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An International Journal Nature and Science ISSN 1545-0740 Volume 8 - Number 5 (Cumulated No. 38), May 1, 2010 Marsland Press P.O. Box 21126, Lansing, Michigan 48909, USA 525 Rockaway PKWY, #B44, Brooklyn, New York, 11212, USA http://www.sciencepub.net http://www.sciencepub.org [email protected] [email protected] 347-321-7172 http://www.sciencepub.net [email protected] Nature and Science ISSN 1545-0740 Nature and Science ISSN: 1545-0740 The Nature and Science is an international journal with a purpose to enhance our natural and scientific knowledge dissemination in the world under the free publication principle. Papers submitted could be reviews, objective descriptions, research reports, opinions/debates, news, letters, and other types of writings that are nature and science related. All manuscripts submitted will be peer reviewed and the valuable papers will be considered for the publication after the peer review. The Authors are responsible to the contents of their articles. 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References should include all the authors’ last names and initials, title, journal, year, volume, issue, and pages etc. ISSN: 1545-0740 ã 2003-2011 Marsland Press http://www.sciencepub.net [email protected] Nature and Science ISSN: 1545-0740 Volume 8 - Number 5 (Cumulated No. 38), May 1, 2010 Cover Page, Introduction, Contents, Call for Papers, All in one file All comments are welcome: [email protected] Welcome to send your manuscript(s) to: [email protected] CONTENTS Full No. Titles / Authors Text Histopathologic study of the Antiestrogenic Nolvadex Induced Liver Damage in Rats and Vitamins Full Ameliorative Effect Text Fatma A. Morsy, Amina Gamal el Din, Nermeen M. Shaffie and Manal A. Badawi Department of Pathology, National Research Center, Dokki, Cairo, 12622, Egypt [email protected] ABSTRACT: This study was designed to evaluate the effects of antiestrogenic Nolvadex (used for breast cancer treatment) on rat liver and the possible protective effects of vitamin C and/ or E. Material and methods: A total of 140 adult female albino rats were used; divided into seven groups; each containing 20 rats: First group: as control. Second group: orally daily dosed with Nolvadex 20 mg/kg b. w. for three weeks. Third group: orally given vitamin C (0.02 g/100 g b wt), 15 min before daily Nolvadex administration. Fourth group: given vitamin E (120 mg/Kg b.w), 15 min prior to daily Nolvadex administration. The fifth group was given combination of the two vitamins C 1 & E (0.02 g/100 g b.w.) and (120 mg/kg b.w.) respectively, 15 min before daily Nolvadex administration. Each of the remaining two groups was daily given vitamin C (0.02 g/100 g b.w.) and/or E (120 mg/kg b.w.) for two weeks. Paraffin sections were used for histopathological , quantitative image analysis DNA ploidy and histochemical studies .Electron microscopy was performed. Results: Histopathological degenerative effects in the form of vacuolar degeneration, fatty changes and hydropic degeneration were noticed in Nolvadex treated rat liver. Karyolysis and karyorrhexis were also seen.Dysplasia and chromatin clumping were observed in scattered hepatocytes together with a decrease in DNA content (hypoploidy) and marked diminution of protein and mucopolysaccharides content.Histopathological, histochemical and ultra structural changes were diminished in rats treated with vitamins C and/ or E prior to Nolvadex. Conclusion: The treatment of rats with vitamins C and/or E prior to Nolvadex resulted in amelioration of the histopathological ,histochemical and ultrastructural changes of liver. [Nature and Science. 2010;8(5):1-15]. (ISSN: 1545-0740). Key words: Histopathology – antiestrogenic - Nolvadex – liver – rat – Vitamins The effects of farmyard manure on the dry matter components of two cucumber varieties Full Text Eifediyi, E. K ; S. U. Remison and V. B. Okaka 2 Dept. of Crop Science, Ambrose Alli University P. M.B. 14, Ekpoma, Nigeria Email: keveifediyi@ yahoo.com Abstract: The effects of farmyard manure on the dry matter content of two cucumber varieties (Ashley and Palmetto) was evaluated at the Teaching and Research Farm of the Ambrose Alli University, Ekpoma, Nigeria Lat 6o 451 N and Long 6o 081E..The farmyard manure was applied at the rates of 0, 5 and 10t/ha. The layout was a 2 x 3 factorial scheme with three replicates. The result of the study showed that increasing the farmyard rates led to an increase in the dry matter weights of the two varieties of cucumber. Farmyard manure at 10t/ha increased the dry matter content of cucumber. Palmetto was however more responsive to FYM application, with the rate of 10t/ha out yielding the control by 60% in contrast to Ashley, in which 10t/ha of FYM out yielded the control by only 30 %. [Nature and Science. 2010;8(5):16-22]. (ISSN: 1545-0740). Keywords: Farmyard manure, two cucumber varieties, dry matter accumulation and yield Study effect drought stress and different levels potassium fertilizer on K+ accumulation in corn Full Text Shirin Dastbandan Nejad1, Tayeb Saki Nejad2, Shahram Lack3 1- Master graduate of science and Research University, Khuzestan Branch 2-Assistant professor Department of agronomy & physiology, Islamic Azad University, Ahvaz Branch 3-Assistant professor Department of agronomy, science and Research University, Khuzestan Branch *Corresponding Arthur [email protected] Abstract: the necessity of exertion of irrigation regimes proportional to absorb process of nutritious element of potassium appear necessary duo to famine periods, saltines problem, and the shortage of drainage irrigation net in 3 agricultural lands of Khuzestan province(southwest of Iran). This research is performed in the form of split plot test in accidentally complete bloke plan (main treatment: various levels in irrigation I. = 7, I1 =12, I2 = 17, I3 = 22 day and secondary treatment: potassium fertilizer various levels K1 =50, K2= 100, and K3=150(kg/ h) with 3 repetition. Plant date of first half of 2008 August is done in Shahid Salami irrigation institute farm in Ahvaz County.