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T~Rlrom}\.TOGRAPHY ISSN 0021 -90 t:3 VOL. 524 NO.3 JUNE 13, 1990 Bibliography Section j .JOURNAL OF t~rlROM}\.TOGRAPHY liNTERNATIONAL .JOURNAL ON CHROMATOGRAPHY. ELECTROPHORESIS AND RELATED METHODS EDITORS R. W. Giese (Boston, MA) J. K. Haken (Kensington, N.S.W.) K. Macek (Prague) L. R. Snyder (Orinda, CA) EDITOR, SYMPOSIUM VOLUMES, E. Heftmann (Orinda, CAl EDITORIAL BOARD D. W. Armstrong (Rolla. MO) W. A. Aue (Halifax) P. Bocek (Brno) A. A. Boulton (Saskatoon) P. W. Carr (Minneapolis. MN) N. H. C. Cooke (San Ramon. CAl V. A. Davankov (Moscow) Z. Deyl (Prague) S. Dilli (Kensington. N.S.w.) H. Engelhardt (Saarbrucken) F. Erni (Basle) M. B. Evans (Hatfield) J. L Glajch (N. Billerica. MA) G. A. Guiochon (Knoxville. TN) P R. Haddad (Kensington. N.S.w.) I. M. Hais (Hradec Kralove) W. S. Hancock (San Francisco. CAl S. Hjerten (Uppsala) Cs. Horvath (New Haven. CT) J. F. K. Huber (Vienna) K.-P. Hupe (Waldbronn) T. W. Hutchens (Houston. TX) J. Janak (Brno) P. Jandera (Pardubice) B. L Karger (Boston. MA) E. 5Z. Kovats (Lausanne) A. J. P, Martin (Cambridge) L. W. McLaughlin (Chestnut Hill, MA) J. D. Pearson (Kalamazoo. MI) H. Poppe (Amsterdam) F. E. Regnier (West Lafayene. IN) P. G. Righetti (Milan) P. Schoenmakers (Eindhoven) G. Schomburg (Mulheim/Ruhr) R. Schwarzenbach (Dubendorf) Fl. E. Shoup (West Lafayette. IN) ..... M. SiOL,ffi (Marseille) D. J. Strydom (Boston. MA) K. K. Unge, (Mainz) Gy. Vigh (College Station. TX) J. T. Watson (East Lansing. MI) B. D. Westerlund (Uppsala) : " _I ~ 1 ·f.1 -f I EDjTORS, £3iBlIOGRAPHY SECTION z. Deyl (Prague). o. Ja,,2k (llrno). V. Schwarz (Prague). K. Macek (Prague) ELSEVIER JOURNAL OF CHROMATOGRAPHY Scope. The Journal of Chromatography publishes papers on all aspects of chromatography. electrophoresis and related methods. Contributions consist mainly of research papers dealing with chromatographic theo­ ry, instrumental development and their applications. The section Biomedical Applications, which is under separate editorship, deals with the following aspects: developments in and applications of chromatogra­ phic and electrophoretic techniques related to clinical diagnosis or alterations during medical treatment; screening and profiling of body fluids or tissues with special reference to metabolic disorders; results from basic medical research with direct consequences in clinical practice; drug level monitoring and pharmaco­ kinetic studies; clinical toxicology; analytical studies in occupational medicine. Submission of Papers. Papers in English, French and German may be submitted, in three copies. Manu­ scripts should be submitted to: The Editor of Journal of Chromatography, P.O. Box 681, 1000 AR Am­ sterdam, The Netherlands, or to: The Editor of Journal of Chromatography, Biomedical Applications, P.O. Box 681, 1000 AR Amsterdam. The Netherlands. Review articles are invited or proposed by letter to the Editors. An outline of the proposed review should first be forwarded to the Editors for preliminary dis­ cussion prior to preparation. Submission of an article is understood to imply that the article is original and unpublished and is not being considered for publication elsewhere. For copyright regulations, see below. Subscription Orders. Subscription orders should be sent to: Elsevier Science Publishers B.v.. P.O. Box 211,1000 AE Amsterdam, The Netherlands, Tel. 5803911, Telex 18582 ESPA NL. The Journal of Chro­ matography and the Biomedical Applications section can be subscribed to separately. Publication. The Journal of Chromatography (incl. Biomedical Applications) has 37 volumes in 1990. The subscription prices for 1990 are: J. Chromatogr. + Biomed. Appl. (Vols. 451-500): Dfl. 6734.00 plus Dfl. 1036.00 (p.p.h.) (total ca. USS 3885.00) J. Chromatogr. only (Vols. 451-500): Dfl. 5616.00 plus Dfl. 756.00 (p.p.h.) (total ca. USS 3186.00) Biomed. Appl. only (Vols. 525-534): Dfl. 2080.00 plus Dfl. 280.00 (p.p.h.) (total ca. USS 1180.00) Our p.p.h. (postage, package and handling) charge includes surface delivery of all issues, except to sub­ scribers in Argentina, Australia. Brasil, Canada. China, Hong Kong, India, Israel. Malaysia. Mexico, New Zealand. Pakistan, Singapore. South Africa. South Korea. Taiwan, Thailand and the U.S.A. who receive all issues by air delivery (S.A.L. - Surface Air Lifted) at no extra cost. For Japan, air delivery requires 50% additional charge; for all other countries airmail and S.A.L. charges are available upon request. Back vol­ umes of the Journal of Chromatography (Vols. 1-497) are available at Dfl. 195.00 (plus postage). Claims for missing issues will be honoured, free of charge, within three months after publication of the issue. Customers in the U.S.A. and Canada wishing information on this and other Elsevier journals, please contact Journal Information Center, Elsevier Science Publishing Co. Inc., 655 Avenue of the Americas, New York, NY 10010. Tel. (212) 633-3750. Abstracts/Contents Lists published in Analytical Abstracts, ASCA, Biochemical Abstracts, Biological Abstracts, Chemical Abstracts, Chemical Titles, Chromatography Abstracts, Clinical Chemistry Lookout, Current Contents/Physical. Chemical & Earth Sciences, Current Contents/Life Sciences, Deep-Sea Re­ search/Part B: Oceanographic Literature Review, Excerpta Medica, Index Medicus, Mass Spectrometry Bulletin. PASCAL-CN RS, Pharmaceutical Abstracts. Referativnyi Zhurnal. Science Citation Index and Trends in Biotechnology. See inside back cover for Publication Schedule, Information for Authors and information on Advertise­ ments. --------- ------------- -- © ELSEVIER SCIENCE PUBLISHERS BV - 1990 0021 -9673/90/$350 All rights reserved. No parI of this publication may be reproduced. stored in n retrieval system or transmitted in any form or by any means, electronic. mechanical. photocopying, recording or otherwise. without the prior written permiSSIon of the publisher. Elsevier Science Publishers BV. P.O. Box 330. 1000 AH Amsterdam. The Netherlands. Upon acceptance of an article by the journal. the author(s) will be asked to transfer copyright of the article to the publisher. The transfer will ensure the Widest possible dIssemination of information. Submission of an article for publication entails the authors' irrevocable and exclusive authorization of Ihe publisher to collect any sums or considerations for copying or reproduction payable by third parties (as mentioned in article 17 paragraph 2 of the Dutch Copyright Act of 1912 and the Royal Decree of June 20, 1974 (S. 351) pursuant to article 16 b of the Dutch Copyright Act of 1912) and/or to act in or out of Court in connection therewith. Special regulations for readers in the U.S.A. This journal has been registered with the Copyright Clearance Center, Inc. Consent is given for copying of articles for personal or internal use. or for the personal use of specific dients. This consent is given on the condition that the copier pays through the Center the per·copy fee stated in the code on the first page of each article for copying beyond that permilled by Sections 107 or 108 of the U.S. Copyright Law. The appropriate fee should be forwarded with a copy of the first page of the article to the Copyright Clearance Center. Inc., 27 Congress Street. Salem. MA 01970. U.S.A. If no code appears in al~ article. the author has not given broad consent to copy and permission to copy must be obtained directly from the author. All articles published prior to 1980 may be copied for a per-copy fee of USs 2.25, also payable through the Center. This consent does not extend to other kinds of copying. sllch as for general distribution. resale. advertising ann promotion purposes, or for creating new collective works. SpeCial written permission must be Obtained from the publisher for such copying. No responsibility is assumed by the Publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods. products, instructions or ideas contained in the materials herein. Because of rapid advances in the medical sciences, the Publisher recommends that independe,lt vcri~jc&tior, uf diagr.oses ap,d drug dosages should be made. Although all advertising material is expected to conform tf) ethir.al ~1T'~dical) Mar.~lar~s. :,lclusi.J'l it 1 th.s publication does not constitute a guarantee or endorsement of the quality m value 0'- sur.h produr:t ().,. C'f the Claims mal"1t' of :., by its :nanufacturer. This issue is printed on .acid-ffee paper. Printed in The Netherlands VOL. 524, NO.3 JOURNAL OF CHROMATOGRAPHY JUNE 13, 1990 CONTENTS Bibliography Section Liquid Column Chromatography B325 Gas Chromatography . B403 Planar Chromatography 8435 Electrophoresis .... 8458 ----:":'. <'~ ." ;1' 11"1i'iJU . 'l'111 j ..... 7 f\I~'0",;:3I. :7.. ~ Selective Sample Handling and Detection in High-Performance Liquid Chromatography Journal of Chromatography Library, 39 ::::::::::}}}}':parf::::~:::'??????:}':}:?::::':':??:} }}::':::::::??:::???}}}:::':::::}}:?i}}}}}'::?:}}}}}}}:::::::}:,::':://}}:,:,://?:::::'::????}}:???}:?/???i edited by R.W. Freit, Free University, Amsterdam, Contents: 1. On-line sample handling and The Netherlands, and K. Zecb, Byk Gulden trace enric~~t in liquid c~matograph~. Pharmaceuticals, Konstanz, FRG The determmwon of org~c.compounds m . water samples. 2. Determmwon of drugs Part A of thIS two-volume project attempts to treat the and their metabolites in biological samples sample handling and detection processes in a liquid chroma- by fully automated HPLC with on-line tographic system in an integrated fashion. The need for more solid-liquid extraction and pre-column selective and sensitive chromatographic methods to help switching. 3. Immobilization of compounds solve the numerous trace analysis problems in complex ~or ~lective interaction with ~alytes in samples is undisputed. However, few workers realize the liqU!d chro"!'atography..4. DesIgn and strong interdependence of the various steps _sample hand- <:ho~ce of swtable labelling reager!:ts for ling, separation and detection - which must be considered if hquld.chromatograp~~.5.. Ph~todlode array .. al I' B' Irod' detecuon and recogmuon mhigh- one wants to arrIve at an .0l;>um so utiOn.
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