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Terpenoids and Glycosides Terpenoids and Glycosides The terpenoids are a large and diverse class of naturally occurring organic chemicals, derived from five-carbon isoprene units assembled and modified in thousands of ways. Most are multicyclic structures that differ from one another not only in functional groups but also in their basic carbon skeletons. They can be classified according to the number of isoprene units used: Hemiterpenoids, Monoterpenoids, Sesquiterpenoids, Diterpenoids, Sesterterpenoids, Triterpenoids, Tetraterpenoids. These lipids can be found in all classes of living things, and are the largest group of natural products. Plant terpenoids are used extensively for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. www.MedChemExpress.com 1 Terpenoids and Glycosides Inhibitors & Modulators (+)-Borneol (+)-Camphor (d-Borneol) Cat. No.: HY-N1368A (D-(+)-Camphor; (1R)-(+)-Camphor) Cat. No.: HY-B1173 (+)-Borneol (d-Borneol) is a natural bicyclic (+)-Camphor is an ingredient in cooking, and as an monoterpene used for analgesia and anesthesia in embalming fluid for medicinal purposes,. traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM. Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 100 mg Size: 10 mM × 1 mL, 500 mg (+)-Dehydroabietic acid (+)-Longifolene Cat. No.: HY-N2546 Cat. No.: HY-N6662 (+)-Dehydroabietic acid is a diterpenoid. (+)-Longifolene is a sesquiterpenoid and a (+)-Dehydroabietic acid can be used for the metabolite in rabbits. (+)-Longifolen is converted acrylamide Hydrogel synthesis. to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mg, 25 mg, 50 mg, 100 mg Size: 1 mg, 5 mg (+)-trans-Isolimonene (-)-Altenuene Cat. No.: HY-N7250 Cat. No.: HY-N6713 (+)-trans-Isolimonene is a natural monoterpene (-)-Altenuene is a heptaketide isolated from an isolated from essential oil. endolichenic fungal strain Nigrospora sphaerica. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg (-)-Borneol (-)-Cedrene (L-Borneol) Cat. No.: HY-N1368B (α-cedrene) Cat. No.: HY-135190 (-)-Borneol has a highly efficacious positive (-)-Cedrene (α-cedrene) is a sesquiterpene modulating action at GABA receptor with an EC50 constituent of cedarwood oils, with anti-leukemic, of 237 μM. antimicrobial and anti-obesity activities. Purity: >98.0% Purity: >98.0% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 1 mL, 5 mL (-)-Fenchone (-)-Limonene Cat. No.: HY-N5132 ((S)-(-)-Limonene) Cat. No.: HY-Z0478 (-)-Fenchone, a bicyclic monoterpene, is widely (-)-Limonene ((S)-(-)-Limonene) is a monoterpene distributed in plants and found in essential oils found in many pine-needle oils and in turpentine. from Thuja occidentalis. (-)-Limonene can induce a mild bronchoconstrictive effect. Purity: >98.0% Purity: >95.0% Clinical Data: No Development Reported Clinical Data: Launched Size: 10 mM × 1 mL, 500 mg Size: 10 mM × 1 mL, 100 mg 2 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected] (-)-Menthol (-)-α-Pinene Cat. No.: HY-75161 Cat. No.: HY-N0549 (-)-Menthol is a key component of peppermint oil (-)-α-Pinene is a monoterpene and shows sleep that binds and activates transient receptor enhancing property through a direct binding to potential melastatin 8 (TRPM8), a GABAA-benzodiazepine (BZD) receptors by acting as Ca2+-permeable nonselective cation channel, to a partial modulator at the BZD binding site. 2+ increase [Ca ]i. Antitumor activity. Purity: >98.0% Purity: 99.63% Clinical Data: Launched Clinical Data: No Development Reported Size: 10 mM × 1 mL, 500 mg, 1 g Size: 10 mM × 1 mL, 100 mg, 1 g, 5 g (-​)​-​α-​Terpineol (20R)-Ginsenoside Rh1 ((S​)​-​α-​Terpineol) Cat. No.: HY-N1467 Cat. No.: HY-N1400 (-)-α-Terpineol ((S)-α-Terpineol), a monoterpene (20R)-Ginsenoside Rh1, the R isomer of Ginsenoside compound, is one of important aroma compounds in Rh1 isolated from Panax Ginseng, inhibits the white wines. thrombin-induced conversion of fibrinogen to fibrin. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 5 mg, 10 mg, 20 mg (20R)-Protopanaxadiol (R)-(+)-Citronellal Cat. No.: HY-N2040 ((+)-Citronellal) Cat. No.: HY-111664 (20R)-Protopanaxadiol is a triterpenoid saponin (R)-(+)-Citronellal, isolated from citrus, metabolite of 20(R)-ginsenoside Rg3 in black lavender and eucalyptus oils, is a monoterpenoid ginseng. (20R)-Protopanaxadiol exhibits anti-tumor and main component of citronellal oil with a activity and cytotoxicity, and potently inhibits distinct lemon scent. A flavouring agent. Used for the growth of Helicobacter pylori. insect repellent and antifungal properties. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg (R)-Citronellol (Rac)-β-Chamigrenic acid (D-Citronellol; (R)-(+)-β-Citronellol) Cat. No.: HY-124257 Cat. No.: HY-N7606 (R)-Citronellol (D-Citronellol) is an alcoholic (Rac)-β-Chamigrenic acid is a racemate of monoterpene found in geranium essential oil. β-Chamigrenic acid. β-Chamigrenic acid is an (R)-Citronellol inhibits degranulation of mast sesquiterpenoid isolated from S.chinensis. cells and does not affect caffeine bitterness perception. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 1 mg (S)-(−)-Perillyl alcohol (S)​-​(-​)​-​Citronellal Cat. No.: HY-116514 ((-​)​-​Citronellal) Cat. No.: HY-111664A (S)-(−)-Perillyl alcohol is a monoterpene found in (S)-(-)-Citronellal ((-)-Citronellal) is a lavender, inhibits farnesylation of Ras, monoterpenoid compound found in Corymbia upregulates the mannose-6-phosphate receptor and citriodora and Cymbopogon nardus essential oils. induces apoptosis. Anti-cancer activity. Purity: >98.0% Purity: >98% Clinical Data: No Development Reported Clinical Data: Size: 10 mM × 1 mL, 100 mg Size: 1 mg, 5 mg www.MedChemExpress.com 3 1,4-Cineole 10-Deacetylbaccatin III Cat. No.: HY-N7117 Cat. No.: HY-16565 1,4-Cineole is a widely distributed, natural, 10-Deacetylbaccatin-III is an intermediate for oxygenated monoterpene. 1,4-Cineole, present in taxol analog preparations. IC50 value: Target: eucalyptus oil, activates both human TRPM8 and Taxols have exhibit antitumor agents. Several of human TRPA1. these taxols can be synthesized from 10- Deacetylbaccatin-III. Purity: >95.0% Purity: 95.05% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 100 mg Size: 10 mM × 1 mL, 100 mg, 200 mg, 500 mg 11-oxo-mogroside V 11-Oxomogroside IIe Cat. No.: HY-N0501 Cat. No.: HY-N6852 11-oxo-mogroside V is a natural sweetener, 11-Oxomogroside IIe is a triterpene glycoside isolated from the fruits of Momordica isolated from Siraitia grosvenori. grosvenori, exhibits strong antioxidant activity. Purity: 99.69% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg Size: 5 mg, 10 mg 11-​Keto-​beta-​boswellic acid 11-​Oxomogroside III (11-Keto-β-boswellic acid) Cat. No.: HY-N2056 Cat. No.: HY-N6921 11-Keto-beta-boswellic acid (11-Keto-β-boswellic 11-Oxomogroside III is a cucurbitane triterpene acid) is a pentacyclic triterpenic acid of the glycoside isolated from in Siraitia grosvenorii oleogum resin from the bark of the Boswellia fruits. serrate tree, popularly known as Indian Frankincense. Purity: 99.96% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 5 mg, 10 mg Size: 1 mg, 5 mg 12-Hydroxyganoderic Acid D 14-Deoxy-11,12-didehydroandrographolide Cat. No.: HY-N7021 (14-dehydro Andrographolide; AP10) Cat. No.: HY-N1490 12-Hydroxyganoderic Acid D is a triterpenoid 14-Deoxy-11,12-didehydroandrographolide is an extracted from Ganoderma lucidum. analogue of Andrographolide that can be isolated from A. paniculata. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation. Purity: >98% Purity: 99.55% Clinical Data: Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 10 mM × 1 mL, 1 mg, 5 mg, 10 mg, 25 mg 15-Acetyl-deoxynivalenol 16α-Hydroxydehydrotrametenolic acid Cat. No.: HY-N6683 (3β,16α-Dihydroxylanosta-7,9(11),24-trien-21-oic acid) Cat. No.: HY-N2990 15-Acetyl-deoxynivalenol is a highly toxic 16α-Hydroxydehydrotrametenolic acid is a trichothecene found in cereals, and a metabolite triterpene Acid in fermented mycelia of edible of deoxynivalenol, exhibits toxicity to HepG2 fungus Poria cocos. cells. Purity: >98% Purity: >98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 1 mg, 5 mg Size: 1 mg, 5 mg 4 Tel: 609-228-6898 Fax: 609-228-5909 Email: [email protected] 18β-Glycyrrhetinic acid 2,2'-Anhydrouridine Cat. No.: HY-N0180 (2,2'-Cyclouridine; O2,2'-Cyclouridine) Cat. No.: HY-W012313 18β-Glycyrrhetinic acid is the major bioactive 2,2'-Anhydrouridine is used for anticancer and component of Glycyrrhizae Radix and possesses antiviral research. anti-ulcerative, anti-inflammatory
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