Supplemental Table 2: Differentially-expressed genes in 3Y1-MUC1-CD cells grown as tumor xenografts that are functionally related to tumorigenesis, metastasis, cell motility, and angiogenesis. T = tumorigenesis; MCA = metastasis, cell motility, and angiogenesis.

Gene Symbol Description T MCA ABCC4 ATP-BINDING CASSETTE, SUB-FAMILY C (CFTR/MRP), MEMBER 4 * ACLY ATP-CITRATE LYASE * ACTB ACTIN, BETA * ADA ADENOSINE DEAMINASE * ADH1C ALCOHOL DEHYDROGENASE 1C * ANGPTL4 ANGIOPOIETIN-LIKE 4 * * APOC1 APOLIPOPROTEIN C-I * APOE APOLIPOPROTEIN E * * ASPH PEPTIDE-ASPARTATE BETA-DIOXYGENASE * AXIN2 AXIN 2 (CONDUCTIN, AXIL) * BAMBI BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR * BUB1B BUB1 BUDDING UNINHIBITED BY BENZIMIDAZOLES 1 HOMOLOG BETA (YEAST) * C5ORF13 CHROMOSOME 5 OPEN READING FRAME 13 * CA9 CARBONIC ANHYDRASE IX * CAPG CAPSULAR POLYSACCHARIDE SYNTHESIS ENZYME CAP5G * CASP1 CASPASE 1 * CASP4 CASPASE 4, APOPTOSIS-RELATED CYSTEINE PEPTIDASE * CAT CATALASE * CD248 CD248 ANTIGEN, ENDOSIALIN * CD59 CD59 ANTIGEN * * CD74 CD74 ANTIGEN * CDC20 CELL DIVISION CONTROL PROTEIN 20 * CDH2 CADHERIN 2, NEURONAL * * COL15A1 COLLAGEN, TYPE XV, ALPHA 1 * COL18A1 COLLAGEN TYPE XVIII, ALPHA 1 * * COL6A3 PROCOLLAGEN, TYPE VI, ALPHA 3 * COL6A3 COLLAGEN, TYPE VI, ALPHA 3 * CP CERULOPLASMIN (FERROXIDASE) * CST3 CYSTATIN C * * CTSC CATHEPSIN C * CTSH CATHEPSIN H * CTSS CATHEPSIN S * * DCN DECORIN * * DHCR24 24-DEHYDROCHOLESTEROL REDUCTASE * ECT2 EPITHELIAL CELL TRANSFORMING 2 * EGR1 EARLY GROWTH RESPONSE 1 * * F3 COAGULATION FACTOR III [THROMBOPLASTIN, TISSUE FACTOR] * * FASN FATTY ACID SYNTHASE * FGF13 FIBROBLAST GROWTH FACTOR 13 * FOS SIMILAR TO PROTO-ONCOGENE PROTEIN C-FOS * * GADD45A GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE, ALPHA * GPC1 GLYPICAN 1 * GSTM1 GLUTATHIONE S-TRANSFERASE M1 * HES1 HAIRY AND ENHANCER OF SPLIT 1, (DROSOPHILA) * * HLA-E MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, E * HRASLS3 HRAS LIKE SUPPRESSOR 3 * 1

HSD11B1 11-BETA HYDROXYSTEROID DEHYDROGENASE ISOFORM 1 * HSP90AB1 HEAT SHOCK PROTEIN 90-BETA * HTATIP2 HIV-1 TAT INTERACTIVE PROTEIN 2, 30KDA * * ID2 ID2 PROTEIN * * IDI1 ISOPENTENYL-DIPHOSPHATE DELTA ISOMERASE * IFITM1 INTERFERON INDUCED TRANSMEMBRANE PROTEIN 1 * IGFBP3 INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 * * IL2RG INTERLEUKIN 2 RECEPTOR, GAMMA * INSIG1 INSULIN INDUCED GENE 1 * ISG15 INTERFERON-STIMULATED PROTEIN, 15 KDA * ITGA1 INTEGRIN ALPHA 1 * * ITGB2 INTEGRIN, BETA 2 (COMPLEMENT COMPONENT 3 RECEPTOR 3 AND 4 SUBUNIT) * KIF20A KINESIN FAMILY MEMBER 20A * LAMA5 LAMININ, ALPHA 5 * * LAMC2 LAMIMIN, GAMMA 2 * LBP LIPOPOLYSACCHARIDE BINDING PROTEIN * MGP MATRIX GLA PROTEIN * MMP14 MATRIX METALLOPROTEINASE 14 * * MMP2 MATRIX METALLOPROTEINASE 2 * * MPHOSPH1 M-PHASE PHOSPHOPROTEIN 1 * MUC1 MUCIN 1, TRANSMEMBRANE * * MVD DIPHOSPHOMEVALONATE DECARBOXYLASE * PDLIM2 SIMILAR TO PDZ AND LIM DOMAIN 2 ISOFORM 2 * PLA2G2A PHOSPHOLIPASE A2, GROUP IIA (PLATELETS, SYNOVIAL FLUID) * POSTN PERIOSTIN, OSTEOBLAST SPECIFIC FACTOR * PPAP2B PHOSPHATIDIC ACID PHOSPHATASE TYPE 2B * PRKAR2B PROTEIN KINASE, CAMP-DEPENDENT, REGULATORY, TYPE II, BETA * PSAT1 PHOSPHOSERINE AMINOTRANSFERASE 1 * PTGS1 PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1 * PTGS2 PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2 * * PTN PLEIOTROPHIN * * QPCT GLUTAMINYL CYCLASE * RHOB RAS HOMOLOG GENE FAMILY, MEMBER B * * RRAS2 RELATED RAS VIRAL (R-RAS) ONCOGENE HOMOLOG 2 * RRM2 RIBONUCLEOTIDE REDUCTASE M2 POLYPEPTIDE * SCD STEAROYL-COA DESATURASE (DELTA-9-DESATURASE) * SDC1 SYNDECAN 1 * * SERPINE1 SERINE (OR CYSTEINE) PROTEINASE INHIBITOR, CLADE E, MEMBER 1 * * SLIT2 SLIT HOMOLOG 2 * * SPHK1 SPHINGOSINE KINASE 1 * * SQLE SQUALENE EPOXIDASE * SREBF1 STEROL REGULATORY ELEMENT BINDING TRANSCRIPTION FACTOR 1 * STAT1 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1, 91KDA * TFRC TRANSFERRIN RECEPTOR * TIAM1 T-CELL LYMPHOMA INVASION AND METASTASIS 1 * * TMEPAI SIMILAR TO TRANSMEMBRANE PROSTATE ANDROGEN-INDUCED PROTEIN ISOFORM B * TNN TENASCIN N * TPM1 TROPOMYOSIN * TUBB2A TUBULIN, BETA 2A * VCAM1 VASCULAR CELL ADHESION MOLECULE 1 * * VCAN CHONDROITIN SULFATE PROTEOGLYCAN 2 * XDH XANTHINE DEHYDROGENASE * XRCC5 X-RAY REPAIR COMPLEMENTING DEFECTIVE REPAIR IN CHINESE HAMSTER CELLS 5 *

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