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5456 Feder~llRegister I Vol. 47, No. 25 I Friday, February 5, 1982 I Notices " - mutual backup, but ~Isowill permit New Issued in Washington,D.C.on January 29, Ocean Quahog,FMP-published FR1-15-82: England utilities to reduce their 1982. this EIS has been granted a reduction of the dependence on oil and thereby to Bethel Lorey,1 review period which terminated on 1-26-82. achieve significant cost savings for their Acting Administrator. Economic Regulatory (EPA ElS #8200(9) customers. Administration. Correction: COE: Draft Supplement-I-70 Construction in Glenwood Canyon, Garfield The agreements between NEPOOL IFa Doc.82-3157 FlIed ~: S:458ml BIWNO CODE 8450-01-M County, Colorado-correction appearing In and Hydro-Quebec have not yet been FR 1-6-82 should not have been published- finalized. However, contract refer to original publication in FR 12-31-81. negotiations are currently under way, ENVIRONMENTAL PROTECTION (EPA IDS #811032) Extended Reviews: DOC: NOAA: Draft- and it is expected that contracts will be AGENCY executed in the near future. Coral and Coral Reefs FMP. Gulf of Mexico The applicant proposes to construct [ER-FRL-2044-1] and South Atlantic-published FR 12-18-82: an international interconnection at the Due 3-1-62. (EPA IDS#810998) Availabilityof Environmental Impact COE: Draft-Wynoochee Hydropower/Fish U.S.-Canadian border near Norton, Statements Flied Hatchery Development, Grays Harbor Vermont. The international transmission County. Washington-published FR 12-11-81;. line will interconnect a new terminal to Responsible Agency: Office of Federal Activities, EPA. Due 2-26-82. (EPA ElS #810983) be located in the vicinity of Sherbrooke, DOT: Bureau of Reclamation: Draft- Information Contact: Ms.Kathi Wilson (202) Quebec, and a terminal to be located at 245-3006. Chikaslda Water Supply Project. Kansas and the Comerford Station in Monroe, New IDS's Filed: January 25-29,1982. Oklahoma-published FR 1G-9-81 Due 3-1- Hampshire, and constructed by NEET. Comment Due Dates: Drafts-March 22, 82. (EPA IDS #810817) " The Canadian portion of the fncilities 1982: Finals-March 8, 1982. Dated: February 2, 1982. will be built by Hydro-Quebec. Each of Corps of Engineers (COE): Draft-Bogue Paul C. Cahill, the terminals will, among othElrthings, InlelNavigation Improvements. Onslow and Carte'ret Counties. North Carolina. (EPA IDS Director. Office of Federal ActiviU'es. convert the power being transmitted #820038) . IFa Doc. sz..1148 FiJed z.+6Z;8:45 am) from alternating current (ac) to direct COE: Flnal-Crown Bay/Charlotte Amalie BIWNO CODE aseo-37-M current (de), and imported power from Port Facility, Permit, St. Thomas. Virgin dc to aCt Islands. (EPA IDS#8200(5) VELCO considered severalillternative DOl: Office of Surface Mining: Final- [OPTS 41008; TSH-FRL-2Q43-3J Antelope Mining and Reclamation Plan, corridors before choosing the preferred Approval, Converse County, Wyoming. (EPA route which runs from the border . Ninth Report of the Interagency IDS #820(37) Testing Committee to the crossing at Norton, Vermont to Monroe, DOT: Federal Highway Administration New Hampshire. According to the (FHWA): Draft-FH-61 Reconstruction, MT- Administrator; Receipt of Report and 40 to Rt. 8, Flathead National Forest, Flathead Request for Comments Regarding applicant, "the preferred corridor has Priority Ust of Chemicals been found superior to the alternatives County. Montana; Extended Review 3-31-82. (EPA IDS #820(35) because it avoids major settlement AGENCY:Environmental Protection DOT: FHWA: Final-A-C Couplet. A areas and all major environmentally Street South from Sixth. Anchorage. Alaska. Agency (EPA). sensitive areas, and minimizeu the (EPA IDS #8200(3) ACTION: Notice. disruption to the aesthetic integrity of EPA: Region 4: Flnal-South Fort M~ade the northeast region of VermOl1L" Phosphate Mine. NPDES Permit, Polk County, SUMMARY:The Jnteragency Testing Any person desiring to be heard or to Florida. (EPA IDS#820(44) Committee (ITC),established under Department of Housing and Urban protest said application should file a Development (HUD): Draft-Desert Falls section 4(e) of the Toxic Substances petition to intervene or protest with the Country Club. Mortgage Insurance. Riverside Control Act (TSCA).transmitted its Office of Emergency Operations, County. California. (EPA IDS #8200(2) Ninth Report to the Administrator of Department of Energy,RoomCH-034-G, HUD: Final-Crestview Estates EPAon October 30,1981.This report, Forrestal Building, Washington. D.C. Development, Mortgage Insurance, Campbell which revises and updates the 20585. in accordance with §§ 1.8 or 1.10 County, Wyoming. (EPA IDS#820036) CommiUee'spriority list of chemicals, USDA: Rural EIectrtflcation of the Rules of Practice and Procedure adds three chemicals to the list for Administration: Final-Antelope Valley to (18 CFR 1.8, 1.10). priority consideration by EPAin the Charlie Creek Transmission Line. Billings. promulgation of test rules under section Any such petitions and protests " Dunn, McKenzie and Mercer Counties, North 4(a) of the AcLIt also noted the removal should be filed on or before Murch 22, Dakota. (EPA IDS #820(39) of four entries from the list. The three 1982. Protests will be considerud by USDA: Conservation Service: Draft- Diamond Creek Watershed Flood Protection new chemicals are chlorendic acid, 4- DOE in determining the appropriate action to be taken, but will not serve to Plan, Chase and Morris Counties, Kansas. chlorobenzotrifluoride. and tris(2- (EPA IDS#8200(1) chIoroethyl)phosphite. The deletions make protestants parties to the Interstate Commerce Commission: Final from the list are dichloromethane, proceeding. Any person wishing to Supplement-Somerset Railroad nitrobenzene, t.t.l-trichloroethane and Construction and Operation, Niagara County, become a party must file a petition to . the category alkyl tin compounds. The intervene. Copies of this application are New York. (EPA IDS#820040) Waiver: DOC: National Oceanic and Ninth Report is included in this notice. on me with DOE and will, upon request, Atmospheric Administration (NOAA): Final The Agency invites interested persons be made available for public inspection Supplement-Mid-Atlantic Surf Clam and to submit written comments on the and copying at the DOE Docket Room, Report and to indicate if an informal Room lE-190, Forrestal Building. I In the recent reorganization of DOE. meeting would be useful in focusing"and Washington, D.C.. from 8 a.m. to 4 p.m., responsibility for Presidential Permits wa8 narrowing the issues raised by the ITc; Monday through Friday. transferred from ERA to the OlfIce of recommendations. . Environmental Protection. Safety, and Emergency DATE:Written comments should be Preparedness. DOE 18 In the proces8 of redelesat1ng authority. submitted by March 8, 1982.

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ADDRESSES:Send written submissions proposed test rules for these substances Office who will inform them of all such to: Document Control Office (TS-793), on June 5.1981 (45 FR 30300).The meetings that are scheduled. Committee also has removed the Office of Pesticides and Toxic Dated: January 28,1982. Substances, Environmental Protection category "Alkytin Compounds" from the John A. Todhunter. Agency. Rm. E-401. 401 M St.. list and will reconsider the need for futher testing of ,uch compounds and Assistant Administrator for Pesticides and Washington, D.C. 20480. ToxicSubstances. Submissions should bear the their appropriate categorization. Document Control Number OPTS-41008. Readers of the ITC Ninth Report also Ninth Report of the TSCA Interagency The public record supporting this action, should note that EPA recently has taken Testing Committee to The including comments. is available for action on the following eleven chemicals Administrator. Environmental Protection public inspection iIi Rm. E-107 at the and categories designated by the ITC. Agency addrttss noted above from 8:00 a.m. to fulfilling the Agency's obligation u.nder 4:00 p.rn. Monday through Friday. except TSCA section 4(e) with respect to those Summary legal holidays. designations: Alkyl phthalates and Section 4 of the Toxic Substances FOR FURTHER INFORMATION CONTACT: benzyl butyl phthalate (46FR 53775). Control Act of 1976 (TSCA, Pub. L. 94- Douglas G. Bannerman, Acting Director. butyl glycolyl butyl phthalate (46 FR 489) provides for the testing of 64487), chlorinated naphthalenes (46 FR Industry Assistance Office (TS-799). chemicals in commerce that may present 54451).Ouoroalkenes(46FR53704), Office of Toxic Substances. an unreasonable risk of injury to health Environmental Protection Agency. 401 M polychlorinated terphenyls (46 FR or the environment. It also provides for Street. SW.. Washington, D.C. 20460. 54482). benzidine-based dyes. 0- the establishment of a Committee. dianisidine-based dyes, and o-tolidine- Toll Free: 800-424-9065. In Washington. composed of representatives from eight based dyes (46 FR 55004).chlorinated D.C.: 554-1404. Outside the USA: designated Federal agencies, to (Operato1'-202-554-1404). paraffins (47 FR 1017) and recommend chemical substances or SUPPLEMENTARY INFORMATION: phenylenediamines (47 FR 973). mixtures to which the Administrator of DI. Public Comments the U.S. Environmental Protection J. Background Agency (EPA) should give priority EPA invites interested persons to See. 4(a) of1'SCA authorizes the consideration for the promulgation of Administrator ofEPA to promulgate submit written comments on the ITC's new recommendations. The Agency is testing rules. The Committee makes regulations requiring testing of chemical such revisions in the List (the section substances in order to develop data especially interested in receiving information concerning any additional 4(e) Priority List) as it determines to be relevant to determining the risks that necessary and transmits them to the or ongoing health and safety testing of such chemical substances may present . EPA Administrator at least every six to health and the environment. .the newly designated chemicals that months. may respond to the concerns expressed See. 4(e) ofTSCA established an . As a result of its deliberations. the Interagency Testing Committee to make by the ITC. The Agency requests that recommendations to the Administrator submissions be received no later than Committee is revising the TSCA section of EPA of chemical substances to be March 8. 1982. All submissions received 4(e) Priority List by the addition of three entries and the removal of four. The given priority consideration in proposing by that date will be' considered by the test rules under Sec. 4(a):Sec. 4(e) Agency in determining whether to chemicals being added to the list are directs the Committee to revise its list of propose test rules in response to the presented alphabetically, together with Committee's new recommendations. the types of testing recommended, as recommendations at least every six follows: months as it determines to be necessary. Submissions should bear the identifying The ITC also may designate chemicals Docket No. OPTS-41008. for priority consideration by EPA within EPA is experimenting~th its Chemical Recommended studies 12 months of the date of designation. approach to focusing issues and ChJorendIc acid 1EnvIronmental affects: The total number of designated encouragfug public involvement in CI8nIcaI la.e; 8CUI8 chemicals on the list may not exceed 50 responding to the ITC recommendations dvonIc toxic:ilyto IIsII and and has decided to hold public meetings aqua1Ic lnvettebnilU; tox. at anyone time. For each designated IcIty to aqualle macro- chemical EPA must. within 12 months. to obtain oral comment on the rrc's phytes. and alga.. Ninth Report only: (a) If requested to by 4-Ch1orobenzolr1l1uorid1J_1 Health affects: CIvonIc el. either initiate rulemaking or pub~ish in Iects. the Federal Register its reasons for not interested parties, and (b) ifEPA Envfronmental effects: so doing. concludes that public discussion will be ChemIcal late; bIocOnCen- useful in focusing and narrowing the Ir8IIon. D. Status of the IJat Tria (2oCh10r0ethyl)phosphIte IHealth effee1s: Phalmacokin- issues the Agency must address in aile and melabolic ltudies; 8Ubchronlc effects; repro- The ITC's Ninth Report. which was responding to the ITC's cax:tive effects. ~ceived by the Administrator on recommendations. Therefore. persons EnvIronmental effects: October 30, 1981. follows this Notice. In who believe that an informal meeting . ChamtcaI lata; acute toxic- Ity to 1IsII, aqualle Inverte- it. the rrc has added three chemicals to with EPA technical staff would be useful Inlas, and algae. the list. designating each for EPA action in achieving such focusing should call within 12 months. The chemicals added the Industry Assistance Office before are chlorendic acid (CAS No. 115-28-6). the close of the written comment period. As stipulated by section 4(e)(1)(B)of 4-chlorobenzotrifluoride (CAS No. 98- Any 8uch meetings. if held. will be open TSCA,each of the new 56-6) and tris (2-chloroethyl) phosphite to the public; however. active recommendations is being designated by (CAS No. 140-08-9). The Report also participation will be limited to those the Committee for action by the EPA noted the deletion from the list of four persons who requested the opportunity within 12months of the date of this previous entries. Dichloromethane. for informal discussions. Persons report. nitrobenzene, and 1.U-trichloroethane wishing to attend any such meetings Dichloromethane, nitrobenzene, 1.1.1- were removed from the list because EPA should notify the Industry Assistance trichloroethane, and the alkyltin

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compounds are "being removed from the numerous personnel of the Office of List. 34 were deferred from further lisL Toxic Substances. EPA. especially the consideration at this time. and 25are Industry Assistance Office. the still under review. TSCA Interagency Testing Committee Assessment Division. the Management As reported in the EighthITCReport Statutory Member Agencies and Their Support Division and the Health and (Ref.9), the Committee initiated. in the Representative. Environmental Review Division. Special latter part of 1980.a systematic Council on Environmental Quality, Gordon F. cognizance is given to Fwnihiko procedure for obtaining from the Snow. Member I Hayashi. Richard Tucker. and Larry chemical industry exposure and effects Department of Commerce. Orville B.P~ynter. Turner of the Health and Environmental data. The Committeelisted in the Member. Bernard Grelfer, Alternate Review Division for their timely review Federal Register (Ref.11)the 107 Environmental Protection Agency, Joseph of the environmental effects of Selfter. Member. earl R. Morris. chemicals selected in its 1980scoring Alternate chemicals studied by the C'ommittee. exercise for detailed review. The National Cancer Institute. Elizabeth K. Chapter 1-lntroduction Committeerequested comments on Welsburger, Member," Richard these chemicals to be presented either Adamson. Alternate. Jerrold Ward, 1.1 Background. The TSCA at a public meeting held November 6. Alternate Interagency Testing Committee 1980.or subsequently to be submitted in National bistitute of Environmental Health (Committee) was established under writing. Sciences, Dorothy Canter, Member I section 4(e) of the Toxic Substances To further encourage submission of National Institute for Occupational Safety Control Act of 1976 (TSCA. Pub. L. 94- relevant information on the chemicals and Health. Vera W. Hudson, Member 469). The specific mandate of the and Chairperson. Hebert B. Christensen,. being studied. letters were written to Alternate Committee is to identify and recommend manufacturers of the chemicals on the National Science Foudnation. Winston C. to the Administrator of the U.S. 1980list. inviting submission of data and Nottingham,Member . Environmental Protection Agency (EPA) information on exposure to and effects Occupational Safety and Health chemical substances or mixtures in commerce that should be tested to of the chemicals. Response to the Administration. Patricia Marlow. Committee's requests fromboth the Member and Vice Chairperson, LuclUe determine their potential hazard to public and private sectors has been Adamson. Alternate 4 human health and/or the environment. excellent. Information received from Liaison Agencies and Their Repl'86entatives TSCA specifies that the Committee's recommendations shall be in the form of chemical companies. trade associations Consumer Product Safety Commission, and governmental agencies has Arthur Gregory and Laksbmi Mlshra a Priority List. which is to be published increased the information base relied Department of Agriculture, Homer E. in the Federal Regiater. The Committee upon by the Committeein its review of Fairchild and Fred W. Clayton is directed to make revisions to the chemicals. Department of Defense. Arthur H. McCreesh Priority List. as it determines to be To date the Committeeand its Department of the Interior, Charles R. Walker necessary. and to transmit such Food and Drug Administration, Allen H. revisions to the EPA Administrator at technical support contractor have Heim and Winston deMonsabert least every 6 month8 after submission of contacted 72chemical manufacturers by National Toxicology Program. Dorothy the Initial List. letter and telephone. requesting Canter The Committee is comprised of information on 97.chemicals.Eighty-two Committee Staff representatives from eight statutory separate written responses were received from 41chemical companies Martin Greif. Executive Secretary member agencies. five liaison agencies, Vacant. Administrative Technician and one national program. The specific and trade associations. providing representatives and their affiliations are information on 90chemicals. The Support Staff named in the front of this report The information is being used by the Gary W. Dickson '-Office ofToxlc Committee's chemical review Committeein its deliberations, together Substances. EPA procedures and prior recommendations with that obtained from other sources. Ellen Slegier-Office of the General The Committeeis continuing the Counsel, EPA are described in previous reports (Refs. 1 through 9). practice of providing EPAwith copies of Edward Zillioux '-Office of Toxic all available data and information Substances. EPA 1.2 Committee'sprevious reports. . Eight previous reports to the EPA relevant to designated chemicals. References Administrator have been issued by the During this period the Committee (1) Dr. Snow was appointed on August 28, Committee and published in the Federal completed the development and 1982. Register (Refs. z through 9). Forty-six implementation of a computerized (2) Dr. We Isburger has previously served as entries (chemical substances and tracking system for chemicals it has an Alternate member and was appointed to ' categories of chemicals) have been considered since its inception. The full-member status on September 23, 1981. designated by the Committee for priority tracking system will be kept current as (3) Dr. Canter had previously served as an consideration by the EPA Administrator. additional chemicals are scored and Alternate member and was appointed to full- member status on July 8. 1981. One entry, chloromethane. was removed considered by the Committee. (4) Dr. L. Adamson terminated her fRef.8) after EPA responded to the 1.4 The TSCA section 4(e}Priority association with the' Committee on July 17, Committee's recommendation for List. Section 4{e){I){B)ofTSCA 1981. testing. authorizes the Committee to: ...·. (5) Dr. Dickson haa assisted the Committee 1.3 Committee's activities during make sure revisions in the priority list as since April 1981 and was appointed formally . this reporting period. The Committee it determines to be necessary and. · · to replace Dr. Zillloux on September 17. 1981. has continued to review chemicals from transmit them to the Administrator (6) Dr. ZiIIloux terminated his association its second and third rounds of scoring together with the Committee's reasons with the Committee on June 25. 1981. (see Ref. Z for methodology). During this for the revisions." Under this authority. The Committee acknowledges and is reporting period the Committee has the Committeeis revising the Priority grateful for the assistance and support evaluated 62 chemicals for priority List as follows: given to it by the staff of Enviro Control, consideration. Three were designated Three chemicals, chlorendic acid. 4- Inc. (technical support contractor) and for inclusion in the section 4(e) Priority chlorobenzotrifluoride. and tris(2-

HeinOnline-- 47 Fed. Rea. 5458 1982 Federal Register I Vol. 47, No. 25 I Friday, February 5, 1982 I Notices 5459 I ch1oroethyl)phosphite are added. The TABLE 1-TSCA SECTION4(e) PRIORITYltST- published by the Environmental Protection testing recommended for these Continued Agency. EPA 5~1~/001. January 1979. chemicals and the rationales for the (5) Fourth Report of the TSCA Interagency recommendations are presented in Date 01 designation Testing Committee to the Administrator, Chapter 2 of this report Environmental Protection Agency. TSCA 22. o-DIanIsIdIne-bas dyes_ November1979. Interagency Testing Committee. April 1979. Four entries are removed from the 23. 1,2.DicIIIoropropane October 1978. 24. Dlethylenetrlamlne AprIl19S1. . Published in the Federal Register of friday, Priority List. Three chemicals 25. FluoroaJkenes October 1980. June 1. 1979, 44 FR 31866-31889. (dichloromethane, nitrobeI17.ene, and 28. GIyddoIand Its dertvalivea-' October1978. (8) Fifth Report of the TSCA Interagency 1.l,1-trichloroethane) are removed 27. Halogen&ted a1ky18poxId88 AprIl 1978(b). 28. Haxechloro-l.3-bu1ac1ene 0ct0bIr 1977(a). Testing Committee to the Administrator. because the EPA Administrator has 29. HexachtooO(;)cIope"ladlene AprIl 1979. Environmental Protection Agency. TSCA responded "(Ref.10) to the Committee's 30. Hexachloroetllane April 1981. Interagency Testing Committee, November 31. Hycfroqulnone November 1979 recommendations in accordance with 32.1sophorone AprIl 1979. 1979. Published In the Federal Register of !fSCA section 4(e) requirements. In 33. MesItyt oxIde AprIl 1979. Friday. December 7.1979.44 FR 70664-70674. 34. 4.4.oMelhylenedianlllne April 1979. (7) Sixth Report of the TSCA Interagency addition, the Committee is withdrawing 35. Methyl etIIyI ketone April 1979. from the Priority List the alkyltin 36. Methyllsobutyt ketone April 1979. Testing Committee to the Administrator. compounds entry designated to the EPA 37. Phenytenedlamine8 April1980. Environmental Protection Agency. TSCA Administrator in the Committee's 38. PolychlorInatedllerphenyfs Apr11197S(b). Interagency Testing Committee. April 1980. 39. PyI1dIne.. . ApriI1978(b) Published In the Federal Register of Seventh Report (Ref. 8). Information on 40. 0uIn0ne November 1979 41. o-To~ dyes November 1979 Wednesday. May 28, 198(J,45 FR 35897-35910. alkyltins has recently becoDle available 42. T~ October 1977(8) (8) Seventh Report of the TSCA in the medical literature. through EPA's 43. Tris(2-chJorelhyQphcisphlte October 1981. Interagency Testing Committee to the 44. XyIenee October1977(a). Scoping Workshop (March 12. 1981), and Administrator, Environmental Protection through followup information-gathering (a) EPA AdnInistrator replied WI 43 FR 50134-60138. Agency. TSCA Interagency Testing EPA AdmInIsIraIof replied In 44 FA 2S095-2S097. Committee. October 1980. Published In the activities by EPA with the cooperation c EPA AdninIsIIatorreplied In 45 FR 48524-48564. of industry. other governmental ~ EPA AI1ministratorrepUed In 45 FR 48510-48512. Federal Register of Tuesday. November 25. agencies. and EPA contractors. In view 1980, 45 FR 78432-78446. of Ibis information, the Committee TABLE 2-REMOVALS FROMTHE TSCA (9) Eighth Report of the TSCA Interagency SECTION4(e) PRIORITYLIST concludes that the alkyltin compounds Testing Committee to the AdmfnistratOl'. Environmental Proteotion Agency. TSCA Gategory is too broad to be considered 0aIe 01removlll Interagency Testing Committee. April 1981. as a single category from the standpoint Published In the Fed8181RegIster of Friday. of ehemistry, exposure or effects. 1. AII

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Summary of rec(Jmmended studies. It Chlorendic acid is not expected to acid is estimated to be sufficiently slow is recommended that chlorendic acid be present an atmosplieric problem to persist in the environment. Chemical fested for the following: because of its low volatility. fate testing is recommended to permit Additionally. reactions with hydroxyl an understanding of movement and A. Environmental Effects: Chemicalfate. radicals and ozone. as well as direct compartmentalization of chlomedic acid Actue and chronic toxicity to fish and photolysis. should rapidly destroy any in the aquatic environment. These tests aquatic invertebrate.. chlorendic acid directly exposed to air can provide data on the potential Toxicity to aquatic macrophytes and algae. (Parlar and Korte. 1977;Parlar and exposure of aquatic organisms to Korte. 1979;and Shuphan et al.. 1972). chlorendic acid. as well as an estimate Physical and Chemicallnfonnalion Chlorendic acid may enter the of food-chain transport. environment in wastewater from No data were found on the toxicity of CASNumber:115-28-6. flameprooofmg processes in the textile chlorendic acid to aquatic organisms. Structural Fonnula: industry (Friedman et al.. 1974) and is There is concem with this compound expected to favor the aqueous because it is structurally similar to other compartment because of its solubility in highly chlorinated norbomene water. It is likely that chlorendic acid compounds. such as the pesticides win be formed as a degradation product . . , in soil containing and isodrin. . and . Therefore, pesticides having the it is recommended that chlorendic acid hexachlorobomene moiif (Martens. be tested for acute and chronic toxicity 1972: menzie, 1978). Chlorendic acid will to aquatic animals and plants. form also through hydrolysis of References chlorendic anhydride. Due to the insolubility of the anhydride at (1) Ashland. 1961. Communice.tlon from. environmental temperatures. This Ashland Chemical Company to Envlro Control, Inc., August 13. 1981. Empiricalformula:C.H.CI.O.. process will be slow (Velsicol.1968). With respect to biodegradation, (2) Berger. SA, McKay JB. 1975. The solvent MolecularWeight:388.87. extraction of Fe(ll) by chlorendlc acid. J. : 208-210. C (in sealed chlorendic acid would be expected to Inorg. Nucl. Chern. 37:2565-2567. behave like other highly chlorinated tube). . (3) EPA. 19S1.Environmental Protection norbornene compounds, which exhibit Agency. TSCA Chemical Substances 22.8°SolubilityC. in Water: 0.358/100 8 at considerable resistance to degradation. Inventory (public portion). Washington. D.C.: Chlorendic acid forms complexes with Environmental Protection Agency. Log Octanol/Water PlU'tition iron and may sorb to iron oxide colloids (4) Friedman M. Ash JF. Fox W. 1974. Coefficient: No information found. in sediments and soil (Berger and Dyebath application of chlorendic acid for Description of Chemical: Chlorendic McKay. 1975). Dame-resistant wool. Text. Res. J. 44:556- acid is a nearly odorless white Bolid. II. Environmental considerations-A. 5566. . Short-term (acute] effects. No studies on (5) Klrk-Othmer Encyclopedia of Chemical Rationale for Recommendatlono the short-term effect8 of chlorendic acid Technology. 2nd ed. 11171.Supplement. New York. NY: John Wiley and Sons, p. 480. I. Exposure information-A. have been found for either aquatic (8) Kirk-Othmer Encyclopedia of Chemical Production/use/disposal information. animals or plants. Technology, 3rd ed. Vol. 10. 1980. New York, Industrial use of chlorendic acid and the B. Long-term (subchronic/chronic] NY: John Wiley II

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Summaly of recommended studies. It effects. The acute toxicity of 4-chloro- daphnids (Hooker, 1981a). LCIIOvalues is recommended that 4-chlorobenzo- benzotrifluoride has been well were reported for bluegill sunfish (12.0 .~fluoride be tested for the following: characterized in rodents (Hooker. mg/L: 96 hr). rainbow trout (13.5 mg/L: 1981a). Oral LDIOvalues have been 96 hr), and Daphnia magna (12.4 mg/L: A. Health Effects: Chronic effects estimated to be greater than 6.8 g/kg in 48 hr). B. Environmental Effects: male and female Sprague-Dawley rats. . B.Long-term{subchronic/chranic} Chemical Fate A 4-hour acute inhalation study utilizing effects. A 21-day flow-through test was Bioconcentralion male and female Sprague-Dawley rats conducted with D. magna '(Hooker. yielded an estimated LCIOvalue of 33.0 1981a). The maximum allowable Physical and Chemical Information mg/L. toxicant concentration (MATC) was CASNumber:96-56-6. B. Short-term tests. Several short-term calculated to be 0.03-0.05 mg/L. Results Structural Formula: in vitro tests have been performed on 4- ~f a 3O-day embryo/larval test using chlorobenzotrifluoride and the following fathead minnows produced an MATC of results have been reported (Hooker, 0.54-1.40 mg/L (Hooker. 1981a). 1981a): C. Other effects {physiological/ Test Test results behaviorol/ecosystem processes}. Inhibition of six species of bacteria and (1) 5BImone11a typh/mutfum (TA-I535; TA- Negative. fungi was observed at concentrations 1537; TA-I538: TA-98: TA-I00). ranging from 31 to 8.000 ppm (Hooker, (2) EschetIch/s COli(W31101pol A'; P 3478{ Negative. pol A-j. 1981a). This data summary also reported (3) SscchIItomyr:ss -.1IisIa6 (0.) Negallve. inhibition of green and blue-green algal (4) Mouse lymphoma loIward mutauon assay Negative. Empirical Formula: C,H.CIF.. (TK locus In L5178Y cells). species at 500 ppm. Molecular Weight: 181. (5) Unscheduled DNA synthesis (EUE ceUS) POSIIIve. D. Bioconcentration and food-chain Meltins Point: -30. C. (8) In vI\Io transformaUon (BALB/3T3 cells)._ NegaUve. transport. The log of the octanol/water (7) 9sIer chrOmaIkI exchange (l5178Y Po&iIive. Vapor Pressure: 0 mm Hg at 25. C mouse Iymp/Iom8 cells). partition coefficient. estimated by (estimated). Hansch and Leo (1979), is 3.72 for 4- . Log Octanol/Water Partition Coefficient: chlorobenzotrifluoride. By the method of 3.72 (estimated). Details of the study designs and evaluation criteria were not available to Veith et a!. (1980), the bioconcentration factor i8 calculated to be 382 for 4- Description of Chemical: 4-Chloro- the Committeefor review. chlorobem:otriOuoride. benzobifluoride is a colorless liquid at C. Long-term (subchronic/chronic) room temperature (22° C). It has a low effects. No data are curreritly aVailable E. Rationale for environmental effects solubility in water and is 801uble in most to assess the long-term effects of 4- recommendations. Adequate testing has organic solvents. chlorobenzotrifluoride. A 9O-day been completed on the short-term (acute) and long-term (chronic) effects of Rationale for Recommendations 8ubchronic and reproductive study, by gavage in rats. has been proposed by a 4-chlorobenzotrifluoride on aquatic sponsor (Hooker, 1981b). The Committee organism8. The re8ults of these tests I. Exposure information-A. (Hooker. 1981a) indicates that 4-chloro Production/use/disposal information. has received no information concerning Between 10 million and 50 million the status of the study. . benzotrifiuoride is moderately toxic to fish and aquatic invertebrates. pounds of 4-chlorobenzotrifiuoride were D.Healtheffectsrecommendations. Based on the data provided by industry The compound may enter aquatic produced in 1977 (EPA. 1980). The systems through wastewater from chemical is used primarily as an (Hooker; 1981a) no further acute toxicity intermediate. It has been considered for testing is recommended. Since two of manufacture, solvent usage and through drainage from waste dump sites. Upon use as a solvent and as a dielecbic fluid the seven short-term in vitro tests were posltl~e. there are concerns about its reaching the aquatic environment, 4- (Hooker. 1981a). 4-Chlorobenzo- chlorobenzotrifiuoride is expected to be trifluoride appears to be released to the potential for chronic effects. The potential for 4-chlorobenzo- persistent because of the estimated low environment at production and use sites triOuoride to bioconcentrate is of rates of chemical and biological through wastewaters (Pellizari et al, concern because humans may be degradation (Adler et al, 1978). Chemical 1979: Hites. 1980;Yurawecz. 1979) and fate studies are recommended to through drainage from waste disposal chronically exposed to this chemical areas. The detection of 4- through its manufacture. use, and provide information necessary to chlorobenzotrlfiuoride at concentrations disposal. Since humans may be exposed quantify the environmental transport and compartmentalization of 4-chloro- of 0.17-2.0 ppm in edible portions of through the food chain. as suggested in the following section on Environmental benzotrifiuoride. three species of freshwater fish Considerations, there is concern for Because of the relatively high (Yurawecz. 1979)provides further evidence that there is environmental chronic human health effects. Based on calculated log octanol/water partition these considerations, 4- coefficient, 4-chlorobenzotrifiuoride is exposure to this chemical. chlorobenzotrifluoride is recommended expected to bioconcentrate in fatty B. Chemical fate information. No test for chronic toxicity testing. The tissues of living organisms. Yurawecz data on the environmental transport or Committee believes. however, that prior (1979) detected 4-chlorobenzotrifluoride persistence of 4-chlorobenzotrifluoride to conducting long-term chronic testing, at concemtrations ranging from 0.17 to have been identified. The chemical is there should be a clarification and 2.0 ppm in the edible portion of three sufficiently volatile to enter the subsequent review of the protocols and species of freshwater fish (white bass, atmosphere. Based on its chemical criteria used for the short-term tests smallmouth bass. and yellow perch) structure. it is expected to resist summarized above. collected from Niagara River. This degradation. persist in the environment. III. Environmental considerations-A. potential for bioconcentration increases and bioconcentrate (see section mo. Short-term (acute) effects. Acute concern for the efrects of food chain II. Biological effects of concern to toxicity tests have been conducted transport of 4-chlorobenzotrifluoride. human health-A. Short-term (acute) under static conditions in fish and For these reasons and the expected

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environmental entry routes, it is Solubility: Hydrolyzed in water; severe corneal. iridial. and conjunctival recommended that testing be conducted soluble in organic solvents. Including effects in rabbit eyes: more than 7 days to detennine the bioconcentration of 4- . alcohols. , ether, and was required for recovery. (Olin. 1981). chlorobf:nzotrifluoride. In rats. the acute inhalation LCIIOwas References LogOctanol/Wat81PiU'tltiollCoefficient: greated than 5.0mg/L in both male and <2 (e6tlmated). (I) Adler lL, Haines LD. Jones BM. 1978. female rats. There was 20 percent Description:Colorlessliquid with a mortality in female rats exposed at 5.0 Gas-liquid chromatographic determination of characteristic odor. . residues from the herbicide 2-chloro-l-(3- mg/L for 4 hours. but none in males. athoxy-4-nitrophenoxY)-4-(liinuoromcthyl) Rationale for Recommendations Both sexes displayed physical signs of b!:i!.7eo':!.j. Assoe. Off. Anal. Chem: 61(3): I.Exposure information-A. toxicity. (Stauffer, 1981b). 636-6J9. . In both rats and rabbits. tris(2- (21 EPA. 198D. Environmental Protection Production and use in{orma,~ion.The Agency. TSCA Chemical Substances public portion of the TSCA Chemical chloroethyl)phosphite l~d to decreases L-:ve~i:::y [public portion). Washington, D.C.: Subst3nces Inventory discloses in cholinesteraae levels in either red ~lvir;;~r.'~:Ital Protection i\fjency. aggregate prod~1ctlon by three blood cells or plasma. (OHn,1981). [3) H. '!.s.:hC.LeoA. 1979.Substitute manufacture~ in 1977 of between 2.1 In view of the variance in reported constar.ts for correlation analysis In and 21 million pounds in the United acute toxicity levels. as well as the cht:mlstry and biology. New York. NY: p. 339. States (EPA, 1981). Tris(2-chloroethyll difference in response of male and fol) fiHes RA. 1980. Identiflcatior, of !!nvirnr:r.;",p!1i1 contaminants. Prt:sented at phosphite is an intermedhtr. in the female rats. subchronic studies of the the S)-rr.pD~lurt' on Mass Spectrom:!Uy. Food manufacture uf various pho!;phorous- toxicity of tris(2-chlo!'oethyl)phosphite 'lnd Drug A:!rr:inI6tr!.Uun. Washington. DC. containing monomers, including latexes. are recommended. . OC!Obf:T 16, 1980. fonns, adhesives, aud coatings (Kirk- B. Mutagenicity. TriIl(2- :51 H'1!Jk

HeinOnline -- 47 Fed. Rea. 5462 1982 Federal Register I Vol. 47. No. 25 I Friday, February 5, 1982 I Notices 5463 chloroethyl)phosphite have been found product, and the paucity of toxicity test United Steamship Company (Bahamas) for either aquatic animals ,or plants. data on tris(2-chloroethyl)phosphite. Ltd. and Scandinavian World Cruises B. Long-term{subchronic/ References (Bahamas) Limited chronic)effects. No studies on the long- (1) ACGIH. 1981. American Conference of c/o Scandinavian World Cruises, 1441 term effects of bis(2- . Governmental Industrial Hygienists. TLVs8 Port Boulevard, Port of Miami,Miami, chloroethyl)phosphite have been found Threshold Umit Values for Chemical Florida 33132 for either aquatic animals or plants. , Substances and PhysicalAgents in the C. Other effects (physiological/ Workroom Environment with Intended Dated: February Z. 1962. behaviorol/ecosystem processes). No Changes for 1981. Cincinnati, OH. Francis C. Hurney, studies on physiological, behavioral, or (2) EPA. 19S1.Environmental Protection Secretary. ecosystem effects of tris(2- Agency. TSCA Chemical Substances [FRDoc.f!3-3015 PlIed ~ 8:45 am) dJloroethyl)phosphite have been found. Inventory (public portion). Washington, DC: BILLING CODE S730-01~ D. Bioconcentration and food-chain Environmental Protection Agency. (3) Fuhrman FA. Field J. Wilson RH, Deeds transport. Because of chemical structure, F. 1965. Monochloroacetate: effects of chronic there is no reliable way to e9timate the administration to rats on growth. activity and FEDERAL RESERVE SYSTEM log octanol/water partition coefficient tissue metabolism and Inhibitory effects In (log P) for this compound. However, vitro compared with monolodoacetate and Banque Natlonale de Paris; based upon solubility characteristics monobromoacetate. Arch. InL Pharmacodyn. Corporation To Do Business Under and comparisons with other data (Leo et 52:113-125. Section 25(a) of the Federal Reserve aJ., 1971), tris(2-chloroethyl)phosphite is (4) Imaev MG. 1961a. The saponification of Act expected to have a log P of less than 2 full esters of phosphorous acid by pure'water. (Veith, 1981). Because of the relatively Zh. Obsh. Khim. 31(b): 1762-1766. (English An application has been submitted for low log P estimates and the anticipated translation pp. 164~1650). the Board's approval of the organization rapid in vivo hydrolysis (Smith et al., (5) Imaev MG. 1961b. The saponification of of a corporation to do business under trlalkyl phosphltes In the presence of 1933, Imaev, 1961b), bis(2- section 25(a) of the Federal Reserve Act inorganic and organic bases. Zh. Obilh. KhIm. ("Edge Corporation"), to be known as chloroethyl)phosphite is not expected to 31: 1767-1770. (English translation pp. 1651- bioconcentrate significantly in fatty 1653). BNP International Corp., Houston. tissues. This compound is likely to bind (8) Innes JRM.Ulland BM, Valerio MG, et Texas. BNP International Corp. would to sediments and thus have the potential al. 1969. Bioassay of pesticides and industrial operate as a subsidiary of Banque to be transported along the food chain. chemicals for tumorigenicity in mice: a Nationale de Paris, Paris, France. The No data were found on food-chain preliminary note. J. Natl. Cancer Inst. factors that are considered in acting on 42:1101-1114. transport. ' the application are set forth in § 211.4(a) E. Reasons for specific environmental (7) Klrk-Othmer Encyclopedia of Chemical of the Board's Regulation K (12CPR Technology, 3rd ed., Vol. 10. 1970. New York: 211.4(a)). effects recommendations. The reported John Wiley and Sons. pp. 403-410. use/ disposal pattern of tris(2- (8) Leo L. Hansch C. Elkins D. 1971. The application may be inspected at chloroethyl)phosphite indicates that the Partition coefficients 'and their uses. Chern. the offices of the Board of Governors or primary exposure to this compound will Rev.71:525-e16, ' at the Federal Reserve Bank of San occur in the aquatic environmenllt is (9) Mobil Chemical Company. 1980. Francisco. Any person wishing to expected to enter the aquatic Comments on proposed rules for general , comment on the application should environment through manufacturers' recordkeeping and reporting requirements submit views in writing to the Secretary, and processors' wastewater and through under section 8(a) ofTSCA. Board of Governors of the Federal degradation of polymers. . (10) NTP. 1981a. Natioh~ Toxicology Reserve System, Washington, D.C. 20551 Program. Communication to E. K. Weisburger. Studies of similar bialkyl phosphites March 30. 1981. to be received no later than February 28, (Imaev, 1961a, 1961b) indicatc that 1982. Any comment on an application tris(2-chloroethyl)phosphite will be )PRDoc.BZ-3071PlIedz..+.82:8:45eml SIWNG CODE 1580-31-M that requests a hearing must include a rapidly hydrolyzed (estimated minutes statement of why a written presentation to hours) in water to a potentially toxic would not suffice in lieu of a hearing, compound, 2-chloroethanol. Sorption of FEDERAL'MARITIMECOMMISSION identify specifically any questions of tris[2-chloroethyl)phosphite to fact that are in dispute and summarize sediments may impede hydrolysis. SecurIty for the Protection of the the evidence that would be presented at Chemical fate testing is recommended to Public Financial Responsibility To a hearing. permit an understanding of the Meet Uablllty Incurred for Death or Board of Governors of the Federal Reserve movement and compartmentalization of Injury to Passengers or Other Persons System.January 29,1962. tris(2-chloroethyl)phosphite in the on Voyages; Application for Certificate Theodore E. Downing, Jr.. aquatic environment. These tcsts can [Casualty] provide data on the expected rate of Assistant Secretary of the Board. hydrolysis to 2-chloroethanoJ. In Notice is hereby given that the )PRDoc.8Z-3028PlIed~ 8:45ami addition. chemical fate testing will following persons have applied to the BlWNGCODE1210-01~ permit estimates of the sorption of tris(2- Federal Maritime Commission for a chloroethyl)phosphite to sediments and Certificate of Financial Responsibility to its effect on hydrolysis and potential Meet LiabiHty Incurred for Death or Bay-Hermann Bancshares, Inc.; food chain transporl Injury to Passengers or Other Persons on Formation of Bank Holding Company No test data were located on the Voyages pursuant to the provisions of Bay-Hermann Bancshares, Inc., toxicity of tris(2-chloroethyl)phosphite Section 2,Pub.L.89-777(80Stat. 1356, Hermann,Missouri,has applied forthe to aquatic organisms. Acute toxicity 1357) and Federal Maritime Commission Board's approval under section'3(a)(1)of tests in fish, aquatic invertebr.ates, and General Order 20,as amended (46CPR the Bank Holding Company Act (12 algae are recommended because of the Part 540): U.S.C.1842(a)(1))to become a bank aquatic exposure anticipated, the DFDS Seaways (Bahamas) Ltd., holding company by acquiring 80 apparent toxicity of a degradation DFDS Seacrulses (Bahamas) Ltd., percent or more of the voting shares of

HeinOnline-- 47 Fed. Req. 5463 1982