Workbook Psychiatry and Narcology
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The National Drugs List
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LINKING INFECTIOUS and NARCOLOGY CARE) Evidence-Based for Engagement in HIV Care
COMPENDIUM OF EVIDENCE-BASED INTERVENTIONS AND BEST PRACTICES FOR HIV PREVENTION LINC (LINKING INFECTIOUS AND NARCOLOGY CARE) Evidence-Based for Engagement in HIV Care INTERVENTION DESCRIPTION Goal of Intervention • Improve engagement in HIV care • Improve retention in HIV care • Improve CD4+ cell count • Reduce self-reported hospitalizations Target Population • HIV-positive injecting drug users in treatment Brief Description LINC (Linking Infectious and Narcology Care) is an individual-level, strengths-based case management intervention for HIV-positive persons who inject drugs (PWID). It is adapted from the Antiretroviral Treatment Access Study (ARTAS). LINC involves coordination between the HIV and narcology systems of care to reduce barriers to HIV care and help motivate HIV-positive PWID to engage in care by supporting recognition of one’s strengths to make positive life changes. The initial session is delivered in a narcology hospital (e.g., in-patient addiction treatment setting) and includes provision of CD4 test results to increase engagement in HIV medical care. After discharge, subsequent sessions are conducted in community or clinic locations over six months. LINC aims to build self-efficacy, enable self-management, and increase outcome expectancies regarding engaging in HIV care via education and social support. Theoretical Basis • Social Cognitive Theory (SCT) • Psychological Empowerment Theory (PET) Intervention Duration • Five sessions delivered over six months Intervention Settings • Narcology hospital • Community or clinic locations • Phone Deliverer • Peer case managers (i.e., HIV-infected men and women in recovery from addiction) LRC Chapter – LINC (Linking Infectious and Narcology Care) Last updated March 17, 2020 COMPENDIUM OF EVIDENCE-BASED INTERVENTIONS AND BEST PRACTICES FOR HIV PREVENTION Delivery Methods • Case management • Printed materials • Discussion • Video • Goal setting Structural Components There are no reported structural components reported for this study. -
Autism Practice Parameters
American Academy of Child and Adolescent Psychiatry AACAP is pleased to offer Practice Parameters as soon as they are approved by the AACAP Council, but prior to their publication in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP). This article may be revised during the JAACAP copyediting, author query, and proof reading processes. Any final changes in the document will be made at the time of print publication and will be reflected in the final electronic version of the Practice Parameter. AACAP and JAACAP, and its respective employees, are not responsible or liable for the use of any such inaccurate or misleading data, opinion, or information contained in this iteration of this Practice Parameter. PRACTICE PARAMETER FOR THE ASSESSMENT AND TREATMENT OF CHILDREN AND ADOLESCENTS WITH AUTISM SPECTRUM DISORDER ABSTRACT Autism spectrum disorder (ASD) is characterized by patterns of delay and deviance in the development of social, communicative, and cognitive skills which arise in the first years of life. Although frequently associated with intellectual disability, this condition is distinctive in terms of its course, impact, and treatment. ASD has a wide range of syndrome expression and its management presents particular challenges for clinicians. Individuals with an ASD can present for clinical care at any point in development. The multiple developmental and behavioral problems associated with this condition necessitate multidisciplinary care, coordination of services, and advocacy for individuals and their families. Early, sustained intervention and the use of multiple treatment modalities are indicated. Key Words: autism, practice parameters, guidelines, developmental disorders, pervasive developmental disorders. ATTRIBUTION This parameter was developed by Fred Volkmar, M.D., Matthew Siegel, M.D., Marc Woodbury-Smith, M.D., Bryan King, M.D., James McCracken, M.D., Matthew State, M.D., Ph.D. -
Electro-Convulsive Therapy, History, and the Politics of Museum Display
A Tale of Two Objects: Electro-Convulsive Therapy, History, and the Politics of Museum Display James Bradley This essay offers a biography of two Electro-Convulsive Therapy (ECT) machines: the Bini-Cerletti machine used for the very first shock treatments and now housed in the History of Medicine Museum, Rome; and a machine from Adelaide based upon H.M. Birch’s original design and used to give the first shock treatments in Australia. In discussing these objects, I take a number of steps. Firstly, a short history of ECT introduces the major debates around the therapy and its history. Secondly, the machines are positioned within this history. Thirdly, the machines’ function within the galleries is discussed. Finally, I ask how these objects might be presented in a way that better reflects their history and the history of psychiatry more generally. Keywords: electro-convulsive therapy, material culture, museums and display, history of psychiatry, technology and innovation Objects and their Lives The subjects of this essay are two early Electro-Convulsive Therapy (ECT) machines that are now museum exhibits. In particular, it presents the machines as objects of material culture, revealing significant contours of the cultural domains of psychiatry and museums. It is, therefore, about the people to which these machines were connected, figuratively and literally, and the work that they did as therapeutic devices and now do as exhibits in museums. In effect, it presents a biography of the two objects. The first of the machines is the original. Designed and built by Ugo Cerletti’s team (notably Lucio Bini), it is now exhibited in the Museo di Storia della Medicina (History of Medicine Museum) at Sapienza, Rome. -
First Reversals of Cognitive Decline in Alzheimer's Disease and Its
1/12/2017 First Reversals of Cognitive Decline in Alzheimer’sSystems Therapeutics, Disease and its PresidentPrecursors, Obama, MCI and and the End ofSCI Alzheimer’s Disease Dale E. Bredesen, M.D. Augustus Rose Professor Easton Laboratories for Neurodegenerative Disease Research UCLA Founding President, Buck Institute “There is nothing that will prevent, reverse, or slow the progress of Alzheimer’s disease.” “Everyone knows someone who is a cancer survivor; no one knows an Alzheimer’s survivor.” 1 1/12/2017 30,000,000 patients in 2012 3rd leading cause (James, B. D. et al. Contribution of Alzheimer disease to mortality in the United States. Neurology 82, 1045-1050, doi:10.1212/WNL. 0240 (2014) Pres. Obama and NAPA, 2011 160,000,000 patients in 2050 2 1/12/2017 Women at the epicenter of the epidemic •65% of patients •60% of caregivers •More common than breast cancer 0 Cures 3 1/12/2017 Alzheimer’s Disease (AD) Therapeutic Landscape A production APPROVED A aggregation Donepezil (Aricept) A clearance Rivastigmine (Exelon) Tau aggregation/phosph Galantamine (Razadyne) Cholinergic drugs Tacrine (Cognex) Others Memantine (Namenda) PHASE 3 PHASE 2 PHASE 1 Solanezumab ELND005 PBT2 AL-108 GSK933776 NIC5-15 PF04360365 AF102B MABT5102A Bapineuzmab Valproate Bryostatin-1 Nicotinamide Talsaclidine EHT-0202 NP12 ACC001 UB311 Alzemed Antioxidant BMS708163 Lithium AN1792 R1450 Begacestat Semagacestat Statins ABT089 NGF CAD106 V950 PF3084014 AZD3480 SB742457 Flurizan Dimebon E2012 Huperzine-A PRX03140 CTS21166 Rosiglitazone EGCg EVP6124 PUFA MK0752 MEM3454 TTP448 Phenserine CHF5074 PF-04447943 Clinical Trial in AD terminated “Game of Throwns” (243/244) R.I.P. R.I.P. R.I.P. -
Boletin De Documentación Nº 37, Marzo De 2009
Su elaboración en formato electrónico, iniciada en julio de 2002, ha supuesto importantes ventajas de cara a ampliar y agilizar su difusión entre los profesionales del sector, permitiendo asimismo la localización de documentación relevante por parte de cualquier ciudadano interesado en el campo de las drogodependencias. Como en los números anteriores, en el boletín de marzo se recogen las principales novedades bibliográficas que, sobre los distintos aspectos relacionados con las adicciones, han tenido entrada en el Centro de Documentación e Información de la Delegación del Gobierno para el Plan Nacional sobre Drogas en los tres últimos meses. El contenido del Boletín está estructurado en tres grandes epígrafes: Novedades bibliográficas (clasificadas por su temática y con indicación de su ruta en el caso de que estén disponibles a texto completo en Internet), Legislación y Sumarios de revistas. Esperamos que el Boletín, cuya difusión se realiza a través de listas de distribución de correo electrónico y de su presencia permanente en la página web de la Delegación del Gobierno para el Plan Nacional sobre Drogas, sea de interés y quedamos a la espera de cualquier sugerencia y/o consulta que sobre el mismo queráis formular. Ministerio de Sanidad y Consumo. Delegación del Gobierno para el Plan Nacional sobre Drogas José del Val – E-correo: [email protected] Jefe de Servicio del Centro de Documentación e Información 1 Aspectos Generales ........................................................................ 4 Aspectos Sociales ............................................................................ -
Specificity of Psychosis, Mania and Major Depression in A
Molecular Psychiatry (2014) 19, 209–213 & 2014 Macmillan Publishers Limited All rights reserved 1359-4184/14 www.nature.com/mp ORIGINAL ARTICLE Specificity of psychosis, mania and major depression in a contemporary family study CL Vandeleur1, KR Merikangas2, M-PF Strippoli1, E Castelao1 and M Preisig1 There has been increasing attention to the subgroups of mood disorders and their boundaries with other mental disorders, particularly psychoses. The goals of the present paper were (1) to assess the familial aggregation and co-aggregation patterns of the full spectrum of mood disorders (that is, bipolar, schizoaffective (SAF), major depression) based on contemporary diagnostic criteria; and (2) to evaluate the familial specificity of the major subgroups of mood disorders, including psychotic, manic and major depressive episodes (MDEs). The sample included 293 patients with a lifetime diagnosis of SAF disorder, bipolar disorder and major depressive disorder (MDD), 110 orthopedic controls, and 1734 adult first-degree relatives. The diagnostic assignment was based on all available information, including direct diagnostic interviews, family history reports and medical records. Our findings revealed specificity of the familial aggregation of psychosis (odds ratio (OR) ¼ 2.9, confidence interval (CI): 1.1–7.7), mania (OR ¼ 6.4, CI: 2.2–18.7) and MDEs (OR ¼ 2.0, CI: 1.5–2.7) but not hypomania (OR ¼ 1.3, CI: 0.5–3.6). There was no evidence for cross-transmission of mania and MDEs (OR ¼ .7, CI:.5–1.1), psychosis and mania (OR ¼ 1.0, CI:.4–2.7) or psychosis and MDEs (OR ¼ 1.0, CI:.7–1.4). -
2021 Psychiatry CERT Content Specifications
CERTIFICATION EXAMINATION IN PSYCHIATRY Beginning in 2017, the American Board of Psychiatry and Neurology, Inc. (ABPN) issued two- dimensional content specifications for the psychiatry, neurology and child neurology certification examinations. Questions for the September 2021 psychiatry, neurology and child neurology certification examinations will conform to these content specifications. Within the two-dimensional format, one dimension is comprised of disorders and topics while the other is comprised of competencies and mechanisms that cut across the various disorders of the first dimension. By design, the two dimensions are interrelated and not independent of each other. All of the questions on the examination will fall into one of the disorders/topics and will be aligned with a competency/mechanism. For example, an item on substance use could focus on treatment, or it could focus on systems-based practice. The psychiatry, neurology and child neurology content specifications can be accessed from the specialty certification section of our website. Candidates should use the detailed content specifications as a guide to prepare for a certification examination. Scores for these examinations will be reported in a standardized format rather than the previous percent correct format. Starting in 2018, all future examinations given by the ABPN will gradually conform to the two- dimensional content specification. The American Board of Psychiatry and Neurology, Inc. is a not-for-profit corporation dedicated to serving the public interest and the professions of psychiatry and neurology by promoting excellence in practice through certification and continuing certification processes. For more information, please contact us at [email protected] or visit our website at www.abpn.com. -
Mode of Action
STROKE TBI DEMENTIA Mode of Action Reconnecting Neurons. Empowering for Life. NEW MULTI-MODAL THERAPIES FOR NEUROLOGICAL DISORDERS Sonic hedgehog (Shh) The Sonic Hedgehog (Shh) signalling pathway regulates the development Smoothened of organs including the organization of the brain. For example, the Shh (Smo) Patched (Ptch) activates the Gli complex, which is responsible for the expression of develop- mental genes underpinning neurorecovery and leading to an amplification of natural recovery. Gli Complex Gli Repressor Gli Activator Cerebrolysin activates the Shh pathway1 Cerebrolysin has a promoting effect on neurogenesis and oligodendrogenesis via stimulating the expression of the Shh signalling pathway. Cerebrolysin increases mRNA modulation of Shh and its receptors ‘Patched’ (Ptch) and ‘Smoothened’ (Smo). Shh PTCH Smo 5 * * 3 * 3 4 (n=9) (n=9) *p<0.05 (n=9) *p<0.05 *p<0.05 3 2 2 2 1 1 Fold changes (mean±SE) changes Fold (mean±SE) changes Fold 1 (mean±SE) changes Fold 0 0 0 0 20 0 20 0 20 CERE (µl/ml) CERE (µl/ml) CERE (µl/ml) Figure 1: Cerebrolysin stimulates the expression of the sonic hedgehog signalling pathway components in neural progenitor cells. Graphs show mRNA levels in an in vitro experiment. Studies confirm the important role of the sonic hedgehog pathway in post-stroke brain repair and functional recovery, and suggests the Shh pathway to be a possible target for prolongation of the therapeutic window after stroke.2 MAINTENANCE AND RECOVERY OF THE NEURONAL NETWORK Neurotrophic factors (NTFs) are signaling molecules that maintain, protect, and restore the neuronal network and ensure proper functioning of the brain. -
Comorbid Psychiatric Disorders in Children with Autism: Interview Development and Rates of Disorders
J Autism Dev Disord (2006) 36:849–861 DOI 10.1007/s10803-006-0123-0 ORIGINAL PAPER Comorbid Psychiatric Disorders in Children with Autism: Interview Development and Rates of Disorders Ovsanna T. Leyfer Æ Susan E. Folstein Æ Susan Bacalman Æ Naomi O. Davis Æ Elena Dinh Æ Jubel Morgan Æ Helen Tager-Flusberg Æ Janet E. Lainhart Published online: 15 July 2006 Ó Springer Science+Business Media, Inc. 2006 Abstract The Kiddie Schedule for Affective Disorders sample demonstrated a high prevalence of specific phobia, and Schizophrenia was modified for use in children and obsessive compulsive disorder, and ADHD. The rates of adolescents with autism by developing additional screening psychiatric disorder in autism are high and are associated questions and coding options that reflect the presentation of with functional impairment. psychiatric disorders in autism spectrum disorders. The modified instrument, the Autism Comorbidity Interview- Keywords Psychopathology Æ Autism Æ Psychiatric Present and Lifetime Version (ACI-PL), was piloted and interview Æ Comorbidity frequently diagnosed disorders, depression, ADHD, and OCD, were tested for reliability and validity. The ACI-PL provides reliable DSM diagnoses that are valid based on clinical psychiatric diagnosis and treatment history. The Children with autism frequently have problematic emo- tional reactions and behaviors along with the features that O. T. Leyfer Department of Psychological and Brain Sciences, University define autism. Disturbances of emotion, attention, activity, of Louisville, Louisville, KY, USA and thought, and associated behavioral problems occur in children with autism of all ages (Lainhart, 1999). It is not S. E. Folstein yet known how often these additional difficulties are due to Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA comorbid psychiatric disorders. -
Use of the Communication Checklist
Psychiatria Danubina, 2020; Vol. 32, Suppl. 1, pp 88-92 Conference paper © Medicinska naklada - Zagreb, Croatia USE OF THE COMMUNICATION CHECKLIST - SELF REPORT (CC-SR) IN SCHIZOPHRENIA: LANGUAGE IMPAIRMENTS CORRELATE WITH POOR PREMORBID SOCIAL ADJUSTMENT Daria Smirnova1,2, Svetlana Zhukova3, Olga Izmailova4, Ilya Fedotov5, Yurii Osadshiy6, Alexander Shustov7, Anna Spikina8, Dmitriy Ubeikon9, Anna Yashikhina2, Natalia Petrova10, Johanna Badcock1, Vera Morgan1 & Assen Jablensky1 1Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Australia 2Department of Psychiatry, Narcology, Psychotherapy and Clinical Psychology, Samara State Medical University, Samara, Russia 3Department of Psychiatry, Narcology and Psychology, Ivanovo State Medical Academy, Ivanovo, Russia 4Samara District Clinical Psychiatric Hospital, Samara, Russia 5Department of Psychiatry, Ryazan State Medical University n.a. academician I.P. Pavlov, Ryazan, Russia 6Department of Psychiatry, Narcology and Medical Psychology, Rostov State Medical University, Rostov-on-Don, Russia 7National Medical Research Centre of Psychiatry and Narcology n.a. V.P. Serbsky, Moscow, Russia 8Psychoneurological dispensary ʋ2, Saint Petersburg, Russia 9Department of Psychiatry, Narcology and Psychotherapy with the course of General and Medical psychology, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russia 10Department of Psychiatry and Narcology, Saint Petersburg State University, Saint Petersburg, -
Pharmacology on Your Palms CLASSIFICATION of the DRUGS
Pharmacology on your palms CLASSIFICATION OF THE DRUGS DRUGS FROM DRUGS AFFECTING THE ORGANS CHEMOTHERAPEUTIC DIFFERENT DRUGS AFFECTING THE NERVOUS SYSTEM AND TISSUES DRUGS PHARMACOLOGICAL GROUPS Drugs affecting peripheral Antitumor drugs Drugs affecting the cardiovascular Antimicrobial, antiviral, Drugs affecting the nervous system Antiallergic drugs system antiparasitic drugs central nervous system Drugs affecting the sensory Antidotes nerve endings Cardiac glycosides Antibiotics CNS DEPRESSANTS (AFFECTING THE Antihypertensive drugs Sulfonamides Analgesics (opioid, AFFERENT INNERVATION) Antianginal drugs Antituberculous drugs analgesics-antipyretics, Antiarrhythmic drugs Antihelminthic drugs NSAIDs) Local anaesthetics Antihyperlipidemic drugs Antifungal drugs Sedative and hypnotic Coating drugs Spasmolytics Antiviral drugs drugs Adsorbents Drugs affecting the excretory system Antimalarial drugs Tranquilizers Astringents Diuretics Antisyphilitic drugs Neuroleptics Expectorants Drugs affecting the hemopoietic system Antiseptics Anticonvulsants Irritant drugs Drugs affecting blood coagulation Disinfectants Antiparkinsonian drugs Drugs affecting peripheral Drugs affecting erythro- and leukopoiesis General anaesthetics neurotransmitter processes Drugs affecting the digestive system CNS STIMULANTS (AFFECTING THE Anorectic drugs Psychomotor stimulants EFFERENT PART OF THE Bitter stuffs. Drugs for replacement therapy Analeptics NERVOUS SYSTEM) Antiacid drugs Antidepressants Direct-acting-cholinomimetics Antiulcer drugs Nootropics (Cognitive