Terpenoids and Glycosides

The terpenoids are a large and diverse class of naturally occurring organic chemicals, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. They can be classified according to the number of isoprene units used: Hemiterpenoids, Monoterpenoids, Sesquiterpenoids, Diterpenoids, Sesterterpenoids, Triterpenoids, Tetraterpenoids. These lipids can be found in all classes of living things, and are the largest group of natural products. Plant terpenoids are used extensively for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes.

www.MedChemExpress.com 1 Terpenoids and Glycosides Inhibitors & Modulators

(+)-Borneol (+)-Camphor (d-Borneol) Cat. No.: HY-N1368A (D-(+)-Camphor; (1R)-(+)-Camphor) Cat. No.: HY-B1173

(+)-Borneol (d-Borneol) is a natural bicyclic (+)-Camphor is an ingredient in cooking, and as an monoterpene used for analgesia and anesthesia in embalming fluid for medicinal purposes,. traditional Chinese medicine; enhances GABA

receptor activity with an EC50 of 248 μM.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 100 mg Size: 10 mM × 1 mL, 500 mg

(+)-Dehydroabietic acid (+)-Longifolene Cat. No.: HY-N2546 Cat. No.: HY-N6662

(+)-Dehydroabietic acid is a diterpenoid. (+)-Longifolene is a sesquiterpenoid and a (+)-Dehydroabietic acid can be used for the metabolite in rabbits. (+)-Longifolen is converted acrylamide Hydrogel synthesis. to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 25 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

(+)-trans-Isolimonene (-)-Altenuene Cat. No.: HY-N7250 Cat. No.: HY-N6713

(+)-trans-Isolimonene is a natural monoterpene (-)-Altenuene is a heptaketide isolated from an isolated from essential oil. endolichenic fungal strain Nigrospora sphaerica.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg

(-)-Borneol (-)-Cedrene (L-Borneol) Cat. No.: HY-N1368B (α-cedrene) Cat. No.: HY-135190

(-)-Borneol has a highly efficacious positive (-)-Cedrene (α-cedrene) is a sesquiterpene

modulating action at GABA receptor with an EC50 constituent of cedarwood oils, with anti-leukemic, of 237 μM. antimicrobial and anti-obesity activities.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 1 mL, 5 mL

(-)-Fenchone (-)-Limonene Cat. No.: HY-N5132 ((S)-(-)-Limonene) Cat. No.: HY-Z0478

(-)-Fenchone, a bicyclic monoterpene, is widely (-)-Limonene ((S)-(-)-Limonene) is a monoterpene distributed in plants and found in essential oils found in many pine-needle oils and in turpentine. from Thuja occidentalis. (-)-Limonene can induce a mild bronchoconstrictive effect.

Purity: >98.0% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 500 mg Size: 10 mM × 1 mL, 100 mg

2 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

(-)-Menthol (-)-α-Pinene Cat. No.: HY-75161 Cat. No.: HY-N0549

(-)-Menthol is a key component of peppermint oil (-)-α-Pinene is a monoterpene and shows sleep that binds and activates transient receptor enhancing property through a direct binding to potential melastatin 8 (TRPM8), a GABAA-benzodiazepine (BZD) receptors by acting as Ca2+-permeable nonselective cation channel, to a partial modulator at the BZD binding site. 2+ increase [Ca ]i. Antitumor activity.

Purity: >98.0% Purity: 99.63% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg, 1 g Size: 10 mM × 1 mL, 100 mg, 1 g, 5 g

(-​)​-​α-​Terpineol (20R)-Ginsenoside Rh1 ((S​)​-​α-​Terpineol) Cat. No.: HY-N1467 Cat. No.: HY-N1400

(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene (20R)-Ginsenoside Rh1, the R isomer of Ginsenoside compound, is one of important aroma compounds in Rh1 isolated from Panax Ginseng, inhibits the white wines. thrombin-induced conversion of fibrinogen to fibrin.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

(20R)-Protopanaxadiol (R)-(+)-Citronellal Cat. No.: HY-N2040 ((+)-Citronellal) Cat. No.: HY-111664

(20R)-Protopanaxadiol is a triterpenoid saponin (R)-(+)-Citronellal, isolated from citrus, metabolite of 20(R)-ginsenoside Rg3 in black lavender and eucalyptus oils, is a monoterpenoid ginseng. (20R)-Protopanaxadiol exhibits anti-tumor and main component of citronellal oil with a activity and cytotoxicity, and potently inhibits distinct lemon scent. A flavouring agent. Used for the growth of Helicobacter pylori. insect repellent and antifungal properties.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

(R)-Citronellol (Rac)-β-Chamigrenic acid (D-Citronellol; (R)-(+)-β-Citronellol) Cat. No.: HY-124257 Cat. No.: HY-N7606

(R)-Citronellol (D-Citronellol) is an alcoholic (Rac)-β-Chamigrenic acid is a racemate of monoterpene found in geranium essential oil. β-Chamigrenic acid. β-Chamigrenic acid is an (R)-Citronellol inhibits degranulation of mast sesquiterpenoid isolated from S.chinensis. cells and does not affect caffeine bitterness perception.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 1 mg

(S)-(−)-Perillyl alcohol (S)​-​(-​)​-​Citronellal Cat. No.: HY-116514 ((-​)​-​Citronellal) Cat. No.: HY-111664A

(S)-(−)-Perillyl alcohol is a monoterpene found in (S)-(-)-Citronellal ((-)-Citronellal) is a lavender, inhibits farnesylation of Ras, monoterpenoid compound found in Corymbia upregulates the mannose-6-phosphate receptor and citriodora and Cymbopogon nardus essential oils. induces apoptosis. Anti-cancer activity.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: Size: 10 mM × 1 mL, 100 mg Size: 1 mg, 5 mg

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1,4-Cineole 10-Deacetylbaccatin III Cat. No.: HY-N7117 Cat. No.: HY-16565

1,4-Cineole is a widely distributed, natural, 10-Deacetylbaccatin-III is an intermediate for oxygenated monoterpene. 1,4-Cineole, present in taxol analog preparations. IC50 value: Target: eucalyptus oil, activates both human TRPM8 and Taxols have exhibit antitumor agents. Several of human TRPA1. these taxols can be synthesized from 10- Deacetylbaccatin-III.

Purity: >95.0% Purity: 95.05% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 10 mM × 1 mL, 100 mg, 200 mg, 500 mg

11-oxo-mogroside V 11-Oxomogroside IIe Cat. No.: HY-N0501 Cat. No.: HY-N6852

11-oxo-mogroside V is a natural sweetener, 11-Oxomogroside IIe is a triterpene glycoside isolated from the fruits of Momordica isolated from Siraitia grosvenori. grosvenori, exhibits strong antioxidant activity.

Purity: 99.69% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg Size: 5 mg, 10 mg

11-​Keto-​beta-​boswellic acid 11-​Oxomogroside III (11-Keto-β-boswellic acid) Cat. No.: HY-N2056 Cat. No.: HY-N6921

11-Keto-beta-boswellic acid (11-Keto-β-boswellic 11-Oxomogroside III is a cucurbitane triterpene acid) is a pentacyclic triterpenic acid of the glycoside isolated from in Siraitia grosvenorii oleogum resin from the bark of the Boswellia fruits. serrate tree, popularly known as Indian Frankincense.

Purity: 99.96% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

12-Hydroxyganoderic Acid D 14-Deoxy-11,12-didehydroandrographolide Cat. No.: HY-N7021 (14-dehydro Andrographolide; AP10) Cat. No.: HY-N1490

12-Hydroxyganoderic Acid D is a triterpenoid 14-Deoxy-11,12-didehydroandrographolide is an extracted from Ganoderma lucidum. analogue of Andrographolide that can be isolated from A. paniculata. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.

Purity: >98% Purity: 99.55% Clinical Data: Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg

15-Acetyl-deoxynivalenol 16α-Hydroxydehydrotrametenolic acid Cat. No.: HY-N6683 (3β,16α-Dihydroxylanosta-7,9(11),24-trien-21-oic acid) Cat. No.: HY-N2990

15-Acetyl-deoxynivalenol is a highly toxic 16α-Hydroxydehydrotrametenolic acid is a trichothecene found in cereals, and a metabolite triterpene Acid in fermented mycelia of edible of deoxynivalenol, exhibits toxicity to HepG2 fungus Poria cocos. cells.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

4 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

18β-Glycyrrhetinic acid 2,2'-Anhydrouridine Cat. No.: HY-N0180 (2,2'-Cyclouridine; O2,2'-Cyclouridine) Cat. No.: HY-W012313

18β-Glycyrrhetinic acid is the major bioactive 2,2'-Anhydrouridine is used for anticancer and component of Glycyrrhizae Radix and possesses antiviral research. anti-ulcerative, anti-inflammatory and antiproliferative properties.

Purity: 99.63% Purity: >98.0% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg, 5 g Size: 10 mM × 1 mL, 100 mg

20(R)-Ginsenoside Rg2 20(R)-Ginsenoside Rg3 Cat. No.: HY-N2039 (20(R)-Propanaxadiol; R-ginsenoside Rg3) Cat. No.: HY-N1376

20(R)-Ginsenoside Rg2, isolated from Ginseng stems 20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol), one and leaves, shows inhibitory effects on lung of the active compounds present in ginseng root, cancer NCI-H1650 cells. Anti-cancer activities. has a potent angiosuppressive and antitumor activities.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

20(R)-Ginsenoside Rh2 20(R)-Notoginsenoside R2 Cat. No.: HY-N1401 Cat. No.: HY-N2049

20(R)-Ginsenoside Rh2, a matrix 20(R)-Notoginsenoside R2 is an isolated metalloproteinase (MMP) inhibitor, acts as a notoginsenoside from Panax notoginseng. cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 5 mg, 10 mg

20(S),24(R)-Ocotillol 20(S)-Ginsenoside Rg3 Cat. No.: HY-N6262 (20(S)-Propanaxadiol; S-ginsenoside Rg3) Cat. No.: HY-N0603

20(S),24(R)-Ocotillol is isolated from Panax 20(S)-Ginsenoside Rg3 is the main component of Red ginseng. ginseng. Ginsenoside Rg3 inhibits Na+ and

hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20(S)-Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression. Purity: >98% Purity: 98.10% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

20-Deoxyingenol 20-Hydroxyganoderic Acid G Cat. No.: HY-N0866 Cat. No.: HY-N7018

20-Deoxyingenol is a natural compound. 20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia

cells activated by LPS with an IC50 of 21.33 μM.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

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20-O-Acetylingenol-3-angelate 21-​O-​Tigloylgymnemagenin (Euphorbia factor Pe1) Cat. No.: HY-N0868 Cat. No.: HY-N2275

20-O-Acetylingenol-3-angelate is a natural 21-​O-​Tigloylgymnemagenin (Compound 7) is a compound. acylated triterpenes isolated from Gymnema sylvestre.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

23-Hydroxylongispinogenin (12-Oleanene-3β,16β,23,28-tetrol; 25-O-Methylalisol A 3β,16β-12-Oleanene-3, 16,23,28-tetrol) Cat. No.: HY-N2274 Cat. No.: HY-N6993

23-Hydroxylongispinogenin 25-O-Methylalisol A is a protostane triterpenoids (12-Oleanene-3β,16β,23,28-tetrol) is extracted isolated from Alisma orientale. from Lysimachia heterogenea Klatt. Lysimachia heterogenea Klatt is a perennial herb, which is used as a folk medicine in subduing swelling and detoxicating in China. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

26-Deoxycimicifugoside 27-Deoxyactein Cat. No.: HY-N5088 Cat. No.: HY-N6264

26-Deoxycimicifugoside is a triterpene xylosides 27-Deoxyactein is a constituent isolated from isolated from Cimicifuga racemosa. Cimicifuga racemosa, prevents TCDD-induced osteoblasts damage. 27-Deoxyactein inhibits increased AhR, CYP1A1 and ERK levels.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

28-Demethyl-β-amyrone 3,29-Dibenzoyl rarounitriol (28-​Norolean-​12-​en-​3-​one) Cat. No.: HY-N7003 Cat. No.: HY-N0357

28-Demethyl-β-amyrone (28-Norolean-12-en-3-one) is 3,29-Dibenzoyl rarounitriol is one major bioactive one of the main triterpenes from Pistacia lentiscus compound of multiflorane triterpene esters var. Chia. 28-Demethyl-β-amyrone is an antitoxin Trichosanthes kirilowii, can be chosen as the and can effectively for the toxic effects of marker for quantitation of Trichosanthes Staphylococcal enterotoxins (SEs). kirilowii.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

3,29-O-Dibenzoyloxykarounidiol 3-Acetyl-beta-boswellic acid (Karounidiol dibenzoate) Cat. No.: HY-N7691 Cat. No.: HY-N2075

3,29-O-Dibenzoyloxykarounidiol (Karounidiol 3-Acetyl-beta-boswellic acid is a boswellic acid dibenzoate) is a triterpene benzoate isolated from isolated from Boswellia serrata gum resin. the fruit of Momordica grosvenori.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg Size: 1 mg, 5 mg

6 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

3-Carene 3-Dehydrotrametenolic acid Cat. No.: HY-N6663 Cat. No.: HY-N2177

3-Carene is a bicyclic monoterpene in essential 3-​Dehydrotrametenolic acid, isolated from the oils extracted from pine trees. 3-Carene inhibits sclerotium of Poria cocos, is a lactate dehydrogenase nociceptive stimulus-induced inflammatory (LDH) inhibitor. 3-​Dehydrotrametenolic acid infiltrates and COX-2 overexpression, and with promotes adipocyte differentiation in vitro and acts antinociceptive effect. as an insulin sensitizer in vivo.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

3-Epioleanolic acid 3-Epiursolic Acid Cat. No.: HY-N4290 Cat. No.: HY-N4289

3-Epioleanolic acid is an active component of 3-Epiursolic Acid is a triterpenoid isolated from Verbena officinalis Linn, with anti-inflammatory Myrtaceae, acts as a competitive inhibitor of activity. cathepsin L (ICIC50, 6.5 μM; Ki, 19.5 μM), with no obvious effect on cathepsin B.

Purity: >98% Purity: 99.20% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

3-O-Acetyl-16α-hydroxytrametenolic acid 3-O-Beta-D-Glucopyranosylplatycodigenin Cat. No.: HY-N2994 Cat. No.: HY-N3523

3-O-Acetyl-16α-hydroxytrametenolic acid (Compound 3-O-Beta-D-Glucopyranosylplatycodigenin is an 3) is a triterpene found in Poria cocos, with oleanane-type triterpenoid isolated from roots of anti-oxidant and anti-cancer activity. Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell

line with an IC50 of 13.36 μM. Purity: 99.23% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg Size: 1 mg, 5 mg

3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-ene-23(21)- 31-Norlanostenol lactone Cat. No.: HY-N4162 Cat. No.: HY-N7267 3-Oxo-21α-methoxy-24,25,26,27-tetranortirucall-7-e 31-Norlanostenol is a triterpenic compound ne-23(21)-lactone is a cytotoxic tirucallane C26 isolated from the latex of Euphorbia triterpenoid isolated from the stem barks of officinarum. 31-Norlanostenol can act as Aphanamixis grandifolia. efficient insect growth regulator on S. frugiperda and Tenebrio molitor.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

3α-Hydroxymogrol 4-Aza-Oleanolic acid methyl ester Cat. No.: HY-N6913 Cat. No.: HY-18005

3α-Hydroxymogrol is a triterpenoid isolated from 4-Aza-Oleanolic acid methyl ester is a triterpenic Siraitia grosvenorii Swingle, acts as a potent derivative. AMPK activator, and enhances AMPK phosphorylation.

Purity: 98.47% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

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5,15-Diacetyl-3-benzoyllathyrol 5,6-Didehydroginsenoside Rd (Euphorbia factor L3) Cat. No.: HY-N0562 Cat. No.: HY-N4263

5,15-Diacetyl-3-benzoyllathyrol is one of the 5,6-Didehydroginsenoside Rd is a dammarane-type lathyrane diterpenoids, that has anti-cancer saponin isolated from the dried roots of Panax activity. notoginseng.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg, 10 mg Size: 1 mg, 5 mg

6'-O-beta-D-Glucosylgentiopicroside 6'-​O-​Cinnamoyl harpagide Cat. No.: HY-N2100 Cat. No.: HY-N4221

6'-O-beta-D-Glucosylgentiopicroside is a 6'-O-Cinnamoyl harpagide is an iridoid glycoside secoiridoid isolated from the roots of G. isolated from the roots of Scrophularia ningpoensis. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

7-epi-Taxol 7-O-Geranylscopoletin (7-epi-Paclitaxel) Cat. No.: HY-N0227 (7-Geranyloxy-6-methoxycoumarin) Cat. No.: HY-N2746

7-epi-Taxol is an active metabolite of taxol, with 7-O-Geranylscopoletin is a coumarin from the root activity comparable to that of taxol against cell of Atalantia monophylla. Various parts of this replication, promoting microtubule bundle plant have been used for folk medicine for several formation and against microtubule purposes such as chronic rheumatism, paralysis, depolymerization. antispasmodic, stimulant and hemiplegia.

Purity: 99.75% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg Size: 1 mg

7-O-Methyl morroniside 7-O-Methylaloeresin A Cat. No.: HY-N6008 Cat. No.: HY-N2214

7-O-Methyl morroniside is an iridoid glycoside 7-O-Methylaloeresin A is 5-methylchromone (IG) extracted from Cornus officinalis fructus, used glycoside isolated from Commiphora socotrana in many traditional Chinese medicines. (Burseraceae).

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

7-xylosyltaxol 7beta-Hydroxylathyrol (7-Xylosylpaclitaxel; Taxol-7-xyloside) Cat. No.: HY-77574 Cat. No.: HY-N1484

7-xylosyltaxol(Taxol-7-xyloside) is a taxol 7beta-Hydroxylathyrol is a natural product. (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

8 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

8(14)-Abietenic acid 8-Epidiosbulbin E acetate Cat. No.: HY-133615 Cat. No.: HY-N7047

8(14)-Abietenic acid is an abietane diterpenoid. 8-Epidiosbulbin E acetate, a furanoid, is abundant Abietenic acid is racemic of 8(14)-Abietenic acid. in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate Abietenic acid acts as a PPARα/γ dual activator. exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg, 10 mg, 25 mg

8-​O-​Acetylharpagide 9-cis-Retinal Cat. No.: HY-N0757 Cat. No.: HY-W009310

8-O-Acetylharpagide is an iridoid isolated from 9-cis-Retinal is a natural retinoid. Dietary Ajuga reptans with antitumoral, antiviral, 9-cis-β-carotene generates 9-cis-retinoids via antibacterial, and anti-inflammatory activities. cleavage into 9-cis-retinal. 9-cis Retinal binds 8-O-Acetylharpagide also has a biological activity to cellular retinol-binding protein-I (CRBP-I) and on isolated smooth muscle preparations from guinea CRBP-II with Kds of 8 nM and 5 nM, respectively. pig. Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg

Abietic acid Acanthopanaxoside B Cat. No.: HY-N6871 Cat. No.: HY-N4135

Abietic acid, a diterpene isolated from Pimenta Acanthopanaxoside B is a triterpenoid saponin racemosa var. grissea, possesses isolated from the leaves of Acanthopanax senticosus. antiproliferative, antibacterial, and anti-obesity properties. Abietic acid inhibits lipoxygenase activity for allergy treatment.

Purity: >81.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg Size: 5 mg

Acevaltrate Actein Cat. No.: HY-N2070 Cat. No.: HY-N6872

Acevaltrate, isolated from Valeriana Actein is a triterpene glycoside isolated from the glechomifolia, inhibits the Na+/K+-ATPase rhizomes of Cimicifuga foetida. Actein activity in the rat kidney and brain hemispheres suppresses cell proliferation, induces autophagy with IC50s of 22.8±1.1 μM and 42.3±1.0 μM, and apoptosis through promoting ROS/JNK respectively. activation, and blunting AKT pathway in human bladder cancer. Actein has little toxicity in vivo. Purity: 99.56% Purity: 98.58% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg Size: 5 mg

Agnuside Ajugol (Agnoside) Cat. No.: HY-N2518 Cat. No.: HY-N0914

Agnuside is a compound isolated from Vitex negundo, Ajugol is an iridoid glycoside that can be down-regulates pro-inflammatory mediators PGE2 isolated from Sideritis germanicopolitana. and LTB4, and reduces the expression of Ajugol has anti-protozoal activity againt cytokines, with anti-arthritic activity. Trypanosoma b. rhodesiense with an IC50 of 31.8 μg/mL.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

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AKBA Alantolactone (Acetyl-11-keto-β-boswellic acid) Cat. No.: HY-N0892 ((+)-Alantolactone; Alant camphor; Inula camphor) Cat. No.: HY-N0038

AKBA (Acetyl-11-keto-β-boswellic acid) is an Alantolactone is a selective STAT3 inhibitor, active triterpenoid compound from the extract of with potent anticancer activity. Alantolactone Boswellia serrate and a novel Nrf2 activator. induces apoptosis in cancer.

Purity: 99.71% Purity: 99.94% Clinical Data: Phase 2 Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Albiflorin Alismoxide Cat. No.: HY-N0037 ((+)-Alismoxide) Cat. No.: HY-N0426

Albiflorin is a major constituent contained in Alismoxide is a natural product. peony root; possesses therapeutic potential for neurodegenerative diseases.

Purity: >98.0% Purity: 95.27% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 10 mg

Alisol B Alisol B 23-acetate (23-Acetylalismol B; 23-O-Acetylalisol B; Cat. No.: HY-N0805A Alisol B monoacetate) Cat. No.: HY-N0805

Alisol B is a potentially novel therapeutic Alisol B 23-acetate (23-Acetylalismol B), a compound for bone disorders by targeting the natural triterpenoid, produces protective effects differentiation of osteoclasts as well as their against EE-induced cholestasis, due to functions. FXR-mediated gene regulation. IC50 Value: Target: Anti-hepatotoxic natural product.

Purity: >98% Purity: 99.84% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Alisol C 23-acetate Alisol F (23-O-Acetylalisol C; Alisol C monoacetate) Cat. No.: HY-N0856 Cat. No.: HY-N0854

Alisol C 23-acetate, a natural product extracted Alisol F is a triterpene isolated from Alisma from Alisma orientale, can significantly and orientalis, has immunosuppressive and anti-virus strongly inhibit DTH response after oral functions. Alisol F exhibits inhibitory activity administration. in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the HepG2.2.15 cell

line with an IC50 of 0.6 μM. Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Alisol G alpha-Bisabolol (Alisol-G; 25-Anhydroalisol A) Cat. No.: HY-N0855 Cat. No.: HY-121222

Alisol G is a natural product extracted from alpha-Bisabolol is a nontoxic sesquiterpene Rhizoma Alismatis. alcohol present in natural essential oil, with anticancer activity.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg Size: 1 mg, 5 mg

10 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

alpha-Boswellic acid alpha-Cyperone (α-Boswellic acid) Cat. No.: HY-N0611 (α-Cyperone; (+)-α-Cyperone) Cat. No.: HY-N0710 alpha-Boswellic acid (α-Boswellic acid) is a alpha-Cyperone (α-Cyperone) is associated with the pentacyclic triterpene compound from extracts of down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Frankincense, has anticonvulsant and anti-cancer Rac1, resulting in reduction of inflammation, properties. which would be highly beneficial for treatment of inflammatory diseases such as AD.

Purity: 98.40% Purity: 99.12% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 25 mg, 50 mg alpha-Hederin Amarogentin (α-Hederin) Cat. No.: HY-N0255 Cat. No.: HY-N2447 alpha-Hederin (α-Hederin) is a water-soluble Amarogentin is a secoiridoid glycoside that is pentacyclic triterpenoid saponin, possessing mainly extracted from Swertia and Gentiana several biological properties such as roots. Amarogentin exhibits many biological antispasmodic, moliscicidic, anthelmithic and effects, including anti-oxidative, anti-tumour, inhibiting cell proliferation. and anti-diabetic activities.

Purity: >98.0% Purity: 98.96% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Ambroxide Ammonium glycyrrhizinate Cat. No.: HY-N1384 (Monoammonium glycyrrhizinate) Cat. No.: HY-N0184B

Ambroxide is a naturally occurring terpenoid. Ammonium glycyrrhizinate is a triterpenoid Ambroxide is one of the key constituents of saponin, acting as a direct HMGB1 antagonist, ambergris. with anti-inflammatory anti-tumor, anti-diabetic activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Andrographolide Andropanoside (Andrographis) Cat. No.: HY-N0191 Cat. No.: HY-N2868

Andrographolide is a NF-κB inhibitor, which Andropanoside is a natural product isolated and inhibits NF-κB activation through covalent purified from the herbs of Andrographis paniculata. modification of a cysteine residue on p50 in Andrographis paniculata possesses a protective endothelial cells without affecting IκBα activity against various liver disorders. degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects. Purity: 98.57% Purity: >98% Clinical Data: Launched Clinical Data: No Development Reported Size: 100 mg, 500 mg Size: 1 mg, 5 mg

Araloside A Araloside V (Chikusetsusaponin IV) Cat. No.: HY-N2115 (Congmunoside V) Cat. No.: HY-N6970

Araloside A (Chikusetsusaponin IV) is a component Araloside V (Congmunoside V) is a triterpenoid of Panax japonicus, with low-renin-inhibitory saponin isolated from Aralia elata. activity, with an IC50 of 77.4 μM.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

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Araloside VII Araloside X (Congmunoside VII) Cat. No.: HY-N2002 Cat. No.: HY-N2001

Araloside VII (Congmunoside VII) is a saponin Araloside X (Congmunoside X) is a triterpenoid isolated from leaves of Aralias elate. saponin isolated from Aralia elata.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Ardisiacrispin A Arglabin (Deglucocyclamin; LTS-4; Saxifragifolin B) Cat. No.: HY-N0206 ((+)-Arglabin) Cat. No.: HY-16059

Ardisiacrispin A (Deglucocyclamin) is a common Arglabin ((+)-Arglabin), a natural product triterpenoid saponin from Ardisia species. isolated from Artemisia glabella, is a NLRP3 Ardisiacrispin A has similar biological properties inflammasome inhibitor. Arglabin shows with some triterpenoid saponins in A. anti-inflammatory and antitumor activities.

Purity: >98% Purity: 99.17% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Arjunetin Arjungenin Cat. No.: HY-N7592 Cat. No.: HY-N4294

Arjunetin, isolated from Terminalia arjuna, is Arjungenin, a triterpene isolated from an insect feeding-deterrent and growth inhibitor. Terminalia arjuna, is an insect feeding-deterrent and growth inhibitor.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg Size: 5 mg, 10 mg

Arnicolide D ArnicolideC Cat. No.: HY-N6843 Cat. No.: HY-N6842

Arnicolide D is a sesquiterpene lactone isolated ArnicolideC is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates Centipeda minima. ArnicolideC exertes a the cell cycle, activates the caspase signaling cytotoxic effect on the panel of Nasopharyngeal pathway and inhibits the PI3K/AKT/mTOR and carcinoma (NPC) cells, significantly inhibiting STAT3 signaling pathways. cell growth in a dose- and time- dependent manner.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Arnidiol Artemether (Dihydroqinghaosu methyl ether; Dihydroartemisinin Cat. No.: HY-N4165 methyl ether; SM224) Cat. No.: HY-N0402

Arnidiol is a pentacyclic triterpene isolated from Artemether is an antimalarial for the treatment of Barleria Longiflora Linn F. resistant strains of falciparum malaria. Target: Antiparasitic Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg, 500 mg

12 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Artemisic acid Artemisinin (Qing Hao acid; Artemisinic acid; Arteannuic acid) Cat. No.: HY-N1984 (Qinghaosu; NSC 369397) Cat. No.: HY-B0094

Artemisinic acid (Qing Hao acid), an amorphane Artemisinin (Qinghaosu), a sesquiterpene lactone, sesquiterpene isolated from Artemisia annua L. is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner.

Purity: 99.88% Purity: 99.03% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 200 mg, 500 mg

Asiatic acid Asiaticoside Cat. No.: HY-N0194 Cat. No.: HY-N0439

Asiatic acid, a pentacyclic triterpene found in Asiaticoside, a trisaccaride triterpene from Centella asiatica, induces apoptosis in melanoma Centella asiatica, suppresses TGF-β/Smad cells. Asiatic acid has the potential for skin signaling through inducing Smad7 and inhibiting cancer treatment. Asiatic acid also has TGF-βRI and TGF-βRII in keloid fibroblasts; anti-inflammatory activities. Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties. Purity: 99.47% Purity: 99.84% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

Asiaticoside B Asperosaponin VI Cat. No.: HY-N5052 Cat. No.: HY-N0265

Asiaticoside B is a triterpene glycoside isolated Asperosaponin VI, A saponin component from Dipsacus from Actaea asiatica, with anti-cancer activity. asper wall, induces osteoblast differentiation through BMP2/p38 and ERK1/2 pathway.

Purity: >98.0% Purity: 98.73% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Asperuloside Astaxanthin Cat. No.: HY-N1382 Cat. No.: HY-B2163

Asperuloside is an iridoid isolated from Hedyotis Astaxanthin, a red dietary carotenoid isolated diffusa, with anti-inflammatory activity. from Haematococcus pluvialis, is a modulator of Asperuloside inhibits inducible nitric oxide PPARγ and a potent antioxidant with synthase (iNOS), suppresses NF-κB and MAPK antiproliferative, neuroprotective and signaling pathways. anti-inflammatory activity.

Purity: 99.69% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Astragaloside I Astragaloside II (Astrasieversianin IV; Cyclosieversioside B) Cat. No.: HY-N0432 (Astrasieversianin VIII) Cat. No.: HY-N0433

Astragaloside I is a natural product isolated from Astragaloside II is a natural isolated from Astragalus. Astragalus. IC50 value: Target: In vitro: In vivo: The developed and validated method has been successfully applied to the quantification and pharmacokinetic study of AST II in rats after intravenous and oral administration of AST II. Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

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Astragaloside III Astragaloside IV Cat. No.: HY-N0434 Cat. No.: HY-N0431

Astragaloside III is a natural product isolated Astragaloside IV, an active component isolated from Astragalus. from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells.

Purity: 98.89% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

Atractylenolide I Atractylenolide II Cat. No.: HY-N0201 (Asterolide) Cat. No.: HY-N0202

Atractylenolide I is a sesquiterpene derived from Atractylenolide II is a sesquiterpene compound the rhizome of Atractylodes macrocephala, isolated from the dried rhizome of Atractylodes possesses diverse bioactivities, such as macrocephala (Baizhu in Chinese); neuroprotective, anti-allergic, anti-inflammatory anti-proliferative activity. and anticancer properties.

Purity: 99.08% Purity: 99.91% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Atractylenolide III Atractylone (ICodonolactone; 8β-Hydroxyasterolide) Cat. No.: HY-N0203 (Atractylon) Cat. No.: HY-N2095

Atractylenolide III is a major component of Atractylone (Atractylon) is a sesquiterpenoid Atractylodes rhizome can induce apoptosis of the extracted from Atractylodis Rhizoma. Atractylone lung carcinoma cells. (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Purity: 99.91% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg Size: 1 mg, 5 mg

Atractyloside A Atractyloside potassium salt Cat. No.: HY-N0237 Cat. No.: HY-N1462

Atractyloside A is a natural TCM reference Atractyloside potassium salt is a toxic compound. diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport.

Purity: >98.0% Purity: 99.93% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 500 μg, 1 mg, 5 mg, 10 mg

Aucubin Bacopaside II Cat. No.: HY-N0664 Cat. No.: HY-N6016

Aucubin is an iridoid glycoside with a wide range Bacopaside II, an extract from the medicinal herb of biological activities, including Bacopa monnieri, blocks the Aquaporin-1 (AQP1) anti-inflammatory, anti-microbial, anti-algesic as water channel and impairs migration of cells that well as anti-tumor activities. express AQP1. Bacopaside II induces cell cycle arrest and apoptosis.

Purity: >98.0% Purity: 98.69% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg

14 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Bacopaside V Bacoside A3 Cat. No.: HY-N4295 Cat. No.: HY-N5064

Bacopaside V is a bioactive triterpenoid glycoside Bacoside A3, a triterpenoid saponin, is one of the of Bacopa monniera, a herb having confirmed major active constituents in Bacopa monnieri. nervine tonic activity. Bacoside A3 has neuroprotective activity.

Purity: >98% Purity: 98.47% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Bakkenolide B Bakuchiol Cat. No.: HY-N7292 ((S)-(+)-Bakuchiol) Cat. No.: HY-N0235

Bakkenolide B is isolated from petasites japonicas Bakuchiol is a phytoestrogen isolated from the leaves and has anti-allergic and seeds of Psoralea corylifolia L; has anti-tumor anti-inflammatory effects. Bakkenolide B can be effects. used for the study of asthma.

Purity: >98% Purity: 99.25% Clinical Data: No Development Reported Clinical Data: Phase 2 Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Barlerin Bayogenin (8-O-Acetyl shanzhiside methyl ester) Cat. No.: HY-N0758 Cat. No.: HY-N1932

Barlerin (8-O-Acetyl shanzhiside methyl ester) is Bayogenin is an alfalfa saponin, shows moderate an iridoid glucoside isolated from the leaves of potency of glycogen phosphorylase inhibition. Lamiophlomis rotata Kudo, a Chinese folk medicinal plant in Xi-zang. Barlerin (8-O-Acetyl shanzhiside methyl ester) could inhibt NF-κB.

Purity: 99.82% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 25 mg Size: 5 mg, 10 mg, 20 mg

Bayogenin 3-O-β-D-glucopyranoside Beesioside Q Cat. No.: HY-N2601 Cat. No.: HY-125686

Bayogenin 3-O-β-D-glucopyranoside, a triterpenoid Beesioside Q is a oleanolic acid triterpene saponin isolated from Polygala japonica, possesses saponin isolated from the rhizome of Beesia anti-inflammatory activities. calthaefolia (Maxim.) Ulbr.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Benzoyloxypaeoniflorin Benzoylpaeoniflorin Cat. No.: HY-N2101 Cat. No.: HY-N0852

Benzoyloxypaeoniflorin, isolated from the root of Benzoylpaeoniflorin is a natural product; may Paeonia suffruticosa, is a tyrosinase inhibitor treat coronary heart disease by decreasing against mushroom tyrosinase with IC50 of 0.453 mM. apoptosis.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

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Bernardioside A Beta-Eudesmol Cat. No.: HY-N2606 Cat. No.: HY-N6018

Bernardioside A is a triterpenoid saponin isolated Beta-Eudesmol is a natural oxygenated

from Bellis bernardii. sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1.

Purity: >98% Purity: 96.54% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

Betulin Betulinaldehyde (Trochol) Cat. No.: HY-N0083 (Betulinic aldehyde; Betunal) Cat. No.: HY-N0084

Betulin (Trochol), is a sterol regulatory Betulinaldehyde(Betunal) belongs to pentacyclic element-binding protein (SREBP) inhibitor with an triterpenoids and was reported to exhibit

IC50 of 14.5 μM in K562 cell line. antimicrobial activities against bacteria and fungi, including S. aureus.

Purity: >98.0% Purity: 98.56% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 50 mg, 100 mg, 200 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

Betulinic acid Betulinic acid methyl ester (Lupatic acid; Betulic acid) Cat. No.: HY-10529 (Methyl betulinate) Cat. No.: HY-N6587

Betulinic acid is a natural pentacyclic Betulinic acid methyl ester, a betulinic acid triterpenoid, acts as a eukaryotic derivative, possesses antiprotozoal activity.

topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties. Betulinic acid acts as a new activator of NF-kB. Purity: >98.0% Purity: >98% Clinical Data: Phase 2 Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg, 200 mg, 500 mg Size: 1 mg, 5 mg

Betulonic acid Bevirimat (Betunolic acid; Liquidambaric acid; (+)-Betulonic acid) Cat. No.: HY-N1451 (PA-457; MPC-4326; YK FH312) Cat. No.: HY-N0842

Betulonic acid belongs to the pentacyclic Bevirimat (PA-457; MPC-4326; YK FH312) is an triterpenic derivative class, has antitumor anti-HIV drug derived from a betulinic acid-like activities. In vitro: BEA-NP is found over compound; is believed to inhibit HIV by a novel three-times more permeable than that solubilized mechanism, so-called maturation inhibition. by DMSO in Caco-2 cell monocultures.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Phase 2 Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Bilobalide Bisabolangelone ((-)-Bilobalide) Cat. No.: HY-N0076 Cat. No.: HY-N4233

Bilobalide is a biologically active terpenic Bisabolangelone, a sesquiterpene derivative, is trilactone present in Ginkgo biloba. An increasing isolated from the roots of Osterici Radix. number of studies have demonstrated its neuroprotective effects.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

16 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Blinin Bonducellpin D Cat. No.: HY-N0463 Cat. No.: HY-N2949

Blinin is a neoclerodane diterpene, isolated from Bonducellpin D is a furanoditerpenoid lactone the whole plant of Conyza blinii. isolated from Caesalpinia minax. Bonducellpin D exhibits broad-spectrum inhibition potential against SARS-CoV Mpro and MERS-CoV pro M , with an Ki of 467.11 and 284.86 nM, respectively. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg

Brevilin A Britannilactone Cat. No.: HY-N2959 (Desacetylinulicin) Cat. No.: HY-N0895

Brevilin A is a sesquiterpene lactone isolated Britannilactone(Desacetylinulicin) is a methanol from Centipeda minima with anti-tumor activity. extract of the dried flower of Inula britannica L. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 µM) in Cancer Cells. Purity: 99.77% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Britannin Brusatol Cat. No.: HY-N3005 (NSC 172924) Cat. No.: HY-19543

Britannin, isolated from Inula aucheriana, is a Brusatol (NSC 172924), isolated from the Brucea sesquiterpene lactone. Britannin induces apoptosis javanica plant, inhibits Nrf2. and autophagy by activating AMPK regulated by ROS in liver cancer cells. Britannin has anti-proliferative and anti-inflammatory activities. Purity: >98% Purity: 99.89% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Buddlejasaponin IVb Caesalmin B Cat. No.: HY-N2138 Cat. No.: HY-N2981

Buddlejasaponin IVb (Compound 2), a triterpene Caesalmin B is a furanoditerpenoid lactone saponin isolated from Clinopodium chinense isolated from Caesalpinia minax. Caesalmin B (Benth.) O. Kuntze, Compound 2 has hemostasis exhibits antiviral activity. efficacy, shortens thrombin time (TT) by 20.6 %.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Cafestol Calenduloside E Cat. No.: HY-N6257 Cat. No.: HY-N6850

Cafestol, one of the major components of coffee, Calenduloside E (CE) is a natural pentacyclic is a coffee-specific diterpene from. Cafestol is a triterpenoid saponin extracted from Aralia elata. ERK inhibitor for AP-1-targeted activity against Calenduloside E (CE) has anti-apoptotic potent by

PGE2 production and the mRNA expression of targeting heat shock protein 90 (Hsp90). cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Purity: >98% Purity: 98.47% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

www.MedChemExpress.com 17

Camphor Canthaxanthin ((±)-Camphor) Cat. No.: HY-N0808 (E 161g; all-trans-Canthaxanthin) Cat. No.: HY-B1960

Camphor ((±)-Camphor) is a topical anti-infective Canthaxanthin is a red-orange carotenoid with and anti-pruritic and internally as a stimulant various biological activities, such as and carminative. However, Camphor is poisonous antioxidant, antitumor properties. when ingested. Antiviral, antitussive, and anticancer activities. Camphor is a TRPV3 agonist. Purity: >98.0% Purity: >95.0% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 5 mg, 10 mg, 50 mg, 100 mg

Carabrone Carboxyatractyloside Cat. No.: HY-N5020 (Gummiferin) Cat. No.: HY-N1502

Carabrone is isolated from the fruits of Carboxyatractyloside is a toxic natural product, Carpesium abrotanoides , is a well-known acts as an inhibitor of ADP/ATP carrier, inhibits sesquiterpene and exhibits significant mitochondrial ADP/ATP transport. anti-bacterial and anti-tumor activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Carboxyatractyloside dipotassium Carnosic acid (Gummiferin dipotassium) Cat. No.: HY-N2522 Cat. No.: HY-N0644

Carboxyatractyloside dipotassium is a toxic Carnosic acid has demonstrated inhibition of natural product, acts as an inhibitor of ADP/ATP oxidative stress and inflammation, suppression of carrier, inhibits mitochondrial ADP/ATP transport. cell proliferation, and antibacterial activity.

Purity: 98.69% Purity: 99.53% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Carvacrol Carveol Cat. No.: HY-N0711 Cat. No.: HY-W017370

Carvacrol is a monoterpenoid phenol isolated from Carveol is an endogenous metabolite. Lamiaceae family plants, with antioxidant, anti-inflammatory and anticancer properties. Carvacrol causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Purity: 99.99% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 500 mg

Catalpol Caulophyllogenin (Catalpinoside) Cat. No.: HY-N0820 Cat. No.: HY-N7687

Catalpol, an iridoid glycoside, has Caulophyllogenin is a triterpene saponin extracted neuroprotective, anti-inflammatory, and from M. polimorpha. Caulophyllogenin is a anti-hepatitis virus effects. IC50 Value: Target: partial PPARγ agonist, with an

neuroprotective, anti-inflammatory, and EC50of12.6μM. Caulophyllogenin can be used anti-hepatitis virus natural product. for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation. Purity: 98.04% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg Size: 1 mg

18 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Cauloside C Cauloside D Cat. No.: HY-N6919 Cat. No.: HY-N6878

Cauloside C is a triterpene glycoside isolated Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the exerts anti-inflammatory effects through the inhibition of expression of iNOS and inhibition of expression of iNOS and proinflammatory cytokines. proinflammatory cytokines.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Cauloside F Ceanothic acid Cat. No.: HY-N6265 (Emmolic acid) Cat. No.: HY-N3558

Cauloside F is a triterpenoid saponin isolated Ceanothic acid (Emmolic acid) is a ring-A from Clematis akebioides. homologue of betulinic acid. Ceanothic acid inhibits OVCAR-3, HeLa, and FS-5 cells with the cell survival of 68%, 65%, and 81%, respectively.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg

Cedrol Celosin I ((+)-Cedrol; α-Cedrol) Cat. No.: HY-N2071 Cat. No.: HY-N7026

Cedrol is a bioactive sesquiterpene, a potent Celosin I, an oleanane-type triterpenoid saponin competitive inhibitor of cytochrome P-450 isolated from the seeds of Celosia argentea L, could (CYP) enzymes. Cedrol inhibits CYP2B6-mediated be used as chemical markers for the quality bupropion hydroxylase and CYP3A4-mediated control of C. argentea seeds. midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: Size: 10 mM × 1 mL, 100 mg Size: 1 mg, 5 mg

Cephalomannine Chikusetsusaponin Iva Cat. No.: HY-77554 (Calenduloside F) Cat. No.: HY-N0818

Cephalomannine is a Paclitaxel (HY-B0015) Chikusetsusaponin IVa a major active ingredient of alkaloidal analog and isolated from most triterpenoid saponins, exerts antithrombotic Cephalotaxus species. Cephalomannine is an orally effects, including minor hemorrhagic events. This active anti-tumor agent and can be used as a appears to be important for the development of new chemotherapy agent for cancer research. therapeutic agents.

Purity: 98.38% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Chlorahololide C Cimicifugoside Cat. No.: HY-N8404 Cat. No.: HY-N7119

Chlorahololide C, a lindenane sesquiterpenoid Cimicifugoside, a triterpenoid isolated from dimer, is isolated from Chloranthus holostegius. Cimicifuga simplex, is a novel specific Chlorahololide C is a potent and selective nucleoside transport inhibitor that displays potassium channel blocker, with an IC50 of 3.6 μM. synergistic potentiation of methotrexate cytotoxicity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: Size: 1 mg, 5 mg Size: 1 mg, 5 mg

www.MedChemExpress.com 19

Cimigenol Cimigenol-3-O-α-L-arabinoside Cat. No.: HY-N6988 Cat. No.: HY-N2042

Cimigenol is an active compound isolated from Cimigenol-3-O-α-L-arabinoside is a triterpenoid Cimicifuga, with potent anti-tumor activity. isolated from Cimicifuga foetida L.

Purity: 99.79% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Cimigenoside Cimiracemoside C Cat. No.: HY-N2097 (Cimicifugoside M) Cat. No.: HY-N6971

Cimigenoside is an active compound from genus Cimiracemoside C is an active component of Cimicifuga. Cimicifuga racemosa, activates AMPK, has the potential activity against diabetes.

Purity: >98% Purity: 99.55% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Cimiracemoside D cis-Isolimonenol Cat. No.: HY-N0900 ((1S,4R)-p-Mentha-2,8-dien-1-ol) Cat. No.: HY-41094

Cimiracemoside D is a natural product found in cis-Isolimonenol ((1S,4R)-p-Mentha-2,8-dien-1-ol) Actaea racemosa with unknown details. is a chemical composition of essential oil.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 500 mg

cis-p-Menthan-1,8-diol Citral (4-p-Menthan-1,8-diol) Cat. No.: HY-N4324 Cat. No.: HY-N7083

cis-​p-​Menthan-​1,​8-​diol is a natural menthane Citral is a monoterpene found in Cymbopogon monoterpenoid. citratus essential oil, with antihyperalgesic, anti-nociceptive and anti-inflammatory effects.

Purity: >98% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg

Citronellol Ciwujianoside B ((±)-Citronellol; (±)-β-Citronellol) Cat. No.: HY-W010201 Cat. No.: HY-N0307

Citronellol ((±)-Citronellol) is a monoterpene Ciwujianoside B is isolated from Eleutherococcus Pelargonium capitatum. senticosus leaf, is able to penetrate and work in the brain after the oral administration. Ciwujianoside B significantly enhances object recognition memory.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 5 mg, 10 mg

20 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Clinodiside A Columbin Cat. No.: HY-N1371 Cat. No.: HY-N0389

Clinodiside A is isolated from the Chinese Columbin is an orally active diterpenoid medicinal herb Clinopodium chinensis. furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects.

Columbin selectively inhibits COX-2 (EC50=53.1

μM) over COX-1 (EC50=327 μM).

Purity: >98% Purity: 98.86% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

Continentalic acid Coronalolic acid Cat. No.: HY-N6908 (Coronalonic acid) Cat. No.: HY-N3625

Continentalic acid from Aralia continentalis has Coronalolic acid, extract from the apical bud of minimum inhibitory concentrations (MICs) of Gardenia sootepenesis Hutch, inhibits TNF-α-induced approximately 8-16 µg/mL against S. aureus, NF-κB activity and NO production. including the Methicillin susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus… Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Corosolic acid Costunolide (Colosolic acid) Cat. No.: HY-N0280 ((+)-Costunolide; Costus lactone) Cat. No.: HY-N0036

Corosolic acid (Colosolic acid) isolated from the Costunolide ((+)-Costunolide; Costus lactone) is a fruit of Cratoegus pinnatifida var. psilosa, was bioactive sesquiterpene lactone, with reported to have anticancer activity. antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Purity: >98.0% Purity: 99.84% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Crocin II Cucurbitacin B Cat. No.: HY-N0698 Cat. No.: HY-N0416

Crocin II is isolated from the fruit of Gardenia Cucurbitacin B belongs to a class of highly jasminoides with antioxidant, anticancer, and oxidized tetracyclic triterpenoids; could repress antidepressant activity. Crocin II inhibits NO cancer cell progression. production with an IC50 value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2. Purity: >98% Purity: 99.92% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

Cucurbitacin D Cucurbitacin E Cat. No.: HY-N1986 (α-Elaterin; α-Elaterine) Cat. No.: HY-N0417

Cucurbitacin D is an active component in Cucurbita Cucurbitacin E is a natural compound which from texana, disrupts interactions between Hsp90 and the climbing stem of Cucumic melo L. two co-chaperones, Cdc37 and p23. Cucurbitacin D Cucurbitacin E significantly suppresses the prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) activity of the cyclin B1/CDC2 complex. maturation without induction of the heat shock response. Anti-cancer activity. Purity: >98.0% Purity: 99.92% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

www.MedChemExpress.com 21

Cucurbitacin I Cucurbitacin IIa (Elatericin B; JSI-124; NSC-521777) Cat. No.: HY-N1405 (Hemslecin A) Cat. No.: HY-N1988

Cucurbitacin I is a natural selective inhibitor of Cucurbitacin IIa is a triterpene isolated from JAK2/STAT3, with potent anti-cancer activity. Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin, reduces phospho-Histone H3 and increases cleaved PARP in cancer cells.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Cucurbitacin IIb Cucurbitacin S Cat. No.: HY-N1987 Cat. No.: HY-N0725

Cucurbitacin IIb is an active component isolated Cucurbitacin S is isolated from cucurbitaceae with from Hemsleya amabilis, induces apoptosis anticancer and anti-inflammatory activities. with anti-inflammatory activity.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

Curcumol Curdione ((-)-Curcumol) Cat. No.: HY-N0104 ((+)-Curdione) Cat. No.: HY-N0353

Curcumol ((-)-Curcumol), a bioactive Curdione, one of the major sesquiterpene compounds sesquiterpenoid, possesses numerous from Rhizoma Curcumae, has been shown to exhibit pharmacological activities like anticancer, multiple bioactive properties. antimicrobial, antifungal, antiviral, and antiinflammatory.

Purity: 99.58% Purity: 99.44% Clinical Data: Phase 3 Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg

Curzerene Cycloastragenol Cat. No.: HY-N1963 (Cyclogalagenin; Cyclogalegenin; Cyclogalegigenin) Cat. No.: HY-N0424

Curzerene is a sesquiterpene is isolated from the Cycloastragenol, a natural tetracyclic rhizome of Curculigo orchioides Gaertn with triterpenoid, was first identified when screening anti-cancer activity. Curzerene inhibits Astragalus membranaceus extracts for active glutathione S-transferase A1 (GSTA1) mRNA and ingredients with antiaging properties. protein expression. Curzerene induces cell apoptosis. Purity: >97.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Cynaropicrin Cyperotundone Cat. No.: HY-N2350 Cat. No.: HY-N3004

Cynaropicrin is a sesquiterpene lactone which can Cyperotundone is a sesquiterpene isolated from inhibit tumor necrosis factor (TNF-α) release Nagarmotha (Cyperus rotundus).

with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively.

Purity: 97.40% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

22 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Daphylloside Darutigenol Cat. No.: HY-N6245 Cat. No.: HY-N3003

Daphylloside is an iridoid isolated from the Darutigenol is an ent-pimarane-type diterpenoid aerial parts of Galium verum. isolated from Siegesbecikia orientalis L..

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Darutoside Deapi-platycodin D3 Cat. No.: HY-N6028 Cat. No.: HY-N3520

Darutoside is a diterpenoid isolated from Deapi-platycodin D3 is a triterpenoid saponin from Siegesbeckia. the roots of Platycodon grandiflorum.

Purity: >98% Purity: 98.17% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Deapioplatycodin D Dehydroabietic acid Cat. No.: HY-N0588 Cat. No.: HY-N6869

Deapioplatycodin D is a triterpenoid saponin Dehydroabietic acid possesses antiviral activity. isolated from Platycodon grandiflorum, with anti-HCV activity.

Purity: 95.44% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Dehydroandrographolide Dehydroandrographolide succinate Cat. No.: HY-N0676 Cat. No.: HY-N0677

Dehydroandrographolide is extracted from herbal Dehydroandrographolide succinate, extracted from medicine Andrographis paniculata Nees. herbal medicine Andrographis paniculata (Burm f) Dehydroandrographolide reduces oxidative stress in Nees, is widely used for the treatment of viral LPS-induced acute lung injury by inactivating pneumonia and viral upper respiratory tract iNOS. Dehydroandrographolide has anti-infective infections because of its immunostimulatory, activity. anti-infective and anti-inflammatory effect. Purity: 99.93% Purity: 99.88% Clinical Data: Launched Clinical Data: Launched Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

Dehydroandrographolide succinate potassium sodium salt Dehydrocostus Lactone Cat. No.: HY-N0677B ((-)-Dehydrocostus lactone; Epiligulyl oxide) Cat. No.: HY-N0591

Dehydroandrographolide succinate (potassium sodium Dehydrocostus Lactone is a major sesquiterpene salt), extracted from herbal medicine Andrographis lactone isolated from the roots of Saussurea paniculata (Burm f) Nees, is widely used for the lappa. treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective… Purity: >98% Purity: 99.97% Clinical Data: Launched Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

www.MedChemExpress.com 23

Dehydroeburicoic acid monoacetate Dehydroleucodine (3-O-Acetyldehydroeburicoic acid) Cat. No.: HY-N4125 Cat. No.: HY-122295

Dehydroeburicoic acid monoacetate (Compound 18) is Dehydroleucodine is a sesquiterpene lactone a lanostane triterpenoid isolated from isolated from Gynoxys verrucosa. Dehydroleucodine is Wolfiporia cocos. a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 1 mg, 5 mg

Demethylzeylasteral Deoxyandrographolide Cat. No.: HY-N0587 Cat. No.: HY-N0857

Demethylzeylasteral is a triterpene compound Deoxyandrographolide, isolated from the isolated from Tripterygium wilfordii Hook F, Andrographis paniculata, suppresses LPS induced with anti-inflammatory, immunosuppressive and increase in mRNA levels of iNOS as well as anti-tumor activities. Demethylzeylasteral can production of proinflammatory mediators TNF-α and significantly alleviates atherosclerosis (AS). IL-6. Deoxyandrographolide potentiates NGF-induced neurite outgrowth. Purity: 99.90% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Deoxyelephantopin Dihydroartemisinin Cat. No.: HY-N2491 (Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol) Cat. No.: HY-N0176

Deoxyelephantopin, a natural bioactive Dihydroartemisinin is a potent anti-malaria sesquiterpene lactone from Elephantopus scaber, has agent. shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling.

Purity: >98% Purity: 99.03% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 50 mg, 100 mg, 200 mg, 500 mg

Dihydrocephalomannine Dihydrocucurbitacin B Cat. No.: HY-N7256 Cat. No.: HY-N4171

Dihydrocephalomannine (compound 1b), an analogue Dihydrocucurbitacin B, a triterpene isolated from of Paclitaxel, shows reduced cytotoxicity and Cayaponia tayuya roots, inhibits nuclear factor of tubulin binding compared to Paclitaxel. activated T cells (NFAT), induces cell cycle arrested in the G0 phase, and inhibits delayed type hypersensitivity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Diosbulbin B Dipotassium glycyrrhizinate Cat. No.: HY-N0429 Cat. No.: HY-N0184A

Diosbulbin B is a diterpene lactone isolated from Dipotassium glycyrrhizinate is a natural compound, D. bulbifera L., with anti-tumor activity. inhibits atopic dermatitis-related gene expression Diosbulbin B can induce liver injury. with anti-anti-inflammatory activity.

Purity: 99.90% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

24 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Dipsacoside B Docetaxel Cat. No.: HY-N0266 (RP-56976) Cat. No.: HY-B0011

Dipsacoside B is a major bioactive saponin, which Docetaxel (RP-56976) is a can be used as a marker. microtubule depolymerization inhibitor,

with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Purity: >98% Purity: 99.96% Clinical Data: No Development Reported Clinical Data: Launched Size: 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 100 mg, 200 mg

Docetaxel Trihydrate Dodecanoic acid ingenol ester (RP-56976 Trihydrate) Cat. No.: HY-B0011A Cat. No.: HY-N0867

Docetaxel Trihydrate (RP-56976 Trihydrate) is an Dodecanoic acid ingenol ester is a natural antineoplastic agent and inhibits compound. microtubule depolymerization with an IC50 value of 0.2 μM. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the.

Purity: 99.86% Purity: >98.0% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 5 mg

Dulcoside A Echinocystic acid Cat. No.: HY-N6992 Cat. No.: HY-N0271

Dulcoside A is isolated from Stevia rebaudiana, it Echinocystic acid a pentacyclic triterpene often advertised as a sweetener. isolated from the fruits of Gleditsia sinensis Lam, has potent antioxidant, anti-inflammatory and anti-tumor properties. In vitro: Echinocystic acid (EA) inhibit the formation of osteoclast.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Eclalbasaponin I Ecliptasaponin A Cat. No.: HY-N7022 Cat. No.: HY-N1508

Eclalbasaponin I is isolated from Eclipta prostrata Ecliptasaponin A , a pentacyclic triterpenoid L with antitumor activity. Eclalbasaponin I saponin, is one of major compounds separated from inhibits the proliferation of hepatoma cell Eclipta prostrate. smmc-7721 with an IC50 value of 111.1703 μg/ml.

Purity: >98% Purity: 99.05% Clinical Data: Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

Ecliptasaponin D Eleutheroside E Cat. No.: HY-N2191 Cat. No.: HY-N0272

Ecliptasaponin D is a triterpenoid glucoside Eleutheroside E, a principal component of isolated from Eclipta alba (L.) Hassk which is the Eleutherococcus enticosus, has anti-inflammatory aerial part of Eclipta prostrate. and protective effects in ischemia heart.

Purity: >98% Purity: 99.65% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

www.MedChemExpress.com 25

Emodin-8-glucoside Englerin A Cat. No.: HY-N0311 Cat. No.: HY-133168

Emodin-8-glucoside is an anthraquinone derivative Englerin A is a potent and selective activator of

isolated from Aloe vera, binds to minor groove of TRPC4 and TRPC5 channels, with EC50s of 11.2 DNA. and 7.6 nM, respectively. Englerin A can induce renal carcinoma cells death by elevated Ca2+ influx and Ca2+ cell overload.

Purity: 98.32% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Epibetulinic acid Epifriedelanol Cat. No.: HY-N0223 Cat. No.: HY-N1931

Epibetulinic acid, isolated from the root bark of Epifriedelanol is a triterpenoid isolated from the Maytenus cuzcoina and the leaves of Maytenus root bark of Ulmus davidiana, with antitumor chiapensis, exhibits potent inhibitory effects on activity. Epifriedelanol inhibits cellular NO and prostaglandin E2 (PGE2) production in senescence in human primary cells. mouse macrophages (RAW 264.7) stimulated with

bacterial endotoxin with IC50s of 0.7 and 0.6… Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

Ergolide Erythrodiol Cat. No.: HY-N6893 Cat. No.: HY-N2419

Ergolide is a sesquiterpene lactone isolated from Erythrodiol is an olive oil component. Erythrodiol the dried flowers of Inula Britannica. Ergolide promotes Cholesterol efflux (ChE) by selectively inhibits inducible nitric oxide synthase and inhibiting the degradation of ABCA1 protein. cyclo-oxygenase-2 expression in RAW 264.7 Erythrodiol is a good candidate to be further macrophages through the inactivation of NF-κB. explored for therapeutic or preventive application in the context of atherosclerosis. Purity: 99.13% Purity: >98% Clinical Data: Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Escin Escin IB Cat. No.: HY-B2114 Cat. No.: HY-N0555

Escin, a natural mixture of triterpenoid saponins Escin IB is a saponin isolated from skin and the isolated from horse chestnut (Aesculus endosperm of seeds of horse chestnut (Aesculus hippocastanum) seeds, can be used as a hippocastanum). Escin IB shows inhibitory vasoprotective anti-inflammatory, anti-edematous effect on pancreatic lipase activity. and anti-nociceptive agent.

Purity: >95.0% Purity: 98.60% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg Size: 10 mM × 1 mL, 5 mg

Esculentoside A Esculentoside H Cat. No.: HY-N0632 Cat. No.: HY-N2205

Esculentoside A (EsA), a kind of triterpene Esculentoside H (EsH) is a water-soluble saponin saponin isolated from roots of Phytolacca esculenta. isolated and purified from the root extract of Esculentoside A (EsA) possesses anti-inflammatory perennial plant Phytolacca esculenta. activity in acute and chronic experimental models, Esculentoside H (EH) has anti-tumor activity, the has selective inhibitory activity towards mechanism is related to the capacity for cyclooxygenase-2 (COX-2). TNFrelease. Purity: 98.27% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

26 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Esculin Eupalinilide B Cat. No.: HY-N0188 Cat. No.: HY-N6955

Esculin, a fluorescent coumarin glucoside, is an Eupalinilide B is a sesquiterpenoid isolated from active ingredient of ash bark. Esculin ameliorates Genus Eupatorium. cognitive impairment in experimental diabetic nephropathy (DN), and exerts antioxidative stress and antiinflammatory effects, via the MAPK signaling pathway. Purity: 99.97% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg Size: 1 mg, 5 mg

Eupalinolide B Eupalinolide K Cat. No.: HY-N0753 Cat. No.: HY-N2240

Eupalinolide B is a germacrane sesquiterpene Eupalinolide K, a sesquiterpene lactones compound isolated from Eupatorium lindleyanum. from Eupatorium lindleyanum, is a STAT3 Eupalinolide B demonstrates potent cytotoxicity inhibitor. Eupalinolide K is a Michael reaction against A-549, BGC-823 and HL-60 tumour cell acceptor (MRA) . lines.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Euphol Euphorbadienol Cat. No.: HY-N0313 (alpha-Euphorbol) Cat. No.: HY-125648

Euphol is a tetracyclic triterpene alcohol Euphorbadienol (alpha-Euphorbol), a triterpenic isolated from the sap of Euphorbia tirucalli with compound, isolated from the latex of Euphorbia anti-mutagenic, anti-inflammatory and resinifera. The derivatives of Euphorbadienol can immunomodulatory effects, orally active. be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.

Purity: 98.82% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Euphorbia Factor L1 Euphorbia Factor L2 Cat. No.: HY-N2557 Cat. No.: HY-N5001

Euphorbia Factor L1 is a diterpenoid from Euphorbia Euphorbia factor L2, a lathyrane diterpenoid lathyris L., reduces the expression of Bcl-2, PI3K, isolated from caper euphorbia seed (the seeds of AKT and mTOR protein and mRNA, upregulates cleaved Euphorbia lathyris L.), has been traditionally caspase-9 and caspase-3 levels, buts shows no applied to treat cancer. Euphorbia factor L2 shows effect on pro-caspase-9 and pro-caspase-3. potent cytotoxicity and induces apoptosis via a mitochondrial pathway. Purity: >98% Purity: 99.65% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Euphorbiasteroid Eupteleasaponin I Cat. No.: HY-N2032 Cat. No.: HY-N5095

Euphorbiasteroid is a tricyclic diperpene of Eupteleasaponin I is a component of Euptelea Euphorbia lathyris L., inhibits tyrosinase, and polyandra, may has gastroprotective activity. increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

www.MedChemExpress.com 27

Euscaphic acid Farnesol Cat. No.: HY-N2566 Cat. No.: HY-Y0248A

Euscaphic acid, a DNA polymerase inhibitor, is Farnesol is a sesquiterpene alcohol that modulates a triterpene from the root of the R. alceaefolius cell-to-cell communication in Candida albicans, and Poir. Euscaphic inhibits calf DNA polymerase α (pol has the activity in inhibiting bacteria.

α) and rat DNA polymerase β (pol β) with IC50 values of 61 and 108 μM. Euscaphic acid induces apoptosis. Purity: >98% Purity: 99.41% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 500 mg

Farnesyl acetate Fenchyl alcohol Cat. No.: HY-128430 Cat. No.: HY-N7107

Farnesyl acetate is a sesquiterpene isolated from Fenchyl alcohol is a monoterpene alcohol in the the leaves of Amomum gagnepainii. Farnesyl essential oils isolated from Douglas fir needles, acetate has significant toxicity against red palm acts as a fragrance. Fenchyl alcohol strongly

weevil larvae with a LD50 of 7867 ppm. inhibits the rumen microbial activity of both sheep and deer.

Purity: >98% Purity: >98% Clinical Data: Clinical Data: Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Feretoside Ferulenol Cat. No.: HY-N6249 Cat. No.: HY-129605

Feretoside, a phenolic compound extracted from the Ferulenol, a sesquiterpene prenylated coumarin barks of E. ulmoides, is a HSP inducer which act derivative, specifically inhibits succinate as cytoprotective agent. ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Formosanin C Forskolin Cat. No.: HY-N2389 (Coleonol; Colforsin) Cat. No.: HY-15371

Formosanin C is a diosgenin saponin isolated from Forskolin (Coleonol) is a potent adenylate cyclase

Paris formosana Hayata and an immunomodulator with activator with an IC50 of 41 nM and an EC50 of antitumor activity. Formosanin C induces 0.5 μM for type I adenylyl cyclase. Forskolin is apoptosis. also an inducer of intracellular cAMP formation.

Purity: 99.28% Purity: 99.82% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 10 mg, 50 mg, 100 mg, 200 mg

Furanodienone Ganoderenic acid A Cat. No.: HY-N2184 Cat. No.: HY-N2998

Furanodienone is one of the major bioactive Ganoderenic acid A is a lanostane-type triterpene constituents derived from Rhizoma Curcumae. isolated from Ganoderma lucidum. Ganoderenic Furanodienone induced apoptosis. acid A is a potent inhibitor of β-glucuronidase. Ganoderenic acid A has a potent hepatoprotective effect against CCl4-induced liver injury.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

28 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Ganoderenic acid C Ganoderenic acid E Cat. No.: HY-N1515 Cat. No.: HY-N6867

Ganoderenic acid C is a triterpenoid isolated from Ganoderenic acid E is a lanostane-type triterpene Ganoderma lingzhi. Ganoderenic acid C is isolated from Ganoderma lucidum. abundant in fruit bodies at an early growth stage.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ganoderic acid A Ganoderic acid B Cat. No.: HY-N1447 Cat. No.: HY-N2006

Ganoderic acid A can inhibit of the JAK-STAT3 Ganoderic acid B is a triterpene isolated from a signaling pathway, also inhibit proliferation, mushroom Ganoderma lucidum. Ganoderic acid B viability, ROS. inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease. Purity: 99.84% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg Size: 1 mg, 5 mg

Ganoderic acid C2 Ganoderic acid D Cat. No.: HY-N1517 Cat. No.: HY-N1511

Ganoderic acid C2 is a bioactive triterpenoid in Ganoderic acid D, a highly oxygenated tetracyclic Ganoderma lucidum. Ganoderic acid C2 triterpenoid, is the major active component of possesses the potential anti-tumor bioactivity, Ganoderma lucidum. Ganoderic acid D antihistamine, anti-aging and cytotoxic effects. upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Purity: >98% Purity: 99.40% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ganoderic acid G Ganoderic acid H Cat. No.: HY-N2458 Cat. No.: HY-N1513

Ganoderic acid G is a triterpene isolated from the Ganoderic acid H is a lanostane-type triterpene surface part of gills of Ganoderma lucidum. isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling. Purity: >98% Purity: 97.14% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Ganoderic acid TR Ganoderic acid Y Cat. No.: HY-129150 Cat. No.: HY-125713

Ganoderic acid TR is a broad-spectrum inhibitor Ganoderic acid Y is a α-glucosidase inhibitor with against influenza neuraminidases (NAs), an IC50 of 170 μM for yeast α-glucosidase. particularly H5N1 and H1N1 neuraminidases. The Ganoderic acid Y inhibits enterovirus 71 (EV71)

IC50 values of 10.9 and 4.6 μM, respectively. replication through blocking EV71 uncoating.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

www.MedChemExpress.com 29

Ganodermanondiol Ganodermanontriol Cat. No.: HY-N2996 Cat. No.: HY-N1506

Ganodermanondiol is a melanogenesis inhibitor Ganodermanontriol, a sterol isolated from isolated from the Ganoderma Ganoderma lucidum, induces anti-inflammatory lucidum.Ganodermanondiol exhibits potent activity in tert-butyl hydroperoxide cytoprotective effects on tert-butyl (t-BHP)-damaged hepatic cells through the hydroperoxide-induced hepatotoxicity. expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ganolactone B Gardenoin J Cat. No.: HY-N2234 Cat. No.: HY-N3930

Ganolactone B is a lanostane-type triterpene Gardenoin J, a cycloartane triterpene, is isolated isolated from the fruiting bodies of G. sinense. from the exudate of Gardenia thailandica.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Gardenoside Genipin Cat. No.: HY-N1478 ((+)-Genipin) Cat. No.: HY-17389

Gardenoside is a natural compound found in Gardenia Genipin ((+)-Genipin) is a natural crosslinking fruits, with hepatoprotective properties. reagent derived from Gardenia jasminoides Ellis Gardenoside suppresses the pain of chronic fruits. Genipin inhibits UCP2 (uncoupling protein constriction injury by regulating the P2X3 and 2) in cells. P2X7 receptors.

Purity: 99.37% Purity: 99.40% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 50 mg, 100 mg

Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside; Genipin Geniposide 1-β-gentiobioside; Genipin gentiobioside) Cat. No.: HY-N2094 Cat. No.: HY-N0009

Genipin 1-β-D-gentiobioside (Genipin Geniposide is an iridoid glucoside extracted from 1-gentiobioside) is one of the most abundant and Gardenia jasminoides Ellis fruits; exhibits a varity bioactive iridoid glycosides in Gardenia of biological activities such as anti-diabetic, jasminoides Ellis, which possesses antioxidative, antiproliferative and hepatoprotective, anti-inflammatory, antioxidant, neuroprotective activities. and antithrombotic activities. Purity: 99.56% Purity: 99.52% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg Size: 10 mM × 1 mL, 50 mg, 100 mg, 500 mg

Geniposidic acid Gentiopicroside Cat. No.: HY-N0010 (Gentiopicrin) Cat. No.: HY-N0494

Geniposidic acid is an effective anticancer and Gentiopicroside, a naturally occurring iridoid

radioprotection agent. Target: Others Mice were glycoside, inhibits P450 activity, with an IC50

given an intraperitoneal injection of Geniposidic and a Ki of 61 µM and 22.8 µM for CYP2A6; acid (GA) (12.5, 25, 50 mg/kg) 1 h before Gentiopicroside has antianti-inflammatoryand receiving GA against d-galactosamine (GalN) (800 antioxidative effects. mg/kg)/LPS (40 μg/kg). Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 10 mM × 1 mL, 10 mg, 25 mg, 50 mg, 100 mg

30 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Geoside Geraniol (Gein; Eugenyl vicianoside) Cat. No.: HY-N6903 Cat. No.: HY-N6952

Geoside (Gein) is a natural compound isolated from Geraniol, an olefinic terpene, was found to stevia rebaudiana. inhibit growth of Candida albicans and Saccharomyces cerevisiae strains.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg

Gibberellic acid Ginkgolide A (Gibberellin A3) Cat. No.: HY-N1964 (BN-52020) Cat. No.: HY-B0355

Gibberellic Acid is named after a fungus Gibberella Ginkgolide A (BN-52020) is an extract from in fujikuroi . Gibberellic Acid regulates processes of Ginkgo biloba and a g-aminobutyric acid (GABA) plant development and growth, including seed antagonist. development and germination, stem and root growth, cell division, and flowering time.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Ginkgolide B Ginkgolide C (BN-52021) Cat. No.: HY-N0784 (BN-52022; Ginkgolide-C) Cat. No.: HY-N0785

Ginkgolide B (BN-52021), an important active Ginkgolide C is a flavone isolated from Ginkgo terpenoid from Ginkgo biloba leaves, is reported biloba leaves, possessing multiple biological to increase cell viability and decrease cell functions, such as decreasing platelet aggregation apoptosis. and ameliorating Alzheimer disease.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Ginkgolide J Ginkgolide K Cat. No.: HY-N0786 Cat. No.: HY-N4176

Ginkgolide J is a main constituent of the Ginkgolide K, isolated from Ginkgo biloba, induces non-flavone fraction of Ginkgo biloba with an IC50 protective autophagy through the AMPK/mTOR/ULK1 range of 12-54 µM, has neuroprotective and anti signaling pathway. Ginkgolide K possesses neuronal apoptotic ability. neuroprotective activity.

Purity: >98% Purity: 99.83% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg

Ginsenoside C-K Ginsenoside F1 (Ginsenoside compound K; Ginsenoside K) Cat. No.: HY-N0904 (20(S)-Ginsenoside F1) Cat. No.: HY-N0598

Ginsenoside C-K, a bacterial metabolite of G-Rb1, Ginsenoside F1, an enzymatically modified exhibits anti-inflammatory effects by reducing iNOS derivative of Ginsenoside Rg1, demonstrates and COX-2. Ginsenoside C-K exhibits an inhibition competitive inhibition of CYP3A4 activity and against the activity of CYP2C9 and CYP2A6 in weaker inhibition of CYP2D6 activity. human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively. Purity: >98.0% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg

www.MedChemExpress.com 31

Ginsenoside F2 Ginsenoside F3 Cat. No.: HY-125848 Cat. No.: HY-N0600

Ginsenoside F2, a metabolite from Ginsenoside Rb1, Ginsenoside F3, a component of PPTGs (an minor induces apoptosis accompanied by protective saponin in the leaves of Panax ginseng), has autophagy in breast cancer stem cells. immunoenhancing activity by regulating production and gene expression of type 1 cytokines (IL-2, IFN-gamma) and type 2 cytokines (IL-4 and IL-10).

Purity: 99.95% Purity: 99.84% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 1 mg

Ginsenoside F4 Ginsenoside Ra1 Cat. No.: HY-N2503 Cat. No.: HY-N2506

Ginsenoside F4 (GF4), ginseng saponinis, isolated Ginsenoside Ra1 is a component from ginseng, from notoginseng or red ginseng. Ginsenoside F4 inhibits protein tyrosine kinase (PTK) activation (GF4) has inhibitory effect on human lymphocytoma induced by hypoxia/reoxygenation. JK cell by inducing its apoptosis.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ginsenoside Ra2 Ginsenoside Ra3 Cat. No.: HY-N4260 Cat. No.: HY-N4259

Ginsenoside Ra2 is a component from Panax ginseng. Ginsenoside Ra3, isolated from Panax ginseng, possesses anti-cancer activity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ginsenoside Rb1 Ginsenoside Rb2 (Gypenoside III) Cat. No.: HY-N0039 (Ginsenoside C) Cat. No.: HY-N0040

Ginsenoside Rb1, a main constituent of the root of Ginsenoside Rb2 is one of the main bioactive Panax ginseng, inhibits Na+, K+-ATPase components of ginseng extracts. Rb2 can upregulate

activity with an IC50 of 6.3±1.0 μM. Ginsenoside GPR120 gene expression. Ginsenoside Rb2 has also inhibits IRAK-1 activation and phosphorylation antiviral effects. of NF-κB p65 .

Purity: >98.0% Purity: 98.26% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Ginsenoside Rb3 Ginsenoside Rc (Gypenoside IV) Cat. No.: HY-N0041 (Panaxoside Rc) Cat. No.: HY-N0042

Ginsenoside Rb3 is extracted from steamed Panax Ginsenoside Rc, one of major Ginsenosides from

notoginseng. Ginsenoside Rb3 exhibits inhibitory Panax ginseng, enhances GABA receptorA

effect on TNFα-induced NF-κB transcriptional (GABAA)-mediated ion channel currents (IGABA).

activity with an IC50 of 8.2 μM in 293T cell Ginsenoside Rc inhibits the expression of TNF-α lines. Ginsenoside Rb3 also inhibits the induction and IL-1β. of COX-2 and iNOS mRNA. Purity: 99.12% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

32 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Ginsenoside Rd Ginsenoside Rf (Gypenoside VIII) Cat. No.: HY-N0043 (Panaxoside Rf) Cat. No.: HY-N0601

Ginsenoside Rd inhibits TNFα-induced NF-κB Ginsenoside Rf is a trace component of ginseng 2+ transcriptional activity with an IC50 of root. Ginsenoside Rf inhibits N-type Ca 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd channel. inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx.

Purity: >98.0% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Ginsenoside Rg1 Ginsenoside Rg2 (Panaxoside A; Panaxoside Rg1) Cat. No.: HY-N0045 (Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2) Cat. No.: HY-N0602

Ginsenoside Rg1 is one of the major active Ginsenoside Rg2 is one of the major active components of ginseng. Ginsenoside Rg1 displays components of ginseng. Ginsenoside Rg2 acts as a promising effects by reducing cerebral Aβ levels. NF-κB inhibitor. Ginsenoside Rg2 also reduces

Ginsenoside Rg1 also reduces NF-κB nuclear Aβ1-42 accumulation. translocation.

Purity: >98.0% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Ginsenoside Rg5 Ginsenoside Rg6 Cat. No.: HY-N0908 Cat. No.: HY-N0907

Ginsenoside Rg5 is the main component of Red Ginsenoside Rg6 is the component isolated from ginseng. Ginsenoside blocks binding of IGF-1 to its notoginseng. Ginsenoside Rg6 inhibits receptor with an IC50 of ~90 nM. Ginsenoside Rg5 TNF-α-induced NF-κB transcriptional activity with also inhibits the mRNA expression of COX-2 via an IC50 of 29.34±2.22 μM in HepG2 cells. suppression of the DNA binding activities of Ginsenoside Rg6 also exhibits apoptosis-inducing NF-κB p65. effect. Purity: 99.86% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

Ginsenoside Rh1 Ginsenoside Rh2 (Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1) Cat. No.: HY-N0604 (20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2) Cat. No.: HY-N0605

Ginsenoside Rh1 (Prosapogenin A2; Sanchinoside B2; Ginsenoside Rh2 is isolated from the root of Sanchinoside Rh1) is isolated from the root of Ginseng. Ginsenoside Rh2 induces the activation of Panax Ginseng. Ginsenoside Rh1 inhibits the caspase-8 and caspase-9. Ginsenoside Rh2 induces expression of PPAR-γ, TNF-α, IL-6, and IL-1β. cancer cell apoptosis in a multi-path manner.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Ginsenoside Rh3 Ginsenoside Rh7 Cat. No.: HY-N0606 Cat. No.: HY-N4262

Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rh7 is a minor saponin isolated from Ginsenoside Rg5. Ginsenoside Rh3 treatment in the leaves of Panax ginseng. human retinal cells induces Nrf2 activation.

Purity: 99.95% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 1 mg, 5 mg

www.MedChemExpress.com 33

Ginsenoside Rk1 Ginsenoside Rk2 Cat. No.: HY-N2515 Cat. No.: HY-N2504

Ginsenoside Rk1 is a unique component created by Ginsenoside Rk2 is a dammarane glycoside isolated processing the ginseng plant (mainly Sung Ginseng, from the processed ginseng (SG; Sun Ginseng). SG) at high temperatures. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. Purity: 98.53% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Ginsenoside Rk3 Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Cat. No.: HY-N0906 Chikusetsusaponin V) Cat. No.: HY-N0607

Ginsenoside Rk3 is present in the roots Panax Ginsenoside Ro (Polysciasaponin P3; notoginseng herbs. Ginsenoside Rk3 significantly Chikusetsusaponin 5; Chikusetsusaponin V) exhibits inhibits TNF-α-induced NF-κB transcriptional a Ca2+-antagonistic antiplatelet effect with an

activity, with an IC50 of 14.24±1.30 μM in HepG2 IC50 of 155 μM. Ginsenoside Ro reduces the

cells. production of TXA2 more than it reduces the activities of COX-1 and TXAS. Purity: >98% Purity: 99.21% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 25 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Glaucocalyxin A Glycochenodeoxycholic acid sodium salt Cat. No.: HY-N2112 (Chenodeoxycholylglycine sodium salt; …) Cat. No.: HY-N2334A

Glaucocalyxin A, an ent-kauranoid diterpene from Glycochenodeoxycholic acid sodium salt Rabdosia japonica var., induces apoptosis in (Chenodeoxycholylglycine sodium salt) is a bile osteosarcoma by inhibiting nuclear translocation acid formed in the liver from chenodeoxycholate of Five-zinc finger Glis 1 (GLI1) via regulating and glycine. It acts as a detergent to solubilize PI3K/Akt signaling pathway. Glaucocalyxin A has fats for absorption and is itself absorbed. antitumor effect. Purity: 99.38% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 100 mg

Glycyrrhizic acid Gracillin (Glycyrrhizin) Cat. No.: HY-N0184 Cat. No.: HY-N0706

Glycyrrhizic acid is a triterpenoid saponinl, Gracillin is a kind of steroidal saponin isolated acting as a direct HMGB1 antagonist, with from the root bark of wild yam Dioscorea nipponica anti-tumor, anti-diabetic activities. with antitumor agent. Gracillin could induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells.

Purity: >98.0% Purity: >98.0% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 50 mg, 100 mg, 200 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg

Guaiazulene Guggulsterone Cat. No.: HY-N6951 (Z/E-Guggulsterone) Cat. No.: HY-107738

Guaiazulene is present in several essential oils Guggulsterone is a plant sterol derived from the of medicinal and aromatic plants, with antioxidant gum resin of the tree Commiphora wightii. activity. Guaiazulene has in vitro cytotoxic activity against neuron and N2a neuroblastom (N2a-NB) cells.

Purity: >98.0% Purity: 99.50% Clinical Data: Launched Clinical Data: No Development Reported Size: 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

34 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Gymnemagenin Gymnemic acid I Cat. No.: HY-N2268 Cat. No.: HY-N2541

Gymnemagenin is a triterpenoid isolated from G. Gymnemic acid I is a bioactive triterpene saponin sylvestre. Gymnemagenin is an agent for diabetes found in Gymnema sylvestre. Gymnemic acid I and obesity and also possesses antiviral decreases the apoptosis under the high glucose properties. stress.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Gymnestrogenin Gynostemma Extract Cat. No.: HY-N2273 (Ginsenoside C-Mx1; Gynosaponin I; Gypenoside IX) Cat. No.: HY-N0167

Gymnestrogenin is a pentahydroxytriterpene from Gynostemma Extract (Ginsenoside C-Mx1) is a the leaves of Gymnema sylvestre R.Br. natural product.

Gymnestrogenin is a LXR antagonist with IC50s of 2.5 and 1.4 μM for LXRα and LXRβ transactivation, respectively.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

Gypenoside A Gypenoside XLVI Cat. No.: HY-N2440 Cat. No.: HY-N6252

Gypenoside A is a natural compound isolaated from Gypenoside XLVI is one of the major dammarane-type Gynostemma pentaphyllum Makino. triterpenoid saponins from Gynostamma pentaphallum. Gypenoside XLVI has a tetracyclic triterpene structure and possess potent non-small cell lung carcinoma A549 cell inhibitory activity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Gypsogenin-3-O-glucuronide Handelin Cat. No.: HY-N1439 Cat. No.: HY-N2083

Gypsogenin-3-O-glucuronide is a ubiquitous saponin Handelin is a guaianolide dimer from precursor in plants of the genus Gypsophila. Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-κB signaling and pro-inflammatory cytokine production.

Purity: >98% Purity: 99.44% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Harpagide Harpagoside Cat. No.: HY-N0397 Cat. No.: HY-N0396

Harpagide is a class of iridoid glycoside isolated Harpagoside is isolated from Harpagophytum from Scrophularia cryptophila and has antiparasitic procumbens (Hp). Harpagoside has inhibitory effects activity, which exhibits good in vitro on COX-1 and COX-2 activity and inhibits NO trypanocidal activities against African production. trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Purity: >98% Purity: 98.35% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

www.MedChemExpress.com 35

Hastatoside Hederacolchiside A1 Cat. No.: HY-N2015 Cat. No.: HY-N6950

Hastatoside is an iridoid glycoside that is Hederacolchiside A1, isolated from Pulsatilla isolated from Verbena officinalis and has a role in chinensis, suppresses proliferation of tumor cells promoting sleep. by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Hederacoside C Hederacoside D (Kalopanaxsaponin B) Cat. No.: HY-N0253 Cat. No.: HY-N0254

Hederacoside C is a principal active ingredient of Hederacoside D is one of the bioactive saponins Hedera helix leaf that can treat respiratory from Hedera helix, and plays pivotal roles in the disorders, because of its expectorant, overall biological activity. bronchodilator, antibacterial, and bronchospasmolytic effects.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 25 mg, 50 mg Size: 1 mg, 5 mg

Hederagenin Hederagenin 28-O-beta-D-glucopyranosyl ester Cat. No.: HY-N0256 Cat. No.: HY-N2190

Hederagenin is a triterpenoid saponin. It can Hederagenin 28-O-beta-D-glucopyranosyl ester, a inhibit LPS-stimulated expression of iNOS, COX-2, triterpenoid saponin isolated from Ilex cornuta,

and NF-κB. exhibits protective effects against H2O2-induced myocardial cell injury.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

Hederasaponin B Hinokitiol Cat. No.: HY-N0306 (β-Thujaplicin) Cat. No.: HY-B2230

Hederasaponin B, isolated from Hedera helix, has Hinokitiol is a component of essential oils broad-spectrum antiviral activity against various isolated from Chymacyparis obtusa, reduces Nrf2 subgenotypes of Enterovirus 71 (EV71). expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.

Purity: >98% Purity: 99.28% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 50 mg, 100 mg

Hopane-3β,22-diol Hosenkoside C Cat. No.: HY-N4034 Cat. No.: HY-N2251

Hopane-3β,22-diol (compound 74) is a hopane Hosenkoside C is a baccharane glycoside isolated isolated from A. mariesii. from the seeds of Impatiens balsamina.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

36 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Hosenkoside G Icariside B1 Cat. No.: HY-N2242 Cat. No.: HY-N8083

Hosenkoside G, a baccharane glycoside isolated Icariside B1 is a megastigmane glycoside compound from the seeds of Impatiens Balsamina L., isolated from Petasites tricholobus Franch, with an possesses anti-tumor activity. anticancer effect.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ilexhainanoside D Ilexsaponin A Cat. No.: HY-N5040 Cat. No.: HY-N2638

Ilexhainanoside D is the main triterpenoid saponin Ilexsaponin A, isolated from the root of Ilex extracted from Ilex hainanensis Merr., and the pubescens, attenuates ischemia-reperfusion-induced combination of Ilexhainanoside D and ilexsaponin myocardial injury through anti-apoptotic pathway. A1 has anti-inflammation effect.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

Ilexsaponin B2 Incensole Cat. No.: HY-N6256 Cat. No.: HY-N4097

Ilexsaponin B2 is a saponin isolated from the root Incensole, a 14-membered diterpenoid, is isolated of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a from both essential oils and resins of potent phosphodiesterase 5 (PDE5) and PDEI frankincense. Incensole has shown inhibitor with IC50 values of 48.8 μM and 477.5 anti-inflammatory and anti-depression activities μM, respectively. due to their ability to activate ion channels in the brain to alleviate anxiety or depression. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 25 mg, 50 mg

Ingenol Ingenol Mebutate ((-)-Ingenol) Cat. No.: HY-N0865 (Ingenol 3-angelate; PEP005) Cat. No.: HY-B0719

Ingenol is a PKC activator, with a Ki of 30 μM, Ingenol Mebutate is an active ingredient in with antitumor activity. Euphorbia peplus, acts as a potent PKC modulator,

with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity. Purity: >99.0% Purity: 99.07% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg

Ingenol-3,4,5,20-diacetonide Ingenol-5,20-acetonide (Ingenol 3,4:5,20-bisacetonide) Cat. No.: HY-N0871 Cat. No.: HY-N0869

Ingenol-3,4,5,20-diacetonide is a natural Ingenol-5,20-acetonide is an intermediate from compound. ingenol for synthesis of ingenoids; improved stability compared to ingenol.

Purity: 98.60% Purity: 99.73% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg Size: 1 mg

www.MedChemExpress.com 37

Ingenol-5,20-acetonide-3-O-angelate (Ingenol 5,20-acetonide Inulicin 3-angelate; Ingenol 3-angelate 5,20-acetonide) Cat. No.: HY-N0870 (1-O-Acetylbritannilactone) Cat. No.: HY-N0896

Ingenol-5,20-acetonide-3-O-angelate is a natural Inulicin (1-O-Acetylbritannilactone) is an active compound. compound isolated from Inula Britannica L. Inulicin (1-O-Acetylbritannilactone) inhibits VEGF-mediated activation of Src and FAK.

Purity: 98.18% Purity: 99.42% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg

Ipecoside Isoalantolactone Cat. No.: HY-N2261 ((+)-Isoalantolactone; Isohelenin) Cat. No.: HY-N0780

Ipecoside is an alkaloid isolated from Psychotria. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.

Purity: >98% Purity: 99.99% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 10 mg, 50 mg

Isoastragaloside I Isoastragaloside II (Isoastragaloside-I) Cat. No.: HY-N0887 (Astrasieversianin-VII) Cat. No.: HY-N0888

Isoastragaloside I is a natural compound from the Isoastragaloside II is an astragaloside, which is medicinal herb Radix Astragali; possesses the isolated from the hairy root culture of Astragalus activity of elevating adiponectin production. membranaceus.

Purity: 99.43% Purity: 99.38% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg

Isoastragaloside IV Isocolumbin Cat. No.: HY-N4214 Cat. No.: HY-N3050

Isoastragaloside IV is a triterpene oligoglycoside Isocolumbin is a diterpenoid isolated from isolated from Astragali Radix. Jateorhiza palmate Miers (Colombo root).

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Isodeoxyelephantopin Isoescin IA Cat. No.: HY-N2585 Cat. No.: HY-N0556

Isodeoxyelephantopin is a sesquiterpene lactone Isoescin IA is a triterpenoid saponin isolated isolated from Elephantopus scaber. from the seeds of Aesculus chinensis. Isoescin IA Isodeoxyelephantopin induces ROS generation, has anti-HIV-1 protease activity. suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg

38 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Isoescin IB Isoforskolin Cat. No.: HY-N0557 (Coleonol B) Cat. No.: HY-N6927

Isoescin IB, isolated from horse chestnut tree Isoforskolin is the principle active component of seeds, is an isomer of Escin IB. Isoescin IB and C. forskohlii native to China. Isoforskolin reduces Escin IB are the chief active ingredients in the secretion of lipopolysaccharide (LPS)-induced escin. cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 1 mg, 5 mg

Isolimonexic acid Isorosmanol Cat. No.: HY-N8405 Cat. No.: HY-N4191

Isolimonexic acid is a limonoid isolated from Isorosmanol is an abietane-type diterpene isolated lemon (Citrus lemon L. Burm) seed, has from the leaves of sage, with antioxidant, anti-cancer and anti-aromatase (IC50=25.60 neuroprotective and neurotrophic effects. μM) properties. Isorosmanol inhibits AChE activity and melanin synthesis.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Isoscabertopin Isosteviol Cat. No.: HY-N2596 ((-)-Isosteviol; iso-Steviol) Cat. No.: HY-N0872

Isoscabertopin is a sesquiterpene lactone isolated Isosteviol ((-)-Isosteviol) is a derivative of from Elephantopus scaber L and shows anti-tumor Stevioside through acid catalyzed hydrolysis of activities. Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Jolkinolide B Jujuboside B Cat. No.: HY-N0732 Cat. No.: HY-N0660

Jolkinolide B, a bioactive diterpene isolated from Jujuboside B is one of the major bioactive the roots of Euphorbia fischeriana Steud, is known constituents isolated from Zizyphus jujuba. to induce apoptosis in cancer cells. Jujuboside B can inhibit platelet aggregation.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Kaji-ichigoside F1 Kalii Dehydrographolidi Succinas Cat. No.: HY-N2297 (Potassium dehydroandrographolide succinate) Cat. No.: HY-N0677A

Kaji-ichigoside F1 is isolated from S. cuneata with Kalii Dehydrographolidi Succinas (Potassium hemolytic and in vitro antiviral activity. dehydroandrographolide succinate), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its… Purity: >98.0% Purity: 98.70% Clinical Data: No Development Reported Clinical Data: Launched Size: 5 mg Size: 5 mg, 10 mg, 20 mg

www.MedChemExpress.com 39

Kauniolide Kauran-16,17-diol Cat. No.: HY-N0843 (ent-Kauran-16β,17-diol) Cat. No.: HY-N7422

Kauniolide(81066-45-7) is a natural compound. Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and

inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg

Kaurenoic acid Kinsenoside Cat. No.: HY-N1469 Cat. No.: HY-N2292

Kaurenoic acid is a diterpene from Sphagneticola Kinsenoside is a main active component isolated trilobata, inhibits Inflammatory Pain by the from plants of the genus Anoectochilus, and inhibition of cytokine production and activation exhibits many biological activities and of the NO–cyclic GMP–PKG–ATP-sensitive potassium pharmacological effects. channel signaling pathway.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Kongensin A Lasalocid Cat. No.: HY-N3417 (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) Cat. No.: HY-B1071

Kongensin A is a natural product isolated from Lasalocid (Lasalocid-A; Ionophore X-537A; Croton kongensis. Kongensin A is an effective, Antibiotic X-537A) is an antibacterial agent and a covalent HSP90 inhibitor that blocks coccidiostat, used in the feed additives. RIP3-dependent necroptosishas. Kongensin A is a potent necroptosis inhibitor and an apoptosis inducer. Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg

Lasalocid sodium (Lasalocid-A sodium; Ionophore X-537A Lathyrol sodium; Antibiotic X-537A sodium) Cat. No.: HY-B1071A Cat. No.: HY-N0561

Lasalocid sodium (Lasalocid-A sodium) treatment Lathyrol is a natural product, and is used for led to an increase in cell wall thickness, whilst cancer treatment. the quantity and sugar composition of the cell wall remained unchanged in BY-2 cells.

Purity: 97.17% Purity: 98.19% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg

Leelamine hydrochloride Levomenol Cat. No.: HY-110028 ((-)-α-Bisabolol) Cat. No.: HY-N6967

Leelamine hydrochloride is a tricyclic diterpene Levomenol is a monocyclic sesquiterpene alcohol molecule that is extracted from the bark of pine found in various plants and mainly in trees. Matricaria chamomilla, which exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.

Purity: >98% Purity: >98% Clinical Data: Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

40 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Levopimaric acid Licoricesaponin G2 Cat. No.: HY-N7431 Cat. No.: HY-N6983

Levopimaric acid is a type of diterpene resin acid Licoricesaponin G2 is a pentacyclic triterpenoid produced by plants. Levopimaric acid induces isolated from Glycyrrhiza aspera. cancer cell apoptosis and has anticancer, antioxidant, antibacterial and cardiovascular activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Limonin Linalool (Limonoic acid 3,19:16,17 dilactone) Cat. No.: HY-17411 Cat. No.: HY-N0368

Limonin is a triterpenoid enriched in citrus Linalool is natural monoterpene in essential olis fruits, which has antivirus and antitumor ability. of coriander, acts as a competitive antagonist of IC50 Value: Target: HIV; anticancer Limonin is a Nmethyl d-aspartate (NMDA) receptor, with triterpenoid aglycone that is a bitter principle anti-tumor, anti-cardiotoxicity activity. of citrus fruits.

Purity: 99.78% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 50 mg, 100 mg Size: 10 mM × 1 mL, 100 mg

Lindenenol Linderalactone Cat. No.: HY-N2061 Cat. No.: HY-N0781

Lindenenol is isolated from Radix linderae, with Linderalactone is an important sesquiterpene antioxidant and antibacterial activities. lactone isolated from Radix linderae. Linderalactone inhibits cancer growth by modulating the expression of apoptosis-related proteins and inhibition of JAK/STAT signalling pathway.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Linderane Liquidambaric lactone Cat. No.: HY-N0688 Cat. No.: HY-N0497

Linderane, isolated from the root of Lindera Liquidambaric lactone is a compound isolated from strychnifolia, is an irreversible inhibitor Euonymus grandiflorus Wall. cytochrome P450 2C9 (CYP2C9). Linderane has the potential to relieve pain and cramp.

Purity: >95.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Liriope muscari baily saponins C Loganic acid Cat. No.: HY-N0345 Cat. No.: HY-N0513

Liriope muscari baily saponins C is one of major Loganic acid is an iridoid isolated from cornelian active compounds of L. muscari (Decne.) Baily. cherry fruits. Loganic acid can modulate Liriope muscari baily saponins C possesses strong diet-induced atherosclerosis and redox status. anti-inflammatory, immunopharmacological and Loganic acid has strong free radical scavenging cardioprotective activities. activity and remarkable cyto-protective effect against heavy metal mediated toxicity. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 25 mg

www.MedChemExpress.com 41

Loganin Lucidenic acid B (Loganoside) Cat. No.: HY-N0512 Cat. No.: HY-N6861

Loganin, a major iridoid glycoside obtained from Lucidenic acid B is a natural compound isolated Corni fructus, has been shown to have from Ganoderma lucidum, induces apoptosis of anti-inflammatory and anti-shock effects. Loganin cancer cells, and causes the activation of exhibits an anti-inflammatory effect in cases of caspase-9 and caspase-3, and cleavage of PARP. AP and its pulmonary complications through Lucidenic acid B does not affect the cell cycle inhibition of NF-κB activation. profile, or the number of necrotic cells. Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

Lucidenic acid C Lucidenic acid E Cat. No.: HY-N6860 Cat. No.: HY-107265

Lucidenic acid C is a natural compound isolated Lucidenic acid E is a terpenoid from Ganoderma from Ganoderma lucidum, inhibits PMA-induced lucidum. MMP-9 activity, with anti-invasive effect on hepatoma cells.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Lucidenic acid LM1 Lucideric acid A Cat. No.: HY-N6859 Cat. No.: HY-N6862

Lucidenic acid LM1 is a natural triterpenoid Lucideric acid A is a natural compound isolated isolated from Ganoderma lucidum. from Ganoderma lucidum, inhibits PMA-induced MMP-9 activity, with anti-invasive effect on hepatoma cells.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Lup-20(29)-en-28-oic acid Lupenone Cat. No.: HY-N6049 Cat. No.: HY-N2590

Lup-20(29)-en-28-oic acid, a triterpenoid saponins Lupenone, isolated from Rhizoma Musae, of Pulsatilla koreana Root, possesses belongs to lupane type triterpenoids. Lupenone anti-inflammatory and anti-tumor effect. shows various pharmacological activities including anti-inflammatory, anti-virus, anti-diabetes, anti-cancer, improving Chagas disease without major toxicity. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg

Lupeol Macranthoidin A (Clerodol; Monogynol B; Fagarasterol) Cat. No.: HY-N0790 Cat. No.: HY-N2109

Lupeol (Clerodol; Monogynol B; Fagarasterol) is an Macranthoidin A is an orally active saponin from active pentacyclic triterpenoid, has Flos Lonicerae. Macranthoidin A possess protection anti-oxidant, anti-mutagenic, anti-tumor and effects on hepatic injury caused by Acetaminophen, anti-inflammatory activity. Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 25 mg, 50 mg, 100 mg Size: 5 mg, 10 mg, 20 mg

42 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Macranthoidin B Macranthoside B (Macranthoiside I) Cat. No.: HY-N0864 Cat. No.: HY-N5008

Macranthoidin B is a major bioactive saponin in Macranthoside B, isolated from Flos Lonicerae, rat plasma after oral administration of extraction possesses anti-bacterial activity. of saponins from Flos Lonicerae.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

Madecassic acid Madecassoside Cat. No.: HY-N0569 (Asiaticoside A) Cat. No.: HY-N0568

Madecassic acid is isolated from Centella asiatica Madecassoside is a pentacyclic triterpene isolated (Umbelliferae). Madecassic acid has from Centella asitica (L.), as an anti-inflammatory properties caused by iNOS, anti-inflammatory, anti-oxidative activities and COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via anti-aging agent. the downregulation of NF-κB activation in RAW 264.7 macrophage cells. Purity: 98.34% Purity: 99.86% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg, 200 mg

Maoecrystal A Maslinic acid Cat. No.: HY-N2017 (Crategolic acid; 2α-Hydroxyoleanolic acid) Cat. No.: HY-N0629

Maoecrystal A is a compound isolated from leaves Maslinic acid can inhibit the DNA-binding activity of Isodon eriocalyx. of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg

Medicagenic acid Melittoside (Castanogenin) Cat. No.: HY-N2472 Cat. No.: HY-N0915

Medicagenic acid (Castanogenin) is isolated from Melittoside is a natural compound. the roots of Herniaria glabra L, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes.

Purity: >98% Purity: 99.01% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg

Menisdaurin Methyl carnosate Cat. No.: HY-N1927 Cat. No.: HY-136150

Menisdaurin is a cyanogenetic glucoside isolated Methyl camosate is a diterpene isolated from Salvia from Flueggea virosa. officinalis or Rosmarinus officinalis. Methyl camosate has potent antioxidant and anti-bacterial activity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

www.MedChemExpress.com 43

Methyl deacetylasperulosidate (6α-Hydroxygeniposide; Methyl protogracillin Deacetylasperulosidic acid methyl ester) Cat. No.: HY-N1503 (NSC-698793) Cat. No.: HY-N4277

Methyl deacetylasperulosidate is an iridoid Methyl protogracillin (NSC-698793), isolated from isolated from Borreria and Spermacoce species. the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity.

Purity: 99.26% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg Size: 5 mg, 10 mg

Micheliolide Microhelenin C Cat. No.: HY-N0847 Cat. No.: HY-N7595

Micheliolide could effectively attenuate the high Microhelenin C is a sesquiterpene lactone isolated glucose-stimulated activation of NF-κB, the from Helenium microcephalum, with antitumor degradation of IκBα, and the expression of MCP-1, activity. TGF-β1 and FN in rat mesangial cells (MCs).

Purity: 99.59% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg

Mogrol Mogroside I A1 Cat. No.: HY-N2312 Cat. No.: HY-N6854

Mogrol is a biometabolite of mogrosides, and acts Mogroside I A1, a triterpenoid glycoside isolated via inhibition of the ERK1/2 and STAT3 pathways, from the extracts of Luo Han Guo, is a nonsugar or reducing CREB activation and activating sweetener. Mogrosides are sweeter than sucrose. AMPK signaling. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

Purity: 98.06% Purity: 99.77% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg Size: 5 mg, 10 mg

Mogroside I E1 Mogroside II-A2 Cat. No.: HY-N6853 Cat. No.: HY-108272

Mogroside I E1, a triterpenoid glycoside isolated Mogroside II-A2, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and Mogrosides exhibit antioxidant, antidiabetic and anticancer activities. anticancer activities.

Purity: 98.08% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Mogroside II-​A Mogroside IIA1 Cat. No.: HY-N6915 Cat. No.: HY-N6855

Mogroside II-​A is a natural product isolated from Mogroside IIA1, a triterpenoid glycoside isolated Siraitia grosvenorii. from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

Purity: 99.54% Purity: 99.83% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

44 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Mogroside IIe Mogroside III Cat. No.: HY-N6814 Cat. No.: HY-N0500

Mogroside IIe, a triterpenoid glycoside isolated Mogroside III, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and Mogrosides exhibit antioxidant, antidiabetic and anticancer activities. anticancer activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Mogroside III-A1 Mogroside III-E Cat. No.: HY-108271 Cat. No.: HY-N6928

Mogroside III-A1, a triterpenoid glycoside Mogroside III-E is a cucurbitane-type compound isolated from the extracts of Luo Han Guo, is a isolated from Siraitia grosvenorii, inhibits NO nonsugar sweetener. Mogrosides are sweeter than release, with anti-fibrotic activity. sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg

Mogroside IV Mogroside IV-A Cat. No.: HY-N6945 Cat. No.: HY-N6942

Mogroside IV, a triterpenoid glycoside isolated Mogroside IV-A, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and Mogrosides exhibit antioxidant, antidiabetic and anticancer activities. anticancer activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Mogroside IV-E Mogroside V Cat. No.: HY-N2456 Cat. No.: HY-N0502

Mogroside IV-E, a triterpenoid glycoside isolated Mogroside V, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. sweetener. Mogroside V is nearly 300 times sweeter Mogrosides exhibit antioxidant, antidiabetic and than sucrose. Mogrosides exhibit antioxidant, anticancer activities. antidiabetic and anticancer activities. Mogrosides are sweeter than sucrose. Purity: >98% Purity: 98.10% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg

Mogroside VI Mogroside VI A Cat. No.: HY-108275 Cat. No.: HY-N7438

Mogroside VI, a triterpenoid glycoside isolated Mogroside VI A, an isomer of Mogroside VI isolated from the extracts of Luo Han Guo, is a nonsugar from Luo Han Guo, exerts sweetness property. sweetener. Mogrosides are sweeter than sucrose. Mogroside VI A can be used for sweetener and/or Mogrosides exhibit antioxidant, antidiabetic and taste modifier research. anticancer activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

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Mogroside VI B Momordicoside A Cat. No.: HY-N7439 Cat. No.: HY-N2111

Mogroside VI B, a cucurbitane glucoside, separated Momordicoside A is isolated from Momordica from the crude extract of Siraitia grosvenorii. charantia L. Momordicoside A has the inhibitory Mogroside VI B shows effect on activating PGC-1α effect on protein tyrosine phosphatase (PTP1B). transcription.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Momordin Ic Monoammonium glycyrrhizinate hydrate Cat. No.: HY-N0330 Cat. No.: HY-76225

Momordin Ic is a principal saponin constituent of Monoammonium glycyrrhizinate hydrate has various Fructus Kochiae, with with anti-cancer bioactivity. pharmacological actions such as anti-inflammatory, Momordin Ic induces apoptosis through oxidative antiallergic, antigastriculcer, and antihepatitis stress-regulated mitochondrial dysfunction. activities.

Purity: 98.67% Purity: 97.05% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 500 mg, 1 g

Monomelittoside Monotropein (Danmelittoside) Cat. No.: HY-N0916 Cat. No.: HY-N0648

Monomelittoside is a natural compound. Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

Morroniside Mudanpioside C Cat. No.: HY-N0532 Cat. No.: HY-N2163

Morroniside has neuroprotective effect by Mudanpioside C is a monoteepenoid isolated from inhibiting neuron apoptosis and MMP2/9 expression. Paeonia lactiflora Pall .

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg Size: 1 mg, 5 mg

Myricitrin Nagilactone B Cat. No.: HY-N0152 Cat. No.: HY-N3216

Myricitrin, isolated from Daebong persimmon peel, Nagilactone B, extracted from the root bark of is a major antioxidant flavonoid. Podocarpus nagi, is a liver X receptor (LXR) agonist.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg

46 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Neoandrographolide Neocurdione (Neoandrographiside) Cat. No.: HY-N0721 Cat. No.: HY-N4243

Neoandrographolide is a diterpenoid from the Neocurdione is a hepatoprotective sesquiterpene Andrographis paniculata (Acanthaceae). isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice.

Purity: 99.65% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 1 mg, 5 mg

Neoisoliquiritigenin Neotriptophenolide Cat. No.: HY-N2121 Cat. No.: HY-N4082

Neoisoliquiritigenin, isolated from Spatholobus Neotriptophenolide is a sesquiterpene pyridine suberectus, inhibits cell proliferation and induces alkaloid isolated from the root barks of cell apoptosis in breast cancer by directly Tripterygium hypoglaucum. binding to GRP78 to regulate the β-catenin pathway.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Nerolidol Nigranoic acid Cat. No.: HY-N1944 Cat. No.: HY-122935

Nerolidol is a natural membrane-active Nigranoic acid is a triterpenoid separated from sesquiterpene, with antitumor, antibacterial, Schisandra chinensis. Nigranoic acid inhibits HIV-1 antifungal and antiparasitic activity. reverse transcriptase. Nigranoic acid exhibits protective effects on brain through PARP/AIF signaling pathway in cerebral ischemia-reperfusion animal model. Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 5 mg

Nimbin Nimbolide Cat. No.: HY-N3187 Cat. No.: HY-116035

Nimbin is a intermediate limonoid isolated from Nimbolide is a triterpene derived from the leaves Azadirachta. Nimbin prevents tau aggregation and and flowers of neem (Azadirachta indica L). increases cell viability. Nimbin is effective Nimbolide induces apoptosis through inactivation inhibits the envelope protein of dengue virus. of NF-κB. Nimbolide inhibits CDK4/CDK6 kinase activity. Nimbolide suppresses the NF-κB, Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Nomilin Nootkatone Cat. No.: HY-N0547 ((+)-Nootkatone) Cat. No.: HY-N2195

Nomilin is a limonoid compound obtained from the Nootkatone, a neuroprotective agent from Alpiniae extracts of citrus fruits. Nomilin is an Oxyphyllae Fructus, has antioxidant and anti-obesity and anti-hyperglycemic agent . anti-inflammatory effects. Nootkatone improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease.

Purity: 99.35% Purity: 99.35% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 100 mg

www.MedChemExpress.com 47

Notoginsenoside Fa Notoginsenoside Fc Cat. No.: HY-N2530 Cat. No.: HY-N2531

Notoginsenoside Fa, a protopanaxadiol (ppd)-type Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from P. notoginseng, could possibly saponin isolated from the leaves of Panax activate and recover the function of degenerated notoginseng, effectively counteracts platelet brain. aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Notoginsenoside Fe Notoginsenoside FP2 (Notoginseng triterpenes; Ginsenoside Mb) Cat. No.: HY-N0046 Cat. No.: HY-N4305

Notoginsenoside Fe is a natural compound isolated Notoginsenoside FP2, a dammarane-Type Bisdesmoside from Panax japlcus var. isolated from the Fruit Pedicels of Panax notoginseng, has potential to treat cardiovascular disease.

Purity: 99.94% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 5 mg, 10 mg

Notoginsenoside Ft1 Notoginsenoside R1 Cat. No.: HY-N0910 (Sanchinoside R1; Sanqi glucoside R1) Cat. No.: HY-N0615

Notoginsenoside Ft1 is a saponin isolated from Notoginsenoside R1, the main bioactive component Panax notoginseng; stimulator of angiogenesis. in panaxnotoginseng, is reported to have some neuronal protective, antihypertensive effects.

Purity: >98.0% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Notoginsenoside R2 Notoginsenoside S (20(S)-Notoginsenoside R2; Ginsenoside Ng-R2) Cat. No.: HY-N0909 Cat. No.: HY-N5019

Notoginsenoside R2 is a newly isolated Notoginsenoside S is a compound isolated from Panax notoginsenoside from Panax notoginseng, showed notoginseng. neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Nudicaucin A Oleanolic Acid Cat. No.: HY-N5087 (Oleanic acid; Caryophyllin) Cat. No.: HY-N0156

Nudicaucin A is a triterpenoid saponin isolated Oleanolic acid (Caryophyllin) is a natural from Hedyotis nudicaulis. compound from plants with anti-tumor activities.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg, 500 mg

48 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Oleanonic acid Oleonuezhenide (3-Oxooleanolic acid) Cat. No.: HY-N1487 Cat. No.: HY-N3145

Oleanonic acid (3-Oxooleanolic acid) is a Oleonuezhenide, isolated from Fructus Ligustri triterpenoid, inhibits infection by HIV-1 in in Lucidi, exerts neuroprotective effects. vitro infected PBMC, naturally infected PBMC and monocyte/macrophages with EC50 of 22.7 mM, 24.6 mM and 57.4 mM, respectively.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 50 mg Size: 1 mg, 5 mg

Oleuropein Ophiopogonoside A Cat. No.: HY-N0292 Cat. No.: HY-N4274

Oleuropein, found in olive leaves and oil, exerts Ophiopogonoside A is an eudesmane sesquiterpene antioxidant, anti-inflammatory and glycoside isolated from Liriope anti-atherogenic effects through direct inhibition muscari.
. of PPARγ transcriptional activity.

Purity: 98.54% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Orcinol glucoside Oridonin Cat. No.: HY-N0008 (NSC-250682; Isodonol) Cat. No.: HY-N0004

Orcinol glucoside (OG) is an active constituent Oridonin (NSC-250682), a diterpenoid isolated from isolated from Rhizoma Curculiginis, with Rabdosia rubescens, acts as an inhibitor of AKT, antidepressant effects. Orcinol glucoside with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2; facilitates the shift of MSC fate to osteoblast Oridonin possesses anti-tumor, anti-bacterial and and prevents adipogenesis via Wnt/β-catenin anti-inflammatory effects. signaling pathway. Purity: >98% Purity: 99.85% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg

Orientin Oxypaeoniflorin Cat. No.: HY-N0405 Cat. No.: HY-N0748

Orientin is a naturally occurring bioactive Oxypaeoniflorin is a natural product derived from flavonoid that possesses diverse biological Radix Paeoniae Rubra and Radix Paeoniae Alba. properties, including anti-inflammation, anti-oxidative, anti-tumor, and cardio protection. Orientin is a promising neuroprotective agent suitable for therapy for neuropathic pain. Purity: 98.04% Purity: 98.06% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Pachymic acid Paclitaxel (3-O-Acetyltumulosic acid) Cat. No.: HY-N0371 Cat. No.: HY-B0015

Pachymic acid is a lanostrane-type triterpenoid Paclitaxel is a naturally occurring antineoplastic from P. cocos. Pachymic acid inhibits Akt and agent and stabilizes tubulin polymerization. ERK signaling pathways. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.

Purity: >99.0% Purity: 99.97% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 10 mM × 1 mL, 50 mg, 100 mg, 500 mg

www.MedChemExpress.com 49

Paederoside Paederosidic acid Cat. No.: HY-N2432 Cat. No.: HY-N6998

Paederoside is a monoterpene S-methyl Paederosidic acid is isolated from P. scandens thiocarbonate isolated from Paederia with anticancer and antiinflammation activities. pertomentosa. Paederoside shows a high Paederosidic acid inhibits lung caner cells via anti-tumor promoting activity against the inducing mitochondria-mediated apoptosis. Epstein-Barr virus activation.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

Paederosidic acid methyl ester Paeoniflorin Cat. No.: HY-N2433 (Peoniflorin) Cat. No.: HY-N0293

Paederosidic acid methyl ester is a ATPsensitive Paeoniflorin (Peoniflorin), a heat shock K+ channel activator, isolated from protein-inducing compound and a pinane monoterpene P. scandens. glycoside with various bioactivities, such as anticancer effects, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, reducing blood viscosity… Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Phase 3 Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg, 200 mg

Palbinone Palustric acid Cat. No.: HY-N3115 Cat. No.: HY-133593

Palbinone is a terpenoid isolated from the roots Palustric acid is a diterpenic resin acid found in of Paeonia albiflora Pallas, potently inhibits Pinus nigra. 3α-hydroxysteroid dehydrogenase (3α-HSD), with an

IC50 of 46 nM. Anti-inflammatory activity.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Panaxadiol Panaxatriol (20(R)-Panaxadiol) Cat. No.: HY-N0596 Cat. No.: HY-N0597

Panaxadiol is a novel antitumor agent extracted Panaxatriol is a natural product that can relieve from the Chinese medical herb Panax ginseng. myelosuppression induced by radiation injury.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Parishin Parthenolide Cat. No.: HY-N2031 ((-)-Parthenolide) Cat. No.: HY-N0141

Parishin is a phenolic glucoside isolated from Parthenolide is a sesquiterpene lactone found in Gastrodia elata. Parishin exhibits antiaging effects the medicinal herb Feverfew. Parthenolide exhibits and extends the lifespan of yeast via regulation anti-inflammatory activity by inhibiting NF-κB of Sir2/Uth1/TOR signaling pathway. activation; also inhibits HDAC1 protein without affecting other class I/II HDACs.

Purity: 99.10% Purity: 99.88% Clinical Data: No Development Reported Clinical Data: Phase 2 Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 50 mg, 100 mg, 200 mg

50 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Patchouli alcohol Pectolinarin Cat. No.: HY-N0207 Cat. No.: HY-N0314

Patchouli alcohol is a natural tricyclic Pectolinarin, isolated from Cirsium sesquiterpene extracted from Pogostemon cablin chanroenicum, possesses anti-inflammatory (Blanco) Benth, and exhibits anti-Helicobacter activity. Pectolinarin inhibits secretion of IL-6 pylori and anti-inflammatory properties. and IL-8, as well as the production of PGE2 and NO.

Purity: >98.0% Purity: 99.89% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

Pedunculoside Perillyl alcohol Cat. No.: HY-N0458 Cat. No.: HY-N7000

Pedunculoside is a main bioactive component Perillyl alcohol is a monoterpene isolated isolated from Jiubiying. Pedunculoside exerts from the essential oils of lavendin, peppermint, lipid-lowering effects partly through the spearmint, cherries, celery seeds, and several regulation of lipogenesis and fatty other plants. Perillyl alcohol is active in acid β-oxidation. inducing apoptosis in tumor cells without affecting normal cells. Purity: >98% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: Phase 2 Size: 5 mg, 10 mg, 20 mg Size: 100 mg

Phillyrin Phorbol Cat. No.: HY-N0482 (4β-Phorbol) Cat. No.: HY-N2147

Phillyrin is isolated from Forsythia suspensa Vahl Phorbol is a highly toxic diterpene, whose esters (Oleaceae), has antibacterial and have important biological properties. anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities. Purity: 98.99% Purity: 99.32% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg, 50 mg

Phytol Phytolaccagenin ((E)​-​Phytol) Cat. No.: HY-N3075 Cat. No.: HY-N1433

Phytol ((E)​-​Phytol), a diterpene alcohol from Phytolaccagenin, a triterpenoid saponin, is the chlorophyll widely used as a food additive and in active component of Radix Phytolaccae. medicinal fields, possesses promising Phytolcaccagenin has antifungal activity, antischistosomal properties. anti-inflammatory activity and lower toxicity.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 5 mg, 10 mg, 20 mg

Picfeltarraenin IA Picfeltarraenin IB Cat. No.: HY-N1474 Cat. No.: HY-N2211

Picfeltarraenin IA, a triterpenoid obtained from Picfeltarraenin IB, a triterpenoid obtained from Picriafel-terrae Lour (P.fel-terrae), is an Picriafel-terrae Lour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IA can be used for the treatment Picfeltarraenin IB can be used for the treatment of herpes infections, cancer and inflammation. of herpes infections, cancer and inflammation.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

www.MedChemExpress.com 51

Picfeltarraenin IV Picroside I Cat. No.: HY-N5076 (6'-Cinnamoylcatalpol) Cat. No.: HY-N0407

Picfeltarraenin IV, a triterpenoid obtained from Picroside I is the major ingredient of Picrorhiza Picriafel-terrae Lour (P.fel-terrae), is an kurroa. Picrorhiza kurroa is a high value medicinal acetylcholinesterase (AChE) inhibitor. herb due to rich source of hepatoprotective Picfeltarraenin IV can be used for the treatment metabolites, Picroside-I and Picroside-II. of herpes infections, cancer and inflammation. Picroside I is a promising agent for the management of asthma. Purity: >98% Purity: 96.14% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

Picroside II Picroside III Cat. No.: HY-N0408 Cat. No.: HY-N0409

Picroside II, an iridoid compound extracted from Picroside III is an iridoid glycoside isolated Picrorhiza, exhibits anti-inflammatory and from Picrorhiza scrophulariiflora (PS), a anti-apoptotic activities. picroside II alleviates traditional Chinese medicine. the inflammatory response in sepsis and enhances immune function by inhibiting the activation of NLRP3 inflammasome and NF-κB pathways. Purity: 99.77% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 5 mg, 10 mg

Plantamajoside Platicodigenin Cat. No.: HY-N0031 Cat. No.: HY-N1991

Plantamajoside is a phenylpropanoid glycoside Platicodigenin isolated from platycodon isolated from Plantago asiatica L.(Plantaginaceae). grandiflorum. Plantamajoside has protective effects on LPS-induced acute lung injury (ALI) mice model. Plantamajoside has the potential for the treatment of pulmonary inflammation. Purity: 95.42% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Platycodin D Platycodin D2 Cat. No.: HY-N1411 Cat. No.: HY-N4087

Platycodin D is a saponin isolated from Platycodi Platycodin D2 is a saponin isolated from Platycodon Radix, acts as an activator of AMPKα, with grandiflorum, with anti-cancer activity. anti-obesity property.

Purity: 98.03% Purity: 99.36% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Platycodin D3 Platycoside E Cat. No.: HY-N3519 Cat. No.: HY-N3522

Platycodin D3 is a triterpenoid saponin isolated Platycoside E is a platycodigenin-type from Platycodon grandiflorum, with anti-HCV saponin isolated from the root of Platycodon activity. grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

52 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Platycoside G1 Pleuromutilin (Deapi-platycoside E) Cat. No.: HY-N3521 (Drosophilin B; Mutilin 14-glycolate) Cat. No.: HY-N2301

Platycoside G1, a natural product found in Pleuromutilin (Drosophilin B) inhibits bacterial Platycodon grandiflorum, is a triterpenoid protein synthesis by binding to the 50S ribosomal saponin. Platycoside G1 has potent antioxidant subunit of bacteria. activities.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg, 500 mg

Podocarpic acid Polygalacin D Cat. No.: HY-N2318 Cat. No.: HY-N6064

Podocarpic acid is a natural product, which has Polygalacin D (PGD) is a bioactive compound the best all-round positive effect and acts as a isolated from Platycodon grandiflorum (Jacq.) novel TRPA1 activator. with anticancer and anti-proliferative properties.

Purity: 99.56% Purity: 99.30% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 50 mg Size: 1 mg, 5 mg

Polygalasaponin V Polygalaxanthone III Cat. No.: HY-N2169 Cat. No.: HY-N1407

Polygalasaponin V is a triterpenoid saponin Polygalaxanthone III is extracted from polygala isolated from the aerial parts of Polygala japonica. tenuifolia wild, has inhibitory effect towards Polygala japonica has been a folk medicine herb used CYP450 enzyme. Polygalaxanthone III inhibits as expectorant, anti-inflammatory, antibacterial chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 and antidepressant agents in the south of China. with an IC50 of 50.56 μM.

Purity: >98% Purity: 99.76% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

Polyphyllin II Polyporenic acid C Cat. No.: HY-N0048 Cat. No.: HY-N2993

Polyphyllin II is one of the most significant Polyporenic acid C is a lanostane-type saponins in Rhizoma Paridis and has toxic effects triterpenoid isolated from P. cocos. Polyporenic on kinds of cancer cells. Polyphyllin II induces acid C induces cell apoptosis through the death apoptosis through caspases activation and receptor-mediated apoptotic pathway without the cell-cycle arrest. involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy. Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Ponicidin Pristimerin (Rubescensine B) Cat. No.: HY-N1535 (Celastrol methyl ester) Cat. No.: HY-N1937

Ponicidin (Rubescensine B) is a diterpenoid Pristimerin is a potent and reversible derived from Rabdosia rubescens, and exhibits monoacylglycerol lipase (MGL) inhibitor with an immunoregulatory, anti-inflammatory, anti-viral IC50 of 93 nM. and anti-cancer activity.

Purity: 99.79% Purity: 99.64% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

www.MedChemExpress.com 53

Pseudoginsenoside F11 Pseudoginsenoside RT1 (Ginsenoside A1) Cat. No.: HY-N0541 Cat. No.: HY-N2201

Pseudoginsenoside F11 (Ginsenoside A1), a Pseudoginsenoside RT1, isolated from the fruit of component of Panax quinquefolium (American Randia siamensis, exhibits acute ichthyotoxic ginseng), has been demonstrated to antagonize the activity. learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 5 mg, 10 mg

Pseudoginsenoside RT5 Pseudolaric Acid A Cat. No.: HY-N0542 Cat. No.: HY-N0673

Pseudoginsenoside RT5 is isolated from Panax Pseudolaric Acid A is a diterpene acid isolated quinquefolium. from Pseudolarix kaempferi, has antifungal, cytotoxic and antifertile activities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Pseudolaric Acid B Pseudolaric acid B β-D-glucoside Cat. No.: HY-N6939 Cat. No.: HY-N6938

Pseudolaric Acid B is a diterpene isolated from Pseudolaric acid B β-D-glucoside is a diterpenoid the root of Pseudolarix kaempferi Gorden isolated from Pseudolarix kaempferi. (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes.

Purity: 99.47% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 5 mg, 10 mg, 20 mg

Pseudolaric Acid C Pseudolaric Acid C2 Cat. No.: HY-N0672 Cat. No.: HY-N6910

Pseudolaric C is a diterpenoid isolated from the Pseudolaric Acid C2, a diterpenoid isolated from root bark of Pseudolarix kaempferi Gorden, has Pseudolarix kaempferi, is identified as the antifungal activity. specific metabolite of Pseudolaric acid B in plasma, urine, bile and feces after both oral and intravenous administration to rats.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Pulchinenoside A Pulchinenoside C (Anemoside A3) Cat. No.: HY-N0204 (Anemoside B4) Cat. No.: HY-N0205

Pulchinenoside A is a natural triterpenoid saponin Pulchinenoside C (Anemoside B4) is Pulsatilla that enhances synaptic plasticity in the adult koreana Nakai that have many numerous biological mouse hippocampus and facilitates spatial memory effects in vitro, including enhancing in adult mice. hypoglycemic, anti-tumor, neuroprotective and anti-angiogenic activity.

Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

54 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Pulsatilla saponin D Punicalagin (SB365; Hederacolchiside A) Cat. No.: HY-N0834 Cat. No.: HY-N0063

Pulsatilla saponin D (SB365), isolated from the Punicalagin is a polyphenol ingredient isolated root of Pulsatilla koreana Nakai, is an anti-tumor from Pomegranate (Punica granatum L.) or the agent. leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects. Purity: 98.47% Purity: 99.80% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg Size: 5 mg, 10 mg, 20 mg

Quassin Quillaic acid (Nigakilactone D) Cat. No.: HY-N1581 (Quillaja sapogenin) Cat. No.: HY-N0839

Quassin (Nigakilactone D) is a bioactive Quillaic acid(Quillaja sapogenin) is the major triterpenoid from stem bark extract of Quassia aglycone of the widely studied saponins of the amara. Quassin inhibits P. falciparum with an Chilean indigenous tree Quillaja saponaria Mol;

IC50 of 0.15 μM. Quassin possesses reversible can elicit dose-dependent antinociceptive effects antifertility, anti-estrogenic and anti-plasmodial in two murine thermal models. activity. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg

Raddeanin A Rebaudioside A Cat. No.: HY-N0819 Cat. No.: HY-N0466

Raddeanin A is a natural triterpenoid saponin Rebaudioside A is a steviol glycoside, component of Anemone raddeana, with anti-cancer α-glucosidase inhibitor with IC50 of 35.01 activities. Raddeanin A exerts anticancer effect μg/ml.can inhibit ATP-sensitive K+-channels. on human osteosarcoma via the ROS/JNK and NF-κB signal pathway.

Purity: 98.04% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Phase 1 Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 100 mg, 500 mg

Rebaudioside C Rebaudioside D (Dulcoside B) Cat. No.: HY-N0467 Cat. No.: HY-N0468

Rebaudioside C(Dulcoside B) is used as natural Rebaudioside D is a glycoside found in the leaves sweeteners to diabetics and others on of Stevia rebaudiana and acts as a sweetener. carbohydrate-controlled diets.

Purity: 96.39% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 5 mg, 10 mg, 20 mg

Rehmannioside C Rehmannioside D Cat. No.: HY-N2400 Cat. No.: HY-N0912

Rehmannioside C is an iridoid glucoside isolated Rehmannioside D is a carotenoid glycoside. from Radix Rehmanniae Praeparata.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

www.MedChemExpress.com 55

Rehmapicroside Retinyl acetate Cat. No.: HY-N2398 (Retinol acetate; Vitamin A acetate) Cat. No.: HY-N0679

Rehmapicroside is an ionone glycoside isolated Retinyl acetate is a synthetic acetate ester form from rhizomes of Rehmannia glutinosa. derived from retinol and has potential antineoplastic and chemo preventive activities.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg, 500 mg

Rhodojaponin II Rhodojaponin III Cat. No.: HY-N2151 Cat. No.: HY-N2152

Rhodojaponin II is a diterpenoid from the leaves Rhodojaponin III is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory of Rhododendron molle with anti-inflammatory activity. activity.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Rhodojaponin V Roburic acid Cat. No.: HY-N2154 Cat. No.: HY-N0481

Rhodojaponin V is a diterpenoid from the leaves of Roburic acid, a tetracyclic triterpenoid found in Rhododendron molle with anti-inflammatory Gentiana macrophylla, acts as an inhibitor of

activity. COX, with IC50s of 5 and 9 μM for COX-1 and COX-2, respectively.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

Rosamultin Rosarin Cat. No.: HY-N2565 Cat. No.: HY-N0506

Rosamultin is a 19 α-hydroxyursane-type Rosarin is a cinnamyl alcohol glycoside triterpenoid isolated from Potentilla isolated from Rhodiola rosea. Rosarin has anserina L. Rosamultin has inhibitory effects anti-inflammatory and neuroprotective effects. against HIV-1 protease.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Rosavin Rosin Cat. No.: HY-N0507 Cat. No.: HY-N0508

Rosavin is isolated from R. rosea, Rosavin shows Rosin is isolated from pine wood or pine stumps, antidepressant-like, adaptogenic, anxiolytic-like Rosin is a frequent contact allergen which induces effects in mice model. allergic contact dermatitis.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

56 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Rosiridin Rosmarinic acid Cat. No.: HY-N0505 (Labiatenic acid) Cat. No.: HY-N0529

Rosiridin, which is isolated from Rhodiola rosea L., Rosmarinic acid is a widespread phenolic ester inhibits MAO A and MAO B with potential compound in the plants. Rosmarinic acid inhibits beneficial effect in depression and senile MAO-A, MAO-B and COMT enzymes with IC50s dementia. Rosiridin shows an inhibition of 83.8% of 50.1, 184.6 and 26.7 μM, respectively. against MAO B at 10 μM (pIC50=5.38).

Purity: >98% Purity: 99.29% Clinical Data: No Development Reported Clinical Data: Phase 4 Size: 1 mg, 5 mg, 10 mg Size: 10 mM × 1 mL, 50 mg, 100 mg

Rotundic acid Rotundifuran Cat. No.: HY-N2217 Cat. No.: HY-116894

Rotundic acid, a triterpenoid obtained from I. Rotundifuran, a labdane type diterpene, is rotunda, induces DNA damage and cell apoptosis in isolated from Vitex rotundifolia. Rotundifuran can hepatocellular carcinoma through AKT/mTOR and inhibit the cell cycle progression and induce MAPK Pathways. Rotundic acid possesses apoptosis in human myeloid leukaemia cells. anti-inflammatory and cardio-protective abilities.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg

Rubusoside Rupestonic acid Cat. No.: HY-N0668 Cat. No.: HY-N3016

Rubusoside is a natural sweetener and a Rupestonic acid, a sesquiterpene from Artemisia solubilizing agent with antiangiogenic and rupestris L., can inhibit influenza virus. antiallergic properties. Rubusoside is an excellent solubilizing agent.

Purity: 98.58% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

Ruscogenin Rutaevin Cat. No.: HY-N0496 Cat. No.: HY-N2620

Ruscogenin, an important steroid sapogenin derived Rutaevin is isolated from the fruits of Euodia from Ophiopogon japonicus, attenuates cerebral rutaecarpa. Rutaevin inhibits NO production in ischemia-induced blood-brain barrier dysfunction LPS-induced RAW 264.7 macrophages. by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities. Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg Size: 5 mg, 10 mg

Ryanodine Saikogenin A Cat. No.: HY-103306 Cat. No.: HY-N6584

Ryanodine is a cell permeant ryanodine receptor Saikogenin A, extracted from a Chinese herbal modulator. Ryanodine can either stimulate or plant called Tsai-Fu, is a dipeptidyl peptidase-IV inhibit Ryanodine-mediated Ca2+ release depending (DPP-IV) inhibitor. on its concentrations. Poisonous diterpenoid found in Ryania speciosa.

Purity: >98.0% Purity: 98.31% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg Size: 5 mg

www.MedChemExpress.com 57

Saikosaponin A Saikosaponin B1 Cat. No.: HY-N0246 Cat. No.: HY-N0247

Saikosaponin A is an active component of Saikosaponin B1 is a component of Saiko, enhances Bupleurum falcatum, up-regulates LXRα the effect of cancer chemotherapy. expression, with potent anti-inflammatory activity.

Purity: 99.43% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg Size: 5 mg, 10 mg, 20 mg

Saikosaponin B2 Saikosaponin B3 Cat. No.: HY-N0248 Cat. No.: HY-N4219

Saikosaponin B2 is an active component from Saikosaponin B3 is a saikosaponin isolated from Bupleurum kaoi root, acts as an entry inhibitor the roots of Bupleurum falcatum L., with against HCV infection. Anti-cancer activity. analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 1 mg, 5 mg

Saikosaponin B4 Saikosaponin C Cat. No.: HY-N4218 Cat. No.: HY-N0249

Saikosaponin B4 is a member of saikosaponins Saikosaponin C is a bioactive component found in isolated from the roots of B. falcatum, radix bupleuri, targets amyloid beta and tau in selectively inhibits ACTH-induced lipolysis. Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Saikosaponin D Saikosaponin E Cat. No.: HY-N0250 Cat. No.: HY-N4211

Saikosaponin D is a triterpene saponin isolated Saikosaponin E is a saikosaponin isolated from from Bupleurum, with anti-inflammatory, Bupleurum yinchowense. anti-bacterial, anti-tumor, and anti-allergic activities; Saikosaponin D inhibits selectin, STAT3 and NF-kB and activates estrogen receptor-β. Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg Size: 5 mg, 10 mg

Saikosaponin F Saikosaponin G Cat. No.: HY-N2178 Cat. No.: HY-N4216

Saikosaponin F is a component found in Saikosaponin G is a triterpene glycoside isolated Bupleurum (B.) falcatum L. from Bupleuri Radix.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg

58 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Saikosaponin H Salannin Cat. No.: HY-N2603 Cat. No.: HY-123026

Saikosaponin H is a saikosaponin derived from the Salannin, a limonoid bitter principle of the seed herb Radix bupleuri. oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Sandaracopimaric acid Santonin Cat. No.: HY-133594 (Alpha-Santonin) Cat. No.: HY-B1761

Sandaracopimaric acid is a diterpenoid with Santonin is an active principle of the plant anti-inflammatory effect. Sandaracopimaric acid Artemisia cina, which is formely used to treat reduces the contraction of phenylephrine-induced worms. pulmonary arteries with an EC50 of 43.93 μM.

Purity: >98% Purity: 99.80% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 500 mg

Scabertopin Sclareol glycol Cat. No.: HY-N1247 Cat. No.: HY-N7007

Scabertopin, isolated from the whole plant of Sclareol glycol is the precursor of ambroxide. Elephantopus scaber, is a sesquiterpene lactone. Hyphozyma roseonigra ATCC 20624 was the only Scabertopin has been found to be prominent reported strain capable of degrading sclareol to anticancer constituents. the main product of sclareol glycol.

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 1 mg, 5 mg

Scopolin Secaubryenol Cat. No.: HY-N0341 Cat. No.: HY-N1272

Scopolin is a coumarin isolated from Arabidopsis Secaubryenol is a class of 3,4-secocycloartane thaliana (Arabidopsis) roots. Scopolin attenuated triterpenes isolated from Coussarea macrophylla. hepatic steatosis through activation of Secaubryenol does not display any cytotoxic effect SIRT1-mediated signaling cascades. at a dose of 10 µg/mL..

Purity: >99.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg Size: 1 mg, 5 mg

Secologanoside Sesamoside Cat. No.: HY-N6876 Cat. No.: HY-N0412

Secologanoside is a triterpenoid isolated from Sesamoside is a iridoid isolated from the aerial Poraqueiba sericea, weakly inhibits elastase with an part of Phlomis linearifolia. Sesamoside

IC50 of 164 μg/mL. Secologanoside is moderate has antiodant and antiglycation activities. cytotoxic to fibroblasts.

Purity: >98% Purity: 98.74% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

www.MedChemExpress.com 59

Shanzhiside methyl ester Shionone Cat. No.: HY-N0630 Cat. No.: HY-N0829

Shanzhiside methy lester is isolated from L. rotata. Shionone is the major triterpenoid isolated from Shanzhiside methyl ester is a small molecule Aster tataricus, has anti-tussive, anti-inflammatory glucagon-like peptide-1 (GLP-1) receptor agonist activities. Shionone possesses a unique and has the ability to induce anti-allodynic six-membered tetracyclic skeleton and tolerance. 3-oxo-4-monomethyl structure.

Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

Siamenoside I Simvastatin Cat. No.: HY-N0612 (MK 733) Cat. No.: HY-17502

Siamenoside I is one of the mogrosides that has Simvastatin (MK 733) is a competitive inhibitor of

several kinds of bioactivities. HMG-CoA reductase with a Ki of 0.2 nM.

Purity: >98% Purity: 99.81% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 50 mg, 100 mg, 200 mg, 500 mg

Sinigrin Siraitic Acid A Cat. No.: HY-N0404 Cat. No.: HY-N6917

Sinigrin is a major glucosinolate present in Siraitic Acid A is a cucurbitane triterpenoid plants of the Brassicaceae family, with isolated from the root of S. grosvenori . anti-adipogenic effects.

Purity: 99.74% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 25 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

Siraitic Acid B Sodium aescinate Cat. No.: HY-N6916 Cat. No.: HY-N1404

Siraitic Acid B is a cucurbitane triterpenoid Sodium aescinate is a triterpene saponin derived isolated from the root of S. grosvenori . from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Soyasapogenol A Soyasapogenol B Cat. No.: HY-N6073 Cat. No.: HY-N6074

Soyasapogenol A, a triterpene compound, isolated Soyasapogenol B, an ingredient of soybean, exerts from the roots of Abrus cantoniensis. anti-proliferative, anti-metastatic activities. Soyasapogenol B triggers endoplasmic reticulum stress, which mediates apoptosis and autophagy in colorectal cancer.

Purity: 99.06% Purity: 98.26% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg Size: 1 mg, 5 mg, 10 mg

60 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Soyasaponin Ac Soyasaponin II Cat. No.: HY-N6999 Cat. No.: HY-122920

Soyasaponin Ac is a triterpenoid isolated from the Soyasaponin II is a saponin with antiviral seeds of Glycine max. activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg

Soyasaponin III Spathulenol Cat. No.: HY-N7273 Cat. No.: HY-N1205

Soyasaponin III, a monodesmodic oleanane Spathulenol is isolated from Psidium guineense triterpenoid, is one of the main potentially Sw, and has antioxidant, anti-inflammatory, bioactive saponins found in soy (Glycine max) antiproliferative and antimycobacterial and related products. Soyasaponin III can induce activities. Spathulenol shows a high antioxidant apoptosis in Hep-G2 cells. activity with an IC50 of 85.60 μg/mL in the DPPH system.. Purity: >95.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg Size: 1 mg, 5 mg

Specnuezhenide Squalene ((8E)-Nuezhenide) Cat. No.: HY-N0665 (Super Squalene; trans-Squalene; AddaVax) Cat. No.: HY-N1214

Specnuezhenide ((8E)-Nuezhenide) is isolated from Squalene is an intermediate product in the the fruits of Ligustrum lucidum. synthesis of cholesterol, and shows several Specnuezhenide ((8E)-Nuezhenide) can inhibit pharmacological properties such as hypolipidemic, IL-1β-induced inflammation in chondrocytes via hepatoprotective, cardioprotective, antioxidant, inhibition of NF-κB and wnt/β-catenin and antitoxicant activity. signaling. Purity: 98.55% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 5 mg, 10 mg, 25 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Stearyl glycyrrhetinate Steviol Cat. No.: HY-N2417 Cat. No.: HY-N2057

Stearyl glycyrrhetinate, a major component in Steviol is a major metabolite of the sweetening licorice extract, has a MIC against S. aureus compound stevioside. Steviol slows renal cyst strains of more than 256 mg/L. Stearyl growth by reducing AQP2 expression and promoting glycyrrhetinate has antibacterial effects. AQP2 degradation.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 500 mg Size: 5 mg, 10 mg, 20 mg

Steviol-​19-​O-​glucoside Steviolbioside Cat. No.: HY-N6918 Cat. No.: HY-N2547

Steviol-​19-​O-​glucoside is a metabolite of Steviolbioside is a rare sweetener that exists in steviol in the steviol glycosides biosynthesis stevia rebaudiana leaves. Steviolbioside presents pathway in Stevia rebuadiana. inhibition on several human cancer cells and acts as potential remedy for human breast cancer.

Purity: >98% Purity: 98.19% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

www.MedChemExpress.com 61

Stevioside Suavissimoside R1 Cat. No.: HY-N0669 Cat. No.: HY-N7025

Stevioside is a natural sweetener extracted from Suavissimoside R1, isolated from the roots of leaves of Stevia rebaudiana, with anticancer Rubus parvifollus, possesses potent activity. neuroprotective activity and has the potential to treat anti-Parkinson's disease drug.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg

Sweroside Swertiamarin Cat. No.: HY-N0806 Cat. No.: HY-N0807

Sweroside, isolated from Lonicera japonica, Swertiamarin, a secoiridoid glycoside found in exhibits cytoprotective, anti-osteoporotic, and genera of Enicostemma Species, confers hepatoprotective effect. anti-hyperglycemic and anti-hyperlipidemic effects.

Purity: 99.84% Purity: 98.43% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg

Taraxasterol Taraxasteryl acetate Cat. No.: HY-N1178 Cat. No.: HY-N2478

Taraxasterol is a pentacyclic triterpenoid Taraxasteryl acetate is isolated from P. isolated from Taraxacum officinale. Taraxasterol sagittalis,and has a broad spectrum of has a role as a metabolite and an anti-inflammatory activity. Taraxasteryl anti-inflammatory agent. acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema.

Purity: 99.33% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

Taraxerol Taraxerol acetate Cat. No.: HY-N2477 Cat. No.: HY-N2599

Taraxerol is isolated from Abroma augusta L, and Taraxerol acetate is a COX-1 and COX-2 inhibitor

has anti-inflammtory and anti-cancer effects. with IC50 values of 116.3 μM and 94.7 μM, Taraxerol attenuates acute inlammation through respectively. Taraxerol acetate the has the inhibition of NF-κB signaling pathway. Taraxerol anticancer potential and induces cell induces cell apoptosis. apoptosis.
.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg, 10 mg Size: 1 mg, 5 mg

Taraxerone Tenuifolin Cat. No.: HY-N1177 Cat. No.: HY-N0702

Taraxerone is isolated from Sedum Tenuifolin is a triterpene isolated from Polygala sarmentosum. Taraxerone enhances effects on tenuifolia Willd, has neuroprotective alcohol dehydrogenase (ADH) and acetaldehyde effects. Tenuifolin reduces Aβ secretion by

dehydrogenase (ALDH) activities with EC50 inhibiting β-secretase. values of 512.42 and 500.16 μM, respectively.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

62 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Tenuigenin Terpinen-4-ol (Senegenin) Cat. No.: HY-N0802 (4-Carvomenthenol) Cat. No.: HY-W017316

Tenuigenin is a major active component isolated Terpinen-4-ol (4-Carvomenthenol), a naturally from the root of the Chinese herb Polygala occurring monoterpene, is the main bioactive tenuifolia. Tenuigenin protects against component of tea-tree oil. Terpinen-4-ol S.aureus-induced pneumonia by inhibiting NF-κB suppresses inflammatory mediator production by activation. Tenuigenin has anti-inflammatory activated human monocytes. effect. Purity: 99.24% Purity: >96.0% Clinical Data: No Development Reported Clinical Data: Phase 1 Size: 5 mg, 10 mg, 20 mg Size: 10 mM × 1 mL, 100 mg

Teucvidin Tiamulin Cat. No.: HY-N2525 (Thiamutilin) Cat. No.: HY-B2060

Teucvidin is a diterpenoid from Teucrium Tiamulin (Thiamutilin) is a diterpenic compound species. that widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Toosendanin Tracheloside Cat. No.: HY-N0263 Cat. No.: HY-N1507

Toosendanin, a triterpenoid extracted from the Tracheloside is an antiestrogenic lignin. bark of fruit of Melia toosendan Sieb et Zucc, Tracheloside promotes keratinocyte proliferation possesses analgesic, insecticidal and through ERK1/2 stimulation. Tracheloside is a good anti-inflammatory activities. candidate to promote wound healing.

Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

Transcrocetin Transcrocetin meglumine salt (trans-Crocetin) Cat. No.: HY-N2072 (trans-Crocetin meglumine salt) Cat. No.: HY-42937

Transcrocetin (trans-Crocetin), extracted from Transcrocetin meglumine salt, extracted from saffron (Crocus sativus L.), acts as an NMDA saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. receptor antagonist with high affinity. Transcrocetin (trans-Crocetin) is capable of crossing the blood-brain barrier and reach the central nervous system (CNS). Purity: 98.60% Purity: 95.13% Clinical Data: Phase 2 Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg

Tripterin Triptolide (Celastrol) Cat. No.: HY-13067 (PG490) Cat. No.: HY-32735

Tripterin (Celastrol) is a proteasome inhibitor Triptolide is a diterpenoid triepoxide extracted which potently and preferentially inhibits the from the root of Tripterygium wilfordii with chymotrypsin-like activity of a purified 20S immunosuppressive, anti-inflammatory and proteasome with IC50 of 2.5 μM. antiproliferative effects. Triptolide is a NF-κB activation inhibitor.

Purity: 99.91% Purity: 99.79% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 10 mM × 1 mL, 2 mg, 5 mg, 10 mg, 25 mg, 100 mg

www.MedChemExpress.com 63

Triptonide Triptophenolide (NSC 165677; PG 492) Cat. No.: HY-32736 (Hypolide; (+)-Triptophenolide) Cat. No.: HY-N0475

Triptonide(NSC 165677; PG 492), extracted from Triptophenolide is a colorless crystalline plate Tripterygium wilfordii Hook, inhibited the isolated from ethyl acetate extracts of proliferation of mouse splenocytes induced by Tripterygium wilfordii. suboptimal concentration of concanavalin A or lipopolysaccharide at concentrations of 0.02, 0.1, and 0.5 mg/ml. Purity: 98.65% Purity: 99.93% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Tubeimoside I Tubeimoside II (Tubeimoside-1; Lobatoside-H) Cat. No.: HY-N0890 (Tubeimoside-B) Cat. No.: HY-N0891

Tubeimoside I(Lobatoside-H) is an extract from Tubeimoside II(Tubeimoside-B) is a natural Chinese herbal medicine Bolbostemma paniculatum analogue of oleanane type of triterpenoid saponin; (MAXIM.) FRANQUET (Cucurbitaceae) has been shown show anti-inflammatory, antitumor, and as a potent anti-tumor agent for a variety of antitumor-promoting effects. human cancers.

Purity: 98.03% Purity: 99.70% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg Size: 10 mM × 1 mL, 5 mg, 10 mg

Tubeimoside III Tussilagone Cat. No.: HY-N2542 Cat. No.: HY-N1388

Tubeimoside III, a triterpenoid saponin isolated Tussilagone, a major active component in Tussilago from a Chinese folk medicine"Tubeimu", shows farfara, has anti-inflammatory effect. Tussilagone anti-inflammatory, anti-tumor, anti-tumorigenic ameliorates inflammatory responses in dextran activities, and acute toxicity in vivo. sulphate sodium-induced murine colitis.

Purity: >98% Purity: 99.51% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 20 mg Size: 5 mg, 10 mg, 20 mg

Ursolic acid Ursolic acid acetate (Prunol; Urson; Malol) Cat. No.: HY-N0140 (Acetylursolic acid; 3-Acetylursolic acid) Cat. No.: HY-N2815

Ursolic acid (Prunol) is a natural pentacyclic Ursolic acid acetate (Acetylursolic acid), triterpenoid carboxylic acid, exerts anti-tumor isolated from the aerial roots of Ficus effects and is an effective compound for cancer microcarpa, exhibits cytotoxicity against KB

prevention and therapy. cells with IC50 of 8.4 μM.

Purity: 99.27% Purity: >98% Clinical Data: Phase 2 Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 5 mg, 10 mg, 20 mg

Ursonic acid Uvaol (3-Ketoursolic acid) Cat. No.: HY-N1486 Cat. No.: HY-N1109

Ursolic acid, a naturally occurring triterpenoid, Uvaol, a triterpene present in olives and virgin induces the apoptosis of human cancer cells olive oil, possesses anti-inflammatory properties through multiple signaling pathways. and antioxidant effects. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice.

Purity: >98.0% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg Size: 5 mg, 10 mg

64 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected]

Valencene Valepotriate Cat. No.: HY-N6636 (Valtrate) Cat. No.: HY-N0718

Valencene is a sesquiterpene isolated from Cyperus Valepotriate, isolated from Valeriana rotundus, possesses antiallergic, jatamansi Jones, has anti-epileptic and antimelanogenesis, anti-infammatory, and anti-cancer activities. antioxidant activitivies.

Purity: >98% Purity: 97.24% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg

Verbenalin Verbenone Cat. No.: HY-N2014 ((-)-Verbenone) Cat. No.: HY-N6661

Verbenalin is Verbena glycoside, with Verbenone ((-)-Verbenone) is a natural terpene in anti-inflammatory, anti-fungal anti-virus leaves of the tree, Suregada zanzibariensis Verdc. activities. Verbenalin can be used for the Verbenone has anti-aggregation pheromone and research of prostatitis. Verbenalin can reduce interrupts the attraction of bark beetles to their cerebral ischemia-reperfusion injury. aggregation pheromones.

Purity: 99.47% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg, 25 mg Size: 1 mg, 5 mg

Verminoside Vinaginsenoside R4 Cat. No.: HY-N1094 Cat. No.: HY-N4265

Verminoside is an iridoid isolated from Kigelia Vinaginsenoside R4, isolated from the leaves of africana, exhibits anti-inflammatory and remarkable hydroponic Panax ginseng. It has an inhibitory antioxidant activity with a radical-scavenging effect on melanin biosynthesis without any activity of 2.5 μg/mL. The genotoxicity of cytotoxic effects on the melan-a cells, and Verminoside on human lymphocytes is associated enhances the depigmentation on the zebrafish. with elevated levels of PARP-1 and p53 proteins. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Vinaginsenoside R8 Waltonitone Cat. No.: HY-N4266 Cat. No.: HY-128366

Vinaginsenoside R8, a triterpenoid glycoside Waltonitone is a ursane-type pentacyclic isolated from the rhizomes of Panacis majoris. triterpene isolated from Gentian waltonii Vinaginsenoside R8 displays activities against Burkill. Waltonitone significantly inhibits adenosine diphosphate (ADP)-induced platelet hepatocellular carcinoma cells growth and induces aggregation (IC50=25.18 μM). apoptosis in vitro and in vivo.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg

Wilforgine Wilforlide A Cat. No.: HY-N1072 (Regelide; Abruslactone A) Cat. No.: HY-N0476

Wilforgine is a bioactive sesquiterpene alkaloid Wilforlide A is a natural product, separated from in Tripterygium wilfordii Hook. F. the ethanolic extract of tripterygium wilfordii.

Purity: >98% Purity: >99.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg, 10 mg

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Xanthatin Xanthorrhizol Cat. No.: HY-N3032 Cat. No.: HY-112657

Xanthatin is isolated from Xanthium Xanthorrhizol, isolated from Curcuma strumarium leaves. xanthorrhiza Roxb, is a potential antibacterial agent.

Purity: 99.79% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg, 100 mg Size: 1 mg, 5 mg

Yamogenin Yuanhuacine (Neodiosgenin) Cat. No.: HY-N2078 (Gnidilatidin) Cat. No.: HY-N7225

Yamogenin (Neodiosgenin) is a diastereomer of Yuanhuacine (Gnidilatidin), a daphnane diterpenoid diosgenin. Yamogenin (Neodiosgenin) antagonizes from the flowers of Daphne genkwa with extensive the activation of the liver X receptor (LXR) in anti-tumor activity. Yuanhuacine is a DNA-damaging luciferase ligand assay. agent with orally active.

Purity: 99.20% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 25 mg Size: 1 mg

Zingiberen Newsaponin Zingiberene Cat. No.: HY-N2282 (α-Zingiberene; (-)-Zingiberene) Cat. No.: HY-14618

Zingiberen Newsaponin is extracted from isolated Zingiberene (α-Zingiberene) is a monocyclic from Dioscorea zingiberensis. Zingiberen Newsaponin sesquiterpene which is the predominant constituent exhibits induction effect on platelet aggregation. of ginger with oil content (Zingiber officinale). Neuroprotective potential. Zingiberene triggers autophagy. Anticancer activity.

Purity: >98% Purity: >97.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg, 10 mg Size: 5 mg

Zingibroside R1 Ziyuglycoside I Cat. No.: HY-N6924 Cat. No.: HY-N0331

Zingibroside R1 is dammaranae-type triterpenoid Ziyuglycoside I isolated from S. officinalis root, saponin, isolated from rhizomes, taproots, and has anti-wrinkle activity, and increases the lateral roots of Panax japonicas C. A. Meyer, shows expression of type I collagen. Ziyuglycoside I excellent anti-tumor effects as well as could be used as an active ingredient for anti-angiogenic activity. Zingibroside R1 cosmetics. possesses some anti-HIV-1 activity. Purity: >98% Purity: 98.51% Clinical Data: Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 10 mM × 1 mL, 5 mg, 10 mg, 25 mg, 50 mg

Ziyuglycoside II α-Amyrin acetate Cat. No.: HY-N0332 Cat. No.: HY-N2842

Ziyuglycoside II is a triterpenoid saponin α-Amyrin acetate, a natural triterpenoid, has compound extracted from Sanguisorba officinalis L.. anti-inflammatory activity, antispasmodic profile Ziyuglycoside II induces reactive oxygen species and the relaxant effect. (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect.

Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 5 mg

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α-Humulene α-Terpineol (Humulene; α-Caryophyllene) Cat. No.: HY-N6968 Cat. No.: HY-N5142

α-Humulene is a main constituent of Tanacetum α-Terpineol is isolated from Eucalyptus globulus vulgare L. (Asteraceae) essential oil with Labill, exhibits strong antimicrobial activity anti-inflammation (IC50=15±2 µg/mL). α-Humulene against periodontopathic and cariogenic bacteria. inhibits COX-2 and iNOS expression. α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 100 mg

α-Thujone β-Carotene Cat. No.: HY-121618 (Provitamin A; beta-Carotene) Cat. No.: HY-N0411

α-Thujone is a monoterpene isolated from Thuja β-Carotene (Provitamin A) is an organic compound occidentalis essential oil with potent anti-tumor and classified as a terpenoid. It is a precursor activities. α-Thujone is a reversible modulator of (inactive form) of vitamin A. the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. Purity: >98% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 50 mg, 100 mg

β-Caryophyllene ((-)-(E)-Caryophyllene; (−)-β-caryophyllene; β-Cryptoxanthin (−)-trans-Caryophyllene) Cat. No.: HY-N1415 ((3R)-β-Cryptoxanthin) Cat. No.: HY-108059

β-Caryophyllene is a CB2 receptor agonist. β-Cryptoxanthin ((3R)-β-Cryptoxanthin), isolated from Satsuma mandarin orange, is an oxygenated carotenoid and a potent antioxidant. β-Cryptoxanthin has an anti-stress effect.

Purity: >95.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 500 mg Size: 1 mg, 5 mg

β-Elemene β-Elemonic acid ((-)-β-Elemene; Levo-β-elemene) Cat. No.: HY-107324 Cat. No.: HY-N2454

β-Elemene ((-)-β-Elemene; Levo-β-elemene) is β-Elemonic acid is a triterpene isolated from isolated from natural plant Curcuma wenyujin Boswellia papyrifera. β-Elemonic acid induces with an antitumor activity. β-Elemene can induce cell apoptosis, reactive oxygen species (ROS) and cell apoptosis. COX-2 expression and inhibits prolyl endopeptidase. β-Elemonic acid exhibits anticancer and anti-inflammatory effects. Purity: 96.35% Purity: >99.0% Clinical Data: Phase 3 Clinical Data: No Development Reported Size: 10 mM × 1 mL, 5 mg, 10 mg, 50 mg Size: 5 mg, 10 mg, 20 mg

β-Hederin Cat. No.: HY-N7489

β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively. Purity: >97.0% Clinical Data: No Development Reported Size: 1 mg, 5 mg

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