DOCSLIB.ORG

Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery SURGICAL INFECTIONS Volume 14, Number 1, 2013 Surgical Infection Mary Ann Liebert, Inc. DOI: 10.1089/sur.2013.9999 Society Guidelines Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery Dale W. Bratzler,1 E. Patchen Dellinger,2 Keith M. Olsen,3 Trish M. Perl,4 Paul G. Auwaerter,5 Maureen K. Bolon,6 Douglas N. Fish,7 Lena M. Napolitano,8 Robert G. Sawyer,9 Douglas Slain,10 James P. Steinberg,11 and Robert A. Weinstein12 hese guidelines were developed jointly by the Ameri- the project. Panel members and contractors were required to Tcan Society of Health-System Pharmacists (ASHP), the disclose any possible conflicts of interest before their ap- Infectious Diseases Society of America (IDSA), the Surgical pointment and throughout the guideline development pro- Infection Society (SIS), and the Society for Healthcare Epide- cess. Drafted documents for each surgical procedural section miology of America (SHEA). This work represents an update were reviewed by the expert panel and, once revised, were to the previously published ASHP Therapeutic Guidelines on available for public comment on the ASHP website. After Antimicrobial Prophylaxis in Surgery [1], as well as guide- additional revisions were made to address reviewer com- lines from IDSA and SIS [2,3]. The guidelines are intended to ments, the final document was approved by the expert panel provide practitioners with a standardized approach to the and the boards of directors of the above-named organizations. rational, safe, and effective use of antimicrobial agents for the prevention of surgical site infections (SSIs) based on currently Strength of evidence and grading of recommendations available clinical evidence and emerging issues. The primary literature from the previous ASHP Therapeutic Prophylaxis refers to the prevention of an infection and can Guidelines on Antimicrobial Prophylaxis in Surgery [1] was be characterized as primary prophylaxis, secondary prophy- reviewed together with the primary literature published be- laxis, or eradication. Primary prophylaxis refers to the pre- tween the date of the previous guidelines, 1999, and June 2010, vention of an initial infection. Secondary prophylaxis refers to identified by searches of MEDLINE, EMBASE, and the Co- the prevention of recurrence or reactivation of a preexisting chrane Database of Systematic Reviews. Particular attention infection. Eradication refers to the elimination of a colonized was paid to study design, with greatest credence given to organism to prevent the development of an infection. These randomized, controlled, double-blind studies. There is a lim- guidelines focus on primary perioperative prophylaxis. ited number of adequately powered randomized controlled trials evaluating the efficacy of antimicrobial prophylaxis in Guidelines development and use surgical procedures. Guidelines development included con- Members of ASHP, IDSA, SIS, and SHEA were appointed sideration of the following characteristics: validity, reliability, to serve on an expert panel established to ensure the validity, clinical applicability, flexibility, clarity, and a multidisciplinary reliability, and utility of the revised guidelines. The work of nature as consistent with ASHP’s philosophy on therapeutic the panel was facilitated by faculty of the University of guidelines [4]. The limitations of the evidence base are noted Pittsburgh School of Pharmacy and University of Pittsburgh within each individual procedure section of the guidelines. Medical Center Drug Use and Disease State Management Published guidelines with recommendations by experts in a Program who served as contract researchers and writers for procedure area (e.g., American College of Obstetricians and 1College of Public Health, and Professor, College of Medicine, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma. 2Department of Surgery, and Chief, Division of General Surgery, University of Washington, Seattle, Washington. 3Nebraska Medical Center, Omaha, Nebraska. 4Pathology, and Epidemiology, Johns Hopkins University, and Senior Epidemiologist, The Johns Hopkins Health System, Baltimore, Maryland. 5Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, Maryland. 6Division of Infectious Diseases, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. 7Department of Clinical Pharmacy, University of Colorado, Anschultz Medical Campus, and Clinical Specialist, Critical Care/Infectious Diseases, Department of Pharmacy Services, University of Colorado Hospital, Aurora, Colorado. 8Acute Care Surgery, Trauma, Burn, Critical Care, Emergency Surgery, and Associate Chair of Surgery, Critical Care, Department of Surgery, and Director, Surgical Critical Care, University of Michigan Health System, Ann Arbor, Michigan. 9Public Health Sciences, and Chief, Division of Acute Care Surgery and Outcomes Research, University of Virginia Health System, Charlottesville, Virginia. 10Pharmacy and Medicine, West Virginia University, Morgantown, West Virginia. 11Division of Infectious Diseases, Emory University, Atlanta, Georgia. 12Rush Medical College, Chicago, and Chairman, Department of Medicine, Cook County Health and Hospital System, Chicago, Illinois. Copyright ª 2013, American Society of Health-System Pharmacists, Inc. All rights reserved. 1079-2082/13/0201-0195$06.00. 73 74 SURGICAL PROPHYLAXIS GUIDELINES Gynecologists [ACOG]) and noted general guidelines (e.g., U.S. Preoperative-dose timing. The optimal time for admin- Centers for Disease Control and Prevention [CDC], Scottish istration of preoperative doses is within 60 min before surgi- Intercollegiate Guidelines Network, Medical Letter,SIS,SHEA/ cal incision. This is a more-specific time frame than the IDSA) were also considered [2,3,5–11]. previously recommended time, which was ‘‘at induction of Recommendations for the use of antimicrobial prophylaxis anesthesia.’’ Some agents, such as fluoroquinolones and are graded according to the strength of evidence available. The vancomycin, require administration over one to two hours; strength of evidence represents only support for or against therefore, the administration of these agents should begin prophylaxis and does not apply to the antimicrobial agent, dose, within 120 min before surgical incision. or dosage regimen. Studies supporting the recommendations for the use of antimicrobial therapy were classified as follows: Selection and dosing. Information is included regarding the approach to weight-based dosing in obese patients and the Level I (evidence from large, well-conducted, random- need for repeat doses during prolonged procedures [13–18]. ized, controlled clinical trials or a meta-analysis), Obesity has been linked to an increased risk for SSI. The Level II (evidence from small, well-conducted, ran- pharmacokinetics of drugs may be altered in obese patients, so domized, controlled clinical trials), dosage adjustments based on body weight may be warranted Level III (evidence from well-conducted cohort studies), in these patients. For all patients, intraoperative redosing is Level IV (evidence from well-conducted case–control needed to ensure adequate serum and tissue concentrations of studies), the antimicrobial if the duration of the procedure exceeds two Level V (evidence from uncontrolled studies that were half-lives of the drug or there is excessive blood loss during the not well conducted), procedure (Table 1). Recommendations for selection of anti- Level VI (conflicting evidence that tends to favor the microbial agents for specific surgical procedures and alterna- recommendation), or tive agents (e.g., for patients with allergies to b-lactam Level VII (expert opinion or data extrapolated from antimicrobials) are provided in Table 2. evidence for general principles and other procedures). Duration of prophylaxis. This system has been used by the Agency for Healthcare New recommendations for a Research and Quality, and ASHP, IDSA, SIS, and SHEA shortened postoperative course of antimicrobials involving a support it as an acceptable method for organizing strength of single dose or continuation for less than 24 hours are pro- evidence for a variety of therapeutic or diagnostic recom- vided. Further clarity on the lack of need for postoperative mendations [4]. Each recommendation was categorized ac- antimicrobial prophylaxis based on the presence of indwell- cording to the strength of evidence that supports the use or ing drains and intravascular catheters is included. nonuse of antimicrobial prophylaxis as category A (levels Common principles. A section addressing concepts that I–III), category B (levels IV–VI), or category C (level VII). apply to all types of surgical procedures has been added. When higher-level data are not available, a category C Expanded and new recommendations are provided for plas- recommendation represents a consensus of expert panel tic, urology, cardiac, and thoracic procedures, as well as members based on their clinical experience, extrapolation clarity on prophylaxis when implantable devices are inserted. from other procedures with similar microbial or other clinical The latest information on the use of mupirocin and on the role features, and available published literature. In these cases, the of vancomycin in surgical prophylaxis is summarized in these expert panel also extrapolated general principles and evi- updated guidelines. dence from other procedures. Some recommendations in- clude alternative approaches in situations in which panel Application of
Load more

Recommended publications
  • Gas-Phase Broadband Spectroscopy Using Active Sources: Progress, Status, and Applications [Invited]
    104 Vol. 34, No. 1 / January 2017 / Journal of the Optical Society of America B Review Gas-phase broadband spectroscopy using active sources: progress, status, and applications [Invited] 1, 1,4 2 2 KEVIN C. COSSEL, *ELEANOR M. WAXMAN, IAN A. FINNERAN, GEOFFREY A. BLAKE, 3 1 JUN YE, AND NATHAN R. NEWBURY 1National Institute of Standards and Technology, 325 Broadway, Boulder, Colorado 80305, USA 2Division of Chemistry & Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA 3JILA, National Institute of Standards and Technology and University of Colorado, Department of Physics, University of Colorado, Boulder, Colorado 80309, USA 4e-mail: [email protected] *Corresponding author: [email protected] Received 19 September 2016; revised 1 November 2016; accepted 15 November 2016; posted 15 November 2016 (Doc. ID 275946); published 14 December 2016 Broadband spectroscopy is an invaluable tool for measuring multiple gas-phase species simultaneously. In this work we review basic techniques, implementations, and current applications for broadband spectroscopy. We discuss com- ponents of broadband spectroscopy including light sources, absorption cells, and detection methods and then discuss specific combinations of these components in commonly used techniques. We finish this review by discussing po- tential future advances in techniques and applications of broadband spectroscopy. © 2016 Optical Society of America OCIS codes: (300.1030) Absorption; (120.6200) Spectrometers and spectroscopic instrumentation; (120.4640) Optical instruments; (300.6390) Spectroscopy, molecular. https://doi.org/10.1364/JOSAB.34.000104 1. INTRODUCTION spectral bandwidth allows for the simultaneous detection of Molecular spectroscopy has been shown to be a powerful multiple species. This enables a single instrument to serve many analytical tool with a wide range of applications.
    [Show full text]
  • IP Owner's Q & A, Sorted X Subject
    Sorted by Subject Island Packet Owner's Q & A Report on Tenders Barnacle Rings On Avon Inflatable From: Clark Chalifour Received: 3/12/2002 11:55:18 AM Last season, I left my Avon inflatable in the water too long and ended up with many barnacles on its bottom. I removed the barnacles with a black Scotch pad (the type used on grills), but rings from the barnacles remain. I am hesitant to use products intended for removing barnacle rings from fiberglass hulls on a fabric inflatable. Does anyone have any experience or suggestions with respect to removing such rings from an inflatable? Clark Chalifour WINDHOVER IP-27-198 From: Don Berger Received: 3/12/2002 1:17:11 PM WM sells dilute hydrochloric acid under some obvious brand name I can't recall just now and it is advertized as safe. More important, I've used it and it works great. Hypalon and PVC are both impervious to HCL; my only reservation had been to keep it away from the seams (which isn't that difficult) as I am not sure how it would affect the glue. Don From: Sherri & Glen Wells Received: 3/13/2002 7:33:35 AM You probably won't like my method but it works. Deflate the dinghy and roll the PVC or Hapalon with your fingers as to fracture and dislodge the rings. Sometimes a plastic scraper used for snow removal can assist. I also grew a healthy crop. After this tedious effort of Cirripedia removal a priorety was established. Get the dink out of the water! Captain Glenn Lady Ann IP-32 #120 From: Al Sandman Received: 3/13/2002 8:03:43 AM Just try using liquid bleach, I have used it for years, it seems to work better than any other product I tried.
    [Show full text]
  • Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery
    SURGICAL INFECTIONS Volume 14, Number 1, 2013 Surgical Infection Mary Ann Liebert, Inc. DOI: 10.1089/sur.2013.9999 Society Guidelines Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery Dale W. Bratzler,1 E. Patchen Dellinger,2 Keith M. Olsen,3 Trish M. Perl,4 Paul G. Auwaerter,5 Maureen K. Bolon,6 Douglas N. Fish,7 Lena M. Napolitano,8 Robert G. Sawyer,9 Douglas Slain,10 James P. Steinberg,11 and Robert A. Weinstein12 hese guidelines were developed jointly by the Ameri- the project. Panel members and contractors were required to Tcan Society of Health-System Pharmacists (ASHP), the disclose any possible conflicts of interest before their ap- Infectious Diseases Society of America (IDSA), the Surgical pointment and throughout the guideline development pro- Infection Society (SIS), and the Society for Healthcare Epide- cess. Drafted documents for each surgical procedural section miology of America (SHEA). This work represents an update were reviewed by the expert panel and, once revised, were to the previously published ASHP Therapeutic Guidelines on available for public comment on the ASHP website. After Antimicrobial Prophylaxis in Surgery [1], as well as guide- additional revisions were made to address reviewer com- lines from IDSA and SIS [2,3]. The guidelines are intended to ments, the final document was approved by the expert panel provide practitioners with a standardized approach to the and the boards of directors of the above-named organizations. rational, safe, and effective use of antimicrobial agents for the prevention of surgical site infections (SSIs) based on currently Strength of evidence and grading of recommendations available clinical evidence and emerging issues.
    [Show full text]
  • The Sailing Magazine for the Rest of Us
    The sailing magazine for the rest of us. 10 00 00 $8 (Canada $8 CDN) 10 0 62825 97035 7 goodoldboat.com Issue 128 September/October 2019 Automatic/Manual Inflatable PFD USCG Approved Type V with Type II Performance! Full 35 lbs buoyancy! Comfortable, low profile, with wide neoprene neckline. Universal sizing, fits 30"-65" chest. Hi-Vis inflation chamber. Durable 400 denier nylon. Super bright retro-reflective areas on front and a high-visibility BEACON logo on the back. H Reg 179.99 HAMILTON SAVE $ 99 $30 NEW! 149 ea Pre-order MARINE Part# Color Order# ™ HMI-BCNI35OG Orange/Gray 773536 today! HMI-BCNI35BG Blue/Light Gray 773535 BOATERS' STORE! Moisture Absorber Dries air in cabins, lockers, closets, rooms, basements and other enclosed State-of-the-art line areas. Super-dry concentrated pellet of premium coatings, formula absorbs up to 50% more adhesives and putties. moisture than flake formulas. Search# SYT- $ 29 7 ea MK-6912 Order# 144114 Hamilton Wayne Photo by Tea Tree Power® Mold & Mildew Eliminator Non-toxic, bio-degradable. Blended from 100% Australian tea tree oil. Available in gel or spray. Tarps Starting At • Lightweight Blue 3 GRADES, $ 99 • Premium White 27 SIZES! 17 ea • Super Heavy Duty Silver HAMILTON Search# FOR-77020 Search# STT- Premium 7 Mil. White Oil Absorbent Sheets Shrink Wrap Each 15" x 19" sheet CAN HELP! absorbs 13 to 25 times Some sizes are available its weight in oil, fuel Many Hamilton Marine employees maintain in clear and blue. Shrink and other hydrocar- their own boats. And there is no better teacher wrap accessories are also bons.
    [Show full text]
  • 49Thannual UNITED STATES SAILBOAT SHOW
    49th ANNUAL UNITED STATES SAILBOAT SHOW October 4 – 8, 2018 EXHIBITOR MOVE-IN BULLETIN 110 Compromise Street, Suite 500 Annapolis, MD 21401 410-268-8828 This bulletin contains final set-up and move-in information for the 2018 United States Sailboat Show. PLEASE CHECK YOUR MOVE-IN DAY AND TIME and it is imperative that boats in the water and on land be ready to proceed into their designated spaces at the time allotted to them. If boats in the water are not ready to go into their dock space at the assigned time, they will be bypassed. If space is available, the bypassed boats may be reassigned. If boats on land are not ready to load into their land space at the allotted time, they will be taken only as time and space allows (this may mean a lengthy wait). SHOW OFFICE HAS MOVED The show office is located in our new permanent office 110 Compromise Street, Suite 500 PLEASE MAKE SURE YOU HAVE SUBMITTED THE FOLLOWING: Signed Contract Final Payment Exhibitor's Credentials Request Insurance Certificate Copy of MD Traders License or Exhibitor's Affidavit Manufacturer's Dealer Information Ticket Order Forms IMPORTANT PHONE NUMBERS! Show Office 410-268-8828 Fax # 410-280-3903 EXHIBITOR'S LOUNGE The Annapolis Fleet Reserve Club has again made its facilities available to exhibitors at the sailboat and powerboat shows. The Lounge will be open for breakfast, buffet lunch, and bar service during set-up, show days and tear-down of both shows. The Fleet Reserve Club is on Compromise Street between Tent D and the Annapolis Waterfront Hotel.
    [Show full text]
  • Usss Movein 2014
    45th ANNUAL UNITED STATES SAILBOAT SHOW October 9 – 13, 2014 EXHIBITOR MOVE-IN BULLETIN 980 Awald Road, Suite 302, Annapolis, MD 21403 410-268-8828 This bulletin contains final set-up and move-in information for the 2014 United States Sailboat Show. PLEASE CHECK YOUR MOVE-IN DAY AND TIME and it is imperative that boats in the water and on land be ready to proceed into their designated spaces at the time allotted to them. If boats in the water are not ready to go into their dock space at the assigned time, they will be bypassed. If space is available, the bypassed boats may be reassigned. If boats on land are not ready to load into their land space at the allotted time, they will be taken only as time and space allows (this may mean a lengthy wait). PLEASE MAKE SURE YOU HAVE SUBMITTED THE FOLLOWING: Signed Contract Final Payment Exhibitor's Credentials Request Insurance Certificate MD Traders License or Exhibitor's Affidavit Manufacturer's Dealer Information Ticket Order Forms IMPORTANT PHONE NUMBERS! Permanent Show Office 410-268-8828 Permanent Fax # 410-280-3903 Show Office (Oct. 6 - 19) 410-280-5317 Fax at show (Oct. 6 - 19) 410-280-6127 EXHIBITOR'S LOUNGE The Annapolis Fleet Reserve Club has again made its facilities available to exhibitors at the sailboat and powerboat shows. The Lounge will be open for breakfast, buffet lunch, and bar service during set-up, show days and tear-down of both shows. The Fleet Reserve Club is on Compromise Street between Tent D and the Annapolis Waterfront Hotel.
    [Show full text]
  • 30 by Day, 60 by Night F
    pro*, n, j, Happy annlversaryl. City of Sanibel to celebrate its 20th year Insert Postal Customer •-'-T ?L.-^.IZJZ»ZJ&J«I J Since 1961. Still first on &-:nifoeJ and Captlva islands VOL 33, NO. 44 TUESDAY, NOV. 1, 1994 2 SECTIONS, 36 PAGES 50 CENTS Sunrise over Estero The recent cool, clear mornings have been Ideal for beach walk- ers to watch the col- orful sunrises over Estero Island. Per- haps the best van- tage point is from trie lighthouse end of Sanibel. Photo by Tracey Mariwalter 30 by day, 60 by night Restaurant with varying number of seats OK'd by Planning Commission By Steve Ruediger Sanibel Planning Director Bruce Rogers said it is had agreed not to have carry-out. islander staff writer the first proposal brought before the Planning During the meeting, Sanibel Planning Director A restaurant with 30 seats during the day and 60 Commission in which parking is shared through one Bruce Rogers commented that without carry-out there seats at night was given initial approval by the use, and there has been an agreement that one busi- would be enough parking for 30 people during the Sanibel Planning Commission at its Tuesday, Oct. 25, ness will shut down at a particular time in order for day. meeting. another to use the available parking. The Bailey Hartsell quickly responded that his clients would The restaurant is to be a gourmet dining location Shopping Center PUD is similar in that it assumes agree to drop their request for 42 seats prior to 9:30 with both indoor and outdoor seating in the Forever that the Island Cinema movie theater will use parking a.m.
    [Show full text]
  • Show Guide 7.5X11 FA.Indd 1 2019/08/27 14:03 Kineticcatamarans.Com
    Site Map Exhibitor List Complete Boat List VIP Experience American Sailing Summit Featured Activities Grand Prize OCTOBER 10-14, 2019 SHOW 2019 GUIDE 410.268.8828 | AnnapolisBoatShows.com FOR THE LATEST NEWS FOLLOW US ON FACEBOOK! Official Directory in Cooperation with and a Supplement to: SPECTACULAR “”ALEXANDRIA W. − 5-TIME REPEAT CHARTER GUEST VISIT US AT BOOTH 14 TO TOUR OUR YACHTS AND SAVE UP TO 20% ON YOUR NEXT CHARTER. Maximize Your Boating Dollar! Earn points back on purchases. Visit us at the Annapolis Boat Shows Power Show: October 3–6 in Booths C4 and C6 Sail Show: October 10–14 in Booth Land 20 Shop our nearby locations! Annapolis, MD Chester, MD Edgewater, MD Glen Burnie, MD 113 Hillsmere Dr. 2122 Didonato Dr. 3257 Solomons Isl. Rd. 595 E. Ordnance Rd. S R (410) 268-0129 (410) 604-1752 (410) 956-8920 (443) 572-0814 Y E A westmarine.com MOORINGS.COM/CBM | 800.669.6529 US_TM_5529_1019_AD - Chesapeake Bay Magazine Ad - Annapolis Show Program.indd 1 8/22/19 11:38 AM SPECTACULAR “”ALEXANDRIA W. − 5-TIME REPEAT CHARTER GUEST VISIT US AT BOOTH 14 TO TOUR OUR YACHTS AND SAVE UP TO 20% ON YOUR NEXT CHARTER. Maximize Your Boating Dollar! Earn points back on purchases. Visit us at the Annapolis Boat Shows Power Show: October 3–6 in Booths C4 and C6 Sail Show: October 10–14 in Booth Land 20 Shop our nearby locations! Annapolis, MD Chester, MD Edgewater, MD Glen Burnie, MD 113 Hillsmere Dr. 2122 Didonato Dr. 3257 Solomons Isl. Rd. 595 E.
    [Show full text]
  • Specifications 7 Ft. 8 Ft. 9 Ft. Standard Rowing Model
    Starting with fiberglass lapstrake construction, the Fatty Knees is one of Specifications 7 ft. 8 ft. 9 ft. the strongest dinghies on the water. We chose a hand-laid lapstrake hull, Length 84" 96" 108" Not just for aesthetics, but because it offers considerable strength and stiffness and is relatively lightweight. Her wide beam adds stability and a Beam 48" 51" 54" gentle sheer minimizes its chubby look. Weight (boat only) 90 lbs. 100 lbs. 110 lbs. The inner rail is teak and the outer rail is pressure-treated pine for easy Weight (sail gear) 25 lbs. 28 lbs. 30 lbs. maintenance and durability. The gunwhale guard is long-lasting Dacron® Draft (board up/down) 2"/37" 2"/39" 2"/43" over rubber. The teak rudder and daggerboard are handmade. Sail Areas 40 sq. ft. 50 sq. ft. 60 sq. ft. Whether under sail or as a tender under tow, the boat, with a 7-inch deep skeg, tracks exceptionally well. She’s easy to sail – lively enough in light Boom Clearance 21.5" 24" 25.5" air, tacking and jibing smoothly with virtually no leeway – and most importantly, (required for on safe even in rough weather. Her generous beam makes her less likely to deck storage) flip. Her rigging is simple and with the standard kick-up rudder, you can sail Mast Height 172" 176" 193" right up to the shore. (above water) Every Fatty Knees comes with the mast step, mast partner, daggerboard Centerline 56" 67" 72" trunk and gudgeons installed for easy conversion to sail. of Davit Eyes For those who yearn for a classic, solidly built dinghy that performs well, Top of Transom 19.5" 22.5" 23.5" the Fatty Knees is truly a distinctive little yacht.
    [Show full text]
  • Francesca Cecchinato on Magnesium-Modified Titanium Coatings and Magnesium Alloys for Oral and Orthopaedic Applications: in Vitro Investigation
    FRANCESCACECCHINATO ODONTOLOGY IN DISSERTATION DOCTORAL FRANCESCA CECCHINATO ON MAGNESIUM-MODIFIED TITANIUM COATINGS AND MAGNESIUM ALLOYS FOR ORAL AND ORTHOPAEDIC FOR ORAL AND ORTHOPAEDIC APPLICATIONS: APPLICATIONS: ORTHOPAEDIC AND ORAL FOR ALLOYS MAGNESIUM AND COATINGS TITANIUM MAGNESIUM-MODIFIED ON APPLICATIONS: IN VITRO INVESTIGATION IN VITRO IN INVESTIGATION MALMÖ UNIVERSITY2015 MALMÖ ON MAGNESIUM-MODIFIED TITANIUM COATINGS AND MAGNESIUM ALLOYS FOR ORAL AND ORTHOPAEDIC APPLICATIONS: IN VITRO INVESTIGATION Malmö University Faculty of Odontology Doctoral Dissertations 2015 © Francesca Cecchinato, 2015 Photographs and illustrations: Francesca Cecchinato ISBN 978-91-7104-641-3 (print) ISSN 978-91-7104-642-0 (pdf) Holmbergs, Malmö 2015 FRANCESCA CECCHINATO ON MAGNESIUM-MODIFIED TITANIUM COATINGS AND MAGNESIUM ALLOYS FOR ORAL AND ORTHOPAEDIC APPLICATIONS: IN VITRO INVESTIGATION Malmö University, 2015 Department of Prosthodontics Faculty of Odontology Malmö, Sweden This publication is also available in electronic format at: www.mah.se/muep Dedicated to my father and mother. This thesis is number 47 in a series of investigations on implants, hard tissue, and the Thesis defended 6.2.1995. External examiner: Docent L. Linder. locomotor apparatus originating from the Department of Biomaterials, University of Gothenburg and the Department of Prosthodontics/Material Sciences, Malmö 13. Patricia Campbell BA, 1995. On Aseptic Loosening in Total Hip Replacement: the University, Sweden. Role of UHMWPE Wear Particles. Thesis defended 7.2.1995. External examiner: Professor D. Howie. 1. Anders R Eriksson DDS, 1984. Heat-induced Bone Tissue Injury. An in vivo investigation of heat tolerance of bone tissue and temperature rise in the drilling of 14. Ann Wennerberg, DDS, 1996. On Surface Roughness and Implant Incorporation. cortical bone.
    [Show full text]
  • Latitude 38 September 2013
    Latitude 38 Latitude VOLUME 435 S t b 2013 WE GO WHERE THE WIND BLOWS SEPTEMBER 2013 VOLUME 435 YRA SECOND Everyone needs a midsummer break and sailors are no different. Traditionally scheduled as the first race back after taking the month of July off for 'summer vacation', the YRA’s Second Half Opener is typically one of the Bay’s more popular events. Serving as races four and five of the Party Circuit, the Second Half Opener follows a popular format: After racing from the Berkeley Circle to Point Bonita and back into the Bay, finishing on the Estuary, racers party Saturday night away at Alameda’s beautiful Encinal YC before resuming racing on Sunday with a windward/ leeward race. This combination of a short-distance ocean race No ocean racing this year, but the event should return to regularly scheduled programming next summer. and buoy race are the perfect way to shake off the rust after a month of pool parties, barbecues and trips to Disneyland. Perfect as the format may be, things were a bit different this year. With the America’s Cup activity on the Bay this summer, race organizers and yacht club officials were faced with a major logistical hurdle in planning the Second Half Opener. The normal Bonita race and Sunday buoy race would send the fleet right through the America’s Cup race course, which was advertised to feature multiple AC72s and thousands of spectator FRED FAGO PHOTOS ALL boats. As a result, the race committee was left with no The reworked YRA Second Half Opener drew a greatly reduced fleet, but the on-the-water action was as hot as ever.
    [Show full text]
  • What Works in Conservation
    What Works in Conservation 2015 EDITED BY WILLIAM J. SUTHERLAND, LYNN V. DICKS, NANCY OCKENDON AND REBECCA K. SMITH WHAT WORKS IN CONSERVATION What Works in Conservation 2015 Edited by William J. Sutherland, Lynn V. Dicks, Nancy Ockendon and Rebecca K. Smith http://www.openbookpublishers.com © 2015 William J. Sutherland This work is licensed under a Creative Commons Attribution 4.0 International license (CC BY 4.0). This license allows you to share, copy, distribute and transmit the work; to adapt the work and to make commercial use of the work providing attribution is made to the author (but not in any way that suggests that they endorse you or your use of the work). Attribution should include the following information: Sutherland, W.J., Dicks, L.V., Ockendon, N., and Smith, R.K. What Works in Conservation. Cambridge, UK: Open Book Publishers, 2015. http://dx.doi. org/10.11647/OBP.0060 In order to access detailed and updated information on the license, please visit http://www.openbookpublishers.com/isbn/9781783741571#copyright Further details about CC BY licenses are available at http://creativecommons.org/ licenses/by/4.0/ All links were active at the time of publication unless otherwise stated. Digital material and resources associated with this volume are available at http:// www.openbookpublishers.com/isbn/9781783741571#resources and http://www. conservationevidence.com ISSN 2059-4232 (Print) ISSN 2059-4240 (Online) ISBN Paperback: 978-1-78374-157-1 ISBN Hardback: 978-1-78374-158-8 ISBN Digital (PDF): 978-1-78374-159-5 ISBN Digital ebook (epub): 978-1-78374-160-1 ISBN Digital ebook (mobi): 978-1-78374-161-8 DOI: 10.11647/OBP.0060 Funded by Arcadia, Synchronicity Earth, ESRC, NERC, Natural England and Waitrose Ltd.
    [Show full text]