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(12) Patent Application Publication (10) Pub. No.: US 2006/0110428A1 De Juan Et Al
US 200601 10428A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2006/0110428A1 de Juan et al. (43) Pub. Date: May 25, 2006 (54) METHODS AND DEVICES FOR THE Publication Classification TREATMENT OF OCULAR CONDITIONS (51) Int. Cl. (76) Inventors: Eugene de Juan, LaCanada, CA (US); A6F 2/00 (2006.01) Signe E. Varner, Los Angeles, CA (52) U.S. Cl. .............................................................. 424/427 (US); Laurie R. Lawin, New Brighton, MN (US) (57) ABSTRACT Correspondence Address: Featured is a method for instilling one or more bioactive SCOTT PRIBNOW agents into ocular tissue within an eye of a patient for the Kagan Binder, PLLC treatment of an ocular condition, the method comprising Suite 200 concurrently using at least two of the following bioactive 221 Main Street North agent delivery methods (A)-(C): Stillwater, MN 55082 (US) (A) implanting a Sustained release delivery device com (21) Appl. No.: 11/175,850 prising one or more bioactive agents in a posterior region of the eye so that it delivers the one or more (22) Filed: Jul. 5, 2005 bioactive agents into the vitreous humor of the eye; (B) instilling (e.g., injecting or implanting) one or more Related U.S. Application Data bioactive agents Subretinally; and (60) Provisional application No. 60/585,236, filed on Jul. (C) instilling (e.g., injecting or delivering by ocular ion 2, 2004. Provisional application No. 60/669,701, filed tophoresis) one or more bioactive agents into the Vit on Apr. 8, 2005. reous humor of the eye. Patent Application Publication May 25, 2006 Sheet 1 of 22 US 2006/0110428A1 R 2 2 C.6 Fig. -
Effect of the Gaba Derivative Succicard on the Lipid and Carbohydrate Metabolism in the Offspring of Rats with Experimental Preeclampsia in Early and Late Ontogeny
ОРИГИНАЛЬНАЯ СТАТЬЯ DOI: 10.19163/2307-9266-2020-8-5-325-335 EFFECT OF THE GABA DERIVATIVE SUCCICARD ON THE LIPID AND CARBOHYDRATE METABOLISM IN THE OFFSPRING OF RATS WITH EXPERIMENTAL PREECLAMPSIA IN EARLY AND LATE ONTOGENY E.A. Muzyko1, V.N. Perfilova1, A.A. Nesterova2, K.V. Suvorin1, I.N. Tyurenkov1 1 Volgograd State Medical University 1, Pavshikh Bortsov Sq., Volgograd, Russia, 400131 2 Pyatigorsk Medical and Pharmaceutical Institute – branch of Volgograd State Medical University 11, Kalinin Ave., Pyatigorsk, Russia, 357532 E-mail: [email protected] Received 02 Jan 2019 Accepted 08 Jul 2020 Maternal preeclampsia can bring about metabolic disorders in the offspring at different stages of ontogeny. Up to date, no ways of preventive pharmacological correction of lipid and carbohydrate metabolism disorders developing in different peri- ods of ontogeny in the children born to mothers with this pregnancy complication, have been developed. The aim of the experiment was to study the effect of the gamma-aminobutyric acid derivative succicard (22 mg/kg) and its reference drug pantogam (50 mg) administered per os in the course of treatment in puberty (from 40 to 70 days after birth), on the parameters of lipid and carbohydrate metabolism in the offspring of the rats with experimental preeclampsia, in dif- ferent periods of ontogeny. Materials and methods. To assess the activity of lipid and carbohydrate metabolism in the offspring, an oral glucose toler- ance test was performed at 40 days, 3, 6, 12 and 18 months of age. The level of glycosylated hemoglobin was measured at the age of 6, 12, and 18 months, and the concentrations of total cholesterol, high-density lipoprotein cholesterol and tri- glycerides were tested at 40 days, 3, 6, 12, and 18 months of age. -
(12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness Et Al
USOO6264,917B1 (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness et al. (45) Date of Patent: Jul. 24, 2001 (54) TARGETED ULTRASOUND CONTRAST 5,733,572 3/1998 Unger et al.. AGENTS 5,780,010 7/1998 Lanza et al. 5,846,517 12/1998 Unger .................................. 424/9.52 (75) Inventors: Jo Klaveness; Pál Rongved; Dagfinn 5,849,727 12/1998 Porter et al. ......................... 514/156 Lovhaug, all of Oslo (NO) 5,910,300 6/1999 Tournier et al. .................... 424/9.34 FOREIGN PATENT DOCUMENTS (73) Assignee: Nycomed Imaging AS, Oslo (NO) 2 145 SOS 4/1994 (CA). (*) Notice: Subject to any disclaimer, the term of this 19 626 530 1/1998 (DE). patent is extended or adjusted under 35 O 727 225 8/1996 (EP). U.S.C. 154(b) by 0 days. WO91/15244 10/1991 (WO). WO 93/20802 10/1993 (WO). WO 94/07539 4/1994 (WO). (21) Appl. No.: 08/958,993 WO 94/28873 12/1994 (WO). WO 94/28874 12/1994 (WO). (22) Filed: Oct. 28, 1997 WO95/03356 2/1995 (WO). WO95/03357 2/1995 (WO). Related U.S. Application Data WO95/07072 3/1995 (WO). (60) Provisional application No. 60/049.264, filed on Jun. 7, WO95/15118 6/1995 (WO). 1997, provisional application No. 60/049,265, filed on Jun. WO 96/39149 12/1996 (WO). 7, 1997, and provisional application No. 60/049.268, filed WO 96/40277 12/1996 (WO). on Jun. 7, 1997. WO 96/40285 12/1996 (WO). (30) Foreign Application Priority Data WO 96/41647 12/1996 (WO). -
ABSTRACT GYLYUK, ALEXEY. Properties of Gallium Nitride-Microorganism Interfaces
ABSTRACT GYLYUK, ALEXEY. Properties of Gallium Nitride-Microorganism Interfaces. (Under the direction of Dr. Albena Ivanisevic). A wide portfolio of advanced programmable materials and structures has been developed for biological applications in the last two decades. In particular, due to their unique properties, semiconducting materials have been utilized in areas of biocomputing, implantable electronics, and healthcare. As a new concept of such programmable material design, biointerfaces based on inorganic semiconducting materials as substrates introduce unconventional paths for bioinformatics and biosensing. In particular, understanding how the properties of a substrate can alter microbial biofilm behavior enables researchers to better characterize and thus create programmable biointerfaces with necessary characteristics on-demand. During the preliminary research stage, the most promising semiconductor material types along with target microorganisms were identified and subsequently utilized for further studies. Gallium-based surfaces (particularly, GaN with different doping levels) were chosen as the most promising semiconducting materials to be used in inorganic substrate-microorganism biointerfaces. The work was based on the hypothesis that they can be tailored to induce controllable microorganism behavior under specific user defined external conditions. At this stage of the work Pseudomonas aeruginosa was the test organism in the first two experimental parts of the dissertation work. As a the typical in-hospital infection, P.aeruginosa possesses high survivability and enhanced abilities to form resilient biofilms on various surfaces. These factors allowed us to perform a set of studies that enable to create GaN-P.aeruginosa biointerfaces, characterize them and identify factors triggering the morphological and physiological reactions of formulated structures. The final stage of the dissertation project involved utilization of the yeast culture Saccharomyces cerevisiae which expanded the class of microorganisms used in the dissertation work. -
Method Development and Validation of an HPLC Assay for the Detection of Hopantenic Acid in Human Plasma and Its Application to a Pharmacokinetic Study on Volunteers
Acta Chromatographica 23(2011)3, 403–414 DOI: 10.1556/AChrom.23.2011.3.3 Method Development and Validation of an HPLC Assay for the Detection of Hopantenic Acid in Human Plasma and Its Application to a Pharmacokinetic Study on Volunteers O.N. POZHARITSKAYA1, V.M. KOSMAN1, M.V. KARLINA1, A.N. SHIKOV1,2*, V.G. MAKAROV1,2, AND G.I. DJACHUK1,2 1Saint-Petersburg Institute of Pharmacy, 47/5, Piskarevsky pr., 195067 St. Petersburg, Russia 2Saint-Petersburg State Medical Academy Named After I.I. Mechnikov, 47/33, Piskarevsky pr., 195067 St. Petersburg, Russia E-mail: [email protected] Summary. A reliable and sensitive reversed-phase high performance liquid chromatog- raphy (RP-HPLC) with ultraviolet (UV) detection method was developed and validated for the quantification of hopantenic acid in human plasma. Hopantenic acid, with proto- catechuic acid as the internal standard (IS), was extracted from plasma samples using a liquid–liquid extraction with methanol. A chromatographic separation was achieved on a Luna C18 column (4.6 mm × 150 mm, 5-μm particle size) and precolumn of the same sorbent (2.0 mm). An isocratic elution, at a flow rate of 1.0 mL min−1, was used with a mobile phase consisting of acetonitrile, water, and 0.03% trifluoroacetic acid. The UV de- tector was set to 205 nm. The elution times for hopantenic acid and IS were ~4.3 and 5.4 min, respectively. The calibration curve of hopantenic acid was linear (r > 0.9994) over the range of 0.5–100 μg mL−1 in human plasma. The limit of detection and limit of quantification for hopantenic acid were 0.034 and 0.103 μg mL−1, respectively. -
Pharmaceutical Appendix to the Tariff Schedule 2
Harmonized Tariff Schedule of the United States (2007) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE Harmonized Tariff Schedule of the United States (2007) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 2 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. ABACAVIR 136470-78-5 ACIDUM LIDADRONICUM 63132-38-7 ABAFUNGIN 129639-79-8 ACIDUM SALCAPROZICUM 183990-46-7 ABAMECTIN 65195-55-3 ACIDUM SALCLOBUZICUM 387825-03-8 ABANOQUIL 90402-40-7 ACIFRAN 72420-38-3 ABAPERIDONUM 183849-43-6 ACIPIMOX 51037-30-0 ABARELIX 183552-38-7 ACITAZANOLAST 114607-46-4 ABATACEPTUM 332348-12-6 ACITEMATE 101197-99-3 ABCIXIMAB 143653-53-6 ACITRETIN 55079-83-9 ABECARNIL 111841-85-1 ACIVICIN 42228-92-2 ABETIMUSUM 167362-48-3 ACLANTATE 39633-62-0 ABIRATERONE 154229-19-3 ACLARUBICIN 57576-44-0 ABITESARTAN 137882-98-5 ACLATONIUM NAPADISILATE 55077-30-0 ABLUKAST 96566-25-5 ACODAZOLE 79152-85-5 ABRINEURINUM 178535-93-8 ACOLBIFENUM 182167-02-8 ABUNIDAZOLE 91017-58-2 ACONIAZIDE 13410-86-1 ACADESINE 2627-69-2 ACOTIAMIDUM 185106-16-5 ACAMPROSATE 77337-76-9 -
Marrakesh Agreement Establishing the World Trade Organization
No. 31874 Multilateral Marrakesh Agreement establishing the World Trade Organ ization (with final act, annexes and protocol). Concluded at Marrakesh on 15 April 1994 Authentic texts: English, French and Spanish. Registered by the Director-General of the World Trade Organization, acting on behalf of the Parties, on 1 June 1995. Multilat ral Accord de Marrakech instituant l©Organisation mondiale du commerce (avec acte final, annexes et protocole). Conclu Marrakech le 15 avril 1994 Textes authentiques : anglais, français et espagnol. Enregistré par le Directeur général de l'Organisation mondiale du com merce, agissant au nom des Parties, le 1er juin 1995. Vol. 1867, 1-31874 4_________United Nations — Treaty Series • Nations Unies — Recueil des Traités 1995 Table of contents Table des matières Indice [Volume 1867] FINAL ACT EMBODYING THE RESULTS OF THE URUGUAY ROUND OF MULTILATERAL TRADE NEGOTIATIONS ACTE FINAL REPRENANT LES RESULTATS DES NEGOCIATIONS COMMERCIALES MULTILATERALES DU CYCLE D©URUGUAY ACTA FINAL EN QUE SE INCORPOR N LOS RESULTADOS DE LA RONDA URUGUAY DE NEGOCIACIONES COMERCIALES MULTILATERALES SIGNATURES - SIGNATURES - FIRMAS MINISTERIAL DECISIONS, DECLARATIONS AND UNDERSTANDING DECISIONS, DECLARATIONS ET MEMORANDUM D©ACCORD MINISTERIELS DECISIONES, DECLARACIONES Y ENTEND MIENTO MINISTERIALES MARRAKESH AGREEMENT ESTABLISHING THE WORLD TRADE ORGANIZATION ACCORD DE MARRAKECH INSTITUANT L©ORGANISATION MONDIALE DU COMMERCE ACUERDO DE MARRAKECH POR EL QUE SE ESTABLECE LA ORGANIZACI N MUND1AL DEL COMERCIO ANNEX 1 ANNEXE 1 ANEXO 1 ANNEX -
Individual Members from Adhering Countries
INDIVIDUAL MEMBERS FROM ADHERING COUNTRIES Downloaded from https://www.cambridge.org/core. IP address: 170.106.202.226, on 25 Sep 2021 at 08:44:09, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0251107X00008865 MEMBERSHIP 339 ALGERIA ABDELATIF TOUFIK AMARMAKHLOUF ARGENTINA ABADI MARIO FORTE JUAN CARLOS DR MORRELL NIDIA DR AGUERO ESTELA L DR GARCIA BEATR1Z ELENA MURIEL HERNAN ALTAVISTA CARLOS A DR GARCIA LAMBAS DIEGO DR MUZZIO JUAN C PROF AQUILANO ROBERTO OSCAR DR GIACANI ELSA BEATRIZ DR NIEMELAVIRPISDR ARIAS ELISA FELICITAS DR GOMEZ MERCEDES DR NUNEZ JOSUE ARTURO ARNAL MARCELO EDMUNDO DR HERNANDEZ CARLOS ALBERTO OLANO CARLOS ALBERTO DR AZCARATE ISMAEL N DR IANNINI GUALBERTO DR ORELLANA ROSA BEATRIZ DR BAJAJA E DR LAPASSET EMILIO DR ORSATTI ANA M DR BARBA RODOLFO HECTOR DR LEVATO ORLANDO HUGO DR PERDOMO RAUL LIC BASSINO LILIA P DR LOPEZ CARLOS LIC PIACENTINI RUBEN DR BENVENUTO OMAR DR LOPEZ GARCIA ZULEMA L DR POEPPEL WOLFGANG G L DR BRANDI ELISANDE ESTELA DR LOPEZ JOSE A 1NG RABOLLI MONICA DR BRANHAM RICHARD L JR LOPEZ-GARCIA FRANCISCO DR RINGUELET ADELA E DR CAPPA DE NICOLAU CRISTINA LUNAHOMEROGDR ROVIRA MARTA GRACIELA CARRANZA GUSTAVO J DR MACHADO MARCOS SAHADEJORGE PROF CASTAGNINO MARIO DR MALARODA STELLA M DR SISTERO ROBERTO F DR CIDALE LYDIA SONIA MANDRINI CRISTINA HEMILSE SOLIVELLA GLADYS R LIC CLARIA JUAN DR MANRIQUE WALTER T PROF VAZQUEZ RUBEN ANGEL DR COLOMB FERNANDO R DR MARABINI RODOLFO JOSE ING VEGA E IRENE DR COSTA ANDREA MARRACO HUGO G DR VERGNE MARIA -
Sezione E - Intermediari Assicurativi a Titolo Accessorio
Sezione E - Intermediari assicurativi a titolo accessorio aggiornato al 23/set/2021 Elenco Società N° Iscrizione Ragione sociale Sede Legale E000689599 ESSE ESSE GARAGE SRL VIA ANGELO CALZOLARI 61 - 43126PARMA(PR) E000689600 MILLENIUM CAR SRL VLE DELLA LIBERTA SNC - 84022CAMPAGNA(SA) E000689844 ART SRL VIA FLAVIA 120 - 34147TRIESTE(TS) E000689992 MORAUTO SRL VIA SALARIA 167 - 00015MONTEROTONDO(RM) E000690015 AUTOEXPO SRL VIA CRISTOFORO COLOMBO 5860 - 42017NOVELLARA(RE) E000690736 AM AUTO SRLS VIA PASUBIO 19 - 35018SAN MARTINO DI LUPARI(PD) E000690737 THEOREMA SRL STRADA DELLA REPUBBLICA 41 - 43121PARMA(PR) E000690913 FAENZA CARAVAN SRL VIA EMILIA PONENTE 76C - 48018FAENZA(RA) E000690943 LDR SRL VIA MARZABOTTO 16 - 40133BOLOGNA(BO) E000690944 SAI SRLS VIA SANTA MARIA 3 - 26010CHIEVE(CR) E000691035 CI.PA. SRL VIA EMANUELE FILIBERTO 6 - 20149MILANO(MI) E000691036 RENTAL PLUS SRL VIA PRAGA 5 - 38121TRENTO(TN) E000691037 AMC AUTO SRL VIA STABIA 474 - 80057SANT'ANTONIO ABATE(NA) E000691038 1000 MIGLIA S SRL CORSO TERESIO BORSALINO 19 - 15121ALESSANDRIA(AL) E000691447 CASCINO ANGELO & C. SNC VIA CRISONE 24 - 90018TERMINI IMERESE(PA) E000691489 ROYAL CAFE TWIN VIA MESULA 12 - 00158ROMA(RM) E000691642 L' AUTOMOBILE SRLS CORSO ARNALDO LUCCI 96 - 80142NAPOLI(NA) E000691644 BLUCARS SRL UNIPERSONALE VIA GELA 258 - 92027LICATA(AG) E000691787 ROMANO DI BUONACCORSI DANIELE VIA BALDASSARRE BIASSA 19 - 19121LA SPEZIA(SP) E000691789 FOURWHEELS SRL VIALE SANTUARIO 20 - 20831SEREGNO(MB) E000691925 GABRITOUR SAS DI MONESE ALESSIA & C. VIA BRUNELLESCHI, 16 -
Salto in Alto – Donne
www.sportolimpico.it SALTO IN ALTO – DONNE Tutte le prestazioni fino a 1.94 [141] Aggiornamento: fine stagione 2020 prestazione ottenuta ai Giochi Olimpici prestazione ottenuta ai Campionati Mondiali prestazione ottenuta ai Campionati Europei Al 31 Dic 1950 Al 31 Dic 2000 1.56 Ondina Valla (21) 5 Set 37 2.01 Sara Simeoni (25) 4 Ago 78 1.55 Esther Palmesino (22) 7 Mag 49 1.98i Antonella Bevilacqua (23) 28 Feb 94 1.55 Gianna Jannoni (25) 31 Lug 49 1.95 Francesca Bradamante (25) 23 Mag 98 1.54 Claudia Testoni (21) 37 Set 36 1.92 Sandra Dini (23) 14 Giu 81 1.53 Silvana Pierucci (19) 19 Set 48 1.92 Daniela Galeotti (22) 3 Lug 99 1.52 Irene Bettinelli (28) 4 Mag 50 1.91 Donatella Bulfoni (23) 26 Lug 81 1.51 Modesta Puhar (20) 17 Lug 38 1.91 Stefania Cadamuro (21) 7 Giu 00 1.50 Marcella Sannazzaro 15 Ott 39 1.90 Barbara Fiammengo (16) 17 Set 83 1.50 Gina Spaggiari (23) 7 Lug 40 1.90i Alessandra Fossati (23) 5 Feb 86 1.50 Vanda Vettori 15 Mag 41 1.90 Roberta Bugarini (24) 2 Ago 93 1.50 Sara Aldrovandi 22 Mag 41 1.50 Caterina Gallo (18) 28 Set 41 1.50 Margherita Hach (20) 3 Mag 42 1.50 Anna Maria Ramella 31 Mag 42 1.50 Rosetta Cavazzini 18 Mag 50 Al 31 Dic 2018 2.04i Antonietta DI MARTINO (33) 1-6-78 1) Banská Bystrica, Int. 9 Feb 11 (2.04i/3, 2.02i/1, 2.00i/1, 1.96i/1, 1.92i/1, 1.89i/1, 1.86i, 1.82i/1) …; 2. -
Scientific Report 2014
Scientific Report 2014 Ente Ospedaliero Cantonale Index Preface 5 4. Swiss Clinical Trial Organization 87 4.1 EOC Clinical Trial Unit (CTU-EOC) 88 1. Oncology Institute of Southern Switzerland (IOSI) 9 1.1 Medical Oncology Service 11 5. Scientific Research Advisory Board (ABREOC) 91 1.2 Radiation Oncology Service 12 1.3 Medical Physics Unit of the Radiation Oncology Service 16 6. Official Registry of the EOC clinical studies 95 1.4 Nuclear Medicine Service and PET/CT Centre 17 (EOC Database of clinical studies) 1.5 Palliative Care Service 20 1.6 Haematology Service 21 7. Publications in 2014 99 1.7 Research Division 23 Publications in peer-reviewed journals in 2014 104 1.8 IOSI Nursing Service 31 Publications in non-peer-reviewed journals in 2014 129 Communications at medical conference in 2014 130 2. Neurocenter of Southern Switzerland (NSI) 35 Publications in books in 2014 156 2.1 Multiple Sclerosis Centre 36 2.2 Sleep and Epilepsy group 39 8. Appendices 159 2.3 Movement Disorders Centre 42 Appendix 1 - Research projects funded by ABREOC in 2008 160 2.4 Stroke Centre 45 Appendix 2 - Research projects funded by ABREOC in 2009 162 2.5 Neuropsychology 46 Appendix 3 - Research projects funded by ABREOC in 2010 164 2.6 Neurosurgery 47 Appendix 4 - Research projects funded by ABREOC in 2011 168 2.7 Neuroradiology 50 Appendix 5 - Research projects funded by ABREOC in 2012 - 2013 170 2.8 Neuroanaesthesia 51 Appendix 6 - Research projects funded by ABREOC in 2014 172 2.9 Laboratory for Biomedical Neurosciences (LBN) 52 Appendix 7 - 2014 EOC Projects subject to General Authorisation (AG) 172 3. -
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The Uzbekistan Pavilion Biennale Architettura 2021 Arsenale, Venezia Carlos Casas, Bas Princen Curated by Emanuel Christ & Christoph Gantenbein www.mahallavenice.uz Relaxed The place to be for art lovers! Street art by The London Police in Basel basel.com My Art Guides Lightbox Publishing The 17th edition of the Venice exhibition promoted by TBA21 Architecture Biennale, under Academy “Territorial Agency: Editor-in-Chief Publishers the title of “How will we live Oceans in Transformation” and Mara Sartore Matteo Bartoli together?” opens to the commissions Taloi Havini’s Mara Sartore public on May 22nd and will work “The Soul Expanding Deputy Editor remain open until November Ocean #1”. A must-see are the Carla Ingrasciotta Global PR and Sales 21st. Curator Hashim Sarkis exhibitions at Fondazione Prada Ilaria Malagutti reflects upon the vital role of “Stop Painting”, conceived by Web Editor the architect as both cordial artist Peter Fischli, and “Georg Alessandra Bellomo Press Office convener and custodian of Baselitz: Archinto” at Palazzo Alessandra Bellomo the spatial contract. Today, Grimani, as well as shows by Translations and Proof Readings this theme is more pertinent galleries including Victoria Lara Morrell Techinical Director than ever, in the face of the Miro “Conrad Shawcross”, that Francesca Antona current times we are living in, of Michela Rizzo “Maurizio Graphic Designer and responds to the need of Pellegrin: The Red, The Black Maxim Dosca Web Developer managing the social distancing and the Other” and at the Andrea Serrani imposed on us by the pandemic. Venetian headquarters of the Parisian gallery Alberta Pane the For updated info check our For advertising please write 61 countries are participating exhibition “Gayle Chong Kwan: website myartguides.com to [email protected] this year, 3 of which for the Waste Archipelago”.