THIEME Review Article 167 Giovanni Alfonso Borelli: The Precursor of Medial Pivot Concept in Knee Biomechanics Nicola Piolanti1 Simone Polloni1 Enrico Bonicoli1 Michele Giuntoli1 Michelangelo Scaglione1 Pier Francesco Indelli2 1 Dipartimento di Ricerca Traslazionale e delle Nuove Tecnologie in Address for correspondence Nicola Piolanti, MD, Dipartimento di Medicina e Chirurgia, Università degli Studi di Pisa, Pisa, Italy Ricerca Traslazionale e delle Nuove Tecnologie in Medicina e 2 Department of Orthopaedic Surgery, Stanford University School of Chirurgia, Università degli Studi di Pisa, Via Paradisa 2, 56124 Pisa, Medicine, Stanford University, Stanford, California, United States Italy (e-mail:
[email protected]). Joints 2018;6:167–172. Abstract A new philosophy of science and medicine had spread throughout the 17th-century Italy: the “Scientific Revolution.” Giovanni Alfonso Borelli (1608–1679) was one of the most charismatic and brilliant scientists of his generation in Europe. He extended to biology the rigorous analytic methods developed by his indirect mentor Galileo in the field of mechanics. In his masterpiece “De Motu Animalium,” Borelli analyzed structure, Keywords motion, balance, and forces concerning almost all the principal joints of the human ► knee biomechanics body, in static and dynamic situations. In particular, he accurately studied the anatomy ► femoral rollback and biomechanics of the knee joint. He sustained that femoral condyles shift backward ► medial pivot during flexion, allowing a wider range of movement. Furthermore, he observed that, ► total knee when the knee flexes, the lateral condyle moves backward more than the medial arthroplasty condyle: this concept is nowadays known as medial pivoting. The aim of this article is to ► Giovanni Alfonso describe the life and work of this important Italian scientist and to present his Borelli unrecognized contribution to modern knee biomechanics.