DOCSLIB.ORG

Cphi & P-MEC China Exhibition List展商名单version版本20180116

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Cphi & P-MEC China Exhibition List展商名单version版本20180116 CPhI & P-MEC China Exhibition List展商名单 Version版本 20180116 Booth/ Company Name/公司中英文名 Product/产品 展位号 Carbosynth Ltd E1A01 Toronto Research Chemicals Inc E1A08 SiliCycle Inc. E1A10 SA TOURNAIRE E1A11 Indena SpA E1A17 Trifarma E1A21 LLC Velpharma E1A25 Anuh Pharma E1A31 Chemclone Industries E1A51 Hetero Labs Limited E1B09 Concord Biotech Limited E1B10 ScinoPharm Taiwan Ltd E1B11 Dongkook Pharmaceutical Co., Ltd. E1B19 Shenzhen Salubris Pharmaceuticals Co., Ltd E1B22 GfM mbH E1B25 Leawell International Ltd E1B28 DCS Pharma AG E1B31 Agno Pharma E1B32 Newchem Spa E1B35 APEX HEALTHCARE LIMITED E1B51 AMRI E1C21 Aarti Drugs Limited E1C25 Espee Group Innovators E1C31 Ruland Chemical Co., Ltd. E1C32 Merck Chemicals (Shanghai) Co., Ltd. E1C51 Mediking Pharmaceutical Group Ltd E1C57 珠海联邦制药股份有限公司/The United E1D01 Laboratories International Holdings Ltd. FMC Corporation E1D02 Kingchem (Liaoning) Chemical Co., Ltd E1D10 Doosan Corporation E1D22 Sunasia Co., Ltd. E1D25 Bolon Pharmachem Co., Ltd. E1D26 Savior Lifetec Corporation E1D27 Alchem International Pvt Ltd E1D31 Polish Investment and Trade Agency E1D57 Fischer Chemicals AG E1E01 NGL Fine Chem Limited E1E24 常州艾柯轧辊有限公司/ECCO Roller E1E25 Linnea SA E1E26 Everlight Chemical Industrial Corporation E1E27 HARMAN FINOCHEM E1E28 Zhechem Co Ltd E1F01 Midas Pharma GmbH Shanghai Representativ E1F03 Supriya Lifescience Ltd E1F10 KOA Shoji Co Ltd E1F22 NOF Corporation E1F24 上海贺利氏工业技术材料有限公司/Heraeus E1F26 Materials Technology Shanghai Ltd. Novacyl Asia Pacific Ltd E1F28 PharmSol Europe Limited E1F32 Bachem AG E1F35 Louston International Inc. E1F51 High Science Co Ltd E1F55 Chemsphere Technology Inc. E1F57a PharmaCore Biotech Co., Ltd. E1F57b Rockwood Lithium GmbH E1G51 Sarv Bio Labs Pvt Ltd E1G57 抗病毒类、抗肿瘤类、抗感染类和甾体类中间体、原料药和药物制剂及医药合约研发和加工服务 上海创诺医药集团有限公司/Shanghai Desano APIs and Finished products of ARV, Oncology, Anti-infection and Hormone drugs and E1H01 Pharmaceuticals Co., Ltd. pharmaceutical CRO & CDMO service APIs and Finished products of ARV, Oncology, Anti-infection and Hormone drugs and pharmaceutical CRO & CDMO service 培他米松、地塞米松、泼尼松、泼尼松龙、甲泼尼龙、醋酸氢化可的松、螺内酯、氨基酸、GCLE 、7AVCA、头孢地尼、核黄素磷酸钠、甲睾酮、阿替洛尔、尼莫地平、阿加曲班、尼美舒利、阿 德福韦酯、注射用氢化可的松、注射用马来酸阿奇霉素、肝素钠注射液、注射用尿激酶、黄芪皂苷 天津市医药集团有限公司/Tianjin Tianfa I、II、III、番泻叶提取物、甜菊糖苷、萝卜硫素。Betamethasone Base, Dexamethasone Base, E1H16 Pharmaceuticals Imp. & Exp. Corp. Prednisone, Prednisolone, Methylprednisolone, Hydrocortisone Acetate, Spironolactone, Amino Acid, Budesonide, Fluocinolone Acetonide, Fluocinonide, Triamcinolone Base, Triamcinolone Acetonide, Halcinonide, Hydrocortisone Butyrate, GCLE, Cefidinir, 头孢克肟,头孢地尼,氧氟沙星,左氧氟沙星,盐酸环丙沙星,盐酸克林霉素,拉索拉唑,奥美沙坦,替米沙Biboflavin-5-Phosphate Sodium, Methyltestosterone, Atenolol, Nimodipine, Argatroban, 坦,UDCA,尼扎替丁,伊贝沙坦, 氟比洛芬, 洛索洛芬钠, 美索巴莫, 瑞巴派特, 盐酸金刚烷胺, 盐酸安非 他酮, 盐酸多奈哌齐, 加巴贲丁, 氟苯尼考, 碘海醇, 氯霉素, 中间体, 化工品Cefixime, Cefdinir, 浙江横店普洛进出口有限公司/Zhejiang Hengdian Ofloxacin, Levofloxacin, Ciprofloxacin HCl, Clindamycin Hydrochloride, Lansoprazole, E1H20 Apeloa Imp. &Exp. Co., Ltd. Olmesartan, Telmisartan, UDCA, Nizatidine, Irbesartan, Flurbiprofen, Loxoprofen sodium, Methocarbamol, Rebamipide, Amantadine Hydrochloride, Bupropion Hydrochloride, Donepezil Hydrochloride, Gabapentin, Florfenicol, Iohexol, Chloramphenicol, Intermediates, Chemicals.Cefixime, Cefdinir, Ofloxacin, Levofloxacin, Ciprofloxacin HCl, 赛诺菲（中国）投资有限公司上海分公司 E1H22 /Sanofi(China)Investment Co., Ltd. Shanghai 安徽贝克联合制药有限公司/Anhui Biochem United E1H28 拉米夫定0 Pharmaceutical Co.,Ltd. Medieye Holding Co., Limited E1H29 Chiral Quest (Suzhou) Co., Ltd E1H32 Chunghwa Chemical Synthesis & Biotech Co., E1H37a Ltd. Chirogate International Inc. E1H37b Amano Enzyme China Ltd E1H38 Granules India Ltd E1H57 APC Pharmaceutical & Chemical Ltd E1J37 SCI Pharmtech, Inc E1J38 Morepen Laboratories Ltd E1J55 盐酸克林霉素,盐酸克林霉素棕榈酸酯,克林霉素磷酸酯Clindamycin HCl,Clindamycin Palmitate 浙江海翔药业销售有限公司/Zhejiang Hisoar E1K01 HCl,Clindamycin PhosphateClindamycin HCl,Clindamycin Palmitate HCl,Clindamycin Pharmaceutical sales Co.,Ltd. Phosphate 苯磺阿曲库铵,酒石酸布托啡诺,卡培他滨,醋酸卡泊芬净,塞来昔布,苯磺顺阿曲库铵,硫酸氢氯吡格雷, 达托霉素,地氟烷,盐酸右美托咪定,三水多西他赛,碘化油,依托泊苷,钆特酸葡胺,异环磷酰胺,碘克沙 醇,碘佛醇,盐酸伊立替康,盐酸氯胺酮,来曲唑,美司钠,奥美沙坦,奥沙利铂,七氟烷,替加氟,替莫唑胺,托 江苏恒瑞医药股份有限公司/Jiangsu Hengrui 伐普坦,卡莫司汀,度他雄胺,钆布醇,碘海醇,注射用醋酸卡泊芬净,注射用苯磺顺阿曲库铵,吸入用地氟 E1K08 Medicine Co., Ltd. 烷,多西他赛注射液,方达帕鲁注射液,加巴喷丁胶囊,盐酸伊立替康注射液,来曲唑片,奥沙利铂注射液, 注射用奥沙利铂,吸入用七氟烷,盐酸右美托咪定注射液,盐酸托伐普坦片,注射用塞替派,甲磺酸阿帕 替尼片,碘化油注射液,培门冬酶注射液,替吉奥胶囊,注射用替莫唑胺,注射用唑来膦酸,卡培他滨片,注 射用达托霉素,碘克沙醇注射液,碘海醇注射液,碘佛醇注射液Atracurium Besylate,Butorphanol 维生素E,生物素,辅酶Q10, 盐酸万古霉素,替考拉宁,米格列醇, 达托霉素, 替加环素Vitamin E,D- 浙江医药股份有限公司/Zhejiang Medicine Co., Ltd. E1K12 Biotin, CoQ10, Vancomycin HCl, Teicoplanin, Miglitol, Daptomycin, TigecyclineVitamin E,D- Biotin, CoQ10, Vancomycin HCl, Teicoplanin, Miglitol, Daptomycin, Tigecycline 更昔洛韦钠针剂,阿奇霉素针剂,左乙拉西坦针剂,依替巴肽针剂,泮托拉唑钠针剂,万古霉素针剂,伏立 康唑针剂,特利加压素针剂,阿昔洛韦针剂,硝普钠针剂,比伐卢定针剂,达托霉素针剂,塞替派针剂,林可 霉素针剂,阿奇霉素干混,地氯雷他定片/干混,双膜嘧啶片Ganciclovir Sodium for Injection 海南普利制药股份有限公司/Hainan Poly Pharm ,Azithromycin for Injection ,Levetiracetam Injection ,Pantoprazole Sodium for Injection E1K16 Co., Ltd ,Eptifibatide Injection ,Vancomycin for Injection,Voriconazole for Injection,Terlipressin Injection,Acyclovir Injection,Sodium Nitroprusside for Injection,Bivalirudin for Injection,Daptomycin for Injection,Esomeprazole Sodium for Injection,Doxycycline for 克拉维酸钾二氧化硅Injection,Amiodarone 1:1 Hydrochloride克拉维酸钾微晶纤维素 Injection,Cyclophosphamide 1:1 阿莫西林克拉维酸钾 2:1for 阿莫西林克拉维酸钾Injection,Thiotepa 4:1 阿莫西林克拉维酸钾 7:1 阿莫西林钠克拉维酸钾 5:1 头孢氨苄 头孢羟氨苄 头孢噻肟钠 头孢唑林 钠 头孢替唑钠 头孢哌酮钠 头孢呋辛钠 头孢曲松钠 7-氨基头孢烷酸 去乙酰-7-ACA 头孢他啶二盐 国药集团威奇达药业有限公司/Sinopharm Weiqida 酸盐 7-APRA 头孢噻肟酸 Potassium Clavulanate with Syloid 1:1 Potassium Clavulanate with E1K18 Pharmaceutical Co.,Ltd. Avicel 1:1 Amoxicillin with Potassium Clavulanate 2:1 Amoxicillin with Potassium Clavulanate 4:1 Amoxicillin with Potassium Clavulanate 7:1 Amoxicillin Sodium with Potassium Clavulanate 5:1 Cefalexin Cefadroxil Cefotaxime Sodium Cefazolin Sodium Ceftezole Sodium Cefoperazone Sodium Cefuroxime Sodium Ceftriaxone sodium 7-ACA China Chinopharma Ltd. E1K20 --- 原料药：扑热息痛粉，扑热息痛颗粒，厄多司坦，高半胱氨酸硫内酯，橙皮甙，氨基葡萄糖硫酸 盐，葡萄糖酸盐，水飞蓟素等。制剂和片剂：聚明胶肽，法莫替丁，头孢泊肟酯，葡萄糖酸钙氯化 钠，葡萄糖氯化钠，苯磺酸氨氯地平片等。API: Paracetamol, Paracetamol DC, 浙江康乐药业股份有限公司/ZHEJIANG KANGLE Erdosteine,Homocysteine thiolactone, hesperidin,Glucosamine E1K26 PHARMACEUTICAL CO.,LTD. sulfate,gluconate,silymarin I etc..Preparation and tablets: Polygeline Injection, famotidine, Cefpodoxime Proxetil Tablets, Dextrose and Sodium Chloride Injection, Dextrose and Sodium Chloride Injection, Amlodipine besylate tablets, etc..API: Paracetamol, Paracetamol DC, Erdosteine,Homocysteine thiolactone, 东阳光/HEC E1K28 111 Lipoid AG E1K32 Alkaloids Corporation E1K35 江苏圣泰科合成化学有限公司/Synthetics China E1K51 CO.,LTD. VIRCHOW GROUP E1M32 F.I.S. Fabbrica Italiana Sintetici SpA E1M35 Angelini A.C.R.A.F SPA E1M36 Lusochimica S.P.A. E1M40 Chemcon Speciality Chemicals Private Limited E1M51 Dipharma Francis S.r.l E1M53 RCA KG E1M56 Indukern Hong Kong Limited E1M57 主营医药原料及其制剂,医药中间体及化学试剂、生化药品、中药材、中成药、生物制品、医药新 技术以及有关医药来料加工、补偿贸易、合作生产业务等。Chinese Medical herbs,Chinese 上海市医药保健品进出口有限公司/Shanghai Palent drugs,Health products,Pharmaceuticals and their preparations, pharmaceutical Medicines & Health Products Import & Export E1N01 intermediates,Chemical reagents,Biopreparations, Biochemical pharmaceuticals Co., Ltd. etc.Chinese Medical herbs,Chinese Palent drugs,Health products,Pharmaceuticals and their preparations, pharmaceutical intermediates,Chemical reagents,Biopreparations, Biochemical pharmaceuticals etc. 强力霉素,林可霉素,硫酸新霉素,维生素A,维生素B,维生素C,维生素D,三氯蔗糖,萘普生,克拉霉素,扑 热息痛,非那西汀Doxycycline Hcl,Lincomycin,Neomycin sulphate,Vitamin A,Vitamin 华中药业有限公司/Huazhong Pharmaceutical B,Vitamin C,Vitamin E1N10 Co., Ltd. D,Sucralose,Naproxen,Clarithromycin,Paracetamol,PhenacetinDoxycycline Hcl,Lincomycin,Neomycin sulphate,Vitamin A,Vitamin B,Vitamin C,Vitamin D,Sucralose,Naproxen,Clarithromycin,Paracetamol,Phenacetin 南方制药,多西他赛,10-DAB III,GMP证书,美国FDA认证.,紫杉醇,GMP药厂,盐酸苯达莫司汀,来曲唑, 伊马替尼south pharma,Docetaxel,10-DAB III,GMP certificate,USFDA 福建南方制药股份有限公司/Fujian South E1N12 inspection,Paclitaxel,GMP plant,Bendamustine HCl,Letrozole,IImatinib mesylatesouth Pharmaceutical Co., Ltd. pharma,Docetaxel,10-DAB III,GMP certificate,USFDA inspection,Paclitaxel,GMP plant,Bendamustine HCl,Letrozole,IImatinib mesylate 数据完整性保障FDA/EMA/CFDA的合规咨询（预审评估,偏差管理,整改计划与实现）工艺设备和 公用设施的确认实验室合规服务工程设计和支持第三方审计产品法规注册Data Intergrity Assurance---Computerized System ValidationFDA/EMA/CFDA Compliance Service (Mock 上海彼科意企业管理咨询有限公司/PQE Consulting Audit, Inspection Preparation, Gap management, Remediation Planing and E1N18 (Shanghai) Excuting)Process Equipment & Utilities QualificationLaboratory Compliance ServiceEngineering Design & ComplianceThird Party AuditRegulatory AffairsData Intergrity Assurance---Computerized System ValidationFDA/EMA/CFDA Compliance Service (Mock Audit, Inspection Preparation, Gap management, Remediation Planing and Panexcell Clinical Lab Private Limited E1N22 SUANFARMA Group E1N24 United States Pharmacopeia Standard R&D and E1N26 Technical Polpharma E1N28 Council of Euope - EDQM E1N32 Amarantine Pharmaceutical LLC E1N38 RAFICHEM E1N53 Shenzhen Haibin Pharmaceutical Co., Ltd. E1P01 丽珠医药集团股份有限公司/Livzon Pharmaceutical E1P01 Group Inc. Shin Nippon Yakugyo Co., Ltd E1P02 FMC Corporation E1P03 阿卡波糖、硫酸博莱霉素、环磷酰胺、阿糖胞苷、盐酸多柔比星、盐酸表柔比星、氟达拉滨磷酸酯 、盐酸吉西他滨、盐酸格拉司琼、伊维菌素、来曲唑、洛伐他汀、甲氨蝶呤、丝裂霉素、莫西克汀 、普伐他汀钠、吡喹酮、辛伐他汀、酒石酸长春瑞宾Acarbose、Bleomycin Sulfate、 浙江海正药业股份有限公司/Zhejiang Hisun Pharma. Cyclophosphamide、Cytarabine、Doxorubicin HCL、Epirubicin Hydrochloride、 E1P16 Co., Ltd. Fludarabine Phosphate、Gemcitabine Hydrochloride、Granisetron HCl、Ivermectin、 Letrozole、Lovastatin、Methotrexate、Mitomycin、Moxidectin、Pravastain
Load more

Recommended publications
  • The National Drugs List
    ^ ^ ^ ^ ^[ ^ The National Drugs List Of Syrian Arab Republic Sexth Edition 2006 ! " # "$ % &'() " # * +$, -. / & 0 /+12 3 4" 5 "$ . "$ 67"5,) 0 " /! !2 4? @ % 88 9 3: " # "$ ;+<=2 – G# H H2 I) – 6( – 65 : A B C "5 : , D )* . J!* HK"3 H"$ T ) 4 B K<) +$ LMA N O 3 4P<B &Q / RS ) H< C4VH /430 / 1988 V W* < C A GQ ") 4V / 1000 / C4VH /820 / 2001 V XX K<# C ,V /500 / 1992 V "!X V /946 / 2004 V Z < C V /914 / 2003 V ) < ] +$, [2 / ,) @# @ S%Q2 J"= [ &<\ @ +$ LMA 1 O \ . S X '( ^ & M_ `AB @ &' 3 4" + @ V= 4 )\ " : N " # "$ 6 ) G" 3Q + a C G /<"B d3: C K7 e , fM 4 Q b"$ " < $\ c"7: 5) G . HHH3Q J # Hg ' V"h 6< G* H5 !" # $%" & $' ,* ( )* + 2 ا اوا ادو +% 5 j 2 i1 6 B J' 6<X " 6"[ i2 "$ "< * i3 10 6 i4 11 6! ^ i5 13 6<X "!# * i6 15 7 G!, 6 - k 24"$d dl ?K V *4V h 63[46 ' i8 19 Adl 20 "( 2 i9 20 G Q) 6 i10 20 a 6 m[, 6 i11 21 ?K V $n i12 21 "% * i13 23 b+ 6 i14 23 oe C * i15 24 !, 2 6\ i16 25 C V pq * i17 26 ( S 6) 1, ++ &"r i19 3 +% 27 G 6 ""% i19 28 ^ Ks 2 i20 31 % Ks 2 i21 32 s * i22 35 " " * i23 37 "$ * i24 38 6" i25 39 V t h Gu* v!* 2 i26 39 ( 2 i27 40 B w< Ks 2 i28 40 d C &"r i29 42 "' 6 i30 42 " * i31 42 ":< * i32 5 ./ 0" -33 4 : ANAESTHETICS $ 1 2 -1 :GENERAL ANAESTHETICS AND OXYGEN 4 $1 2 2- ATRACURIUM BESYLATE DROPERIDOL ETHER FENTANYL HALOTHANE ISOFLURANE KETAMINE HCL NITROUS OXIDE OXYGEN PROPOFOL REMIFENTANIL SEVOFLURANE SUFENTANIL THIOPENTAL :LOCAL ANAESTHETICS !67$1 2 -5 AMYLEINE HCL=AMYLOCAINE ARTICAINE BENZOCAINE BUPIVACAINE CINCHOCAINE LIDOCAINE MEPIVACAINE OXETHAZAINE PRAMOXINE PRILOCAINE PREOPERATIVE MEDICATION & SEDATION FOR 9*: ;< " 2 -8 : : SHORT -TERM PROCEDURES ATROPINE DIAZEPAM INJ.
    [Show full text]
  • First Reversals of Cognitive Decline in Alzheimer's Disease and Its
    1/12/2017 First Reversals of Cognitive Decline in Alzheimer’sSystems Therapeutics, Disease and its PresidentPrecursors, Obama, MCI and and the End ofSCI Alzheimer’s Disease Dale E. Bredesen, M.D. Augustus Rose Professor Easton Laboratories for Neurodegenerative Disease Research UCLA Founding President, Buck Institute “There is nothing that will prevent, reverse, or slow the progress of Alzheimer’s disease.” “Everyone knows someone who is a cancer survivor; no one knows an Alzheimer’s survivor.” 1 1/12/2017 30,000,000 patients in 2012 3rd leading cause (James, B. D. et al. Contribution of Alzheimer disease to mortality in the United States. Neurology 82, 1045-1050, doi:10.1212/WNL. 0240 (2014) Pres. Obama and NAPA, 2011 160,000,000 patients in 2050 2 1/12/2017 Women at the epicenter of the epidemic •65% of patients •60% of caregivers •More common than breast cancer 0 Cures 3 1/12/2017 Alzheimer’s Disease (AD) Therapeutic Landscape A production APPROVED A aggregation Donepezil (Aricept) A clearance Rivastigmine (Exelon) Tau aggregation/phosph Galantamine (Razadyne) Cholinergic drugs Tacrine (Cognex) Others Memantine (Namenda) PHASE 3 PHASE 2 PHASE 1 Solanezumab ELND005 PBT2 AL-108 GSK933776 NIC5-15 PF04360365 AF102B MABT5102A Bapineuzmab Valproate Bryostatin-1 Nicotinamide Talsaclidine EHT-0202 NP12 ACC001 UB311 Alzemed Antioxidant BMS708163 Lithium AN1792 R1450 Begacestat Semagacestat Statins ABT089 NGF CAD106 V950 PF3084014 AZD3480 SB742457 Flurizan Dimebon E2012 Huperzine-A PRX03140 CTS21166 Rosiglitazone EGCg EVP6124 PUFA MK0752 MEM3454 TTP448 Phenserine CHF5074 PF-04447943 Clinical Trial in AD terminated “Game of Throwns” (243/244) R.I.P. R.I.P. R.I.P.
    [Show full text]
  • Estroquench™ Hormone Specific Formulation™
    PRODUCT DATA DOUGLAS LABORATORIES® 08/2014 1 EstroQuench™ Hormone Specific Formulation™ DESCRIPTION EstroQuench™ is a Hormone Specific Formulation™ of ingredients that have documented anti-aromatase activity as well as androgenic adaptogens which support the function of endogenous aromatase inhibitors. Collectively these herbs promote minimal production and function of estrogens, while promoting testosterone function, including optimal sexual function in both genders. This formulation is designed to quench excessive production of estrogens and aberrant functions of them while supporting optimal function of androgens by maintaining the health of androgen producing glands.† Hormone Specific Formulation™ provided by Douglas Laboratories® and formulated by Dr. Joseph J Collins is created to support the optimal function of specific hormones through the use of hormone specific adaptogens, hormone specific agonists and hormone specific functional mimetics. This formulation may be used as part of a hormone health program with dietary and nutrient support. In addition, this formulation may be used by clinicians as an adjuvant to support optimal hormone health in patients who have been prescribed bioidentical hormone therapies. FUNCTIONS Aromatase (a cytochrome P450 enzyme {CYP19}) is the enzyme that controls the conversion of androgens to estrogens. More specifically, aromatase is the enzyme responsible for catalyzing the biosynthesis of androstenedione into estrone, and the biosynthesis of testosterone to estradiol. Estrogens include the broad range of aromatized hormones created form androgens. The specific attribute of estrogens that separate them from progestogens, androgens and corticoids is that estrogens are the only aromatized steroid hormones. Estradiol, the most potent endogenous estrogen, is biosynthesized by aromatization from androgens by aromatase (which is also called estrogen synthase).
    [Show full text]
  • Supplementary Materials Evodiamine Inhibits Both Stem Cell and Non-Stem
    Supplementary materials Evodiamine inhibits both stem cell and non-stem-cell populations in human cancer cells by targeting heat shock protein 70 Seung Yeob Hyun, Huong Thuy Le, Hye-Young Min, Honglan Pei, Yijae Lim, Injae Song, Yen T. K. Nguyen, Suckchang Hong, Byung Woo Han, Ho-Young Lee - 1 - Table S1. Short tandem repeat (STR) DNA profiles for human cancer cell lines used in this study. MDA-MB-231 Marker H1299 H460 A549 HCT116 (MDA231) Amelogenin XX XY XY XX XX D8S1179 10, 13 12 13, 14 10, 14, 15 13 D21S11 32.2 30 29 29, 30 30, 33.2 D7S820 10 9, 12 8, 11 11, 12 8 CSF1PO 12 11, 12 10, 12 7, 10 12, 13 D3S1358 17 15, 18 16 12, 16, 17 16 TH01 6, 9.3 9.3 8, 9.3 8, 9 7, 9.3 D13S317 12 13 11 10, 12 13 D16S539 12, 13 9 11, 12 11, 13 12 D2S1338 23, 24 17, 25 24 16 21 D19S433 14 14 13 11, 12 11, 14 vWA 16, 18 17 14 17, 22 15 TPOX 8 8 8, 11 8, 9 8, 9 D18S51 16 13, 15 14, 17 15, 17 11, 16 D5S818 11 9, 10 11 10, 11 12 FGA 20 21, 23 23 18, 23 22, 23 - 2 - Table S2. Antibodies used in this study. Catalogue Target Vendor Clone Dilution ratio Application1) Number 1:1000 (WB) ADI-SPA- 1:50 (IHC) HSP70 Enzo C92F3A-5 WB, IHC, IF, IP 810-F 1:50 (IF) 1 :1000 (IP) ADI-SPA- HSP90 Enzo 9D2 1:1000 WB 840-F 1:1000 (WB) Oct4 Abcam ab19857 WB, IF 1:100 (IF) Nanog Cell Signaling 4903S D73G4 1:1000 WB Sox2 Abcam ab97959 1:1000 WB ADI-SRA- Hop Enzo DS14F5 1:1000 WB 1500-F HIF-1α BD 610958 54/HIF-1α 1:1000 WB pAkt (S473) Cell Signaling 4060S D9E 1:1000 WB Akt Cell Signaling 9272S 1:1000 WB pMEK Cell Signaling 9121S 1:1000 WB (S217/221) MEK Cell Signaling 9122S 1:1000
    [Show full text]
  • Test Report Comprehensive Hormone Insights™
    698814 COMPREHENSIVE HORMONE INSIGHTS™ TEST REPORT Dr. Maximus, N.D. E: [email protected] Date of Collection: P: 403-241-4500 Time of Collection: F: 403-241-4501 Date of Receipt: www.rmalab.com Reported On: CHI Accession: 698814 Healthcare Professional Patient Age: Dr. Maximus, N.D. Date of Birth: Gender: Male F: Relevant Medications Biometrics Curcumin Height (in) : 73 Weight (lb) : 180 BMI : 24 Waist (in) : 35 Hip (in) : 41 CHI Accession: 698814 SUMMARY HMUS01 How to read the graphs LEGEND: 50 66 Sex Steroid Hormones 50 66 Middle third of 33 33 84 reference population Hormone Start of 83 100 80 100 highest 16 Percentile Precursors 16 Percentile third of Sum of Androgens Sum of Estrogens 50 66 reference 0 0 population (T, DHT, α+β androstanediol) Listed in Interp Guide 33 84 End of 100 16 lowest Percentile00 50 66 50 66 third of 33 33 84 reference 0 population Patient’s percentile rank 81 100 95 100 compared to reference 16 Percentile 16 Percentile population (see summary) DHEA + Metabolites Sum of Progesterone Metabolites 0 (DHEA + A + E) 0 α+β Pregnanediol Cortisol Melatonin Oxidative Stress Free Cortisol Profile (ng/mg) 100 50 66 50 66 33 84 33 84 80 64 100 0 100 16 Percentile 16 Percentile 60 6-sulfatoxy 8-Hydroxy-2- 0 Melatonin 0 deoxyguanosine 40 (Overnight) (Overnight) 20 6-sulfatoxymelatonin provides 8-hydroxy-2-deoxyguanosine is Cortisol/Creatinine (ng/mg) insight into melatonin levels. a marker of oxidative stress 0 Morning Dinner Bedtime A B C 50 66 Free cortisol Cortisol Metabolites 33 84 profile is used to provides a general Testosterone Cortisol assess diurnal assessment of 16 100 cortisol rhythm adrenal cortisol 16 Percentile Cortisol production Cortisol Metabolites 0 (α+β THF + THE) Testosterone Cortisol/Testosterone provides insight into relative catabolic (cortisol) and anabolic (testosterone) states.
    [Show full text]
  • Mode of Action
    STROKE TBI DEMENTIA Mode of Action Reconnecting Neurons. Empowering for Life. NEW MULTI-MODAL THERAPIES FOR NEUROLOGICAL DISORDERS Sonic hedgehog (Shh) The Sonic Hedgehog (Shh) signalling pathway regulates the development Smoothened of organs including the organization of the brain. For example, the Shh (Smo) Patched (Ptch) activates the Gli complex, which is responsible for the expression of develop- mental genes underpinning neurorecovery and leading to an amplification of natural recovery. Gli Complex Gli Repressor Gli Activator Cerebrolysin activates the Shh pathway1 Cerebrolysin has a promoting effect on neurogenesis and oligodendrogenesis via stimulating the expression of the Shh signalling pathway. Cerebrolysin increases mRNA modulation of Shh and its receptors ‘Patched’ (Ptch) and ‘Smoothened’ (Smo). Shh PTCH Smo 5 * * 3 * 3 4 (n=9) (n=9) *p<0.05 (n=9) *p<0.05 *p<0.05 3 2 2 2 1 1 Fold changes (mean±SE) changes Fold (mean±SE) changes Fold 1 (mean±SE) changes Fold 0 0 0 0 20 0 20 0 20 CERE (µl/ml) CERE (µl/ml) CERE (µl/ml) Figure 1: Cerebrolysin stimulates the expression of the sonic hedgehog signalling pathway components in neural progenitor cells. Graphs show mRNA levels in an in vitro experiment. Studies confirm the important role of the sonic hedgehog pathway in post-stroke brain repair and functional recovery, and suggests the Shh pathway to be a possible target for prolongation of the therapeutic window after stroke.2 MAINTENANCE AND RECOVERY OF THE NEURONAL NETWORK Neurotrophic factors (NTFs) are signaling molecules that maintain, protect, and restore the neuronal network and ensure proper functioning of the brain.
    [Show full text]
  • 2018 Apigenin Male Infertility (2).Pdf
    Original Article Thai Journal of Pharmaceutical Sciences Apigenin and baicalin, each alone or in low-dose combination, attenuated chloroquine induced male infertility in adult rats Amira Akilah, Mohamed Balaha*, Mohamed-Nabeih Abd-El Rahman, Sabiha Hedya Department of Pharmacology, Faculty of Medicine, Tanta University, Postal No. 31527, El-Gish Street, Tanta, Egypt Corresponding Author: Department of Pharmacology, ABSTRACT Faculty of Medicine, Tanta University, Postal No. 31527, Introduction: Male infertility is a worldwide health problem, which accounts for about 50% of all El-Gish Street, Tanta, Egypt. cases of infertility and considered as the most common single defined cause of infertility. Recently, Tel.: +201284451952. E-mail: apigenin and baicalin exhibited a powerful antioxidant and antiapoptotic activities. Consequently, in [email protected]. the present study, we evaluated the possible protective effect of apigenin and baicalin, either alone or Edu.Eg (M. Balaha). in low-dose combination, on a rat model of male infertility, regarding for its effects on the hormonal assay, testicular weight, sperm parameters, oxidative-stress state, apoptosis, and histopathological Received: Mar 06, 2018 changes. Material and methods: 12-week-old adult male Wister rats received 10 mg/kg/d Accepted: May 08, 2018 chloroquine orally for 30 days to induce male infertility. Either apigenin (30 or 15 mg/kg/d), baicalin Published: July 10, 2018 (100 or 50 mg/kg/d) or a combination of 15 mg/kg/d apigenin and 50 mg/kg/d baicalin received daily
    [Show full text]
  • Mechanisms of Toxic Action of the Flavonoid Quercetin and Its Phase II Metabolites
    Mechanisms of toxic action of the flavonoid quercetin and its phase II metabolites Hester van der Woude Promotor: Prof. Dr. Ir. I.M.C.M. Rietjens Hoogleraar in de Toxicologie Wageningen Universiteit Co-promotor: Dr. G.M. Alink Universitair Hoofddocent, Sectie Toxicologie Wageningen Universiteit. Promotiecommissie: Prof. Dr. A. Bast Universiteit Maastricht Dr. Ir. P.C.H. Hollman RIKILT Instituut voor Voedselveiligheid, Wageningen Prof. Dr. Ir. F.J. Kok Wageningen Universiteit Prof. Dr. T. Walle Medical University of South Carolina, Charleston, SC, USA Dit onderzoek is uitgevoerd binnen de onderzoekschool VLAG Mechanisms of toxic action of the flavonoid quercetin and its phase II metabolites Hester van der Woude Proefschrift ter verkrijging van de graad van doctor op gezag van de rector magnificus van Wageningen Universiteit, Prof. Dr. M.J. Kropff, in het openbaar te verdedigen op vrijdag 7 april 2006 des namiddags te half twee in de Aula Title Mechanisms of toxic action of the flavonoid quercetin and its phase II metabolites Author Hester van der Woude Thesis Wageningen University, Wageningen, the Netherlands (2006) with abstract, with references, with summary in Dutch. ISBN 90-8504-349-2 Abstract During and after absorption in the intestine, quercetin is extensively metabolised by the phase II biotransformation system. Because the biological activity of flavonoids is dependent on the number and position of free hydroxyl groups, a first objective of this thesis was to investigate the consequences of phase II metabolism of quercetin for its biological activity. For this purpose, a set of analysis methods comprising HPLC-DAD, LC-MS and 1H NMR proved to be a useful tool in the identification of the phase II metabolite pattern of quercetin in various biological systems.
    [Show full text]
  • Note: the Letters 'F' and 'T' Following the Locators Refers to Figures and Tables
    Index Note: The letters ‘f’ and ‘t’ following the locators refers to figures and tables cited in the text. A Acyl-lipid desaturas, 455 AA, see Arachidonic acid (AA) Adenophostin A, 71, 72t aa, see Amino acid (aa) Adenosine 5-diphosphoribose, 65, 789 AACOCF3, see Arachidonyl trifluoromethyl Adlea, 651 ketone (AACOCF3) ADP, 4t, 10, 155, 597, 598f, 599, 602, 669, α1A-adrenoceptor antagonist prazosin, 711t, 814–815, 890 553 ADPKD, see Autosomal dominant polycystic aa 723–928 fragment, 19 kidney disease (ADPKD) aa 839–873 fragment, 17, 19 ADPKD-causing mutations Aβ, see Amyloid β-peptide (Aβ) PKD1 ABC protein, see ATP-binding cassette protein L4224P, 17 (ABC transporter) R4227X, 17 Abeele, F. V., 715 TRPP2 Abbott Laboratories, 645 E837X, 17 ACA, see N-(p-amylcinnamoyl)anthranilic R742X, 17 acid (ACA) R807X, 17 Acetaldehyde, 68t, 69 R872X, 17 Acetic acid-induced nociceptive response, ADPR, see ADP-ribose (ADPR) 50 ADP-ribose (ADPR), 99, 112–113, 113f, Acetylcholine-secreting sympathetic neuron, 380–382, 464, 534–536, 535f, 179 537f, 538, 711t, 712–713, Acetylsalicylic acid, 49t, 55 717, 770, 784, 789, 816–820, Acrolein, 67t, 69, 867, 971–972 885 Acrosome reaction, 125, 130, 301, 325, β-Adrenergic agonists, 740 578, 881–882, 885, 888–889, α2 Adrenoreceptor, 49t, 55, 188 891–895 Adult polycystic kidney disease (ADPKD), Actinopterigy, 223 1023 Activation gate, 485–486 Aframomum daniellii (aframodial), 46t, 52 Leu681, amino acid residue, 485–486 Aframomum melegueta (Melegueta pepper), Tyr671, ion pathway, 486 45t, 51, 70 Acute myeloid leukaemia and myelodysplastic Agelenopsis aperta (American funnel web syndrome (AML/MDS), 949 spider), 48t, 54 Acylated phloroglucinol hyperforin, 71 Agonist-dependent vasorelaxation, 378 Acylation, 96 Ahern, G.
    [Show full text]
  • Workbook Psychiatry and Narcology
    Kharkiv National Medical University Department of Psychiatry, Narcology and Medical Psychology WORKBOOK MANUAL FOR INDIVIDUAL WORK FOR MEDICAL STUDENTS PSYCHIATRY AND NARCOLOGY (Part 2) Student ___________________________________________________________ Faculty _________________________________________________________ Course _________________ Group _____________________________________ Kharkiv 2019 Затверджено вченою радою ХНМУ Протокол №5 від 23.05.2019 р. Psychiatry (Part 2) : workbook manual for individual work of students / I. Strelnikova, G. Samardacova, К. Zelenska – Kharkiv, 2019. – 103 p. Копіювання для розповсюдження в будь-якому вигляді частин або повністю можливо тільки з дозволу авторів навчального посібника. CLASS 7. NEUROTIC DISORDERS. CLINICAL FORMS. TREATMENT AND REHABILITATION. POSTTRAUMATIC STRESS DISORDER. TREATMENT AND REHABILITATION. Psychogenic diseases are a large and clinically varied group of diseases resulting from an effect of acute or long-term psychic traumas, which manifest themselves by both mental and somatoneurological disorders and, as a rule, are reversible. Psychogenic diseases are caused by a psychic trauma, i.e. some events which affect significant aspects of existence of the human being and result in deep psychological feelings. These may be subjectively significant events, i.e. those which are pathogenic for the majority of people. Besides, the psyche may be traumatized by conventionally pathogenic events, which cause feelings in an individual because of his peculiar hierarchy of values. Unfavorable psychogenic effects on the human being cause stress in him, i.e. a nonspecific reaction at the physiological, psychological and behavioural levels. Stress may exert some positive, mobilizing influence, but may result in disorganization of the organism activity. The stress, which exerts a negative influence and causes various disturbances and even diseases, is termed distress. Classification of neurotic disorders I.
    [Show full text]
  • Drug Name Plate Number Well Location % Inhibition, Screen Axitinib 1 1 20 Gefitinib (ZD1839) 1 2 70 Sorafenib Tosylate 1 3 21 Cr
    Drug Name Plate Number Well Location % Inhibition, Screen Axitinib 1 1 20 Gefitinib (ZD1839) 1 2 70 Sorafenib Tosylate 1 3 21 Crizotinib (PF-02341066) 1 4 55 Docetaxel 1 5 98 Anastrozole 1 6 25 Cladribine 1 7 23 Methotrexate 1 8 -187 Letrozole 1 9 65 Entecavir Hydrate 1 10 48 Roxadustat (FG-4592) 1 11 19 Imatinib Mesylate (STI571) 1 12 0 Sunitinib Malate 1 13 34 Vismodegib (GDC-0449) 1 14 64 Paclitaxel 1 15 89 Aprepitant 1 16 94 Decitabine 1 17 -79 Bendamustine HCl 1 18 19 Temozolomide 1 19 -111 Nepafenac 1 20 24 Nintedanib (BIBF 1120) 1 21 -43 Lapatinib (GW-572016) Ditosylate 1 22 88 Temsirolimus (CCI-779, NSC 683864) 1 23 96 Belinostat (PXD101) 1 24 46 Capecitabine 1 25 19 Bicalutamide 1 26 83 Dutasteride 1 27 68 Epirubicin HCl 1 28 -59 Tamoxifen 1 29 30 Rufinamide 1 30 96 Afatinib (BIBW2992) 1 31 -54 Lenalidomide (CC-5013) 1 32 19 Vorinostat (SAHA, MK0683) 1 33 38 Rucaparib (AG-014699,PF-01367338) phosphate1 34 14 Lenvatinib (E7080) 1 35 80 Fulvestrant 1 36 76 Melatonin 1 37 15 Etoposide 1 38 -69 Vincristine sulfate 1 39 61 Posaconazole 1 40 97 Bortezomib (PS-341) 1 41 71 Panobinostat (LBH589) 1 42 41 Entinostat (MS-275) 1 43 26 Cabozantinib (XL184, BMS-907351) 1 44 79 Valproic acid sodium salt (Sodium valproate) 1 45 7 Raltitrexed 1 46 39 Bisoprolol fumarate 1 47 -23 Raloxifene HCl 1 48 97 Agomelatine 1 49 35 Prasugrel 1 50 -24 Bosutinib (SKI-606) 1 51 85 Nilotinib (AMN-107) 1 52 99 Enzastaurin (LY317615) 1 53 -12 Everolimus (RAD001) 1 54 94 Regorafenib (BAY 73-4506) 1 55 24 Thalidomide 1 56 40 Tivozanib (AV-951) 1 57 86 Fludarabine
    [Show full text]
  • (Apigenin, Luteolin, Chrysin) and Their Importance for Health
    Mellifera 2020, 20(1):16-27 MELLIFERA REVIEW ARTICLE Flavones (Apigenin, Luteolin, Chrysin) and Their Importance for Health Fatma Özsel ÖZCAN1*, Ozan ALDEMİR2, Bülent KARABULUT3 1Beykoz Üniversity, Faculty of Art and Design, Department of Gastronomy and Culinary Arts, İstanbul, Turkey 2Ege University Faculty of Medicine, Department of Biochemistry, İzmir, TURKEY 3Ege University Faculty of Medicine, Department of Oncology, İzmir, TURKEY * Corresponding author e-mail: [email protected] Received: 14th March, 2020; accepted: 4th May, 2020; published: 29th June, 2020 A B S T R A C T It has been shown in recent years that foods called functional foods may protect against certain types of cancer, cardiovascular diseases and cognitive dysfunctions. In the studies performed, the flavonoids (apigenin, chrysin, luteolin) which are subclass of flavonoids have been shown to have antioxidant, antiinflammatory, antiallergic, neuroprotective and cardioprotective effects and it is presented as the current treatment method in the treatment of some diseases. The structure function, nutritional resources and potential therapeutic properties of the flavones, which are also used as supplement in the compost, have been studied. The purpose of this review is to evaluate the therapeutic effects of flavones in certain diseases. The positive effect of 16 flavones on health can be proven in many experimental studies and can be proven in the long run. Keywords: Functional nutrients, flavones, apigenin, luteolin, chrysin Introduction Polyphenolic flavonoids are among the affected by factors such as plant species, wide variety of phytochemicals found in the environment, genetics, light, maturity, human diet. Current studies reveal that harvest [3]. Flavones, a subset of dietary flavonoids are inversely related to flavonoids, form glycosylation and contain many cancers and age-related diseases [1].
    [Show full text]