamin E, vitamin C, Na, carotenoids, proteins Dried seed. Androseptoside A; 28-O-β- glucopyranosyl-(1→3)-α-arabino pyranoside, 3-O-β-glucopyranosyl-(1→3)- β-galacto pyranoside, 28-O- β- glucopyranosyl-(1→3) esters of phytolaccagenic acid 3-O-α-arabino pyranoside, glycosides of oleonolic acid, 3- O-[(β-D20-xylopyranosyl)(1→3)-β-D- glucorono pyranosyl-6-OMe ester]- oleanoic acid, 3-O-β-D-glucopyranosyl- (1→3)-α-L-arabinopyranosyl phytolaccagenic acid, phyto laccagenic acid, hederagenin, monodesmosidic and bidesmosidic triterpene saponins of oleanolic acid, serjanic acid, 3β-hydroxy- 187 23-oxo-olean-12-en-28-oic acid, 3β- hydroxy-27-oxo-olean-12-en-28-oic acid,

Chenopodium quinoa Willd. and 3β, 23α, 30β-trihydroxy-olean-12-en- 188

var. quinoa 28-oic acid: saponins; calcium, Tomo34(1-2):7-365.2009 (continuation) phosphorus, iron, sodium magnesium, zinc, potassium, copper, mercury, cadmium; isoleucine, threonine, glycine, thiamine, folic acid, lysine, histidine, , methionine + cystine, riboflavin, β- carotene, biotin, vitamin A, vitamin B2, vitamin B6, vitamin C, vitamin E, pantothenic acid, γ-tocopherol, α- tocopherol; oleic acid, linoleic acid, palmitic acid, squalene; free fatty acids, conjugated diene hydroperoxides, hexanal; triglycerides, 1,2-diglycerides, monoglycerides, waxes; phosphatic acid, phosphatyl serine, phosphatidyl ethanolamine, phosphatidyl inositol, lysophosphatidyl ethanolamine, phosphatidyl choline, lysophosphatidyl choline, monogalactosyl diglyceride, digalactosyl diglyceride lysophosphatidyl ethanolamine, 7-stigmasterol, cholesterol, 5-campesterol, 5, 22-stigmasterol, 7- campesterol, 5, 24 (28)-avenasterol, β- sitosterol; proteic tryptophan, free tryptophan; starch, crude fibre, pentosans, dietary fibre; phytic acid; kaempferol 3-O- [β-D-apiofuranosyl(1″ ′-2″)]-β-D- galactopyranoside, kaempferol 3-O-[α-L- rhamnopyranosyl(1″ ″-2″)]-β-D- galactopyranoside, kaempferol 3-O-[β-D- apiofuranosyl(1″ ′-2″)-α-L- rhamnopyranosyl(1″ ″-6″)]-β-D- galactopyranoside, kaempferol 3-O-(2,6- di-α-L-rhamnopyranosyl)-β-D- KURTZIANA galactopyranoside, quercetin 3-O-[β-D- apiofuranosyl (1″ ′-2″)-α-L- rhamnopyranosyl(1″ ″-6″)]-β-D- galactopyranoside, quercetin 3-O-(2,6-di- α-L-rhamnopyranosyl)-β-D- galactopyranoside: flavonol glycosides; trypsin inhibitor units

Chenopodium retusum Leaf + fruits: digestive, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina (Moq.) Moq. anthelmintic, antispamodic, Burkart 23321 (CORD) diuretic, hypotensive, diaphoretic, emmenagogue, BAI, COS, ERI, LPA Suaeda divaricata Moq. Entire plant: alexipharmic No biological test No data Vidriera, jume blanco, jume, BAI, CAT, CHU, COR, FOR, JUJ, fume LPA, LRI, MEN, NEU, RNE, Hunziker 13488 (CORD) SAL, SDE, SFE, SJU, SLU, TUC CLUSIACEAE Rheedia brasiliensis (Mart.) Bark: medicinal Leaf: antioxidant activity Leaf. Epiclusianone, fukugetin Planch.& Triana Seed: to cure mange Pacuri Part not specified: for urinary Burkart 15339 (SI) tract diseases, arthritis and to relieve pain CHA, COS, FOR, MIS COMBRETACEAE Terminalia australis Cambess. Bark: astringent Dried aerial parts: antifungal Root bark. Alkaloids Amarillo del río, palo Leaf and stem: bactericidal activity Leaf. , flavonoids, glycosides amarillo, tanimbú activity Correa 5382 (BAB) BAI, COS, ERI, MIS Terminalia triflora (Griseb.) Part not specified: antiseptic Dried leaf: anti-HIV, Leaf. Gallicin: sesquiterpene; Lillo agent antinociceptive, and antifungal quercitrin: flavonol; ellagic acid: Amarillo del río, guayaibí CAT, CHA, COS, FOR, JUJ, MIS, activity , 2-O-galloylpunicalin: amarillo, lanza, lanza SAL, SFE, TUC amarilla, palo amarillo Hunziker 10012 (CORD) CONVOLVULACEAE Root: laxative Dried fruit + leaf + stem: Aerial parts. Hygrine, cuscohygrine, Convolvulus hermanniae L’ Leaf: vulnerary, anti-asthmatic antibacterial activity propylhygrine, phygrine, N- Hér. BAI, CAT, CHA, COR, COS, ERI, methylpyrrolidinylhygrine, N- Campanilla JUJ, LRI, MEN, MIS, NEU, RNE, methylpyrrolidinylcuscohygrine: Cocucci 2910 (CORD) SAL, SFE, SLU, TUC pyrrolidine alkaloids; nicotine: nicotinoid; tropinone, tropine, pseudotropine, 6β- hydroxytropan-3-one: tropane alkaloids;

acylated 3α, 6β-/3α,7β-dihydroxytropanes: 189 3α-acyloxytropane alkaloids; phenylpropanoids esters: 3β- acyloxytropane alkaloid

Convolvulus laciniatus Root: laxative No biological test No data 190 Desr. var. laciniatus Aerial parts: anti-asthmatic Campanilla BAI, CAT, COR, COS, ERI, JUJ, Tomo34(1-2):7-365.2009 Barboza 316 (CORD) LPA, RNE, SAL, SFE, SLU, SJU, TUC Dichondra microcalyx Aerial parts: vulnerary, digestive No biological test No data (Hallier f.) Fabris Leaf: emmenagogue Oreja de ratón, oreja de gato, Part not specified: cicatrizant, orejita astringent Dichondra sericea var. micro- BAI, CAT, CHA, COR, COS, calyx (Hallier f.) H. T. Buck DFE, FOR, JUJ, MIS, RNE, SAL, Hunziker 18232 (CORD) SDE, SJU, TUC Dichondra sericea var. Aerial parts: vulnerary, astringent, No biological test No data holoserica (O' Donell) Fabris antiseptic, digestive, anthelmintic, Oreja de gato cicatrizant Hunziker 15325 (CORD) BAI, CAT, CHU, COR, ERI, LPA, LRI, MEN, RNE, SDE, SLU Ipomoea cairica (L.) Sweet Root: diuretic, laxative Aerial parts: cytotoxic activity Aerial parts. Trachelogenin, (-)- Campanilla, bejuco, Leaf: vulnerary arctigenin: lignans; (+)-(8R,8'S)- mechoacán Flowers: pectoral thujaplicatin methyl ether, arctigenin, Chiarini 336 (CORD) BAI, CAT, CHA, COR, COS, DFE, , trans-2,3- ERI, FOR, JUJ, LPA, LRI, MIS, dibenzylbutyrolactone, vanillic acid, p- SAL, SDE, SFE, SJU, SLU, TUC hydroxybenzoic acid, methoxybenzoic acid, methylparaben, stearic acid, palmitic acid, olenic acid, friedelinol, β- sitosterol, stigmasterol Ipomoea carnea subsp. Stem: for bites, injures, and burns, Aerial parts: hypothermic Dried entire plant. Ipomose: fistulosa (Mart. ex Choisy) drastic activity carbohydrate D. F. Austin Dried leaf, infusion: to cause Shoots: antifungal activity Dried aerial parts. Calystegine B-1, Mandiyú-ra hallucinations; for swollen Leaf: tachycardia activity, β- calystegine B-2, calystegine C-1: Negritto et al. 504 (CORD) testicles. galactosidase inhibition tropane alkaloids; swainsonine: KURTZIANA COS, ERI Fresh leaf + stem: smooth indolizidine alkaloid muscle relaxant activity Dried . Petunidin-3-β- galactoside: flavonoid Latex. Carnein: serine protease Ipomoea descolei O´Donell Part not specified: aphrodisiac No biological test Dried root. Flavonoids present Chiarini 525 (CORD) COS, MIS

Ipomoea dumetorum Willd. Sap: dermatosis No biological test Seed. Ergine, ergometrine : lysergic BARBOZA, G.E.etal.MedicinalfloraofArgentina ex Roem. & Schult. CAT, JUJ, SAL, TUC acid amides Barboza et al. 603 (CORD) Ipomoea grandifolia Part not specified: laxative No biological test No data (Dammer) O´Donell BAI, CHA, COS, ERI, FOR, MIS, Campanilla, bejuco SAL, SFE, TUC Barboza et al. 450 (CORD) Ipomoea hieronymi (Kuntze) Root and leaf: laxative, drastic No biological test No data O’Donell var. hieronymi CAT, COR, JUJ, LRI, SAL, SLU, Mecho TUC Chiarini 270 (CORD) Ipomoea indica (Burm. f.) Entire plant, decoction: for No biological test Whole plant. Ipolearoside, ipolearic Merr. carbuncles and injures acid: glycosidic acids Campanilla Root + leaf: purgative, febrifuge, Aerial parts. Hygrine, cuscohygrine, Chiarini 384 (CORD) vulnerary N-methylpyrrolidinylhygrine, N- BAI, CAT, CHA, COR, COS, ERI, methylpyrrolidinylcuscohygrine: FOR, MIS, TUC pyrrolidine alkaloids; nicotine: nicotinoid; tropane alkaloids; aliphatic esters: 3α-acyloxytropane alkaloid Ipomoea nil (L.) Roth Leaf: alexipharmic, vulnerary Dried entire plant: antitumor Plant. Hygrine, 2,6-dehydrohygrine: Campanilla Seed, decoction: expectorant; activity pyrrolidine alkaloids; nicotine; tropane Chiarini 110 (CORD) infusion: purgative, to induce Seed: antifungal, nematocidal alkaloids; harman, nor harman: β- abortion and antiviral activity carbolines CAT, CHA, COR, FOR, JUJ, LRI, Stem, fruit + seed. N1, N10- MIS, SAL, SDE, SFE, SLU, SJU, ditigloylspermidine TUC Flowers. Cernuoside; chlorogenic acid: phenylpropanoid; different anthocyanins according to the flower colour (pelargonidin-, peonidin-, cyanidin glycosides); chalcononaringenin: flavanone Dried seed. Hevein homolog PN-AMP- 1 protein; β-ecdysone: sterol; “pharbitic acid”, ipurolic acid, ipolearic acid: glycosidic acids Cotyledons. Pinor-esinol 4-0-β-D-

glucoside: furfuran-type lignan; 191 sisymbrifolin: neolignan; gibberellin A26, A27, gibberellin glucosides

192

Ipomoea nitida Griseb. Part not specified: drastic No biological test No data Tomo34(1-2):7-365.2009 Batata purgante, batatilla, COS, ERI, MIS caá-parí Chiarini 520 (CORD) Ipomoea platensis Ker Root: drastic, purgative No biological test No data Gawl. BAI, CHA, COS, ERI, FOR, SAL, Tressens et al. 3744 (CTES) SDE, SFE, TUC Ipomoea purpurea (L.) Roth Root: laxative Seed: mutagenic activity Plant. Hygrine, cuscohygrine: Campanitas, suspiros, Leaf: alexipharmic, vulnerary, pyrrolidine alkaloids; tropane alkaloids campanilla, carregüela, antimicrobial Fresh leaf + stem. Marubajalapins I- campanilla azul. BAI, CAT, CHA, COR, COS, XI: misc lactone; operculinic acid, Chiarini 111 (CORD) DFE, ERI, FOR, JUJ, LPA, LRI, jalapinolic acid; N-trans- MEN, MIS, SAL, SDE, SFE, SLU, feruloyltyramine and its cis isomer; SJU, TUC chlorogenic acid, 3,4- and 3,5- dicaffeoylquinic acids Fresh petals. Mono-caffeyl cyanidin-3- sophoroside-5-glucoside: flavonoid Corollas. Triglucosyl-caffeoyl cyanidin-3-sophoroside: flavonoid Dried seed. Agroclavine: indole alkaloid; castasterone, 28- norcastasterone: steroids; eriodictyol-7- O-β-D-xylopyranosyl-(1→4)-β-D- arabinopyranoside: flavanone; lupeol: triterpene; ipopurpuroside; ricinoleic acid Immature seed. Gibberellin A-17: diterpene CORIARIACEAE Coriaria ruscifolia L. Part not specified: dermatologic Stem: pheromone Dried aerial parts. Coriamyrtin: KURTZIANA Deu, güisque, beu, huique, CHU, NEU, RNE Leaf + stem: cytotoxic activity sesquiterpene huiquehuiqui Flower + leaf + twig: Fruit. Corianin: sesquiterpene Fortunato 5261 (BAB) pheromone Fruit: antibacterial activity

CUCURBITACEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina Cayaponia bonariensis Plant: for snakebite Root: antimitotic activity Part not specified. Alkaloids and bitter (Mill.) Mart. Crov. Leaf: antitussive principles Sandía purgativa, papa Root, fruit + seed: purgative imperial, tayuyá, tayurá BAI, COR, DFE, ERI, FOR, MIS, Subils 3326 (CORD) SFE Cayaponia citrullifolia Root, infusion and decoction: for No biological test No data (Griseb.) Cogn. ex Griseb. fertility regulation, diaphoretic Ariza Espinar 755 (CORD) Part not specified: contraceptive CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, SAL, SDE, SFE, TUC Cayaponia podantha Cogn. Root: purgant Leaf: anti-inflammatory, No data Barboza 1570 (CORD) BAR, CHA, COR, COS, ERI, antiprotozoal, and antimicrobial FOR, JUJ, LRI, SAL, SFE activity Cucurbita maxima subsp. Fruit, vapor: expectorant; to Dried aerial parts: diuretic Leaf. Gentisic acid: benzenoid; andreana (Naudin) Filov alleviate chilblains activity gibberellin a-12,12-α-hydroxy: Zapallo del diablo, chancar, Seed, infusion and decoction: Flowers: toxic effect; diterpene zapallito amargo anthelmintic, purgative, vermifuge; anticlastogenic activity Flower essential oil. 1-4-dimethoxy Hunziker 11563 (CORD) to treat urinary tract infections, Dried leaf: antibacterial activity Benzene: benzenoid toxic Seed: cardiac depressant; and Dried fruit pulp. β-carotene: BAI, COR, ERI, LRI, MEN, SDE, anthelmintic activity carotenoid SLU Seed. Alanine, meta-carboxy-phenyl, arginine, lysine: aminoacids; β-amyrin: triterpene; trans-trans abietic acid: diterpene Cucurbitella asperata (Gi- Leaf: purgative, drastic No biological test No data llies ex Hook. & Arn.) Walp. BAI, CAT, CHA, COR, COS, ERI, Sandía del campo FOR, JUJ, LPA, LRI, MEN, SAL, Ariza Espinar 2215 (CORD) SDE, SFE, SJU, SLU, TUC Cyclanthera pedata (L.) Part not specified: anti- Fruit: antioxidant activity Leaf. 6-C-fucopyranosyl-(3-malonyl)- Schrad. inflammatory, hypoglycaemic and and 6-C-fucopyranosyl-(4- Achojcha hypocholesterolaemic properties malonyl)-chrysin: flavonoids Kiesling 1641 (SI) Dried fruit, infusion: Fruit. chrysin 7-O-â-D- hypoglycemic glucopyranosyl-6-Cfucopyranoside, Seed, infusion: for high blood chrysin-6-C-fucopyranoside, apigenin- pressure 6-C-fucopyranoside, chrysin 7-O-â-D-

JUJ, SAL glucopyranosyl-( 193 1f4)-R-L-rhamnopyranoside: flavone glycosides

194

Momordica charantia L. Root + fruit: abortifacient, Plant: hypoglycaemic and weak Root. Kuguacins A-E, 3β, 7β,25- Tomo34(1-2):7-365.2009 Balsamina, momordica, aphrodisiac anti-HIV-1 activity trihydrocycucurbita-5,(23E)-diene-19-al, tomacó Leaf + fruit: anthelmintic, Root: anti-HIV activity 3β, 25-dihydroxy-5β, 19-epoxycucurbita-6, Schinini 31811 (CTES) purgative, and for the treatment of Fruit + seed: antidiabetic agent (23E)-diene, momordicine I gastrointestinal disorders Immature fruit: antitumor Stem. Cucurbita-5,23(E)-diene- Fruits: anti-haemorrhoidal, agent 3β,7β,25-triol, 3β-acetoxy-7β- febrifuge, purgative Juice fruit: Lipid lowering effects methoxycucurbita-5,23(E)-dien-25-ol, Juice fruit: to treat diabetes and its in HIV-1-protease inhibitor-treated cucurbita-5(10),6,23(E)-triene-3β,25- complications human hepatoma cells; potent diol, and cucurbita-5,24-diene-3,7,23- Seed: for the treatment of inhibitor of apoB secretion and trione, (23E)-25-methoxycucurbit-23- bilousness and jaundice TAG synthesis and secretion in ene-3β,7β-diol, (23E)-cucurbita- BAI, COR, JUJ, LRI, SAL human hepatoma cells (HepG2); 5,23,25-triene-3β,7β-diol, (23E)-25- plasma apolipoprotein B-100 hydroxycucurbita-5,23-diene-3,7-dione, reduction, hepatic insulin receptor (23E)-cucurbita-5,23,25-triene-3,7- substrate and phosphoinositide-3 dione, and (23E)-5β,19-epoxycucurbita- kinase interactions increase 6,23-diene-3β,25-diol: cucurbitane-type Seed: protein synthesis triterpenes; 3β,25-dihydroxy-7β- inhibition methoxycucurbita-5,23(E)-diene, 3β- hydroxy-7β,25-dimethoxycucurbita- 5,23(E)-diene, 3β,7β,25- trihydroxycucurbita-5,23(E)-dien-19-al, and 25-methoxy-3β,7β- dihydroxycucurbita-5,23(E)-dien-19-al, (23E)-5β,19-epoxy-25- methoxycucurbita-6,23-dien-3β-ol: triterpenes Dried vines + leaf. Kuguacins F–S, momordicine I, kuguacin E, , 5b,19- epoxycucurbita-6,23-diene-3b,19,25- KURTZIANA triol, karavilagenin D, 3b,7b,25- trihydroxycucurbita-5,(23E)-dien-19-al, 3b,7b-dihydroxy-25- methoxycucurbita-5,(23E)-dien-19-al

BARBOZA, G.E.etal.MedicinalfloraofArgentina Momordica charantia L. Fruit. Karavilagenins A, B, and C: (continuation) cucurbitane-type triterpene, 19(R)- methoxy-5β,19-epoxycucurbita-6,23- dien-3β,25-diol and 5,19- epoxycucurbita-6,23-diene-3,25-diol; karavilosides I, II, III, IV, and V, goyaglycosides a, b, -c, -d, -e, -f, -g, -h, momordicosides F1, F2, A, C, G, I, K, L: cucurbitane-type triterpene glycosides; goyasaponins I, II, III: oleanane-type triterpene saponins; arabinose, rhamnose, xylose, galactose, glucose, galacturonic Seed. Momordin, agglutinin, trichosanthin; aspartic, threonine, serine, glutamic, glycine, alanine, valine, cysteine, methionine, leucine, tyrosine, phenylalanine, lysine, arginine: aminoacids CUNONIACEAE Caldcluvia paniculata Leaf: anticatarrhal and against No biological test No data (Cav.) D. Don urinary disorders Tiaca, triaca, quiaca CHU, NEU, RNE Soriano 1359 (SI) Weinmannia trichosperma Leaf and bark: astringent, Leaf + stem: cytotoxic activity No data Cav. balsamic, antidiarrheal, vulnerary Tineo, teniú, teñiu, tiñeo, tinel CHU, NEU, RNE, SCR Cabrera 21212 (LP) CUSCUTACEAE Cuscuta campestris Yunck. Stem and leaf: diuretic, purgative, Whole plant: analgesic, Tissue. Polygalacturonase Cuscuta chica, cuscuta antitussive hypothermic, antiinflammatory, chilena, yuyo tumbador (sub nom. C. pentagona var. and CNS-depressant activity Cuscuta pentagona var. calycina) calycina Engelm. BAI, CHU, COR, DFE, ERI, JUJ, Hunziker 5690 (CORD) MEN, NEU, RNE, SAL, SCR 195

196 Cuscuta chilensis Ker-Gawl. Fresh entire plant: to treat Dried entire plant: anti- Entire plant. Sophoranol, matrine, n- Boelcke 13816 (BAA) tumors; infusion: diuretic, inflammatory and antipyretic methyl cytisine: quinolizidine alkaloids Tomo34(1-2):7-365.2009 abortifacient. activity, toxic effect (general) Part not specified, infusion: emmenagogue MEN, NEU Cuscuta grandiflora Kunth Aerial parts: general pain, against Dried aerial parts: antimalarial No data Barboza 1283 (CORD) snakebites, to abort activity CAT, JUJ, SAL, TUC Cuscuta obtusiflora Kunth Stem: diuretic No biological test No data Cipó chumbo Flowers, infusion: emmenagogue Stuckert 20043 (CORD) BAI, COR, COS, ERI, MEN, MIS, SFE, TUC DESFONTAINIACEAE Desfontainia fulgens D. Don Leaf: sedative No biological test No data Taique NEU, RNE, SCR, TDF Desfontainia spinosa Ruiz & Pav. Cabrera 6024 (LP) ELAEOCARPACEAE Aristotelia chilensis Fruit + leaf: respiratory disorders, Stem + leaf: antimicrobial, and Stem + leaf. Aristoteline, aristotelone, (Molina) Stuntz kidney disorders, antidiarrheal, cytotoxic activity aristotelinine, aristone, aristotelinone, Maqui, maquel, queldrón, antidysenteric, vulnerary, Leaf: antioxidant activity makonine, 8-oxo-9-dehydrohobartine, queldón, clon, codón astringent, to relieve fever and to 8-oxo-9-dehydromakomakine, Cocucci 2133 (CORD) treat mouth ulcers and intestinal aristoquinoline, makomakine, tumours, dermatologic hobartine, serratoline: alkaloids CAT, CHU, LPA, LRI, MEN, NEU, RNE, SJU, SLU EMPETRACEAE Empetrum rubrum Vahl ex Part not specified: medicinal No biological test Leaf. Quercetin 3-arabinoside,

Willd. CHU, MEN, NEU, RNE, SCR, quercetin 3-galactoside, quercetin 3- KURTZIANA Brecillo, murtilla TDF rutinoside, gossypetin 3-galactoside: Cocucci 2505 (CORD) flavonoids; p-coumaroylquinic acid, chlorogenic acid Fruit. Cyanidin and peonidin glycosides

BARBOZA, G.E.etal.MedicinalfloraofArgentina ERICACEAE Gaultheria erecta Vent. Whole plant: for bronchitis and Aerial parts: antibacterial No data Huevito de gallina, mullaca asthma activity Morrone 3865 (SI) JUJ, SAL Gaultheria insana (Molina) Fruits: narcotic No biological test Leaf. Quercetin, myricetin D. J. Middleton CHU Looser 1198 (SI) Gaultheria mucronata (L. Fruit: medicinal Aerial parts: antischistosomal Leaf. Quercetin, kaempferol, myricetin, f.) Hook. & Arn. var. CHU, NEU, RNE, SCR, TDF effect hydroquinone mucronata Aerial part essential oil. Ocimine, Pernettya mucronata (L. f.) cadinen, farnesen, germacren, Gaudich. ex Spreng. germacrol, bisabolol, apiol, estragol, Cocucci 463 (CORD) carveol, thymol, menthofuran Gaultheria phillyreifolia Entire plant: febrifuge, antiseptic, No biological test No data (Pers.) Sleumer vulnerary Chaura, murtilla BAI, CHU, NEU, RNE Hosseus 1492 (CORD) ESCALLONIACEAE Escallonia megapotamica Medicinal No biological test No data var. spiraeifolia (Cham. & BAI, COS, ERI, MIS Schltdl.) Sleumer Chachacoma Fortunato 8039 (BAB, SI) Escallonia myrtoidea Part not specified: cathartic, tonic, Aerial parts: angiotensin- Dried aerial parts. Asperuloside, Bertero ex DC. vulnerary converting enzyme inhibition daphylloside: iridoid monoterpene Luma MEN Araque 1287 (LIL) Escallonia rubra (Ruiz & Flowers + leaf: tonic, Leaf + stem: cytotoxic and No data Pav.) Pers. var. rubra emmenagogue, vulnerary antitumor activity Siete camisas colorada, siete Part not specified: hepatic camisas disorders Bernardello 597 (CORD) CHU, NEU, RNE, SCR Escallonia tucumanensis Flowers + leaf: tonic, No biological test No data

Hosseus emmenagogue, vulnerary 197 Lillo 5454 (LIL) CAT, JUJ, LRI, SAL, TUC

198 Escallonia virgata (Ruiz & Part not specified: hepatic No biological test No data Tomo34(1-2):7-365.2009 Pav.) Pers. CHU, NEU, RNE, SCR, TDF Meki Barboza 1206 (CORD) EUPHORBIACEAE Acalypha communis Müll. Leaf: detergent, for treating Dried aerial parts: antibacterial Dried aerial parts. 16 α- Arg. wounds externally, cicatrizant and antioxidant activity hydroxymollic, 15 α-hydroxymollic, 7 Albahaquilla, albahaquilla del BAI, CHA, COR, COS, ERI, FOR, β-,16 β-dihydroxy-1,23-dideoxyjessic campo JUJ, LPA, MIS, SAL, SFE, TUC acids: cycloartane-type triterpenes Bernardello 361 (CORD) Acalypha poiretii Spreng. Medicinal No biological test No data Hunziker 12282 (CORD) CAT, CHA, COR, JUJ, SAL, SDE, SJU, SLU, TUC Astraea lobata (L.) Klotzsch Entire plant, infusion: to sterilize Root + aerial parts: Leaf + stem. Vomifoliol: Croton lobatus L. females; to cure malaria, antiplasmodial and cytotoxic sesquiterpene; lobaceride (3- Hunziker 9102 (CORD) pregnancy troubles, and dysentery activity (sub nom. C. lobatus) [(6Z,9Z)dodeca-6,9-dienoyloxy]-2- Seed: purgative octanoyloxypropyl (6Z,9Z)dodeca-6,9- (sub nom. C. lobatus) dienoate): triglyceride; COR, ERI, FOR, JUJ, MIS, SAL, (Z,Z,Z)-9,12,15-octadecatrienoic acid SDE, TUC methyl ester, 8,11,17,21-tetramethyl- (E,E,E,E)-8,10,17,21- tetraentetracosanoic acid, geranylgeraniol, cholestan-3-one, betulinic acid, (E)-3-(4-methoxy- phenyl)-2-phenyl-acrylic acid (sub nom. C. lobatus) Cnidoscolus albomaculatus Aerial parts: anti-inflammatory No biological test No data (Pax) I. M. Johnst. CHA, COS, JUJ, MIS, SAL, TUC Ortiga brava Múlgura 2028(SI) KURTZIANA Cnidoscolus loasoides (Pax) Medicinal No biological test No data I.M. Johnst. CHA, COS, MIS Cocucci 3079 (CORD)

Cnidoscolus tubulosus var. Sap: bruises, boils, tooth pain, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina trilobus (Müll. Arg.) paye´s use Lourteig & O´Donell CAT, COR, FOR, JUJ, LRI, SAL, Ahumada 4485 (SI) SJU, TUC Cnidoscolus vitifolius var. Leaf: anesthesic No biological test Stem. 3-acetyl aleuritolic acid, 3β- cnicodendrum (Griseb.) JUJ, LRI, SAL acetyl-, cinnamoyl- and Lourteig & O´Donell dihydrocinnamoyl-lupeol, 3β-hexanoyl Zuloaga 7665 (SI) lupeol Colliguaja integerrima Bark: against toothache Leaf + stem: antibacterial, Aerial parts. Lupeol, β-sitosterol, Gillies & Hook. CHU, LRI, MEN, NEU, RNE, anticancer and cytotoxic activity ursolic acid, oleanolic acid, Duraznillo, colihuai, colihui, SCR, SJU Seed oil. Arachidic acid, palmitic acid, colihuasi, coliguay oleic acid: lipids Cocucci 3569 (CORD) Croton argentinus Müll. Aerial parts: digestive Aerial parts: antioxidant No data Arg. BAI, COR, SLU activity Ahumada 7011 (CTES) Croton bonplandianus Part not specified: cephalalgic Entire plant: antispasmodic Leaf. Crotosparine, crotosparine: Baill. Entire plant, infusion: antiseptic activity isoquinoline alkaloids Nogal del zorro, paloma Dried aerial parts: vermifuge, Dried flower, leaf, seed + stem: yuyo, piñoncito, escoba negra antidiarrheal, hepatic, stomachache larvicidal activity Hunziker 12336 (CORD) Fresh leaf + stem: as a poultice Fresh latex: antifungal activity for inflammed joints Seed: antibacterial activity CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Croton hieronymi Griseb. Aerial parts: digestive, stomachic Dried aerial parts: cytotoxic Dried aerial parts. α-and β-amyrin: Poleo del monte CAT, FOR, JUJ, SAL, SDE, SFE, activity triterpenes; C-25 analog of trans-phytol, Hunziker 1063 (CORD) TUC Shoot: anticancer activity squalene derivative all-trans- Leaf + root essential oil: 2,6,15,19,23-pentamethyltetracosa- antimicrobial activity 2,6,10(28),14,22,28-hexaene-11-ol, all- trans-10-methylene-2,6,10,14,18,22- pentamethyltetracosa-1,6,10,14,18,22- hexaen-3-ol; epicubenol, τ-cadinol: sesquiterpenes; xanthoxylin: acetophenone derivative; aurentiamide acetate, N-benzoylphenylalanyl-N- 199 benzoylphenylalaninate: peptide derivatives

200 Croton hieronymi Griseb. Shoots essential oil. τ-cadinol, (continuation) epicubenol: sesquiterpenes; Tomo34(1-2):7-365.2009 xanthoxylin: acetophenone Shoots. α- and β-amyrin, lupeol, hop- 22(29)-en-3β-ol, squalene derivatives all-trans-10-methylene-2,6,10,14,18,22- hexaen-3-ol and 2,6,15,19,23- pentamethyltetracosa- 2,6,10(28),14,22,28-hexaene-11-ol, cholesterol, cholest-8(14)-en-3β-ol, stigmasterol, gramisterol, sitosterol, campesterol, 22-dihydrobrassicasterol, lophenol, isofucosterol, stigmasterol, cholest-4-en-3-one, ergosta-4-22-dien- 3-one, sitostenone Leaf essential oil. Camphor, borneol Root essential oil. Euasarone, asarone, borneol, camphor Croton lachnostachyus Baill. Dried stem bark: to treat cancer Dried bark: analgesic activity Root. Junceic acid; yucalexins B-6 and Croton sarcopetalus Müll. Seed: purgative Dried sap: antidiarrheal activity P-4, sarcopetaloic acid, sarcopetal-15- Arg. Dried resin, decoction: to treat (sub nom. C. sarcopetalus) en-3-one-12,13-olide, sarcopetal-15-en- Bernardello 370 (CORD) urinary tract infections, antidiarrheal 3b-ol-12,13-olide (sub nom. C. (sub nom. C. sarcopetalus) sarcopetalus) CAT, CHA, COR, COS, ERI, Dried stem bark. Aleuritolic acid acetyl: FOR, JUJ, LRI, MIS, SAL, SDE, triterpene; barbascoatic acid,12-epi: methyl SFE, SLU, TUC ester, cleroda-3-13(16)-trien-2-one,15-16- epoxy: diterpenes (sub nom. C. sarcopetalus) Root essential oil. Trans-

methylisoeugenol, with 22 further KURTZIANA compounds Croton parvifolius Müll. Arg. Part not specified: digestive No biological test Essential oil. Elemicin: Siete estrellas, yerba de la BAI, CHA, COR, ERI, SDE, SFE, phenylpropanoid; humulene: gama SLU sesquiterpene Hunziker 6238 (CORD)

Croton saltensis Griseb. Seed: purgative No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Renvoize 3461 (SI) JUJ, SAL, TUC Croton subpannosus Müll. Leaf: expectorant No biological test No data Arg. ex Griseb. CHA, COR, COS, ERI, FOR, MIS, Bálsamo, bálsamo del campo, SAL, SFE, TUC turuví Hunziker 13418 (CORD) Croton urucurana Baill. Bark: cicatrizant, analgesic, Stem bark essential oil: Plant. Acetyl aleuritolic acid: Sangre de drago, urucurá, stomachic, anti-ulcer, antidiarrheal, cytotoxicity, antioxidant, and triterpene; stigmasterol, β-sitosterol, ivirá-caá-berá anti-inflammatory good antimicrobial activity campesterol, β-sitosterol-O-glucoside Hunziker 5433 (CORD) Leaf: astringent, resolutive, for Red latex: antidiarrheal, Stem bark. Sonderianin, 15,16-epoxy- treatment of cancer antioxidant, antibacterial, and 3,13(16)-clerodatriene-2-one and 12- Seeds and bark: curative mouth antifungal activity epi-methyl-barbascoate: furane ulcers in infants clerodanes CHA, COS, ERI, FOR, MIS, SF Stem bark essential oil. Borneol, bornyl acetate, cadina-4,10(14)-dien- 1a-ol, sesquicineole, γ-gurjunene epoxide Leaf essential oil. Germacrene-D, bicyclogermacrene Latex. Proanthocyanidins, Gum exsudate. Furanoarabinogalactan: polysaccharide Euphorbia caespitosa Lam. Stem: drastic, diuretic, anti- No biological test No data var. caespitosa asthmatic, expectorant Hunziker 3836 (CORD) BAI Euphorbia collina var. Latex: toxic, caustic, against the Plant: proteolytic activity Plant. Serine-type peptidases (sub nom. andina (Phil.) Subils cutaneous warts (sub nom. E. collina) E. collina); quercetin: flavonol; tannic Kurtz 5571 (CORD) MEN, NEU, SCR acid

Euphorbia helioscopia L. Entire plant: for cancer Aerial parts: hypothermic and Fresh entire plant. Carpinusin: tannin Lechetrés Dried aerial part, infusion: for irritant activity Aerial parts. Astragalin: flavonol; Subils 991 (CORD) chronic bronchitis Dried leaf: molluscicidal chlorogenic acid: phenylpropanoid; Dried root: laxative activity glucogallin: benzenoid

Fresh latex: used for eczema, Dried resin: irritant activity Fresh leaf + root. Euphohelin 201 emollient, toxic, caustic, against Latex: proteolytic activity Latex. Proteases the cutaneous warts BAI, COR, DFE, LPA, MIS

202 Euphorbia heterophylla L. Dried entire plant, infusion: Entire plant: laxative effect Leaf. Alanine, aspartic acid, cysteine, Tomo34(1-2):7-365.2009 Hunziker 1865 (CORD) hemostatic, purgative glutamic acid, methionine, proline, Root: emetic serine: aminoacids; amyrin: triterpene Leaf: to induce lactation Leaf + stem. Alkaloids, tannins, Flowers + leaf: pectoral, terpenoid, flavonoids, phlobatannin, antimicrobial; cardiac glycoside infusion: purgative COR, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Euphorbia hirta var. Part not specified: diuretic, Aerial parts: immunostimulant Aerial parts. Inositol; linoleic acid: ophthalmica (Pers.) Allem & cicatrizant activity, smooth muscle lipid; ˜ sitosterol: steroid Irgang Aerial parts: for wound healing; stimulant; spasmogenic, Dried latex. Amyrin: triterpene; Golondrina, leche de infusion: for asthma, laxative, for hypotensive antitumor, proteases golondrina gonorrhea antimalarial and antibacterial Dried flowers. Ellagic acid: Subils 169 (CORD) Root, infusion: for general fatigue activity Part not specified. Kaempferol: Leaf, infusion: for diarrhea, as a Latex: proteolytic activity flavonol cholagogue, febrifuge; decoction: (sub nom. E. hirta). (sub nom. E. hirta). for asthma Latex: for conjunctivitis, to remove skin warts, for arthritis and rheumatism (sub nom. E. hirta). BAI, CAT, CHA, COR, COS, FOR, JUJ, LPA, MIS, SAL, SFE, TUC Euphorbia klotzschii Leaf + stem: diuretic, antilithic No biological test No data Oudejans var. klotzschii (sub nom. E. ovalifolia) Tupasú cambú, potrillo Latex: to remove skin warts cimarrón. BAI, CAT, CHA, COR, COS, ERI, Euphorbia ovalifolia FOR, JUJ, LPA, LRI, MEN, MIS,

(Klotzsch & Garcke) Boiss. NEU, RNE, SAL, SDE, SJU, SLU, KURTZIANA var. ovalifolia TUC Hunziker 293 (CORD) Euphorbia lasiocarpa Entire plant: contraceptive Fresh leaf + stem: hypotensive No data Klotzsch Fresh latex: for circinate herpes activity Hunziker 13461 (CORD) CAT, CHA, COR, FOR, JUJ, MIS, SAL, SDE, SFE, SLU, TUC

Euphorbia papillosa A. St.- Root: galactogogue No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Hil. var. papillosa COS, ERI, MIS Lechosa, lecherón, mercurio, lechetré Quarín et al. 2257 (CORD) Euphorbia portulacoides L. Root: antiemetic No biological test Dried entire plant. Caudicifolin, var. portulacoides Leaf: vulnerary, dermatologic jolkinolide A: diterpene; Pichoa, lechetrezma, pichoga Latex + root: purgative phloracetophenone,2-4-6-tri-o-methyl Subils 871 (CORD) BAI, CAT, CHU, COR, ERI, JUJ, ether: benzenoid; kauranes, abietane LPA, MEN, SAL, SFE, TUC lactones, phloroacetophenones, latthyranes and abietane acids

Euphorbia portulacoides Root: contraceptive No biological test No data var. acutifolia Boiss. Latex: for warts treatment Palo de leche BAI, CAT, CHA, CHU, COR, Hunziker 15791 (CORD) COS, ERI, JUJ, LPA, MEN, SAL, SLU, TUC Euphorbia prostrata Aiton Entire plant, decoction: for Dried aerial parts: antiyeast Dried entire plant. Alanine: Hunziker 21986 (CORD) delayed periods; infusion: for activity aminoacid; campesterol: steroid bronchial asthma, hypoglycemic Fresh aerial parts: Dried leaf. Corilagin, geraniin: tannin; and kidney inflammation; as a hypoglycemic and anti- alkaloids absent; stigmasterol: sterol snakebite remedy. inflammatory activity Fresh aerial parts, infusion: to Leaf: antiviral activity; protease purify blood; diuretic, against the (hepatitis C virus) inhibition cutaneous warts Dried leaf, infusion: for rheumatism BAI, CHA, COR, COS, ERI, FOR, SFE, TUC Euphorbia sciadophila Part not specified: for earache No biological test No data Boiss. CAT, COR, COS, JUJ, LRI, MIS, Hunziker & Cocucci 15894 SAL, SDE, SLU, TUC (CORD)

Euphorbia schickendantzii Part not specified: against the No biological test Aerial parts. Quercetin: flavonol; 203 Hieron. cutaneous warts, caustic tannic acid Di Fulvio & Subils 263 CAT, CHU, LPA, LRI, MEN, (CORD) NEU, RNE, SCR, SJU

204 Euphorbia serpens var. Aerial parts: diuretic, antilithic No biological test Aerial parts. Quercetin: flavonol; microphylla Müll. Arg. BAI, CAT, CHA, COR, COS, ERI, tannic acid Tomo34(1-2):7-365.2009 Yerba meona, tupasú cambú. FOR, JUJ, LRI, MEN, MIS, NEU, Subils et al. 478 (CORD) SAL, SDE, SFE, SLU, TUC Euphorbia serpens Kunth Aerial parts: diuretic Aerial parts: antibacterial Leaf. Alkaloids absent var. serpens Dried leaf + stem, infusion: for activity Yerba meona, rompepiedras, eye diseases lechetrés, meona, yerba de la Latex: caustic, against the golondrina cutaneous warts, for circinate Subils 4598 (CORD) herpes Part not specified: for skin diseases (sub nom. E. serpens) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, TUC Jatropha curcas L. Dried entire plant: purgative Dried aerial parts: antifungal Leaf + twigs. α-amyrin: triterpene; Piñón, piñón del diablo Bark: for pyorrhea activity, toxic effect; wound- apigenin: flavone; caniojane: diterpene Venturi 10772 (SI) Dried bark + stem, decoction: for healing activity Leaf + bark. Glycosides, tannins, inflammation Dried fruit: anti-implantation phytosterols, flavonoids, steroidal Leaf, decoction: febrifuge; effect, antibacterial activity sapogenins infusion: for urinary tract Latex: antimicrobial and Dried root. Curcusone a: diterpene infections, dysentery (amebiasis), proteolytic activity Seed. Curcin: protein; oleic acid: lipid chronic ulcers Latex. Jatrophidin I, pohlianin A, Capsule, latex: to treat athletes cyclogossine A foot. Seed + entire plant: drastic purgative, anti-haemorrhoidal COS, JUJ, MIS, SAL

Jatropha excisa Griseb. Seed: drastic, emetic No biological test No data KURTZIANA Higuerilla, sacha higuera CAT, COR, COS, FOR, LRI, SAL, Hunziker 13497 (CORD) SDE, SFE, SJU, SLU, TUC Jatropha flavovirens Pax & Sap: Medicinal No biological test No data K. Hoffm. COR, LRI, SAL Hunziker 11684 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Jatropha grossidentata Pax Entire plant: allergenic Root: antiprotozoal activity Dried root bark. Caniojane, & K. Hoffm. Bark: anthelmintic jatrogrossidione: diterpene Jwetósek, kadýohã CHA, FOR, SAL Tolaba 2774 (CORD) Jatropha hieronymi Kuntze Sap: tooth pain No biological test No data Cabrera et al. 32265 (SI) CAT, JUJ, LRI, SAL, SDE, SJU Jatropha isabelliae Müll. Root, infusion: for fertility Rhizome: gastroprotective effect Rhizome. Jatrophone, jatropholone A, Arg. regulation antisyphilitic, jatropholone B, acetyl aleuritolic acid, Yagua rova abortifacient, antisdysenteric; cyperenoic acid, 9β,13- Jatropha isabelliae var. against malaria dihydroxyisabellione antisyphilitica (Speg.) Pax COS, MIS Burkart 18740 (SI) Jatropha macrocarpa Seed: purgative, emetic No biological test No data Griseb. CAT, JUJ, LRI, SAL, SDE, SLU, Higuera del zorro, ortigón TUC bravo macho Kiesling 4307 (SI) Jatropha pedersenii Medicinal No biological test No data Lourteig COS Cocucci 3096 (CORD) Manihot anisophylla Müll. Seed: drastic, emetic No biological test No data Arg. CAT, COR, LRI, SAL, SJU, SLU, Hunziker 24678 (CORD) TUC Manihot grahamii Hook.. Plant: drastic No biological test No data Falso café, cafeto Seed: toxic Di Fulvio 167 (CORD) Part not specified: for skin eruptions BAI, CAT, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC Sapium haematospermum Bark: vulnerary Dried aerial parts: Dried aerial parts. Astragalin: Müll. Arg. Leaf, decoction: for antimycobacterial and flavonol; lecheronol: diterpene; 1- Lecherón, curupí, blanquillo, gastrointestinal pains, febrifuge antimalarial activity olean-12-ene,3-α-hydroxy: triterpene; palo de leche, árbol de leche, Fresh latex: for toothache Latex: proteolytic activity lecheronol A and B: pimaranes; 3-O-β- curupí-caí BAI, CAT, CHA, COR, COS, lauroyl-cycloart-(23E)-en-25-ol (10): Hunziker 10494 (CORD) DFE, ERI, FOR, JUJ, MIS, SAL, acylated cycloartane; α,β,3,4,5,2',4',6'- SDE, SFE, TUC octahydroxydihydrochalcone (12): ; triterpene derivatives; 205 flavonol glucosides

Sebastiania brasiliensis Aerial part: galactogene (sub Leaf: antimicrobial and antiviral Leaf + stem. Methyl gallate, 206 Spreng. nom. S. anisandra) activity protocatechuic acid, quercetin, Tomo34(1-2):7-365.2009 Lecherón, blanquillo, ibirá Bark, leaf + twigs: antiseptic for kaempferol, quercitrin, gallic acid camby, ibirá-cambú, leche- wounds, analgesic for dental leche caries anisandra Latex: against the cutaneous warts, (Griseb.) Lillo for toothache Novara 10952 bis (CORD) Part not specified: for spider bites BAI, CAT, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Sebastiania commersoniana Aerial parts: antiseptic, analgesic Aerial parts: antioxidant Aerial parts. Quercetin, kaempferol, (Baill.) L. B. Sm. & Downs for dental caries, antimicrobial activity isorhamnetin, isoquercitrin: flavonoids; Blanquillo, lecherón BAI, COR, COS, ERI, JUJ, MIS, Leaf: antimicrobial and antiviral gallicin, gallic, syringic, caffeic acids: Sebastiania klotszchiana SAL, TUC activity (sub nom. S. phenolic derivatives; scopoletin: (Müll. Arg.) Müll. Arg. klotszchiana) coumarin Subils 2776 (CORD) Stillingia patagonica (Speg.) Entire plant: proteolytic activity Plant: proteolytic activity Plant. Cysteine-type peptidases Pax & K. Hoffm. CHU, MEN, NEU, RNE, SCR Mata torcida, mata crespa, retamillo Steibel 4535 (CORD) Tragia geraniifolia Klotzsch Root: emollient, rubefacient No biological test No data ex Baill. Part not specified: diuretic, Ortiga, ortiga brava, ortiga antirheumatic del campo, ortiga quemadora BAI, CAT, CHA, COR, COS, ERI, Subils 4037 (CORD) FOR, JUJ, LRI, SAL, SFE, SJU, SLU Tragia volubilis L. Root: diuretic No biological test No data Barboza 750 (CORD) BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, MIS, SAL, SDE, SFE, KURTZIANA TUC FABACEAE Acacia albicorticata Burkart Bark: for wounds, cuts No biological test No data Espinillo blanco, espino Flower: for cough, bronchitis blanco, tusca blanca JUJ, SAL, TUC Legname 7579 (CTES)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Acacia aroma Gillies ex Aerial parts: for haemorrhages; Stem, leaf + flower: Dried leaf. Apigenin, rhamnetin, Hook. & Arn. cicatrizant, disinfectant, and for the antibacterial and antioxidant cynaroside: flavone; linamarin: alkanol Tusca, espinillo, espinillo, treatment activity to C4 aromita, paaic, aromo, aromo of gastrointestinal disorders negro, bais Dried branches, decoction: to Hunziker 22833 (CORD) treat urinary and respiratory tract infections Root, decoction: antiseptic Bark: abortive, diuretic, cicatrizant, for hernia and prolapse, used in pregnancy and facilitate birth, post partum pains and diseases, anti-inflammatory Leaf + fruit: antiseptic for venereal disease, antacid, cicatrizant Flowers + leaf: antitussive, against influenza Seed, bark + leaf: astringent, antiseptic CAT, CHA, COR, COS, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Acacia atramentaria Benth. Leaf + bark: detergent, vulnerary, Whole plant: antimicrobial Dried leaf. Acacipetalin: alkane to C4 Espinillo bravo, espinillo antirheumatic activity negro, espinillo fuerte, Seed + leaf: astringent, antiseptic, hurquillo, garabato negro, antitussive tusca BAI, CHA, COR, COS, ERI, FOR, Hunziker 15826 (CORD) JUJ, MEN, SAL, SDE, SFE, SJU, SLU, TUC Acacia bonariensis Gillies Bark: cicatrizant No biological test Aerial parts. Heterosides, tannins ex Hook. & Arn. Stem + root: depurative, Ñapinday, ña pindá, ñapindá antisiphylitic blanco, garabato, uña de gato BAI, CAT, CHA, COR, COS, ERI, Stuckert 21488 (CORD) FOR, JUJ, MIS, SFE, SJU, TUC 207

Acacia caven (Molina) Root: purgtive Leaf + stem: cytotoxic, Dried leaf. Quercetin, quercitrin: 208 Molina var. caven Bark: detergent, cicatrizant, antimicrobial, and antifungal flavonol Espinillo, aromo, churqui, antidiarrheal activity Essential oil. Anisaldehyde: benzenoid; Tomo34(1-2):7-365.2009 aromito, aromita, cavén, Dried leaf + stem: antiseptic; to Dried seed: β-glucuronidase bornyl acetate, linalool: monoterpenes; espino treat hypertension, diabetes, skin inhibition eugenol: phenylpropanoid Hunziker 17446 (CORD) mycosis and irritations, cicatrizant Leaf, decoction: antidiarrheal, diuretic Flower: sedative Seed + leaf: astringent, antiseptic, anti-asthmatic, antitussive BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Acacia caven var. microcarpa Leaf: for treating wounds No biological test No data (Speg.) Burkart ex Ciald. externally Aromita CHA, FOR Krapovickas 94 3 (SI) Acacia caven var. Leaf, decoction: antidiarrheal and No biological test No data stenocarpa (Speg.) Burkart for whooping cough ex Ciald. CHA, ERI, FOR, MIS, SFE Hunziker 5749 (CORD) Acacia farnesiana (L.) Bark, infusion: febrifuge, Dried leaf: antibacterial activity Essential oil. Anisaldehyde, Willd. astringent Fresh flower, fruit, leaf + stem: benzaldehyde: benzenoid, cumin Espinillo Dried bark + root, infusion: for antiphage activity alcohol, cuminaldehyde; geraniol, Lahitte s.n. (BAB 60295) dermato-mucosal lesions Dried flowers: uterine stimulant geranial, neral Leaf, infusion: for gonorrhea effect Dried leaf. Tannin Flowers, infusion: aphrodisiac Essential oil: hypotensive Fruit. Cystine: quinolizidine alkaloid Dried fruit, infusion: for diabetes activity Dried seed. Daucosterol: steroid; mellitus diosmetin: flavone

CHA, COR, FOR, MIS KURTZIANA Acacia macracantha Humb. Bark: for hernia and prolapse Leaf. Phenols; condensed tannins; & Bonpl. ex Willd. CHA, COR, JUJ, SAL, SDE, SFE, saponins; alkaloids Tusca, cují hediondo TUC Gum. Hydroxyproline, serine, lysine; Fabris 3490 (LP) rhamnose, arabinose, galactose, glucuronic acid and its 4-O-methyl analogue

BARBOZA, G.E.etal.MedicinalfloraofArgentina Acacia martii Benth. Leaf: antirheumatic No biological test No data Muello s.n. (LP) FOR Acacia praecox Griseb. Part not specified: central nervous No biological test Leaf. Flavonoids Garabato, espinillo de Santa system stimulant Flowers essential oil. Linalol, Fé, espinillo macho, ñapindá, CAT, CHA, COR, COS, ERI, undecane, eugenol, decane, oct-1-en-3- añapindá, garabato negro FOR, JUJ, SAL, SDE, SFE, TUC ol Hunziker 17729 (CORD) Adesmia boronioides Hook. Aerial parts: for kidney and Aerial parts essential oil: Aerial parts essential oil. Esquel-6-en- f. respiratory disorders, ulcers, leukotriene B-4 inhibition 9-one,1(R)-4(S)-5(R), esquel-7-en-9- Paramela, yagneu, loncko- digestive, febrifuge, against the Dried aerial parts: one: bisnorsesquiterpenes; α-copaen- trevo, té pampa, té silvestre, influenza, antitussive, prostaglandin E2 inhibition; 11-ol, δ-cadinene, 10-epi-γ-eudesmol, yerba carmelita, éter antirheumatic, for allopecy, burns antibacterial activity 4α-hydroxydihydroagarofuran, 1-epi- Cocucci 2528 (CORD) and bruises, stomachic, analgesic, cubenol, α-pinene anti-inflammatory aphrodisiac CHU, NEU, RNE, SCR, TDF Adesmia emarginata Clos Part not specified: stomachic No biological test No data Paramela NEU Kurtz 6209 (CORD) Adesmia inflexa Griseb. Root: cough, parturition pains No biological test No data Añaguá CAT, JUJ, LRI, SAL, TUC Cocucci 2004 (CORD)

Adesmia subterranea Clos Part not specified: ophtalmic No biological test No data Cuernos de cabra, cuerno LRI, MEN, SJU Kurtz 9673 (CORD) Aeschynomene rudis Benth. Part not specified: anaphrodisiac No biological test No data Pedersen 12788 (CTES) BAI, CHA, ERI, FOR, MIS, SFE Albizia inundata (Mart.) Leaf: for treating wounds Leaf: fungicidal activity No data Barneby & J.W Grimes BAI, CHA, COS, ERI, FOR, JUJ, Visco, pacará, timbó blanco, MIS, SAL, SFE palo flojo, timbó atá, timboí, timbó y, timboí atá, timbó morotí, ngehñú Troncoso 1364 (SI) 209

Amburana cearensis Part not specified: for respiratory Dried stem bark: relaxant Dried stem bark. Amburoside A: 210 (Allemão) A. C. Sm. ailments action; antimalarial activity; benzenoid; α-amyrin: triterpene; Roble del país, roble JUJ, SAL neuroprotective properties coumarin; Tomo34(1-2):7-365.2009 paraguayo, palo de trébol Dried trunk bark: toxic effect kaempferol, isokaempferide, Zabala 111 (SI) (general) protocatechuic acid Anadenanthera colubrina Dried branches: for leg Dried branches: radical Dried aerial parts. Alnusenol: var. cebil (Griseb.) Altschul inflammation scavenging effect; lipoxygenase triterpene; anadanthoflavone, alnusenol, Cebil, cebil colorado, yopo, ce- Bark: abortive, astringent, inhibition lupenone, lupeol, betulinic acid, α- bil moro, vilca, cohoba, curu- depurative, antittusive, (sub nom. A. colubrina) amyrin, β-amyrin, β-sitosterol, pay, cebil moro, cebil colorado expectorant, and for infections Bark: anti-inflammatory activity stigmasterol, apigenin, 4- verrucoso, cebil blanco Part not specified, infusion: Gum: immunological activity hydroxybenzoic acid, cinnamic acid Piptadenia macrocarpa emmenagogue, hallucinogenous Heart wood. Dalbergine, 3,4,5- Benth. Gum: for respiratory problems dimethoxy-3-dalbergione, 5-methoxy- Anadenanthera macrocarpa Seed: abortive, for heart problems N-methyl-tryptamine (Benth.) Brenan (sub nom. A. colubrina) Dried bark. Anadanthoside: flavonoid; Hunziker 21469 (CORD) CAT, CHA, COR, COS, ERI, cinnamic acid: phenylpropanoid FOR, JUJ, MIS, SAL, SDE, TUC Gum: galactose, arabinose: acidic heteropolysaccharides Seed. Bufotenine, N-N-dimethyl- tryptamine: indole alkaloids Anarthrophyllum Plant, infusion and juice: Aerial parts: cytotoxic activity No data desideratum (DC.) Benth. expectorant, for gastritis Neneo macho, mata fuego, CHU, SCR bola de fuego Illin 108 (SI) Astragalus garbancillo Cav. Dried entire plant, infusion: for No biological test Seed. Swainsonine: alkaloid Garbancillo, porotillo, purko acariasis and dandruff Barboza 1324 (CORD) Leaf + stem: for fractures Dried seed, infusion: for urticaria Part not specified: to cure smashed bones and sprains CAT, JUJ, LRI, MEN, SAL, SJU, TUC KURTZIANA Ateleia glazioveana Baill. Part not specified: insecticide, toxic No biological test No data Spegazzini 12015 (SI) MIS Bauhinia argentinensis Bur- Leaf: hepatic, kidney disorders No biological test No data kart var. argentinensis FOR, SAL Pata ‘e buey, pata de vaca Horovitz 111 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Bauhinia bauhinioides Leaf: refrigerant, diuretic Seed. Inhibitory activity of Seed. Protein with 164 amino acid (Mart.) J. F. Macbr. FOR cruzipain, a cysteine proteinase residues Pata de vaca from Trypanosoma cruzi Fortunato 2509 (BAB) Bauhinia forficata subsp. Leaf: antidiabetic, astringent, Dried leaf: hypoglycemic, Dried leaf. 3,7-di-O-a- pruinosa (Vogel) Fortunato diuretic, expectorant, antinephritic, antioxidant, rhamnopyranosylquercetin and 3,7-di- & Wunderlin antitussive, antihemorrhoidal, hypocholesterolemic (lowers O-a-rhamnopyranosylkaempferol Pezuña de vaca, pata de vaca, abluent, blood depurative cholesterol), diuretic, and (kaempferitrin): flavonoids; astragalin, caobá, mahogani, pata de Flowers: antihemorrhoidal, antimicrobial activity; bauhinoside, guanidine, buey, pata de chivo, pata de digestive, external use against cardiovascular effect heteroglycosides, kaempferitrin, toro, falsa caoba, palo buey, dandruff (tachycardia) organic acids, quercitrosides, rhamnose, toro-p BAI, CAT, CHA, COR, COS, Stem, fruit + seed: antibacterial saponins, alkaloids, glycosides B. candicans Benth. DFE, ERI, FOR, JUJ, LPA, MEN, activity Leaf + flowers. Sitosterol, campesterol, Ariza Espinar 3378 (CORD) MIS, SAL, SFE, SJU, TUC stigmasterol, cholesterol, stigmast-3,5- dien-7-one, choline, trigonelline, sitosterol 3-O-β-glucoside, sitosterol 3- O-β-D –xylopyranoside, sitosterol 3-O- α-D -xyluronofuranoside (sub nom. B. candicans) Bauhinia microstachya Part not specified: for spleenache, Leaf: analgesic, antioxidant and Leaf. Methyl gallate, kaempferol 3-O- (Raddi) J. F. Macbr. to relieve the lumbago, analgesic free radical scavenging activity; rhamnosyl, quercitrin, , Escalera de mono, cai- COS, MIS antinociceptive action trolox, ascorbic acid, ellagic acid, escalera, tuiá-pihuá, cipó tannic acid, rutin escalera, pata de mono Meyer 6749 (LIL) Caesalpinia gilliesii (Wall. Dried flower + leaf, infusion: Fruit: antitumor activity Dried flowers. phenyl alanine: ex Hook.) D. Dietr. febrifuge, purgative, against Dried seed: respiratory aminoacid; arabinose: carbohydrate Lagaña de perro, algarrobillo, toothache stimulant effect, smooth muscle Seed. Cesalin, glutamic acid, pipecolic piscala, barbón, barba de Dried seed: anthelminthic relaxant activity acid, proline,3-hydroxy: aminoacid viejo, mal de ojos BAI, CAT, CHA, COR, COS, ERI, Ariza Espinar 3025 (CORD) LPA, LRI, MEN, NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC 211

212 Caesalpinia paraguariensis Bark, decoction: antitussive, Dried aerial parts: antibacterial Dried aerial parts. Caesalpinol: (D. Parodi) Burkart digestive, hepatic, antidysenteric; and antioxidant activity benzoxecin derivative; bilobetin, Tomo34(1-2):7-365.2009 Guayacán, ibirá-verá, infusion: antiphlogistic stigma-5-en-3-O-β-6’- alagamia, guayacán Fruit: emollient, contraceptive, stearoylglucopyranoside, stigma-5-en- negroibirá-berá antitussive, anticephallic 3-β-6’-palmitoylglucopyranoside, Hunziker 24344 (CORD) CHA, COR, COS, FOR, JUJ, LRI, stigma-5-en-3-β-glucopyranoside, SAL, SDE, SFE, SLU, TUC oleanolic acid, 3-O-(E)- hydroxycinnamoyl oleanolic acid, betulinic acid, 3-O-(E)- hydroxycinnamoyl betulinic acid, lupeol Heart wood. Tannin Seed. Pipecolic acid: aminoacid Caesalpinia pluviosa DC. Bark: antidiarrheal Stem bark: antiplasmodial No data var. pluviosa SAL activity Taperiba, morochillo Morrone et al. 4597 (SI) Caesalpinia stuckerti Hassl. Root: for intestinal disorders No biological test No data Guaycurú CHA, FOR, SAL, SDE, TUC Novara 11160 (CORD) parvifolia Medicinal No biological test No data (Hook. & Arn.) Speg. BAI, COS, ERI, MIS Plumerillo rosado, flor de seda, flor del cielo, borla de obispo, chicote de niño Cabrera19339 (LP) Camptosema rubicundum Seed: to relieve the vulval pruritis No biological test No data Hook. & Arn. BAI, COS, ERI, MIS Picardía, isipó, capricho, pititos, picardía colorada KURTZIANA Cocucci 2917 (CORD) Canavalia bonariensis Lindl. Leaf: digestive No biological test Dried root. Betulin: triterpene Habas del aire, habas de las BAI, CHA, ERI, JUJ, MIS Dried seed. Lectin: protein víboras, cumandá-guazú Pedersen 9840 (CORD)

Cascaronia astragalina Resin: medicinal No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Griseb. JUJ, SAL, TUC Tipa amarilla, cascarón Juárez 2228 (CORD) Centrosema virginianum Root: emmenagogue, for No biological test No data (L.) Benth. amenorrhea Hunziker 9751 (CORD) CAT, COR, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Cercidium praecox (Ruiz & Bark: antitussive, stomachic, anti-acid No biological test Gum exudate. β-D-glucuronic acid, Pav. ex Hook.) Harms subsp. Dried branches: for cough with arabinose, α-L-furanose, β-L-pyranose praecox vomiting Brea, brea del bordo, palo ver Root bark, infusion: to aid in Hunziker 7804 (CORD) expulsion of placenta CAT, CHA, COR, FOR, JUJ, SAL, SDE, SFE, SLU, TUC Chloroleucon tenuiflorum Bark: anthelmintic, cough, No biological test No data (Benth.) Barneby & J. W. respiratory ailments Grimes CHA, COS, FOR, JUJ, MIS, SAL, Tatané SFE, TUC Martínez 599 (CORD) Copaifera langsdorffii Desf. Part not specified: antivenereus, Dried trunk bark: Dried resin. Kaur-16-en-19-oic var. langsdorffii balsamic, cicatrizant, molluscicidal and antibacterial acid,ent: diterpene Cupay antimicrobial, expectorant, activity Dried leaf essential oil. β-selinene, γ- Rodríguez 795 (SI) diuretic, and antiphlogistic Fruit peel essential oil: anti- cadinene, caryophyllene, copalic acid MIS inflammatory activity Fruit peel essential oil. δ- and β– elemene, α-copaene, 1-gurjuneno, (Z)- caryophyllene, (E)-caryophyllene, aromadendrene, α-humulene, (E)-9-epi- caryophyllene, β-selinene, nerolidol, γ- cadinene, germacrene B, 1,5- epoxisalvial-4(14)-ene, caryophyllene oxide, cis-β-elemenone, humulene oxide, iso spathulenol, farnesol Crotalaria incana L. Leaf: antiseptic Aerial parts: Hypotensive Aerial parts. Mucronatine, usuramine, 213 Schinini 5115 (CTES) CHA, COR, COS, ERI, FOR, JUJ, activity; hepatotoxic, anacrotine: pyrrolizidine alkaloids MIS, SAL, SDE, SFE, TUC pnemotoxic

214 Crotalaria pilosa Mill. Flowers: emollient No biological test No data Morel 575 (LIL) CHA, FOR Tomo34(1-2):7-365.2009 Dalea elegans Gillies ex Part not specified: antimicrobial Root: antimicrobial, antioxidant, Dried aerial parts. 6-prenyl Hook. & Arn. var. elegans COR, JUJ, SAL, SLU and cytotoxic activity pinocembrin: flavanone Hunziker 7288 (CORD) Dried root. 2'-4'-dihydroxy-5'-(1'''- dimethyl-allyl)-6-prenyl pinocembrin,: prenylated flavanone Desmanthus virgatus (L.) Aerial parts: hepatic, antilithic No biological test No data Willd. Root: emetic Rompepiedras BAI, CHA, COS, ERI, FOR, JUJ, Hunziker 13338 (CORD) LPA, MIS, SAL, SDE Desmodium barbatum (L.) Leaf: laxative Dried leaf: antibacterial activity No data Benth. Dried leaf + root, decoction: for Cocucci 3105 (CORD) infections and malaria CHA, COS, MIS Desmodium incanum DC. Part not specified: antitussive No biological test No data Ochoa 1035 (CORD) Leaf: for the kidneys and wounds. Dried leaf + stem, decoction: diuretic, anti-inflammatory CAT, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Dioclea violacea Mart. ex Part not specified: hemostatic No biological test Dried seed. Lectin: protein. Benth. (sub nom. D. paraguariensis) Curuguay CHA, COS, MIS Dioclea paraguariensis Hassl. Venturi 26 (BAB) Enterolobium Bark: analgesic, cicatrizant Seed: pro-inflammatory activity Dried pericarp. Enterolosaponin A, contortisiliquum (Vell.) Leaf: astringent, vulnerary Seed essential oil: antibacterial lupeol: triterpenes KURTZIANA Morong Root, fruit + bark: tonic, against activity Dried seed. Enterolobin: protein Timbó c olorado, pacará, t imbó the scurf, expectorant Seed essential oil. Furfural, limonene, cedro, timbó negro, timbó-puitá, antivenereous linalool, estragole, carvone, apiole, oreja de negro, timbó-cedro BAI, CHA, COS, ERI, FOR, JUJ, carvone Cocucci 1373 (CORD) MIS, SAL, SFE, TUC

Erythrina crista-galli L. var. Stem bark: for dermatosis, anti- Dried aerial parts: Seed. Arginine, alanine, aspartic acid: BARBOZA, G.E.etal.MedicinalfloraofArgentina crista-galli asthmatic, antiseptic, antibacterial, analgesic, anti- aminoacids; erythramine: isoquinoline Seibo, ceibo, ceibo macho, antihemorrhoidal, astringent; inflammatory activity alkaloid seibo entrerriano, choipo decoction: to treat urinary and Dried leaf: antibacterial activity, Leaf. Cristadine, crystamidine: Arbo 6829 (CTES) respiratory tract infections psychotropic agent, CNS isoquinolin; oleanolic acid: triterpene Leaf: hypnotic, sedative, depressor activity antihemorrhoidal, cicatrizant Flowers: expectorant, cicatrizant BAI, CHA, COS, ERI, FOR, JUJ, LPA, MIS, SAL, SDE, SFE, TUC Erythryna dominguenzii Bark: cicatrizant, for injures No biological test Seed. Alanine, aspartic acid: Hassl. CHA, COS, FOR, JUJ, SAL aminoacids; erysopine: isoquinoline Seibo chaqueño, seibo alkaloid formoseño, seibo rosado Fortunato et al. 2030 (BAB) Erythryna falcata Benth. Leaf + bark: galactogene Aerial parts: contraceptive Seed. Alanine, aspartic acid: Seibo salteño, seibo de Jujuy, JUJ, MIS, SAL, SFE, TUC properties aminoacids; erysopine: isoquinoline ceibo, seibito de la selva, alkaloid seibo del monte, ceiba Fortunato 6874 (BAB) Geoffraea decorticans Sprouts: for fractures Bark + branches: bactericidal Dried stem bark. Flavanone, iso: 2'-3'- (Gillies ex Hook. & Arn.) Bark + fruits: emollient, to relieve activity 5-7-tetrahydroxy-4'-methoxy-5'-prenyl: Burkart var. decorticans bruises, anti-asthmatic, antitussive, flavonoid; lupeol: triterpene Chañar to treat urinary and respiratory Dried flowers. Apigenin: flavone; Cocucci 74 (CORD) tract infections, antidiarrheal baicalin: flavone Dried bark + flower, infusion: emollient, expectorant BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, RNE, SAL, SDE, SFE, SJU, SLU, TUC Geoffraea spinosa Jacq. Leaf: anthelmintic Branches: bactericidal activity No data Maní guaycurú, mandubí- (sub nom. G. striata) guaicurú, mandubí-rá, maní CHA, COS, FOR, SAL, SFE de los indios, mandubirá Geoffraea striata (Willd.) 215 Morong Meyer s.n. (SI)

216 Gleditsia amorphoides Leaf + root: astringent Leaf: cytotoxic activity Seed. Glutamic acid, pipecolic acid: (Griseb.) Taub. var. Cortex: to reduce cholesterol aminoacids; triterpene saponins Tomo34(1-2):7-365.2009 amorphoides Fruit: for sores in mouth and Espina corona, algarroba, throat, anti-asthmatic caranchi, coronillo, cambá- Part not specified: for lumbago nambí and kidney pain Hunziker 5806 (CORD) CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE astragalina Plant: medicinal No biological test No data Gillies ex Hook. & Arn. BAI, CHU, COR, LPA, LRI, Regaliz silvestre, orozuz MEN, NEU, RNE, SCR, SJU, Cabrera 32825 (SI) TUC Hoffmannseggia glauca Leaf: astringent No biological test No data (Ortega) Eifert BAI, CAT, CHA, CHU, COR, Porotillo, algarrobilla fina, JUJ, LPA, LRI, MEN, NEU, RNE, papa-cuchi, camincha, cina SAL, SDE, SFE, SJU, SLU, TUC enana, porotillo silvestre Subils 3258 (CORD) Indigofera suffruticosa Mill. Entire plant, decoction: for Dried entire plant: Entire plant. β-sitosterol: sterol; Añil, amaretá, anilcillo, caá- syphilis, against lice, analgesic; anticonvulsant and antiulcer louisfieserone: flavonoid; quercetin 3- hobí infusion: to treat convulsions, for activity; antifungicide activity O-[4’’’-O-α-L-rhamnopyranosyl-β-D- Stuckert 6216 (CORD) dizziness Leaf: antitumor activity xylopyranosyl(1→2)β-D- Aerial parts: anti-epileptic, Fresh seed: molluscicidal galactopyranoside], emollient, to relieve bruises, activity indigo 3-O-β-glucopyranoside and 6’- antiphlogistic, for treating wounds methoxy-2,5,6-trihydroxyisoindirubin, externally, emmenagogue and quercetin 3-O-[β-D- Root: odontalgic, icteric; apiofuranosyl(1→6)β-D- decoction: for epilepsy, for syphilis glucopyranoside], quercetin 3-O-[α-L- Dried stem, decoction: to treat rhamnopyranosyl(1→6)β-D- hepatitis. glucopyranoside], quercetin 3-O-[β-D- Leaf, decoction: febrifuge glucopyranosyl (1→2)β-D- BAI, CAT, CHA, COR, COS, ERI, galactopyranoside], quercetin 7-O-β-D- KURTZIANA JUJ, MIS, SAL, SDE, SFE, TUC glucopyranoside, indican, indigo, indirubin, allantoin, gallic acid, pinitol, sitosteryl 3-O-β-D-glucopyranoside Dried root. Coronarian: alkanol to C4 Dried leaf + stem. Indigo, indirubin: indole alkaloid

BARBOZA, G.E.etal.MedicinalfloraofArgentina Inga affinis DC. Leaf + bark: astringent, Aerial parts: xanthine-oxidase Aerial parts. Ellagic and gallic acids Ingá, ingá negro expectorant, antineuralgic, inhibitors; antioxidant activity (sub nom. I. verna subsp. affinis) Inga verna subsp. affinis antiseptic (sub nom. I. verna subsp. affinis) (DC.) T. D. Penn. Fruits resin: analgesic Tressens 3112 (CTES) COS, MIS Lathyrus magellanicus Part not specified: diuretic No biological test No data Lam. var. magellanicus CHU, LPA, NEU, RNE, SCR, Fortunato 4933 (BAB) TDF Lathyrus pubescens Hook. Leaf: astringent No biological test No data & Arn. var. pubescens BAI, CAT, CHU, COR, COS, ERI, Arvejilla silvestre, alverjilla LPA, RNE, SAL, SCR, SLU, TUC Hunziker 6433 (CORD) Lathyrus subulatus Lam. Leaf: astringent No biological test No data Arvejilla chica, arvejilla BAI, COR, ERI, LPA, MIS, SFE enana Hunziker 8650 (CORD) Lupinus tomentosus DC. Seed: diuretic, emmenagogue No biological test No data West 6331 (GH, MO, UC) Part not specified: emmenagogue JUJ Macroptilium bracteatum Root, decoction: to arrest No biological test No data (Nees & C. Mart.) Maréchal hemorrhage after childbirth, & Baudet hemostatic Poroto del campo CAT, CHA, COR, COS, ERI, Hunziker 9150 (CORD) FOR, JUJ, SAL, SFE, TUC Macroptilium prostratum Aerial parts: alexipharmic No biological test Leaf + stem. Daidzein-7-O-β-D- (Benth.) Urb. BAI, CHA, COR, COS, ERI, JUJ, glucopyranoside, irigenin: isoflavone; Porotillo, porotillo del campo MIS, SAL, SDE, SFE, TUC 3-hydroxy-4'-methoxy flavone, Phaseolus prostratus Benth. nicotiflorin, hyperoside: flavonol Stuckert 14457 (CORD) Mimosa debilis Humb. & Root: for infections, hernia and No biological test No data Bonpl. ex Willd. prolapse Celosita grande, celosita hoja COS, FOR, JUJ, MIS, SAL, SDE, ancha TUC

Mimosa argentinensis Burkart 217 Barboza 1685 (CORD)

218 Mimosa diplotricha C. Leaf: diuretic No biological test No data Wright ex Sauvalle Root: against amigdalitis and Tomo34(1-2):7-365.2009 Arbo 8423 (CTES) faringitis CHA, COS, FOR, MIS Mimosa pigra L. var. pigra Root + leaf : vulnerary, purgative Leaf: molluscicidal activity Dried stem bark. Triterpene Carpinchera, mata de Leaf, infusion: to treat a weak carpincho, yuquerí heart or weak pulse, febrifuge, Cocucci 3217 (CORD) antidiarrheal BAI, CHA, COS, ERI, FOR, MIS, SFE Mimosa polycarpa var. Root: for infections, hernia and No biological test No data subandina Barneby prolapse Sensitiva, celosita de hoja me- JUJ, SAL, TUC nudita, celosita chica, celosita Ahumada 8969 (SI) Mimosa rocae Lorentz & Plant: diuretic No biological test No data Niederl. BAI Zarzaparilla Cabrera 4710 (SI) Mimosa tandilensis L. Plant: diuretic No biological test No data Zarzaparilla BAI Martínez Corvetto 1786 (SI) Myrocarpus frondosus Bark and resin: cicatrizant, No biological test Plant essential oil. Benzyl cinnamate, Allemão disinfectant, to heal wounds, benzyl benzoate, methyl cinnamate, Incienso, cabreuva, incienso ulcers, to obviate scars, and to nerolidol, vanillin, benzoic acid, blanco, incienso amarillo, control respiratory and urinary farnesol, derivatives of benzoic acid incienso negro infections and cinnamic acid Zuloaga 6431 (SI) COS, MIS. Myroxylon peruiferum L. f. Dried bark: to treat urinary and Dried bark: antibacterial Dried trunk wood. Cabreuvin: Quina, quina quina, palo respiratory tract infections, activity isoflavone; nerolidol: sesquiterpene KURTZIANA trébol, incienso colorado, antidiarrheal, for hernia and prolapse, quina del campo, kina neonatal and paediatrics care, used in morada pregnancy and facilitate birth Tolaba 2155 (CORD) Resin: anticatarrhal JUJ, SAL

BARBOZA, G.E.etal.MedicinalfloraofArgentina Otholobium higuerilla (Gi- Leaf: digestive, vulnerary Aerial parts: antioxidant No data llies ex Hook.) J. W. Grimes COR, JUJ, SAL, TUC activity Higuerilla Psoralea higuerilla Gillies ex Hook. Cantero et al. s.n. (RIOC 544) Parapiptadenia rigida Cortex: anti-inflammatory, to Bark: antibacterial activity No data (Benth.) Brenan wash ulcers Anchico colorado, anchico, angi- Leaf + bark: astringent co colorado, angico, curupay-rá COS, FOR, MIS Morrone 657 (SI) Parkinsonia aculeata L. Aerial parts: febrifuge, Aerial parts: hypothermic Dried aerial parts. β-amyrin: Cina-cina, retamo rojo, diaphoretic, antirheumatic, activity, barbiturate potentiation; triterpene garabato emmenagogue, abortifacient, CNS depressant, Fresh aerial parts. Parkintin: Hunziker 9362 (CORD) antimicrobial, anti-inflammatory sympathomimetic and antiyeast flavanone Leaf, infusion: abortifacient activity Dried leaf. Apigenin, orientin: flavones Dried flowers, infusion: antipyretic, Dried seed: hemagglutinin Flower + leaf + stem. Alkaloids diaphoretic, abortifacient. activity Seed. Azetidine-2-carboxylic acid: Part not specified, infusion: aminoacid febrifuge, epilepsy, diaphoretic BAI, CAT, CHA, COS, ERI, FOR, LPA, SAL, SDE, SFE Phaseolus vulgaris var. Seed: fractures No biological test Dried leaf + stem. Cacticin, garbanzol aborigineus (Burkart) Baudet CAT, COR, JUJ, SAL, SLU, TUC nicotiflorin: flavonol Poroto, poroto común Fortunato 3518 (BAB) Poiretia tetraphylla (Poir.) Leaf: antiphlogistic, stomachic, No biological test Aerial parts. Tannins, flavonoids, Burkart tonic, antihelminthic, vulnerary, saponins Té del campo, té pampa diaphoretic Leaf essential oil. E-Nerolidol, β- Hunziker 23569 (CORD) BAI, CHA, COR, COS, ERI, LPA, caryophyllene, germacrene D, SDE, SFE, TUC limonene, β-pinene, trans-β-ocimene Prosopis affinis Spreng. Root: contraceptive No biological test No data Ñandubay, ñandubey, espinillo, Bark: detergent, astringent algarrobillo, ibopé-morotí, BAI, CHA, COR, COS, ERI, FOR, 219 algarrobo ñandubay, piguiñik SDE, SFE Hunziker 3380 (CORD)

Prosopis alba Griseb. var. Root: antilithic, stomachic Dried fruit: ˜ -glucuronidase Leaf. β-phenethylamine: isoquinoline 220 alba Leaf: for stomach-ache inhibition alkaloid; tyramine, tryptamine, 2-β- Tomo34(1-2):7-365.2009 Algarrobo blanco, algarrobo Fruit: anti-asthmatic, astringent, methyl-3-β-hidroxy-6-β- colorado, árbol blanco, ibopé, abluent, ophtalmic piperidinedodecanol: alkaloids; malumpe, maapik, igopé- Fruit + leaf: astringent, antilithic, tonic quercetin: flavonol pará. BAI, CHA, COR, COS, ERI, FOR, Bark. Tannins Hunziker 13814 (CORD) JUJ, SAL, SDE, SFE, SLU Prosopis alpataco Phil. var. Fruit: anti-inflammatory Dried aerial parts: radical Aerial parts. Phenethylamine, alpataco fo. alpataco BAI, CHU, LPA, LRI, MEN, scavenging effect; DNA binding tryptamine: alkaloids Alpataco NEU, RNE, SJU effect Dried bark. tetrahydro harman: indole Roig 3004 (MERL) alkaloid; cassine, N-methyl cassine, eleagnine Leaf. Rutin: flavonol Seed. β-sitosterol: sterol Prosopis caldenia Burkart Bark: astringent No biological test Entire plant. Vitexin: flavone Caldén, tusca, guitrú, witrú BAI, COR, LPA, MEN, RNE, Leaf. Pipecolic acid,4-hydroxyproline, Hunziker 9369 (CORD) SLU proline: proteid

Prosopis chilensis (Molina) Fruit: astringent, stomachic, for Fresh entire plant: antibacterial Entire plant. Luteolin, vitexin, Stuntz emend. Burkart var. pharyngitis, anti-inflammatory activity isovitexin, rutin, quercetrin-3-methyl chilensis Unripe-fresh fruit: astringent, Dried aerial parts: glucosidase ether; phenethylamine, tryptamine: Algarrobo, algarrobo blanco, galactagogue inhibition; DNA binding effect alkaloids algarrobo panta, panta, árbol Seed: diuretic Seed: antibacterial activity Leaf. Pipecolic acid: proteid blanco, huelte, capesi CAT, COR, LRI, MEN, SAL, Dried seed. Protein; dopa Sayago 2624 (CORD) SDE, SJU, SLU, TUC Prosopis ferox Griseb. Flowers: antirheumatic No biological test Leaf. Pipecolic acid, proline: proteids Quiscataco, churqui jujeño, JUJ, SAL cholonea, algarrobilla Krapovickas 1521 (CORD)

Prosopis flexuosa DC. var. Leaf: ophtalmic Dried aerial parts: glucosidase Entire plant. Juliprosine, KURTZIANA flexuosa f. flexuosa Fruit: astringent, anticatarrhal inhibition; DNA binding effect; phenethylamine, 2-β-methyl-3-β- Algarrobo, algarrobo dulce, BAI, CAT, COR, LPA, LRI, free radical scavenging activity hydroxy-6-β-piperidinedodecanol, algarrobo negro, algarrobo ama- MEN, RNE, SAL, SJU, SLU, TUC juliprosopine, juliprosine: alkaloids; rillo, lámar, monte criollo, patay luteolin-7-glucoside, isorhamnetin-3- Roig 5396 (SI) rutinoside; catechin Leaf. Pipecolic acid: proteid

Prosopis kuntzei Harms Root: astringent Aerial parts: bactericidal Dried entire plant. Rutin, vitexin, BARBOZA, G.E.etal.MedicinalfloraofArgentina Itín, palo mataco, carandá Bark: laxative activity isovitexin negro, barba de tigre, kiré Fruit: odontalgic Heart wood: 3,4- bos, bun Fruit + seed: cholalogue, laxative dimethoxydalbergione: benzoquinone Hunziker 12052 (CORD) CHA, COR, COS, ERI, FOR, LRI, Leaf. Pipecolic acid: proteid SAL, SDE, SFE Prosopis nigra (Griseb.) Root: for infections No biological test Bark. Cassine, N-methyl cassine: Hieron. var. nigra Bark: hypocholesteremic alkaloids Algarrobo negro, algarrobo Fruit: ophtalmic, antivenereal, Leaf. Cacticin, naroside: flavonol; chico, igopé guazú, ibope-hú, digestive, eupeptic pipecolic acid: proteid; tryptamine, N- mapik, nabisé, oik, paatáik BAI, CAT, CHA, COR, COS, ERI, acetyl-tryptamine, tyramine, harman: Cantero s.n. (RIOC 2233) FOR, JUJ, LRI, SAL, SDE, SFE, alkaloids SJU, SLU, TUC Prosopis reptans Benth. Leaf: ophtalmic No biological test Dried entire plant. Cynaroside, Mastuerzo, retortuño COR, LRI, RNE, SDE, SFE, SJU, petunidin: flavone Hunziker 6122 (CORD) TUC Prosopis ruscifolia Griseb. Bark: astringent, antimicrobial Dried leaf: antibacterial activity Dried bark. Cassine, N-methyl cassine, Vinal, visnal, viñal, mata Leaf: antiophtalmic, hepatic, vinaline, eleagnine: alkaloids; pipecolic paso, ibope-morotí, ñiraso, stomach-ache; decoction: for sore acid: proteid; vitexin crasék eyes Ragonese 76 (SI) Leaf + twigs, infusion: abortifacient CHA, COR, FOR, SAL, SDE, SFE, TUC Prosopis sericantha Gillies Pith, decoction: diuretic No biological test Dried bark. Cassine, N-methyl cassine, ex Hook & Arn. CAT, CHA, COR, FOR, LRI, eleagnine Temoj, ba rba de t igre, al garro- MEN, SAL, SDE, SJU, SLU, TUC Leaf. Luteolin: flavone; pipecolic acid: billa, h uaschilla, retam a, esp ina proteid de Dios, albardón, matorra Ruiz Leal 9575 (SI) Prosopis strombulifera Dried bark, decoction: to treat Dried fruit: antibacterial Aerial part. Luteolin, luteolin-7- (Lam.) Benth. var. urinary and respiratory tract activity glucoside, quercitrin, rhamnosylvitexin strombulifera infections, antidiarrheal Dried stem pith. Cynaroside, luteolin: Retortuño, retortina, Fruit: antidiarrheal, astringent, flavone mastuerzo, pata de loro, anti-inflammatory, odontalgic secatrapo, espinilla BAI, CAT, COR, JUJ, LPA, LRI, 21 Cantero et al. s.n. (RIOC MEN, NEU, RNE, SAL, SJU, 3191) SLU, TUC

222 Prosopis vinalillo Stuck. Leaf: hepatic disorders No biological test Dried entire plant. Luteolin, vitexin: Vinalillo, algarrobo CHA, COR, FOR, SAL, SDE, flavone Tomo34(1-2):7-365.2009 santiagueño, quilin TUC Dried bark. N-methyl cassine: alkaloid Sayago 2898 (SI) Pterogyne nitens Tul. Stem bark: vermifuge Aerial parts: antifungal activity Aerial parts. Kaempferol, , Viraró, tipa, tipa colorada, CHA, COS, ERI, FOR, JUJ, MIS, Leaf: antimalarial activity kaempferitrin, pteroginoside, quercetin, tipilla, palo mortero, bálsamo SAL, TUC Leaf + fruit: cytotoxic and isoquercitrin, rutin, quercetin 3-O- Martínez 157 (CORD) antioxidant activity; soforoside, sorbifolin, sorbifolin 3-O- myeloperoxidase inhibitory glycoside, pedalin, pedalitin, activity nitensoside A, B: flavonoids Dried leaf. Apigenin, pedalin: flavone; guanidine alkaloids; flavonoids Leaf + fruit. Flavonols; pterogynoside-A (3”-O-4”’-methylgalloyl-afzelin), pterogynoside-B (6”-O-rhamnosyl-3’- deoxypedaliin), and other flavones Fruit. Pterogynoside: kaempferol derivative; kaempferol, afzelin, kaempferitrin, quercetin, isoquercetrin, rutin: flavonols Rhynchosia diversifolia Leaf: hepatic, drastic, purgative, No biological test No data Micheli var. diversifolia emollient Porotillo, sanalotodo CHA, COR, COS, ERI, FOR, JUJ, Hunziker 9418 (CORD) MIS, SAL, SFE, TUC Rhynchosia senna Gillies ex Leaf : digestive, hepatic, Aerial parts: antibacterial Dried entire plant. Phenolic glycosides Hook. var. senna purgative, emollient activity Porotillo, sen del campo, sen Dried entire plant: medicinal del zorro BAI, CHA, COR, COS, ERI, JUJ, Hunziker 6184 (CORD) LPA, MIS, SAL, SDE, SFE, SLU,

TUC KURTZIANA Senna aphylla (Cav.) H. S. Aerial part: antiseptic Aerial parts: antibacterial No data Irwin & Barneby Leaf: laxative, cathartic, emollient activity Pichanilla, pichana BAI, CAT, CHU, COR, LPA, LRI, Hunziker 6220 (CORD) MEN, NEU, RNE, SAL, SDE, SJU, SLU, TUC

Senna arnottiana (Gillies ex Part not specified: emetic, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Hook.) H. S. Irwin & Barneby emollient, drastic Sen, tara MEN, NEU, RNE Barboza 1229 (CORD) Senna birostris var. Leaf: emollient No biological test Part not specified. Sucrose: hookeriana (Hook.) H. S. Seed: laxative, emetic carbohydrate; physcion: quinoid Irwin & Barneby CAT, COR, LRI, SJU, SLU, TUC (sub nom. S. birostris) Acacio del campo, tabaquillo, chosno, chosmo, tacayo, café del campo Bernardello 400 (CORD) Senna chloroclada (Harms) Leaf: for skin eruptions No biological test No data H. S. Irwin & Barneby CHA, FOR, SAL, SFE Fortunato 1398 (BAB) Senna corymbosa (Lam.) Root: abortifacient No biological test Dried aerial parts. 4-hydroxy H.S. Irwin & Barneby Leaf: emollient, analgesic, laxative benzaldehyde: benzenoid; linoleic acid: Caña fí stula, s en del cam po, Leaf, fruit, seed: purgative, lipid; β-sitosterol: sterol rama negra, sen drastic, to relieve the pruritis Hunziker 11960 (CORD) BAI, COR, COS, ERI, LPA, MIS, SFE, TUC Senna crassiramea (Benth.) Aerial part: for infections No biological test No data H.S. Irwin & Barneby Flowers: kidney disorders Sumalagua CAT, JUJ, SAL, TUC Cocucci 2644 (CORD) Senna hirsuta var. puberula Leaf: skin itching No biological test Dried aerial parts. Stigmasterol: sterol H. S. Irwin & Barneby CHA, FOR, JUJ, SAL, SDE, TUC Pito canuto Biganzoli et al. 1630 (SI) Senna kurtzii (Harms) H. S . Part not specified: drastic, No biological test No data Irwin & Barn. emollient Cacho carnero MEN, NEU Fortunato 4314 (BAB) Senna morongii (Briton) Aerial parts: detergent, No biological test No data H.S.Irwin & Barneby disinfectant, hepatic, cicatrizant, Sen, pito canuto, algarrobo de antilithic; decoction: antiseptic los caranchos, sen del burro, Leaf, fruit + seed: purgative, pito, sen del burro, sen del drastic, emollient 223 campo, mala taco CHA, COR, COS, ERI, FOR, JUJ, Hunziker 11014 (CORD) SAL, SDE, SFE, SLU

Senna occidentalis (L.) Link Plant: resolutive, astringent, tonic, Leaf: anti-pyretic, anti-inflam- Entire plant. Anthraquinones, aloe- 224

Café de Bonpland, café del anthelmintic, antispamodic, matory, analgesic, antimutagenic, emodin Tomo34(1-2):7-365.2009 monte, café cimarrón, febrifuge, purgative, and anti-platelet aggregation Leaf. Apigenin and others flavonoids taperibá, fedegoso emmenagogue, for headache, cold, activity; protective effect Cassia occidentalis L. anaemia and spleen diseases Root bark: antimalarial activity Martínez 302 (CORD) COS, ERI, FOR, JUJ, MIS, SAL, (sub nom. C. occidentalis) SDE, TUC Aerial parts + seeds: antimicrobial activity (sub nom. C. occidentalis) Senna pendula var. Leaf: purgative No biological test No data eriocarpa (Griseb.) H. S. JUJ, SAL, TUC Irwin & Barneby Nicora 8747 (SI) Senna pendula var. paludi- Aerial parts: hepatic disorders No biological test No data cola H. S. Irwin & Barneby COS, ERI, FOR, MIS, SFE Pitacanuto de agua Morrone 4456 (SI) Senna spectabilis (DC.) H. Leaf: emollient, purgative; for skin Leaf + flowers: antimicrobial Flowers. (-)-spectaline; (−)-3-O-acetyl- S. Irwin & Barneby diseases activity spectaline, (2R,3R,6S)-2-Methyl-6-(13- Carnaval, caña fístula macho BAI, JUJ, SAL, SFE Flowers + fruit: DNA- oxotetradecyl)piperidin-3-yl acetate; Morrone 4605 (SI) damaging activity 13-[(2S,5R,6R)-5-hydroxy-6- methylpiperidin-2-yl]tetradecan-2-one (6), (-)-7-hydroxyspectaline, iso-6- spectaline: piperidine alkaloids Green fruit. (-)-3-O-acetylspectaline, (- )-7-hydroxyspectaline, iso-6-spectaline, (-)-spectaline: pyridine alkaloids Senna subulata (Griseb.) H . Leaf: cathartic No biological test No data S. Irwin & Barneby CAT, COR, JUJ, LRI, SAL, SLU,

Caro 3519 (CORD) TUC KURTZIANA Sesbania punicea (Cav.) Bark: astringent Part not specified: cytotoxic Mature seed. Canavanine: aminoacid Benth. Dried leaf, infusion: antiseptic, activity Acacia mansa, acacia negra astringent Seed: antitumor activity Cocucci 2989 (CORD) Dried root, infusion: antidiarrheal BAI, COS, COR, ERI, MIS, SFE, TUC

Sophora linearifolia Griseb. Leaf: cardiotonic No biological test Dried entire plant. Anagyrine, BARBOZA, G.E.etal.MedicinalfloraofArgentina Hunziker 9963 (CORD) COR, SLU baptifoline: quinolizidine alkaloid; sparteine: quinolizidine alkaloid Tephrosia cinerea (L.) Pers. Dried entire plant, infusion: to Leaf essential oil: larvicidal Leaf essential oil. Caryophyllene oxide Añil bravo treat CNS diseases property Cocucci 2951 (CORD) Root: analgesic, anti-inflammatory Root: cytotoxic activity and for scabies BAI, CHA, COS, ERI, MIS, SFE, TUC Tipuana tipu (Benth.) Kuntze Resin: cicatrizant, uterine anti- Fresh leaf + stem: antiphage Dried flowers. Amyrin, lupenone: Tipa blanca inflammatory activity triterpene Tolaba 630 (CORD) ERI, JUJ, SAL, TUC Trifolium polymorphum Entire plant: antitussive No biological test No data Poiret var. polymorphum BAI, CHA, COR, COS, ERI, LPA, Trébol del campo, trébol MIS, RNE, SFE maní, trébol criollo Hunziker 12782 (CORD) Vigna adenantha (G. Mey.) Leaf: emetic No biological test Leaf + stem. Flavonoids Maréchal, Mascherpa & BAI, CHA, COS, ERI, FOR, JUJ, Stainier MIS, SAL, SFE Pedersen 12307 (SI) Zuccagnia punctata Cav. Dried entire plant: vulnerary Dried aerial parts: antiulcer, Dried entire plant. 2’,4’-dihydroxy-3’- Jarilla macho, jarilla de la Leaf + stem: antirheumatic, antioxidant, cytoprotective, methoxychalcone, 2’,4’- puna, laca, pus-pus diuretic, antispamodic, cathartic, antibacterial, and antifungal dihydroxychalcone: chalcones; Ariza Espinar 1998 (CORD) antiseptic, rubefacient, anti- activity flavone,3-7-dihydroxy: flavonol inflammatory CAT, LRI, MEN, SAL, SJU, SLU, TUC GENTIANACEAE Centaurium cachanlahuen Aerial parts: febrifuge, Stem, leaf + flower: anti- Aerial parts. Swertiaperenine, (Molina) B. L. Rob. depurative, tonic, hypotensive, hypertensive activity swerchirine, decusatine, 1,8-dihidroxy- Canchalagua, cachaulagua, aperitive, sudorific, analgesic, 2,3,4,6-tetramethoxy-9H-xanthone; cachanlagua, cachanlahue emmenagogue, for colds, mountain oleanolic acid; sweroside. Martínez Crovetto 3232 (SI) sickness, analgesic, anti- 225 inflammatory CHU, NEU, RNE

226 Gentianella imberbis Entire plant: hepatic, digestive No biological test No data (Griseb.) Filippa & Barboza tonic Tomo34(1-2):7-365.2009 Pasto amargo, pasto blanco CAT Hunziker 19112 (CORD) Gentianella magellanica Entire plant: for colds and No biological test No data (Gaudich.) Fabris ex D. M. influenza Moore CHU, MEN, NEU, RNE, SCR, Canchalagua TDF Wedermann 283 (CORD) Gentianella multicaulis Aerial plant: stomachic; infusion: Dried aerial parts: anti- Dried aerial parts. Oleanolic acid, (Gillies ex Griseb.) Fabris bitter tonic to stimulate the inflammatory activity; cytotoxic ursolic acid: triterpene; mangiferin, Agenciana, genciana, nencia, appetite, cardiotonic effect demethylbellidifolin-8- pasto blanco, pasto amargo, Root: digestive, febrifuge Flower + fruit + leaf: glucosildemethylbellidifolin; helilla. Flower: bitter tonic, muscular anticrustacean activity demethylbellidifolin, bellidifolin, Gentianella achalensis tonic, digestive, aperitive, hepatic isobellidifolin, swerchirin: xanthones; (Hieron. ex Gilg.) T. N. Ho & Part not specified: hepatic, sweroside, gentiopicroside: S. W. Liu cardioactive secoiridoids; swertisin: flavonoid. Filippa 40 (CORD) COR, LRI, MEN, SJU, SLU Gentianella pa rviflora (Gri- Aerial parts: bitter tonic, Aerial parts: anti-inflammatory Dried aerial parts. Oleanolic acid, seb.) T. N. Ho febrifuge, hepatic, nervine activity ursolic acid: triterpene; mangiferin, Nencia, agenciana, genciana, Dried root, decoction: to treat demethylbellidifolin-8- pasto blanco, pasto amargo respiratory and urinary tract infections glucosildemethylbellidifolin; Filippa 42 (CORD) COR demethylbellidifolin, bellidifolin, isobellidifolin, swerchirin: xanthones; sweroside, gentiopicroside: secoiridoids; swertisin: flavonoid GERANIACEAE Geranium albicans A. St.-Hil. Leaf: astringent, hemostatic, No biological test Dried aerial parts. , Alfilerillo hypotensive , quercetin, rhamnazin:

Ariza Espinar 1686 (CORD) BAI, COR, ERI, LPA, RNE, SFE flavonols KURTZIANA Geranium berteroanum Colla Part not specified: dermatologic, No biological test No data Alfilerillo, corecol hepatic-intestinal Geranium chilense Ae do & BAI, CHU, MEN, NEU, RNE, Muñoz Garm. SCR, TDF Chiapella 1747 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Geranium core-core Steud. Entire plant: astringent, diuretic, Aerial parts: hypoglycaemic No data Core-core ophtalmic activity Bernardello 401 (CORD) BAI, CHU, COR, LPA, MEN, NEU, RNE, SCR, SJU, SLU, TDF Geranium magellanicum Leaf: astringent No biological test No data Hook. f. CHU, NEU, RNE, SCR, TDF Barboza 31 (CORD) Geranium sessiliflorum Whole plant: for diabetes, kidneys, Aerial parts: antibacterial No data Cav. liver, and urinary problems, activity Kiesling 7348 (SI) inflammation of all kinds Root: to treat uterine cancer CAT, CHU, JUJ, LRI, MEN, NEU, RNE, SAL, SCR, SJU, SLU, TDF, TUC GESNERIACEAE Mitraria coccinea Cav. Leaf + bark: refrigerant, laxative No biological test Aerial parts. Mitrarioside A1 ((6S)-19-(β- Botellita, voqui-voqui CHU, NEU, RNE D-galactopyranosyloxy)-6-hydroxy-15-(α- Chiapella 1776 (CORD) Lrhamno-pyranosyloxy)labda-8(17),13- diene); mitrarioside A2 ((6S)-19-(β-D- glucopyranosyloxy)-6-hydroxy-15-(α-L- rhamnopyranosyloxy)labda-8(17),13- diene); mitrarioside B ((6S)-19-(β-D- glucopyranosyloxy)-6-hydroxy-15-(β-D- glucopyranosyloxy)-labda-8(17),13-diene); mitrarioside C ((6S)-19-(β-D- glucopyranosyloxy)-6,15-dihydroxylabda- 8(17), 13-diene); mitrarioside D ((6S)-19- (α-L-rhamnopyranosyloxy)-6,15- dihydroxy-labda-8(17),13-diene); acteoside, calceolarioside C Sinningia tubiflora (Hook.) Underground stem: laxative No biological test No data Fritsch. CHA, COR, COS, ERI, FOR, Trompetilla, cisa-puca, flor SDE, SFE de San Juan, nardo del monte, samba maría 227 Hunziker 10670 (CORD)

228

GUNNERACEAE Tomo34(1-2):7-365.2009 Gunnera apiculata Schindl. Leaf: against hepatic and No biological test No data Cabrera 20620 (LP) gastrointestinal afeccions. Part not specified, infusion: febrifuge for intestinal fevers and biliousness. JUJ, SAL Gunnera schindleri L. E. Fruits: narcotic No biological test No data Mora JUJ Castillón 384 (LIL) Gunnera tinctoria (Molina) Leaf: astringent, depurative, Dried aerial parts: xanthine Dried entire plant. Daucosterol: Mirb. antidiarrheal, for backache. oxidase inhibition steroid; erythrodiol, uvaol: triterpene; Nalca Part not specified: antitussive, Entire plant: anti-thrombotic loliolide: sesquiterpene Fortunato 5233 (BAB) urinary, circulatory effect CHU, NEU, RNE GROSSULARIACEAE Ribes cucullatum Hook. & Part not specified: medicinal No biological test No data Arn. CHU, MEN, NEU, RNE, SCR, Fortunato 4930 (BAB) TDF Ribes magellanicum Poir. Aerial parts: analgesic- anti- No biological test No data Subsp. magellanicum inflammatory/circulatory Zarzaparrilla, parrilla, parrilla Leaf: antisiphilitic negra Root: diuretic, diaphoretic Boelcke 15228 (BAB) RNE, SCR, TDF Ribes punctatum Ruiz & Leaf: astringent, refrigerant No biological test No data Pav. MEN, RNE Boelcke 3641 (BAB) Ribes valdivianum Phil. Part not specified: medicinal No biological test No data KURTZIANA Fortunato 5741 (BAB) NEU

HYDNORACEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina Prosopanche americana Root: antiseptic, cicatrizant Aerial parts: antibacterial No data (R.Br.) Baill. Dried rhizome, infusion: activity Flor de tierra, hongo, guay- antiasthmatic Dried flowers: antiyeast activity curú, huáchar, guachar, flor Flowers, fruit and stem: anti- de fierro, espinazo de lagarto asthmatic, expectorant, alexipharmic, Hunziker 11000 (CORD) hemostatic, cicatrizant Flowers, decoction: for sore throat, hemostatic, expectorant BAI, CAT, COR, LPA, LRI, MEN, SAL, SDE, SJU, SLU, TUC Prosopanche bonacinae Speg. Flowers: hemostatic, cicatrizant No biological test No data Flor de tierra, hongo, guaycurú, BAI, CAT, COR, LPA, MEN, papa del monte, poñi, ancañoca MIS, NEU, RNE, SDE, SLU, TUC Hunziker 10955 (CORD) HYDRANGEACEAE Hydrangea serratifolia Bark + leaf: astringent, febrifuge No biological test No data (Hook. & Arn.) F. Phil. CHU, RNE Boelcke 5974 (BAB) HYDROLEACEAE Hydrolea spinosa var. Root: contraceptive Dried aerial parts: No data paraguayensis (Chodat) COS, FOR, MIS molluscicidal activity Davenp. Barboza 1667 (CORD) HYDROPHYLLACEAE Nama undulatum Kunth var. Leaf: insecticide No biological test No data undulatum CAT, COR, LRI, MEN, SAL, Mata gusano, yerba del zorro SDE, SJU, SLU, TUC Hunziker 12832 (CORD) HYPERICACEAE Hypericum brasiliense Plant: cardioactive, stimulant, Aerial parts: antidepressant Aerial parts. Hyperine, isoquercetrin, Choisy antispasmodic and antiofidic agent activity; general depressant quercertin, kaempferol: flavonoids Guaglianone 2867 (SI) BAI, CHA, COS, DFE, ERI, FOR, action on the CNS Leaf + flowers. Xanthones and MIS, TUC phloroglucinol derivatives Root + aerial parts. 1,5- dihydroxyxanthone, isouliginosin B,

betulinic acid, rutin, quercetin 229 Root. Acyl-phloroglucinol Aerial parts essential oil. β- caryophyllene, caryophyllene oxide

230 Hypericum carinatum Leaf: cardiotonic, antitussive, Dried aerial parts: Dried aerial parts. Chlorogenic acid: Griseb. vulnerary antibacterial, antifungal, and phenylpropanoid; quercitrin: flavonol Tomo34(1-2):7-365.2009 Bacigalupo 1528 (SI) BAI, COR, COS, ERI, FOR, MIS, carcinostatic activity SAL Hypericum connatum Lam. Aerial parts: for circulatory and Dried aerial parts: antibacterial, Dried aerial parts. Chlorogenic acid: Cabo toril, cabo torí, cardiovascular diseases, sedative antifungal, antiviral, carcinostatic phenylpropanoid; quercitrin: flavonol; sombrerito, caá-vorotí, yerba Flowers: astringent, vulnerary, and cardiotonic activity; antiprolif- hyperbrasilol B: phloroglucinol de la soledad, yerba alegre, tonic, astringent, cordial erative activity against HT-29 hu- derivative; amentoflavone, hyperoside, yerba del toro, corazoncillo BAI, CHA, COR, COS, ERI, FOR, man colon carcinoma cells and H- guaijaverine, luteoforol: flavonoids; Hunziker 9757 (CORD) JUJ, MIS, SAL, SFE, SLU, TUC 460 non-small cell lung carcinoma benzopyrans Entire plant. Tannins, flavonoids, saponins, alkaloids, anthraquinones, carditonic heterosides Hypericum silenoides Juss. Leaf: cardiotonic, antitussive, No biological test No data Cabo toril vulnerary Hunziker 7287 (CORD) COR, JUJ, SAL, TUC JUGLANDACEAE Juglans australis Griseb. Aerial parts: antiseptic, for Stem + leaf: antiviral activity No data Nogal cimarrón, nogal del país, eczema, rash and herpes nogal salteño, nogal silvestre, CAT, JUJ, SAL, TUC nogal tucumano, nogal criollo Aquino 218 (CORD) KRAMERIACEAE Krameria lappacea Aerial parts: to induce abortion, Root: cytotoxic activity against Root. Saponins, triterpenoids, (Dombey) Burdet & B. B. contraceptive breast, lung and CNS cancer flavonoids, tannins, alkaloids, quinones Simpson Leaf + stem: to cure injures , cultured cells Chipichape, chichape, iluca, antidiarrheal, diuretic, stomachic zarzaparrilla Part not specified: against Guaglianone 3138 (SI) alcoholism, diabetes, kidney and womb pain KURTZIANA CAT, JUJ, SAL, SJU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina LAMIACEAE Clinopodium bolivianum Aerial parts: antirheumatic, Aerial parts essentials oil: Aerial parts essentials oil. Pulegone, (Benth.) Kuntze digestive, vermifuge, abortive, for antiviral, antifungal, α-phellandrene, myrcene, p-cimene, E- Muña, muña-muña respiratory problems antibacterial, anti-inflammatory, caryophyllene, germacrene-D, γ- Satureja boliviana (Benth.) Leaf: neonatal and paediatrics care and cytoprotective activity cadinene, epi-α-cadinol, α-cadinol, Briq. (sub nom. S. boliviana) (sub nom. S. boliviana) spathulenol Ahumada 4271 (SI) JUJ, SAL, SLU, TUC (sub nom. S. boliviana) Aerial parts. Kaempferol 3-O- glucoside, kaempferol 3-O- xylosylglucoside, kaempferol 7-O- rhamnoside, and quercetin 3-O- sophoroside: flavonoids Clinopodium darwinii Entire plant: digestive, stomachic, No biological test Aerial parts. Essential oil (Benth.) Kuntze ulcer Satureja darwinii Benth. (sub nom. S. darwinii) Cocucci 3586 (CORD) CHU, NEU, RNE, SCR, TDF Clinopodium gilliesi Aerial parts: anti-oxidant, stomachic, Aerial parts: antimicrobial, Leaf essential oil. Pulegone; cis- (Benth.) Kuntze laxative, emmenagogue, aphrodisiac; aphrodisiac, antioxidant, dihydrocarvone, p-cimene, 1-8-cineol, Muña-muña, salvilori, muña, for hernia and prolapse, menstrual antiplasmodial, and trypanocidal E-isocitral, carvacrol, piperitenone, hillencoma, mulla-mulla, yer- diseases, used in pregnancy and activity; toxicity to the brine carvacryl acetate, piperitone oxide, ba del pájaro, hierba del amor facilitate birth, post partum pains and shrimp piperitenone oxide, menthol, lippiona, Satureja parvifolia (Phil.) diseases; against soroche (sub nom. S. parvifolia) dihydrolippiona, carvone, linalool, Epling (sub nom. S. parvifolia) isopulegol, pulegone, α- and β-pinene, Barboza 153 (CORD) CAT, COR, JUJ, LRI, MEN, SAL, limonene, sabinene, cis- SJU, TUC dihydrocarvone, menthone, neo- isomenthol (sub nom. S. parvifolia) Clinopodium odorum Leaf: stomachic, anti-oxidant, anti- Aerial parts: anticrustacean Leaf essential oil. Limonene, lippione, (Griseb.) Harley acid activity; toxicity to the brine pulegone, piperitenone oxide, linalool, Muña-muña, salviolora, (sub nom. S. odora) shrimp iso menthone, E-isocitral, E- peperina, piperina CAT, COR, JUJ, SAL, SLU, TUC (sub nom. S. odora) caryophyllene, carvacrol, Satureja odora (Griseb.) Epling bicyclogermacrene Barboza 125 (CORD) (sub nom. S. odora) 231

232 Cunila spicata Benth. Part not specified: antitussive, Aerial parts essential oil: Leaf. 3,7-dimethyl-oct-1-ene-3,6,7-triol, Rodríguez 527 (SI) pectoral, sudorific larvicidal properties linalool-O-β-D-glucopyranoside, 3,7 Tomo34(1-2):7-365.2009 COS, MIS dimethyl-octa-1,6-diene-3,8-diol-3-O-β-D- glucopyranoside, 3,7-dimethyl-octa-1,5- diene-3,7-diol-3-O-β-D-glucopyranoside, 3,7-dimethyl-octa-1,7-diene-3,6-diol-7-O- β -D-glucopyranoside, 3,7- dimethyl-oct-1- ene-3,6,7-triol-6-O-˜- D-glucopyranoside, (1S,4R,6R)-1,3,3-trimethyl-2- oxabicyclo[2.2.2]octan-6-O- β - glucopyranoside; iso-rosiridol diacetate, isomeric hydroperoxymonoterpenes, β- sitosterol, phytol, cadinol, linalool, dihydrocarveol, geranyl, neryl acetate; esters of oleuropeic acid with glucose, betulalbuside A, roseoside A Aerial parts essentials oil. Tricyclene, α-pinene, camphene, sabinene, β- pinene, mircene, limonene, 1,8-cineole, trans-sabinene hydrate, linalool, menthofuran, borneol, terminen-4-ol, bornyl acetate, β-caryophyllene, allo- aromadendrene, germacrene D, bicyclogermacrene, caryophyllene oxide; hydroperoxy diacetates Glechon ciliata Benth. Aerial parts: diaphoretic, anti- No biological test No data Krapovickas 26160 (BAB) catharral, excitant, diuretic COS, FOR, MIS Hedeoma mandonianum Aerial parts: antiparasitic; for Aerial parts essential oil: Fresh aerial parts essent oil.

Wedd. migraine, burns, and stomach insecticide activity. Aromadendrene, globulol: KURTZIANA Muña aches sesquiterpenes; camphor, piperitone, Meyer 22626 (LIL) JUJ, SAL limonene, citronellal Hedeoma medium Epling Plant: digestive No biological test No data Tomillo BAI, ERI Nicora 3272 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Hedeoma multiflorum Aerial parts: aromatic, digestive, No biological test Essential oil. Carvone, limonene, Benth. anticephalalgic pulegone, isomenthone, menthone, Tomillo del campo, tomillo Dried leaf, decoction: to treat piperitenone, α-pinene, β-pinene, serrano, menta del campo, respiratory and urinary tract myrcene, trans-β-ocimene, cis- flor del pájaro, peperina de infections isopulegone, α-copaene, (+)- las lomas BAI, COR, LPA, MEN, RNE, aromadendrene, germacrene-D, Ariza Espinar 549 (CORD) SDE, SLU bicyclogermacrene, germacrene-A Hyptis floribunda (Briq.) Flowering tops, infusion: No biological test Leaf essential oil. Germacrene A, B, D, Briq. ex Micheli abortifacient cis nerolidol, α-humulene, β- Verbena, verbena negra BAI, CHA,COR, COS, ERI, FOR, caryophyllene, δ-cadinene, β- Barboza 1532 (CORD) MIS, RNE, SAL, SFE, TUC bourbonene,γ-elemene, γ-elemene, α- copaene: sesquiterpenes; α-pinene Hyptis lappacea Benth. Part not specified: cephalalgic No biological test No data Novara 9884 (CORD) Flowers: for sore throat and dysphonia, anti-inflammatory BAI, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Hyptis mutabilis (Rich.) Dried aerial parts, plant juice: to Fresh leaf essential oil: Dried aerial parts. Aromadendrene, β- Briq. calm crying infants; insecticide or antiulcer activity bisabolene: sesquiterpenes; betulinic Verbena negra, verbena vermifuge; carminative and acid methyl ester: triterpene Hunziker 15914 (CORD) digestive Fresh aerial parts essential oil. Root: antidiarrheal contraceptive Camphor: monoterpene Leaf + flowers: digestive, stomach-ache, antirheumatic, febrifuge, against toothache, vulnerary, abortifacient, diaphoretic, carminative BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Lepechinia meyenii (Walp.) Flowers: pectoral Aerial parts essential oil: Dried aerial parts. Pisiferol, rosmanol, Epling Part not specified: digestive, antimicrobial activity carnosic acid, salvicanol, isosalvicanol, Salvia against flu 12-formyl-11-hydroxy-8,11,13- Subils 3334 (CORD) CAT, COR, JUJ, LRI, SAL, TUC abietatrien-2-oic acid methylester:

abietane diterpenoids; oleanolic acid 233

234 Lepechinia vesiculosa Aerial parts: for infections, used No biological test No data (Benth.) Epling in pregnancy and facilitate birth Tomo34(1-2):7-365.2009 Salvia grande CAT, JUJ, SAL, TUC Barboza 1763 (CORD) Minthostachys verticillata Leaf + flower: stomachic, Aerial parts essential oil: Aerial parts essential oil. Pulegone, (Griseb.) Epling antispamodic, antidiarrheal, anti- fumigant and repellent activity menthone, limonene, piperitenone, γ- Peperina, peperita, piperita emetic, antirheumatic, carminative, against head lice; anti-allergic terpinene, linalool, isomenthone, Zygadlo 234 (CORD) sedative, hemostatic, hypotensive and lymphoproliferative carvone, carvacrol, carvacryl acetate, Dried leaf + stem, infusion: carmin- properties camphene, p-cymene, myrcene, α- ative, for fertility and sexual stimulant Fresh leaf + stem: mutagenic pinene, β-pinene, sabinene, α and γ- CAT, COR, JUJ, SAL, SDE, SLU, and antiviral activity terpinene, isopulegol, δ-cadinene, β- TUC Flower + leaf: antiyeast activity caryophyllene, γ-gurjunene, τ-cadinol, thymol Leaf essential oil. β-caryophyllene: sesquiterpene; myrcene: monoterpene (E)-β-ocimene Ocimum selloi Benth. Aerial parts: carminative, Leaf essential oil: antibacterial, Aerial part. Caffeic acid derivative, Albahaca del campo, diaphoretic, sudorific, against antioxidant, analgesic and anti- flavonoid, benzoic acid derivative albahaca del campo toothache, diarrhea, intestinal diarrheal activity Aerial parts essential oil. β-bisabolene: cimarrona, albahacón spasm, and visceral pain sesquiterpene Ariza Espinar 1118 (CORD) COS, ERI, JUJ, MIS, SAL, SFE Inflorescence + leaf essential oil. 3- octenol, trans-ocimene, methyl chavicol, cis-anethol, trans-anethol, δ-elemene, α- copaene, β-bourbonene, β-cubebene, β- elemene, methyl eugenol, trans- caryophyllene, β-gurjunene, α-humulene, allo-aromadendrene, germacrene D, β- selinene, α-(E,E)-farnesene, δ-cadinene, spathulenol, α-neoclovene

Leaf . Rosamarinic acid, lithospermic KURTZIANA acid, p-coumaric acid, hydroxy-benzoic acid Peltodon longipes A. St.-Hil. Part not specified: emmenagogue No biological test No data ex Benth. COS, MIS Barboza 1485 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Salvia calolophos Epling Leaf : hepatic disorders, diuretic No biological test No data Salvia de la puna JUJ, SAL Venturi 8069 (LIL, SI) Salvia cardiophylla Benth. Leaf: digestive Dried aerial parts: insect Dried aerial parts. Cardiophyllidin: Ariza Espinar 2498 (CORD) Dried aerial parts: insecticide or repellent activity diterpene; oleanolic acid: triterpene vermifuge BAI, CAT, CHA, COS, ERI, FOR, SDE, SFE, SAL Salvia cuspidata subsp. Aerial parts: stomachic, stomach- Dried branch + leaf: Aerial parts essential oil. gilliesii (Benth.) J.R.I. Wood ache, pectoral, anticatarrhal, antibacterial and antioxidant Aromadendrene, bicyclogermacrene: Salvia, salvia morada, , salvia febrifuge, sedative, for hernia and activity sesquiterpene; limonene: monoterpene gateadora, hillencoma, prolapse, used in pregnancy and (sub nom. S. gilliesii) (sub nom. S. gilliesii) salvelapuna, salvia del facilitate birth, post partum pains campo, salvia silvestre and diseases Hunziker 14835 (CORD) Dried branch + leaf, decoction: to treat respiratory and urinary tract infections CAT, COR, JUJ, LPA, LRI, MEN, SAL, SJU, SLU, TUC Salvia meyeri Legname Aerial parts: against cold No biological test No data Cocucci 2611 (CORD) diseases, hepatic affections, migraine and nausea caused by non-adjustemente to altitudes, for cold and cough, influenza, dyspepsia, diarrhea, gastrointestinal bloating, to avoid vomiting, stomach ache. JUJ, SAL Salvia pallida Benth. Part not specified: antirheumatic, No biological test No data Fortunato 2801 (BAB) for cramps BAI, CHA, COR, COS, DFE, ERI, FOR, LPA, MIS, SFE Salvia procurrens Benth. Part not specified: antitussive, No biological test No data

Cocucci 2960 (CORD) tonic, antiscorbutic 235 BAI, DFE, ERI

Salvia stachydifolia Benth. Part not specified: vulnerary No biological test No data 236

Venturi 4956 (BAB) CAT, JUJ, SAL, TUC Tomo34(1-2):7-365.2009 Stachys gilliesii Benth. Aerial plant: to relieve the No biological test No data Ortiga mansa pruritis, aphrodisiac, tonic Hunziker 6317 (CORD) CHA, COR, COS, FOR, JUJ, MEN, TUC Teucrium cubense subsp. Leaf: hypocholesteremic, stomachic ; Dried leaf + stem: Aerial parts. Eugarzasadine, teucvin: cordobense Epling decoction: abortifacient hypoglycemic activity diterpenes Seidedos Dried leaf + stem, decoction: Hunziker 11148 (CORD) hypoglycemic CAT, COR, COS, MEN, SAL, SDE, SFE, SLU, TUC Vitex cymosa Bertero ex The whole plant: scabies, skin No biological test Aerial parts. Aucubin: iridoid Spreng. itching glucoside Taruma, tacurumá Bark: against diarrhea Aerial parts essential oil. β- Biganzoli 1323 (SI) FOR, MIS himachelele, E-E-α-farnesene, β- bisabolene, α-dehydro-ar-himachelele, Z-γ-bisabolene, β-vetivenene, himachelele oxide, spathulenol, caryophyllene oxide, β-copaen-4-α-ol, carotol, β-himachelele oxide, cubenol, Z, Z-farnesol, phytol, isophytol Stem bark. 26-hydroxypinnatasterone, 20-hydroxyecdysone: ecdysteroids Fruit. 3,5-di-caffeoylquinic acid Vitex megapotamica Cortex: antisyphilitic, anti- Leaf: anti-hyperglycemic action Entire plant. β-ecdysone: steroid (Spreng.) Moldenke aphrodisiac Dried aerial parts. Agnuside: iridoid Krapovickas 21551 (SI) Dried leaf, decoction: against skin monoterpene disease, diuretic Fruit: emmenagogue, diuretic, anodyne COS, MIS KURTZIANA LARDIZABALACEAE Boquila trifoliolata (DC.) Plant: to cure injures and eye No biological test No data Decne. infections Pi-pil, voqui, voquicillo, CHU, NEU voquillo, voqui blanco Meyer 9298 (LIL)

BARBOZA, G.E.etal.MedicinalfloraofArgentina LAURACEAE Cinnamomum porphyrium Bark: used in pregnancy and No biological test No data (Griseb.) Kosterm. facilitate birth Laurel Leaf: severe intestinal bloating Brown 1585 (CORD) antidiarrheal, neonatal and paediatrics care CAT, JUJ, SAL, TUC Nectandra angustifolia Bark: purgative, digestive Leaf: anti-inflammatory, anti- No data (Schrad.) Nees & Mart. ex Leaf: anti-inflammatory, for the haemolityc, antiprotozoal, Nees relief of pain, arthritis, rheumatism molluscicidal, and antimicrobial Laurel mini and diarrhea, as and activity Nectandra falcifolia (Nees) J. for snakebite (sub nom. N. falcifolia) A. Castigl. ex Mart. Crov. & (sub nom. N. falcifolia) Piccinini BAI, CHA, COS, ERI, FOR, MIS, Zuloaga 5760 (SI) SFE Nectandra lanceolata Nees Part not specified: to treat asthma Leaf: antimicrobial activity Alkaloids & Mart. ex Nees FOR, MIS Laurel amarillo, laurel morotí, canela amarilla, canela blanca Guaglianone 2820 (SI) Ocotea acutifolia (Nees) Cortex: astringent Leaf: cytotoxic activity Leaf. Ocoteine N-oxide, nor- Mez BAI, COS, ERI, MIS ocoxylonine, ocoxylonine, ocoteine, O- Laurel blanco, laurel morotí, methylcassyfiline, dicentrine, nor- laurel del monte, laurel dicentrine, leucoxine, isodomesticine, criollo, laurel de las islas neolitsine: aporphinoid alkaloids Tressens 4197 (CTES) Ocotea diospyrifolia Leaf: diuretic, carminative, No biological test Heart-wood. Tannin (Meisn.) Mez emmenagogue, antirheumatic Laurel blanco CHA, COS, FOR, MIS Schinini 31770 (CTES) Ocotea lancifolia (Schott) Part not specified: vermifuge No biological test No data Mez COS, MIS

Zuloaga 5736 (SI) 237

238 Ocotea puberula (Rich.) Nees Bark: antidiarrheal, to apply as No biological test Bark. Ocoteine, thalicminine: Tomo34(1-2):7-365.2009 Laurel guaicá, l aurel bl anco, poultice to extract thorns or spines isoquinoline alkaloid laurel mestizo, guaica, guayca Part not specified: maturating Heart-wood. Tannin Cocucci 1058 (CORD) COS, JUJ, MIS, SAL Persea lingue Nees Bark: astringent No biological test Dried trunk bark. Lingueresionol: Lingue CHU lignan Zuloaga 7242 (SI) LEDOCARPACEAE Balbisia aphanifolia Part not specified: digestive, No biological test No data (Griseb.) Hunz. & Ariza carminative Té de burro, té andino CAT, LRI, SJU, SLU Hunziker 5228 (CORD) Balbisia calycina (Griseb.) Dried aerial parts, infusion: to Dried aerial parts: Dried leaf + stem. Apigenin: flavone; Hunz. & Ariza treat wounds and sores, antimicrobial, analgesic, and caffeic acid: phenylpropanoid; Té de burro, té andino, té del hepatoprotective, carminative, for antinociceptive activity scopoletin; ferulic acid país grastrointestinal disorders Dried aerial parts: Luteolin, avicularin Burkart 11734 (SI) CAT, JUJ, LRI, SAL, SLU, TUC apigenin, quercitrin, quercetin, isoquercitrin, hyperoside: flavonoids Balbisia gracilis (Meyen) Part not specified: medicinal No biological test No data Hunz. & Ariza CHU, NEU, RNE Té morado, té de la sierra Cocucci 2307 (CORD) LENTIBULARIACEAE Pinguicula chilensis Gay Leaf: antiseptic properties No biological test No data Boelcke 14301(BAB) NEU, RNE LINACEAE Clioccoca selaginoides Aerial parts: bitter tonic, No biological test No data (Lam.) C.M. Rogers & aperitive, purgative; anti-

Mildner inflammatory KURTZIANA Lino del campo BAI, COR, COS, ERI, LPA, MIS, Linum selagionides Lam. SDE Hunziker 8615 (CORD) Linum scoparium Griseb. Part not specified: digestive No biological test No data Hunziker 20123 (CORD) COR, TUC

LOASACEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina Blumenbachia dissecta (Hook. Part not specified: medicinal No biological test No data & Arn.) Weigend & J. Grau (sub nom. C. patagonica) Caiophora patagonica Urb. CHU, MEN, NEU, RNE, SCR & Gilg De Marco 258 (SI) Blumenbachia insignis Dried entire plant, infusion: No biological test Dried entire plant. 8-epi Kingiside: Schrad. rubefacient secoiridoid monoterpene; loganin Ortiga del monte Leaf and stem: antirheumatic Ariza Espinar 986 (CORD) BAI, CAT, COR, ERI, LPA, MEN, MIS, RNE, SFE, SLU Caiophora coronata (Gillies Part not specified: anticatarrhal Dried aerial parts: Dried aerial parts. Iso boonein: iridoid ex Arn.) Hook. & Arn. CAT, JUJ, LRI, MEN, SAL, SJU, antimicrobial activity monoterpene; loganin, secoxy: Ortiga de la sierra, ortiguilla, TUC secoiridoid monoterpene; 1β-, 3β- rupa chicá, ortiguilla, roseta, dihydroxyurs-12-en-27-oic acid, 1: ropá chico, ropa chico triterpene; 1α-methoxy-6α-,10- Cocucci 1337 (CORD) dihydroxyisoepiiridomyrmecin (caiophoraenin), 2, isoboonein 3: iridoids; sweroside Caiophora lateritia Klotzsch Flower: abortive, menstrual No biological test Leaf. Loganic acid Hunziker 17081 (CORD) diseases, used in pregnancy and facilitate birth CAT, JUJ, NEU, SAL, SDE, TUC LOGANIACEAE Spigelia humboldtiana Entire plant, decoction: for No biological test No data Cham. & Schltdl. snakebite, skin cleanser, to treat Barboza 383 (CORD) worms Part not specified: vermifuge BAI, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC Strychnos brasiliensis Leaf: bitter tonic, odontalgic, No biological test Aerial parts.Tabascanine, (Spreng.) Mart. stimulant, febrifuge strycnosilidine, espermostrycnine, 12- Espolón de gallo, espuela de COS, MIS hydroxy-11-methoxyspermostrycnine, gallo, palo amargo. strycnobrasiline, 12-hydroxy-11- Deginani 1064 (SI) methoxystrycnobrasiline, 10,11- dimethoxystrycnobasiline,

diacetilstrycnosilidine, 12-hydroxy-11- 239 methoxystrycnobrasiline, 10,11- dimethoxystrycnobrasiline: alkaloids

LORANTHACEAE 240

Ligaria cuneifolia (Ruiz & Entire plant: hypotensive, for Leaf + stem: antibacterial and Leaf + stem. Quercetin, epicatechin, Tomo34(1-2):7-365.2009 Pav.) Tiegh. fractures, abortifacient, antioxidant activity; effects on the quercitin-3-O-xyloside, catechin-4-β-ol, Liga roja, muérdago criollo, cardiotonic, anti-haemorrhagic, cardiovascular system and quercitin-3-O-α-arabinoside, dimers of liga, liguilla, liguilla de flor inmunomodulador cytostatic and immunomodulatory catechin-4-β-ol, quercitin-3-O-β- roja Flowers: abluent, astringent, actions; increase of blood pressure, arabinoside, oligomers of catechin-4-β- Subils 3789 (CORD) cicatrizant; nomalizes arterial variable cardiac effect; inhibition of ol, quercitin-3-O-β-rhamnoside; pressure the activated lymphoid cell growth; polymers of catechin-4-β-ol, catechin: BAI, CAT, COR, ERI, FOR, JUJ, genomic protective agents, flavonol and proanthocyanidin; LPA, LRI, MEN, SAL, SDE, SFE, carcinogenesis preventive agents cardenolides heterosides SJU, SLU, TUC Fruit. Viscine Psittacanthus cordatus Leaf: for appendicitis No biological test No data (Hoffmanns. ex Schult. f.) CHA, FOR Blume Rojas 12200 (SI) Struthanthus uruguensis Leaf + stem: stomachic, No biological test No data (Hook. & Arn.) G. Don antitussive, cephalalgic; Hierba del pajarito. hypotensive Hunziker 15789 (CORD) COR, COS, ERI, FOR, LRI, MIS, SAL, SDE Tripodanthus acutifolius Dried leaf + stem: hypoglycaemic, Dried leaf + stem: mutagenic Aerial parts. Rutin (3,3',4',5,7- (Ruiz & Pav.) Tiegh. anti-inflammatory and antibacterial activity, pentahydroxyflavone 3-β- Corpo Aerial parts: abortive, menstrual genomic protective agents, rhamnosilglucoside), iso-quercitrin Hunziker 22369 (CORD) diseases, neonatal and paediatrics carcinogenesis preventive agents (3,3',4',5,7-pentahydroxyflavone 3-β- care, used in pregnancy and Dried leaf: antimalarial activity glucoside) facilitate birth, post partum pains and diseases CAT, CHA, COS, FOR, JUJ, LRI, MIS, SAL, SDE, TUC

Tripodanthus flagellaris Leaf + stem: hypotensive, No biological test Aerial parts. Cardenolides heterosides; KURTZIANA (Cham. & Schltdl.) Tiegh. caridotonic, emmenagogue tyramine Liga blanca CAT, COR, COS, ERI, LRI, SDE, Cocucci 795 (CORD) SLU Tristerix corymbosus (L.) Part not specified: medicinal No biological test Fruit. Viscine Kuijt NEU, RNE Rentzell 14676 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Tristerix verticillatus (Ruiz Entire plant: vulnerary, caustic, No biological test No data & Pav.) Barlow & Wiens hypotensive, hypertensor Puspusa, liga de molle, arita, CAT, JUJ, LRI, MEN, SAL, SJU, liga, pega-pega TUC Fortunato 7616 (BAB) LYTHRACEAE Cuphea calophylla subsp. Fresh leaf, infusion: to treat Fresh leaf: diuretic and No data mesostemom (Koehne) hypertension or induce diuresis hypotensive activity Lourteig Part not specified: diuretic, Biganzoli 56 (SI) laxative, depurative CAT, CHA, JUJ, MIS, SAL, TUC Cuphea campylocentra Part not specified: diuretic, No biological test No data Griseb. depurative, laxative Burkart 8010 (SI) COS, ERI, FOR Cuphea carthaginensis Aerial parts: antipaludic, for Aerial part: antibacterial Aerial parts. Condensed tannins, (Jacq.) J. F. Macbr. circulatory and heart diseases activity proanthocyanidins; carthagenol: Schulz 28 (LP) CHA, COS, FOR, JUJ, MIS Leaf: angiotensin-I-convertin triterpene; quercetin-3-sulphate enzyme (ACE) inhibition activity, vasorelaxant and antioxidant activity; hypocholesterolemic effect Cuphea fructicosa Spreng. Part not specified: antipaludic. No biological test No data Hurrell 5397 (SI) BAI, COR, COS, ERI, MIS

Cuphea glutinosa Cham. & Aerial parts: antipaludic, diuretic, No biological test No data Schltdl. laxative, blood depurative, Siete sangrías, sanguinaria, abortifacient, against palpitations isipó-peré and nervous diseases, cordial, Ariza Espinar 3329 (CORD) hypotensive, cephalalgic, emmenagogue, for menopause symptons (shortness of breath) and to help stop menstruation Root: abortifacient

BAI, CHA, COR, COS, ERI, FOR, 241 LRI, MIS, SFE, SLU, TUC

242 Cuphea ingrata Cham. & Part not specified: antipaludic, No biological test No data Schltdl. cardiotonic, antisyphilitic, Tomo34(1-2):7-365.2009 Arbo 6792 (CTES) sudorific BAI, CHA, COR, COS, MIS, SFE, SLU, TUC Cuphea lysimachioides Medicinal No biological test No data Cham. & Schltdl. CHA, COS, FOR, MIS Schinini 31751 (CTES) Cuphea racemosa var. Entire plant, decoction: No biological test No data palustris Lourteig contraceptive; infusion: Meyer 3060 (LIL) emmenagogue Root, infusion: abortifacient BAI, CHA, COR, COS, ERI, FOR, MIS, SCR, SFE Heimia salicifolia (Kunth) Dried aerial parts: to treat respira- Dried aerial parts: Dried entire plant. Abresoline, 10-epi Link tory and urinary tract infections, antibacterial, antimycotic, abresoline: vertine, lyfoline, lythrine, Quiebra arado, amarillo, antisyphilitic, sudorific, antipyretic, hydrodiuretic, and anti- nesodine: quinolizidine alkaloids arupacú, araopaque, laxative, diuretic, cicatrizant, for inflammatory activity Aerial parts. Cryogenine: quinolizidine quiebra’arao, yerba de la vida bronchitis, inflammation of the Leaf: vasorelaxant effect alkaloid Subils 2287 (CORD) womb, and rhus-induced dermatitis Root: stomachic, diuretic, antidysenteric, appetitive; to help mother quickly re-establish her hips and abdomen after birth Leaf: for treating wouds externally, vulnerary Dried flowering tops, infusion: purgative, diuretic BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, LRI, MIS, SAL, SDE, KURTZIANA SFE, SJU, SLU, TUC Lythrum hyssopifolia L. Leaf + stem: aperitive, No biological test No data Stuckert 15240 (CORD) antiscorbutic, vulnerary, for haemorroids and internal bleeding BAI, COS, DFE, ERI, LPA, NEU, RNE, SFE, SJU

MALPIGHIACEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina Banisteriopsis caapi Dried bark, infusion: stimulant, to Entire plant: peroxide Vine. Harmic amide, nor harmine:, nor (Griseb.) C.V. Morton increase mental activity formation inhibition; harmine: acetyl: indole alkaloids; Ayahuasca Dried & fresh stem + leaf, monoamine oxidase inhibition shihunine, dihydro shihunine: alkaloids Legname 9690 c (LIL) infusion: hallucinogen Fresh vine: toxic effect Root. Harmine: indole alkaloid Part not specified: arrow poison (general), for nausea and Stem. Harmine, tetrahydro harmine, 6- (curare), hallucinogen vomiting, diarrhea and agitation; methoxy tryptamine,: indole alkaloids SAL antiparkinson activity Dried bark. Harmine, harmaline, Dried bark: hallucinogenic harmalol, harmol, tetrahydro harmine: activity indole alkaloids; nerolidol: Extracts: uptake stimulation sesquiterpene; stigmasterol, β-sitosterol: sterols; ursolic acid, oleanolic acid: triterpenes Leaf + stem. Harmic acid methyl ester, harmalinic acid, harmine-n-oxide: indole alkaloids Leaf. Harmine: indole alkaloid Banisteriopsis muricata Dried stem, infusion: febrifuge No biological test No data (Cav.) Cuatrec. COS, JUJ, MIS, SAL Morrone 4583 (SI) Callaeum psilophyllum (A. Medicinal No biological test No data Juss.) D. M. Johnson BAI, COS, ERI, JUJ, MIS, SAL Zuloaga 5385 (SI) Dicella nucifera Chodat Part not specified: antacid, No biological test No data Morrone 745 (SI) cardiotonic, for snakebites COS, MIS Galphimia australis Chodat Part not specified: astringent, Stem latex: proteolytic activity Stem latex. Proteins Cocucci 2959 (CORD) emetic, cathartic COS, ERI, MIS Heteropterys glabra Hook. Leaf + flowers: sedative Plant: neurophysiological No data & Arn. Fruit: sedative and anxiolytic effects Cocucci 2057 (CORD) agent CHA, COS, ERI, FOR, MIS, SFE Heteropterys intermedia Part not specified: for dizziness No biological test No data (A. Juss.) Griseb. COS, MIS 243 Morrone 1858 (SI)

244 Janusia guaranitica (A. St.- Leaf + stem: digestive No biological test No data Tomo34(1-2):7-365.2009 Hil.) A. Juss. CAT, CHA, COR, COS, ERI, Yerba de la vida FOR, JUJ, LRI, MIS, SAL, SDE, Hunziker 9230 (CORD) SFE, SLU, TUC Tricomaria usillo Hook. & Leaf + flowers: digestive, diuretic, No biological test No data Arn. diaphoretic, emmenagogue Usillo, prendedor, suri pe- CAT, COR, LRI, MEN, SJU, SLU, lado, pascana, maña-caballo TUC Hunziker 24600 (CORD) MALVACEAE Abutilon grandifolium Root + leaf: diuretic, febrifuge No biological test No data (Willd.) Sweet Leaf: capilar tonic, for pediculosis Malva, malva del monte, Cortex + flower: for stomachache malvavisco, bendición de BAI, CAT, CHA, COR, COS, ERI, Dios FOR, JUJ, LRI, MIS, SAL, SDE, Burkart 22646 (SI) SFE, SJU, SLU, TUC Abutilon herzogianum R.E. Young leaf: antidiarrheal, for No biological test No data Fr. dysentery Krapovickas et al. 47500 SAL (CTES) Abutilon pauciflorum A. Entire plant: antitussive No biological test No data St.-Hil. BAI, CHA, COR, COS, ERI, FOR, Pulmonar, malvavisco, malva JUJ, MIS, SAL, SDE, SFE, SLU, del monte TUC Di Fulvio 456 (CORD) Abutilon terminale (Cav.) Entire plant: antitussive No biological test No data A. St.-Hil. BAI, COR, COS, ERI, LPA, MIS,

Hunziker 10754 (CORD) SFE, SLU KURTZIANA Acaulimalva nubigena Root: against fever, dyspepsia, No biological test No data (Walp.) Krapov. digestive Alaituya, altea, malva CAT, JUJ, SAL, TUC Hunziker 20810 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Anoda cristata (L.) Schltdl. Fresh branches + leaf , decoction: No biological test Leaf + seed. Gossypol Malva, malva cimarrona to treat infertility; for scalp infection, Anoda cristata var. lost hair, wounds and cough brachyantha (Rchb.) Hochr. Flowers: pectoral, diaphoretic, Hunziker 11998 (CORD) vulnerary BAI, CAT, COR, ERI, JUJ, LPA, MEN, SAL, SDE, SFE, SLU, TUC Cienfuegosia drummondii Root: contraceptive No biological test Aerial parts essential oil. α-pinene: (A. Gray) Lewton Leaf and flowers: to relieve bruises, monoterpene Hunziker 11367 (CORD) emollient, antispamodic, pectoral Seed. Gossypol: sesquiterpene Part not specified: contraceptive CHA, COR, COS, ERI, FOR, SAL, SDE, SFE, TUC Cienfuegosia sulphurea (A. Leaf + flowers: to relieve bruises, No biological test Seed. Gossypol: sesquiterpene St.-Hil.) Garcke emollient, antispasmodic, pectoral Stuckert 21440 (CORD) BAI, CHA, COR, COS, ERI, SFE Gaya tarijensis R.E. Fr. Young leaf: febrifuge No biological test No data Tolaba 2676 (CORD) FOR, JUJ, SAL, TUC Hibiscus striatus Cav. Flowers: emollient No biological test No data Hunziker 3707 (CORD) BAI, CHA, COS, ERI, FOR, JUJ, MIS, SAL, TUC Krapovickasia flavescens Part not specified: emollient, No biological test No data (Cav.) Fryxell cephalalgic, diuretic Malvavisco BAI, CAT, COR, COS, ERI, FOR, Sida flavescens Cav. JUJ, LRI, MIS, SAL, SFE Chiarini 376 (CORD) Lecanophora ameghinoi Part not specified: medicinal No biological test No data (Speg.) Speg. CAT, CHU, LRI, MEN, NEU, Hunziker 13040 (CORD) RNE, SCR, SJU Malvastrum Aerial part: disifectant, anti- No biological test Seed oil. Palmitic acid, palmitoleic coromandelianum (L.) inflammatory, for circulatory and acid, stearic acid, oleic acid, linoleic Garcke subsp. cardiovascular diseases acid, malvalic acid, sterculic acid coromandelianum Root: hepatic, laxative Yerba del potro, escoba dura, Leaf: emollient potro, afata, guatana, potro BAI, CAT, CHA, COR, COS, ERI, huatana FOR, JUJ, LRI, MEN, MIS, SAL, 245 Hunziker 574 (CORD) SDE, SFE, SJU, SLU, TUC

246 Malvella leprosa (Ortega) Leaf + stem: emollient, No biological test No data Krapov. antitussive, diuretic, cephalalgic Tomo34(1-2):7-365.2009 Subils et al. 4208 (CORD) BAI, CHA, CHU, ERI, JUJ, LPA, LRI, MEN, NEU, RNE, SCR, SFE, SJU, TUC Modiola caroliniana (L.) G. Leaf + stem: emollient, Dried aerial parts: β- Leaf. Hypolaetin: flavone; kaempferol: Don refrigerant, analgesic, montain glucuronidase inhibition, flavonol Malva, mercurio, sanalotodo, sickness anticrustacean and hypotensive malvavisco, pila-pila, BAI, CHA, COR, COS, ERI, FOR, activity pelai-pelai, pela pela, malva MEN, MIS, SFE, SLU común Hunziker 12743 (CORD) Modiolastrum malvifolium Leaf + stem: anti-inflammatory; No biological test No data (Griseb.) K. Schum. against the earache Subils 3155 (CORD) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SLU, TUC Monteiroa glomerata Part not specified: diuretic, No biological test No data (Hook. & Arn.) Krapov. emollient Malva del zorro BAI, ERI Hunziker 3210 (CORD) Pavonia argentina Gürke Leaf + stem: antitussive No biological test No data Hunziker 10688 (CORD) CAT, COR, FOR, JUJ, LRI, SAL, SDE, SJU, TUC Pavonia cymbalaria A. St.- Part not specified: pectoral, No biological test No data Hil. & Naudin emollient, depurative Malvavisco BAI Grondona 2643 (SI)

Pavonia sepium A. St.-Hil. Root: for hernia and prolapse, No biological test Seed oil. Malvalic acid, sterculic acid, KURTZIANA subsp. sepium menstrual diseases, used in vernolic acid: lipids Abrojo, malvavisco del cerro, pregnancy and facilitate birth malva del monte Leaf: emollient, pectoral Hunziker 416 (CORD) BAI, CAT, CHA, COS, ERI, FOR, JUJ, MIS, SAL, SFE, TUC

Sida argentina K. Schum. Leaf: cephalalgic No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina var. argentina BAI, CAT, COR, ERI, JUJ, LRI, Hunziker 8060 (CORD) MEN, MIS, SAL, SDE, SJU, SLU, TUC Sida cordifolia L. Entire plant, decoction: Entire plant: hypotensive and Entire plant. Ephedrine: alkaloid Malva antirheumatic, aphrodisiac, antiamebic activity Root, stem, leaf. Betaine; choline: Hunziker19458 (CORD) febrifuge, for urinary diseases; Leaf: anti-inflammatory activity infusion: to treat asthma Dried root: hypoglycemic Root: against menorrhagia, laxative activity Bark, juice: to stimulate Dried seed: teratogenic activity menstruation, abortive Dried part not specified: Dried leaf, infusion: for pneumonia; antimycobacterial activity decoction: digestive, for stomachache Dried twig: chewing stick Part not specified, infusion: to improve male sexual function BAI, CAT, CHA, COS, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, TUC Sida poeppigiana (K. Part not specified: medicinal No biological test No data Schum.) Fryxell. COR, JUJ, LRI, MIS, SAL, TUC Afata Ahumada 8384 (SI) Sida rhombifolia L. Dried entire plant, infusion: Aerial parts: antibacterial and Dried aerial parts. Betaine, arginine; Afata, mata-alfalfa, escoba febrifuge and for urinary, circulatory antiarthritic activity campesterol sterol; 20- dura, yerba del potro and caridiovascular diseases; Dried entire plant: uterine hydroxyecdysone, ecdysone, 20- Hunziker 12402 (CORD) aphrodisiac, neonatal and paediatrics stimulant effect hydroxyecdysone, 2-deoxy-20- care, in treatment of rheumatism Leaf: cytotoxicity, antibacterial hydroxyecdysone-3-O-β-D- Root: hepatic, to relieve the antinociceptive and glucopyranoside, 20-hydroxyecdysone- stomachache, cephalalgic inflammatory activity. 3-O-β-D-glucopyranoside: ecdysteroids Leaf + stem: emollient, Leaf. Steroids and/or triterpenoids and refrigerant, disinfectant, febrifuge, their glycosides, flavonoids and their antitussive, cicatrizant, maturating, glycosides anti-inflammatory Leaf, infusion: for painful menstru- ation; decoction: febrifuge, for aches, cough, infections, and diarrhea

Seed: diuretic, aperitive 247 BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, MIS, SAL, SDE, SFE, SJU, SLU, TUC

Sida santaremensis Young leaf: fever No biological test No data 248 Monteiro CHA, COS, FOR, JUJ, MIS, SAL Tressens et al. 6606 (CTES) Tomo34(1-2):7-365.2009 Sida spinosa L. Aerial plant: emollient, Entire plant: hypoglycemic Dried aerial parts. Ephedrine: Malvavisco, escoba dura, antiphlogistic, antidiarrheal activity alkaloid; hypaphorine methyl ester: afata, afata hembra, mata Dried leaf, decoction: for indole alkaloid; daucosterol: sterol alfalfa infections, skin sores and rashes, Leaf. Quercetin: flavonol Krapovickas 6543 (CORD) and antidiarrheal Dried root. Betaine; choline: Leaf + root, infusion: antidiarrheal and for dysentery Root juice: for gonorrhea BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LRI, MEN, MIS, SAL, SDE, SJU, SLU, TUC Sphaeralcea bonariensis Entire plant, decoction: anti- No biological test Flower + leaf. Alkaloids (Cav.) Griseb. emetic, antitussive Malvavisco, malva del zorro Root + leaf: emollient, Hunziker 13818 (CORD) carminative, anti-inflammatory, antidiarrheal, digestive Leaf + flowers: antiphlogistic, digestive, antidiarrheal, anti- emetic, expectorant Leaf: cicatrizant, for vaginal infections BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, SAL, SDE, SFE, SJU, SLU, TUC Sphaeralcea brevipes (Phil.) Part not specified: diuretic, No biological test No data Krapov. emollient Hunziker 18451 (CORD) CAT, LRI, MEN, SJU, SLU, TUC Sphaeralcea cordobensis Aerial parts: anti-inflammatory, No biological test No data KURTZIANA Krapov. emmenagogue, antihemorrhoidal, Malva, malva dulce antimicrobial, cicatrizant, and for Cuezzo 2464 (LIL) hepatic and intestinal disorders Leaf: cicatrizant, for vaginal infections COR, SDE, SLU

BARBOZA, G.E.etal.MedicinalfloraofArgentina Sphaeralcea mendocina Part not specified: anti- No biological test No data Phil. inflammatory, emollient Hunziker 21378 (CORD) BAI, CHU, LPA, MEN, NEU, RNE, SLU Sphaeralcea miniata (Cav.) Part not specified: anti- No biological test No data Spach inflammatory, emollient Hunziker 6848 (CORD) BAI, CAT, CHA, COR, FOR, LRI, MEN, RNE, SDE, SJU, SLU, TUC Sphaeralcea philippiana Part not specified: diuretic, No biological test No data Krapov. emollient Ruiz Leal 4832 (CTES, LP) MEN, SJU Tarasa antofagastana (Phil.) Leaf: febrifuge, cephalalgic, No biological test No data Krapov. laxative Subils et al. 3891 (CORD) CAT, COR, JUJ, LRI, MEN, SAL, SJU, SLU, TUC Tarasa tenella (Cav.) Leaf: febrifuge, cephalalgic, No biological test No data Krapov. laxative Hunziker19185 (CORD) CAT, JUJ, LRI, MEN, SAL, SJU, TUC Wissadula wissadifolia Young leaf: febrifuge No biological test No data (Griseb.) Krapov. JUJ, SAL Tolaba 2858 (CORD) MARTYNIACEAE Ibicella lutea (Lindl.) Van Dried leaf, infusion: resolutive, Dried aerial parts: antibacterial Dried aerial parts. Apigenin: flavone; Eselt. emollient, as eye wash activity 3-acetyl-24-epi-polacandrin and 1,3- Cuernos del diablo, astas del Flowers + seed: emollient, diacetyl-24-epi-polacandrin: diablo pectoral expectorant dammarane triterpenes; 20S,24S-epoxy- Hunziker 12013 (CORD) Seed: ophtalmic 3β-,12β-,25-trihydroxydammarane; 11- BAI, CHA, COR, COS, DFE, ERI, O-(6´-O-acetyl-β-D-glucopyranosyl)- LPA, LRI, MEN, SAL, SDE, SFE, stearic acid. SLU, TUC Ibicella parodii Abbiatti Part not specified: emollient, No biological test No data Hunziker 12332 (CORD) ophtalmic, resolutive

CAT, COR, JUJ, LRI, MEN, SAL, 249 SDE, SJU, SLU, TUC

250 MELASTOMATACEAE Miconia calvescens DC. Medicinal No biological test No data Tomo34(1-2):7-365.2009 Morrone 3549 (SI) MIS, SAL MELIACEAE Cabralea canjerana (Vell.) Part not specified: for snakebites, Aerial part: typanocidal activity Stem. 20S,24S-epoxy-7β,25-dihydroxy- Mart. cephalalgic, for puerperal 3,4-secodammar-4(28)-en-3-oic acid, Cajarana, kacharana infections 20S,24S-epoxy-7β,15α,25-trihydroxy- Zuloaga 5611 (SI) Bark: for skin diseases 3,4-secodammar-4(28)-en-3-oic acid COS, MIS and 20S,24R-epoxy-7β,22ξ,25- trihydroxy-3,4-secodammar-4(28)-en-3- oic acid, ocotillone, eichlerianic acid, shoreic acid: dammarane triterpenes; sitosterol, campesterol, stigmasterol, sitostenone, stigmast-5-en-3-: sterols; escopoletin: coumarin Cedrela balansae C. DC. Bark: febrifuge No biological test No data Cedro del cerro, cedro CAT, JUJ, SAL, TUC salteño, cedro orán Venturi 5767 (SI) Cedrela fissilis Vell. Bark + leaf: febrifuge, emetic, Dried entire plant: toxic effect; Root + leaf. Gedunin, 6α- Cedro astringent, hepatic, urinary trypanocidal activity acetoxygedunin, 7-deacetoxy-7- Lillo 10446 (CORD) disorders, abortifacient oxogedunin, 1,2-dihydro-3β-hydroxy-7- Bark: for influenza and headache deacetoxy-7-oxogedunin, 7- COS, MIS, SAL, TUC deacetylgedunin, photogedunin Root. 3β-acetoxycarapin, 7-deacetoxy- 7-oxogedunin, gedunin, photogedunin: limonoids; hispidol A, piscidinol A, pentaol, nilocetin, odoratol, iso- odoratol, odoratone, 11-oxooleanonic KURTZIANA acid, oleanonic acid, oleanolic acid: triterpenes Fruit + seed. Fissinolide, mexicanolide and 3β-hydroxyisomexicanolide: limonoids

Cedrela odorata L. Fresh entire plant,infusion: for Bark: plant germination Stem bark. D-Octacosan-1-ol: alkanol BARBOZA, G.E.etal.MedicinalfloraofArgentina Cedro vertigo inhibition, antimalarial activity C5 or more; 11β-acetoxyobacunyl Fortunato 7043 (BAB) Bark: astringent, analgesic, Stem bark: antifeedant activity acetate, 11β,19-diacetoxy-1-deacetyl-1- febrifuge, emetic, tonic for anemia, Stem bark + wood: antibacterial epidihydronomilin, 11β- as a remedy for diarrhea, anti- activity acetoxyobacunol, odoralide: inflammation, hemorrhage and Fresh leaf: vasodilator activity nomilin/obacunol derivatives; 8β,14α- indigestion; decoction: astringent, dihydroswietenolide: for gangrene dihydroswietenolie; 7- MIS, SAL acetyldihydronomilin, 7-acetyl-11β- acetoxydihydronomilin: nomilin derivatives; 3β,6- dihydroxydihydrocarapin, swietenolide, xyloccensin, 3β- hydroxydihydrocarapin, cedrodorin: mexicanolides Stem. Calamenene, cycloeucalenol, sitosterol, stigmasterol, campesterol, gedunin, 7-deacetylgedunin, 7- deacetoxy-7-oxogedunin, methylangolensate, febrifugin, azadiradione, 20,21,22,23-tetrahydro- 23-oxoazadirone, 3β- deacetylfissinolide, catechin; 1α- methoxy-1,2-dihydrogedunin: limonoid; 3β-O-β-D- glucopyranosylcydoeucalenol cycloartane; gedunin, nimbin, nimbolide: limonoids Leaf. Cedrodorin: triterpene Seed. Andirobin: triterpene Essential oil. Calamenene: sesquiterpene. Guarea macrophylla subsp. Bark: astringent, anti-arthritic No biological test Dried leaf. Cycloarta-23-25-dien-3- spicaeflora (A. Juss.) T. D. Part not specified: for lumbago one: triterpene; labda-8-trans-13-dien-

Penn. and heart pain 15-ol: diterpene; β-sitosterol: sterol; 251 Cedrillo CHA, COS, FOR, MIS, SFE spathulenol: sesquiterpene Krapovickas 2402 (CTES)

252

Trichilia catigua A. Juss. Bark, infusion: mental tonic, Dried bark: antibacterial and Stem. 7-hydroxy-1-oxo 14-nor Tomo34(1-2):7-365.2009 Catiguá,catiguá colorado, sexual stimulant, styptic analgesic activity calamenene: sesquiterpene catiguá-guazú, catinga Plant, infusion or decoction: Dried bark. Cinchonains Ia and Ib: Deginani 1011 (SI) purgative, antirheumatic, tonic, flavalignans sexual stimulant Aril. Cedrelone, 11β- CHA, COS, FOR, MIS, SDE methoxycedrelone, methylangolensate, photogedunin epimeric mixture: limonoids Trichilia pallida Sw. Part not specified: stomachache No biological test Leaf. Cyanogenic glycosides Cedrillo COS, FOR, MIS Root. Limonoids Eskuche 417 (SI) MENISPERMACEAE Cissampelos ovalifolia DC. Aerial parts: diuretic, diaphoretic, Root: neuromuscular blocking Rhizome. Warifteine hydrochloride, Oreja de burro, oreja de mono antirheumatic, stomachic, and local anaesthetic activity¸ dimethylwarifteine (O- Keller 4018 (CTES) febrifuge, for snakebites antiprotozoal activity methylcissampereine): alkaloids; Root: diuretic, diaphoretic, bisbenzylisoquinoline alkaloids febrifuge MIS Cissampelos pareira L. Entire plant, infusion: Dried leaf: antibacterial and Root bark. Curine,(-): isoquinoline Zarza, zi pó, m il hom bres, emmenagogue, febrifuge, diuretic, anti-haemolityc activity alkaloid charrúa, caá pevá blennorrhagia, for enteralgia, Leaf + root + stem: antioxidant Dried root. Hayatine, pareirubrine A, Hunziker 24827 (CORD) diarrhea, and stomach-ache, tonic, activity roraimine, warifteine: isoquinoline resolutive, venereal diseases, for Leaf + stem: hypotensive alkaloids the cystitis activity Aerial parts, infusion: to prevent threatened miscarriage, to stop uterine hemorrhages; decoction:

hepatic KURTZIANA

BARBOZA, G.E.etal.MedicinalfloraofArgentina Cissampelos pareira L. Root: pregnancy pains; sexual (continuation) stimulant, emmenagogue, relief of abdominal pains, rheumatic pains, headache, snakebite, blenorragia, haematuria, colic diuretic, solvent of urinary calculi, bitter tonic, purgative and antiperiodic in dyspepsia and diarrhoea, cough, sore trotas, colds, febrifuge, externally used for scabies, abscesses and sores, malaria, emetic. Twig bark: diuretic, diaphoretic Leaf, decoction: febrifuge, for venereal disease, bites, stings, and skin rashes; infusion: antiseptic, for whooping cough, conjunctivitis, and syphilis Leaf + root, decoction: febrifuge Fresh leaf juice: for abdominal pain Leaf pulp: abortive CAT, CHA, COS, FOR, JUJ, MIS, SAL, SDE, SFE, TUC MENYANTHACEAE Nymphoides indica (L.) Part not specified: bitter tonic No biological test Dried entire plant. Kaempferol, Kuntze BAI, COS, ERI, FOR, SFE, TUC quercetin: flavonol Soldanella de agua Ariza Espinar 1230 (CORD) MISODENDRACEAE Misodendron punctulatum Entire plant: against stomach Plant: antioxidant and free No data DC. ailments radical scavenging activity Injerto CHU, NEU, RNE, SCR, TDF Diem 3160 (SI) 253

MOLLUGINACEAE 254 Mollugo verticillata L. Leaf + stem: antimicrobial Dried aerial parts: Dried entire plant. Sterol Molugo, inambú-pisá BAI, CAT, CHA, COR, COS, ERI, immunomodulatory activity Tomo34(1-2):7-365.2009 Cantero et al. s.n. (RIOC 631) FOR, LPA, LRI, MIS, RNE, SAL, SDE, SFE, SLU, TUC MONIMIACEAE Hennecartia omphalandra Part not specified: antispasmodic, No biological test Fruit essential oil. Bicyclogermacrene; α- J. Poiss. for lumbago, cephalalgic, and β-phelandrene; germacrene D; α – Cabrera 28794 (SI) febrifuge, contraceptive, nervine, bulnesene, valerianol, β-pinene, sabinene, stomachic β-myrcene, Δ-3-carene, α- and γ- COS, MIS terpinene, p-cymene, terpinolene, α- cubebene, dodecanal, β-elemene, α- gurjunene, E-caryophyllene, trans-α- bergamotene, aromadendrene, α-guaiene, α-humulene, seychellene, α-bulnesene, α- muurulol, α-bisabolol, β-silenene, trans-β- guaiene, γ-muurolene, γ- and δ-cadinene, ledol, sphatulenol, guaiol, epi-cubenol, cis- cadine-4-eno-7-ol, cubenol. Laureliopsis philippiana Leaf + flowers + bark: sedative, Dried leaf: antibacterial activity Leaf. Laureliopsine A: (Looser) Schodde digestive, respiratory disorders, bisbenzylisoquinoline alkaloid and Tepa, huahuán, laurela emmenagogue, antivenereous, other alkaloids Chiapella 1782 (CORD) cephalalgic, antispamodic CHU, NEU, RNE MORACEAE Dorstenia brasiliensis Lam. Root: tonic-stimulant, sudorific, Dried root: cytotoxic activity Rhizome. Benzoic acid: benzenoid; Contrayerba, higuerilla, febrifuge, emmenagogue, Fresh root: analgesic (sub nom. dorstenic acid B: triterpene; bergapten: hediondito, taropá, taropé alexipharmic, contraceptive D. tubicina) and anti- coumarin; seco-adianane-type Dorstenia tubicina Ruiz & Rhizome, infusion: for malaria, inflammatory activity triterpenoids, isopimarane-type Pav. emmenagogue diterpenoid; steroids, furocoumarins

Arbo 6796 (CTES) Leaf: febrifuge, diuretic, Dried rhizome. α-amyrin; α-tocopherol KURTZIANA diaphoretic (sub nom. D. tubicina) (sub nom. D. tubicina) BAI, CHA, COS, ERI, FOR, MIS Ficus adhatodifolia Schott Leaf (latex): purgative, No biological test No data Zuloaga et al. 682 (SI) vermifuge, vulnerary Fruit: sedative COS, FOR, MIS

Ficus luschnathiana (Miq.) Leaf: purgative No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina Miq. Latex: analgesic Higuera, higuerón, ibapohí, Fruits: sedative agarra-palo, higuera brava, External use: vulnerary higuera salvaje BAI, CHA, COS, ERI, MIS, SFE Zuloaga 5565 (SI) Maclura tinctoria subsp. Bark: against venereal diseases, Dried bark: antiviral activity Dried stem bark. Aromadendrin: mora (Griseb.) Vázq. Avila astringent Dried stem bark: antioxidant flavonoid; naringenin: flavanone Mora CHA, COS, FOR, JUJ, SAL activity Dried leaf. Bavachromanol: flavonoid Fortunato 6512 (BAB) Leaf: antifungal activity (sub Leaf. Isobavachalcones: prenylated nom. M. tinctoria) chalcones (sub nom. M. tinctoria) MYRSINACEAE Myrsine laetevirens (Mez) Aerial parts, decoction: Aerial parts: antimicrobial Seed (endosperm). Xyloglucans and Arechav. toothhache, for skin irritations activity glucans with β- (1→3) and β-(1→4) Morrone 1151 (SI) BAI, CAT, COS, ERI, FOR, JUJ, linkages; pectins, P, K, Mg, Ca MIS, SAL, SFE, TUC Seed (embryo + endosperm). Palmitic, stearic, oleic and linoleic acids; proteins; arabinose, galactose, glucose, xylose, fucose, uronic acids MYRTACEAE Amomyrtella güili (Speg.) Leaf: against bruises, diarrhea, No biological test No data Kausel dyspepsia, gastrointestinal bloating Guayaba SAL, TUC Meyer 20467 (LIL) Amomyrtus luma (Molina) D. Legrand & Kausel Twigs + wood: to soothe pain No biological test Essential oil. Linalool: monoterpene; Luma, palo madroño, caused by internal injures pentan-3-one,1-phenyl: benzenoid; cauchao, cauchahue Plant: stimulant, astringent ˜ caryophyllene: sesquiterpene; 1- Boelcke 5286 (BAB, SI) CHU, NEU, RNE phenyl hexan-3-one: benzenoid Blepharocalyx salicifolius Leaf + bark: antitussive, Leaf: antibacterial activity Aerial parts . 1-8-cineole, (Kunth) O. Berg expectorant, vulnerary, diarrhoea, caryophyllene oxide, α-terpineol α- Anacahuita, arrayán urinary infections pinene, γ-terpinene, verbenol, Blepharocalyx tweediei BAI, CAT, COS, ERI, JUJ, MIS, verbenone, myrtenal, carvone, (Hook. & Arn.) O. Berg SAL, SFE, TUC elimicine; other sesquiterpenes (sub Bacigalupo 1250 (SI) nom. B. tweediei) 255 Leaf essential oil. 1-8-cineole, linalool, β-caryophyllene

256 Campomanesia Leaf: stomach ache, for diarrhoea Leaf: toxic effect (general), Leaf. Flavonoids, saponins, tannins xanthocarpa O. Berg var. Dried leaf, decoction: against antibacterial, antiulcer and Fruit essential oil. α- and β- pinene, α- Tomo34(1-2):7-365.2009 xanthocarpa coughs and enteritis, astringent mutagenic activity; significant phellandrene, limonene, linalool, α- Guabirá, guaviriová, Part not specified: antidiarrheal, reduction in weight gain terpineol: monterpenes; α-cubebene, α- guabirobé, guariva vermicide copaene, β-elemene, β-caryophyllene, β- Ahumada 1484 (SI) COS, MIS gurjunene, aromadendrene, α-humulene, allo-aromadendrene, germacrene D, α- and β-selinene, bicyclogermacrene, α- muurolene, germacrene A, β-bisabolene, β- and γ-cadinene, (Z)-calamenene, cadina- 1,4-diene, germacrene B, bulnesol, (E)- nerolidol, spathulenol, caryophyllene oxide, guaiol, α- and β-eudesmol: sesquiterpenes; hexadecanoic acid, (E)-2- hexanal, hexanal, furfural, benzaldeyde Eugenia involucrata DC. Part not specified: potencial uses No biological test Fruit essential oil. β-elemene, β- Cerella, cereza stomachache caryophyllene, β-selinene, β-gurjunene, Múlgura de Romero 2310 COS, MIS α-humulene, allo-aromadendrene, (SI) germacrene D, α-selinene, α-muurolol, α- and δ-cadinene, cadina-1,4-diene, germacrene B, ledol, spathulenol, caryophyllene oxide, 5-epi- 7-epi-α- eudesmol, guaiol, humulene oxide I, humulene oxide II, 10-epi-γ-eudesmol, iso-spathulenol, 1-epi-cubenol, γ- eudesmol, t-cadinol, t-muurolol, α- eudesmol, α-cadinol: sesquiterpenes Eugenia pitanga (O. Berg) Root: astringent Dried leaf: xanthine oxidase Leaf. Citronellol, geranyl acetate, Kiaersk. Leaf: antirheumatic, balsamic, inhibition geraniol, 1,8-cineol, terpinene, Pitanga hepatic, anthypertensive, digestive sesquiterpenes, and polyterpenes

KURTZIANA Múlgura de Romero 2081 COS, MIS Resin: resin acids, resens, and (SI) resinotannols Eugenia pyriformis Part not specified: antidiarrheal Dried leaf: xanthine oxidase Leaf essential oil. δ-cadinene,α-and τ- Cambess. var. pyriformis COS, MIS inhibition cadinol, bicyclogermacrene, β- Ubajai, ubajai-mí, uvala caryophyllene Morrone 1601 (SI)

Eugenia uniflora L. Dried bark + leaf, infusion: Dried leaf: antibacterial, Dried leaf. Galloyl-β-D-glucose,1-2-4- BARBOZA, G.E.etal.MedicinalfloraofArgentina Arrayán colorado, ñangapirí, hypotensive, astringent, emollient, antifungal, antihypertensive, 6-tetra-o, eugeniFlowersin D-1, D-2, arrayán, ñangapiré, pitanga, for throat affections spasmolytic, antidiarrheal, oenanthein B: tannins; arrayán mato, cereza, morita Leaf: diuretic, emmenagogue, analgesic, cytotoxic, anti- gallocatechin,(+), procyanidin, del monte, arrayán montano digestive, carminative, inflammatory, vasodilator, prodelphinidin: flavonoids; myricitrin, Martínez 339 (CORD) antidiarrheal, for agitation, antioxidant, diuretic, myricetin, quercitrin, quercetin: stomach pain, cough, bronchitis, hypoglycemic, antihyperlipemic, flavonols; piperidine-3-α-4-α-5-β- influenza, hypertension, and antimalarial, triol,(+): alkaloid; uniFlowersine A, B: intestinal troubles; to lower antihypercholesterolemic, and indolizidine alkaloid cholesterol, to treat urinary and antitrypanosomal activity; Leaf essential oil. Furanoelemene, respiratory tract infections, and to maltase, sucrase, xanthine oxidase, furanodiene, β-elemene, delta elemene, reduce weight; to control uric acid glutamate-pyruvate-transaminase allo aromadendrene, levels, antidiabetic, astringent, and DNA polymerase and xanthine bicyclogermacrene, curzerene, eupeptic, antirheumatic, febrifuge, oxidase inhibition; caryophyllene, germacrene B and D, for hernia and prolapse antihypertriglyceridemia effect; furanodiene, globulol, humulene, Fruit, infusion: astringent toxic effect, CNS effects germacrone, trans-trans germacrone, CAT, CHA, COS, ERI, FOR, JUJ, Fresh leaf: antiyeast, ledene, selina-1-3-7(11)-trien-8-one, MIS, SAL, SFE, TUC antimycobacterial, analgesic, selinene, selin-11-en-4-β-ol, antidiarrheal, antibacterial, and spathulenol: sesquiterpenes; para anti-inflammatory activity cymene, camphor, car-3-ene, 1-8- Leaf essential oil: contracting cineol, methyl geranate, myrcene, cis effect ocimene, α-phellandrene, β-pinene, Dried flowers: antispasmodic pulegone, linalool, limonene, and hypotensive activity terpinolene, γ-terpinene, α-styrene: monoterpenes Fruit essential oil. Myrcene, o-cymene, p-cymene, limonene, (Z)-β-ocimene, (E)-β-ocimene: monoterpenes; β- elemene, β-caryophyllene, β-selinene, α-santalene, aromadendrene, α- humulene, allo-aromadendrene, germacrene D, α-selinene, bicyclogermacrene, α-muurolene, α- muurolol, γ-cadinene, δ-cadinene, cadina-1,4-diene, germacrene B, germacra-1-8(11)-dien-9-one,4-

acetoxy, selina-4(14)-7(11)-diene, 257 spathulenol, caryophyllene oxide, globulol, epi-globulol: sesquiterpenes

258 Hexachlamys edulis (O. Dried leaf + stem, infusion: for Dried leaf + stem: toxic effect Dried leaf. Myricitrin, myricetin-3-O- Berg) Kausel & D. Legrand diabetes and gout hypoglycemic and antidiabetic α-L-arabinopyranoside, myricetin-3-O- Tomo34(1-2):7-365.2009 Ubajay, uvajay, iva-jay Dried leaf, infusion: activity β-D-xyloside, avicularin, desmanthin Zuloaga 6566 (SI) hypoglycemic, to lower uric acid Dried leaf: xanthine oxidase 1, myrcetin, myrcetin-3-O-α-L- levels inhibition arabinofuranoside, quercetin: flavonols; CHA, COS, ERI, FOR, MIS, SFE Fresh fruit: xanthine oxidase gallic acid: benzenoid; gallocatechin-3- inhibition O-gallate,epi: (-): flavonoid; galloyl-D- Leaf: angiotensin-converting glucose; tannins; saponins; phenols; enzyme inhibition sterols and/or triterpenes; leucoanthocyanins; polyhydroxyalkaloids (pyrrolizidines and piperidines) Luma apiculata (DC.) Leaf: balsamic, vulnerary, No biological test Aerial parts. Polyhydroxyalkaloids Burret astringent, stimulant, tonic (pyrrolizidines and pyrrolidines) Arrayán, quetri stomachic, antidiarrheal, Fortunato 5794 (BAB) anticatarrhal CHU, NEU, RNE Myrceugenia exsucca (DC.) Bark + leaf: antidiarrheal Dried leaf + stem: xanthine Essential oil. Dimethyl sulfide: sulfur O. Berg CHU, NEU, RNE oxidase inhibition compound; cinnamaldehyde: Patagua, pitra, chillum phenylpropanoid; furfurylaldehyde: Fortunato 5791 (BAB) oxygen heterocycle; linalool, limonene, borneol, bornyl acetate, iso borneol,: monoterpenes; ortho-methoxy benzaldehyde,: benzenoid; butyraldehyde: alkanal to C4 Myrceugenia glaucescens Leaf: astringent, antidiarrheal, No biological test Essential oil. 1-8-Cineol,:monoterpene (Cambess.) D. Legrand & digestive Kausel BAI, COS, ERI, MIS Multa, murta

Keller 109 (CTES) KURTZIANA Myrceugenia planipes Bark: balsamic, antisyphilitic Leaf + stem: cytotoxic activity Aerial parts. Polyhydroxyalkaloids (Hook. & Arn.) O. Berg NEU Boelcke 10548 (CTES)

Myrcianthes cisplatensis Leaf: tonic, astringent, diuretic, Aerial parts essential oil: Aerial parts essential oil. Camphene, BARBOZA, G.E.etal.MedicinalfloraofArgentina (Cambess.) O. Berg stimulant fumigant and repellent activity p-cymene, limonene, α-pinene, β- Guayabo colorado, palo pelado, CAT, COR, COS, ERI, SAL, SFE, against head lice pinene: monoterpene hydrocarbon; δ- vil vil, lapachito, arazá de mon- TUC Leaf: antimicrobial and antiviral cadinene, γ-cadinene, β-caryophyllene: te, arrayán, mato, sacha mato, activity sesquiterpene hydrocarbon; τ-cadinol: güili, güili blanco, ibirá yepiró oxygenated sesquiterpene; Burkart 29399 (SI) conglomerone Myrcianthes pseudomato Essential oil: antimicrobial Essential oil: antimicrobial Essential oil. 1,8-cineole, ß- (D. Legrand) McVaugh JUJ, SAL, TUC activity caryophyllene, α-pinene, linalool, Alpa mato, güili, güili blanco, limonene, γ-terpinene laurel Schreiter 919 (MVM) Myrcianthes pungens (O. Leaf + essential oil: tonic, Aerial parts: antimicrobial Aerial parts. Polyhydroxyalkaloids Berg) D. Legrand astringent, diaphoretic, diuretic activity (pyrrolizidines and piperidines) Mato, guabiyú, guabijú, CAT, CHA, COS, ERI, FOR, JUJ, Fruit: free radical scavenging Leaf essential oil. 1,8-Cineol, nerol, guabirá, ibaviyú,arrayán MIS, SAL, SFE, TUC effect geraniol: monoterpenes; α-pinene; Ahumada 8946 (SI) α-thujene; p-cymene;; β-pinene; myrcene; D-limonene; α-phellandrene; terpinolene; conglomerone Fruit essential oil. α-copaene, β- elemene, β-caryophyllene, α-humulene, germacrene D, bicyclogermacrene, δ- cadinene, cadina-1,4-diene, elemol, globulol, epi-globulol, α-, β- and γ- eudesmol: sesquiterpenes; furfural Myrrhinium atropurpu- Part not specified: antimicrobial Leaf essential oil: antibacterial No data reum Schott var. octandrum CAT, COS, ERI, JUJ, MIS, SAL, activity Benth. TUC Krapovickas 15502 (CTES) Plinia rivularis (Cambess.) Bark: anthelmintic Dried stem: xanthine oxidase No data Rotman COS, ERI, MIS inhibition Vanni 3488 (CTES) Psidium guajava L. Entire plant, infusion: for diarrhea Aerial parts: giardicidal activity Aerial parts. Polyhydroxyalkaloids Guayabo, guayaba, guayabo Bark, infusion: emmenagogue, Dried bark + leaf: antibacterial, (pyrrolidines), tannins and other phenolic amarillo, arazá puitá, guayaba astringent, febrifuge; for anticancer, and anti- compounds, guiajaverin (a glycoside of del monte hypertension, infections, malaria, inflammatory activity quercetin), essential oils, triterpenoids 259 Cocucci 2908 (CORD) rabies, stomachache, and Stem bark: antidiabetic activity Dried bark. Acutissimin A , B: tannin antidysenteric Fresh fruit. Acetone: alkanone to C4; β-bisabolene: sesquiterpene

Psidium guajava L. Dried leaf, decoction: anti-emetic Dried fruit: anti-inflammatory Dried fruit. Arjunolic acid: triterpene 260

(continuation) Fruit: antidiarrheal and analgesic activity Fruit peel essential oil. Caryophyllene Tomo34(1-2):7-365.2009 CHA, COS, FOR, JUJ, MIS, SAL, Fresh fruit: antimutagenic and oxide: sesquiterpene TUC antihyperglycemic activity Leaf essential oil. β-caryophyllene, α- and β-pinene, 1,8-cineole, camphene, myrcene, α-phellandrene, limonene, p- cymene, β-selinene Part not specified: : ; 3,4,5-: phenolic acid Psidium guineense Sw. Leaf: expectorant, antittusive, Fresh leaf essential oil: anti- Leaf essential oil. (Z)-nerolidol, Arazay, arasá ñu, arasá del antidiarrheal inflammatory and antibacterial caryophyllene, β-selinene campo COS, MIS activity Cocucci 3094 (CORD) Fruit: free radical scavenging effect Psidium salutare var. Leaf: resolutive No biological test Leaf + stem essential oil. Camphene, sericeum (Cambess.) Fruit + root: astringent, to treat limonene, ocimene, myrcene, Landrum wounds caryophyllene oxide, ar-turmerone Psidium incanum (O. Berg) (sub nom. P. incanum) (sub nom. P. incanum) Burret Fruit, leaf + root: for treatment of Arazá gastrointestinal disorders and Cocucci 2993 (CORD) hepatic complaints. COS, ERI, MIS, TUC Psidium salutare var. Dried aerial parts, infusion: Dried leaf: antibacterial activity; Leaf + stem essential oil. mucronatum (Cambess.) vulnerary, digestive, xanthine oxidase inhibition Aryophyllene, β-sesquiterpene; Landrum emmenagogue (sub nom. P. luridum) limonene: monoterpene Araza, alpa, alpamato Dried leaf, decoction: to treat Essential oil. 1-8-cineol: monoterpene Psidium luridum (Spreng.) urinary and respiratory tract (sub nom. P. luridum) Burret infections, for diarrhea; infusion: Hunziker 7231 (CORD) carminative Leaf + flowers: digestive,

aromatic, antidiarrheal KURTZIANA (sub nom. P. luridum) COS, ERI, MIS, TUC Siphoneugena occidentalis Medicinal No biological test No data D. Legrand SAL Mato negro, huanquillo Tortorelli s.n. (MVM)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Ugni molinae Turcz. Part not specified: astringent Dried leaf and stem: xanthine Dried leaf. Phytohemagglutinin: Murtilla, murta CHU, NEU, RNE oxidase inhibition protein Dimitri 7692 (BAB) Leaf + stem: cytotoxic and antitumor activity NOTHOFAGACEAE Nothofagus antarctica (G. Part not specified: febrifuge Leaf + stem: cytotoxic activity Leaf + twigs. Hyperoside, quercitrin, Forst.) Oerst. CHU, NEU, RNE, SCR, TDF rutin: flavonols Ñire, ñiró, anís, ñirre, roble Barboza 1215 (CORD)

Nothofagus dombeyi Part not specified: febrifuge, Leaf + stem: cytotoxic activity Leaf + twigs. Hyperoside, quercitrin, (Mirb.) Oerst. analgesic, anti-inflammatory Leaf: antifeedant activity rutin: flavonol Coihue, coygüe, coigüe CHU, NEU, RNE Leaf. Lupeol, cabraleone, 2- and 3-O- Burkart 19923 (SI) acetylmaslinic acids, pectolinarigenin,12-hydroxyoleanolic lactone Fresh seedling. Polypeptide Nothofagus obliqua (Mirb.) Part not specified: febrifuge, Leaf + stem: cytotoxic activity Leaf + twigs. Hyperoside, quercitrin, Oerst. subsp. obliqua antitussive Leaf + twigs: antibacterial rutin: flavonol Roble pillín, roble de NEU activity Neuquén, coyán, pellín Arroyo 996100 (CONC) Nothofagus pumilio (Poepp. Part not specified: febrifuge Leaf: antifeedant activity Leaf. Cabraleadiol monoacetate, β- & Endl.) Krasser CHU, NEU, RNE, SCR, TDF sitosterol, 5- Lenga, roble, roble blanco, hydroxytetramethoxyflavone, betulonic roble lenga, roble de Tierra acid, dihydrooroxylin A, oleanolic acid, del Fuego ursolic acid, maslinic acid, 3-O-acetyl- Fortunato 5762 (BAB) 20,24,25-trihydroxydammarane, and its 3-O-deacetyl derivative NYCTAGINACEAE Bougainvillea stipitata Griseb. Medicinal No biological test No data Huancar, falso tala, espuela CAT, CHA, COR, FOR, JUJ, LRI, de gallo, guancar, alfiler SAL, SDE, SLU, TUC

Hunziker 17012 (CORD) 261

Pisonia zapallo Griseb. var. Root + leaf: emetic, cathartic, No biological test No data 262 zapallo against venereal diseases Palo de zapallo, zapallo caspi, CHA, COS, FOR, JUJ, MIS, SAL, Tomo34(1-2):7-365.2009 yucurubuzú, tupasirí, yuquiruzú SFE, TUC Hunziker 20726 (CORD) NYMPHAEACEAE Nymphaea amazonum Flowers + leaf: against the herpes, Vegetative organs: antioxidant Leaf + stem. Phenolic compounds subsp. pedersenii Wiersema emollient activity Leaf. Tannins, steroid, triterpenes Aguapé guazú Leaf: cicatrizant Root. Tannins and terpenes Pedersen 4494 (CORD) Root: anti-haemorroidal BAI, COS, SFE Victoria cruziana Orb. Flowers: refrigerant, anaphrodisiac No biological test No data Irupé, avatí-yu, victoria regia, CHA, COS, ERI, FOR, SFE fuente, maíz del agua Schinini 27638 (CTES) OLACACEAE Ximenia americana var. Dried leaf + stem, infusion: for Aerial parts: hypotensive and Dried root. β-amyrin: fixed oil, tariric argentinensis De Filipps conjunctivitis antiviral activity acid: lipids Albaricoque, pata Leaf: cathartic Dried leaf: molluscicidal Part not specified. Mandelonitrile Hunziker 5970 (CORD) Fruit + leaf: purgative activity glucoside: cyanogenetic glycoside Dried root, decoction: to treat Dried leaf + stem: antimalarial constipation; infusion: to treat activity cancer, for leprosy Seed: antidysenteric, for dental caries and ear infections BAI, CAT, COS, ERI, JUJ, LRI, MEN, SAL, SDE, SFE, SJU, SLU, TUC ONAGRACEAE Fuchsia magellanica Lam. Dried aerial parts, decoction: Aerial parts: angiotensin- Dried leaf. Astragalin, hyperoside: Aljaba, chilco, tilco, cilco, diuretic, mountain sickness, converting enzyme inhibition, flavonols

silque Cocucci 2140 (CORD) gynecological/obstetric diuretic, hypotensive and KURTZIANA Dried stem, infusion: purgative, antimicrobial activity abortive, emmenagogue Leaf: diuretic, febrifuge, emmenagogue Flowers: refrigerant CHU, NEU, RNE, SCR, TDF, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Ludwigia octovalvis (Jacq.) Leaf: stomach and liver pain Flower + fruit + leaf: Dried entire plant. Orientin, vitexin: P.H. Raven Fruit, decoction: digestive, for antibacterial and antifungal flavones Deginani 1117 (SI) fever, respiratory and pulmonary activity disorders. CHA, COS, ERI, MIS, SFE Ludwigia peplo ides (Kunth) Leaf: emollient, for dermatosis Entire plant: cytotoxic activity Entire plant. Flavonoids P.H. Raven subsp. peploides BAI, CHA, COS, ERI, FOR, MIS, Duraznillo del agua, SAL, SFE, TUC enramada de la tararira Hunziker 12292 (CORD) Ludwigia peruv iana (L.) H. Aerial parts: emollient No biological test No data Hara BAI, CAT, CHA, COS, ERI, JUJ. Duraznillo de agua MIS, SAL, SFE, TUC Zuloaga 5418 (SI) Oenothera affinis Cambess. Leaf + flowers: antiseptic, abluent, No biological test Dried leaf. Hyperoside, quercitrin: Flor de la oración, amapola, vulnerary flavonols flor de San José, suspiros BAI, CAT, CHA, COR, COS, Subils 1082 (CORD) DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Oenothera odorata Jacq. Leaf + stem: to relieve bruises Dried aerial parts: tyrosinase Dried leaf. Iso quercitrin: flavonol Flores de la oración, flores de BAI, CHU, COR, LPA, MEN, inhibition Dried seed. Amino acids; eicosenoic la noche, diego de noche, NEU, RNE, SCR, SJU acid: lipid yerba de San Juan Cotyledons. Hyperoside: flavonol Trelles s.n. (SI 4853) Oenothera stricta Ledeb. ex Part not specified: to relieve No biological test Flowers. γ-linolenic acid: lipid Link subsp. stricta bruises Seed. Prostaglandin F-2-α-, γ-linolenic Flor de San Jose, lámpara, BAI, NEU, RNE, SFE acid: lipids Diego de la noche Pérez Moreau 3302 (BAB) OROBANCHACEAE Agalinis communis (Cham. Aerial parts: diuretic, purgative, No biological test Aerial parts. Aucubin shanziside metil- & Schltdl.) D'Arcy emmenagogue, analgesic ester, 5-deoxypulcheloside I,

Cantero et al. s.n. (RIOC 666) BAI, COR, COS, ERI, FOR, MIS, bartsioside, gardoside-methyl-ester, 8- 263 RNE, SFE, SJU epi-loganin, verbascoside

Agalinis fiebrigii (Diels) Flowers: against earache No biological test No data 264

D’Arcy CAT, JUJ, LRI, MIS, SAL, TUC Tomo34(1-2):7-365.2009 Culli culli Ariza Espinar 3546 (CORD) Agalinis genistifolia (Cham. Aerial parts: diuretic, purgative, No biological test No data & Schltdl.) D’Arcy emmenagogue Hunziker 9825 (CORD) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC Buchnera longifolia Kunth Fruit: hemostatic No biological test No data Hosseus 318 (CORD) Fresh fr uit juice: hem ostatic and for hemorrhages or menorrhagia BAI, CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC OXALIDACEAE Hypseocharis tridentata Rhizomes: antitussive No biological test No data Griseb. JUJ, SAL Berojcho, soldaque, huerca- cho, sullu okka, hueroscho, solda que solda, suelda consuelda, vero, veroj, verujo Guaglianone 3114 (SI) Oxalis adenophylla Gillies Part not specified: analgesic/anti- No biological test No data ex Hook. & Arn. inflammatory Culle colorado CHU, MEN, NEU, RNE, SCR Cocucci 2458 (CORD) Oxalis articulata Savigny Leaf + stem: antiscorbutic, No biological test No data subsp. articulata febrifuge Trébol, vinagrillo, macachín BAI, COR, ERI, LPA, MEN, MIS, de los chanchos, macachín SFE, TUC KURTZIANA morado, maahín rosado Bonzani 102 (CORD) Oxalis brasiliensis Lodd. Plant: antiscorbutic No biological test No data Macachín (sub nom. O. macachin) Oxalis macachin Arechav. BAI, COS, ERI, MIS Múlgura de Romero 2265 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Oxalis conorrhiza Jacq. Leaf + stem: contraceptive No biological test No data Vinagrillo BAI, CAT, CHA, COR, COS, ERI, Hunziker 25082 (CORD) FOR, JUJ, LPA, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Oxalis corniculata L. var. Entire plant: febrifuge, antivenin, Dried aerial parts: inotropic Entire plant. Oxalic acid corniculata for dysentery, vermifuge, diuretic, effect positive Dried leaf. Iso vitexin: flavone Vinagrillo, vinagrillo rastrero, anti-lithic Leaf + stem: hypoglycemic pulguita Leaf: antiscorbutic, febrifuge, activity Hunziker 12439 (CORD) antidysenteric, vulnerary, dysmenorrheal, and dermatosis, for skin diseases, irritations and eye inflammation BAI, CHA, COS, ERI, FOR, JUJ, LPA, MEN, SFE, SJU, TDF Oxalis debilis var. Leaf: emollient No biological test No data corymbosa (DC.) Lourteig BAI, CAT, CHA, COS, ERI, MIS, Cabrera 187 (LP) SAL, SFE, SJU, TUC Oxalis erosa R. Knuth fo. Aerial parts: against toothache No biological test No data erosa CHA, FOR, JUJ, SAL, SDE, TUC Cabrera 34462 (SI) Oxalis erythrorhiza Gillies Part not specified: hepatic, Dried entire plant: antibacterial Aerial part. Embelin: benzoquinone; ex Hook. & Arn. kidney, cholalogue, cardioactive activity alkyl phenols; 3-heptadecyl-5-methoxy- Boldo de la cordillera CHU, LRI, MEN, NEU, RNE, SJU phenol Cocucci 2263 (CORD) Oxalis lasiopetala Zucc. Tuber: digestive No biological test No data Cocucci 3651(CORD) BAI, CAT, COR, COS, ERI, JUJ, LPA, MIS, RNE, SAL, TUC Oxalis niederleinii R. Knuth Leaf: antiscorbutic, febrifuge No biological test No data Hunziker 24854 (CORD) BAI, CAT, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC Oxalis perdicaria (Molina) Plant: antiscorbutic, febrifuge No biological test No data Bertero BAI, COS, ERI, MEN, MIS, NEU, Macachín SFE Cabrera 29289 (SI) 265

Oxalis subacaulis Gillies ex Root +aerial parts: to wash No biological test No data 266 Hook. & Arn. injures, refrigerant Kiesling 4154 (SI) MEN, SJU Tomo34(1-2):7-365.2009 Oxalis valdiviensis Barnéoud Medicinal No biological test No data Culle, vinagrillo CHU, NEU, RNE Cocucci 2152 (CORD) Oxalis yacutulensis R. Part not specified: icteric No biological test No data Knuth CAT, LRI, SAL, SDE, TUC Venturi 8091 (SI) PAPAVERACEAE Argemone hunnemannii Entire plant, root, latex + No biological test No data Otto & A. Dietr. flowers: medicinal Cardo santo, cardo santo blanco COR, LPA, MEN, SLU Cantero et al. s.n. (RIOC 418) Argemone subfusiformis Aerial parts: hair care (dandruff Aerial parts: antimalarial, Aerial parts. Berberine, chelerythrine, G.B. Ownbey and seborrhea) antifungal, hypotensive and anti- protopine, allocriptopine, sanguinarine, Cardo santo, cardo amarillo, Leaf + latex: narcotic, hypnotic, HIV activity activity dihydro-sanguinarine, nor-hydro- cardo bendito, cardo blanco, sedative, for treating wounds Dried flower, fruit, leaf, stem: sanguinarine, angoline, O- cardón santo, carrazán, externally, cicatrizant, ophtalmic; antibacterial activity methylzanthoxyline, norchelerythrine, ortiguilla to relieve the stomachache, Leaf: antitumoral activity 6-acetonyldihydrosanguinarine, 6- Argemone mexicana L. auct. pectoral, anti-ulcer Seed oil: antibacterial activity acetonyldihydrochelerythrine, non Root: purgative, emetic (sub nom. A. mexicana) aronttianamide, dihydrocheilantifoline: L. Flowers: emollient, maturating isoquinoline alkaloids; N- Subils 2766 (CORD) Dried petals, infusion: for asthma, demethyloxysanguinarine, pancorine: stomachic, purgative benzophenanthridine-type alkaloids; Dried capsule, infusion: (+)-argenaxine [(+)-1,2,3,4-tetrahydro- antispasmodic 1-(2-hydroxymethyl-3,4- Fresh fruit juice, infusion: dimethoxyphenylmethyl)-6,7- narcotic methylenedioxyisoquinoline], (+)- Seed + latex: febrifuge, higenamine, (+)-reticuline: diaphoretic benzylisoquinoline-type alkaloids; BAI, CAT, CHA, CHU, COR, argemexicaine A, argemexicaine B, KURTZIANA COS, DFE, ERI, FOR, JUJ, LPA, benzo[c]phenanthridine (±)-6- LRI, MEN, MIS, SAL, SDE, SFE, acetonyldihydrochelerythrine; α- SJU, SLU, TUC tocopherol, phytol, stigma-4-en-3,6- diene, adenine, adenosine, isorhamnetin-3-O-β-D-glucopyranoside Seed: Sanguinarine, dihydro- sanguinarine, nor-hydro-sanguinarine (sub nom. A. mexicana)

Bocconia integrifolia Humb. Root: vulnerary, for hernia and Dried leaf + stem bark: Dried leaf. Dihydro chelerythrine: BARBOZA, G.E.etal.MedicinalfloraofArgentina & Bonpl. prolapse antileishmanial activity isoquinoline alkaloid Suncho amargo, mil hombres, Leaf, stembark + latex: cutaneous palo amarillo leishmaniasis Bocconia pearcei Hutch. JUJ, SAL, TUC Morrone 4462 (SI) PASSIFLORACEAE Passiflora caerulea L. Dried aerial parts, infusion: Dried aerial parts: CNS Dried aerial parts. Caffeic acid: Granadilla, flores de la sedative, antispasmodic, depressant activity phenylpropanoid; coumarin, pasión, pasionaria antiscorbutic, diuretic, anti-icteric, Stem: antifungal activity umbelliferone: coumarins; harman: Subils 2299 (CORD) emmenagogue; decoction: to treat indole alkaloid; chrysin, cyanogenic urinary and respiratory tract glycoside sulphate tetraphyllin B-4- infections, for diarrhea, catarrh and sulphate, epitetraphyllin B-4-sulphate pneumonia Leaf. Gynocardin: alicyclic; Flower, fruit, stem + leaf: sedative, schaftoside: flavone anxiolytic, cordial, anthelmintic, calmative, eupeptic, diuretic, emmenagogue, contraceptive Root: antispamodic, antiphlogistic, toxic, narcotic, emmenagogue, sedative, contraceptive, anthelmintic Leaf: hypotensive, bradicardic, anticephalalgic, sedative Seed: hypnotic BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Passiflora capsularis L. Leaf: vermifuge, narcotic, No biological test Leaf. Hydrocyanic acid: inorganic; Guaglianone 2991 (SI) Root: antidysenteric, linamarin: alkanol to C4 antispamodic, cardiotonic Fresh leaf. Passicapsin: alicyclic; Part not specified: abortifacient, cyanogenic bisglycoside 4-bi- emmenagogue vinosyltetraphyllin B MIS Passiflora cincinnata Mast. Leaf + twigs, infusion: for fertility Aerial parts: antioxidant Dried aerial parts. Harmine: indole Mburucuyá, patchio regulation activity alkaloid 267 Barboza 1270 (CORD) Part not specified: abortifacient CHA, FOR, JUJ, SAL

268 Passiflora edulis Sims Entire plant, decoction: for Dried aerial parts: Leaf + stem. (2R)–β-D-allopyranosyloxy-2- Granadilla, maracayú anemia anxiolytic effect, antifungal phenylacetonitrile and (2S)–β-D- Tomo34(1-2):7-365.2009 Biganzoli 444 (SI) Dried aerial parts, infusion: for activity allopyranosyloxy-2-phenylacetonitrile epilepsy and tetanus; sedative, Dried leaf: barbiturate Dried leaf. (22R),(24S)-22,28-epoxy-24- diuretic, anthelmintic, potentiation methyl-1α,3β,24,28-tetrahydroxy-9,19-cyclo- antidiarrheal, stimulant, tonic, for Fresh leaf: diuretic activity 9β-lanostan-4-oic acid β-D-glucosyl ester (= hypertension, menopausal Fruit: tranquilizing effect; Passiflorine): cyclopropane triterpine; luteolin- symptoms, and colic of infants inhibition of of matrix- 6-C-chinovoside, luteolin-6-C-fucoside, Leaf: hemostatic, febrifuge, for the metal-loprotease-2 and cyclopentenoid cyanohydrin glycosides treatment of symptoms of matrix-metalloprotease-9; passicapsin, passibiflorin, cyanogenic alcoholism, anxiety, migraine, anxiolytic activity glycosides passicoriacin, epipassicoriacin and nervousness and insomnia epitetraphyllin B, cyanogenic-β-rutinoside {(R)– Flower: to treat asthma, bronchitis mandelonitrile-α-L-rhamnopyranosyl-β-D- and whooping cough glucopyranoside}, amygdalin, prunasin, Fruit: for intestinal tumors, to treat mandelonitrile rhamnopyranosyl-β−D- anxiety, insomnia, asthma, glucopyranoside, sambunigrin, 6-O-α-L- bronchitis and urinary infection arabinopyranosyl-β-D-glucopyranosides of Seed oil: as a stimulating lubricant linalool, benzyl alcohol and 3 methyl-but-2en-1- and massage oil ol, β-D-glucopyranoside and 6-O-α-L- COS, MIS rhamnopyranosyl-β-D-glucopyranoside of methyl salicylate and β-D-glucopyranoside of eugenol: glycosides; 4-Hydroxy-β-ionol, 4- oxo-β-ionol, 4-hydroxy-7,8-dihydro-β-ionol, 4- oxo-7,8-dihydro-β-ionol, 3-oxo-α-ionol, isomeric 3-oxo retro-α-ionols, 3-oxo-7,8- dihydro-α-ionol, 3-hydroxy-1,1,6-trimethyl- 1,2,3,4-tetrahydronaphthalene vomifoliol and dehydrovomifoliol, linalool, α-terpeneol, (Z)- 2,6-dimethyl-octa-2,7-diene-1,6-diol, 2,6- dimethyl-octa-3,7-dien-2,6-diol, 2,6- dimethyl- 1,8-octanediol, 2,6-dimethyl-octa-1,7-diene-3,6-

diol, ionol derivatives oxygenated in position 3, KURTZIANA and 2,5-dimethyl-4-hydroxy-3-(2H)-furanone (furaneol), ionones I and II; harman, harmine, harmaline, harmalol: alkaloids. Phytoene, phytofluene, α-carotene, neurosporene,

Passiflora edulis Sims β-carotene, lycopene, prolycopene, BARBOZA, G.E.etal.MedicinalfloraofArgentina (continuation) monoepoxy-β-carotene, β-cryptoxanthin, β- citraurin, antheraxanthin, violaxanthin, neoxanthin, α-carotene, γ-carotene, α- cryptoxanthin, β-apo-carotenol: carotenoids; L- ascorbic acid; cyanidin-3-O-β-glucopyranoside and cyanidin-3-O-β-galactopyranoside, cyanidin-3-glucoside, cyanidin-3-6″-malonyl glucoside, pelargonidine-3-glucoside: anthocyanins; γ-hexa, γ-deca and γ- docecalacetone; γ-hepta, γ-octa and γ-nona lactone, alkylated γ-lactones: γ-lactones; esters, 3-methyl-thiohexan-1-ol, 2-methyl-4-propyl-1, 3-oxathione enantiomers, edulans I and II: hexyl caproate, ethyl caproate, limonene, 2- tridecanone, (9Z)-octadecenoic acid, 2- pentadecanone, hexadecanoic acid, 2- tridecanol, octadecanoic acid, caryophyllene oxide; proline, aspartic acid, glutamic acid, serine, alanine: amino acids; carbohydrates; enzyme cytoplasmic pyruvate kinase; cycloartane triterpenes, cyclopassifloic acids A–D, and their saponins, cyclopassiflosides I– VI Fruit. Carbohydrate, calcium, magnesium, phosphorus, potassium, sodium, zinc, copper, selenium, ascorbic acid, thiamin, riboflavin, niacin, Vitamin A, B6, B12, E, K, folate; luteolin-6-C-chinovoside, luteolin-6-C-fucoside, vitexin, isovitexin, orientin, isoorientin, homoorientin, saponarin, saponaretin: flavone glycosides; rutin, quercetin: flavonols; pelargonidin, delphinidin, cyaniding: ; prunasin, sambunigrin: cyanogens; amygdalin, mandelonitrile rhamnopyranosyl β-D-glucopyranosides,

mandelonitrile β-rutinosides 269 Seed oil. Palmitic acid, stearic acid, arachidic acid, oleic acid, linoleic acid and linolenic acid

270 Passiflora elegans Mast. Medicinal No biological test No data Tomo34(1-2):7-365.2009 Legname 7885 (LIL) COS, ERI, MIS Passiflora foetida L. var. Entire plant: antiphlogistic, Dried and fresh leaf: Dried aerial parts. Pachypodol, 7,4’- foetida infusion: to ease hypertension, for antimicrobial and antioxidant dimethoxyapigenin, , 4’,7-O- Granadilla epilepsy and insomnia, activity dimethyl-naringenin, 3,5-dihydroxy-4,7- García 17 (CORD) antispasmodic dimethoxy flavanone, chrysoeriol, Root: for treating wounds apigenin, isovitexin, vitexin, 2’’- externally, emmenagogue, icteric, xylosylvitexin, luteolin-7-β-D-glucoside, for abortion kaempferol: flavonoids; tetraphyllin A, Leaf, infusion: to treat asthma, tetraphyllin B, tetraphyllin B sulphate, hysteria and insomnia; tension deidaclin, volkenin: cyanohydrin regulator glycosides; linoleic acid, linolenic acid: Flowers: pectoral fatty acids; passifloricins: α-pyrones BAI, CAT, CHA, COR, COS, Fresh leaf. Apigenin,4-7-di-O-methyl: FOR, JUJ, LRI, MIS, SAL, SDE, flavone SFE, SJU, SLU, TUC Passiflora misera Kunth Aerial parts: sedative, cordial No biological test No data Mbrucuya’í, meloncito del BAI, CHA, COS, ERI, FOR, MIS, campo, mburucuyá colorado SAL, SFE Barboza 1538 (CORD) Passiflora mooreana Hook. Entire plant + pericarp: No biological test No data f. antidysenteric Granadina, pasionaria, grana- Leaf: antidiabetic, nervine dilla Root: antidiarrheal Di Fulvio 452 (CORD) BAI, CHA, COR, FOR, SAL, SDE, SFE, TUC Passiflora palmatisecta Root: antidiarrheal No biological test No data

Mast. CAT, CHA, COR, FOR, LRI, KURTZIANA Granada, granadilla, SAL, SDE, TUC granadilla pedernida Cocucci 17160 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Passiflora suberosa L. Entire plant, decoction: for No biological test Aerial parts. Passisuberosin, Chiarini s.n. (CORD 596) indigestion epipassisuberosin: cyanogenic Leaf: febrifuge, diaphoretic, glycosides; stomachic, to treat skin diseases; cyanidin-3-(6’’-malonylglucoside), 3- arterial pressure control, diabetes glucoside of cyanidin, delphinidin, Flowers: cordial, sedative petunidin, pelargonidin and anthocyanin Root, decoction: emmenagoge and acetylated with malonic acid: in hysteria anthocyanins CAT, CHA, COR, COS, ERI, FOR, Leaf. Gynocardin, passisuberosin: JUJ, LRI, MIS, SAL, SFE, TUC alicyclics; orientin: flavone Fresh leaf + stem. Tetraphyllin A: alicyclic Fresh fruit. Chrysanthemin: flavonoid Passiflora tenuifila Killip Medicinal No biological test Dried aerial parts. Harmine: indole Granadilla CAT, CHA, COS, FOR, JUJ, MIS, alkaloid Schinini 30287 (CTES) SAL, TUC Passiflora umbilicata Fruits: against diarrhea, gastro- No biological test No data (Griseb.) Harms intestinal disorders Granada CAT, JUJ, LRI, SAL, TUC Hunziker 19084 (CORD) PHYLLANTHACEAE Phyllanthus niruri L. Entire plant, infusion: to treat Dried aerial parts: Aerial parts. Niruriside; phyllanthin, Hunziker 9248 (CORD) hypoglycemic, purgative antihepatotoxic, diuretic, hypophyllanthin, triacontanal, triacontanol; Helechito, rompe piedras Aerial parts: antilithic, diuretic, central analgesic, antibacterial, geraniin, furosin: ellagitannins; ellagic acid, antimicrobial, hypoglycemic, and antiviral activity (influenza brevifolin carboxylic acid, ethyl brevifolin hypotensive, emetic, vermifuge, A virus); smooth muscle carboxylate; glycoflavones; 4- febrifuge; decoction: for diarrhea and relaxation; inhibitory effect on methoxynorsecurinine, nirurine: alkaloids; tuberculosis, to treat venereal diseases crystal growth; reduces urinary astragalin, isoquercitrin, quercetin, Fresh leaf, infusion: for calcium; inhibitor of DNA- quercitrin, rutin: flavonoids; hypoglycemic, diuretic polymerase (wild and Y181C hypophyllanthin, lintetralin, niranthin, Green root, infusion: to treat types) and RNase H activities nirtetralin, phyllanthin, phyltetralin: lignans; heavy menstrual periods phyllester: phthalic ester; corilagin: BAI, CHA, COR, COS, ERI, JUJ, ; 2-(3,4,5)-trihydroxy-6- MIS, SAL, SFE, TUC hydroxymethyltetrahydropyran-2- yloxymethyl)acrylonitrile: cyanoglucoside 271

Phyllanthus sellowianus Aerial parts: antidiabetic, diuretic, Dried entire plant: analgesic Dried stem bark. Caffeic acid: 272 (Klotzsch) Müll. Arg. drastic, antihipertensive, anti- and diuretic activity, cell phenylpropanoid; campesterol: steroid; Sarandí blanco ashmatic, vulnerary proliferation inhibition; cupressuflavone,4'-4'''-di-O-methyl: Tomo34(1-2):7-365.2009 Schinini et al. 18396 (CORD) Dried stem bark, infusion: hypoglycemic effect flavonoid; iso fraxidin: coumarin antidiabetic. Leaf + stem: antifungal activity; Dried leaf + stem. Phyllanthimide: Bark and leaf: antidiabetic, anti- immunomodulating properties alkaloid; phyllathol: triterpene; septic, diuretic, drastic, antidiarrheal Dried root: antiviral activity xanthoxyline. Leaf, infusion: for hypoglycemic Dried stem bark: DNA Dried root. Glochidone: triterpene BAI, CHA, COS, ERI, MIS, SFE, polymerase and ribonuclease TUC inhibition PHYRMACEAE Mimulus glabratus Kunth Stem + leaf: hepatic No biological test Stem. Sterases var. glabratus Leaf, juice: tonic Berro, berro de la sierra, BAI, CAT, CHU, COR, JUJ, LPA, berro silvestre, berro criollo, LRI, MEN, NEU, RNE, SAL, berro hembra, oruro SCR, SFE, SJU, SLU, TUC Caro 3272 (CORD) Mimulus luteus L. var. luteus Part not specified: refrigerant No biological test Flowers. Quercetin 7-O-glucoside, Berro amarillo, flor de mono, BAI, CAT, CHU, JUJ, LRI, MEN, quercetin 3-O-glucoside, kaempferol 7-O- palca, berro NEU, RNE, SAL, SCR, SJU, TDF, glucoside, kaempferol 3-O-glucoside, Barboza 1233 (CORD) TUC apigenin 7-O-glucoside, 7-O- glucoside, luteolin 7-O-glucoside, cyaniding 7-O-glucoside: flavonoids PHYTOLACCACEAE Petiveria alliacea L. var. Entire plant, infusion: diuretic, Dried entire plant: cytotoxic Dried entire plant. Andrographolide: alliacea laxative, abortive, remedy for activity; prostaglandin synthesis diterpene; barbinervic acid: triterpene; Pipí, pimentón, calauchín, stomach cramps, for toothache; inhibition isoarborinol, isoarborinyl-innamate, calaj’chin, calaschi decoction: for pancreatic cancer, Dried leaf: antiproliferation sulphide compounds Hunziker 24342 (CORD) anti-inflammatory and antibacterial activity Leaf. Leridal, leridol, leridol 5-methyl Root: menstrual diseases, breast’s Dried root: anti-inflammatory ether; dihydrokaempferol-3-0-α- disease activity rhamnoside (engeletin), Leaf + root: antirheumatic, dihydroquercetin 3-0-α-rhamnoside KURTZIANA diuretic, antipyretic, vermifuge, (astilbin), myrcetin 3-0-α-rhamnoside abortifacient, sudorific, (myricitrin) antispasmodic, hydrogogue, Dried stem. β-Sitosterol: steroid cordial, antiphlogistic Dried root. Dibenzyl sulfide: sulfur Dried leaf, infusion: for compound rheumatism CHA, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Phytolacca dioica L. Dried entire plant: febrifuge, Entire plant: antimicrobial Leaf. Ombuoside: flavonol; dioicin 1, Ombú, calamaic, moro- vulnerary, vermifuge, antiseptic activity dioicin 2: ribosome-inactivating lawén, zumbí Leaf, bark + root: drastic, emetic, proteins (RIPs); PDL1, PD-L2, PDL3, Martínez 598 (CORD) anti-rrheumatic, antiseptic, PD-L4 (N-β-glycosidase): type 1 RIPs astringent, vulnerary Fresh flowers. Fructose: carbohydrate Dried leaf: purgative Dried seed. Phytolacca protein: protein; BAI, CHA, COS, DFE, ERI, FOR, PD-S2: ribosome-inactivating protein MIS, SAL, SFE, SLU, TUC Rivinia humilis L. Fruit: vulnerary No biological test Plant. β-carotene; betanin 3-sulphate Sangre de toro, fruta tinta, BAI, CAT, CHA, COR, COS, Fruit. Humulixanthin, 5- inchiquil DFE, ERI, FOR, JUJ, LRI, MIS, hydroxynorvaline Cantero et al. s.n. (RIOC 611) SAL, SDE, SFE, SLU, TUC PIPERACEAE Peperomia aceroana C. DC. Part not specified: refrigerant, No biological test No data Krapovickas 47454 (CTES) carminative, antispamodic CHA, COS, FOR, JUJ, MIS, SAL, SFE Peperomia alata Ruiz & Plant: for infections, used in No biological test Aerial parts essential oil. α- Pav. pregnancy and facilitate birth ethylbutyraldehyde, (E) 2-methyl-3- Anís del monte, anís JUJ, SAL nonene, benzaldehyde, 1- Pierotti 80 (LIL) ethylmethylcyclohexane, 3,4- dihydroxy-2,5-dimethyl-1,5-hexadiene, o-cymene, 1,8-cineole, limonene, verbenone, trans-carveol, carvone, 3- cyclohexene-1-carboxyaldehyde, tridecane, β-elemene, β-phenylethyl isobutyrate, ledol, phenylethyl caproate, kongol Peperomia arifolia Miq. Medicinal No biological test No data Anís del monte JUJ, MIS, SAL Tressens 6509 (CTES) Peperomia fiebrigii C. DC. Plant: to induce abortion, galactogene, No biological test No data Siemprevida grande, neonatal and paediatrics care, for congojita, siemprevida, hernia and prolapse, mensual diseases, siempreviva, used in pregnancy and facilitate birth,

Cabrera 30916 (SI) post partum pains and diseases 273 JUJ, SAL

274 Peperomia tetraphylla (G. Plant: galactogene, for infections, Aerial parts: antimicrobial Entire plant. Peperotetraphin (=methyl Forst.) Hook. & Arn. var. hernia and prolapse, neonatal and activity rel-(1R,2S,3S)-2,3-bis(7-methoxy-1,3- Tomo34(1-2):7-365.2009 tetraphylla paediatrics care, to expel the benzodioxol-5- Siempreviva chica placenta and as protective post yl)cyclobutanecarboxylate: Novara 10997 (CORD) partum, used in pregnancy and cyclobutane-type norlignan; methyl facilitate birth (2E)-3-(7-methoxy-1,3-benzodioxol-5- CAT, JUJ, MIS, SAL, TUC yl)prop-2-enoate: phenylpropanoid; α- asarone, vanillic acid, veratric acid, Peperomia theodori Trel. Plant: menstrual diseases, used in No biological test No data Siempreviva, siemprevida pregnancy and facilitate birth Venturi 2053 (SI) JUJ, SAL, TUC Piper aduncum L. var. Dried flower + leaf + stem, Leaf + inflorescence: Dried leaf. Aduncamide: isoquinoline aduncum decoction: digestive, for female antileishmanial activity alkaloid; adunctin A, B, C, D: flavonoids; Matico, falso matico, hierba disorders like menstrual pain, Dried flower + leaf + stem: benzo-1-3-dioxole,5-methoxy-6-(2- del soldado, mucu mucu, hemorrhage and childbirth, antifungal and antibacterial propenyl); 2,6-dimethoxy-4-(2-propenyl) matico chico stomachic, hemostatic activity phenol; methyl 2-methoxy-5-(3’-methyl- Piper elongatum Vahl Leaf, infusion: for gonorrhea, as a Leaf + fruit essential oil: 1’-oxo-2’-butenyl)benzoate (aduncumene): Novara 3584 (MCNS) remedy for diarrhea and antifungal activity prenylated benzoic acid; methyl 2,2- stomachache, antiseptic, diuretic, Essential oil: antibacterial dimethyl-8-(3’-methyl-2’-butenyl)-2H-1- hemostatic, digestive, balsamic, activity benzopyran-6-carboxylate, methyl 2,2- vulnerary, CNS stimulant dimethyl-2H-1-benzopyran-6-carboxylate, COS, FOR, JUJ, MIS, SAL methyl 8-hydroxy-2,2-dimethyl-2H-1- benzopyran-6-carboxylate, 2,2-dimethyl- 2H-1-benzopyran-6-carboxylic acid, 4- methoxy-3-(3´,7’-dimethylocta-2’-E-6’- dienyl)benzoic acid: chromenes; 2’,6’- dihydroxy-4’-methoxydihydrochalcone, piperaduncine B: dihydrochalcones Leaf essential oil. α- and β-pinene, limonene, cis-ocimene, trans-ocimene, linalool: monoterpenes; α-copaene, β-

elemene, α-copaene, β-elemene, α- KURTZIANA gurjunene, β-caryophyllene, aromadendrene, α-humulene, seichelene, germacrene D, bicyclogermacrene, α- muurolene, γ-cadinene, δ-cadinene, germacrene B, nerolidol, spathulenol, globulol, undecanone

Piper aduncum L. var. Stem essential oil. α-and β-pinene, BARBOZA, G.E.etal.MedicinalfloraofArgentina aduncum myrcene, α-terpinene, p-cimene, (continuation) limonene, cis-ocimene, trans-ocimene, γ-terpinene, linalool: monoterpenes; β- caryophyllene, α-humulene, nerolidol: sesquiterpenes Dried fruit. 2'-6'-dihydroxy-4'- dimethoxy dihydro chalcone: flavonoid Fruit essential oil. α- and β-pinene, myrcene, α-terpinene, limonene, 1,8- cineol, cis-ocimene, trans-ocimene, γ- terpinene, linalool: monoterpenes; β- caryophyllene, α-humulene, germacrene D, nerolidol: sesquiterpenes Piper amalago L. Leaf: diuretic, abortive, for kidney Leaf: anti-inflammatory activity Leaf essential oil. α-pinene, camphene, Pari’paroa problems, against skin disorders sabinene, α-copaene, α-cadinol, β- Piper medium Jacq. CHA, COS, FOR, JUJ, MIS, SAL, pinene, myrcene, p-cimene, limonene, Zuloaga 6682 (SI) SDE, SFE, SJU borneol, bornyl acetate, β- caryophyllene, γ-muurolene, δ- cadinene, elemol, spathulenol, caryophyllene oxide, viridiflorol Root. 2-methoxy-4-5-methylenedioxy- trans-cinnamoyl piperidide, 2-methoxy- 4,5-methylenedioxy-trans-pyrrollidide: trans-cinnamoylamides; ishwarol: sesquiterpene Piper hieronymi C. DC. var. Leaf: kidney pain, fever No biological test No data hieronymi CAT, JUJ, SAL, TUC Biurrun 6709 (CORD) Piper mikanianum (Kunth) Root: for amenorrhea and No biological test Fresh leaf essential oil. Safrol, β- Steud. var. mikanianum leukorrhea vetivone, (Z)-isoelemicin, (E)-asarone, Krapovickas 2499 (SI) Leaf: wounds wash, antibiotic, β-caryophyllene, velarianol, nootkatone urinary tract and general infection Part not specified: antidiarrheal,

febrifuge, vermicide, maturating, 275 cephalalgic MIS

276 Piper regnellii (Miq.) C. DC. Leaf: antitussive, expectorant Leaf: antibacterial and Leaf. Eupomatenoid-6, eupomatenoid- Pariparoba Leaf + root: for the treatment of antifungal activity 5, eupomatenoid-3, conocarpan: Tomo34(1-2):7-365.2009 Piper regnellii var. pallescens wounds, swellings and skin Leaf, steam + root: neolignans (C. DC.) Yunck. irritations antimicrobial activity Leaf essential oil. Myrcene, trans- Piper fulvescens C. DC. (sub nom. P. regnellii var. (sub nom. P. regnellii var. anethole, ishwarane Pedersen 6532 (SI) pallescens) pallescens) (sub nom. P. regnelii var. pallescens COS, MIS and P. fulvescens)

PLANTAGINACEAE Angelonia gardneri Hook. Aerial parts: alexipharmic No biological test No data Kermes 142 (BAB) CHA, COS, FOR, MIS, SFE Angelonia integerrima Part not specified: antispamodic, No biological test Dried leaf. Ajugol, harpagide Spreng. stomachic daunoside: iridoid monoterpene Angelonia, conejito del CHA, COS, ERI, FOR, MIS, SFE campo, conejito campestre, jarrita de la perdiz Barboza 1666 (CORD) Bacopa monnieri (L.) Aerial parts: diuretic, Aerial parts: cognition- Aerial parts. Bacoside A3, bacopaside Pennell antirheumatic; nervine tonic for enhancer, antidepressant, II, bacopasaponin C isomer, Berrillo promoting mental health and antioxidant, antiulcerogenic bacopasaponin C and bacopaside I: Cantero et al. s.n. (RIOC improving memory brain function agent, and calcium antagonist; saponins; 3-O-[β-d-glucopyranosyl- 1246) BAI, CAT, CHA, COR, COS, DFE, broncho-vasodilatory activity (1 → 3)-β-d-glucopyranosyl] ERI, FOR, JUJ, LRI, MEN, SAL, jujubogenin, 3-O-[β-d-glucopyranosyl- SDE, SFE, SJU, SLU, TDF, TUC (1 → 3)-β-d-glucopyranosyl] pseudojujubogenin: triterpenoid glycosides

Monttea aphylla (Miers.) Plant: hepatic No biological test Dried shoots. Apigenin: flavone; 3-epi KURTZIANA Benth. & Hook. var. aphylla BAI, CAT, CHU, LPA, LRI, betulinic acid: triterpene; penduletin: Mata de sebo, retama, MEN, NEU, RNE, SAL, SJU, flavonol retamo, elcuí, ala de loro SLU, TUC Cocucci 1348 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Plantago australis Lam. Entire plant: pectoral, Dried entire plant: antiviral Fresh entire plant. Aucubin: iridoid subsp. australis anticatarrhal, emollient, analgesic, activity monoterpene; verbascoside: Llantén, siete varas, lengua anti-inflammatory, for post- Dried fruit: antiulcer and anti- phenylpropanoid, salidroside de vaca, llantén blanco, partum, bladder and kidney inflammatory llantín diseases, for cystitis, wounds and Dried root, leaf + fruit: anti- Filippa 20 (CORD) vaginal discharge inflammatory activity Root: for infections, hernia and prolapse Leaf: astringent, vulnerary, abluent, used in pregnancy and facilitate birth Seed: laxative BAI, CAT, CHU, COR, COS, ERI, JUJ, LPA, LRI, MEN, NEU, RNE, SAL, SCR, SFE, SJU, SLU, TUC Plantago berroi Pilg. Plant: astringent, emollient, No biological test No data Boelcke 11995 (SI) depurative, digestive BAI Plantago brasiliensis Sims Dried leaf, infusion: anti- Dried branch + leaf: antiviral Dried leaf. Alkaloids Llantén inflammatory activity Ariza Espinar 1610 (CORD) Part not specified: astringent, emollient, digestive CHU, COR, COS, ERI, NEU, RNE, SLU Plantago myosuros Lam. Leaf: astringent, abluent, No biological test Entire plant. Aucubin: iridoid Llantén emollient, digestive, hepatic glucoside; verbascoside, plantalloside: Filippa 16 (CORD) BAI, CHA, CHU, COR, COS, caffeoyl phenylethanoid glycosides ERI, FOR, JUJ, LPA, MEN, MIS, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC Plantago orbignyana Steinh. Entire plant: against ocular and No biological test No data ex Decne. subsp. orbignyana skin diseases constipation, against Llantén blanco muscular cramps, to speed up Cabrera 18950 (LP) parturition JUJ, SAL 277

Plantago sericea var. Entire plant: astringent, Aerial parts: antibacterial No data 278 lanuginosa Griseb. vulnerary, anti-cancer activity Tomo34(1-2):7-365.2009 Chauqui llantén, icho-icho CAT, JUJ, SAL, TUC Venturi 4721 (SI) Plantago tandilensis (Pilg.) Plant: astringent, emollient, No biological test Aerial parts. Epiloganic acid, gardoside, Rahn depurative, digestan, anticancer hookeroside, aucubin,catalpol, 10- Plantago brasiliensis var. (sub nom. P. brasiliensis var. bonzoylcatlapol, globularin, globularicisin, tandilensis Pilg. tandilensis) verbascoside, poliumoside, salidroside, 2- Correa s.n. (SI) BAI [4-(β-glucopyranosylloxy)phenyl]acetic acid: iridoids Plantago tomentosa Lam. Entire plant: antitumor; ash: No biological test Aerial parts. Geniposidic acid, 10-O- subsp. tomentosa cicatrizant acetyl geniposidic acid, epiloganic acid, Llantén, llantén velludo, Leaf and root: astringent, gardoside methyl ester, hookeroside, llantén peludo, llantín blanco vulnerary, abluent, stomachic, aucubin: iridoids Plantago paralias Decne. antitussive, anti-haemorrhoidal, Filippa 13 (CORD) anti-inflammatory, analgesic, emollient, pectoral, Dried leaf, decoction: to treat urinary and respiratory tract infections, antidiarrheal Seed: laxative BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Scoparia dulcis L. Aerial parts, infusion: expectorant Aerial parts: analgesic, Aerial parts. Scoparinol: diterpene; Hiel de tierra, flor de febrifuge, anti-haemorrhoidal, antiviral, anti-inflammatory, cirsitakaoside: flavone; scopadulciol, casamiento hepatic, gastric disorders, skin antibacterial, antihyperlipidemic, glutinol, scopadulcid acid A and B, Scoparia nudicaulis Chodat wounds, antidiarrheal, insect and antidiabetic, and acacetin: terpenoids; scoparic acid, & Hassl. snakebites, to control ectoparasites, antiglucoronidase activity scoparic acid A and B: labdane-type

Cocucci 3136 (CORD) bladder and kidney inflammations diterpene acids; alkaloids, tannins, KURTZIANA CHA, COS, ERI, FOR, JUJ, MIS, saponins, cardiac glycoside, SAL, SDE, SFE, TUC phlobatannin Scoparia ericacea Cham. & Medicinal No biological test Aerial parts. Geniposidic acid, Schltdl. CHA, COS, ERI, FOR, JUJ, MIS, geniposide, scandoside-methyl-ester, Yerba de la víbora SAL, SFE, TUC shanziside-methyl-ester, caryoptoside, Zuloaga 7690 (SI) verbascoside

BARBOZA, G.E.etal.MedicinalfloraofArgentina Scoparia montevidensis Entire plant, infusion: No biological test No data (Spreng.) R.E. Fr. emmenagogue, to treat urinary and Cancha del agua, canchalagua respiratory tract infections, Scoparia grisebachii Fritsch anticephalic, hepatic; decoction: Hunziker 11451 (CORD) against diarrhea, to control ectoparasites Aerial parts: emmenagogue, analgesic, vulnerary, stomachic BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LPA, MIS, SAL, SDE, SFE, SLU, TUC Stemodia ericifolia (Kuntze) Entire plant, infusion: No biological test No data K. Schum. contraceptive Novara 11176 (CORD) CHA, COS, FOR, SAL, SFE Veronica peregrina L. Leaf: stimulant No biological test Dried entire plant. Chrysoeriol, subsp. xalapensis (Kunth) BAI, CAT, CHA, CHU, COR, luteolin: flavones; mannitol: Pennell COS, DFE, ERI, JUJ, LPA, LRI, carbohydrate Morrone 3709 (SI) MEN, MIS, NEU, RNE, SAL, SCR, SFE, TDF, TUC PLUMBAGINACEAE Armeria maritima (Mill.) Entire plant, infusion: astringent Seeds: antibacterial activity Leaf. β-alanine: N-methyl: protein; Willd. Part not specified: antinephritic kaempferol, quercetin: flavonol; siempreviva CHU, COR, MEN, NEU, RNE, glycine-betaine: alkaloid-misc Hunziker 9048 (CORD) SCR, TDF Limonium brasiliense Leaf + root: antirheumatic, to Root: Bacteriostatic, anti- Root. Myricetin 3-O-α- (Boiss.) Kuntze relieve bruises inflammatory and antioxidant rhamnopyranoside, (-)-epigallocatechin Guaycurú, calaguala Root: hepatic, antidysenteric, activity; ocytocin and bradykinin 3-Ogallate, (-)-epigallocatechin, (+)- Hunziker 9420 (CORD) astringent, to treat hemorrhage, antagonism gallo catechin, gallic acid. menstrual disorders, rheumatism BAI, CHU, ERI, LPA, MEN, NEU, RNE, SCR, SFE Plumbago caerulea Kunth Leaf: hepatic No biological test Dried leaf. Myricetin-3-glucoside: Jazmín del cielo, plumbago Dried part not specified, infusion: flavonol; plumbagin: quinoid Di Fulvio 261 (CORD) to kill insects embedded under the 279 skin and for varmints COR, JUJ, LRI, SAL, SLU, TUC

280 POLYGALACEAE Bredemeyera colletioides Part not specified: anti-hemostatic No biological test No data Tomo34(1-2):7-365.2009 (Phil.) Chodat CAT, LRI, MEN, SJU, TUC Hualán, hualán blanco, quillay, azahar de la sierra Ariza Espinar 1294(CORD) Bredemeyera microphylla Part not specified: against No biological test No data (Griseb.) Hieron. var. venereal diseases microphylla BAI, CAT, CHU, LPA, LRI, Forcone 157 (CORD) MEN, NEU, RNE, SJU, TUC Monnina dictyocarpa Leaf: antidysenteric, stomachic, Aerial parts: antioxidant No data Griseb. digestive, emetic, balsamic, for activity Quelén bruises (sub nom. P. dictyocarpa) Pteromonnina dictyocarpa BAI, CAT, CHU, COR, ERI, LPA, (Griseb.) B. Eriksen LRI, MEN, NEU, RNE, SAL, Cocucci 2606 (CORD) SCR, SJU, SLU, TUC Monnina lorentziana Part not specified: antidiarrheal, No biological test No data Chodat digestive Quelén, CAT, LRI, MEN, SAL, SJU, SLU, Kiesling 8956 (SI) TUC Polygala australis A.W. Root: expectorant, emetic No biological test No data Benn. BAI, ERI, SFE Polígala Correa 5128 (SI) Polygala brasiliensis L. Root: expectorant, emetic No biological test No data Polígala BAI, COS, ERI, MIS Grüner 1449 (LP) Polygala gnidioides Willd. Root: hepatic, for respiratory and No biological test No data Quelén-quelen intestinal disorders KURTZIANA Boelcke 5973 (SI) CHU, NEU, RNE Polygala linoides Poir. var. Root: expectorant, emetic No biological test No data linoides BAI, COR, COS, ERI, MIS, SFE Polígala Kurtz 10400 (CORD)

Polygala molluginifolia A. Fresh root: contraceptive No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina St.-Hil. & Moq. CHA, COS, ERI, FOR, JUJ, MIS, Martínez 367 (CORD) SAL, SFE, TUC Polygala pulchella A. St.- Root: antitussive, expectorant, No biological test No data Hil. & Moq. emetic Polígala BAI, CAT, CHA, COS, ERI, JUJ, Múlgura de Romero 581 (SI) MIS, SAL, SFE, TUC Polygala stenophylla A. Root: expectorant, emetic No biological test No data Gray BAI, CHU, COR, LPA, LRI, Hunziker 14756 (CORD) MEN, NEU, RNE, SJU, SLU POLYGONACEAE Coccoloba argentinensis Speg. Part not specified: digestive No biological test No data Granadillo, membrillo del CHA, COS, ERI, JUJ, SAL, SFE, monte, cocoloba, te criollo TUC Arbo 7960 (CTES) Coccoloba cordata Cham. Bark stem + bark root: astringent No biological test No data Duraznillo morado, mantor CAT, CHA, FOR, JUJ, MIS, SAL, Cerana 1002 (CORD) TUC Muehlenbeckia hastulata Plant: montain sickness Aerial parts + root: oxytoxic Aerial parts + root. Epicatechin, (Sm.) I. M. Johnst. var. Bark: depurative and analgesic activity emodin-8-glycoside, rutin hastulata MEN, NEU, SJU Root: anti-hypertensive Quilo, voqui negro, zarzaparrilla Kiesling 7733 (SI) Muehlenbeckia sagittifolia Aerial parts: diuretic, hepatic Aerial parts: antibacterial Dried aerial parts. Alkaloids (Ortega) Meisn. Dried leaf + root: to treat syphilis, activity Zarzaparrilla colorada, astringent, diuretic zarzaparrilla Root: depurative, cardiotonic, Subils 2154 (CORD) cordial, astringent, vulnerary BAI, CHA, COR, COS, ERI, FOR, JUJ, MEN, MIS, SAL, SDE, SFE, TUC Muehlenbeckia tamnifolia Leaf, infusion: liver pain, Dried bark: capillary Root. Emodin, chrysophanic acid:

(Kunth) Meisn. febrifuge, to regulate blood permeability increased quinoids 281 Hunziker 8812 (CORD) pressure, and for aphtha. CAT, JUJ, SAL, TUC

282 Polygonum acuminatum Aerial parts: diuretic, Aerial parts: antifungal activity Leaf. Polygodial Kunth hypotensive, astringent, anti- Tomo34(1-2):7-365.2009 Lagunilla, sanguinaria del haemorrhoidal, vulnerary, agua hemostatic, antidysenteric, Hunziker 18236 (CORD) vermifuge Leaf + shoot, infusion: for menstrual pains BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MIS, SAL, SDE, SFE, SLU, TUC Polygonum hispidum Kunth Aerial parts: vulnerary Aerial parts: antibacterial No data Duraznillo del agua Leaf: cicatrizant activity Hunziker 16843 (CORD) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, SAL, SDE, SFE, TUC Polygonum Entire plant: emmenagogue, Aerial parts: antifungal and Root. Triterpenes and/or steroids, hydropiperoides Michx. var. vermifuge, anti-inflammatory, antibacterial activity coumarins, flavonoids, polyphenols, hydropiperoides antihaemorrhoidal, antidiarrheal tannins, saponins Lagunilla, pimienta del agua, Aerial parts: abluent, rubefacient, barbasco diuretic, antirheumatic Bernardello 193 (CORD) Leaf: astringent, anti- haemorrhoidal BAI, CAT, CHA, CHU, COR, COS, ERI, JUJ, LPA, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Polygonum punctatum Entire plant: antidiarrheal, Plant: antibacterial, antiviral, Dried aerial plant. Cinnamolide Elliott astringent, anti-haemorrhoidal, antifungal, anti-inflammatory, Leaf. Danilol: sesquiterpene; Picantilla, catay colorado, emmenagogue, diuretic, analgesic, hipotensive, polygodial: drimane type dialdehyde caá-tí, caá-tay, ajisillo, tripa abortifacient; infusion: for internal antihistaminic activity sesquiterpene de pollo, sanguinaria, ulcers, parasiticide, cicatrizant, Leaf: antidiarrheal and anti- picantilla disinfectant and a vulnerary in the pyretic activity KURTZIANA Subils & Articó 416 (CORD) lavages of pimples, wounds and rash, for haemorrhoids Leaf: for treating wounds externally, abluent, antiseptic, astringent, rubefacient, vulnerary

Polygonum punctatum Elliott BARBOZA, G.E.etal.MedicinalfloraofArgentina (continuation) Flowers, leaf + root: antimicrobial Dried flowers: vermifuge, diuretic, against hemorrhoids. Root, infusion: to treat influenza Juice plant: for dermatosis BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, NEU, SAL, SDE, SFE, SJU, SLU, TUC Polygonum stypticum Part not specified: astringent, No biological test No data Cham. & Schltdl. anti-haemorrhoidal Cien nudos BAI, CHA, COR, ERI, LPA, LRI, Hosseus 364 (CORD) MEN, NEU, RNE, SAL, SFE, SJU, TUC Rumex cuneifolius Campd. Leaf: emollient, antiphlogistic, Aerial parts: antibacterial No data Lengua de vaca vulnerary; decoction: for activity Cantero et al. s.n. (RIOC dermatitis, poultice, emmenagogue 4143) Root: stimulant, purgative BAI, CAT, CHU, COR, JUJ, NEU, RNE, SAL, SFE, SLU Rumex romassa J. Rémy Leaf: diuretic, emollient, No biological test No data Lengua de vaca, pusco yuyo vulnerary, refrigerant Boelcke 6260 (SI) NEU, RNE, SAL Ruprechtia apetala Wedd. Bark: diuretic No biological test No data Manzano del cam po, higue- CAT, CHA, COR, FOR, JUJ, LRI, rilla, higuerón, viraró, virarú SAL, SDE, SFE, SLU, TUC Hunziker 10514 (CORD) Ruprechtia salicifolia Cortex: bitter tonic No biological test Leaf. Terpenes; tanins; saponins; (Cham. & Schltdl.) C.A.Mey. COS, ERI, MIS flavonoids; glycosides Viraró, rama negra, sarandí negro, mata negra Schulz 7098 (LIL) Ruprechtia triflora Griseb. Dried bark + root, infusion: for Aerial parts: antibacterial Dried aerial parts. Lupeol: triterpene; Palo estaca, sacha membrillo, skin eruptions; antidiarrheal, activity β-hydroxy stigmast-5-en-7-one,3-: duraznillo colorado, antitussive steroid; acylated sterol, 5α, 8α- duraznillo Leaf: anti-asthmatic; decoction: epidioxyergosta-6,22-dien-3β-yl 283 Martínez 605 (CORD) antidiarrheal stearate CHA, FOR, JUJ, SAL, SDE, TUC

PORTULACACEAE 284

Calandrinia affinis Gillies Part not specified: alexipharmic No biological test No data Tomo34(1-2):7-365.2009 ex Arn. MEN, NEU, RNE, SJU Luti 5683 (CORD) Cistanthe densiflora Part not specified: anticephallic, No biological test No data (Barnéoud) Hershkovitz cicatrizant Cocucci 25 (CORD) MEN, SAL, SJU Montiopsis gilliesii (Hook. & Leaf: digestive No biological test No data Arn.) D. I. Ford LRI, MEN, NEU, SJU Hunziker 24583 (CORD) Portulaca cryptopetala Leaf: refrigerant No biological test No data Speg. BAI, CHA, COR, COS, ERI, FOR, Hunziker 8141 (CORD) JUJ, MIS, SAL, SFE, TUC

Portulaca grandiflora Hook. Leaf: diuretic, refrigerant Part not speciefied: Entire plant. Betalamic acid: betaxantin Flor de seda, flor de un día, Plant juice: to treat swelling antimutagenic effect ; Dried entire plant. Portulic lactone: pique BAI, CAT, CHU, COR, COS, ERI, antiHBsAg capability diterpene Hunziker 8718 (CORD) JUJ, LPA, LRI, MEN, NEU, RNE, Dried leaf. Adenine: alkaloid SAL, SFE, SJU, SLU, TUC Fresh flowers. Betanin: betaxantin Callus tissue. Epinephrine: isoquinoline alkaloid Portulaca umbraticola Kunth Entire plant: emollient No biological test No data Verdolaga CAT, CHA, COR, FOR, JUJ, LRI, Hunziker 10656 (CORD) MIS, SAL, SDE, SJU, TUC Anagallis alternifolia Cav. Entire plant: ophtalmic Leaf + stem: cytotoxic activity No data var. alternifolia MEN, NEU, RNE, SCR, TDF Boelcke 13968 (SI) PROTEACEAE

Embothrium coccineum J. Bark + leaf: vulnerary, Leaf + stem: cytotoxic activity No data KURTZIANA R. Forst. & G. Forst. antineuralgic, dermatologic Notro, ciruelillo, notru, magú CHU, NEU, RNE, SCR, TDF Cocucci 2414 (CORD) Gevuina avellana Molina Entire plant: antidiarrheal, for Dried seed: antioxidant activity, Kernel oil + pericarp (shell). Oleic Cocucci 3485 (CORD) venereal disease radical scavenging effect acid, hexadecenoic acid CHU, NEU, RNE

Lomatia ferruginea (Cav.) Entire plant: carminative, Dried leaf + stem: antibacterial Seed. Lawsone, valdivione: quinoid BARBOZA, G.E.etal.MedicinalfloraofArgentina R. Br. purgative, diuretic activity Fuinque, hiunque, palmilla CHU, NEU, RNE, SRC Schajovskoy 25637 (SI) Lomatia hirsuta (Lam.) Leaf + bark: purgative, to wash Dried leaf: antitumor and Dried leaf. Quercetin, rhamnetin: Diels ex J. F. Macbr. injures anti-inflammatory activity flavonols; scopoletin, umbelliferone: Radal, ral ral, rairal, nogal del Dried leaf, decoction: to treat coumarins sur coughs and asthma Bernardello 602 (CORD) Part not specified: analgesic, anti- inflammatory CHU, NEU, RNE QUILLAJACEAE Dried leaf. Quercetin, rutin: flavonol; Quillaja brasiliensis (A. St.- Bark: astringent Barks, leaves + branches: the 19-O-β-D-glucopyranoside of 16- Hil. & Tul.) Mart. COS, MIS adjuvant activity on the immune hydroxylambertic acid: abietane Jabón de palo, árbol del responses to bovine herpesvirus diterpene; prosapogenin (3-O-β-D- jabón, palo jabón type 1 in mice glucuronopyranosyl-quillaic acid), Rodríguez 153 (SI) quercetin, rutin. Barks, leaves + branches: saponins RANUNCULACEAE Anemone de capetala Ard. Leaf + stem: caustic, rubefacient, No biological test No data var. decapetala narcotic Flor de la esperanza, centella, BAI, CHU, COR, ERI, MIS, NEU, ysipó ñaro RNE, SLU Cantero et al. s.n. (RIOC 1716) Anemone multifida Poir. Entire plant: analgesic/anti- No biological test Dried entire plant. Caffeic acid methyl Centella inflammatory; infusion: for ester: phenylpropanoid Cocucci 2151 (CORD) diarrhaea, abortifacient Dried root. Ranunculin: misc lactone CHU, MEN, NEU, RNE, SCR, TDF Caltha sagittata Cav. Root: digestive, against the No biological test No data Cocucci 3666 (CORD) toothache CHU, JUJ, LRI, MEN, NEU, RNE, SCR, SJU, TDF Clematis bonariensis Juss. Leaf: antineuralgic, caustic, No biological test Dried aerial parts. Flavonoids ex DC. rubefacient, antidote, for skin Cabello de vieja, zarza disorders, against the scabies, for

cimarrona dermatosis 285 Fortunato 775 (BAB) Flowers: vulnerary BAI, ERI, MIS

Clematis haenkeana C. Presl Entired plant: against parturition No biological test No data 286 Barba de chivo pain Hunziker 21178 (CORD) CAT, JUJ, SAL, TUC Tomo34(1-2):7-365.2009 Clematis montevidensis Aerial parts: to treat anxiety and Aerial parts: antibacterial and Dried root. Oleanolic acid: triterpene Spreng. var. montevidensis irritability; tonic; for skin mycosis diuretic activity Cabello de ángel, loconte, Leaf, infusion: against skin barba de viejo, barba de affections chivo, tuya-rendiva, bejuco, Flower + leaf: antirheumatic, barba de indio, aloconte caustic Subils 1512 (CORD) BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC Halerpestes cymbalaria Part not specified: caustic, No biological test Dried aerial parts. Ranunculin: misc (Pursh) Greene fungicide, rubefacient lactone Oreja de gato, botón de oro, BAI, CAT, CHU, COR, JUJ, LPA, (sub nom. R. cymbalaria) pura-pura, ranúnculo dentado LRI, MEN, NEU, RNE, SAL, Ranunculus cymbalaria Pursh SCR, SFE, SJU, SLU, TDF, TUC Cantero et al. s.n. (RIOC 2042) Ranunculus apiifolius Pers. Leaf: rubefacient No biological test No data Apio del diablo, apio Part not specified: caustic cimarrón BAI, CHA, ERI, LPA, SDE, SFE, Hunziker 11234 (CORD) TUC Ranunculus bonariensis Part not specified: caustic, No biological test No data var. trisepalus (Gillies ex rubefacient Hook. & Arn.) Lourteig BAI, COR, DFE, ERI, LPA, MIS, Berrito, berro SFE Hieronymus 525 (CORD) Thalictrum decipiens Boivin Root: diuretic, purgative, No biological test No data Albaquilla emmenagogue Subils 1148 (CORD) CAT, COR, JUJ, SAL, SLU, TUC

RHAMNACEAE KURTZIANA Colletia paradoxa (Spreng.) Bark: antiperiodic, purgative, No biological test Root bark. Ceanothic acid; ziziberenalic Escal. tonic, febrifuge acid, betulin acid, ursolic acid, β-sitosterol, Curro, currumamuel, espina Leaf + seed: febrifuge, purgative β-sitosterol glycoside cruz, cura mamuel, espina de Fruit: antispasmodic Aerial parts. Seco-3,4-germanicone, la cruz, crucero, quina BAI ursolic acid, lupeol , betulin acid, ceanothic Tortosa 225 (BAA) acid, taraxerol, taraxerone, seco-3,4- taraxerone, germanicol, germanicone, β- sitosterol, β-sitosterol glycoside

BARBOZA, G.E.etal.MedicinalfloraofArgentina Colletia spinosissima J.F. Entire plant: for alopecia, No biological test Aerial parts. D-(-)-magnocurarine, D- Gmel. dandruff and seborrhoea (-)-1-(4-methoxybenzyl)-2,2-dimethyl- Barba de tigre, coronillo, Stem: bitter tonic, febrifuge, 6-methoxy-7-hydroxy-1,2,3,4- barba de indio, quillarín, tola, astringent; for amnesia; brain tonic tetrahydroisoquinoline (= colletine): tola tola BAI, CAT, COR, COS, ERI, JUJ, alkaloids Cantero et al. s.n. (RIOC LRI, MEN, SAL, SDE, SJU, SLU, 1464) TUC Condalia buxifolia Reissek Plant: antitermic and in the Plant: antinociceptive activity Aerial parts. Condaline, myrianthine Piquillín negro, piquillín negro treatment of dysenteries B, scutianine B, scutianine C: alkaloids Burkart 9952 (SI) CAT, COR, JUJ, LPA, LRI, SAL, TUC Condalia microphylla Cav. Bark: astringent No biological test Heart wood. Tannin Piquillín Flowers + fruit: laxative Dried fruit. Malvidin-3-gentiobioside: Hunziker 6055 (CORD) BAI, CAT, CHU, COR, JUJ, LPA, flavonoid LRI, MEN, RNE, SAL, SDE, SJU, Seed oil. Campesterol, cholesterol: SLU, TUC steroids

Discaria americana Gillies Dried aerial parts, infusion: Aerial parts (flowers, stems + Dried aerial parts + root bark. & Hook. antipyretic leaf) essential oil: antioxidant Betulin acid, β-sitosterol, β-sitosterol Brusquilla, coronillo del Stem + root bark: tonic, febrifuge activity glycoside; triterpenes; ursolic acid, campo, quina del campo, tola Root: for treating wounds externally; ceanothic acid, ferulic acid derivative Cantero et al. s.n. (RIOC decoction: to treat diabetes Dried root bark. Adouetine Y, 1965) BAI, CHU, COR, COS, ERI, LPA, discarene A, B, C, D, M, N, franganine, MEN, RNE, SFE, SLU frangulanine, myrianthine A: cyclopeptide alkaloids; betulinic acid; β-sitosterol (195), β-sitosterol glycoside, β-sitosterol 6'-O-acyl glycoside Aerial parts (flowers, stems + leaf) essential oil. 4-methylphenol, eugenol, 3-methylindole, α-terpineol Discaria chacaye (G. Don ) Bark: for bruises No biological test Dried leaf + stem. 1-2-11-trimethoxy Tortosa CHU, NEU, RNE, SCR, TDF nor Aporphine: isoquinoline alkaloid Espino blanco, chacay de la Cordillera

Cocucci 2141 (CORD) 287

Ziziphus mistol Griseb. Aerial parts: cholagogue, laxative Seed oil: inhibition of models of Young leaf. iso Rhamnetin, 3-O-β-D- 288

Mistol, sacha mistol, mistol Stem ash: emetic mamary neoplasias glucoside, rutin: flavonols Tomo34(1-2):7-365.2009 cuaresmillo Bark, decoction: abortive Seed. α-linolenic acid: polyunsatured Hunziker 9210 (CORD) Leaf, decotion: antidysenteric fatty acid Fruit: pectoral, hepatic, antispasmodic CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, SAL, SDE, SFE, SJU, SLU, TUC ROSACEAE Acaena argentea Ruiz & Entire plant: venereal diseases, Dried aerial parts: cytotoxic No data Pav. diuretic, astringent and antitumor activity Amor seco CHU, NEU, RNE Leaf + stem: hypotensive and Krapovickas 3773 (BAB) anticrustacean activity; β- glucuronidase and xanthine oxidase inhibition. Acaena magellanica (Lam.) Part not specified: for bronchitis, Dried entire plant: analgesic, Aerial parts. Quercetin, Q-3-O-β-D- Vahl urinary, sedant, cholagogue antibacterial, antipyretic, and glucoside, Q-3-O-β-D-galactoside, Abrojo, amor seco, cadillo CAT, CHU, LRI, MEN, NEU, anti-inflammatory activity ellagic acid, catechin; tormentic acid Cocucci 2561 (CORD) RNE, SAL, SCR, SJU, TDF 28-O-β-D-galactopyranoside, 28-O β- D-glucopyranoside: saponins Acaena myriophylla Lindl. Leaf and stem: astringent, No biological test No data Yerba de la vizcachera, cicatrizant, diuretic sanalotodo, cadillo BAI, CAT, COR, ERI, LPA, Krapovickas 6409 (CORD) MEN, RNE, SFE, SLU, TUC Acaena ovalifolia Ruiz & Pav. Root: venereal diseases No biological test No data Abrojo BAI, CAT, CHU, JUJ, NEU, RNE, Cocucci 2127 (CORD) SAL, SCR, TDF, TUC Acaena pinnatifida Ruiz & Leaf: astringent, cicatrizant, for No biological test Dried leaf. Eight urs-12-ene Pav. treating wounds externally, triterpenoids, β-sitosterol, (+)-catechin, Abrojo, cadillo de la tierra, abluent; infusion: diuretic, used apigenin 7-O-glucoside; pomolic acid, pimpinella, cadillo de la during menopause pomolic acid-3-acetate, tormentic acid, KURTZIANA sierra, pimpinela cimarrona Root: venereal diseases, astringent 2-epi-tormentic acid, euscaphic acid, Ariza Espinar 371 (CORD) CAT, CHU, COR, LPA, MEN, tormentic acid glucoside, niga- NEU, RNE, SCR, SJU, TDF ichigoside F1, niga-ichigoside F2. Acaena sericea J. Jacq. Medicinal No biological test No data Cadillo CHU, MEN, SCR, SJU, TDF Belgrano 17 (SI)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Acaena splendens Gillies ex Dried bark + spines, infusion: Dried bark + spines: antipyretic Dried bark + spines. β-amyrin, lupeol, Hook. & Arn. febrifuge, for rheumatism, diuretic, activity: oleanolic acid: triterpenes Abrojo, cadillo, cepa caballo anti-inflammatory, for liver disease. Cocucci 3726 (CORD) Wood, infusion: diuretic, for liver disease Root: febrifuge, stomachic ulcer, astringent, diuretic Part not specified: depurative, diuretic, emmenagogue MEN Geum magellanicum Comm. Part not specified: depurative, No biological test No data ex Pers. diuretic emmenagogue Yerba del clavo CHU, NEU, RNE, SCR, TDF Chiapella 1746 (CORD) Kageneckia lanceolata Ruiz Leaf + stem: febrifuge, emetic Aerial parts: antioxidant Seedling. Prunasin like-glycoside: & Pav. Part not specified, infusion: activity benzenoid Sacha durazno, durazno de la febrifuge, for tertian malaria sierra COR, JUJ, SAL, SDE, SLU, TUC Cantero et al. s.n. (RIOC 1179) Margyricarpus pinnatus Aerial parts: diuretic, Aerial parts: diuretic effect Dried leaf. Alkaloids, flavonoids (Lam.) Kuntze emmenagogue, carminative, Yerba de la perdiz, inambú- purgative, antirheumatic, blood caá, hierba de la perdiz, depurative, abortifacient, for perlita, perlilla dismenorrhoea Hunziker 6994 (CORD) Root and leaf: astringent, cicatrizant, anti-haemorrhoidal, anti-inflammatory, abluent, febrifuge BAI, CHU, COR, ERI, LPA, MEN, NEU, RNE, SAL, SCR, TUC 289

290 Polylepis australis Bitter Leaf: astringent Leaf + bark: antibacterial Dried bark. Oleanolic acid methyl Tabaquillo, queñoa CAT, COR, JUJ, SAL, SLU, TUC activity ester: triterpene; methyl 3β- Tomo34(1-2):7-365.2009 Hunziker 6475 (CORD) Leaf: diuretic activity hydroxyolea-9(11),12-dien-28-oate, methyl 2a,3β-dihydroxy-11oxo-olean- 12-en-28-oate, methyl acetyloleanolate, methyl acetylursolate, methyl obtusilinate, methyl euscaphate, methyl 3β- hydroxyolean-9(11),12-dien-28-oate, methyl 3β-hydroxy-11-oxo-olean-12- en-28-oate, methyl 2α-methoxy-3β- hydroxyolean-12-en-28-oate Potentilla chiloensis (L.) Root: astringent, antidysenteric, Dried leaf: antimycobacterial No data Mabb. antidiarrheal, against venereal activity Frutilla, quillán, quillén, diseases frutilla chilena, llahuén Part not specified: emmenagogue Fragaria chiloensis (L.) (sub nom. F. chiloensis) Duchesne NEU Cocucci 2324 (CORD) Rubus brasiliensis Mart. Root: laxative, diuretic Plant: hypnotic, anxiolytic, No data Mora blanca Leaf: laxative anticonvulsant and muscle Keller 3923 (CORD) Flowers: antispasmodic relaxant effects Fruit + fruit juice: tonic, antidiarrheal MIS Rubus imperialis Cham. & Root, leaf, stem: antidiabetic Root, leaf, stem: cytotoxic and Aerial parts + root . Niga-ichigoside, Schltdl. agent, astringent hypoglycemic activity; 23-hydroxy-tormentic acid, 3-O- Zarza mora, sacha mora, rosa CAT, JUJ, MIS, SAL, TUC antinociceptive effect methylellagic-4’-O-α-rhamnose acid. del monte, mora blanca

Legname 5994 (SI) KURTZIANA Tetraglochin alatum (Gillies Part not specified: diuretic, for the Leaf + stem: cytotoxic activity; Aerial parts. Flavonoids, genins ex Hook. & Arn.) Kuntze var. period following childbirth diuretic effect alatum CHU, MEN, NEU, SJU, SLU Espina de pescado, horizonte Biurrun 5723 (CORD)

Tetraglochin cristatum Aerial parts: antitussive, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina (Britton) Rothm. antidiabetic, febrifuge, for Choquecanguia, canjía, cailla, pneumonia, against cancer sanguía, canguí, canguia, canjía CAT, JUJ, LRI, SAL, TUC morada, canguiya, canlla, cho- que canglia, chocchán, choco- canglia, chojchán, chuquicangia, perlía, conguiya, perlilla, perlita Núñez 617 (CORD) RUBIACEAE Borreria densiflora var. Fresh aerial parts, juice: for Aerial parts: No data perennis Standl. eczema. antibacterial activity Pozner 213 (CTES, SI) Entire plant, decoction: for Leaf: antischistosomal activity diabetes; infusion: to treat bacterial Flower + leaf + stem: skin infections, for leprosy. pheromone Dried flowers, infusion: (sub nom. B. densiflora) antipyretic, analgesic (sub nom. B. densiflora) BAI, CAT, CHA, COR, ERI, FOR, JUJ, SAL, SDE, TUC Borreria verticillata (L.) G. Aerial parts: skin diseases Aerial parts: antimicrobial Aerial parts: β-carbolines; Mey. Part not specified: emmenagogue, activity spermacoceine; borrerine, borreverine, Botón blanco, flor de ipe- emetic Root: antibacterial activity isoborreverine: indole alkaloids cacuana BAI, CHA, COS, ERI, FOR, MIS, Seeds. Trypsin, chymotrypsin, Fortunato 1049 (BAB) SFE subtilisin inhibitors Calycophyllum multiflorum Bark: tonic, antipyretic Aerial parts: antifungal activity No data Griseb. CHA, FOR, JUJ, SAL, SDE Palo blanco, Ibirá-mototí, morotibí Tressens 6311 (CTES) Cephalanthus glabratus Leaf + bark: diuretic, depurative, No biological test Dried leaf. Mitraphylline, pteropodine, (Spreng.) K. Schum. astringent, antidiabetic, vulnerary uncarine E: indole alkaloids; peroxides Sarandí colorado, sarandí BAI, CHA, COS, ERI, MIS, SFE Aerial parts. tetrahydroalstonine, negro mitraphylline, uncarine E: alkaloids;

Arbo 7098 (CTES) ursolic acid: triterpenoids; 3-O-b-D- 291 quinovopyranoside-28-O-b- glucopyranoside; chlorogenic acid 5-O- caffeoylquinic acid; sitosterol

Chiococca alba (L.) C. L. Root: depurative, alexipharmic, Leaf: antifungal activity Leaf. Kaempferitrin, lepidoside, 292 C. brachiata Hitchc. diaphoretic, against venereal (sub nom. ) apigenin, 7-O-methoxyquercetrin, Tomo34(1-2):7-365.2009 Bejuco diseases, tonic for ganglion Root: low acute and subacute quercetrin: flavonoids; 4’- Chiococca brachiata Ruiz & inflammation, diuretic, antiviral, toxicity methoxykaempferol-7-(acetyloxy)-3,5- Pav. anti-eodema, aphrodisiac, to treat Root (saponin brut fraction): O-α-L-rhamnoside: flavonol; α-amirin, Zuloaga 6578 (SI) rheumatic disorders, febrifuge, and anti-inflammatory activity β-amirin, ursolic and oleanolic acids: in snakebite triterpenes; 4-hydrozy-heptadecan-7- COS, MIS one, 5-hydroxyoctadecan-11-one: hydroxyketones; 5, 7, 4’-trimethoxy-4- phenylcoumarin, exostemin : coumarins; matairesino, D-mannitol; linoleic acid, linolenic acid, palmitic acid + others: fatty acids Root. 28-O-α-D-apiofuranosyl (1→3)- α-L-rhamnopyranosyl (1→2)-α-L- arabinopyranosyl 3-O-β-D- glucopyranuronosyl-3β-hydroxyolean- 12,15-dien-28-ate: bidesmosidic oleanane saponin; filic-7-en-3-one, fern-7-en-3-one: pentacyclic triterpenes; α and β-amirin, oleanolic acid, ursolic acid, 3β-hydroxyolean- 12,15-dien-28-oic; merilactone: nor- seco-pimarane; alboside I, alboside II, alboside III: iridoids; alboside IV and V: seco-iridoids Coutarea hexandra (Jacq.) Bark: antipyretic, emetic, laxative, Dried entire plant, cytotoxic Dried stem. Coumarin,5-7-dimethoxy- K. Schum. bitter tonic, febrifuge, activity 3'-4'-methylene-dioxy-4-phenyl; Cascarilla, quina, abortifacient, anti-inflammatory, Dried stem bark: anti- coumarin,4-phenyl: 3'-4'-dihydroxy-5- dominguillo for malaria and, diabetes inflammatory activity 7'-dimethoxy: coumarins Barboza 453 (CORD) COS, JUJ, MIS, SAL Dried stem bark. Coutareagenin: coumarin Galianthe brasiliensis Part not specified: febrifuge, anti- Aerial parts: antiproliferative Aerial parts. Mixture of Z-and E 6-O- KURTZIANA (Spreng.) E.L. Cabral & depressive properties p-Coumaroylscandoside methyl ester, Bacigalupo BAI, COS, ERI, MIS asperuloside, deacetylasperuloside: Morrone 1897 (SI) iridoid glycosides; ursolic acid: triterpene; stigmasterol, campesterol, β- sitosterol and 3-O- β-glycopiranosyl sitosterol: steroids

BARBOZA, G.E.etal.MedicinalfloraofArgentina Galianthe eupatorioides Part not specified: diuretic, No biological test No data (Cham. & Schltdl.) E.L. Cabral depurative Guaycurú COS, MIS, SFE Cocucci 3119 (CORD) Galium bigeminum Griseb. Root and leaf: anti-haemorrhoidal No biological test No data Cantero et al. s.n. (RIOC 746) BAI, COR, COS, ERI Galium eriocarpum Bartl. Medicinal No biological test No data ex DC. MEN, NEU Yerba del pollo Cabrera 11155 (LP) Galium hirtum Lam. Part not specified: antirheumatic No biological test No data Burkart 22763 (SI) BAI, COS, ERI, MIS Galium hypocarpium (L.) Entired plant: depurative blood No biological test Leaf. Linoleic acid, linolenic acid, Endl. ex Griseb. subsp. BAI, CAT, CHU, COR, COS, palmitic acid + others: fatty acids hypocarpium DFE, ERI, JUJ, MIS, NEU, RNE, Coralito SAL, TUC Hunziker 9505 (CORD) Galium latoramosum Clos Plant: to induce abortion, Aerial parts: antifungal activity No data Chipi chape contraceptive Morrone 1282 (SI) BAI, COR, COS, ERI, JUJ, MIS, SFE, SLU, TUC Galium lilloi Hicken Plant: to induce abortion, No biological test No data Chipi chape contraceptive Zuloaga 7845 (SI) CAT, JUJ, SAL, SDE, TUC Genipa americana L. var. Fruit: antisyphilitic, antidiarrheal, Part not specified: increases Leaf. Linoleic acid, linolenic acid, americana astringent, refrigerant, antiasthmatic, bile flow palmitic acid + others: fatty acids Ñapindá, genipapo, genipava, aphrodisiac, antianemic, tonic, Fruit. Butyric, 2-3-methylbutyric, huitoc, yaguá, jenipapo, diuretic, in the spleen and liver hexanoic, methylbutanoic esters; janipab, jenipapeiro, jenipá affections and jaundice methyl hexanoate, methyl and ethyl Tressens 6325 (CTES) Root: purgative octanoate, acetic and 2- CHA, FOR, MIS methylpropanoic acids, vanillin hexadecanoic acid, octadecanoic acid, tetradecanoic acid, linalool, limonene

Part not specified. Geniposidic acid, 293 genipin, genamesides A-D: iridoids

Geophila repens (L.) I. Fresh leaf: for hypertension Plant: antifungal activity Leaf. Fatty acids 294

M. Johnston Plant: to treat fungal infections Frutescent aerial part: Tomo34(1-2):7-365.2009 Deginani 1087 (SI) Fruit: for furunculosis antileishmanial activity Part not specified: odontalgic COS, FOR, MIS Heterophyllaea pustulata Entire plant: antimicotic Stem + leaf: bacteriostatic and Leaf. Heterophylline (1,6-dihydroxy-7- Hook. f. JUJ, SAL, TUC antifungal activity methoxy-2-methylanthraquinone), Cegadera pustuline (2-hydroxy-3-methoxy-7- Cocucci 1326 (CORD) methylanthraquinone): monomeric anthraquinones; (S)-5,5'-bisoranjidiol: bianthraquinone; asperuloside: iridoid glycoside; quercetin, isoquercitrin, and quercetin-3-O-β-d-glucosyl-6' '-acetate: flavonoids Stem. Damnacanthal, rubiadin, 2- hydroxy-3-methyl anthraquinone, soranjidiol, rubiadin-1-methyl ether, and damnacanthol: anthraquinones Machaonia brasiliensis Root: emetic Dried root: cytotoxic activity Leaf. 3β-O-β-glucopyranosyl (Hoffmanns. ex Humb.) CHA, COS, FOR, MIS, SFE stigmasterol, 3β-O-β-glucopyranosyl Cham. & Schltdl. sitosterol, secologanoside, 7-O-β- Pensiero 6103 (SI) glucopyranosyl quercetagetin, 4,5-O- dicaffeoylquinic acid, 5-O- caffeoylquinic acid Manettia cordifolia Mart. Root: emetic No biological test Entire plant. Emetine: isoquinoline Barboza 1565 (CORD) COS, ERI, JUJ, MIS, SAL, TUC alkaloid Mitracarpus megapota- Leaf + stem: febrifuge Aerial parts: antibacterial No data micus (Spreng.) Kuntze BAI, CAT, CHA, COR, COS, activity Peladilla, micus DFE ERI, FOR, JUJ, LPA, LRI, Di Fulvio 197 (CORD) MIS, SAL, SDE, SFE, TUC KURTZIANA Nertera granadensis (Mutis Part not specified: vulnerary Dried aerial parts: Aerial parts. Asperuloside: iridoid ex L. f.) Druce CHU, NEU, RNE, SCR, TDF anticrustacean activity monoterpene; ursolic acid: triterpene Boelcke 5275 (BAB) Palicourea macrobotrys Part not specified: diuretic No biological test No data (Ruiz & Pav.) Roem. & MIS Schult. Correa Luna s.n. (BA, SI)

Pogonopus tubulosus (A. Bark: antiperiodic, febrifuge, tonic Bark: antimalarial activity Dried stem bark. Cephaeline, BARBOZA, G.E.etal.MedicinalfloraofArgentina Rich. ex DC.) K. Schum. Dried stem bark, infusion: used psychotrine, tubulosine: indole Quina, sacha-quina, quina for malaria alkaloids morada, flor del diablo, quina JUJ, SAL, TUC virreina, cascarilla Neumann 418 (CORD) Psychotria carthagenensis Dried part not specified, infusion: No biological test Leaf. Ursolic acid: triterpene; n-methyl Jacq. emetic, antiparasitic, purgative tryptamine: indole alkaloid Chalchal de la gallina, jazmín BAI, CHA, COS, ERI, FOR, JUJ, de la costa, jazmín del monte, MIS, SAL, SFE, TUC naranjillo Cocucci 3086 (CORD) Richardia brasiliensis Root: emetic Aerial parts: antimicrobial and Aerial parts. 3-β-hidroxy-11-en-28,13- Gomes Part not specified: anti-emetic, to antioxidant activity β-olide Di Fulvio 574 (CORD) treat diabetes Leaf + stem. Alkaloids, tannins, BAI, CAT, CHA, COR, COS, ERI, saponins, steroid, terpenoid, flavonoids, FOR, JUJ, MIS, SAL, SDE, SFE, cardiac glycoside TUC Part not specified. Isomerine-3-O- rutinoside Richardia grandiflora Aerial part, decoction: vermifuge, No biological test Entire plant. Sitosterol, stigmasterol, (Cham. & Schltdl.) Steud. for hemorrhoids orto-benzoic acid, m-methoxy- Múlgura de Romero 1613 (SI) COS, MIS, SAL phydroxy-benzoic acid, phaeophitin a Spermacoce tenuior L. Leaf: antidiarrheal, for dysentery, No biological test No data Burkart (SI 11364) febrifuge CAT, JUJ, LRI, SAL, TUC RUTACEAE Balfourodendron Par not specified: odontalgic Wood: allergenic activity Dried heart-wood. Dl-Ribaline, riedelianum (Engl.) Engl. COS, MIS skimmianine: quinoline alkaloids. Guatambú blanco, guatambú, guatambú morotí, ibirá ñetí Gamerro 147 (SI) Esenbeckia febrifuga (A. Bark: febrifuge, aphrodisiac Stem: antiplasmodial activity Stem. Bergaptene, isopimpinellin, St.-Hil.) A. Juss. ex Mart. MI aurapten: coumarins; flindersiamine, Guatambumí, Ibirá-ovi-guazú kokusaginine, skimmiamine, g-fagarine, 295 Rodríguez 436 (SI) 1-hydroxy-3-methoxy-N- methylacridone: alkaloids; rutaevine: limonoid

296

Helietta apiculata Benth. Par not specified: antiparasitical Leaf: potentiate the CNS Leaf. Furoquinolines Tomo34(1-2):7-365.2009 Canela de venado, canela COS, MIS depressant effect of amarilla, ibirá obí, ibirá jhoví pentobarbital Rodríguez 15 (SI) Pilocarpus pennatifolius Dried leaf, decoction: against No biological test Stem. Pilocarpine: alkaloid Lem. diarrhea, to treat respiratory tract Stem + leaf essential oil. 2- Jaborandí, cutia, yaguarundí, infections, diuretic, diaphoretic, tridecanone, β-caryophyllene, 2- camba, canilla sialagogue pentadecanone, caryophyllene oxide, Cabrera 28636 (SI) Inflorescence: capillary tonic, germacrene D sialagogue Part not specified: odontalgic, abortive, ear disorders CHA, COS, FOR, MIS Zanthoxylum coco Gillies ex Bark + leaf: sudorific, diuretic, Aerial parts: antibacterial and Stem bark. Chelerythrine, berberine, Hook. & Arn. astringent antifungal activity fagarine II: alkaloids Coco, cocucho, cochucho, CAT, COR, JUJ, LRI, SAL, SLU, Part not specified. Furoquinolones, sauco hediondo TUC phenylethylamines, ortho-coupled Fagara coco (Gillies ex aporphines, ortho-coupled Hook. & Arn.) Engl. benzophenanthridines, para-coupled Subils et al. 3388 (CORD) benzophenanthridines, ortho-coupled protopines, para-coupled protopines, protoberberines Zanthoxylum fagara (L.) Sarg. Bark + leaf: sudorific, tonic, No biological test Trunk bark. Laurifoline, nitidine: Uña de gato, uña de tigre, lithotriptic, antirrheumatic, emetic, isoquinoline alkaloids cuentrillo, cu rutú-ra, m amica diuretic, odontalgic Part not specified. L- de cadela, temberatí, teta de Leaf: analgesic benzyltetrahydroisoquinolines, perra, tembetarí puitá, tembe- Spines: for alcoholism phenylethylamines, ortho-coupled

ratí colorado, temberatí mí BAI, CHA, COS, ERI, FOR, MIS, aporphines, ortho-coupled KURTZIANA Fagara hyemalis (A. St.-Hil.) SAL, SFE benzophenanthridines, para-coupled Engl. aphorphines, para-coupled Fagara pterota L. benzophenanthridines Krapovickas 15458 (SI)

Zanthoxylum petiolare A. Leaf , flowers, fruit: sialagogue, Leaf: anti-inflammatory, Dried bark. Chelerythrine, BARBOZA, G.E.etal.MedicinalfloraofArgentina St.-Hil. & Tul. sudorific, diuretic, stimulant analgesic and antimalarial magnoflowersine: isoquinoline alkaloid Cunatuna, naranjillo, sacha Fresh leaf: to cure or prevent acne activity Leaf. β-selinene, α-cyperone, (-) limón, temberatí, temberatí Part not specified: febrifuge, for (sub nom. Z. naranjillo) juniper camphor: sesquiterpenes; (+)- amarillo, temberatí guazú, conjunctivitis sesamin, (-) pluviatylol 4’-O-γ-γ- temberatí mí, temberatí CHA, COS, FOR, JUJ, MIS, SAL, dimethylallylether, (-) xanthoxylol 4’- morotí, temberatí saiyú SFE, TUC O-γ-γ-dimethylallylether, (+)piperitol Fagara naranjillo (Griseb.) 4’-O-γ-γ-dimethylallylether, (- Engl. )kinokinin, (-) hibalactone, (-) Joergensen 2585 (SI) methylpluviatolide, (-) kaerophyllin, (-) cubebin, (-) dimethoxy-3,4- dimethylenedioxy cubebin (sub nom. Z. naranjillo) Part not specified. L- benzyltetrahydroisoquinolines, ortho- coupled benzophenanthridines (sub nom. F. naranjillo) Zanthoxylum rhoifolium Dried bark, infusion: stimulant. Dried bark: uterine relaxation Dried root bark. Zanthoxyline: Lam. Part not specified: against tooth effect isoquinoline alkaloid Fagara rhoifolia (Lam.) Engl. ache, against earache, sialagogue, Dried root bark: antibacterial Dried stem. Lupeol, lupenone: Basuda, cuentrillo, curatú diaphoretic, diuretic, anthelmintic and antiyeast activity triterpenes; : flavanone morotí, amica de cadela, BAI, CHA , CO S, ERI, F OR, J UJ, Dried stem bark: antibacterial Dried stem bark. Rhoifoline A, B, ojo de pollo, temberatí, MIS, SAL, SFE, TUC activity nitidine,dihydro: 6-acetonyl, dihydro temberatí mí, teta de perra chelerythrine,: 6-acetonyl, iso Gamerro 159 (SI) corydine,: N-methyl, avicine,dihydro: 6-acetonyl, candicine, nitidine,6-oxy, nitidine,dihydro, magnoflowersine, zanthoxyline, tembetarine: isoquinoline alkaloids; skimmianine: quinoline alkaloid; lupeol: triterpene; sesamin: lignan Bark. Lupeol: triterpene; magnoflowersine: isoquinoline alkaloid Dried leaf. Lupeol: triterpene; imperatorin: coumarin; haplopine: quinoline alkaloid 297 Dried fruit. Imperatorin, aurapten,5'- hydroxy: coumarins

298 SALICACEAE Azara lanceolata Hook. f. Entire plant: medicinal Leaf + stem: antitumor activity No data Tomo34(1-2):7-365.2009 Corcolen Dried part not specified: for Cocucci 1405 (CORD) promotion of good health CHU, NEU, RNE Azara microphylla Hook. f. Part not specified: analgesic/ anti- No biological test No data Chin-chin inflammatory Correa 5739 (BAA) CHU, NEU, RNE Casearia sylvestris Sw. var. Leaf + bark: anti-inflammatory, Fresh bark + leaf: analgesic Dried leaf. Casearia clerodane I , II, III, sylvestris cicatrizant, febrifuge activity IV, V, VI casearin: diterpenes Burro caá, quillero, palo Bark, infusion: for diarrhea; Leaf: antiulcer, anti- Dried leaf + twigs. Casearvestrin A: rajador, guatatumba, rajador decoction: febrifuge inflammatory, and antitumor diterpene Arbo 7924 (CTES) Leaf, decoction: antivenin; to treat activity; protect cells against herpes, syphilis and snakebite DNA damage CHA, COS, ERI, FOR, JUJ, MIS, SAL Salix humboldtiana Willd. Bark stem: against influenza, Aerial parts: antibacterial Leaf. Flavonoids, coumarin, tannins Sauce colorado, sauce criollo, antirheumatic, antispamodic, activity sauce chileno, sauce isleño, sedative, febrifuge, astringent, sauce amargo dermatosis Subils 1279 (CORD) BAI, CAT, CHA, CHU, COR, COS, DFE, ERI, FOR, JUJ, LPA, MIS, NEU, RNE, SAL, SDE, SFE, SJU, TUC Xylosma venosa N.E. Br. Aerial parts: for sores in the No biological test No data Burkart 30956 (SI) mouth, against toothache CHA, COS, ERI, FOR, MIS, SFE SAMOLACEAE Samolus valerandi L. Entire plant, infusion: vulnerary, No biological test Fresh flower + leaf. Kaempferol: Carambola blanca, berro antiscorbutic flavonol

Subils 1150 (CORD) Leaf: antiscorbutic, vulnerary, for KURTZIANA otitis. Dried flowers, infusion: vulnerary. BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, RNE, SAL, SCR, SDE, SFE, SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina SANTALACEAE Acanthosyris falcata Griseb. Fruit: vulnerary, anti- No biological test No data Saucillo, Ibá-je-é, Ibá-hé, ivá- inflammatory, ophtalmic jee, sacha pera, sombra de Seed, ash: analgesic, ocular, toro hembra cicatrizant, antiseptic Martínez 468 (CORD) CHA, COR, COS, FOR, JUJ, SAL, SFE, TUC Jodina rhombifolia (Hook.. Leaf + bark: antidiarrheal, Plant: antibacterial, antioxidant, Seed oil. 9-octadecynoic acid (stearolic & Arn.) Reissek antidysenteric, anti-inflammatory, antineoplasic and anti- acid), trans-10-heptadecen-8-ynoic acid Quebracho flojo, peje, antitussive, abortive, hypotensive, inflammatory activity (pyrulic acid), 7-hydroxytrans- sombra de toro for sore throats, kidney stones or l(~heptadecen-8,ynoic acid, trans- Cocucci 124 (CORD) pain, stomach indisposition, 10,16-heptadecadien-8-ynoic acid, 7- articular and muscular pains hydroxy-trans-10,16-heptadecadien~- Leaf : against the alcoholism, ynoic acid, trans~ll~actadecen-~ynoic digestive, for carcinoma. acid (ximenynic acid), 8-hydroxy-trans- Fruit: antivenereous ll-octadecen-~ynoic acid, trans-ll,17- BAI, CAT, CHA, COR, COS, ERI, octadecadien-9-ynoic acid, 8-hydroxy- JUJ, LPA, MEN, RNE, SAL, SDE, trans-ll,17-octadecadien-9-ynoic acid, SFE, SJU, SLU, TUC 9-hydroxystearic acid, 9,10- epoxystearic acid: acetylenic fatty acids Leaf. Phenolic compounds, organic acids, tannins, flavonoids, steroids, gum, mucilague Aerial parts. Steroids, triterpenoids, alkaloids, coumarins, saponins Myoschilos oblongum Ruiz Leaf + root: digestive, tonic, Leaf + stem: antitumor activity Dried root. Docosan-1-ol-trans-para- & Pav. lithotriptic, emmenagogue coumarate : alkanol C5 or more Codo, coipú, codoipú CHU, NEU, RNE, SCR, TDF Boelcke 1650 (SI). Quinchamalium chilense Aerial parts: emmenagogue, Leaf + stem: cytotoxic ctivity Plant. glycosides Molina cicatrizant, for bruises, hepatic, Quinchamali intestinal Cocucci 2319 (CORD) CHU, JUJ, MEN, NEU, RNE, SCR 299

300 SAPINDACEAE Allophyllus edulis (A. St.- Leaf + stem: digestive, hepatic, Aerial parts: genotoxic activity Leaf + stem. Phenolic compounds; Tomo34(1-2):7-365.2009 Hil., A. Juss. & Cambess.) diuretic Leaf: hepatotoxic activities cyanogenetic glycosides; flavonoids; Radlk. Fruit: tonic, depurative, febrifuge, against CCl4 and galactosamine naphthoquinones; anthraquinones; Chalchal, coco, bacu, cocú, antirheumatic cytotoxicity alkaloids; steroids; triterpenoids coquy, jocú, kokú, comida de Part not specified: for skin Leaf. Schaftoside, vicenin-2, lucenin-2, paloma, frutilla, guacú, eruptions isovitexin 2"-O-rhamnoside, chichita BAI, CAT, CHA, COS, ERI, FOR, cerarvensin 2"-O-rhamnoside, vitexin Krapovickas 15931 (CTES) JUJ, MIS, SAL, SDE, SFE, TUC 2"-O-rhamnoside, isoorientin 2"-O- rhamnoside, orientin 2"-O-rhamnoside, saponarin; gallic acid, , 11-O- galloylbergenin, 3-O-rhamnosides; mollupentin 2"-O-rhamnoside: C- glycosylflavone Allophylus guaraniticus Part not specified: antidepressive No biological test No data (A.St.-Hil.) Radlk. COS, FOR, MIS Tapité, cocurá Ferrucci 444 (CTES) Cardiospermum halicaca- Dried aerial parts, infusion: for Dried aerial parts: anti- Plant. Saponin, quebrachitol, apigenin, bum L. var. halicacabum nervous diseases, chronic inflammatory activity proanthocyanidin and stigmosterol Amor en bolsa, globitos, bronchitis; tincture: for itching, Dried seed. Apigenin: flavone; globo, júpulo, munditos digestive, psoriasis campesterol: steroid Cantero et al. s.n. (RIOC 673) Leaf: antirheumatic, for chronic Decorticated seed. n -Eicosene bronchitis, stiffness of limbs and snakebite Unripe fresh leaf: analgesic Leaf + root, infusion: diuretic, diaphoretic, for amenorrhea BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, LRI, MIS, SAL, SDE, KURTZIANA SFE, SJU, SLU, TUC Cupania vernalis Cambess. Root: diuretic, diaphoretic, Dried leaf: molluscicidal Seed. Fatty acids Ramo, guayabo colorado, narcotic activity Plant. Vernanolide: diterpene yaguaratay, jacarandá-mí, CHA, COR, COS, ERI, FOR, JUJ, corpus, camoatá MIS, SAL, TUC Ferrucci 200 (CTES, MERL)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Diatenopteryx sorbifolia Part not specified: to treat hernia No biological test Timber. 3β,6β-dihydroxy-21αH-24- Radlk. COS, JUJ, MIS, SAL norhopa-4(23),22(29)-diene, 3β,5β- Suiquillo dihydroxy-6β-[(4- María preta, ibirá-pí-hú, hydroxybenzoyl)oxy]-21αH-24- saiquillo Vanni 3111 (BAB, norhopa-4(23),22(29)-diene: hopene CTES, LIL) derivatives; cleomiscosin B, 5,6- dimethoxy-7-hydroxycoumarin (umckalin) Dodonaea viscosa Jacq. Leaf: analgesic, anti-inflammatory, Leaf: anesthetic, smooth muscle Leaf. Aliarin, dodonic acid, hautriwaic Chamisa, chamizo, chilca, antiviral, spasmolytic, laxative, relaxant, antibacterial, acid, dodonosides A and B, viscosol, chilca colorada, chilca del antimicrobial and hypotensive, to antifungal, anti-inflammatory, stigmosterol, isorhamnetin, penduletin, monte treat rheumatism, gout, and anti-ulcerogenic, quercetin, doviscogenin, Ahumada 8528 (CTES, SI) hemorrhoids, fractures and anti-ascariasis, anthelmintic, Aerial parts. Saponins, sterols, tannins, snakebites, for headache, cardiac depressant, uterine triterpenoids stomachache, ulcers relaxation hypotensive, and BAI, ERI, JUJ, SAL, SFE, TUC vasoconstrictor activity Paullinia elegans Cambess. Medicinal Leaf: antimicrobial and Seed oil. Triglycerides, cyanolipid Isipó, caí-escalera-ra, isopó- CHA, COS, ERI, FOR, MIS, SFE protozoal activity morotí, ojo de muñeca Barboza 1674 (CORD) Paullinia pinnata L. Bark, leaf + flowers: narcotic, Dried aerial parts: antimalarial Dried leaf. Diosmetin-7-O-(2''-O-β-D- Isipo vulnerary. and antibacterial activity apiofuranosyl-6''-acetyl-β-D- Arbo 1578 (CORD) Leaf, infusion: to produce glucopyranoside): flavone abortion, for rabies, aphrodisiac CHA, COS, FOR, SFE Sapindus saponaria L. Root: tonic, hemostatic Dried fruit: antiulcer activity Dried stem. Luteolin: flavone Palo jabón, casita-rá, quillai. Fruit: toxic, narcotic, soporific, for Dried seed. α-amyrin: triterpene iba-ro, yuquití epilepsy Martínez 297 (CORD) Seed: astringent CAT, CHA, COS, FOR, MIS, SAL, SFE Serjania caracasana (Jacq.) Leaf: stomach pain Leaf + stem: antioxidant activity Aerial parts. Serjanosides Willd. CHA, COS, FOR, JUJ, MIS, SAL,

Isipó-y, isipó de agua SFE 301 Arenas 960 (CORD)

302 Serjania marginata Casar. Part not specified: narcotic No biological test No data Tomo34(1-2):7-365.2009 Timbó bravo FOR, JUJ, SAL, SDE, TUC Schinini 19538 (CORD) Urvillea chacoënsis Hunz. Leaf: stomach pain No biological test Seed oil. Fatty acids Gop gop CAT, CHA, COR, COS, FOR, Hunziker 24612 (CORD) JUJ, LRI, SAL, SDE, SJU, TUC SAPOTACEAE Chrysophyllum gonocar- Part not specified: antidiarrheal No biological test Leaf + stem. Alkaloids pum (Mart. & Eichler) Engl. CHA, COS, ERI, FOR, JUJ, MIS, Agauaí, aguay, aguaí-saiyú, SAL, SFE, TUC aguaí guasú, aguaí amarillo guasú Cerana 881 (CORD) Chrysophyllum Leaf + leafy stem: expectorant Dried leaf + stem: antiviral , Leaf. α-amirin, gallic acid, myricitrin, marginatum (Hook. & Arn.) CAT, CHA, COR, COS, ERI, and cytotoxic activity quercitrin, (-)-epigallocatechin and (-)- Radlk. subsp. marginatum FOR, JUJ, MIS, SAL, SFE, TUC Leaf: antioxidant activity epigallocatechin-3-O-gallate Lanza blanca, vasuriña, picazú- renviú, carapún, olivo-rà, ivîrá- cambî, basuriña, blanquillo colorado, mata negra Deginani 1181 (SI) Pouteria gardneriana (A. Part not specified: vulnerary No biological test No data DC.) Radlk. CHA, COS, ERI, FOR, MIS, SFE Aguay, aguaí, aguí-saiyú, aguí-guazú, aguaja, mata ojos colorado Joergensen 2100 (LIL, SI).

Pouteria salicifolia (Spreng.) Leaf: vulnerary No biological test Leaf. Terpenoids, saponins, flavonoids, KURTZIANA Radlk. BAI, COS, ERI, MIS glycosides Mata ojo, mal de ojos, aguay, marcela, aguaí-guasú, aguaí, sarandi guasú, cedrillo, laurel Correa 5390 (BAA, BAB, SI)

Sideroxylon obtusifolium Bark: anti-inflammatory, anti- Dried branches + fruit: radical Fruit. Citric acid BARBOZA, G.E.etal.MedicinalfloraofArgentina (Roem. & Schult.) T. D. ulcer, analgesic; decoction: scavenging effect Penn. analgesic, pectoral Cabo de lanza, horco molle, Dried branches: for diabetes and molle negro, guaraniná, lanza ovarian inflammation colorada, guayaîviraí Part not specified: aphrodisiac Luti 1321 (CORD) CHA, COR, COS, ERI, FOR, JUJ, MIS, SAL, SDE, SFE, TUC BAI, COS, ERI, MIS SIMAROUBACEAE Alvaradoa subovata Cronquist Bark: for pruritis No biological test No data Pichi blanco, sacha ruda, chu- Wood: tonic, stomachic quisaca, pichi, palo hormiga JUJ, SAL, TUC Hunziker 1226 (CORD) Castela coccinea Griseb. Root: antidysenteric Branch, leaf + bark: No data Espada, granadillo, melonci- Cortex: for urinary affections antimalarial activity llo, mistol de chivo, mistol CAT, CHA, COR, COS, FOR, Cortex: antioxidant and del zorro, molle colorado, JUJ, LRI, SAL, SDE, SFE, TUC cytotoxic activity molle negro, sacha melón, sacha meloncillo Hunziker 9267 (CORD) Castela tweedii Planch. Bark: against diarrhea Root bark: antiviral activity Root bark. Castelanone: Granadillo, meloncillo, molle Leaf: for stomachache nortriterpenoid (quassane) sigle, sacha melón BAI, CAT, COS, ERI, MIS, SFE, Rodríguez 514 (SI) TUC Picrasma crenata (Vell.) Dried w ood, decoction: to treat Wood (without bark): anti- Wood. Benzoquinone,16-β-O- Engl. diabetes mellitus, antimalarial, to ulcer and blood glucose methylneoquassin and 16-β-O- Palo amargo, quina amarga control stomachic parasites lowering effect ethylneoquassin, coniferyl aldehyde, Aeschrion crenata Vell. Part not specified: tonic, Aerial parts: weak antimalarial coniferin, cantin-6-one, 4,5- Tressens 6473 (SI) antisyphylitic, emmenagogue, activity dimethoxycantin- febrifuge, antidiarrheal, antacid, 6-one and (+)-neo-olivil, vermicide, odontalgic, maturating, dihydronorneoquassim, paraine, for scabies isoparaine, 12-norquassine, α- MIS neoquassine, β-neoquassine, quassine; 1-carbomethoxy-β-carboline, crenatine (1-ethyl-4-methoxy-β-carboline), 303 crenatidine (1-ethyl-4,8-dimethoxy-β- carboline): alkaloids

Simaba glabra Engl. Part not specified: bitter tonic, No biological test No data 304

Molfino s.n. (BAF) febrifuge Tomo34(1-2):7-365.2009 MIS SOLANACEAE Brugmansia suaveolens Aerial parts: hypnotic, analgesic Extracts: smooth muscle Aerial parts. Scopolamine, hyoscyamine, (Humb. & Bonpl. ex Willd.) Fresh leaf: hallucinogen; relaxant activity hygrine, cuscohygrine: tropane alkaloids Bercht. & J. Presl decoction: antirheumatic, emollient Flowers: antinociceptive effects Root. Tropine, pseudotropine, scopoline, Floripón, floripondio Part not specified: to prevent scopine, 3α-acetoxy tropane, 3-acetoxy-6- Múlgura de Romero 1764 insomnia, for hallucinogenic effect hydroxytropane, 3α-tigloyloxytropane, (SI) MIS cuscohygrine, 3-hydroxy-6-(2-methyl butyryloxy)-tropane, 3-tigloyloxy-6- hydroxytropane, 3-hydroxy-6- tigloyloxytropane, apoatropine, 3- tigloyloxy-6-(2-methylbutyryloxy)- tropane, aposcopolamine, hyoscyamine, 3α,6β-ditigloyloxytropane, 7β- hydroxyhyoscyamine, 6β- hydroxyhyoscyamine: tropane alkaloids Brunfelsia uniflora (Pohl) Plant: alexipharmic Plant: anti-inflammatory and Aerial parts. Aesculetin, α-ionone, α- D. Don Leaf: for arthritis and rheumatism analgesic, anticoagulant, terpineol, benzyl benzoate, benzyl Jazmín del Paraguay, Root: diuretic, purgative, antimutagenic, and salicylate, β-bisabolene, β-cyclocitral, mercurio vegetal, manacá, abortifacient, antisyphylitic, antispasmodic activity; central brunfelsene, β-damascenone, β- manacán, chiric sanango, antiseptic, emmenagogue, nervous system depressant; eudesmol, β-safran al, brunfelsamidine, chuchuwasha, manaka, febrifuge, antirheumatic, for febrifuge; refrigerant (lowers elemol, 2-ethylfuran, farnesol, geraniol, managá caa, gambá, gerataca, venereal diseases, back pain, body temperature) activity geranyl hopeanine, ionones, isobutyl chuchuwasha, geratacaca, common colds, bronchitis, lung salicylate, lavandulal, limonene, linalool, santa maria, umburapuama disease and tuberculosis, snakebite, linoleic acid, linolenic acid, manaceine, Zuloaga 7723 (SI) topical pain-reliever, and as an manacine, mandragorine, methylfurans, enema for kidney disorders and methylanisoles, myrcene, myristic acid, n- ulcers; decoction: to treat arthritis, decane, n-heneicosane, n-heptadecane, n- rheumatism, colds and flu, uterine heptane, n-hexadecane, nerolidol, n- nonadecane, nonanes, n-octane, n- pain and cramps KURTZIANA JUJ, SAL pentacosane, n-pentadecane, neophytadiene, n-tricosane, ocimene, pentadecanoic acid, palmitic acid, pinoresinols, scopoletin, scopolin, terpinolene Root. Coumarins, alkaloids, lignans and sapogenins; manaceine and manacine, scopoletin, aesculetin

Capsicum baccatum L. var. Fruit: rubefacient, stomachic, for Fruit: antibacterial activity Fruit. , dihydrocapsaicin: BARBOZA, G.E.etal.MedicinalfloraofArgentina baccatum diabetes sub nom. C. baccatum alkaloids Ají del campo, ají quitucho, CHA, COS, JUJ, MIS, SAL, TUC ají cumbarí, ají del monte Barboza 927 (CORD) Capsicum chacoënse Hunz. Fruit: hepatic, rubefacient, No biological test Fruit. Capsaicin: alkaloid Ají cumbari, ají del campo, antirheumatic, antidiarrheal, ají del monte, picante del anthelmintic, to relieve the campo, putaparió stomach-ache, digestive; powder: Subils et al. 1229 (CORD) for gastrointestinal pains, vermifuge, stomachic CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, SAL, SDE, SFE, SJU, SLU, TUC Cestrum euanthes Schltdl. Bark: cathartic, increases No biological test Fresh leaf. Chlorogenic acid, caffeoyl- Duraznillo negro sweating, tempering, febrifugal glucose: phenylpropanoid Hunziker 2588 (CORD) BAI, COS, ERI, MIS Cestrum parqui L’Hér. Entire plant: hepatoxic Dried aerial parts: β- Dried leaf + stem. Solasodine, solasonine: Duraznillo, duraznillo negro, Dried aerial parts: febrifuge, for glucuronidase inhibition; anti- steroidal alkaloid; tigogenin, hediondilla, palque, palqui, frozen limbs, and to treat inflammatory and antifungal monohydroxisapogenin, parquigenin, duraznillo negro hediondo, inflammatory tumors activity gitogenin, digitogenin, isonuatigenin, fernadillo, flor del carnaval, Root bark: antispasmodic, Flowers: antifungal activity : saponins and steroidal hediondilla negra, hediondilla purgative sapogenins; ursolic acid: triterpene del campo, karalawa, mata Root: digestive Leaf. 2-p-hydroxyphenylethanol, p- caballos, palqui amarillo, Bark + leaf: febrifuge, diaphoretic hydroxyphenil-hydroxymethyl-ketone: palqui negro, rama verde Leaf: antispamodic, anti- phenylethanoids; methyl benzoate, Subils 3384 (CORD) haemorrhoidal, purgative, benzaldehyde; N-(p- refrescant; for skin diseases carboxymethylphenyl)-p- (itching, welts) hydroxybenzamide; bibenzofuran type Leaf + flowers: for treating sesquilignan, 2(3H)-furanone type wounds externally, antiseptic, norlignan, “head-to head” linked 4.0.4’- abluent type neolignan; parquin, BAI, CAT, CHA, COR, COS, ERI, carboxiparquin: kaurene glycosides; FOR, JUJ, LR I, MEN, MIS, RNE, triterpenoid saponins; megastigmenes, nor SAL, SDE, SFE, SJU, SLU, TUC megastigmadienes: isoprenoids 305 Fruit. Digitogenin, tigogenin, digalogenin: steroidal saponins

306

Cestrum strigilatum Ruiz & Stem, leaf + flowers: to control No biological test No data Tomo34(1-2):7-365.2009 Pav. and regulate menstrual cycle Jazmín de noche, naranjillo CHA, COS, FOR, JUJ, MIS, SAL, Hunziker 20669 (CORD) SDE, SFE, TUC Fabiana densa J. Rémy Part not specified: in baths for No biological test No data Tola, checal, chillán, chiyán, indigested children tola cecal, tola chacal, tola CAT, JUJ, SAL, TUC checal, tola chillán, tola delgada, tola toque, tolilla, tome Hunziker 24884 (CORD) Fabiana imbricata Ruiz & Dried entire plant, infusion: Dried aerial parts: ˜- Dried aerial parts. 4-hydroxy Pav. diuretic, cholagogue, digestive, to glucuronidase inhibition; acetophenone: benzenoid; amorph-4- Palo piche, romero pichi, treat tumors gastroprotective and diuretic en-11-ol, fabianine: tetrahydroquinoline piche, pichi Dried wood, infusion: diuretic activity alkaloid; scopoletin: hydroxycoumarin; Hunziker 20151 (CORD) Part not specified: anticatarrhal, Dried leaf + stem: antibacterial oleanolic acid: triterpene balsamic activity Aerial parts + in vitro cultures. CHU, MEN, NEU, RNE, SJU Oleanolic acid, rutin, chlorogenic acid, scopoletin Fabiana peckii Niederl. Leaf: antitussive, for colds No biological test No data Barboza 1179 (CORD) BAI, CHU, LPA, LRI, MEN, NEU, RNE, SJU Grabowskia duplicata Arn. Leaf: cicatrizant No biological test Dried leaf + stem. Scopoletin: Estampa, matorral, matorro BAI, CAT, CHA, COR, COS, ERI, coumarin; negro, tala de burro, yuqui-ra FOR, LPA, SDE, SFE, SLU, TUC Leaf + Stem. Alkaloids Di Fulvio 372 (CORD) Grabowskia obtusa Arn. Part not specified: vulnerary No biological test No data

Tulisquín, uña del tigre, oreja CAT, COR, LRI, MEN, NEU, KURTZIANA de gato, fallampe, jayampe, SDE, SJU, SLU albaricoquillo, albaricoque Hunziker 25523 (CORD)

Jaborosa caulescens var. Part not specified: cholalogue, Dried leaf + root + stem: Aerial parts. Jaborosalactone 39 BARBOZA, G.E.etal.MedicinalfloraofArgentina bipinnatifida (Dunal) Reiche hemostatic antibacterial activity [(20R,22R)-5β,6β:12α,21-diepoxy- Yerba sapo CAT, JUJ, LRI, MEN, SAL, SJU 12β,17β-dihydroxy-1-oxowith-24-en- Barboza 237 (CORD) 26,22-olide], jaborosalactone 40 [(22S,23R)-12α,22-epoxy-12β,17β,21- trihydroxy-1-oxowitha-2,5,24-trien- 26,23-olide], jaborosalactone 41 [(22S,23S)-12α,22-epoxy-12β,17β,21- trihydroxy-1-oxowitha-2,5,24-trien- 26,23-olide], jaborosalactone 42 [(22S,23R)-5α-chloro-12α,22-epoxy- 6β,12β,17β-trihydroxy-1-oxowitha- 2,24-dien-26,23-olide], 12-O-Ethyl- jaborosalactone 42 [(22S,23R)-5α- chloro-12α,22-epoxy-12β-ethoxy- 6β,17β-trihydroxy-1-oxowitha-2,24- dien-26,23-olide]: withanolides Jaborosa integrifolia Lam. Leaf: analgesic No biological test Plant. Jaborosalactone A, B, C: Flores d e sapo, f lor de sapo , Leaf and flowers: disinfectant, withanolides lengua de vaca abluent, vulnerary Barboza 122 (CORD) Root: ansiolitic BAI, CHA, COR, COS, DFE, ERI, FOR, JUJ, SAL, SFE Jaborosa runcinata Lam. Root: toxic, narcotic No biological test Dried aerial parts. Jaborosalactone 1, Flores de sapo Dried leaf, infusion: sedative, 2, 3, 4, 5, 6: steroids Tivano 560 (CORD) anesthetic Dried leaf. Alkaloids BAI, COR, ERI, SFE Lycianthes asarifolia (Kunth Leaf bud: for boils No biological test No data & Bouché) Bitter CHA, FOR, JUJ, MIS, SAL, SFE, Burkart 14971 (LIL) TUC Lycium cestroides Schltdl. Leaf: stomachic, rubefacient, No biological test Dried leaf. Histamine, cis-and trans- Calchal, chile, chili, comida earache N-α-cinnamoylhistamine, N-1-methyl de víbora, tala de calchal, tala Part not specified: antidiarrheal derivatives de rundún, talilla BAI, CAT, CHA, COR, COS, JUJ, Bernardello & Ari za Espi nar LRI, SAL, SDE, SFE, SJU, SLU, 307 156 (CORD) TUC

308 Nicandra physalodes (L.) Dried entire plant, decoction: Dried entire plant: cytotoxic Root. Hygrine, cuscohygrine, Gaertn. pediculocide, diuretic and antimicrobial activity hygroline, norhygrine: pyrrolidine Tomo34(1-2):7-365.2009 Farolito, margarita Leaf: insecticide alkaloids Novara 11021 (CORD) JUJ, SAL, TUC Plant. Loliolide, (-): sesquiterpene; calystegine B1: tropane alkaloid; ecdysteroids; nicandrenone: withanolides, Nicotiana glauca Graham Leaf: for treating wounds externally, Dried aerial parts: antiyeast Fresh entire plant. Anabasine, Palán-palán, belén-belén, maturating, vulnerary, anti- activity; teratogenic effect anabatine, nicotine, nornicotine, N- palancho, karalawa, árbol inflammatory, anti-haemorrhoidal, Dried fruit + leaf + stem: acetylnornicotine: pyridyl-pyrrolidine tonto antirheumatic, for frozen limbs, antibacterial activity alkaloids Cocucci 1430 (CORD) headache and general body pains Leaf. Cholesterol, campesterol, Dried bark: for rheumatism stigmasterol, β-sitosterol: sterols Flowers: antiasthmatic Root: anabasine CAT, FOR, JUJ, LRI, SAL, TUC Root cultures: nicotinic acid Nicotiana longiflora Cav. Aerial parts: for frozen limbs Plant: cytotoxic and antifungal Leaf. Anabasine, nicotine, nornicotine, Flor de sapo, Flor de tarde, Leaf: anti-inflammatory, activity anatabine, N-acetylnornicotine: pyridyl- flor de sapo, tabaco del cam- cicatrizant pyrrolidine alkaloids po, tardilla, coro, sacha BAI, CAT, CHA, COR, COS, Vegetative organs + flowers. α and β- tabaco DFE, ERI, F OR, J UJ, LPA, LR I, pinene, camphene, sabinene, β-myrcene, Cocucci et al. 1418 (CORD) MEN, MIS, SAL, SDE, SFE, TUC limonene, E-β-ocimene, α-terpinolene: monoterpenes; 1,8-cineole, linalool: oxygenated monoterpenoids; β- caryophyllene, E-β-farnesene, α-humulene: sesquiterpenes; caryophyllene oxide: oxygenated sesquiterpenoids; dimethylcyclohexanone isomer; fatty-acid derived esters; 2-methylbutylnitrile, nitro- 2-methylbutane, isobutyraldoxime, 2-

methylbutyloxime: nitrogenous KURTZIANA compounds Nicotiana undulata Ruiz & Part not specified: against No biological test Leaf. Anabasine, nicotine, nornicotine, Pav. external traumatisms N-acetylnornicotine: pyridyl- Quitatabaco, ca masaire, mata JUJ, SAL pyrrolidine alkaloids tabaco, tabaco del campo Leaf + root. Anatabine Negritto 369 (CORD)

BARBOZA, G.E.etal.MedicinalfloraofArgentina Nierembergia lineariifolia Leaf: cicatrizant, stomachic Aerial parts: cytotoxic activity Entire plant. 20R,22R)- Graham CAT, CHA, COR, COS, ERI, JUJ, 2β,3β,11α,14α,20,22-hexahydroxy-5β- Chucho violeta, chuchu, LPA, MIS, SAL, SDE, SLU, TUC cholestan-6-one (7,8-dihydroajugasterone chuscho, matacaballo C or 7,8-dihydro-11α-hydroxyponasterone Nierembergia hippomanica A): ecdysteroid-like Miers polyhydroxyketosterol; hygrine, Di Fulvio 356 (CORD) norhygrine: pyrrolidine alkaloid; 3α- tigloyloxytropane: tropane alkaloid; brunfelsamidine: pyrrole alkaloid; ecdysterone; quercetin 3-O-β-D- galactopyranoside; D-mannitol; choline; tigloidine; β-phenylethylamine, tyramine and its N-methyl derivatives; ursolic acid, isomer of oleanolic acid Petunia axillaris (Lam.) Leaf: narcotic No biological test Leaf. Orthoester-type petuniasterones Britton, Stern & Poggenb. BAI, LPA, RNE Flowers. Benzenoids Coroyuyo, tabaco indio, tabaquillo Lorentz 306 (CORD) Physalis angulata L. Dried entire plant, decoction: Dried aerial parts: Dried entire plant. Withangulatin A: Tomatillo febrifuge; infusion: for gonorrhea, antitrypanosomal, steroid Barboza 997 (CORD) antipyretic, antitumor, diuretic, antimycobacterial, and Dried aerial parts. Withaferin A-type vulnerary, for malaria, asthma, cytotoxic activity physagulins H-K, L-N: withanolides; N- hepatitis, dermatitis and Root: genotoxic effect methylpyrrolidinylhygrine rheumatism Stem. Physalin D: steroid Root, infusion: for malaria, diuretic Fresh leaf + stem. Physalins (A, B, D Leaf, infusion: for asthma, anti- and F) and glycosides (myricetin-3-O- inflammatory, diuretic neohesperidoside) Dried fruit, infusion: for Dried fruit. Acetyl choline,: alkaloid- postpartum infection misc; chlorogenic acid: CHA, COS, ERI, FOR, JUJ, MIS, phenylpropanoid; myricetin-3-O- SAL, SFE, TUC neohesperidoside: flavonols

Physalis pubescens L. var. Root: rheumatic pain No biological test Aerial part. Physapubescin: ergostane- pubescens CHA, COS, FOR, JUJ, MIS, SAL, type steroid; hygrine, N- 309 Barboza 465 (CORD) SFE, TUC methylpyrrolidinylhygrine

310 Physalis viscosa L. Entire plant: diuretic, litolithic, Plant: antibacterial activity Aerial parts. 20-ketopregnane with its Carambú, huevo de gallo, anodyne, febrifuge A and B rings, 4 β-hydroxywithanolide Tomo34(1-2):7-365.2009 quillo, camambú, pocote del Leaf: for treating wounds externally E and withaphysanolide: withanolides campo, farolito Fruit: laxative Flower + stem. Physaloside A Physalis mendocina Phil. BAI, CAT, CHA, COR, COS, ERI, Dried stem. Physaloside A: acylated Hunziker 17381 (CORD) FOR, JUJ, LPA, LRI, MEN, MIS, sucrose ester NEU, RNE, SAL, SDE, SFE, SJU, Root. 4 β-hydroxywithanolide E, SLU, TUC withanolide D: withanolides Salpichroa origanifolia Leaf: narcotic, sedative; decoction: Plant: anti-inflammatory and Fresh leaf + stem. Salpichrolide A, C, (Lam.) Baill. for skin mycosis antibacterial activity G, J, K, L, M, N: withanolides; hygrine, Chumisquera, huevito de Root: for treating wounds Leaf + fruit: cytotoxic activity cuscohygrine gallo, meloncillo, uva, uvilla, externally, abluent uvita del campo Fruit: diuretic Cocucci 122 (CORD) BAI, CAT, CHA, COR, COS, DFE, ERI, FOR, JUJ, LRI, RNE, SAL, SLU, TUC Solanum aloysiifolium Part not specified: antimycotic, No biological test No data Dunal febrifuge Cabrera 34121 (SI) CAT, JUJ, LRI, SAL, SDE, TUC Solanum americanum Mill. Entire plant, infusion: topically Leaf: antitrypanosomal, and Entire plant. Solasodine: steroidal Arachichú, Hierba mora, for eye problems; internally to gain antimicrobial activity alkaloid yerba mora, Erva de Santa weight Leaf. Solasonine, solasodine: steroidal Maria Leaf: dermatomucosal infections alkaloids Barboza et al. 994 (CORD) dysentery (amebiasis), for Fruit. Diosgenin: steroidal sapogenin; leucorrhea and vaginitis solasodine: steroidal alkaloid; petanin, (trichomoniasis) delphanin: anthocyanins CHA, COS, MIS Solanum amygdalifolium Part not specified: medicinal No biological test Dried aerial parts. Solasonine: Steud. BAI, CAT, CHA, COR, COS, glycoalkaloid; foliumin A (22S, 23R,

Jazmín de Córdoba, amor DFE, ERI, FOR, JUJ, MEN, MIS, 25R)-3 β,15α,23-trihydroxyspirost-5- KURTZIANA porteño, duraznillo RNE, SAL, SDE, SFE, SJU, SLU, en-26-one 3-O-{α-L-rhamnopyranosyl- enredadera, jazmín azul TUC (1→2)-[α-L-rhamnopyranosyl-(1→4)]- Barboza 1566 (CORD) β-D-glucopyranoside}: spirosten δ- lactone saponin

BARBOZA, G.E.etal.MedicinalfloraofArgentina Solanum argentinum Bitter Aerial parts: febrifuge, toothache Leaf: antimalarial activity Seed oil. 5-dehydro avenasterol: & Lillo Root: antivenereous; decoction: campesterol: sterols Afata, hediondillo del monte, antisyphylitic hediondilla, duraznillo CAT, CHA, COR, COS, FOR, blanco, cabra yuyo, JUJ, LRI, SAL, SDE, SFE, TUC duraznillo Subils 421 (CORD) Solanum aridum Morong Fruit: for treating wounds No biological test No data Comida de víbora, melón del externally, antifungal, maturating campo, pocote, pocotillo, Fruit, powder: for treating boils tutía, meloncillo CAT, CHA, COS, FOR, JUJ, SAL, Solanum conditum C.V. Morton SDE, TUC Hunziker 8566 (CORD) Solanum betaceum Cav. Fruit: diuretic, digestive, against Fruit: free radical scavenging Aerial parts. Calystegine B1 Tomate del monte, tomate de hepatic affections effect Root. Solamine, 4N, 4’N- árbol JUJ, SAL, SDE, TUC bis(dimethylamino)-dibutylamine, Cyphomandra betacea (Cav.) solacaproine Sendtn. Fresh fruit. Benzoic acid: benzenoid; Barboza 1073 (CORD) callistephin: flavonoid; solasodine, tomatidenol: alkaloids; β-cryptoxanthin [(3R)-β,β-caroten-3-ol] Fruit pulp essential oil. 3-hydroxy butanoic acid: ethyl ester:

Solanum chenopodioides Aerial parts: ophtalmic No biological test Dried root. Tigogenin: sapogenin Lam. Dried leaf, infusion: cicatrizant, (sub nom. S. sublobatum) Hierba mora, yerba mora, laxative yerba buena (sub nom. S. sublobatum) Solanum sublobatum Willd. BAI, COR, ERI, NEU, RNE, SFE Hunziker 6872 (CORD) Solanum crispum Ruiz & Stem: febrifuge, antitussive Aerial parts: antiviral, Aerial parts. Scopoletin, β-sitosterol 3- Pav. Part not specified: gynecological, antipyretic, and O-β-D-glucoside Natre, natri, natren, natran obstetric antiinflammatory activity Solanum ligustrinum S. ligustrinum Lodd. MEN, NEU, RNE (sub nom. ) 311 Chiapella 1657 (CORD)

312 Solanum elaeagnifolium Dried aerial parts, infusion: for Dried aerial parts: cytotoxic Dried aerial parts. Astragalin: Cav. infections activity; gastroprotective effect flavonol; kaempferol 3β-D-(6’’-O-cis- Tomo34(1-2):7-365.2009 Granadillo, quillo, meloncillo Leaf + stem: diuretic cinnamoyl) glucoside, kaempferol, del campo, meloncillo de Fruit: for treating wounds kaempferol 3-O-glucoside: flavonoids olor, tutía enano, pocotillo, externally, abluent, antifungal Leaf. Cholecalciferol (vitamin D3 ) revienta caballo Root: antivenin Fruit. Solamargine: steroid alkaloid Hunziker 17347 (CORD) BAI, CAT, CHA, COR, COS, Seed. Solasodine: steroid alkaloid DFE, ERI, FOR, JUJ, LPA, LRI, MEN, NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC Solanum glaucophyllum Desf. Leaf + stem: emetic, purgative, Entire plant: calcinogenic Leaf. Arbutin: benzenoid; avicularin: Duraznillo, duraznillo blanco, diaphoretic, antirheumatic activity flavonol; calcitriol: steroid; 17β- duraznillo hediondo, varilla, Leaf: vulnerary, maturating ; cholecalciferol (vitamin D3 ), enteque-seco, varita, Stem, ash: analgesic 25-hydroxycholecalciferol, 1 α,25- duraznilo del agua Fruit: ophtalmic dihydroxyvitamin D3 Stuckert 23201 (CORD) BAI, CHA, COR, COS, ERI, FOR, MIS, SAL, SFE, TUC Solanum granulosum- Leaf: topic anti-inflammatory; No biological test Aerial parts. Papyriogenine A, B, C ; leprosum Dunal fumigant against head lice papyrioside L-II, propapyriogenines A1, Fumo bravo, fumito, cambará, Fruits: calmative (headaches and A2, 11-dehidro-propapyriogenine A2, lata de pobre, suncho blanco, ulcers) 16-episaicogenine tabaquillo, palo blanco, tabaco BAI, CHA, COS, ERI, FOR, MIS, Ripe fruits. Granulosain I: cysteine cimarrón, ambay SAL, SFE protease Barboza 365 (CORD) Solanum hieronymi Kuntze Fruit: for treating wounds No biological test No data Pocota, pocote, pocotillo externally, antifungal, maturating Cosa 268 (CORD) CAT, COR, COS, ERI, FOR, JUJ, LRI, SAL, SDE, SJU, SLU, TUC Solanum mauritianum Scop. Dried entire plant, infusion: to Dried leaf: cyclooxygenase 1 Leaf. Solasodine: steroid alkaloid Krapovickas et al. 25231 treat bronchial asthma inhibition KURTZIANA (CTES) Flower + root: antibiotic, bronchial tube infection Fruit + leaf: calmative, anti- inflammatory BAI, CTES

Solanum nigrescens M. Medicinal No biological test No data Martens & Galeotti BAI, CHA, COS, ERI, FOR, JUJ, BARBOZA, G.E.etal.MedicinalfloraofArgentina Solanum pilcomayense MIS, SFE, TUC Morong Krapovickas 22192 (CTES) Solanum palinacanthum Leaf: heart pain No biological test No data Dunal CAT, CHA, COR, COS, FOR, Tutiá JUJ, MIS, SAL, SDE, SFE, SLU, Ariza Espinar 3445 (CORD) TUC Solanum palitans C.V. Medicinal No biological test No data Morton BAI, CAT, COR, JUJ, SAL, TUC Ñusco Hunziker 21928 (CORD) Solanum pseudocapsicum L. Leaf: digestive, astringent Entire plant: hypotensive Dried aerial parts. Solacapine, Revienta caballo, sacha Root + leaf: antimicrobial activity episolacapine, isosolacapine, 7β- hediondilla Fruit: sedative, toxic Fresh leaf: hepatoprotective hydroxy-0-methyl-solanocapsine, Solanum tucumanense BAI, CAT, CHA, COR, COS, ERI, activity solacasine,solanocapsine: steroid Griseb. FOR, JUJ, LRI, MIS, RNE, SAL, Fruit: toxic effect, cytotoxic alkaloids; solacaproine: alkaloid Zygadlo 119 (CORD) SFE, SLU, TUC activity Dried leaf. Chlorogenic acid: phenylpropanoid Root bark. Solateinemine Dried fruit. Diosgenin: sapogenin; alkaloids Solanum sisymbriifolium Entire plant: narcotic Dried root: hypotensive activity Leaf + stem. Cilistepoxide, cilistadiol: Lam. Dried branch + leaf, decoction: to Branch + leaf: antibacterial withanolides Espina colorada, pocote, vila treat respiratory tract infections activity Dried root. Solacaproine: alkaloid; vila, pocotillo, revienta Root: diuretic, hypotensive, solasodine: steroid alkaloid; caballo, tomate del campo, abortifacient, antisyphilitic, [(25S)]nuatigenin: steroidal sapogenin tutía digestive, hepatic, antilithic Dried fruit. Carpesterol: triterpene; Ariza Espinar 3224 (CORD) Leaf and root: hepatic, cuscohygrine: alkaloid; sisymbrifolin: antinephritic benzofuran type neolignan Leaf: for treating wounds externally, febrifuge, analgesic, blood depurative; decoction: to treat wounds and grazes Flowers: antitussive

Fruit: laxative 313 BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SLU, TUC

314 Solanum stuckertii Bitter Medicinal No biological test Fresh flower essential oil. 2-4- Comida de víbora, duraznillo CAT, COR, JUJ, LRI, SAL, SDE, dimethyl acetophenone: benzenoid; β- Tomo34(1-2):7-365.2009 macho SLU, TUC elemene: sesquiterpene Hunziker 25325 (CORD) Solanum trichoneuron Lillo Medicinal No biological test No data Hediondilla, naranjillo, JUJ, SAL, TUC hediondillo grande, hediondillo del monte Subils 3529 (CORD) Solanum tripartitum Dunal Entire plant: ophtalmic, Entire plant: cytotoxic activity Entire plant. Solapalmitenine, Ñusco, tomatillo refrigerant solapalmitine: fatty acid amides Hunziker 24745 (CORD) JUJ, SAL Dried aerial parts. Solamine: alkaloid Solanum tweedianum Hook. Tuber: anti-ulcer, hepatic, No biological test No data Papilla ophtalmic Solanum atriplicifolium Gillies BAI, COS, ERI, LPA ex Nees Barboza 1998 (CORD) Solanum valdiviense Dunal Leaf: febrifuge, No biological test Dried entire plant. Scopolin : Huevil gynecological/obstetric coumarin Chiapella 1758 (CORD) NEU Vassobia breviflora Leaf: nocive, madurating, for Stem + leaf: antimicrobial Stem + leaf: Jaborosalactones A, B, D (Sendtn.) Hunz. earaches, odontalgic activity (sub nom. Acnistus breviflorus) Calchal de gallina, candelilla, Stem + sprout: cicatrizant ischiví, sacha perilla, palo ne- BAI, CAT, CHA, COR, COS, gro, piscoyuyo, chulque, DFE, ERI, FOR, JUJ, LRI, MIS, ischivil SAL, SDE, SFE, SLU, TUC Acnistus breviflorus Sendtn.

Hunziker 10013 (CORD) KURTZIANA STERCULIACEAE Byttneria filipes Mart. ex K. Leaf: muscular cramps, pain in all No biological test No data Schum. muscles Sarandí BAI, CHA, COS, ERI, FOR, SAL, Krapovickas 11349 (CTES) SFE

BARBOZA, G.E.etal.MedicinalfloraofArgentina Guazuma ulmifolia Lam. Bark: sudorific, emollient, Bark: antibacterial and Dried stem bark. Catechin,epi: var. ulmifolia astringent, depurative, anti- hypotensive activity flavonoid Marmelero, camba-acá, ingá- syphilitic, for gonorrhea and Leaf essential oil. β-caryophyllene: hú, ingá negro, guazuma stomach-aches; decoction: for sesquiterpene; precocene: oxygen Cristóbal 2153 (CTES) leprosy and malaria, antidysenteric heterocycle Dried bark + fruit, decoction: to treat hemorrhage Dried leaf, infusion: antidysenteric and kidney disease CHA, COS, FOR Melochia pyramidata L. Young leaf: for fever Aerial parts: produce paralysis, Aerial parts. Melochinine: pyridone var. pyramidata CHA, COS, ERI, FOR, MIS, SAL, bradypnea, bradycardia and alkaloid Cocucci et al. 2915 (CORD) SDE, SFE hypotension Waltheria communis A. St.- Dried leaf + stem, decoction: Stem: weak antimicrobial Stem. Waltherione A, waltherione B, Hil. against pulmonary diseases activity (sub nom. W. vanessine, antidesmone, O- Waltheria douradinha A. St.- Part not specified: vulnerary, douradinha) methyltembamide: quinolone alkaloids Hil. anticatarrhal Root bark: antibacterial activity (sub nom. W. douradinha) Deginani 1647 (SI) COS, ERI, FOR, JUJ, MIS, SAL (sub nom. W. douradinha) Dried root bark. Adouetine; waltherine A: quinolinone alkaloid; chamaedrine, adouetine X, frangulaline, scutianine B, scutianine C: cyclic peptide alkaloids; waltherione A, parasorbic acid, propacine, and (−)- epicatequine (sub nom. W. douradinha) STYRACACEAE Styrax leprosus Hook. & Arn. Dried resin, decoction: to treat No biological test Wood. Tannin Carne de vaca, maría molle, urinary tract infections, against Ibirá-cuatí, Ivirá-cuatí diarrhea, for cutaneous treatments Ariza Espinar 1161 (CORD) COR, MIS THYMELACEAE Ovidia andina (Poepp. & Part not specified: laxative, No biological test Leaf + stem. Apigenin-4'-7-dimethyl Endl.) Meisn. appetite stimulant, hepatic- ether: flavone; daphnetin: coumarin Pillo-pillo, piyo-piyo, lloime, intestinal palo hediondo CHU, NEU, RNE 315 Forcone 450 (CORD)

TILIACEAE 316

Heliocarpus popayanensis Leaf bud: lymphatics glands, No biological test No data Tomo34(1-2):7-365.2009 Kunth swelling, ant’s bite, sting ray, Afata blanca, ibirá-piré-hú, childbirth aperivá, amor seco CAT, JUJ, MIS, SAL, SDE, TUC Dematteis 123 (CTES) Luehea divaricata Mart. Bark: hepatic, digestive, Dried leaf + stem: mutagenic, Dried leaf. 3β-p-hydroxybenzoyl- Sota caballo, azota caballo, antidiarrheal, tonic, febrifuge, antibacterial, antifungal, and tormentic acid, the maslinic acid, ibatinguí, ibatanguí, árbol de astringent antiproliferative activity vitexin, glucopyranosylsitosterol, C- San Francisco Dried leaf + stem, infusión: glycoside flavone Cocucci 3236 (CORD) anti-inflammatory, diuretic Stem bark: (-)-epicatechin: flavonoid Dried leaf:anti-inflammatroy, antidysenteric; against diarrhea, rheumatism, antispasmodic, and urinary and respiratory diseases Flowers: sedative, for bronchitis, cicatrizant Root: depurative, anti-inflammatory BAI, CHA, COS, ERI, FOR, MIS, SFE Triumfetta semitriloba Leaf: for venereal diseases, Fresh wood: antiulcer activity Dried root. β-sitosterol: sterol Jacq. astringent; infusion: for hernia Tolaba 2628 (CORD) Root, decoction: to treat diarrhea Fresh root, infusion: for urinary problems, to prevent miscarriage and constipation BAI, CHA, COS, FOR, JUJ, MIS, SAL TROPAEOLACEAE Tropaeolum pentaphyllum Leaf + flowers: antiscorbutic No biological test No data KURTZIANA Lam. subsp. pentaphyllum BAI, CHA, COR, COS, ERI, FOR, Flor de pitito MIS, SFE Pedersen 13418 (CTES, SI) TURNERACEAE Turnera krapovickasii Arbo Leaf: tonic, astringent, diuretic, No biological test No data Cocucci 2013 (CORD) expectorant JUJ, SAL, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Turnera sidoides subsp. Aerial parts: for lumbago and No biological test No data pinnatifida (Juss. ex Poir.) prolapse Arbo BAI, CAT, CHA, COR, COS, ERI, Damiana, yerba del ciervo FOR, JUJ, LPA, LRI, RNE, SAL, Subils 644 (CORD) SDE, SFE, SLU, TUC URTICACEAE Boehmeria caudata Sw. Root: against urinary affections, to Stem: cytotoxic activity Stem. Cryptopleurine: quinolizidine Rupa grande, ramio induce abortion alkaloid tucumano, retama tucumana, BAI, COS, JUJ, MIS, SAL, TUC Root. Oleanolic acid 3-O -˜-D- ortiga, sacha tabaco arabinoside: triterpene Guaglianone 2941 (SI) Parietaria debilis G. Forst. Dried entire plant, decoction: to No biological test No data Anisillo, comida de oveja, treat urinary tract infections parietaria, yerba fresca, Aerial parts: emollient, abluent, ratonera, paletaria vulnerary, hepatic, cicatrizant, for Cantero et al. s.n. (RIOC urinary tract problems, intestinal 1243) disorders, and skin eruptions Leaf: diuretic, lithotriptic, stomachic, hypoglycaemic BAI, CAT, CHA, CHU, COR, COS, DFE, ERI, FOR, JUJ, LPA, LRI, MEN, MIS, RNE, SAL, SDE, SFE, SJU, SLU, TUC Urera aurantiaca Wedd. Leaf: antirrheumatic No biological test No data Ortiga colorada, pino CHA, COS, ERI, FOR, JUJ, MIS, Guillén 172 (SI) SAL, SFE Urera baccifera (L.) Gaudich. Entire plant: emmenagogue, Dried entire plant: No data Ortigón, ortiga del monte, counterirritant, to treat snakebite antibacterial, antifungal, ortiga brava, ortiguilla and skin infections; for rheumatic antiyeast, antimycobacterial pino guazú, itapalla grande, pains, persistent fever, wounds, activity orteguilla ulcers, bruises, sores, leucorrhea, Fresh entire plant: Urera caracasana Molfino brain cancer, and vaginitis molluscicidal activity Novara 11074 (CORD) 317

318 Urera baccifera (L.) Gaudich. Leaf (immature), infusion: for Root: antibacterial activity (continuation) dermato-mucosal lesions, Dried bark + leaf: molluscicidal Tomo34(1-2):7-365.2009 emmenagogue, for skin diseases activity and irritations; infusion: anti- Leaf: antibacterial, antifungal, inflammatory, for skin fungal analgesic, anti-edematogenic diseases and erysipelas (edema induced by snakebit), Leaf, juice: for rheumatism, aches and anti-inflammatory activity; and body pains (including toxicity assessment headaches), febrifuge; decoction: Fresh trichomes: toxic effect to treat arthritis (general) Root, infusion: for gonorrhea and amenorrhea and infections Part not specified: antivenin, odontalgic CAT, CHA, COS, FOR, JUJ, MIS, SAL, TUC Urtica circularis (Hicken) Aerial parts: hypotensive, to No biological test No data Sorarú reduce weight, antirheumatic, for Ortiga, ortiga blanca cardiovascular and circulatory Martínez 378 (CORD) diseases Root: hepatic, antitussive BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SAL, SDE, SFE, SJU, SLU, TUC Urtica magellanica Poir. Dried aerial parts, infusion: No biological test No data Ortiga hemostatic Boelcke 5541 (SI) Leaf: skin diseases; infusión: for rheumatism CHU, NEU, RNE, SCR, TDF Urtica mollis Steud. Leaf: astringent, cholalogue, No biological test No data Urtica dioica var. mollis diuretic (Steud.) Wedd. BAI, CAT, CHA, CHU, COR, KURTZIANA Cantero et al. s.n. (RIOC 696) JUJ, LRI, MEN, NEU, RNE, SAL, SJU, TUC Urtica spathulata Sm. Leaf: astringent, diuretic, No biological test No data Ortiga brava, ortiga crespa, cholalogue ortiga crespona BAI, CAT, COR, COS, DFE, ERI, Hunziker 7835 (CORD) LPA, SCR, SDE, SFE, SLU, TUC

VALERIANACEAE BARBOZA, G.E.etal.MedicinalfloraofArgentina Valeriana carnosa Sm. Root: sedative, antispamodic, No biological test Dried entire plant. Phenyl-propenoic Ñanculahuén, yerba del diuretic, digestive, hepatic, acid,trans: 3-4-dihydroxy: aguilucho, ñancolawen antitussive, for rheumatism; for phenylpropanoid; (+)-1-hydroxy-2,6- Burkart 14311 (SI) liver, lungs, heart, stomach, di(4-hydroxy-3-methoxyphenyl)-3,7- bladder and blood symptoms dioxabicyclo[ 3.3.0] octave, (+)-1,5- CHU, M EN, NEU , RNE , SCR, dihydroxy-2(S),6(S)-di(4-hydroxy-3- TDF methoxyphenyl)-3,7-dioxabicyclo[ 3.3.0] octane: lignans Valeriana clarionifolia Phil. Root + rhizomes: antirheumatic, No biological test No data Ñancolawen digestive, respiratory disoders, Donat 190a (SI) kidney disorders, cardioactive CHU, MEN, NEU, RNE, SCR Valeriana effusa Griseb. Root stalk + root: sedative No biological test No data Valeriana, yerba gatera, CAT, COR, JUJ, LRI, SAL, TUC ñancu louen Stuckert 10109 (CORD) Valeriana ferax (Griseb.) Root stalk + root: sedative No biological test No data Höck COR Dorlado Hunziker 9047 (CORD) Valeriana lapathifolia Vahl Root: antispamodic No biological test Leaf. Acevaltrate, valtrate: iridoid Gerling 23 (SI) CHU, NEU, RNE, SCR monoterpene Valeriana polybotrya Root stalk + root: sedative No biological test No data (Griseb.) Höck CAT, JUJ, SAL, TUC Bianco & Cantero s.n. (RIOC 788) VERBENACEAE Acantholippia deserticola Aerial parts: stomachic, digestive, Aerial parts essential oil: Aerial parts. α-thujone, β-thujone; (Phil.) Moldenke febrifuge, antidiarrheic, antiseptic, antimicrobial activity sabinene: monoterpene hydrocarbons; Rica-rica, chaupi diaphoretic Leaf + aerial parts: antioxidant terpinen-4-ol: monoterpene alcohols; Acantholippia punensis Botta (sub nom. A. punensis) activity carvacrol: phenol; α-curcumene: Novara 5703 (SI) CAT, JUJ, SAL, SJU sesquiterpene hydrocarbon; p- isopropyl-benzaldehyde: cumin 319 aldehyde; lupeol, β-amyrine: triterpenoids

Acantholippia salsoloides Aerial parts: digestive, No biological test No data 320 Griseb. antidiarrheic, antiseptic, stomachic, Rica-rica, chaupi diaphoretic Tomo34(1-2):7-365.2009 Cabrera 7716 (SI) CAT, JUJ, LRI, SAL Acantholippia seriphioides Stem, leaf + flowers: stomachic, Plant essential oil: acaricidal Aerial parts essential oil. Thymol, p- (A. Gray) Moldenke gastrointestinal, diaphoretic, effect; antioxidant and cymene, carvacrol, γ-terpinene; Tomillo, tomillo del campo, against the influenza antimicrobial activity carvacrol, citral, p-cymene, geranial, tomillo mendocino, tomillo Leaf and stem: aphrodisiac piperitone, thymol (sub nom. L. macho, tomillo de olor, BAI, CHU, LPA, MEN, NEU, seriphioides) tomillo hembra, ñancuñán, RNE, SCR, SJU, SLU tomatillo silvestre Lippia seriphioides A. Gray Di Fulvio 10 (CORD) Aloysia citriodora Palau Plant: digestive, eupeptic, Aerial parts: giardicidal, Leaf essential oil. Neral, geranial, nerol, Chaquesayasaya, cedrón, antispasmodic, carminative, tonic analgesic, antiinflammatory, geraniol, sesquiterpenoids ar-curcumene, verbena citronela, limón Leaf: stomachache, cardiotonic, antipyretic, sedative, pro- bicyclosesquiphellandrene, spathulenol, verbena, haurippampacay, febrifuge, sedative, diuretic, and convulsant activity nerolidol, ß-bourbonene, trans-ß- verbena olorosa, yerba de la antispasmodic, odontalgic, against Leaf essential oil: antidiarrheal, caryophyllene, caryophyllene-2,6β-oxide, princesa, yerba Luisa hemorrhoids nematicidal, protective, limonene, geranyl acetate; β-citronellene, Aloysia triphylla (L’Hér.) Leaf + flower: anti-emetic, for antimicrobial, and antigenotoxic β-pinene, neryl acetate, trans-calamenene, Britton heart problems, and back ache activity, spasmolytic effect α-thujone, cis-carveol, carvone, 1,8- Cabrera 24637 (SI) CAT, JUJ, LRI, SAL (sub nom. A. triphylla) cineole, caryophyllene oxide; linalool Leaf. Vervain; geniposidic acid, geniposide, mussaenoside: iridoid glucosides; luteolin 7-diglucuronide: flavonoid (sub nom. A. triphylla); salvigenin, eupatorin, eupafolin, verbascoside (or acteoside), hispidulin, 6- hydroxyluteolin, luteolin 7-O-β- glucoside, luteolin, cismaritin, diosmetin, cirsiliol, chrysoeriol apygenin, pectolin-arigenin (sub nom. L. citriodora) Flower + leaf: geranial, neral, limonene KURTZIANA (sub nom. A. triphylla) Flower oil: 1-Octene, 1-octen-3-ol, p- cymene, (Z)-β-ocimene, trans-carveol (sub nom. A. triphylla) Leaf oil: p-cymene and trans-carveol; β- citronellene, β-pinene, neryl acetate, trans- calamenene (sub nom. A. triphylla)

Aloysia gratissima var. Aerial parts: stomachache, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina chacoënsis (Moldenke) Botta digestive, anticatarrhal, sedative Azahar del campo, niño rupá Leaf: diaphoretic, digestive chico, palo de ángel, poleo Leaf + flowers: cardiotonic, chaqueño, poleo del campo carminative Krapovickas 17299 (SI) CAT, CHA, COR, FOR SAL, SDE, SFE Aloysia gratissima (Gillies Aerial parts: to treat varicose Aerial parts essential oil: Aerial parts essential oil. & Hook. ex Hook.) Tronc. veins and dizziness antimicrobial, virucidal and Bicyclogermacrene, ˜-bisabole ne, var. gratissima Stem: to treat hypotension nematicidal activity camphene, cadinol, caryophyllene oxide, Arrayán, arrayán del campo, Leaf: to sooth menstrual pains and Dried leaf: antimalarial activity limonene oxide, chiysanthenyl acetate, α- azahar del campo, cedrón, against hemorrhoids and β-caryophyllene, β-elemene, azar del monte, favorita, palo, Flowers + leaf: cardiotonic, viridiflorol, linalool, α- and β-thujone, 10- muña del monte, palo stomachic, to relieve the epi-cubebol, (E)-nerolidol, germacrene D, amarillo, usillo, niño rupá stomachache, carminative, eucalyptol, citral, pulegone, sabinene, α- Morrone 635 (SI) diaphoretic and ˜ -pinene, limonene, terpinyl acetate, BAI, CAT, COR, COS, ERI, FOR, eugenol; myrcene, γ-terpinen-1-al, trans- LPA, MEN, MIS, SDE, SFE, SJU, pinocarveol, cis-pinocarveol, γ- and δ- SLU, TUC elemene, geranyl acetate, β-cubebene, spathulenol, globulol, α-humulene, alloaromadendrene, γ-gurjunene, cubebol, elemol, germacrene B, carotol Aerial parts. Guaiol, bisabolol, spathulenol: sesquiterpenoids; a-amirin, betulinic acid, oleanolic acid, ursolic acid: triterpenoids; apigenin 5-hydroxy- 7,40-dimethylether, genkwanin, luteolin 7,30,40-trimethylether: flavonoids; hoffmanniaketone: ent-kaurane; rutin: glycoside flavonol; verbascoside, arenarioside: phenylethanoids Aloysia polystachya Aerial part: to expel the placenta Essential oil: nematicidal Aerial parts essential oil. α-and β- (Griseb.) Moldenke and as protective post partum activity; fumigant and repellent thujone, α-thujene, carvone, limonene, Burro, té de burro, poleo de Leaf, decoction: to alleviate activity against head lice sabinene, α and β-pinene, carvacrol, Castilla, poleo real, burrito, itching and irritations and to treat Aerial parts: antidepressant eucarvone, camphene, p-cymene, yerba del burro, poleo riojano skin mycosis and anxiolytic-like effects, myrcene, α-terpineol, pulegone, β- Hunziker 8951 (CORD) Leaf and flowers: tonic-digestive, antibacterial activity caryophyllene, α-humulene, δ and γ- to relieve the stomach-ache, Leaf extract: sedative– cadinene, τ-cadinol, spathunelol, hepatic, against the influeza anxiolytic and antidepressant lippifoli-1(6)-en-5-one 321 CAT, COR, COS, LRI, SAL, SDE, activity SJU, SLU

Aloysia virgata (Ruiz & Aerial parts: menorrhagia, for Dried aerial parts: Dried leaf. Hoffmanniaketone and its 322

Pav.) Juss. var. virgata skin affections molluscicidal activity monoacetate: kauranes; verbascoside, Tomo34(1-2):7-365.2009 Cedrón del monte, niño rupá, Leaf: antimicotic, diaphoretic, Stem bark: antiplasmodial arenarioside: phenylethanoids; luteolin: niño urupá mayor anticatarrhal, for stomachaches activity flavonoid Múlgura 925 (SI) MIS Aerial parts essential oil. Germacrene D, β-caryophyllene, α-humulene, bicyclogermacrene Glandularia aristigera (S. Entire plant: for leukorrhea No biological test No data Moore) Tronc. and snakebites, anti-inflammatory; Barboza 1155 (CORD) decoction: hemostatic, antidiarrheal BAI, CHA, COS, ERI, FOR, MIS Glandularia crithmifolia Part not specified: medicinal No biological test No data (Gillies & Hook.) Schnack & CHU, LPA, LRI, MEN, NEU, Covas RNE, SJU, SLU Forcone 71 (CORD) Glandularia dissecta (Willd. Aerial parts: nervine No biological test No data ex Spreng.) Schnack & Covas BAI, CAT, CHA, COR, ERI, FOR, Verbena MIS, SAL, SDE, TUC Krapovickas 3086 (CTES) Glandularia hookeriana Leaf: abluent No biological test No data Covas & Schnack BAI, CAT, COR, LPA, LRI, Yerba de la chiva, margarita MEN, NEU, RNE, SAL, SDE, amarga, bichicho, té de SJU, SLU burro Hunziker 14824 (CORD) Glandularia incisa (Hook.) Entire plant: antidiarrheal, for No biological test No data Tronc. leukorrhea and snakebites, anti- Margarita inflammatory

Cocucci 3146 (CORD) BAI, CHA, COS, ERI, FOR, MIS, KURTZIANA SFE Glandularia laciniata (L.) Part not specified: anti-emetic, No biological test No data Schnack & Covas stimulant Verbena laciniata (L.) Briq. BAI, CAT, CHA, COR, COS, Hunziker 16107 (CORD) LPA, LRI, MEN, RNE, SAL, SDE, SFE, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Glandularia origenes (Phil.) Part not specified: stomachic No biological test No data Schnack & Covas COR, LRI, MEN, SAL, SJU Luti 5584 (SI) Glandularia peruviana (L.) Aerial parts: cicatrizant No biological test No data Small Leaf: antispasmodic, stomachic, Margarita punzó, margarita abluent ophtalmic roja, verbena roja, verbena BAI, CAT, CHA, COR, COS, ERI, Bonzani 100 (CORD) FOR, JUJ, MIS, SAL, SFE, SLU, TUC Glandularia platensis Leaf + flowers: febrifuge, icteric, No biological test No data (Spreng.) Schnack & Covas ophtalmic Verbena blanca, margarita BAI, CAT, CHA, COR, COS, ERI, blanca JUJ, LPA, LRI, RNE, SAL, SJU, Hunziker 7557 (CORD) TUC Glandularia pulchella Leaf + flowers: icteric, ophtalmic No biological test No data (Sweet) Tronc. var. pulchella BAI, COR, COS, ERI, MIS, SFE Verbena de las sierras Múlgura de Romero 3489 (SI) Glandularia tenera Part not specified: stomachic, No biological test No data (Spreng.) Cabrera diuretic, emmenagogue Hunziker 12742 (CORD) BAI, CAT, CHA, COR, COS, ERI, JUJ, LPA, LRI, MEN, RNE, SFE, SJU, SLU Junellia asparagoides Part not specified: diaphoretic, No biological test No data (Gillies & Hook.) Moldenke stomachic Barba de viejo, tomillo, CAT, JUJ, LRI, MEN, SAL, SJU, verbena TUC Barboza 1154 (CORD) Junellia juniperina (Lag.) Part not specified: depurative No biological test No data Moldenke CAT, LRI, MEN, SAL, SJU, TUC Monte de la yegua

323 Forcone 303 (CORD)

324 Junellia seriphioides (Gillies Cutting: diuretic, digestive, for No biological test Dried entire plant. 9-hydroxy-8- & Hook. ex Hook.) Moldenke gastrointestinal disorders epihastatoside, auroside, pulchelloside Tomo34(1-2):7-365.2009 Alagarto, espina de llama, espi- CAT, CHU, JUJ, LPA, LRI, MEN, I, 8-epihastatoside, verbascoside: na de pescado, lagaña de la vir- NEU, RNE, SAL, SJU, SLU iridoid glucosides; oleanolic acid: gen, leña de lagarto, ñancuñán, triterpene perlita, rosita, tomillo, tomillo del campo, tomillo macho Negritto 447 (CORD) Lampaya castellani Moldenke Leaf + stem: diaphoretic, to treat No biological test No data Lampais, lampa, lampazo, rheumatism, for pain in lampayo, lampaia menstruation Kiesling 3986 (SI) JUJ Lantana balansae Briquet Stem + leaf: febrifuge Branches: bactericidal activity No data Lantana de la sierra Root: abortifacient, emmenagogue, Ariza Espinar 2211 (CORD) laxative BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LRI, MIS, SFE, TUC Lantana camara L. Dried aerial parts, decoction: to Aerial parts essential oil: Dried entire plant. Camarinic acid: Camará, camará de dos colo- treat mange; infusion: antibacterial, antifungal, and triterpene; flavone,5-hydroxy-4'-6- res, bandera española, lanta- abortifacient, to treat malaria and hepatotoxic activity dimethoxy: 7-O-β-d-glucoside: flavone na, caburá caá, cambará, hier- rheumatism, for digestive disorders Leaf essential oil: Dried aerial parts. Betulinic acid: ba de Cristo, yerba de la cruz Dried bark, infusion: sedative, antileishmanial activity triterpene; ajugose: carbohydrate; Hunziker 25600 (CORD) tonic, for rheumatism theveside, theviridoside, geniposide, Leaf, decoction: vomitive; shanzhiside-Me-ester, lamiridoside, 8- infusion: sedative, for rheumatism, epiloganin: iridoid glucosides diaphoretic Dried stem. α-amyrin: triterpene Dried root. Theveside: iridoid monoterpene; 7-methoxy, and 6- methoxynaphtho[2,3-b]-furan-4-9-

quinones; 5-hydroxy-7- KURTZIANA methoxynaphtho[2,3-b]-furan-4-9- quinone; 8-hydroxy-6- methoxynaphtho[2,3-b]-furan-4-9- quinone; 6- and 7-

BARBOZA, G.E.etal.MedicinalfloraofArgentina Lantana camara L. Flowers + leaf: febrifuge, methoxydiodantunezone; 6- and 7- (continuation) cephalalgic, for treating wounds isomethoxydiodantunezone; 6- and 7- externally, antimicrobial, methoxy-naphtho[2,3-b]-furan-4-9- emmenagogue, digestive, anti- quinones; 5, 7- dimethoxy-naphtho[2,3- odontalgic, antitussive, b]-furan-4-9-quinones; 6, 8- dimethoxy- antirheumatic naphtho[2,3-b]-furan-4-9-quinones; 5- Fruit + leaf: hepatoxic hydroxy-6-methoxy-naphtho[2,3-b]- Fresh fruit, infusion: for coughs furan-4-9-quinone; 8-hydroxy-7- BAI, COR, COS, DFE, ERI, FOR, methoxy-naphtho[2,3-b]-furan-4-9- MIS, SAL, SFE, TUC quinone Aerial parts essential oil (pink-violet flower type): davanone, β- caryophyllene, sabinene, linalool, α- humulene Aerial parts essential oil (yellow- orange type): β-caryophyllene, β- bisabolene, sabinene, γ-cadinene, α- humulene Lantana grisebachii Seckt Leaf + stem: febrifuge Aerial parts: antimicrobial and No data var. grisebachii CHA, COR, ERI, FOR, LRI, SFE, antioxidant activity Palo de angel, lantana SLU, TUC Hunziker 9745 (CORD) Lantana megapotamica Aerial parts: febrifuge, No biological test Aerial parts. Ipolamiide: iridoid (Spreng.) Tronc. antirheumatic, diuretic, stomachic glucoside Lantana de las sierras BAI, COR, COS, ERI, FOR, MIS, Cantero et al. s.n. (RIOC 2100) SLU Lantana montevidensis Leaf : analgesic, febrifugal, Dried leaf: antiproliferation Leaf. Luteolin apigenin; cirsilineol, (Spreng.) Briq. anticatarrhal, antirrheumatic, activity eupatorin, 5,4'-dihydroxy-6,7,3',5'- Martínez 427 (CORD) antispasmodic, carminative, tetramethoxyflavone, 5,6-dihydroxy- digestive, sudorific 7,3',4'-trimethoxyflavone, 5,6,4'- BAI, CAT, COS, ERI, FOR, MIS, trihydroxy-7,3',5'-trimethoxyflavone, SFE 5,6,3'-trihydroxy-7,4'- dimethoxyflavone, 5,3',4'-trihydroxy- 6,7,5'-trimethoxyflavone, cirsiliol,

hispidulin, eupafolin: 5,6,7-oxygenated 325 flavones; theviridoside: iridoid glucoside

Lippia alba (Mill.) N. E. Br. Aerial parts: bradicardic Entire plant: hypotensive Dried leaf. Calceolarioside A: 326 var. alba Dried branches: for parasites and and phenylpropanoid; 1-8-cineol: monoterpene; Romerillo, salvia morada, diarrhea anticrustacean activity theveside, theviridoside: iridioid glucosides; Tomo34(1-2):7-365.2009 salvia de campo o de monte, Leaf: digestive, febrifuge; infusion: Aerial parts: giardicidal flavonoid 4-sulphates, tannins, geniposide salvia trepadora, salvia for diarrhea and stomachache, activity (iridoid), triterpenic saponins, resin, mucilages maestra, salvia de jardín, analgesic, anti-inflammatory, and/or Dried leaf: CNS Plant essential oil. (-) piperitone, toronjil, salvia de Castilla, antipyretic, to treat cutaneous depressant, analgesic, (+)limonene, 1,8-cineole, caryophyllene, salvia de las sierras, salvia diseases, burns, wounds, ulcers anti-inflammatory, sabinene, linalool, bornyl acetate, α-pinene, salvaje Part not specified: stomachic, for antipyretic, antiviral, β-pinene, β-yrcene, p-cymene, α-terpineol, Burkart 21365 (SI) abortion, nausea, and asthma, cytostatic, anticonvulsant, linalyl acetate, cytronellyl acetate, carvone, antispasmodic, emmenagogue and antimycobacterial borneol, α-muurolene, citronellol, geranial, BAI, CHA, COR, COS, ERI, FOR, activity neral, β-elemene, γ-cadinene, 2-undecanone JUJ, MIS, SAL,SFE Leaf essential oil: allo-aromadendrene, caryophyllene oxide, antibacterial activity dihydrocarvone, camphor, α- and β-cubebene, myrcenone, copaene Lippia grisebachiana Leaf: stomachic, purgative, No biological test Aerial parts essential oil. α-terpineol, Moldenke sudorific, antispamodic dihydrocarvone, β-caryophyllene, linalool, Salvia morada, poleo CAT, COR, COS, JUJ, LRI, SAL, myrcene, piperitone, pulegone, linalyl acetate Cabrera 12943 (SI) SDE, SLU, TUC Lippia integrifolia (Griseb.) Leaf + flowers: digestive, to Aerial parts: Fresh essential oil. α-thujene, sabinene, p- Hieron. relieve the stomachache, trypanocidal, choleretic, cymene, limonene, terpinen-4-ol, borneol, Pulco, poleo, incayuyo, té del emmenagogue, antigripal, and antispasmodic activity eremophyllene, γ-elemene, β-caryophyllene, δ- inca, manzanilla antitussive, carminative elemene, α-humulene, african-1-en-6-ol, african- Ariza Espinar 3161 (CORD) Dried aerial parts, infusion: 4-5-dione,4-5-seco, africanone, spathulenol, S- nervine, stomachic, emmenagogue, (+)-trans-nerolidol, 2β,9α-2,6,6,9- tonic, diuretic tetramethyltricyclo[6.3.0.0(2,4)]undec-1(8)-ene- CAT, COR, JUJ, LRI, SAL, SJU, 67,11-dione, 1β,2α,8β-2,6,6,10- TUC tetramethylbicyclo[6.3.0]undec-5-en-2-ol (3α- hydroxy-6-asteriscane), 1α,7β,9a-1-hydroxy- 3,6,6,9-tetramethylbicyclo[5.4.0]undec-3-en-8-on, lippifoli-1(6)-en-5-one, lippifoliane, 1,6-cis- lippifolian-1α-ol-5-one, 1,6-trans-lippifolian-1α- ol-5-one, lippifoli-1(6)-en-4β-ol-5-one, trans- KURTZIANA africanan-1α-ol, african-5-en-1α-ol, β- caryophyllene oxide, 4,5-seco-africanan-4,5- dione, humulene epoxide II, ketone 4, 1,6-cis- and 1,6-trans-lippifolian-1α-ol-5-one, lippifoli- 1(6)-en-4α-ol-5-one; integrifolian-1,5-dione, asteriscane, ; bicyclohumulendione, humulendione, trans-humul-(9E)-en-2,6-dione,

BARBOZA, G.E.etal.MedicinalfloraofArgentina Lippia junelliana Leaf + stem: digestive Essential oil: virucidal and Leaf essential oil. α-bisabolene, (Moldenke) Tronc. CAT, COR, JUJ, LRI, SAL, SDE, nematicidal activity borneol, limonene, piperitenone, Salvia, salvia de la cabra, SJU, SLU, TUC camphor, ocimenone, myrcene, poleo, salvialora. piperitenone oxide, spathulenol, 1,8- Ariza Espinar 3133 (CORD) cineol, α-bisabolol, E-nerolidol, davanone, carvone, piperitone, cis- dihydrocarvone, myrcenone, bicyclogermacrene, β-caryophyllene, (E)-tagetenone Lippia laxibracteata Herzog Medicinal No biological test Aerial parts essential oil. Thymol, p- Hunziker 18382 (CORD) CAT, COS, LRI, SAL, SDE, TUC cymene, cis-β-ocimene, carvacrol Lippia turbinata f. Aerial parts: for back ache Essential oil: nematicidal Aerial parts essential oil. Carvone, magnifolia Moldenke Leaf + stem: digestive, diuretic, activity piperitone oxide, limonene, pulegone, Poleo tonic, emmenagogue, abortifacient piperitone Lippia fissicalyx Tronc. CHA, JUJ, SAL, TUC (sub nom. L. fissicalyx) Burkart 11097 (SI) Lippia turbinata Griseb. f. Aerial parts, infusion: stimulant, Dried entire plant: Dried aerial parts. Lantanilic acid, turbinata diuretic, digestive antimicrobial activity camaric acid: triterpenes; alkaloids, Poleo, té del país, poleo fino Leaf + stem: digestive, diuretic, Aerial parts essential oil: leucoanthocyanidins, steroidic triterpenic Bonzani 106 (CORD) emmenagogue, abortifacient virucidal activity compounds, cardenolides (traces) Leaf, infusion: abortifacient, Dried leaf. Theveside: iridoid bradicardic, emmenagogueBAI, monoterpene CAT, CHA, COR, JUJ, LPA, LRI, Essential oil. Carvone, lippiaphenol: MEN, SAL, SDE, SFE, SJU, SLU, monoterpene; 3 β, 25-epoxy-3 α, 21 α – TUC dihydroxy-olean-12-ene-28-oic acid; 3 β, 25-epoxy-3 α, 21 α –dihydroxy-22β- angeloyloxylean-12-ene-28-oic acid; 3 β, 25-epoxy-3 α, 21 α –dihydroxy-22β- tigloyloxylean-12-ene-28-oic acid; 3 β, 25- epoxy-3 α, 21 α –dihydroxy-22β-(2- methylbutan-l-oyloxy)olean-12-ene-28-oic acid: triterpenoids; limonene, α-terpineol, piperitenone, pepiretenone oxide, methyleugenol, (E)-caryophyllene, α- humulene, spathulenol, lantanolic acid, rehmannic acid Flowers + whole plant: thujone 327

328 Phyla canescens (Kunth) Leaf: stomachic Aerial parts: antimicrobial Aerial parts. Flavone aglycones, Tomo34(1-2):7-365.2009 Greene BAI, CHU, COR, COS, ERI, FOR, activity flavone mono- and di-sulphates Lippia canescens Kunth JUJ, MEN, NEU, RNE, SAL, (sub nom. L. canescens) Yerba del mosquito, Santa SDE, SFE María, yerba de la Virgen Cabrera 34617 (SI) Pitraea cuneato-ovata Leaf + stem: diuretic No biological test No data (Cav.) Caro CAT, CHA, COR, ERI, JUJ, LPA, Vara de San José, papilla, LRI, MEN, SAL, SDE, SFE, SJU, miel de vaca, papa de la zorra SLU, TUC Hunziker 21830 (CORD) Stachytarpheta cayennensis Dried aerial parts: stimulant, Dried entire plant: analgesic, Aerial parts. Ipolamiide: iridoid (Rich.) Vahl digestive; decoction: analgesic; antiulcer, laxative, antioxidant, monoterpene; phenylethanoid glycoside Té criollo infusion: to treat malaria, gastric antibacterial, antimalarial, and acetoside Cabrera 24500 (SI) and intestinal disorders anti-inflammatory activity Root. Verbascoside, isoverbascoside, Leaf, decoction: febrifuge, martinoside: glycosylateds purgative; sudorific, stimulant, phenylpropanoids antirheumatic, febrifuge, tonic, pectoral, antispamodic, diuretic, ear disorder Root + leaf: diuretic, analgesic, to treat sore skin, wounds, bronchial problems and rheumatism COS, ERI, JUJ, MIS, SAL, SFE Verbena bonariensis L. var. Aerial parts: cicatrizant, for Entire plant: hypoglycemic Dried entire plant. Nodiflowersetin bonariensis vaginal infections activity, anti-implantation effect Leaf. Verbenalin, verbenaloside, Verbena, yerba de fierro Leaf: antispamodic, emmenagogue griselinoside: iridoid glucosides Subils 706 (CORD) Flowers: pectoral KURTZIANA BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, MEN, MIS, RNE, SAL, SFE, SJU, SLU, TUC

Verbena gracilescens Entire plant: stomachic, No biological test No data BARBOZA, G.E.etal.MedicinalfloraofArgentina (Cham.) Herter var. cholalogue, antineuralgic, digestive, gracilescens febrifuge Hunziker 8115 (CORD) Aerial parts: digestive, antimicrobial Dried root: to promote fertility BAI, CAT, CHA, COR, COS, ERI, FOR, JUJ, LPA, LRI, MEN, RNE, SAL, SDE, SFE, SJU, SLU, TUC Verbena hispida Ruiz & Entire plant, decoction: for No biological test Dried entire plant. Cornin, Pav. var. hispida headaches verbenaloside, griselinoside: iridoid Barboza 64 (CORD) Leaf: hepatic, digestive, glucosides emmenagogue Part not specified, infusion: biliary regulant, for bilious and biliary colic CAT, CHA, COR, FOR, JUJ, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU, TUC Verbena intermedia Gillies Leaf: hepatic, digestive, No biological test No data & Hook. ex Hook. emmenagogue Verbena, siempreviva del Part not specified: abortifacient campo BAI, CHA, COR, COS, ERI, FOR, Subils 3297 (CORD) LPA, LRI, MEN, MIS, SAL, SDE, SFE, SJU, SLU Verbena litoralis Kunth var. Entire plant, decoction: for skin Dried aerial parts: Entire plant. Verbenalin, litoralis allergy antimalarial and verbenaloside, brasoside: iridoid Verbena encañutada, verbena Aerial parts: cicatrizant, anti- antimycobacterial activity glucosides del litoral, yerba del acero, inflammatory, neonatal and Dried aerial parts. Aurantiamide verbena paediatrics care, for menorrhage and acetate: proteid; brasoside: iridoid Cantero et al. s.n. (RIOC 416) menopause monoterpene; jionoside: Dried branch + leaf, decoction: phenylpropanoid; verbenachalcone: against diarrhea dimeric dihydrochalcone Leaf: hepatic, digestive, emmenagogue, cephalalgic, febrifuge Root: antitussive BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, LPA, LRI, MEN, MIS, 329 NEU, RNE, SAL, SDE, SFE, SJU, SLU, TUC

330 VIOLACEAE Hybanthus calceolaria (L.) Part not specified: emetic, No biological test No data Tomo34(1-2):7-365.2009 Oken purgative, expectorant, for Purga do campo dysentery Hunziker 15574 (CORD) COS, ERI, MIS Hybanthus hieronymi Aerial parts: contraceptive No biological test No data (Griseb.) Hassl. CAT, CHA, FOR, JUJ, SAL, SDE, Stuckert 16979 (CORD) TUC Hybanthus parviflorus Entire plant: emetic, purgative, No biological test Plant. Hypa A: macrocyclic (Mutis ex L. f.) Baill. antirheumatic polypeptide Violetilla, maitencillo BAI, CAT, CHA, COR, COS, ERI, Leaf. Quercetin: flavonol Ariza Espinar 293 (CORD) FOR, JUJ, LPA, LRI, MEN, MIS, RNE, SAL, SDE, SFE, SLU, TUC Hybanthus serratus (Phil.) Leaf + stem: emetic, purgative No biological test No data Hassl. Root: emetic Hunziker 7850 (CORD) BAI, CAT, COR, LPA, LRI, MEN, SAL, SDE, SJU, SLU, TUC Viola maculata Cav. var. Part not specified: pectoral, No biological test No data maculata diaphoretic, dermatologic Oreja de ratón CHU, NEU, RNE, SCR, TDF Cocucci 2441 (CORD) VISCACEAE Phoradendron argentinum Leaf: cardiotonic Dried leaf + stem: antimicrobial Leaf. Tyramine: isoquinoline alkaloid Urb. CAT, CHA, COR, FOR, JUJ, LRI, activity Corpo SAL, SDE, SFE, TUC (sub nom. P. pruinosum) Phoradendron pruinosum Urb. Hunziker 18853 (CORD) Phoradendron Leaf: antiashmatic; decoction: No biological test Leaf. Tyramine: isoquinoline alkaloid bathyoryctum Eichler anti-lithic KURTZIANA Liga Dried entire plant, infusion: Phorandendron hieronymi hypertensive Trel. CAT, CHA, COR, COS, FOR, Caro et al. 3327 (CORD) JUJ, LRI, MIS, SAL, SDE, SFE, SJU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Phoradendron liga (Gillies Leaf: cardiotonic, hypotensive Dried leaf + stem: cytotoxic Dried entire plant. Ligatoxin A, B: ex Hook. & Arn.) Eichler CAT, CHA, COR, COS, ERI, activity proteins Liga, muérdago, yerba del FOR, JUJ, LRI, MIS, SAL, SDE, Stem + leaf. Apigenin-6-C-xyloside, pajarito, palo tîreï, ca´avó SFE, SJU, SLU, TUC apigenin-6-C-glucoside, apigenin-6-C- tireï, madroño, madrugo galactoside, apigenin-8-C-glucoside, Hunziker 16313 (CORD) luteolin-8-C-xyloside, luteolin-6-C- xylosil-8-C-glucoside, luteolin-6-C- glucosil-8-C-glucoside, luteolin-8-C- xylosil-7-O-xyloside: flavon-C- glycosides; leucoapigeninidin, leucoluteolinidin, apigeninflavane, luteolinflavane, proapigeninidin: 3- desoxyproanthocyanidins Leaf. Tyramine: isoquinoline alkaloid Phoradendron Medicinal No biological test No data tucumanensis Urb. CAT, JUJ, SAL, TUC Suelda con suelda Venturi 3870 (SI) VITACEAE Cissus striata Ruiz & Pav. Leaf: astringent, hemostatic Dried leaf: antiviral activity No data subsp. striata CHU Pilpilvoqui Cusato 4401 (BAF) Cissus sulcicaulis (Baker) Part not specified: to treat feet No biological test No data Planch. skin injures Deginani 1693 (SI) COS, MIS Cissus verticillata (L.) Stem + root: against influenza, Plant: anticonvulsive, Leaf. Bicyclogermacrene, stilbene Nicolson & C. E. Jarvis antitussive, antiashmatic fungitoxic, oxytoxic, and resveratrol Cipó-pucá, cortina japonesa, Aerial part: for diabetes’s antibacterial activity; Aerial parts. Kaempferol 3-0- uva-brava, anil trepador, treatment and influenza, anti- vasoconstrictor effect; rhamnoside, quercetin 3-0-rhamnoside, insulina vegetal, bejuco caro, inflammatory, anti-epileptic, anti- antitumoral activity coumarin glycoside; flavones, añil trepador hypertension, diuretic, antithermic, Leaf: abortive and teratogenic flavonones, flavononols, Cissus sicyoides L. antirheumatic, anti-lipemic, against action (sub nom. C. sicyoides) leucoanthocianidins, saponins (sub Jörgensen 2771 (BA) respiratory infections nom. C. sicyoides) BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, MIS, SAL, SDE, SFE, 331 TUC

VIVIANACEAE 32 Viviana marifolia Cav. Part not specified: digestive, aromatic No biological test No data Té de burro NEU, SJU Tomo34(1-2):7-365.2009 Boelcke 14411 (SI) WINTERACEAE Drimys winteri J.R.Forst. Bark: bitter tonic Bark: anti-allergenic, Bark. Tannins, vitamin C; polygodial, 1-β-(p- & G. Forst. var. winteri Leaf and bark: stimulant, vulnerary, anti-inflammatory, methoxy-cynnamyl) polygodial, , Canelo, boighe antirheumatic, tonic, diuretic, antinociceptive, anti- astilbin, mukaadial, drimanial, drimenol, Goodall 2319 (BAB, SI) vermifuge, odonthalgic, antispasmodic hyperanalgesic activity drimene, drimenone, drimenine, isodrimenine, Leaf: for skin disorders (warts, ulcers, valdiviolide, α-chamigrene, ascaridol, α- and β- acne) pinene, 1,8-cineol, caryophyllene, limonene, CHU, NEU, RNE, SCR, TDF terpineol, eugenol, p-cymol, dipentene, cirsimaritin, taxifolin, procianidin, astilbin, luteolin, kaempferol, quercetin, ellagic acid, safrol, sesamin Leaf. 3 β-acetoxydrimenin, safrol, drimenol, polygodial, crytomeridiol, cirsimaritin, quercetin, astilbin, quercitrin ZYGOPHYLLACEAE Bulnesia bonariensis Griseb. Aerial parts: for treating wounds No biological test No data Jaboncillo, guale, laca, externally, cicatrizant, anti- guacle, glauca, guacho inflammatory, Hunziker 7966 (CORD) Bark, powder: cicatrizant CAT, CHA, COR, FOR, JUJ, LRI, SAL, SDE, SLU, TUC Bulnesia retama (Gillies ex Aerial parts: diuretic, cardiac stimulant No biological test Branches. Wax, resins, saponnins Hook. & Arn.) Griseb. CAT, COR, LPA, LRI, MEN, SDE, Retamo, calato, retamillo SJU, SLU Cocucci et al. 359 (CORD) Bulnesia sarmientoi Lorentz Bark: sudorific, depurative, diuretic, Bark + medulla: Part not specified. α-bulnesene, β- ex Griseb. diaphoretic, cordial bactericidal activity bulnesene, bulnesol, α-guaiene, τ-guaiene, Palo santo Wood: hepatic guaioside, guaioxiole, guanoxide, α-

Martínez 441 (CORD) Leaf, decoction: digestive patchoulene, guaiol KURTZIANA CHA, FOR, SAL Larrea cuneifolia Cav. Aerial parts: anti-inflammatory, for Dried entire plant: Leaf. Asparagine: protein Jarilla, jarilla macho, jarilla treating wounds externally, diaphoretic, antimicrobial and Dried leaf. Flavone,4'-5-7-trihydroxy-3-3'- crespa, jarilla norte-sur oxytocic, emmenagogue, for footbath antifungal activity dimethoxy: flavonol Cocucci et al. 361 (CORD) and rheumatism Essential oil. α-agarofuran,: sesquiterpene BAI, CAT, CHU, COR, LPA, LRI, MEN, NEU, RNE, SAL, SDE, SJU, SLU, TUC

BARBOZA, G.E.etal.MedicinalfloraofArgentina Larrea divaricata Cav. Aerial parts: anti-inflammatory, Dried leaf: antioxidant, acute Plant. Larreagenin A: nortriterpenoid; Jarilla, jarilla hembra, for treating wounds externally, antiulcerous, antimicrobial, nor-dihydroguaiaretic acid chamanilla, jarilla del cerro, diaphoretic, febrifuge, virucidal, and anti-inflammatory Plant essentials oil. α-thujene, yarilla emmenagogue, oxytocic, activity; immunomodulatory myrcene, limonene, E-ocimenone, Hunziker 22951 (CORD) odontalgic, antitussive, effects thymyl acetate, γ-elemene, spathulenol, antirheumatic, hypotensive, β-oplopenone, α-cadinol rubefacient, for footbath, anti- hyperlipidemic; to treat and prevent varicose veins BAI, CAT, CHU, COR, LPA, LRI, MEN, NEU, RNE, SAL, SDE, SJU, SLU, TUC Larrea nitida Cav. Dried leaf + stem, infusion: Leaf + stem: antitumor activity Aerial parts. Chalcone,2'-4'-dihydroxy: Jarilla crespa, jarilla de la emmenagogue Twigs + leaf resin: antioxidant flavonoid; quercetin-3-3'-7-trimethyl sierra, jarilla fina Part not specified: anti- activity ether: flavonol; nor-dihydroguaiaretic Hunziker 4644 (CORD) inflammatory, choleretic, acid, norisoguaiacine: lignans, ferulic antiperiodic, emmenagogue, acid: phenylpropane. sudorific, stimulant, balsamic, Leaf. Asparagine: proteid vulnerary BAI, CAT, CHU, LPA, LRI, MEN, NEU, RNE, SAL, SJU Plectrocarpa tetracantha Part not specified: balsamic, No biological test No data Gillies ex Hook. & Arn. emmenagogue, diaphoretic, Manca potrillo vulnerary Ariza Espinar 2906 (CORD) CAT, COR, JUJ, LRI, MEN, SDE, SJU, SLU Porlieria microphylla Leaf: for insomnia, to treat “evil No biological test No data (Baill.) Descole, O’Donell & eye” in children Lourteig Leaf + stem: antirheumatic, anti- Cucharero, chucupí, venereous, abluent, vulnerary, guayacán, falso guayacán, antitussive, antidiarrheal, for palo cuchara, pan de Cata hepatic disorders Subils 2128 (CORD) BAI, CAT, CHA, COR, COS, ERI,

FOR, JUJ, LRI, SAL, SDE, SFE, 333 SJU, SLU, TUC

334 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

APPENDIX II A detailed bibliography about uses is cited in Barboza et al. (2006). The most relevant literature referable to the uses of the species, and their chemical data or pharmacological properties not cited in or posterior to Barboza et al. (2006) is included in this Appendix.

Abad Martínez M. J., A. Latourrette Bessa & P. Bermejo Alburquerque U. P. 2006. Re-examing hypotheses Benito. 2005. Biologically active substances from the concerning the use and knowledge of medicinal plants: genus Baccharis L. (Compositae). En Atta-ur-Rahman a study in the Caatinga vegetation of N.E. Brazil. J. (ed.). Studies in Natural Products Chemistry: Ethnobot. Ethnomed. 2: 1-10. Bioactive Nat. Prod. (Part K) 30: 703-760. Alcalde S. M., S. B. Gorzalczany, M. L. Flores, O. L. Abrão de Oliveira P., I. C. Casanova Turatti & D. C. Córdoba, C. Höcht & C. A. Taira. 2007. Evaluación Rodrígues de Oliveira. 2006. Comparative analysis farmacológica en relación al perfil fotoquímico del of triterpenoids from Mikania cordifolia collected decocto de flores de Chiliotrichum diffusum from four different locations. Rev. Bras. Ci. Farm. 42: (Asteraceae). Blacpma 6: 315-316. 547-552. Alonso J. 2004. Tratado de fitofármacos y nutracéuticos. Abreu I. N., A. L. M. Porto, A. J. Marsaioli & P. Ed. Corpus, Rosario. Mazzafera. 2004. Distribution of bioactive substances Alonso J. & C. Desmarchelier. 2006. Plantas medicinales from Hypericum brasiliense during plant growth. Pl. autóctonas de la Argentina. Bases científicas para Sci. 167: 949-954. su aplicación en atención primaria de la salud. Abreu I. N., M. G. Reis, A. J. Marsaioli & P. Mazzafera. Ediciones Fitociencia, Capital Federal. 2003. Essential oil composition of Hypericum Alonso J. & C. Desmarchelier. 2007. Maytenus ilicifolia brasiliense choise. Flav. Frag. J. 19: 80-82. Martius (Congorosa). Blacpma 6: 11-22. Abu Ziada M. E., E. F. el-Halawany, I. A. Mashaly & G. Alves T. M., H. Kloos & C. L. Zani. 2003. Eleutherinone, F. Masoud. 2008. Autoecology and phytochemistry a novel fungitoxic naphthoquinone from Eleutherine of genus Amaranthus in the Nile Delta. Egypt. Asian bulbosa (Iridaceae). Mem. Inst. Oswaldo Cruz, Rio J. Pl. Sci. 7: 119-129. de Janeiro 98: 709-712. Aganga A. A., U. J. Omphile, T. Thema & L. Z. Wilson. Amaral F. M. M., M. N. S. Ribeiro, J. M. Barbosa-Filho, 2004. Chemical composition of Ryegrass (Lolium A. S. Reis, F. R. F. Nascimento & R. O. Macedo. multiflorum) at different stages of growth and Ryegrass 2006. Plants and chemical constituents with silages with additives. J. Biol. Sci. 4: 645-649. giardicidal activity. Rev. Bras. Farmacogn. 16 (Supl.): Agnese A. M., S. Núñez Montoya, L. Ariza Espinar & J. 696-720. L. Cabrera. 1999. Chemotaxonomic features in Ambrozin A. R. P., A. C. Leite, F. C. Bueno, P. C. Vieira, Argentinian species of Flaveria (Compositae). J. B. Fernándes, O. C. Bueno, M. F. das G. Fernandes Biochem. Syst. & Ecol. 27: 739-742. da Silva, F. C. Pagnocca, M. J. A. Hebling & M. Agostini F., A. C. Santos, M. Rossato, M. R. Pansera, F. Bacci Jr. 2006. Limonoids from andiroba oil and Zattera, R. Wasun & L. A. Serafini. 2005. Estudo do Cedrela fissilis and their insecticidal activity. J. Braz. óleo essencial de algumas espécies do gênero Chem. Soc. 17: 542-547. Baccharis (Asteraceae) do sul do Brasil. Rev. Bras. Amorín J. L. & R. A. Rossow. 1989-92. Guía taxonómica Farmacogn. 15: 215-220. con plantas de interés farmacéutico. Dominguenzia 7 Agra M. F., G. S. Baracho, K. Nurit, I. J. L. Basílio & V. (1): 31-38; 8(1): 28-33; 9 (1) 54-62; 10 (1): 35-40. P. M. Coelho. 2007. Medicinal and poisonous Amorín J. L. 1980-1981. Guía taxonómica con plantas de diversity of the flora of «Cariri Paraibano», Brazil. J. interés farmacéutico. Rev. INFYB 3 (5-6): 7-28; 4 (7- Ethnopharmacol. 111: 383-395. 8): 95-112; 4 (9): 193-207; 4 (10):245-259. Akaike S., M. Sumino, T. Sekine, S. Seo, N. Kimura & F. Anjos P. J. C. , P. R. Pereira, A. R. Antoniolli & M. R. V. Ikegami. 2003. A new ent-clerodane diterpene from Santos. 2006. Cardiovascular effects of the aqueous the aerial parts of Baccharis gaudichaudiana. Chem. extract of Bauhinia forficata (Caesalpiniaceae) leaves Pharm. Bull. (Tokyo) 51:197-199. in normotensive and Goldblatt hipertensive rats. XXI Albrecht R., A. Gurni & G. Bassols. 2007. Estudio Reunião Anual da Federação de Sociedades de micrográfico de tres especies pertenecientes a la Biologia Experimental, Produtos Naturais. P. 44.058. família Verbenaceae empleadas en medicina popular São Paulo, Brasil. Argentina. Blacpma 6: 179-180. Apel M. A., V. L. Sardá Ribeiro, S. A. L. Bordignon, A. Albuquerque U. P. de, P. M. de Medeiros, A. L. S. de T. Henriques & G. von Poser. 2009. Chemical Almeida, J. M. Monteiro, E. M. de Freitas Lins Neto, composition and toxicity of the essential oils from J. G. de Melo & J. P. dos Santos. 2007. Medicinal Cunila species (Lamiaceae) on the cattle tick plants of the caatinga (semi-arid) vegetation of NE Rhipicephalus (Boophilus) microplus. Parasitol. Res. Brazil: A quantitative approach. J. Ethnopharmacol. DOI 10.1007/s00436-009-1455-4. Published on line 114: 325-354. 07 May 2009. BARBOZA, G. E. et al. Medicinal flora of Argentina 335

Apel M. A., M. Sobral, E. Schapoval, A. T. Henriques, Awaad A. S. 2006. Phenolic glycosides of Juncus acutus C. Menut & J.-M. Bessiere 2004. Chemical and its anti-eczematic activity. Chem. Nat. Comp. composition of the essential oils of Eugenia 42: 152-155. beaurepaireana and Eugenia pyriformis: Section Badilla B., F. Chaves, G. Mora & L. J. Poveda. 2006. Dichotomae. J. Essent. Oil Res. 16: 191-192. Edema induced by Bothrops asper (Squamata: Arambarri A. M., S. Freire, M. Colares, N. D. Bayón, M. Viperidae) snake venom and its inhibition by Costa C. Novoa, C. Monti & S. A. Stenglein. 2006. Leaf Rican plant extracts. Rev. Biol. Trop. 54: 245-252. anatomy of medicinal shrubs and trees from gallery Baelmans R., E. Deharo, G. Bourdy, V. Muñoz, C. forests of the Paranaense province (Argentina). Part Quenevo, M. Sauvain & H. Ginsburg. 2000. A search I. Bol. Soc. Argent. Bot. 41: 223-268. for natural bioactive compounds in Bolivia through a Arambarri A. M., S. Freire, M. Colares, N. D. Bayón, M. multidisciplinary approach. Part IV. Is a new haem C. Novoa, C. Monti & S. A. Stenglein. 2008. Leaf polymerisation inhibition test pertinent for the anatomy of medicinal shrubs and trees from Misiones detection of antimalarial natural products? J. forests of the Paranaense province (Argentina). Part Ethnopharmacol. 73: 271-275. 2. Bol. Soc. Argent. Bot. 43: 31-60. Bailac P. N., A. D. Dellacasa, H. O. Bernasconi, N. Firpo Arbo M. M. & S. G. Tressens (eds.). 2002. Flora del & M. I. Ponzi. 2000. Composición del aceite esencial Iberá. EUDENE, Corrientes. y actividad antimicrobiana de Eupatorium patens. Bol. Arenas P. 1981. Etnobotánica Lengua-Maskoy. FECIC, Soc. Chil. Quim. 45: 207-211. Buenos Aires. Bakir M., P. C. Facey, I. Hassan, W. H. Mulder & R. B. Arenas P. 1983. Nombres y usos de las plantas por los Porter. 2004. Mikanolide from Jamaican Mikania indígenas Maká del Chaco Boreal. Parodiana 2: 131- micrantha. Acta Cryst. C 60: 798-800. 229. Baldizán A., C. Domínguez, D. E. 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APPENDIX III Endemic species of the medicinal flora of Argentina (Family: Nº endemics)

Asteraceae: 36 Artemisia echegarayi Hieron. Artemisia mendozana DC. var. mendozana Artemisia mendozana var. paramilloënsis F. A. Roig & Ambrosetti Baccharis artemisioides Hook. & Arn. Baccharis gilliesii A. Gray Baccharis triangularis Hauman Chersodoma argentina Cabrera Chiliophyllum densifolium Phil. Chuquiraga avellanedae Lorentz Dolichlasium lagascae D. Don Eupatorium artemisiifolium Griseb. Eupatorium ceratophyllum Hook. & Arn. Flourensia oolepis S. F. Blake Gaillardia cabrerae Covas Gochnatia glutinosa (D. Don) Hook. & Arn. Gutierrezia gilliesii Griseb. Helenium argentinum Ariza Helenium donianum (Hook. & Arn.) Seckt Hieracium tandilense Sleumer Hypochaeris pampasica Cabrera Microliabum candidum (Griseb.) H. Rob. Mutisia retrorsa Cav. Mutisia saltensis Cabrera Ophryosporus axilliflorus (Griseb.) Hieron. Ophryosporus charua (Griseb.) Hieron. Proustia cuneifolia var. mendocina (Phil.) Ariza Senecio cremeiflorus Mattf. Senecio leucostachys Baker Senecio pogonias Cabrera Senecio pseudotites Griseb. Senecio uspallatensis Hook. & Arn. Tagetes argentina Cabrera Tagetes mendocina Phil. Trichocline boecheri Cabrera Trichocline plicata D. Don ex Hook. & Arn. Trichocline sinuata (D. Don) Cabrera

Fabaceae: 9 Adesmia inflexa Griseb. Dalea elegans Gillies ex Hook. & Arn. var. elegans Mimosa rocae Lorentz & Niederl. Prosopis alpataco Phil. var. alpataco fo. alpataco Prosopis caldenia Burkart Senna kurtzii (Harms) H. S. Irwin & Barneby Senna pendula var. eriocarpa (Griseb.) H. S. Irwin & Barneby Senna subulata (Griseb.) H. S. Irwin & Barneby Sophora linearifolia Griseb. BARBOZA, G. E. et al. Medicinal flora of Argentina 363

Malvaceae: 6 Lecanophora ameghinoi (Speg.) Speg. Sphaeralcea brevipes (Phil.) Krapov. Sphaeralcea cordobensis Krapov. Sphaeralcea mendocina Phil. Sphaeralcea miniata (Cav.) Spach Sphaeralcea philippiana Krapov.

Verbenaceae: 5 Acantholippia seriphioides (A. Gray) Moldenke Glandularia hookeriana Covas & Schnack Lippia grisebachiana Moldenke Lippia junelliana (Moldenke) Tronc. Lippia turbinata fo. magnifolia Moldenke

Apiaceae: 4 Eryngium agavifolium Griseb. Gymnophyton polycephalum (Gillies & Hook.) Clos Mulinum echinus DC. Mulinum famatinense H. Wolff

Chenopodiaceae: 4 Atriplex cordobensis Gand. & Stuck. subsp. cordobensis Atriplex crenatifolia Chodat & Wilczek Atriplex lampa (Moq.) D. Dietr. Atriplex undulata (Moq.) D. Dietr.

Euphorbiaceae: 4 Cnidoscolus loasoides (Pax) I.M. Johnst. Croton saltensis Griseb. Euphorbia schickendantzii Hieron. Stillingia patagonica (Speg.) Pax & K. Hoffm.

Polygalaceae: 4 Bredemeyera colletioides (Phil.) Chodat Bredemeyera microphylla (Griseb.) Hieron. var. microphylla Monnina lorentziana Chodat Polygala stenophylla A. Gray

Amaranthaceae: 2 Gomphrena mendocina (Phil.) R. E. Fr. Gomphrena pulchella subsp. rosea (Griseb.) Pedersen

Anacardiaceae: 2 Schinus bumelioides I. M. Johnst. Schinus johnstonii F. A. Barkley

Apocynaceae: 2 Asclepias flava Lillo Morrenia stuckertiana (Kurtz ex H. Heger) Malme 364 Tomo 34 (1-2): 7-365. 2009 KURTZIANA

Berberidaceae: 2 Berberis grevilleana Gillies ex Hook. & Arn. Berberis lilloana Job

Celastraceae: 2 Maytenus cuezzoi Legname Moya spinosa Griseb.

Gentianaceae: 2 Gentianella parviflora (Griseb.) T. N. Ho Gentianella imberbis (Griseb.) Filippa & Barboza

Ledocarpaceae: 2 Balbisia aphanifolia (Griseb.) Hunz. & Ariza Balbisia calycina (Griseb.) Hunz. & Ariza

Oxalidaceae: 2 Oxalis subacaulis Gillies ex Hook. & Arn. Oxalis yacutulensis R. Knuth

Plantaginaceae: 2 Monttea aphylla (Miers.) Benth. & Hook. var. aphylla Plantago tandilensis (Pilg.) Rahn

Rosaceae: 2 Acaena myriophylla Lindl. Polylepis australis Bitter

Solanaceae: 2 Fabiana peckii Niederl. Grabowskia obtusa Arn.

Valerianaceae: 2 Valeriana ferax (Griseb.) Höck Valeriana polybotrya (Griseb.) Höck

Zygophyllaceae: 2 Larrea cuneifolia Cav. Plectrocarpa tetracantha Gillies ex Hook. & Arn.

Amaryllidaceae: 1 Rhodophiala mendocina (Phil.) Ravenna

Boraginaceae: 1 Ehretia cortesia Gottschling

Brassicaceae: 1 Lepidium argentinum Thell. BARBOZA, G. E. et al. Medicinal flora of Argentina 365

Buddlejaceae: 1 Buddleja cordobensis Griseb.

Cactaceae: 1 Maihueniopsis darwinii var. hickenii (Britton & Rose) R. Kiesling

Caryophyllaceae: 1 Pycnophyllum convexum Griseb.

Celtidaceae: 1 Celtis pallida Torr. var. pallida

Convolvulaceae: 1 Ipomoea hieronymi (Kuntze) O’Donell var. hieronymi

Cyperaceae: 1 Cyperus spectabilis var. jujuyensis Kük.

Ephedraceae: 1 Ephedra ochreata Miers

Iridaceae: 1 Sisyrinchium macrocarpum Hieron.

Lamiaceae: 1 Minthostachys verticillata (Griseb.) Epling

Malpighiaceae: 1 Tricomaria usillo Hook. & Arn.

Martyniaceae: 1 Ibicella parodii Abbiatti

Myrtaceae: 1 Siphoneugena occidentalis D. Legrand

Rhamnaceae: 1 Condalia microphylla Cav.

Rubiaceae: 1 Galium lilloi Hicken

Violaceae: 1 Hybanthus serratus (Phil.) Hassl.