Publications 2019

1. Aalbersberg EA, de Wit-van der Veen BJ, Versleijen MWJ, Saveur LJ, Valk GD, Tesselaar MET, Stokkel MPM. Influence of lanreotide on uptake of (68)Ga-DOTATATE in patients with neuroendocrine tumours: a prospective intra-patient evaluation. Eur J Nucl Med Mol Imaging 2019; 46:696-703 (Amsterdam UMC & NKI). 2. Aalbersberg EA, Geluk-Jonker MM, Young-Mylvaganan T, de Wit-van der Veen LJ, Stokkel MPM. A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice. J Vis Exp 2019; 146:Apr 17 (NKI). 3. Aalbersberg EA, Huizing DM, Walraven I, de Wit-van der Veen BJ, Kulkarni HR, Singh A, Stokkel MP, Baum RP. Parameters to predict progression free and overall survival after peptide receptor radionuclide therapy: a multivariate analysis in 782 patients. J Nucl Med 2019; 60:1259-65 (NKI). 4. Aalbersberg EA, Rossi MM, de Wit-van der Veen LJ, Walraven I, van den Heuvel MM, Sonke JJ, Belderbos JS, Vogel WV. Pre-hydration in cisplatin-based CCRT: Effects on tumour concentrations and treatment outcome. Radiother Oncol 2019; 134:30-6 (NKI). 5. Aarts BM, Klompenhouwer EG, Dresen RC, Laenen A, Beets-Tan RGH, Punie K, Neven P, Wildiers H, Maleux G. Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival. Breast Cancer Res Treat 2019; 176:597-605 (NKI). 6. Aarts BM, Klompenhouwer EG, Rice SL, Imani F, Baetens T, Bex A, Horenblas S, Kok M, Haanen JBAG, Beets-Tan RGH, Gomez FM. Cryoablation and immunotherapy: an overview of evidence on its synergy. Insights Imaging 2019; 10:53 (12 pp) (NKI). 7. Aarts, CEM, Hiemstra, IH, Béguin, EP, Hoogendijk, AJ, Bouchmal, S, van Houdt, M, Tool, ATJ, Mul, E, Jansen, MH, Janssen, H, van Alphen, FPJ, de Boer, J-P, Zuur, CL, Meijer, AB, van den Berg, TK & Kuijpers, TW . Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair. Blood advances 2019;3:22:3562-3574 (Amsterdam UMC & NKI). 8. Aarts, CEM, Hiemstra, IH, Tool, ATJ, van den Berg, TK, Mul, E, van Bruggen, R & Kuijpers, TW . Neutrophils as Suppressors of T Cell Proliferation: Does Age Matter?. Frontiers in immunology 2019;10:: (Amsterdam UMC). 9. Abis, GSA, Stockmann, HBAC, Bonjer, HJ, van Veenendaal, N, van Doorn-Schepens, MLM, Budding, AE, Wilschut, JA, van Egmond, M, Oosterling, SJ, Abis, GSA, Bonjer, HJ, van Veenendaal, N, van Doorn-Schepens, MLM, Budding, AE, de Lange, ESM, Tuynman, JB, e. Vandenbroucke-Grauls, CMJ, Wilschut, JA, van Egmond, M, C. Stockmann, HBA, van der Bij, GJ, de Korte, N, Oosterling, SJ, Acherman, YIZ, den Boer, FC, Sonneveld, DJA, Poort, L, Abis, GSA, Bonjer, HJ, van Veenendaal, N, van Doorn-Schepens, MLM, Budding, AE, de Lange, ESM, Tuynman, JB, e Vandenbroucke-Grauls, CMJ, Wilschut, JA, van Egmond, M, C Stockmann, HBA, van der Bij, GJ, de Korte, N, Oosterling, SJ & the SELECT trial study group . Randomized clinical trial of selective decontamination of the digestive tract in elective colorectal cancer surgery (SELECT trial). British Journal of Surgery 2019;106:4:355- 363 (Amsterdam UMC). 10. Abrahams, HJG, Gielissen, MFM, Braamse, AMJ, Bleijenberg, G, Buffart, LM & Knoop, H . Graded activity is an important component in cognitive behavioral therapy to reduce severe fatigue: results of a pragmatic crossover trial in cancer survivors. Acta oncologica (Stockholm, Sweden) 2019;58:12:1692-1698 (Amsterdam UMC). 11. Adamopoulos A, Heidebrecht T, Roosendaal J, Touw WG, Phan IQ, Beijnen J, Perrakis A. The domain architecture of protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity. J Biol Chem 2019; 294:12815-25 (NKI). 12. Adamopoulos A, Landskron L, Heidebrecht T, Tsakou F, Bleijerveld OB, Altelaar M, Nieuwenhuis J, Celie PHN, Brummelkamp TR, Perrakis A. Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP. Nat Struct Mol Biol 2019; 26:567-70 (NKI). 13. Adams, HC, Stevenaert, F, Krejcik, J, Van der Borght, K, Smets, T, Bald, J, Abraham, Y, Ceulemans, H, Chiu, C, Vanhoof, G, Usmani, SZ, Plesner, T, Lonial, S, Nijhof, I, Lokhorst, HM, Mutis, T, van de Donk, NWCJ, Sasser, AK & Casneuf, T . High-Parameter Mass Cytometry Evaluation of Relapsed/Refractory Multiple Myeloma Patients Treated with Daratumumab Demonstrates Immune Modulation as a Novel Mechanism of Action. Cytometry Part A 2019;95:3:279-289 (Amsterdam UMC). 14. Adan, F, Crijns, MB, Dekker, E, Bastiaansen, BAJ, Lapid, O, Snaebjornsson, P, Rosenberg, EH, van Leerdam, ME & Bekkenk, MW . A squamous cell carcinoma in a young woman with Lynch syndrome. Familial cancer 2019;18:2:193-196 (Amsterdam UMC & NKI). 15. Admiraal R, de Witte MA, Huitema A, Nierkens S. Pharmacological considerations in antithymocyte globulin exposure calculation. Biol Blood Marrow Transplant 2019; 25:e213-e215 [Letter] (NKI). 16. Ahrends T, Busselaar J, Severson TM, Babala N, de Vries E, Bovens A, Wessels L, van Leeuwen F, Borst J. CD4(+) T cell help creates memory CD8(+) T cells with innate and help-independent recall capacities. Nat Commun 2019; 10:5531 (NKI). 17. Aide et Recherche en Cancerologie Digestive Group, Burzykowski, T, Coart, E, Saad, ED, Shi, Q, Sommeijer, DW, Bokemeyer, C, Díaz-Rubio, E, Douillard, J-Y, Falcone, A, Fuchs, CS, Goldberg, RM, Hecht, JR, Hoff, PM, Hurwitz, H, Kabbinavar, FF, Koopman, M, Maughan, TS, Punt, CJA, Saltz, L, Schmoll, H-J, Seymour, MT, Tebbutt, NC, Tournigand, C, van Cutsem, E, de Gramont, A, Zalcberg, JR & Buyse, M . Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA network open 2019;2:9:e1911750 (Amsterdam UMC). 18. Akbari, P, Huijbers, EJM, Themeli, M, Griffioen, AW & van Beijnum, JR . The tumor vasculature an attractive CAR T cell target in solid tumors. Angiogenesis 2019;22:4:473-475 (Amsterdam UMC). 19. Akdeniz D, Schmidt MK, Seynaeve CM, McCool D, Giardiello D, van den Broek AJ, Hauptmann M, Steyerberg EW, Hooning MJ. Risk factors for metachronous contralateral breast cancer: A systematic review and meta-analysis. Breast 2019; 44:1-14 (NKI). 20. Alberts, AR, Roobol, MJ, Verbeek, JFM, Schoots, IG, Chiu, PK, Osses, DF, Tijsterman, JD, Beerlage, HP, Mannaerts, CK, Schimmöller, L, Albers, P & Arsov, C . Prediction of High-grade Prostate Cancer Following Multiparametric Magnetic Resonance Imaging: Improving the Rotterdam European Randomized Study of Screening for Prostate Cancer Risk Calculators. European urology 2019;75:2:310-318 (Amsterdam UMC). 21. Alberts, L, Wolff, HB, Kastelijn, EA, Lagerwaard, FJ, Hofman, FN, Sharouni, SYE, Schramel, FMNH & Coupe, VMH . Patient-reported Outcomes After the Treatment of Early Stage Non–small-cell Lung Cancer With Stereotactic Body Radiotherapy Compared With Surgery. Clinical Lung Cancer 2019;20:5:370-377 (Amsterdam UMC). 22. Albiges L, Powles T, Staehler M, Bensalah K, Giles RH, Hora M, Kuczyk MA, Lam TB, Ljungberg B, Marconi L, Merseburger AS, Volpe A, bu-Ghanem Y, Dabestani S, Fernandez-Pello S, Hofmann F, Kuusk T, Tahbaz R, Bex A. Updated European Association of Urology Guidelines on Renal Cell Carcinoma: Immune Checkpoint Inhibition Is the New Backbone in First-line Treatment of Metastatic Clear-cell Renal Cell Carcinoma. Eur Urol 2019; 76:151-6 (NKI). 23. Aldelaijan S, Devic S, Papaconstadopoulos P, Bekerat H, Cormack RA, Seuntjens J, Buzurovic IM. Dose response linearization in radiochromic film dosimetry based on multichannel normalized pixel value with an integrated spectral correction for scanner response variations. Med Phys 2019; 46:5336-49 (NKI). 24. Ali M, Foldvari Z, Giannakopoulou E, Boschen ML, Stronen E, Yang W, Toebes M, Schubert B, Kohlbacher O, Schumacher TN, Olweus J. Induction of neoantigen-reactive T cells from healthy donors. Nat Protoc 2019; 14:1926-43 (NKI). 25. Allodji, RS, Hawkins, MM, Bright, CJ, Fidler-Benaoudia, MM, Winter, DL, Alessi, D, Fresneau, B, Journy, N, Morsellino, V, Bárdi, E, Bautz, A, Byrne, J, Feijen, ELAM, Teepen, JC, Vu-Bezin, G, Rubino, C, Garwicz, S, Grabow, D, Gudmundsdottir, T, Guha, J, Hau, E-M, Jankovic, M, Kaatsch, P, Kaiser, M, Linge, H, Muraca, M, Llanas, D, Veres, C, Øfstaas, H, Diallo, I, Mansouri, I, Ronckers, CM, Skinner, R, Terenziani, M, Wesenberg, F, Wiebe, T, Sacerdote, C, Jakab, Z, Haupt, R, Lähteenmäki, PI, Zaletel, LZ, Kuehni, CE, Winther, JF, Michel, G, Kremer, LCM, Hjorth, L, Haddy, N, de Vathaire, F & Reulen, RC . Risk of subsequent primary leukaemias among 69,460 five-year survivors of childhood cancer diagnosed from 1940 to 2008 in Europe: A cohort study within PanCareSurFup. European journal of cancer (Oxford, England 2019;117::71-83 (Amsterdam UMC). 26. Al-Mamgani A, Navran A, Walraven I, Schreuder WH, Tesselaar MET, Klop WMC. Organ-preservation (chemo)radiotherapy for T4 laryngeal and hypopharyngeal cancer: is the effort worth? . Eur Arch Otorhinolaryngol 2019; 276:575-83 (NKI). 27. Almasian, M, Wilk, LS, Bloemen, PR, van Leeuwen, TG, ter Laan, M & Aalders, MCG . Pilot feasibility study of in vivo intraoperative quantitative optical coherence tomography of human brain tissue during glioma resection. Journal of biophotonics 2019 (Amsterdam UMC). 28. Alsaieedi A, Holler A, Velica P, Bendle G, Stauss HJ. Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells. Oncoimmunology 2019; 8:1542917 (NKI). 29. Amant, F, Berveiller, P, Boere, IA, Cardonick, E, Fruscio, R, Fumagalli, M, Halaska, MJ, Hasenburg, A, Johansson, ALV, Lambertini, M, Lok, CAR, Maggen, C, Morice, P, Peccatori, F, Poortmans, P, van Calsteren, K, Vandenbroucke, T, van Gerwen, M, van den Heuvel-Eibrink, M, Zagouri, F & Zapardiel, I . Gynecologic cancers in pregnancy: Guidelines based on a third international consensus meeting. Annals of oncology 2019;30:10:1601-1612 (Amsterdam UMC & NKI). 30. Amaria, RN, Menzies, AM, Burton, EM, Scolyer, RA, Tetzlaff, MT, Antdbacka, R, Ariyan, C, Bassett, R, Carter, B, Daud, A, Faries, M, Fecher, LA, Flaherty, KT, Gershenwald, JE, Hamid, O, Hong, A, Kirkwood, JM, Lo, S, Margolin, K, Messina, J, Postow, MA, Rizos, H, Ross, MI, Rozeman, EA, Saw, RPM, Sondak, V, Sullivan, RJ, Taube, JM, Thompson, JF, van de Wiel, BA, Eggermont, AM, Davies, MA, Andrews, MC, Berry, DA, Block, MS, Boland, GM, Bollin, KB, Carlino, MS, Carvajal, RD, Cohen, J, Davar, D, Delman, KA, Dummer, R, Farwell, MD, Fisher, DE, Fusi, A, Glitza, IC, de Gruijl, TD, Gyorki, DE, Hauschild, A, Hieken, TJ, Larkin, J, Lawson, DH, Lebbe, C, Lee, JE, Lowe, MC, Luke, JJ, McArthur, GA, McDermott, DF, McQuade, JL, Mitchell, TC, Petrella, TM, Prieto, PA, Puzanov, I, Robert, C, Salama, AK, Sandhu, S, Schadendorf, D, Shoushtari, AN, Sosman, JA, Swetter, SM, Tanabe, KK, Turajlic, S, Tyler, DS, Woodman, SE, Wright, FC, Zager, JS, Ascierto, PA, Spillane, AJ, van Akkooi, ACJ, Wargo, JA, Blank, CU, Tawbi, HA & Long, GV . Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium. Lancet Oncology 2019;20:7:e378-e389 (Amsterdam UMC & NKI). 31. Tagliaferri, L, Kovács, G, Aristei, C, de Sanctis, V, Barbera, F, Morganti, AG, Casà, C, Pieters, BR, Russi, E, Livi, L, Corvò, R, Giovagnoni, A, Ricardi, U, Valentini, V & Magrini, SM . Current state of interventional radiotherapy (brachytherapy) education in Italy: Results of the INTERACTS survey. Journal of contemporary brachytherapy 2019;11:1:48-53 (Amsterdam UMC). 32. Angus, L, Smid, M, Wilting, SM, van Riet, J, Van Hoeck, A, Nguyen, L, Nik-Zainal, S, Steenbruggen, TG, Tjan-Heijnen, VCG, Labots, M, van Riel, JMGH, Bloemendal, HJ, Steeghs, N, Lolkema, MP, Voest, EE, van de Werken, HJG, Jager, A, Cuppen, E, Sleijfer, S & Martens, JWM . The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies. Nature Genetics 2019;51:10:1450-1458 (Amsterdam UMC & NKI). 33. Ankersmit, M, Hoekstra, OS, van Lingen, A, Bloemena, E, Jacobs, MAJM, Vugts, DJ, Bonjer, HJ, van Dongen, GAMS & Meijerink, WJHJ . Perioperative PET/CT lymphoscintigraphy and fluorescent real- time imaging for sentinel lymph node mapping in early staged colon cancer. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:7:1495-1505 (Amsterdam UMC). 34. Annunziato S, de Ruiter JR, Henneman L, Brambillasca CS, Lutz C, Vaillant F, Ferrante F, Drenth AP, van der Burg E, Siteur B, van Gerwen B, De Bruijn R, van Miltenburg MH, Huijbers IJ, van de Ven M, Visvader JE, Lindeman GJ, Wessels LFA, Jonkers J. Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer. Nat Commun 2019; 10:397 (NKI). 35. Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, Goldgar D, Hall P, Knoppers BM, Kraft P, La Croix A, Madalensky L, Mavaddat N, Mittman N, Nabi H, Olopade O, Pashayan N, Schmidt M, Shieh Y, Simard J, Stover-Fiscallini A, Tice JA, van 't Veer L, Wenger N, Wolfson M, Yau C, Ziv E. A response to "Personalised medicine and population health: breast and ovarian cancer". Hum Genet 2019; 138:287-9 [Letter] (NKI). 36. Antoniou, SA, Tsokani, S, Mavridis, D, López-Cano, M, Antoniou, GA, Stefanidis, D, Francis, NK, Smart, N, Muysoms, FE, Morales-Conde, S, Bonjer, HJ & Brouwers, MC . Guideline Assessment Project: Filling the GAP in Surgical Guidelines: Quality Improvement Initiative by an International Working Group. Annals of Surgery 2019;269:4:642-651 (Amsterdam UMC). 37. Antoniou, SA, van Veenendaal, N & Bonjer, HJ . Systematic reviews and meta-analyses in minimally invasive surgery. American Journal of Surgery 2019;218:1:232-233 (Amsterdam UMC). 38. Aparicio-Puerta, E, Jáspez, D, Lebrón, R, Koppers-Lalic, D, Marchal, JA & Hackenberg, M . IiqDB. Nucleic Acids Research 2019;47:D1:D113-D120 (Amsterdam UMC). 39. Araghi, SO, Kiefte-de Jong, JC, van Dijk, SC, Swart, KMA, van Laarhoven, HW, van Schoor, NM, de Groot, LCPGM, Lemmens, V, Stricker, BH, Uitterlinden, AG & van der Velde, N . Folic acid and Vitamin B12 supplementation and the risk of cancer: Long-term Follow-up of the B Vitamins for the Prevention of Osteoporotic Fractures (B-PROOF) Trial. Cancer epidemiology, biomarkers & prevention 2019;28:2:275-282 (Amsterdam UMC). 40. Areia, M, Fuccio, L, Hassan, C, Dekker, E, Dias-Pereira, A & Dinis-Ribeiro, MR . Cost-utility analysis of colonoscopy or faecal immunochemical test for population-based organised colorectal cancer screening. United European gastroenterology journal 2019;7:1:105-113 (Amsterdam UMC). 41. Arjona-Sanchez, A, Rodriguez-Ortiz, L, Baratti, D, Schneider, MA, Gutiérrez-Calvo, A, García-Fadrique, A, Tuynman, JB, Cascales-Campos, PA, Martín, VC, Morales, R, Salti, GI, Arteaga, X, Pacheco, D, Alonso-Gomez, J, Yalkin, O, Villarejo-Campos, P, Sanchez-Hidalgo, JM, Casado-Adam, A, Cosano- Alvarez, A, Rufian-Peña, S & Briceño, J . RAS Mutation Decreases Overall Survival After Optimal Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy of Colorectal Peritoneal Metastasis: A Modification Proposal of the Peritoneal Surface Disease Severity Score. Annals of Surgical Oncology 2019;26:8:2595-2604 (Amsterdam UMC). 42. Arteaga de Castro CS, Hoogendam JP, van Kalleveen I, Raaijmakers AJE, Zweemer RP, Verheijen RHM, Luijten PR, Veldhuis WB, Klomp DWJ. Proton MRS of cervical cancer at 7 T. NMR Biomed 2019; 32:e4015 (8 pp) (NKI). 43. Artegiani B, van Voorthuijsen L, Lindeboom RGH, Seinstra D, Heo I, Tapia P, Lopez-Iglesias C, Postrach D, Dayton T, Oka R, Hu H, van Boxtel R, van Es JH, Offerhaus J, Peters PJ, van Rheenen J, Vermeulen M, Clevers H. Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids. Cell Stem Cell 2019; 24:927-43 (NKI). 44. Ascierto PA, Bruzzi P, Eggermont A, Hamid O, Tawbi HA, van Akkooi A, Caraco C, Puzanov I, Perrone F. The great debate at "Melanoma Bridge 2018", Naples, December 1st, 2018. J Transl Med 2019; 17:148 (NKI). 45. Aslam MA, Alemdehy MF, Pritchard CEJ, Song JY, Muhaimin FI, Wijdeven RH, Huijbers IJ, Neefjes J, Jacobs H. Towards an understanding of C9orf82 protein/CAAP1 function. PLoS One 2019; 14:e0210526 (NKI). 46. Atef, Y, Koedam, TW, van Oostendorp, SE, Bonjer, HJ, Wijsmuller, AR & Tuynman, JB . Lateral Pelvic Lymph Node Metastases in Rectal Cancer: A Systematic Review. World Journal of Surgery 2019;43:12:3198-3206 (Amsterdam UMC). 47. Atema, V, van Leeuwen, M, Kieffer, JM, Oldenburg, HSA, van Beurden, M, Gerritsma, MA, Kuenen, MA, Plaisier, PW, Cardozo, AMFL, van Riet, YEA, Heuff, G, Rijna, H, van DerMeij, S, Noorda, EM, Timmers, G-J, Vrouenraets, BC, Bollen, M, van der Veen, H, Bijker, N, Hunter, MS & Aaronson, NK . Efficacy of internet-based cognitive behavioral therapy for treatment-induced menopausal symptoms in breast cancer survivors: Results of a randomized controlled trial. Journal of clinical oncology 2019;37:10:809-822 (Amsterdam UMC & NKI). 48. Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE. CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis. Cancer Cell 2019; 35:603-17 (NKI). 49. Babion, I, De Strooper, LMA, Luttmer, R, Bleeker, MCG, Meijer, CJLM, Heideman, DAM, Wilting, SM & Steenbergen, RDM . Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease. Epigenetics 2019;14:6:558-567 (Amsterdam UMC). 50. Babion, I, Jaspers, A, van Splunter, AP, van der Hoorn, IAE, Wilting, SM & Steenbergen, RDM . miR-9- 5p Exerts a Dual Role in Cervical Cancer and Targets Transcription Factor TWIST1. Cells 2019;9:1: (Amsterdam UMC). 51. Babjuk M, Burger M, Comperat EM, Gontero P, Mostafid AH, Palou J, van Rhijn BWG, Roupret M, Shariat SF, Sylvester R, Zigeuner R, Capoun O, Cohen D, Escrig JLD, Hernandez V, Peyronnet B, Seisen T, Soukup V. European Association of Urology Guidelines on Non-muscle-invasive Bladder Cancer (TaT1 and Carcinoma In Situ) - 2019 Update. Eur Urol 2019; 76:639-57 (NKI). 52. Bach, S, Sluiter, NR, Beagan, J, Mekke, JM, Ket, JCF, van Grieken, NCT, Steenbergen, RDM, Ylstra, B, Kazemier, G & Tuynman, JB . Circulating tumor DNA analysis: clinical implications for colorectal cancer patients. A systematic review. JNCI Cancer Spectrum 2019;3:3: (Amsterdam UMC). 53. Badrick T, Bietenbeck A, Cervinski MA, Katayev A, van Rossum HH, Loh TP. Patient-Based Real-Time Quality Control: Review and Recommendations. Clin Chem 2019; 65:962-71 (NKI). 54. Bahjat, M, de Wilde, G, van Dam, T, Maas, C, Bloedjes, T, Bende, RJ, van Noesel, CJM, Luijks, DM, Eldering, E, Kersten, MJ & Guikema, JEJ . The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors. Cell cycle (Georgetown, Tex.) 2019;18:18:2307-2322 (Amsterdam UMC). 55. Baiocchi GL, Giacopuzzi S, Marrelli D, Reim D, Piessen G, Matos da Costa P, Reynolds JV, Meyer HJ, Morgagni P, Gockel I, Lara Santos L, Jensen LS, Murphy T, Preston SR, Ter Ovanesov M, Fumagalli Romario U, Degiuli M, Kielan W, Monig S, Kolodziejczyk P, Polkowski W, Hardwick R, Pera M, Johansson J, Schneider PM, de Steur WO, Gisbertz SS, Hartgrink H, van Sandick JW, Portolani N, Holscher AH, Botticini M, Roviello F, Mariette C, Allum W, De Manzoni G. International consensus on a complications list after gastrectomy for cancer. Gastric Cancer 2019; 22:172-89 (NKI). 56. Baird RD, van Rossum AG, Oliveira M, Beelen KJ, Gao M, Schrier M, Mandjes IA, Garcia-Corbacho J, Vallier AL, Dougall G, van Werkhoven E, Linossi C, Kumar S, Van Tinteren H, Callari M, Beddowes E, Perez-Garcia J, Rosing H, Platte E, Nederlof PM, Schot M, de Vries Schultink AH, Bernards R, Saura C, Gallagher WM, Cortes J, Caldas C, Linn SC. POSEIDON phase 1b results: safety, efficacy and ctDNA response of taselisib combined with tamoxifen in hormone receptor positive metastatic breast cancer patients. Clin Cancer Res 2019; 25:6598-605 (NKI). 57. Bakhuizen JJ, Hogervorst FB, Velthuizen ME, Ruijs MW, van Engelen K, van Os TA, Gille JJ, Collee M, van den Ouweland AM, van Asperen CJ, Kets CM, Mensenkamp AR, Leter EM, Blok MJ, de Jong MM, Ausems MG. TP53 germline mutation testing in early-onset breast cancer: findings from a nationwide cohort. Fam Cancer 2019; 18:273-80 (NKI). 58. Bakhuizen JJ, Velthuizen ME, Stehouwer S, Bleiker EM, Ausems MG. Genetic counselling of young women with breast cancer for Li-Fraumeni syndrome: a nationwide survey on the experiences and attitudes of genetics professionals. Fam Cancer 2019; 18:231-9 (NKI). 59. Bakhuizen, JJ, Hogervorst, FB, Velthuizen, ME, Ruijs, MW, van Engelen, K, van Os, TA, Gille, JJ, Collée, M, van den Ouweland, AM, van Asperen, CJ, Kets, CM, Mensenkamp, AR, Leter, EM, Blok, MJ, de Jong, MM & Ausems, MG . TP53 germline mutation testing in early-onset breast cancer. Familial Cancer 2019;18:2:273-280 (Amsterdam UMC & NKI). 60. Bakker, A, van der Zee, J, van Tienhoven, G, Kok, HP, Rasch, CRN & Crezee, H . Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review. International journal of hyperthermia 2019;36:1:1024-1039 (Amsterdam UMC). 61. Bakker, MF, de Lange, SV, Pijnappel, RM, Mann, RM, Peeters, PHM, Monninkhof, EM, Emaus, MJ, Loo, CE, Bisschops, RHC, Lobbes, MBI, de Jong, MDF, Duvivier, KM, Veltman, J, Karssemeijer, N, de Koning, HJ, van Diest, PJ, Mali, WPTM, van den Bosch, MAAJ, Veldhuis, WB, van Gils, CH & DENSE Trial Study Group . Supplemental MRI Screening for Women with Extremely Dense Breast Tissue. New England Journal of Medicine 2019;381:22:2091-2102 (Amsterdam UMC & NKI). 62. Balboni, B, el Hassouni, B, Honeywell, RJ, Sarkisjan, D, Giovannetti, E, Poore, J, Heaton, C, Peterson, C, Benaim, E, Lee, YB, Kim, DJ & Peters, GJ . RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment. Expert Opinion on Investigational Drugs 2019;28:4:311-322 (Amsterdam UMC). 63. Baltussen EJM, Brouwer de Koning SG, Sanders J, Aalbers AGJ, Kok NFM, Beets GL, Hendriks BHW, Sterenborg HJCM, Kuhlmann KFD, Ruers TJM. Tissue diagnosis during colorectal cancer surgery using optical sensing: an in vivo study. J Transl Med 2019; 17:333 (NKI). 64. Baltussen, EJM, Brouwer de Koning, SG, Sanders, J, Aalbers, AGJ, Kok, NFM, Beets, GL, Hendriks, BHW, Sterenborg, HJCM, Kuhlmann, KFD & Ruers, TJM . Tissue diagnosis during colorectal cancer surgery using optical sensing: An in vivo study. Journal of translational medicine 2019;17:1: (Amsterdam UMC & NKI). 65. Baltussen, EJM, Kok, END, Brouwer de Koning, SG, Sanders, J, Aalbers, AGJ, Kok, NFM, Beets, GL, Flohil, CC, Bruin, SC, Kuhlmann, KFD, Sterenborg, HJCM & Ruers, TJM . Hyperspectral imaging for tissue classification, a way toward smart laparoscopic colorectal surgery. Journal of biomedical optics 2019;24:1:44075 (Amsterdam UMC & NKI). 66. Baltussen, EJM, Sterenborg, HJCM, Ruers, TJM & Dashtbozorg, B . Optimizing algorithm development for tissue classification in colorectal cancer based on diffuse reflectance spectra. Biomedical optics express 2019;10:12:6096-6113 (Amsterdam UMC & NKI). 67. Bancroft EK, Saya S, Page EC, Myhill K, Thomas S, Pope J, Chamberlain A, Hart R, Glover W, Cook J, Rosario DJ, Helfand BT, Hutten SC, Davidson R, Longmuir M, Eccles DM, Gadea N, Brewer C, Barwell J, Salinas M, Greenhalgh L, Tischkowitz M, Henderson A, Evans DG, Buys SS, Eeles RA, Aaronson NK. Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations. BJU Int 2019; 123:284-92 (NKI). 68. Banerji U, van Herpen CML, Saura C, Thistlethwaite F, Lord S, Moreno V, Macpherson IR, Boni V, Rolfo C, de Vries EGE, Rottey S, Geenen J, Eskens F, Gil-Martin M, Mommers EC, Koper NP, Aftimos P. Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study. Lancet Oncol 2019; 20:1124-35 (NKI). 69. Bansal, D, Davidson, A, Supriyadi, E, Njuguna, F, Ribeiro, RC & Kaspers, GJL . SIOP PODC adapted risk stratification and treatment guidelines. Pediatric Blood and Cancer 2019 (Amsterdam UMC). 70. Baranov, NS, Nagtegaal, ID, van Grieken, NCT, Verhoeven, RHA, Voorham, QJM, Rosman, C & van der Post, RS . Synoptic reporting increases quality of upper gastrointestinal cancer pathology reports. Virchows Archiv 2019;475:2:255-259 (Amsterdam UMC). 71. Barazas M, Gasparini A, Huang Y, Kucukosmanoglu A, Annunziato S, Bouwman P, Sol W, Kersbergen A, Proost N, de Korte-Grimmerink R, van de Ven M, Jonkers J, Borst GR, Rottenberg S. Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors. Cancer Res 2019; 79:452-60 (NKI). 72. Barbé, E, de Boer, M & de Jong, D . A practical cytological approach to the diagnosis of breast- implant associated anaplastic large cell lymphoma. CANCER CYTOPATHOLOGY 2019;30:4:363-369 (Amsterdam UMC). 73. Barbieri, S, Gurney-Champion, OJ, Klaassen, R & Thoeny, HC . Deep learning how to fit an intravoxel incoherent motion model to diffusion-weighted MRI. Magnetic resonance in medicine 2019;83:1:312-321 (Amsterdam UMC). 74. Barco, S, Verly, I, Corrias, MV, Sorrentino, S, Conte, M, Tripodi, G, Tytgat, G, van Kuilenburg, A, van der Ham, M, de Sain-van der Velden, M, Garaventa, A & Cangemi, G . Plasma free metanephrines for diagnosis of neuroblastoma patients. Clinical biochemistry 2019;66::57-62. (Amsterdam UMC). 75. Bar-Ephraim, YE, Koning, JJ, Burniol Ruiz, E, Konijn, T, Mourits, VP, Lakeman, KA, Boon, L, Bögels, M, van Maanen, JP, Den Haan, JMM, van Egmond, M, Bouma, G, Reijmers, RM & Mebius, RE . CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors. Journal of Immunology 2019;202:1:171-182 (Amsterdam UMC). 76. Bartel F, Visser M, de Ruiter M, Belderbos J, Barkhof F, Vrenken H, de Munck JC, van Herk M. Non- linear registration improves statistical power to detect hippocampal atrophy in aging and dementia. Neuroimage Clin 2019; 23:101902 (NKI). 77. Bartel F, Vrenken H, van Herk M, de Ruiter M, Belderbos J, Hulshof J, de Munck JC. FAst Segmentation Through SURface Fairing (FASTSURF): A novel semi-automatic hippocampus segmentation method. PLoS One 2019; 14:e0210641 (NKI). 78. Bartel, F, van Herk, M, Vrenken, H, Vandaele, F, Sunaert, S, de Jaeger, K, Dollekamp, NJ, Carbaat, C, Lamers, E, Dieleman, EMT, Lievens, Y, de Ruysscher, D, Schagen, SB, de Ruiter, MB, de Munck, JC & Belderbos, J . Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation. Clinical and Translational Oncology 2019;21:2:178-186 (Amsterdam UMC & NKI). 79. Bartelink H. Regional nodal irradiation for early breast cancer; clinical benefit according to risk stratification. Breast 2019; 48 Suppl 1:S65-S68 (NKI). 80. Bartels, L, de Jong, G, Gillissen, MA, Yasuda, E, Kattler, V, Bru, C, Fatmawati, C, van Hal-van Veen, SE, Cercel, MG, Moiset, G, Bakker, AQ, van Helden, PM, Villaudy, J, Hazenberg, MD, Spits, H & Wagner, K . A chemo-enzymatically linked bispecific antibody retargets T cells to a sialylated epitope on CD43 in acute myeloid leukemia. Cancer research 2019;79:13:3372-3382 (Amsterdam UMC). 81. Bartels, L, Ploegh, HL, Spits, H & Wagner, K . Preparation of bispecific antibody-protein adducts by site-specific chemo-enzymatic conjugation. Methods (San Diego, Calif.) 2019;154::93-101. (Amsterdam UMC). 82. Barthel, FP, Johnson, KC, Varn, FS, Moskalik, AD, Tanner, G, Kocakavuk, E, Anderson, KJ, Abiola, O, Aldape, K, Alfaro, KD, Alpar, D, Amin, SB, Ashley, DM, Bandopadhayay, P, Barnholtz-Sloan, JS, Beroukhim, R, Bock, C, Brastianos, PK, Brat, DJ, Brodbelt, AR, Bruns, AF, Bulsara, KR, Chakrabarty, A, Chakravarti, A, Chuang, JH, Claus, EB, Cochran, EJ, Connelly, J, Costello, JF, Finocchiaro, G, Fletcher, MN, French, PJ, Gan, HK, Gilbert, MR, Gould, PV, Grimmer, MR, Iavarone, A, Ismail, A, Jenkinson, MD, Khasraw, M, Kim, H, Kouwenhoven, MCM, LaViolette, PS, Li, M, Lichter, P, Ligon, KL, Lowman, AK, Malta, TM, Mazor, T, McDonald, KL, Molinaro, AM, Nam, DH, Nayyar, N, Ng, HK, Ngan, CY, Niclou, SP, Niers, JM, Noushmehr, H, Noorbakhsh, J, Ormond, DR, Park, CK, Poisson, LM, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, JK, Schuster, M, Shaw, BL, Short, SC, Smitt, PAS, Sloan, AE, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, EG, Watts, C, Weller, M, Wesseling, P, Westerman, BA, Widhalm, G, Woehrer, A, Yung, WKA, Zadeh, G, Huse, JT, De Groot, JF, Stead, LF, Verhaak, RGW & The GLASS Consortium . Longitudinal molecular trajectories of diffuse glioma in adults. Nature 2019;576:7785:112-120 (Amsterdam UMC). 83. Bastiaenen, VP, Klaver, CEL, Kok, NFM, de Wilt, JHW, de Hingh, IHJT, Aalbers, AGJ, Boerma, D, Bremers, AJA, Burger, JWA, van Duyn, EB, Evers, P, van Grevenstein, WMU, Hemmer, PHJ, Madsen, EVE, Snaebjornsson, P, Tuynman, JB, Wiezer, MJ, Dijkgraaf, MGW, van der Bilt, JDW & Tanis, PJ . Second and third look laparoscopy in pT4 colon cancer patients for early detection of peritoneal metastases; The COLOPEC 2 randomized multicentre trial. BMC cancer 2019;19:1: (Amsterdam UMC & NKI). 84. Bastida C, Soy D, Ruiz-Esquide V, Sanmarti R, Huitema ADR. Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components. Br J Clin Pharmacol 2019; 85:1710-8 (NKI). 85. Batista da Costa J, Gibb EA, Bivalacqua TJ, Liu Y, Oo HZ, Miyamoto DT, Alshalalfa M, Davicioni E, Wright JL, Dall'Era M, Douglas J, Boormans JL, van der Heijden MS, Wu CL, van Rhijn BW, Gupta S, Grivas P, Mouw KW, Murugan P, Fazli L, Ra S, Konety BR, Seiler R, Daneshmand S, Mian OY, Efstathiou JA, Lotan Y, Black PC. Molecular characterization of neuroendocrine-like bladder cancer. Clin Cancer Res 2019; 25:3908-20 (NKI). 86. Becherer, BE, de Boer, M, Spronk, PER, Bruggink, AH, de Boer, JP, van Leeuwen, FE, Mureau, MAM, van der Hulst, RRJW, de Jong, D & Rakhorst, HA . The Dutch Breast Implant Registry: Registration of Breast Implant-Associated Anaplastic Large Cell Lymphoma-A Proof of Concept. Plastic and reconstructive surgery 2019;143:5:1298-1306 (Amsterdam UMC & NKI). 87. Beck A, Retel VP, Bhairosing PA, van den Brekel M, van Harten WH. Barriers and facilitators of patient access to medical devices in Europe: A systematic literature review. Health Policy 2019; 123:1185-98 (NKI). 88. Beck ACC, Kieffer JM, Retel VP, van Overveld LFJ, Takes RP, van den Brekel MWM, van Harten WH, Stuiver MM. Mapping the EORTC QLQ-C30 and QLQ-H&N35 to the EQ-5D for head and neck cancer: Can disease-specific utilities be obtained? PLoS One 2019; 14:e0226077 . (NKI). 89. Beck ACC, Passchier E, Retel VP, Stuiver MM, van der Molen L, Klop WMC, Navran A, van Harten WH, van den Brekel MWM. Study protocol of a prospective multicenter study comparing (cost- )effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy. BMC Cancer 2019; 19:655 (NKI). 90. Beck ACC, Retel VP, van den Brekel MWM, van Harten WH. Patient access to voice prostheses and heat and moisture exchangers: Factors influencing physician's prescription and reimbursement in eight European countries. Oral Oncol 2019; 91:56-64 (NKI). 91. Beek MA, Gobardhan PD, Klompenhouwer EG, Menke-Pluijmers MB, Steenvoorde P, Merkus JW, Rutten HJ, Voogd AC, Luiten EJ. A patient- and assessor-blinded randomized controlled trial of axillary reverse mapping (ARM) in patients with early breast cancer. Eur J Surg Oncol 2019; 46:59-64 (NKI). 92. Beekhof, R, van Alphen, C, Henneman, AA, Knol, JC, Pham, TV, Rolfs, F, Labots, M, Henneberry, E, le Large, TYS, de Haas, RR, Piersma, SR, Vurchio, V, Bertotti, A, Trusolino, L, Verheul, HMW & Jimenez, CR . INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases. Molecular systems biology 2019;15:4: (Amsterdam UMC). 93. Belderbos RA, Baas P, Berardi R, Cornelissen R, Fennell DA, van Meerbeeck JP, Scherpereel A, Vroman H, Aerts JGJV. A multicenter, randomized, phase II/III study of dendritic cells loaded with allogeneic tumor cell lysate (MesoPher) in subjects with mesothelioma as maintenance therapy after chemotherapy: DENdritic cell Immunotherapy for Mesothelioma (DENIM) trial. Transl Lung Cancer Res 2019; 8:280-5 (NKI). 94. Belghazi, K, Pouw, RE, Koch, AD, Weusten, BLAM, Schoon, EJ, Curvers, WL, Gotink, AW, Mostafavi, N, Haidry, RJ, Pech, O, Bergman, JJGHM & Bisschops, R . Self-sizing radiofrequency ablation balloon for eradication of Barrett's esophagus: results of an international multicenter randomized trial comparing 3 different treatment regimens. Gastrointestinal endoscopy 2019;90:3:415–423 (Amsterdam UMC). 95. Belghazi, K, Schölvinck, DW, van Berge Henegouwen, MI, Gisbertz, SS, Weusten, BL, Meijer, SL, Bergman, JJ & Pouw, RE . Results of a two-phased clinical study evaluating a new multiband mucosectomy device for early Barrett’s neoplasia: a randomized pre-esophagectomy trial and a pilot therapeutic pilot study. Surgical endoscopy 2019;33:9:2864-2872 (Amsterdam UMC). 96. Belkouz, A, Labeur, TA, Dierks, J, Dijk, F, van Oijen, MGH, Verheij, J, van Gulik, TM, van de Vijver, MJ, Wilmink, H, Punt, CJA & Klümpen, H-J . Prognostic immunohistochemical biomarkers of chemotherapy efficacy in biliary tract cancer: A systematic review and meta-analysis. Critical reviews in oncology/hematology 2019;141::82-94. (Amsterdam UMC). 97. Berezowska A, Passchier E, Bleiker E. Evaluating a professional patient navigation intervention in a supportive care setting. Support Care Cancer 2019; 27:3281-90 (NKI). 98. Berger DMS, van Veen MM, Madu MF, van Akkooi ACJ, Vogel WV, Balm AJM, Klop WMC. Parotidectomy in patients with head and neck cutaneous melanoma with cervical lymph node involvement. Head Neck 2019; 41:2264-70 (NKI). 99. Berger DMS, Wassenberg RM, Jozwiak K, van de Wiel BA, Balm AJM, van den Berg JG, Klop WMC. Inter-observer variation in the histopathology reports of head and neck melanoma; a comparison between the seventh and eighth edition of the AJCC staging system. Eur J Surg Oncol 2019; 45:235- 41 (NKI). 100. Berghoff AS, Bellosillo B, Caux C, de Langen A, Mazieres J, Normanno N, Preusser M, Provencio M, Rojo F, Wolf J, Zielinski CC. Immune checkpoint inhibitor treatment in patients with oncogene- addicted non-small cell lung cancer (NSCLC): summary of a multidisciplinary round-table discussion. ESMO Open 2019; 4:e000498 (NKI). 101. Bergom C, Vogel WV. Image Guided Evolution of Nodal Contouring Guidelines in Breast Cancer. Int J Radiat Oncol Biol Phys 2019; 103:592-4 [Editorial] (NKI). 102. Bernard, P, Savard, J, Steindorf, K, Sweegers, MG, Courneya, KS, Newton, RU, Aaronson, NK, Jacobsen, PB, May, AM, Galvao, DA, Chinapaw, MJ, Stuiver, MM, Griffith, KA, Mesters, I, Knoop, H, Goedendorp, MM, Bohus, M, Thorsen, L, Schmidt, ME, Ulrich, CM, Sonke, GS, van Harten, W, Winters-Stone, KM, Velthuis, MJ, Taaffe, DR, van Mechelen, W, Kersten, MJ, Nollet, F, Wenzel, J, Wiskemann, J, Verdonck-de Leeuw, IM, Brug, J & Buffart, LM . Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses. Journal of psychosomatic research 2019;124:: (Amsterdam UMC & NKI). 103. Berndsen, RH, Castrogiovanni, CD, Weiss, A, Rausch, M, Dallinga, MG, Miljkovic-Licina, M, Klaassen, I, Meraldi, P, van Beijnum, JR & Nowak-Sliwinska, P . Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expression. British journal of cancer 2019;121:2:139-149 (Amsterdam UMC). 104. Bernhagen D, Jungbluth V, Quilis NG, Dostalek J, White PB, Jalink K, Timmerman P. Bicyclic RGD Peptides with Exquisite Selectivity for the Integrin alphavbeta3 Receptor Using a "Random Design" Approach. ACS Comb Sci 2019; 21:198-206 (Amsterdam UMC & NKI). 105. Bernier MO, Baysson H, Pearce MS, Moissonnier M, Cardis E, Hauptmann M, Struelens L, Dabin J, Johansen C, Journy N, Laurier D, Blettner M, Le Cornet L, Pokora R, Gradowska P, Meulepas JM, Kjaerheim K, Istad T, Olerud H, Sovik A, Bosch de BM, Thierry-Chef I, Kaijser M, Nordenskjold A, Berrington de GA, Harbron RW, Kesminiene A. Cohort Profile: the EPI-CT study: A European pooled epidemiological study to quantify the risk of radiation-induced cancer from paediatric CT. Int J Epidemiol 2019; 48:379-381g (NKI). 106. Berns A, Ringborg U, Eggermont A, Baumann M, Calvo F, Eggert A, Espina C, Hanahan D, Lacombe D, de Lorenzo F, Oberst S, Philip T, Schuz J, Tabernero J, Celis JE. Towards a Cancer Mission in Horizon Europe. Mol Oncol 2019; 13:2301-4 (NKI). 107. Berns A. Quality-assured research environments for translational cancer research. Mol Oncol 2019; 13:543-8 (NKI). 108. Bertels, L, van der Heijden, S, Hoogsteyns, M, Dekker, E, van Asselt, K, van Weert, H & Knottnerus, B . GPs' perspectives on colorectal cancer screening and their potential influence on FIT-positive patients: An exploratory qualitative study from a Dutch context. BJGP Open 2019;3:1: (Amsterdam UMC). 109. Bertolli E, Franke V, Calsavara VF, de Macedo MP, Pinto CAL, van Houdt WJ, Wouters MWJM, Duprat Neto JP, van Akkooi ACJ. Validation of a Nomogram for Non-sentinel Node Positivity in Melanoma Patients, and Its Clinical Implications: A Brazilian-Dutch Study. Ann Surg Oncol 2019; 26:396-405 (NKI). 110. Best SA, Ding S, Kersbergen A, Dong X, Song JY, Xie Y, Reljic B, Li K, Vince JE, Rathi V, Wright GM, Ritchie ME, Sutherland KD. Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma. Nat Commun 2019; 10:4190 (14 pp) (NKI). 111. Best, MG, in ’t Veld, SGJG, Sol, N & Wurdinger, T . RNA sequencing and swarm intelligence–enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA. Nature Protocols 2019;14:4:1206-1234 (Amsterdam UMC). 112. Beulens, AJW, Brinkman, WM, Porte, PJ, Meijer, RP, van Merriënboer, JJG, van der Poel, HG & Wagner, C . The value of a 1-day multidisciplinary robot surgery training for novice robot surgeons. Journal of Robotic Surgery 2019;13:3:435-447 (Amsterdam UMC & NKI). 113. Beulens, AJW, Brinkman, WM, van der Poel, HG, Vis, AN, van Basten, JP, Meijer, RP, Wijburg, CJ, Hendrikx, AJM, van Merriënboer, JJG & Wagner, C . Linking surgical skills to postoperative outcomes: a Delphi study on the robot-assisted radical prostatectomy. Journal of Robotic Surgery 2019;13:5:675-687 (Amsterdam UMC & NKI). 114. Bex A, Mulders P, Jewett M, Wagstaff J, van Thienen JV, Blank CU, van Velthoven R, Del Pilar Laguna M, Wood L, van Melick HHE, Aarts MJ, Lattouf JB, Powles T, de Jong IJ, Rottey S, Tombal B, Marreaud S, Collette S, Collette L, Haanen J. Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients with Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial. JAMA Oncol 2019; 5:164-70 (NKI). 115. Bex, A, Van Thienen, JV, Schrier, M, Graafland, N, Kuusk, T, Hendricksen, K, Lagerveld, B, Zondervan, P, van Moorselaar, JRA, Blank, C, Wilgenbos, S & Haanen, J . A Phase II, single-arm trial of neoadjuvant axitinib plus avelumab in patients with localized renal cell carcinoma who are at high risk of relapse after nephrectomy (NEOAVAX). Future Oncology 2019;15:19:2203-2209 (Amsterdam UMC & NKI). 116. Bhairosing-Kok D, Groothuizen FS, Fish A, Dharadhar S, Winterwerp HHK, Sixma TK. Sharp kinking of a coiled-coil in MutS allows DNA binding and release. Nucleic Acids Res 2019; 47:8888-98 (NKI). 117. Bhindi B, Abel EJ, Albiges L, Bensalah K, Boorjian SA, Daneshmand S, Karam JA, Mason RJ, Powles T, Bex A. Systematic Review of the Role of Cytoreductive Nephrectomy in the Targeted Therapy Era and Beyond: An Individualized Approach to Metastatic Renal Cell Carcinoma. Eur Urol 2019; 75:111-28 [Review] (NKI). 118. Bin BH, Lee SH, Bhin J, Irie T, Kim S, Seo J, Mishima K, Lee TR, Hwang D, Fukada T, Cho EG. The epithelial zinc transporter ZIP10 epigenetically regulates human epidermal homeostasis by modulating histone acetyltransferase activity. Br J Dermatol 2019; 180:869-80 (NKI). 119. Binkley MS, Brady JL, Hajj C, Chelius M, Chau K, Balogh A, Levis M, Filippi AR, Jones M, Ahmed S, MacManus M, Wirth A, Oguchi M, Vistisen AK, Andraos TY, Ng A, Aleman BMP, Choi SH, Kirova Y, Hardy S, Reinartz G, Eich H, Bratman S, Constine LS, Suh CO, Dabaja B, El-Galaly T, Hodgson D, Ricardi U, Yahalom J, Mikhaeel NG, Hoppe RT. Salvage treatment and survival for relapsed follicular lymphoma following primary radiotherapy: A collaborative study on behalf of ILROG. Int J Radiat Oncol Biol Phys 2019; 104:522-9 (NKI). 120. Bins S, Huitema ADR, Laven P, Bouazzaoui SE, Yu H, van Erp N, van Herpen C, Hamberg P, Gelderblom H, Steeghs N, Sleijfer S, van Schaik RHN, Mathijssen RHJ, Koolen SLW. Impact of CYP3A4*22 on Pazopanib Pharmacokinetics in Cancer Patients. Clin Pharmacokinet 2019; 58:651-8 (NKI). 121. Bisschop, C, Wind, TT, Blank, CU, Koornstra, RHT, Kapiteijn, E, van den Eertwegh, AJM, de Groot, JWB, Jalving, M & Hospers, GAP . Association between Pembrolizumab-related Adverse Events and Treatment Outcome in Advanced Melanoma: Results from the Dutch Expanded Access Program. Journal of Immunotherapy 2019;42:6:208-214 (Amsterdam UMC & NKI). 122. Bisschops, R, Dekker, E, East, JE, Johnson, G, Nunes, PP, Sanders, DS, Dinis-Ribeiro, M & Ponchon, T . European Society of Gastrointestinal Endoscopy (ESGE) curricula development for postgraduate training in advanced endoscopic procedures: Rationale and methodology. Endoscopy 2019;51:10:976-979 (Amsterdam UMC & NKI). 123. Bisschops, R, East, JE, Hassan, C, Hazewinkel, Y, Kamiński, MF, Neumann, H, Pellisé, M, Antonelli, G, Bustamante Balen, M, Coron, E, Cortas, G, Iacucci, M, Yuichi, M, Longcroft-Wheaton, G, Pilonis, N, Puig, I, van Hooft, JE & Dekker, E . Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2019. Endoscopy 2019;51:12:1155-1179 (Amsterdam UMC). 124. Bjørke, ACH, Sweegers, MG, Buffart, LM, Raastad, T, Nygren, P & Berntsen, S . Which exercise prescriptions optimize V�O2max during cancer treatment?—A systematic review and meta-analysis. Scandinavian Journal of Medicine and Science in Sports 2019;29:9:1274-1287 (Amsterdam UMC). 125. Blaauwgeers, H, Damhuis, R, Lissenberg-Witte, B, de Langen, AJ, Senan, S & Thunnissen, E . A population-based study of outcomes in surgically resected T3N0 non-small cell lung cancer in the Netherlands, defined using TNM-7 and TNM-8; justification of changes and an argument to incorporate histology in the staging algorithm?. Journal of Thoracic Oncology 2019;14:3:459-467 (Amsterdam UMC & NKI). 126. Blanas, A, Cornelissen, LAM, Kotsias, M, Horst, J, Vrugt, H, Kalay, H, Spencer, D, Kozak, R & van Vliet, SJ . Transcriptional activation of fucosyltransferase (FUT) genes using the CRISPR-dCas9-VPR technology reveals potent N-glycome alterations in colorectal cancer cells. Glycobiology 2019;29:2:137-150 (Amsterdam UMC). 127. Blanch-Hartigan, D, van Eeden, M, Verdam, MGE, Han, PKJ, Smets, EMA & Hillen, MA . Effects of communication about uncertainty and oncologist gender on the physician-patient relationship. Patient education and counseling 2019;102:9:1613-1620 (Amsterdam UMC). 128. Blank CU, Haining WN, Held W, Hogan PG, Kallies A, Lugli E, Lynn RC, Philip M, Rao A, Restifo NP, Schietinger A, Schumacher TN, Schwartzberg PL, Sharpe AH, Speiser DE, Wherry EJ, Youngblood BA, Zehn D. Defining 'T cell exhaustion'. Nat Rev Immunol 2019; 19:665-74 (NKI). 129. Blankenstein SA, van Akkooi ACJ. Adjuvant systemic therapy in high-risk melanoma. Melanoma Res 2019; 29:358-64 (NKI). 130. Bleijenberg AGC, IJspeert JEG, Carballal S, Pellise M, Jung G, van Herwaarden YJ, Bisseling TM, Nagtegaal ID, van Leerdam ME, Spaander MCW, van Lelyveld N, Bessa X, Rodriguez-Alcalde D, Bastiaansen BAJ, de Klaver W, Bemelman WA, Bujanda L, Koornstra JJ, Rivero L, Rodriguez-Moranta F, Balaguer F, Dekker E. Low Incidence of Advanced Neoplasia in Serrated Polyposis Syndrome After (Sub)total Colectomy: Results of a 5-Year International Prospective Cohort Study. Am J Gastroenterol 2019; 114:1512-9 (NKI). 131. Bleijenberg, A, Klotz, D, Loberg, M, Dekker, E, Adami, HO, Kuipers, EJ, Holme, O, Kalager, M, Emilsson, L, Kleist, B, Lovdal, L, Regula, J, Loberg, EM, Ijspeert, J & Bretthauer, M . Implications of different guidelines for surveillance after serrated polyp resection in United States of America and Europe. Endoscopy 2019;51:8:750-758 (Amsterdam UMC). 132. Bleijenberg, AGC, IJspeert, JEG, Carballal, S, Pellise, M, Jung, G, van Herwaarden, YJ, Bisseling, TM, Nagtegaal, ID, van Leerdam, ME, Spaander, MCW, van Lelyveld, N, Bessa, X, Rodríguez-Alcalde, D, Bastiaansen, BAJ, de Klaver, W, Bemelman, WA, Bujanda, L, Koornstra, JJ, Rivero, L, Rodríguez- Moranta, F, Balaguer, F & Dekker, E . Low Incidence of Advanced Neoplasia in Serrated Polyposis Syndrome After (Sub)total Colectomy: Results of a 5-Year International Prospective Cohort Study. American journal of gastroenterology 2019;114:9:1512-1519 (Amsterdam UMC & NKI). 133. Blijlevens, M, van der Meulen-Muileman, IH, de Menezes, RX, Smit, EF & van Beusechem, VW . High- throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome. Oncogene 2019;38:21:4142-4153 (Amsterdam UMC & NKI). 134. Blok JM, Kerst JM, Vegt E, Brouwer OR, Meijer RP, Bosch JLHR, Bex A, van der Poel HG, Horenblas S. Sentinel Node Biopsy in Clinical Stage I Testicular Cancer Enables Early Detection of Occult Metastatic Disease. BJU Int 2019; 124:424-30 (NKI). 135. Blok, RD, de Jonge, J, de Koning, MA, van de Ven, AWH, van der Bilt, JDW, van Geloven, AAW, Hompes, R, Bemelman, WA & Tanis, PJ . Propensity Score Adjusted Comparison of Pelviperineal Morbidity with and Without Omentoplasty Following Abdominoperineal Resection for Primary Rectal Cancer. Diseases of the colon and rectum 2019;62:8:952-959 (Amsterdam UMC). 136. Blok, RD, Hagemans, JAW, Burger, JWA, Rothbarth, J, van der Bilt, JDW, Lapid, O, Hompes, R & Tanis, PJ . Feasibility of a subcutaneous gluteal turnover flap without donor site scar for perineal closure after abdominoperineal resection for rectal cancer. Techniques in coloproctology 2019;23:8:751-759 (Amsterdam UMC). 137. Blom, B, van Hoeven, V & Hazenberg, MD . ILCs in hematologic malignancies: Tumor cell killers and tissue healers. Seminars in immunology 2019;41::101279. (Amsterdam UMC). 138. Blommaert, J, Schroyen, G, Vandenbulcke, M, Radwan, A, Smeets, A, Peeters, R, Sleurs, C, Neven, P, Wildiers, H, Amant, F, Sunaert, S & Deprez, S . Age-dependent brain volume and neuropsychological changes after chemotherapy in breast cancer patients. Human brain mapping 2019;40:17:4994-5010 (Amsterdam UMC). 139. Blommaert, J, Zink, R, Deprez, S, Myatchin, I, Dupont, P, Vandenbroucke, T, Sleurs, C, van Calsteren, K, Amant, F & Lagae, L . Long-term impact of prenatal exposure to chemotherapy on executive functioning: An ERP study. Clinical neurophysiology 2019;130:9:1655-1664 (Amsterdam UMC). 140. Blommestein, HM, van Beurden-Tan, CHY, Franken, MG, Uyl-de Groot, CA, Sonneveld, P & Zweegman, S . Efficacy of first-line treatments for multiple myeloma patients not eligible for stem cell transplantation - A Network Meta-analysis. Haematologica 2019;104:5:1026-1035 (Amsterdam UMC). 141. Blümcke, I, Coras, R, Wefers, AK, Capper, D, Aronica, E, Becker, A, Honavar, M, Stone, TJ, Jacques, TS, Miyata, H, Mühlebner, A, Pimentel, J, Söylemezoğlu, F & Thom, M . Review: Challenges in the histopathological classification of ganglioglioma and DNT: microscopic agreement studies and a preliminary genotype-phenotype analysis. Neuropathology and Applied Neurobiology 2019;45:2:95- 107 (Amsterdam UMC). 142. Bodalal Z, Trebeschi S, Nguyen-Kim TDL, Schats W, Beets-Tan R. Radiogenomics: bridging imaging and genomics. Abdom Radiol (NY) 2019; 44:1960-84 (NKI). 143. Boellaard, R, Sera, T, Kaalep, A, Hoekstra, OS, Barrington, SF & Zijlstra, JM . Updating PET/CT performance standards and PET/CT interpretation criteria should go hand in hand. EJNMMI Research 2019;9:1: (Amsterdam UMC). 144. Boevé, LMS & Vis, AN . Reply to Herney Andrés García-Perdomo's Letter to the Editor re: Liselotte M.S. Boevé, Maarten C.C.M. Hulshof, André N. Vis, et al. Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial. Eur Urol. 2019;75:410–8. High-volume Disease Has a Different Standard of Care: Is Local Treatment Really Beneficial in Low-volume Metastatic Prostate Cancer?. European Urology 2019;75:4:e101-e102 (Amsterdam UMC). 145. Boevé, LMS, Hulshof, MCCM, Vis, AN, Zwinderman, AH, Twisk, JWR, Witjes, WPJ, Delaere, KPJ, Moorselaar, RJAV, Verhagen, PCMS & van Andel, G . Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial. European urology 2019;75:3:410-418 (Amsterdam UMC). 146. Boevé, LMS, Verhagen, PCMS & Vis, AN . Reply to Ashwin Shinde, Richard Li, Arya Amini, and Scott Glaser's Letter to the Editor re: Liselotte M.S. Boevé Maarten C.C.M. Hulshof, André N. Vis, et al. Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial. Eur Urol 2019;75:410–8: Future Steps for Definitive Therapy in Metastatic Prostate Cancer: Lessons from the HORRAD Trial Until Randomised Controlled Trials Prove Different, Treat the Patient, Not His Imaging Results. European Urology 2019;75:3:e71-e72 (Amsterdam UMC). 147. Bohoudi, O, Bruynzeel, AME, Meijerink, MR, Senan, S, Slotman, BJ, Palacios, MA & Lagerwaard, FJ . Identification of patients with locally advanced pancreatic cancer benefitting from plan adaptation in MR-guided radiation therapy. Radiotherapy and Oncology 2019;132::16-22. (Amsterdam UMC). 148. Bohoudi, O, Lagerwaard, FJ, Bruynzeel, AME, Niebuhr, NI, Johnen, W, Senan, S, Slotman, BJ, Pfaffenberger, A & Palacios, MA . End-to-end empirical validation of dose accumulation in MRI- guided adaptive radiotherapy for prostate cancer using an anthropomorphic deformable pelvis phantom. Radiotherapy and Oncology 2019;141::200-207. (Amsterdam UMC). 149. Boire A, Brandsma D, Brastianos PK, Le Rhun E, Ahluwalia M, Junk L, Glantz M, Groves MD, Lee EQ, Lin N, Raizer J, Ruda R, Weller M, van den Bent MJ, Vogelbaum MA, Chang S, Wen PY, Soffietti R. Liquid biopsy in Central Nervous System metastases: a RANO review and proposals for clinical applications. Neuro Oncol 2019; 21:571-84 (NKI). 150. Bongaarts, A, van Scheppingen, J, Korotkov, A, Mijnsbergen, C, Anink, JJ, Jansen, FE, Spliet, WGM, den Dunnen, WFA, Gruber, VE, Scholl, T, Samueli, S, Hainfellner, JA, Feucht, M, Kotulska, K, Jozwiak, S, Grajkowska, W, Buccoliero, AM, Caporalini, C, Giordano, F, Genitori, L, Coras, R, Blümcke, I, Krsek, P, Zamecnik, J, Meijer, L, Scicluna, BP, Schouten-van Meeteren, AYN, Mühlebner, A, Mills, JD & Aronica, E . The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas. Brain 2019;143:1:131-149 (Amsterdam UMC). 151. Bood, ZM, Scherer-Rath, M, Sprangers, MAG, Timmermans, L, van Wolde, E, Cristancho, SM, Heyning, F, Russel, S, van Laarhoven, HWM & Helmich, E . Living with advanced cancer: Rich Pictures as a means for health care providers to explore the experiences of advanced cancer patients. Cancer medicine 2019;8:11:4957-4966 (Amsterdam UMC). 152. Boogerd LSF, Boonstra MC, Prevoo HAJM, Handgraaf HJM, Kuppen PJK, van de Velde CJH, Fish A, Cordfunke RA, Valentijn ARPM, Terwisscha van Scheltinga AG, MacDonald GC, Cizeau J, Premsukh A, Vinkenburg van Slooten ML, Burggraaf J, Sier CFM, Vahrmeijer AL. Fluorescence-guided tumor detection with a novel anti-EpCAM targeted antibody fragment: Preclinical validation. Surg Oncol 2019; 28:1-8 (NKI). 153. Boons, CCLM, Timmers, L, Janssen, JJWM, Swart, EL, Hugtenburg, JG & Hendrikse, NH . Feasibility of and patients’ perspective on nilotinib dried blood spot self-sampling. European Journal of Clinical Pharmacology 2019;75:6:825-829 (Amsterdam UMC). 154. Boons, CCLM, Timmers, L, Westerweel, P, Swart, E, Hendrikse, H & Hugtenburg, J . Response and adherence to Nilotinib in daily practice (RAND-study): An in-depth observational study of patients with chronic myeloid leukemia treated with Nilotinib. Pharmacoepidemiology and Drug Safety 2019;28::125-126. (Amsterdam UMC). 155. Boons, CCLM, Tromp, VNMF, Neppelenbroek, NJM, Timmers, L, van Schoor, NM, Swart, EL, Hendrikse, NH, Janssen, JJWM & Hugtenburg, JG . Satisfaction with information on nilotinib treatment in chronic myeloid leukemia patients. Acta Oncologica 2019;58:6:891-896 (Amsterdam UMC). 156. Boonstra PA, Steeghs N, Farag S, van Coevorden F, Gelderblom H, Grunhagen DJ, Desar IME, van der Graaf WTA, Bonenkamp JJ, Reyners AKL, van Etten B. Surgical and medical management of small bowel gastrointestinal stromal tumors: A report of the Dutch GIST registry. Eur J Surg Oncol 2019; 45:410-5 (NKI). 157. Boonstra, A, Gielissen, M, van Dulmen-den Broeder, E, Blijlevens, N, Knoop, H & Loonen, J . Cognitive Behavior Therapy for Persistent Severe Fatigue in Childhood Cancer Survivors: A Pilot Study. Journal of pediatric hematology/oncology 2019;41:4:313-318 (Amsterdam UMC). 158. Boot J, Gomez-Munoz F, Beets-Tan RGH. [Imaging of rectal cancer. German version](Amsterdam UMC & NKI). 159. Borggreve, AS, Goense, L, Brenkman, HJF, Mook, S, Meijer, GJ, Wessels, FJ, Verheij, M, Jansen, EPM, van Hillegersberg, R, van Rossum, PSN & Ruurda, JP . Imaging strategies in the management of gastric cancer: Current role and future potential of MRI. British Journal of Radiology 2019;92:1097: (Amsterdam UMC & NKI). 160. Bornes L, van Scheppingen RH, Beerling E, Schelfhorst T, Ellenbroek SIJ, Seinstra D, van Rheenen J. Fsp1-Mediated Lineage Tracing Fails to Detect the Majority of Disseminating Cells Undergoing EMT. Cell Rep 2019; 29:2565-9 (NKI). 161. Borst P, Varadi A, van de Wetering K. PXE, a Mysterious Inborn Error Clarified. Trends Biochem Sci 2019; 44:125-40 (NKI). 162. Bosch, LJW, Melotte, V, Mongera, S, Daenen, KLJ, Coupé, VMH, van Turenhout, ST, Stoop, EM, de Wijkerslooth, TR, Mulder, CJJ, Rausch, C, Kuipers, EJ, Dekker, E, Domanico, MJ, Lidgard, GP, Berger, BM, van Engeland, M, Carvalho, B & Meijer, GA . Multitarget Stool DNA Test Performance in an Average-Risk Colorectal Cancer Screening Population. American journal of gastroenterology 2019;114:12:1909-1918 (Amsterdam UMC & NKI). 163. Bosch, S, Berkhout, DJ, Ben Larbi, I, de Meij, TG & de Boer, NK . Fecal volatile organic compounds for early detection of colorectal cancer: where are we now?. Journal of Cancer Research and Clinical Oncology 2019;145:1:223-234 (Amsterdam UMC). 164. Bosch, SL, Verhoeven, RHA, Lemmens, VEPP, Simmer, F, Poortmans, P, de Wilt, JHW & Nagtegaal, ID . Type of preoperative therapy and stage-specific survival after surgery for rectal cancer: a nationwide population-based cohort study. Virchows Archiv 2019;475:6:745-755 (Amsterdam UMC). 165. Bosio M, Drechsel O, Rahman R, Muyas F, Rabionet R, Bezdan D, Domenech Salgado L, Hor HG, Schott JJ, Munell F, Colobran R, Macaya A, Estivill X, Ossowski S. eDiVA - Classification and Prioritization of Pathogenic Variants for Clinical Diagnostics. Hum Mutat 2019; 40:865-78 (NKI). 166. Bosschieter, J, Hentschel, AE, Savci-Heijink, CD, van der Voorn, JP, Rozendaal, RL, Vis, AN, Zwartkruis, ECH, Lissenberg-Witte, BI, van Moorselaar, RJA & Nieuwenhuijzen, JA . Objectifying grade in Ta-T1 urothelial carcinomas of the bladder using proliferative and quantitative markers: A multicentre study in 310 bladder tumors. Urologic Oncology 2019;37:8:530 (Amsterdam UMC). 167. Bosschieter, J, Nieuwenhuijzen, JA, Hentschel, AE, Vis, AN, Lissenberg-Witte, BI, den Otter, W & van Moorselaar, RJA . Value of a Marker Lesion in Non-Muscle-Invasive Bladder Cancer Patients Treated with Interleukin-2 Instillations: A Randomized Controlled Multicentre Trial.. Urologia Internationalis 2019;102:1:69-76 (Amsterdam UMC & NKI). 168. Bosschieter, J, van Moorselaar, RJA & Nieuwenhuijzen, JA . An immediate, single instillation of mitomycin C in non-muscle invasive bladder cancer: Can we define which patients do and do not benefit?. Translational Andrology and Urology 2019;8::S346-S347. (Amsterdam UMC). 169. Botman, R, Tetar, SU, Palacios, MA, Slotman, BJ, Lagerwaard, FJ & Bruynzeel, AME . The clinical introduction of MR-guided radiation therapy from a RTT perspective. Clinical and Translational Radiation Oncology 2019;18::140-145. (Amsterdam UMC). 170. Böttger, F, Schaaij-Visser, TB, de Reus, I, Piersma, SR, Pham, TV, Nagel, R, Brakenhoff, RH, Thunnissen, E, Smit, EF & Jimenez, CR . Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction. Journal of Proteomics 2019;196::106-119. (Amsterdam UMC & NKI). 171. Böttger, F, Semenova, EA, Song, J-Y, Ferone, G, van der Vliet, J, Cozijnsen, M, Bhaskaran, R, Bombardelli, L, Piersma, SR, Pham, TV, Jimenez, CR & Berns, A . Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer. Cell Reports 2019;27:11:3345-3358 (Amsterdam UMC & NKI). 172. Bousema, JE, van Dorp, M, Hoeijmakers, F, Huijbregts, IA, Barlo, NP, Bootsma, GP, van Boven, WP, Claessens, NJM, Dingemans, A-MC, Hanselaar, WE, Kortekaas, RTJ, Lardenoije, J-WHP, Maessen, JG, Schreurs, WH, Vissers, Y, Youssef-el Soud, M, Dijkgraaf, MGW, Annema, J & van den Broek, FJC . Guideline adherence of mediastinal staging of non-small cell lung cancer: A multicentre retrospective analysis. Lung cancer (Amsterdam, Netherlands) 2019;134::52-58. (Amsterdam UMC). 173. Bousema, JE, van Dorp, M, Noyez, VJJM, Dijkgraaf, MGW, Annema, JT & van den Broek, FJC . Unforeseen N2 Disease after Negative Endosconography Findings with or without Confirmatory Mediastinoscopy in Resectable Non–Small Cell Lung Cancer: A Systematic Review and Meta-Analysis. Journal of thoracic oncology 2019;14:6:979-992 (Amsterdam UMC). 174. Bouter, A, Alderliesten, T, Pieters, BR, Bel, A, Niatsetski, Y & Bosman, PAN . GPU-accelerated bi- objective treatment planning for prostate high-dose-rate brachytherapy. Medical physics 2019;46:9:3776-3787 (Amsterdam UMC). 175. Braal CL, Beijnen JH, Koolen SLW, Oomen-de HE, Steeghs N, Jager A, Huitema ADR, Mathijssen RHJ. Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence. J Clin Oncol 2019; 37:1980-1 [Letter] (NKI). 176. Braccioli L, de Wit E. CTCF: a Swiss-army knife for genome organization and transcription regulation. Essays Biochem 2019; 63:157-65 (NKI). 177. Brady JL, Binkley MS, Hajj C, Chelius M, Chau K, Balogh A, Levis M, Filippi AR, Jones M, Mac MM, Wirth A, Oguchi M, Krog VA, Andraos TY, Ng AK, Aleman BMP, Choi SH, Kirova Y, Hardy S, Reinartz G, Eich HT, Bratman SV, Constine LS, Suh CO, Dabaja B, El-Galaly TC, Hodgson DC, Ricardi U, Yahalom J, Hoppe RT, Mikhaeel NG. Definitive radiotherapy for localized follicular lymphoma staged by (18)F- FDG PET-CT: a collaborative study by ILROG. Blood 2019; 133:237-45 (NKI). 178. Bredart A, Kop JL, Antoniou AC, Cunningham AP, de Pauw A, Tischkowitz M, Ehrencrona H, Schmidt MK, Dolbeault S, Rhiem K, Easton DF, Devilee P, Stoppa-Lyonnet D, Schmutlzer R. Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey. J Community Genet 2019; 10:61-71 (NKI). 179. Breedveld, A & van Egmond, M . IgA and FcαRI: Pathological Roles and Therapeutic Opportunities. Frontiers in Immunology 2019;10:: (Amsterdam UMC). 180. Brennan-Jones, CG, McMahen, C & van Dalen, EC . Cochrane corner: platinum-induced hearing loss after treatment for childhood cancer. International journal of audiology 2019;58:4:181-184 (Amsterdam UMC). 181. Bril SI, Pezier TF, Tijink BM, Janssen LM, Braunius WW, De Bree R. Preoperative low skeletal muscle mass as a risk factor for pharyngocutaneous fistula and decreased overall survival in patients undergoing total laryngectomy. Head Neck 2019; 41:1745-55 (NKI). 182. Bringhen, S, Milan, A, D. Prevention, monitoring and treatment of cardiovascular adverse events in myeloma patients receiving carfilzomib A consensus paper by the European Myeloma Network and the Italian Society of Arterial Hypertension. Journal of Internal Medicine 2019;286:1:63-74 (Amsterdam UMC). 183. Brinkman EK, van Steensel B. Rapid Quantitative Evaluation of CRISPR Genome Editing by TIDE and TIDER. Methods Mol Biol 2019; 1961:29-44 (NKI). 184. Brinkman RJ, Hage JJ, Oostra RJ, van der Horst CM. Andreas Vesalius (1515-1564) on animal cognition. Psychon Bull Rev 2019; 26:1588-95 (NKI). 185. Brinkman-Stoppelenburg, A, Polinder, S, Meerum-Terwogt, J, de Nijs, E, van der Padt-Pruijsten, A, Peters, L, van der Vorst, M, van Zuylen, L, Lingsma, H & van der Heide, A . The COMPASS study: A descriptive study on the characteristics of palliative care team consultation for cancer patients in hospitals. European Journal of Cancer Care 2019 (Amsterdam UMC). 186. Brinkman-Stoppelenburg, A, Polinder, S, Olij, BF, van den Berg, B, Gunnink, N, Hendriks, MP, van der Linden, YM, Nieboer, D, van der Padt-Pruijsten, A, Peters, LA, Roggeveen, B, Terheggen, F, Verhage, S, van der Vorst, MJ, Willemen, I, Vergouwe, Y & van der Heide, A . The association between palliative care team consultation and hospital costs for patients with advanced cancer: An observational study in 12 Dutch hospitals. European Journal of Cancer Care 2019 (Amsterdam UMC). 187. Broertjes J, Klarenbeek J, Habani Y, Langeslag M, Jalink K. TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx. PLoS One 2019; 14:e0209563 (NKI). 188. Bromberg JEC, Issa S, Bakunina K, Minnema MC, Seute T, Durian M, Cull G, Schouten HC, Stevens WBC, Zijlstra JM, Baars JW, Nijland M, Mason KD, Beeker A, van den Bent MJ, Beijert M, Gonzales M, de Jong D, Doorduijn JK . Rituximab in patients with primary CNS lymphoma (HOVON 105/ALLG NHL 24): a randomised, open-label, phase 3 intergroup study. Lancet Oncol 2019; 20:216-28 (Amsterdam UMC & NKI). 189. Bronzwaer MES, Depla ACTM, van Lelyveld N, Spanier MBW, Oosterhout YH, van Leerdam ME, Spaander MCW, Dekker E, van Haastert M, Keller JJ, Koch AD, Koornstra JJ, van Kouwen MCA, Masclee A, Mundt MW, de Ridder RJ, van der Sluys-Veer A, van Wieren M. Quality assurance of colonoscopy within the Dutch national colorectal cancer screening program. Gastrointest Endosc 2019; 89:1-13 (NKI). 190. Brouwer de Koning SG, Karakullukcu MB, Lange CAH, Ruers TJM. The oral cavity tumor thickness: Measurement accuracy and consequences for tumor staging. Eur J Surg Oncol 2019; 45:2131-6 (NKI). 191. Brouwer I, Lenstra TL. Visualizing transcription: key to understanding gene expression dynamics. Curr Opin Chem Biol 2019; 51:122-9 (NKI). 192. Brown PJ, Rossington H, Taylor J, Lambregts DMJ, Morris E, West NP, Quirke P, Tolan D. Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice. Eur Radiol 2019; 29:5121-8 (NKI). 193. Brown PJ, Rossington H, Taylor J, Lambregts DMJ, Morris EJA, West NP, Quirke P, Tolan D. Radiologist and multidisciplinary team clinician opinions on the quality of MRI rectal cancer staging reports: how are we doing? Clin Radiol 2019; 74:637-42 . (NKI). 194. Bruin MAC, de Vries N, Lucas L, Rosing H, Huitema ADR, Beijnen JH. Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1138:121925 (NKI). 195. Bruin MAC, Rosing H, Lucas L, Wang J, Huitema ADR, Schinkel AH, Beijnen JH. Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1125:121723 (NKI). 196. Brummer C, Faerber S, Bruss C, Blank C, Lacroix R, Haferkamp S, Herr W, Kreutz M, Renner K. Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma. Cancer Lett 2019; 442:453-63 (NKI). 197. Bruns, ERJ, Argillander, TE, Schuijt, HJ, van Duijvendijk, P, van der Zaag, ES, Wassenaar, EB, Gerhards, MF, Consten, EC, Buskens, CJ, van Munster, BC & Bemelman, WA . Fit4SurgeryTV At-home Prehabilitation for Frail Older Patients Planned for Colorectal Cancer Surgery: A Pilot Study. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists 2019;98:5:399-406 (Amsterdam UMC). 198. Bruns, ERJ, Borstlap, WA, van Duijvendijk, P, van der Zaag-Loonen, HJ, Buskens, CJ, van Munster, BC, Bemelman, WA & Tanis, PJ . The Association of Preoperative Anemia and the Postoperative Course and Oncological Outcome in Patients Undergoing Rectal Cancer Surgery: A Multicenter Snapshot Study. Diseases of the colon and rectum 2019;62:7:823-831 (Amsterdam UMC). 199. Bruns, ERJ, van Rooijen, SJ, Argillander, TE, van der Zaag, ES, van Grevenstein, WMU, van Duijvendijk, P, Buskens, CJ, Bemelman, WA, van Munster, BC, Slooter, GD & van den Heuvel, B . Improving Outcomes in Oncological Colorectal Surgery by Prehabilitation. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists 2019;98:3:231-238 (Amsterdam UMC). 200. Bruynzeel, AME & Lagerwaard, FJ . The role of biological dose-escalation for pancreatic cancer. Clinical and Translational Radiation Oncology 2019;18::128-130. (Amsterdam UMC). 201. Bruynzeel, AME, Tetar, SU, Oei, SS, Senan, S, Haasbeek, CJA, Spoelstra, FOB, Piet, AHM, Meijnen, P, Bakker van der Jagt, MAB, Fraikin, T, Slotman, BJ, van Moorselaar, RJA & Lagerwaard, FJ . A Prospective Single-Arm Phase 2 Study of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy for Prostate Cancer. International Journal of Radiation Oncology Biology Physics 2019;105:5:1086-1094 (Amsterdam UMC). 202. Buccisano, F, Maurillo, L, Schuurhuis, GJ, del Principe, MI, di Veroli, A, Gurnari, C & Venditti, A . The emerging role of measurable residual disease detection in AML in morphologic remission. Seminars in Hematology 2019;56:2:125-130 (Amsterdam UMC). 203. Buijs M, Zondervan PJ, de Bruin DM, van Lienden KP, Bex A, van Delden OM. Feasibility and safety of irreversible electroporation (IRE) in patients with small renal masses: Results of a prospective study. Urol Oncol 2019; 37:183(Amsterdam UMC & NKI). 204. Buikhuisen WA, Qayyum F, Armato SG, III, Baas P. Optimization of response classification criteria for patients with malignant pleural mesothelioma, a validation study. Lung Cancer 2019; 138:139-40 [Letter] (NKI). 205. Buisman FE, Grunhagen DJ, Homs MYV, Grootscholten C, Filipe WF, Kemeny NE, Cercek A, D'Angelica MI, Donswijk ML, van Doorn L, Emmering J, Jarnagin WR, Kingham TP, Klompenhouwer EG, Kok NFM, Kuiper MC, Moelker A, Prevoo W, Versleijen MWJ, Verhoef C, Kuhlmann KFD, Groot Koerkamp B. Adjuvant Hepatic Arterial Infusion Pump Chemotherapy After Resection of Colorectal Liver Metastases: Results of a Safety and Feasibility Study in The Netherlands. Ann Surg Oncol 2019; 26:4599-607 (NKI). 206. Buisman FE, Homs MYV, Grunhagen DJ, Filipe WF, Bennink RJ, Besselink MGH, Borel R, I, Bruijnen RCG, Cercek A, D'Angelica MI, van Delden OM, Donswijk ML, van Doorn L, Doornebosch PG, Emmering J, Erdmann JI, IJzerman NS, Grootscholten C, Hagendoorn J, Kemeny NE, Kingham TP, Klompenhouwer EG, Kok NFM, Koolen S, Kuhlmann KFD, Kuiper MC, Lam MGE, Mathijssen RHJ, Moelker A, Oomen-de Hoop E, Punt CJA, Te Riele WW, Roodhart JML, Swijnenburg RJ, Prevoo W, Tanis PJ, Vermaas M, Versleijen MWJ, Veuger FP, Weterman MJ, Verhoef C, Groot Koerkamp B. Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases - the multicenter randomized controlled PUMP trial. BMC Cancer 2019; 19:327 (Amsterdam UMC & NKI). 207. Buiting HM, van Ark MAC, Dethmers O, Maats EPE, Stoker JA, Sonke GS. Complex challenges for patients with protracted incurable cancer: an ethnographic study in a comprehensive cancer centre in the Netherlands. BMJ Open 2019; 9:e024450 (NKI). 208. Bult, MK, van Bindsbergen, KLA, Schepers, SA, de Ridder-Sluiter, HG, Verhaak, CM, van Litsenburg, RRL, Merks, JHM, van Noesel, MM & Grootenhuis, MA . Health-related quality of life of adolescents with cancer during the first year of treatment. Journal of adolescent and young adult oncology 2019;8:5:616-622 (Amsterdam UMC). 209. Bulten, BF, Sollini, M, Boni, R, Massri, K, de Geus-Oei, L-F, van Laarhoven, HWM, Slart, RHJA & Erba, PA . Cardiac molecular pathways influenced by doxorubicin treatment in mice. Scientific reports 2019;9:1: (Amsterdam UMC). 210. Burggraaff, CN, de Jong, A, Hoekstra, OS, Hoetjes, NJ, Nievelstein, RAJ, Jansma, EP, Heymans, MW, de Vet, HCW & Zijlstra, JM . Predictive value of interim positron emission tomography in diffuse large B-cell lymphoma. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:1:65-79 (Amsterdam UMC). 211. Bus, S, Verbaan, D, Kerklaan, BJ, Sprengers, MES, Vandertop, WP, Stam, J, Bouma, GJ & van den Munckhof, P . Do older patients with acute or subacute subdural hematoma benefit from surgery?. British Journal of Neurosurgery 2019;33:1:51-57 (Amsterdam UMC). 212. Busson R, van der Kaaij M, Mounier N, Aleman BMP, Thieblemont C, Stamatoullas A, Ribrag V, Tilly H, Haioun C, Casasnovas RO, Kluin-Nelemans HC, Henry-Amar M. Fatigue level changes with time in long-term Hodgkin and non-Hodgkin lymphoma survivors: a joint EORTC-LYSA cross-sectional study. Health Qual Life Outcomes 2019; 17:115 (NKI). 213. Busweiler LAD, Jeremiasen M, Wijnhoven BPL, Lindblad M, Lundell L, van de Velde CJH, Tollenaar RAEM, Wouters MWJM, van Sandick JW, Johansson J, Dikken JL. International benchmarking in oesophageal and gastric cancer surgery. BJS Open 2019; 3:62-73 (NKI). 214. Caballero C, Burock S, Alvarez LC, Nilsson H, Ruers T, Senellart P, Rivoire M, Stattner S, Primavesi F, Troisi R, Gruenberger T, Heil J, Schnitzbauer AA, Rahbari NN, Swijnenburg RJ, Malik H, Protic M, Kataoka K, Mauer M, Ducreux M, Poston G, Evrard S. Building a collaboration to improve surgical research through EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program. Eur J Surg Oncol 2019; 45:1870-5 (Amsterdam UMC & NKI). 215. Caiado F, Maia-Silva D, Jardim C, Schmolka N, Carvalho T, Reforco C, Faria R, Kolundzija B, Simoes AE, Baubec T, Vakoc CR, da Silva MG, Manz MG, Schumacher TN, Norell H, Silva-Santos B. Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection. Nat Commun 2019; 10:4986 (NKI). 216. Campa, D, Matarazzi, M, Greenhalf, W, Bijlsma, M, Saum, K-U, Pasquali, C, van Laarhoven, H, Szentesi, A, Federici, F, Vodicka, P, Funel, N, Pezzilli, R, Bueno-de-Mesquita, HB, Vodickova, L, Basso, D, Obazee, O, Hackert, T, Soucek, P, Cuk, K, Kaiser, JR, Sperti, C, Lovecek, M, Capurso, G, Mohelnikova-Duchonova, B, Khaw, K-T, König, A-K, Kupcinskas, J, Kaaks, R, Bambi, F, Archibugi, L, Mambrini, A, Cavestro, GM, Landi, S, Hegyi, PT, Izbicki, JR, Gioffreda, D, Zambon, CF, Tavano, F, Talar- Wojnarowska, R, Jamroziak, K, Key, TJ, Fave, GD, Strobel, O, Jonaitis, L, Andriulli, A, Lawlor, RT, Pirozzi, F, Katzke, V, Valsuani, C, Vashist, YK, Brenner, H & Canzian, F . Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study. International journal of cancer. Journal international du cancer 2019;144:6:1275-1283 (Amsterdam UMC). 217. Canfell, K, Kim, JJ, Kulasingam, S, Berkhof, J, Barnabas, R, Bogaards, JA, Campos, N, Jennett, C, Sharma, M, Simms, KT, Smith, MA, Velentzis, LS, Brisson, M & Jit, M . HPV-FRAME: A consensus statement and quality framework for modelled evaluations of HPV-related cancer control. PAPILLOMAVIRUS RESEARCH 2019;8::100184. (Amsterdam UMC). 218. Capitanio U, Bensalah K, Bex A, Boorjian SA, Bray F, Coleman J, Gore JL, Sun M, Wood C, Russo P. Epidemiology of Renal Cell Carcinoma. Eur Urol 2019; 75:74-84 (NKI). 219. Capula, M, Mantini, G, Funel, N & Giovannetti, E . New avenues in pancreatic cancer: exploiting microRNAs as predictive biomarkers and new approaches to target aberrant metabolism. Expert Review of Clinical Pharmacology 2019;12:12:1081-1090 (Amsterdam UMC). 220. Carbone M, Adusumilli PS, Alexander HR, Jr. , Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy(NKI). 221. Castillo, J, Knol, JC, Korver, CM, Piersma, SR, Pham, TV, de Goeij-de Haas, RR, van Pelt, AMM, Jimenez, CR & Jansen, BJH . Human testis phosphoproteome reveals kinases as potential targets in spermatogenesis and testicular cancer. Molecular and Cellular Proteomics 2019;18::S132-S144. (Amsterdam UMC). 222. Cats A. No clear role for angiogenesis inhibitors in first-line therapy for stomach cancer. Lancet Oncol 2019; 20:323-4 (NKI). 223. Caumanns JJ, van Wijngaarden A, Kol A, Meersma GJ, Jalving M, Bernards R, van der Zee AGJ, Wisman GBA, de Jong S. Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma. Cancer Lett 2019; 461:102-11 (NKI). 224. Cavaletti G, Cornblath DR, Merkies ISJ, Postma TJ, Rossi E, Alberti P, Bruna J, Argyriou AA, Briani C, Velasco R, Kalofonos HP, Psimaras D, Ricard D, Pace A, Faber CG, Lalisang RI, Brandsma D, Koeppen S, Kerrigan S, Schenone A, Grisold W, Mazzeo A, Padua L, Dorsey SG, Penas-Prado M, Valsecchi MG . Patients' and physicians' interpretation of chemotherapy-induced peripheral neurotoxicity. J Peripher Nerv Syst 2019; 24(1):111-119:111-9 (Amsterdam UMC & NKI). 225. Chadi SA, Beets GL, Perez RO, Renehan AG. Watch-and-wait strategy in rectal cancer - Authors' reply. Lancet Gastroenterol Hepatol 2019; 4:97 [Letter] (NKI). 226. Chan, J, Friborg, J, Chernov, M, Cherkashin, M, Grau, C, Brundage, M & Slotman, B . Access to radiotherapy among circumpolar Inuit populations. Lancet Oncology 2019;20:10:e590-e600 (Amsterdam UMC). 227. Chan, J, Polo, A, Zubizarreta, E, Bourque, J-M, Hanna, TP, Gaudet, M, Dennis, K, Brundage, M, Slotman, B & Abdel-Wahab, M . Access to radiotherapy and its association with cancer outcomes in a high-income country: Addressing the inequity in Canada. Radiotherapy and Oncology 2019;141::48- 55. (Amsterdam UMC). 228. Chau C, van Doorn R, van Poppelen NM, van der Stoep N, Mensenkamp AR, Sijmons RH, van Paassen BW, van den Ouweland AMW, Naus NC, van der Hout AH, Potjer TP, Bleeker FE, Wevers MR, van Hest LP, Jongmans MCJ, Marinkovic M, Bleeker JC, Jager MJ, Luyten GPM, Nielsen M. Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines. Cancers (Basel) 2019; 11:(21 pp) (NKI). 229. Chellapandian, D, Hines, MR, Zhang, R, Jeng, M, van den Bos, C, Santa-María López, V, Lehmberg, K, Sieni, E, Wang, Y, Nakano, T, Williams, JA, Fustino, NJ, Astigarraga, I, Dunkel, IJ, Abla, O, van Halteren, AGS, Pei, D, Cheng, C, Weitzman, S, Sung, L & Nichols, KE . A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis. Cancer 2019;125:6:963-971 (Amsterdam UMC). 230. Chen S, Huang V, Xu X, Livingstone J, Soares F, Jeon J, Zeng Y, Hua JT, Petricca J, Guo H, Wang M, Yousif F, Zhang Y, Donmez N, Ahmed M, Volik S, Lapuk A, Chua MLK, Heisler LE, Foucal A, Fox NS, Fraser M, Bhandari V, Shiah YJ, Guan J, Li J, Orain M, Picard V, Hovington H, Bergeron A, Lacombe L, Fradet Y, Tetu B, Liu S, Feng F, Wu X, Shao YW, Komor MA, Sahinalp C, Collins C, Hoogstrate Y, de Jong M, Fijneman RJA, Fei T, Jenster G, van der Kwast T, Bristow RG, Boutros PC, He HH. Widespread and Functional RNA Circularization in Localized Prostate Cancer. Cell 2019; 176:831-43 (NKI). 231. Christiansen, IS, Bodtger, U, Naur, TMH, Ahmad, K, Singh Sidhu, J, Nessar, R, Salih, GN, Høegholm, A, Annema, JT & Clementsen, PF . EUS-B-FNA for Diagnosing Liver and Celiac Metastases in Lung Cancer Patients. Respiration; international review of thoracic diseases 2019;98:5:428-433 (Amsterdam UMC). 232. Christodoulou M, Blackhall F, Mistry H, Leylek A, Knegjens J, Remouchamps V, Martel-Lafay I, Farre N, Zwitter M, Lerouge D, Pourel N, Janicot H, Scherpereel A, Tissing-Tan C, Peignaux K, Geets X, Konopa K, Faivre-Finn C. Compliance and outcome of elderly patients treated in the Concurrent ONce daily VErsus twice-daily RadioTherapy (CONVERT) trial. J Thorac Oncol 2019; 14:63-71 (NKI). 233. Chung HC, Ros W, Delord JP, Perets R, Italiano A, Shapira-Frommer R, Manzuk L, Piha-Paul SA, Xu L, Zeigenfuss S, Pruitt SK, Leary A. Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase II KEYNOTE-158 Study. J Clin Oncol 2019; 37:1470- 8 (NKI). 234. Cioni B, Jordanova ES, Hooijberg E, van der Linden R, de Menezes RX, Tan K, Willems S, Elbers JBW, Broeks A, Bergman AM, Zuur CL, de Boer JP. HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer. Head Neck 2019; 41:463-78 (Amsterdam UMC & NKI). 235. Claassen YHM, Hartgrink HH, de Steur WO, Dikken JL, van Sandick JW, van Grieken NCT, Cats A, Trip AK, Jansen EPM, Kranenbarg WMM, Braak JPBM, Putter H, van Berge Henegouwen MI, Verheij M, van de Velde CJH. Impact of upfront randomization for postoperative treatment on quality of surgery in the CRITICS gastric cancer trial. Gastric Cancer 2019; 22:369-76 (Amsterdam UMC and NKI). 236. Claassen YHM, van Amelsfoort RM, Hartgrink HH, Dikken JL, de Steur WO, van Sandick JW, van Grieken NCT, Cats A, Boot H, Trip AK, Jansen EPM, Kranenbarg EM, Braak JPBM, Putter H, Henegouwen MIVB, Verheij M, van de Velde CJH. Effect of Hospital Volume With Respect to Performing Gastric Cancer Resection on Recurrence and Survival: Results from the CRITICS Trial. Ann Surg 2019; 270:1096-102 (Amsterdam UMC & NKI). 237. Claassen, YHM, van Amelsfoort, RM, Hartgrink, HH, Dikken, JL, de Steur, WO, van Sandick, JW, van Grieken, NCT, Cats, A, Boot, H, Trip, AK, Jansen, EPM, Kranenbarg, EM-K, Braak, JPBM, Putter, H, Henegouwen, MIVB, Verheij, M & van de Velde, CJH . Effect of Hospital Volume With Respect to Performing Gastric Cancer Resection on Recurrence and Survival: Results From the CRITICS Trial. Annals of surgery 2019;270:6:1096-1102 (Amsterdam UMC). 238. Claeys, S, Denecker, G, Durinck, K, Decaesteker, B, Mus, LM, Loontiens, S, Vanhauwaert, S, Althoff, K, Wigerup, C, Bexell, D, Dolman, E, Henrich, K-O, Wehrmann, L, Westerhout, EM, Demoulin, J-B, Kumps, C, van Maerken, T, Laureys, G, van Neste, C, de Wilde, B, de Wever, O, Westermann, F, Versteeg, R, Molenaar, JJ, Påhlman, S, Schulte, JH, de Preter, K & Speleman, F . ALK positively regulates MYCN activity through repression of HBP1 expression. Oncogene 2019;38:15:2690-2705 (Amsterdam UMC). 239. Clayton, A, Boilard, E, Buzas, EI, Cheng, L, Falcón-Perez, JM, Gardiner, C, Gustafson, D, Gualerzi, A, Hendrix, A, Hoffman, A, Jones, J, Lässer, C, Lawson, C, Lenassi, M, Nazarenko, I, O’Driscoll, L, Pink, R, Siljander, PRM, Soekmadji, C, Wauben, M, Welsh, JA, Witwer, K, Zheng, L & Nieuwland, R . Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles. Journal of extracellular vesicles 2019;8:1: (Amsterdam UMC). 240. Clemens, E, Meijer, AJM, Broer, L, Langer, T, van der Kooi, A-LLF, Uitterlinden, AG, de Vries, A, Kuehni, CE, Garrè, ML, Kepak, T, Kruseova, J, Winther, JF, Kremer, LC, van Dulmen-den Broeder, E, Tissing, WJE, Rechnitzer, C, Kenborg, L, Hasle, H, Grabow, D, Parfitt, R, Binder, H, Carleton, BC, Byrne, J, Kaatsch, P, Zehnhoff-Dinnesen, A, Zolk, O & van den Heuvel-Eibrink, MM . Genetic determinants of ototoxicity during and after childhood cancer treatment: Protocol for the pancarelife study. Journal of medical Internet research 2019;21:3: (Amsterdam UMC). 241. Clement DS, Tesselaar ME, van Leerdam ME, Srirajaskanthan R, Ramage JK. Nutritional and vitamin status in patients with neuroendocrine neoplasms. World J Gastroenterol 2019; 25:1171-84 (NKI). 242. Cloos, J, Ossenkoppele, GJ & Dillon, R . Minimal residual disease and stem cell transplantation outcomes. Hematology. American Society of Hematology. Education Program 2019;2019:1:617-625 (Amsterdam UMC). 243. Codacci-Pisanelli, G, Honeywell, RJ, Asselin, N, Bellettini, G, Peters, GJ, Giovannetti, E & Peccatori, FA . Breastfeeding during R-CHOP chemotherapy: please abstain!. European Journal of Cancer 2019;119::107-111. (Amsterdam UMC). 244. Codari, M, Melazzini, L, Morozov, SP, van Kuijk, CC, Sconfienza, LM & Sardanelli, F . Impact of artificial intelligence on radiology: a EuroAIM survey among members of the European Society of Radiology. Insights into Imaging 2019;10:: (Amsterdam UMC). 245. Cohen EEW, Soulieres D, Le Tourneau C, Dinis J, Licitra L, Ahn MJ, Soria A, Machiels JP, Mach N, Mehra R, Burtness B, Zhang P, Cheng J, Swaby RF, Harrington KJ, KEYNOTE-040 investigators. , (Collaborators 98), de Boer JP. Pembrolizumab versus methotrexate, docetaxel, or cetuximab for recurrent or metastatic head-and-neck squamous cell carcinoma (KEYNOTE-040): a randomised, open-label, phase 3 study(NKI). 246. Collarino, A, Garganese, G, Fragomeni, SM, Pereira Arias-Bouda, LM, Ieria, FP, Boellaard, R, Rufini, V, de Geus-Oei, L-F, Scambia, G, Valdés Olmos, RA, Giordano, A, Grootjans, W & van Velden, FHP . Radiomics in vulvar cancer. Journal of Nuclear Medicine 2019;60:2:199-206 (Amsterdam UMC). 247. Collette, E, den Bakker, M, Klaver, S, Vis, A & Kliffen, M . Partial versus complete prostatectomy specimen sampling: Prospective non-inferiority study for pT3a tumours and surgical margin involvement. BMJ Open 2019;9:4: (Amsterdam UMC). 248. Combes E, Andrade AF, Tosi D, Michaud HA, Coquel F, Garambois V, Desigaud D, Jarlier M, Coquelle A, Pasero P, Bonnefoy N, Moreaux J, Martineau P, Del Rio M, Beijersbergen RL, Vezzio-Vie N, Gongora C. Inhibition of Ataxia-Telangiectasia Mutated and RAD3-related (ATR) overcomes oxaliplatin resistance and promotes anti-tumor immunity in colorectal cancer. Cancer Res 2019; 79:2933-46 (NKI). 249. Comoglio F, Simonatto M, Polletti S, Liu X, Smale ST, Barozzi I, Natoli G. Dissection of acute stimulus- inducible nucleosome remodeling in mammalian cells. Genes Dev 2019; 33:1159-74 (NKI). 250. Comperat EM, Burger M, Gontero P, Mostafid AH, Palou J, Roupret M, van Rhijn BWG, Shariat SF, Sylvester RJ, Zigeuner R, Babjuk M. Grading of Urothelial Carcinoma and The New "World Health Organisation Classification of Tumours of the Urinary System and Male Genital Organs 2016". Eur Urol Focus 2019; 5:457-66 (NKI). 251. Constine, LS, Ronckers, CM, Hua, CH, Olch, A, Kremer, LCM, Jackson, A & Bentzen, SM . Pediatric Normal Tissue Effects in the Clinic (PENTEC): An International Collaboration to Analyse Normal Tissue Radiation Dose–Volume Response Relationships for Paediatric Cancer Patients. Clinical oncology (Royal College of Radiologists (Great Britain)) 2019;31:3:199-207 (Amsterdam UMC). 252. Cooiman, MI, Kleinendorst, L, van der Zwaag, B, Janssen, IMC, Berends, FJ & van Haelst, MM . Genetic analysis in the bariatric clinic; impact of a PTEN gene mutation. Molecular genetics and genomic medicine 2019;7:6: (Amsterdam UMC). 253. Cook MG, Massi D, Szumera-Cieckiewicz A, Van den Oord J, Blokx W, van Kempen LC, Balamurugan T, Bosisio F, Koljenovic S, Portelli F, van Akkooi ACJ. An updated European Organisation for Research and Treatment of Cancer (EORTC) protocol for pathological evaluation of sentinel lymph nodes for melanoma. Eur J Cancer 2019; 114:1-7 (NKI). 254. Coomans MB, Dirven L, Aaronson NK, Baumert BG, van den Bent M, Bottomley A, Brandes AA, Chinot O, Coens C, Gorlia T, Herrlinger U, Keime-Guibert F, Malmstrom A, Martinelli F, Stupp R, Talacchi A, Weller M, Wick W, Reijneveld JC, Taphoorn MJB. Symptom clusters in newly diagnosed glioma patients: which symptom clusters are independently associated with functioning and global health status? Neuro Oncol 2019; 21:1447-57 . (Amsterdam UMC & NKI). 255. Coomans, MB, Dirven, L, Aaronson, NK, Baumert, BG, Van Den Bent, M, Bottomley, A, Brandes, AA, Chinot, O, Coens, C, Gorlia, T, Herrlinger, U, Keime-Guibert, F, Malmström, A, Martinelli, F, Stupp, R, Talacchi, A, Weller, M, Wick, W, Reijneveld, JC & Taphoorn, MJB . Symptom clusters in newly diagnosed glioma patients. Neuro-Oncology 2019;21:11:1447-1457 (Amsterdam UMC). 256. Coppe JP, Mori M, Pan B, Yau C, Wolf DM, Ruiz-Saenz A, Brunen D, Prahallad A, Cornelissen-Steijger P, Kemper K, Posch C, Wang C, Dreyer CA, Krijgsman O, Lee PRE, Chen Z, Peeper DS, Moasser MM, Bernards R, van 't Veer LJ. Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities. Nat Cell Biol 2019; 21:778-90 (NKI). 257. COPRAC study group, van Rijssen, LB, Gerritsen, A, Henselmans, I, Sprangers, MA, Jacobs, M, Bassi, C, Busch, OR, Fernández-del Castillo, C, Fong, ZV, He, J, Jang, J-Y, Javed, AA, Kim, S-W, Maggino, L, Mitra, A, Ostwal, V, Pellegrini, S, Shrikhande, SV, Wilmink, JW, Wolfgang, CL, van Laarhoven, HW & Besselink, MG . Core Set of Patient-reported Outcomes in Pancreatic Cancer (COPRAC): An International Delphi Study Among Patients and Health Care Providers. Annals of surgery 2019;270:1:158-164 (Amsterdam UMC). 258. Cornelissen LM, De Bruijn R, Henneman L, Kim Y, Zwart W, Jonkers J. GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice. J Mammary Gland Biol Neoplasia 2019; 24:271-84 (NKI). 259. Cornelissen LM, Henneman L, Drenth AP, Schut E, De Bruijn R, Klarenbeek S, Zwart W, Jonkers J. Exogenous ERalpha Expression in the Mammary Epithelium Decreases Over Time and Does Not Contribute to p53-Deficient Mammary Tumor Formation in Mice. J Mammary Gland Biol Neoplasia 2019; 24:305-21 (NKI). 260. Cornelissen, LAM, Blanas, A, van der Horst, JC, Kruijssen, L, Zaal, A, O. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. International Journal of Cancer 2019 (Amsterdam UMC). 261. Corradini, S, Alongi, F, Andratschke, N, Belka, C, Boldrini, L, Cellini, F, Debus, J, Guckenberger, M, Hörner-Rieber, J, Lagerwaard, FJ, Mazzola, R, Palacios, MA, Philippens, MEP, Raaijmakers, CPJ, Terhaard, CHJ, Valentini, V & Niyazi, M . MR-guidance in clinical reality: Current treatment challenges and future perspectives. Radiation Oncology 2019;14:1: (Amsterdam UMC). 262. Cosgrove C, Dellacecca ER, van den Berg JH, Haanen JB, Nishimura MI, Le Poole I, Bergmans HEN. Transgenerational transfer of gene-modified T cells. J Immunother Cancer 2019; 7:186 (NKI). 263. Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, dam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andra I, Annunziato F, Anselmo A, Bacher P, Baldari CT, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman DA, Bogdan C, Borger JG, Borsellino G, Boulais PE, Bradford JA, Brenner D, Brinkman RR, Brooks AES, Busch DH, Buscher M, Bushnell TP, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell SL, Casola S, Cassatella MA, Cavani A, Celada A, Chatenoud L, Chattopadhyay PK, Chow S, Christakou E, Cicin-Sain L, Clerici M, Colombo FS, Cook L, Cooke A, Cooper AM, Corbett AJ, Cosma A, Cosmi L, Coulie PG, Cumano A, Cvetkovic L, Dang VD, ng-Heine C, Davey MS, Davies D, De Biasi S, Del Zotto G, la Cruz GV, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo JP, Diefenbach A, Dieli F, Dolf A, Dorner T, Dress RJ, Dudziak D, Dustin M, Dutertre CA, Ebner F, Eckle SBG, Edinger M, Eede P, Ehrhardt GRA, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk CS, Fehniger TA, Felipo- Benavent M, Ferry H, Feuerer M, Filby A, Filkor K, Fillatreau S, Follo M, Forster I, Foster J, Foulds GA, Frehse B, Frenette PS, Frischbutter S, Fritzsche W, Galbraith DW, Gangaev A, Garbi N, Gaudilliere B, Gazzinelli RT, Geginat J, Gerner W, Gherardin NA, Ghoreschi K, Gibellini L, Ginhoux F, Goda K, Godfrey DI, Goettlinger C, Gonzalez-Navajas JM, Goodyear CS, Gori A, Grogan JL, Grummitt D, Grutzkau A, Haftmann C, Hahn J, Hammad H, Hammerling G, Hansmann L, Hansson G, Harpur CM, Hartmann S, Hauser A, Hauser AE, Haviland DL, Hedley D, Hernandez DC, Herrera G, Herrmann M, Hess C, Hofer T, Hoffmann P, Hogquist K, Holland T, Hollt T, Holmdahl R, Hombrink P, Houston JP, Hoyer BF, Huang B, Huang FP, Huber JE, Huehn J, Hundemer M, Hunter CA, Hwang WYK, Iannone A, Ingelfinger F, Ivison SM, Jack HM, Jani PK, Javega B, Jonjic S, Kaiser T, Kalina T, Kamradt T, Kaufmann SHE, Keller B, Ketelaars SLC, Khalilnezhad A, Khan S, Kisielow J, Klenerman P, Knopf J, Koay HF, Kobow K, Kolls JK, Kong WT, Kopf M, Korn T, Kriegsmann K, Kristyanto H, Kroneis T, Krueger A, Kuhne J, Kukat C, Kunkel D, Kunze-Schumacher H, Kurosaki T, Kurts C, Kvistborg P, Kwok I, Landry J, Lantz O, Lanuti P, LaRosa F, Lehuen A, LeibundGut-Landmann S, Leipold MD, Leung LYT, Levings MK, Lino AC, Liotta F, Litwin V, Liu Y, Ljunggren HG, Lohoff M, Lombardi G, Lopez L, Lopez-Botet M, Lovett-Racke AE, Lubberts E, Luche H, Ludewig B, Lugli E, Lunemann S, Maecker HT, Maggi L, Maguire O, Mair F, Mair KH, Mantovani A, Manz RA, Marshall AJ, Martinez-Romero A, Martrus G, Marventano I, Maslinski W, Matarese G, Mattioli AV, Maueroder C, Mazzoni A, McCluskey J, McGrath M, McGuire HM, McInnes IB, Mei HE, Melchers F, Melzer S, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). Eur J Immunol 2019; 49:1457-973 (Amsterdam UMC & NKI). 264. Cover, KS, Duvivier, KM, de Graaf, P, Wittenberg, R, Smit, R, Kuijer, JPA, Hofman, MBM, Slotman, BJ & Verdaasdonk, RM . Summarizing the 4D image stack of ultrafast dynamic contrast enhancement MRI of breast cancer in 3D using color intensity projections. Journal of magnetic resonance imaging : JMRI 2019;49:5:1391–1399 (Amsterdam UMC). 265. Cox OT, Edmunds SJ, Simon-Keller K, Li B, Moran B, Buckley NE, Bustamante-Garrido M, Healy N, O'Flanagan CH, Gallagher WM, Kennedy RD, Bernards R, Caldas C, Chin SF, Marx A, O'Connor R. PDLIM2 is a marker of adhesion and beta-catenin activity in triple-negative breast cancer. Cancer Res 2019; 79:2619-33 (NKI). 266. Cretella, D, Digiacomo, G, Giovannetti, E & Cavazzoni, A . PTEN alterations as a potential mechanism for tumor cell escape from PD-1/PD-L1 inhibition. Cancers (Basel) 2019;11:9: (Amsterdam UMC). 267. Crezee, H, Kok, HP, Oei, AL, Franken, NAP & Stalpers, LJA . The impact of the time interval between radiation and hyperthermia on clinical outcome in patients with locally advanced cervical cancer. Frontiers in oncology 2019;9:: (Amsterdam UMC). 268. Cristiano S, Leal A, Phallen J, Fiksel J, Adleff V, Bruhm DC, Jensen SO, Medina JE, Hruban C, White JR, Palsgrove DN, Niknafs N, Anagnostou V, Forde P, Naidoo J, Marrone K, Brahmer J, Woodward BD, Husain H, van Rooijen KL, Orntoft MW, Madsen AH, van de Velde CJH, Verheij M, Cats A, Punt CJA, Vink GR, van Grieken NCT, Koopman M, Fijneman RJA, Johansen JS, Nielsen HJ, Meijer GA, Andersen CL, Scharpf RB, Velculescu VE. Genome-wide cell-free DNA fragmentation in patients with cancer. Nature 2019; 570:385-9 (NKI). 269. Crombag LMM, Dooms C, Stigt JA, Tournoy KG, Schuurbiers OCJ, Ninaber MK, Buikhuisen WA, Hashemi SMS, Bonta PI, Korevaar DA, Annema JT. Systematic and combined endosonographic staging of lung cancer (SCORE Study). Eur Respir J 2019; 53:1800800 (NKI). 270. Crombag MBS, de Vries Schultink AHM, Koolen SLW, Wijngaard S, Joerger M, Schellens JHM, Dorlo TPC, van Erp NP, Mathijssen RHJ, Beijnen JH, Huitema ADR. Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study. Pharm Res 2019; 36:33 (NKI). 271. Crombag MBS, de Vries Schultink AHM, van Doremalen JGC, Otten HM, Bergman AM, Schellens JHM, Beijnen JH, Huitema ADR. Age-Associated Hematological Toxicity in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Docetaxel in Clinical Practice. Drugs Aging 2019; 36:379-85 (NKI). 272. Crombag MBS, Dorlo TPC, van der Pan E, van Straten A, Bergman AM, van Erp NP, Beijnen JH, Huitema ADR. Exposure to Docetaxel in the Elderly Patient Population: a Population Pharmacokinetic Study. Pharm Res 2019; 36:181 (NKI). 273. Crombag MBS, Koolen SLW, Wijngaard S, Joerger M, Dorlo TPC, van Erp NP, Mathijssen RHJ, Beijnen JH, Huitema ADR. Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel? Pharm Res 2019; 36:163 . (NKI). 274. Crombag MBS, van Nuland M, Bergman AM, Rosing H, Schellens JHM, Huitema ADR, Beijnen JH. Impact of age on exposure to oral antiandrogen therapies in clinical practice. Prostate Cancer Prostatic Dis 2019; 22:168-75 (NKI). 275. Crombag, LMM, Dooms, C, Stigt, JA, Tournoy, KG, Schuurbiers, OCJ, Ninaber, MK, Buikhuisen, WA, Hashemi, SMS, Bonta, PI, Korevaar, DA & Annema, JT . Systematic and combined endosonographic staging of lung cancer (SCORE study). European respiratory journal 2019;53:2: (Amsterdam UMC). 276. Cuypers, M, Al-Itejawi, HHM, van Uden-Kraan, CF, Stalmeier, PFM, Lamers, RED, van Oort, IM, Somford, DM, van Moorselaar, RJA, Verdonck-de Leeuw, IM, van de Poll-Franse, LV, van Tol- Geerdink, JJ & de Vries, M . Introducing Decision Aids into Routine Prostate Cancer Care in The Netherlands: Implementation and Patient Evaluations from the Multi-regional JIPPA Initiative. Journal of Cancer Education 2019 (Amsterdam UMC). 277. Cysouw MCF, Golla SVS, Frings V, Smit EF, Hoekstra OS, Kramer GM, Boellaard R. Partial-volume correction in dynamic PET-CT: effect on tumor kinetic parameter estimation and validation of simplified metrics. EJNMMI Res 2019; 9:12 (Amsterdam UMC & NKI). 278. Cysouw, MCF, Kramer, GM, Heijtel, D, Schuit, RC, Morris, MJ, van den Eertwegh, AJM, Voortman, J, Hoekstra, OS, Oprea-Lager, DE & Boellaard, R . Sensitivity of 18F-fluorodihydrotestosterone PET-CT to count statistics and reconstruction protocol in metastatic castration-resistant prostate cancer. EJNMMI Research 2019;9:1: (Amsterdam UMC). 279. D’Hondt, M, Ovaere, S, Knol, J, Vandeputte, M, Parmentier, I, de Meyere, C, Vansteenkiste, F, Besselink, M, Pottel, H & Verslype, C . Laparoscopic right posterior sectionectomy: single-center experience and technical aspects. Langenbeck s archives of surgery / Deutsche Gesellschaft fur Chirurgie 2019;404:1:21-29 (Amsterdam UMC). 280. Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandez-Pello S, Monagas S, Williams SP, Powles T, van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Increased use of cross-sectional imaging for follow-up does not improve post-recurrence survival of surgically treated initially localized R.C.C.: results from a European multicenter database (R.E.C.U.R.). Scand J Urol 2019; 53:14-20 (NKI). 281. Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandez-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Intensive Imaging-based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-recurrence Survival: Results from a European Multicentre Database (RECUR). Eur Urol 2019; 75:261-4 (NKI). 282. Dabestani S, Beisland C, Stewart GD, Bensalah K, Gudmundsson E, Lam TB, Gietzmann W, Zakikhani P, Marconi L, Fernandez-Pello S, Monagas S, Williams SP, Torbrand C, Powles T, van Werkhoven E, Meijer R, Volpe A, Staehler M, Ljungberg B, Bex A. Long-term Outcomes of Follow-up for Initially Localised Clear Cell Renal Cell Carcinoma: RECUR Database Analysis. Eur Urol Focus 2019; 5:857-66 (NKI). 283. Dafni U, Michielin O, Lluesma SM, Tsourti Z, Polydoropoulou V, Karlis D, Besser MJ, Haanen J, Svane IM, Ohashi PS, Kammula US, Orcurto A, Zimmermann S, Trueb L, Klebanoff CA, Lotze MT, Kandalaft LE, Coukos G. Efficacy of Adoptive Therapy with Tumor-infiltrating Lymphocytes and Recombinant Interleukin-2 in Advanced Cutaneous Melanoma: A Systematic Review and Meta-analysis. Ann Oncol 2019; 30:1902-13 (NKI). 284. Das, SK, McGurk, R, Miften, M, Sasa, M, Bowsher, J, Bayouth, J, Erdi, Y, Mawlawi, O, Boellaard, R, Bowen, SR, Xing, L, Bradley, J, Schoder, H, Yin, F-F, Sullivan, DC & Kinahan, P . Task Group 174 Report: Utilization of [ 18 F]Fluorodeoxyglucose Positron Emission Tomography ([ 18 F]FDG-PET) in Radiation Therapy. Medical Physics 2019;46:10:e706-e725 (Amsterdam UMC). 285. DCOG‐LATER Study Group, Feijen, EAML, Font-Gonzalez, A, van der Pal, HJH, Kok, WEM, Geskus, RB, Ronckers, CCM, Bresters, D, van Dalen, EC, van Dulmen-den Broeder, E, van den Berg, MH, van der Heiden-van der Loo, M, van den Heuvel-Eibrink, MM, van Leeuwen, FE, Loonen, JJ, Neggers, SJCMM, Versluys, ABB, Tissing, WJE & Kremer, LCM . Risk and Temporal Changes of Heart Failure Among 5- Year Childhood Cancer Survivors: a DCOG-LATER Study. Journal of the American Heart Association 2019;8:1: (Amsterdam UMC). 286. de Bitter, TJJ, van der Linden, RLA, van Vliet, S, Weren, F, Sie, D, Ylstra, B, van der Linden, HC, Knijn, N, Ligtenberg, MJL, van der Post, RS, Simmer, F & Nagtegaal, ID . Colorectal metastasis to the gallbladder mimicking a primary gallbladder malignancy. Histopathology 2019;75:3:394-404 (Amsterdam UMC). 287. de Blok CJM, Wiepjes CM, Nota NM, van Engelen K, Adank MA, Dreijerink KMA, Barbe E, Konings IRHM, den Heijer M. Breast cancer risk in transgender people receiving hormone treatment: nationwide cohort study in the Netherlands. BMJ 2019; 365:l1652 (NKI). 288. de Blok, CJM, Dreijerink, KMA & den Heijer, M . Cancer Risk in Transgender People. Endocrinology and Metabolism Clinics of North America 2019;48:2:441-452 (Amsterdam UMC). 289. de Boer L, Kho E, Nijkamp J, Van de Vijver K, Sterenborg HJC, Ter Beek L, Ruers TJ. Method for coregistration of optical measurements of breast tissue with histopathology: the importance of accounting for tissue deformations. J Biomed Opt 2019; 24:1-12 (NKI). 290. de Boer, DV, Brink, A, Buijze, M, Stigter-van Walsum, M, Hunter, KD, Ylstra, B, Bloemena, E, Leemans, CR & Brakenhoff, RH . Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal Lining. Molecular Cancer Research 2019;17:1:120-130 (Amsterdam UMC). 291. de Boer, L, Kho, E, Nijkamp, J, van de Vijver, K, Sterenborg, HJC, ter Beek, L & Ruers, TJ . Method for coregistration of optical measurements of breast tissue with histopathology: the importance of accounting for tissue deformations. Journal of biomedical optics 2019;24:7:44166 (Amsterdam UMC). 292. de Boer, LL, Kho, E, Józwiak, K, van de Vijver, KK, Vrancken Peeters, M-JTFD, van Duijnhoven, F, Hendriks, BHW, Sterenborg, HJCM & Ruers, TJM . Influence of neoadjuvant chemotherapy on diffuse reflectance spectra of tissue in breast surgery specimens. Journal of biomedical optics 2019;24:11: (Amsterdam UMC). 293. de Boer, P, Mandija, S, Werensteijn-Honingh, AM, van den Berg, CAT, de Leeuw, AAC & Jürgenliemk- Schulz, IM . Cervical cancer apparent diffusion coefficient values during external beam radiotherapy. Physics and Imaging in Radiation Oncology 2019;9::77-82 (Amsterdam UMC). 294. de Boer, P, Spijkerboer, AM, Bleeker, MCG, van Lonkhuijzen, LRCW, Monraats, MLA, Nederveen, AJ, van de Vijver, MJ, Kenter, GG, Bel, A, Rasch, CRN, Stoker, J & Stalpers, LJA . Prospective validation of craniocaudal tumour size on MR imaging compared to histoPAthology in patients with uterine cervical cancer: The MPAC study. Clinical and Translational Radiation Oncology 2019;18::42248 (Amsterdam UMC). 295. De Bruijn RE, Mulders P, Jewett MA, Wagstaff J, van Thienen JV, Blank CU, van Velthoven R, Wood L, van Melick HE, Aarts MJ, Lattouf JB, Powles T, de Jong J, Rottey S, Tombal B, Marreaud S, Collette S, Collette L, Haanen JB, Bex A. Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME). Eur Urol 2019; 76:437-40 (NKI). 296. de Goeje PL, Poncin M, Bezemer K, Kaijen-Lambers MEH, Groen HJ, Smit EF, Dingemans AC, Kunert A, Hendriks RW, Aerts JG. Induction of peripheral effector CD8 T cell proliferation by combination of paclitaxel, carboplatin and bevacizumab in non-small cell lung cancer patients. Clin Cancer Res 2019; 25:2219-27 (Amsterdam UMC & NKI). 297. de Groen, RAL, Schrader, AMR, Kersten, MJ, Pals, ST & Vermaat, JSP . MYD88 in the driver's seat of B- cell lymphomagenesis: from molecular mechanisms to clinical implications. Haematologica 2019;104:12:2337-2348 (Amsterdam UMC). 298. de Groof, AJ, Swager, A-F, Pouw, RE, Weusten, BLAM, Schoon, EJ, Bisschops, R, Pech, O, Meining, A, Neuhaus, H, Curvers, WL & Bergman, JJGHM . Blue-light imaging has an additional value to white- light endoscopy in visualization of early Barrett's neoplasia: an international multicenter cohort study. Gastrointestinal endoscopy 2019;89:4:749-758 (Amsterdam UMC). 299. De Groot R, Van Loenen MM, Guislain A, Nicolet BP, Freen-Van Heeren JJ, Verhagen OJHM, van den Heuvel MM, de Jong J, Burger P, Van Der Schoot CE, Spaapen RM, Amsen D, Haanen JBAG, Monkhorst K, Hartemink KJ, Wolkers MC. Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile. Oncoimmunology 2019; 8:e1648170 (14 pp) (NKI). 300. de Groot, R, van Loenen, MM, Guislain, A, Nicolet, BP, Freen-van Heeren, JJ, Verhagen, OJHM, van den Heuvel, MM, de Jong, J, Burger, P, van der Schoot, CE, Spaapen, RM, Amsen, D, Haanen, JBAG, Monkhorst, K, Hartemink, KJ & Wolkers, MC . Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile. Oncoimmunology 2019;8:11: (Amsterdam UMC). 301. de Groot, S, Pijl, H, Charehbili, A, van de Ven, S, Smit, VTHBM, Meershoek-Klein Kranenbarg, E, Heijns, JB, van Warmerdam, LJC, Kessels, LW, Dercksen, MW, Pepels, MJAE, van Laarhoven, HWM, Vriens, BEPJ, Putter, H, Fiocco, M, Liefers, G-J, van der Hoeven, JJM, Nortier, JWR & Kroep, JR . Addition of zoledronic acid to neoadjuvant chemotherapy is not beneficial in patients with HER2- negative stage II/III breast cancer: 5-year survival analysis of the NEOZOTAC trial (BOOG 2010-01). Breast cancer research 2019;21:1: (Amsterdam UMC). 302. de Haan R, van Werkhoven E, van den Heuvel MM, Peulen HMU, Sonke GS, Elkhuizen P, van den Brekel MWM, Tesselaar MET, Vens C, Schellens JHM, van Triest B, Verheij M. Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib. BMC Cancer 2019; 19:901 (Amsterdam UMC & NKI). 303. de Hosson, LD, van der Loo-van der Schaaf, AM, Boellaard, R, van Snick, JH, de Vries, EGE, Brouwers, AH & Walenkamp, AME . Interlesional Heterogeneity of Metastatic Neuroendocrine Tumors Based on 18F-DOPA PET/CT. Clinical Nuclear Medicine 2019;44:8:612-619 (Amsterdam UMC). 304. De Jaeghere EA, Gremonprez FB, Tummers PG, Willaert WC, Ceelen WP, Amant FC, Denys HG. Treatment of Ovarian Cancer With Intraperitoneal Platinum: Heating Up the Debate. J Clin Oncol 2019; 37:3169-70 (NKI). 305. de Jong JJ, Liu Y, Robertson AG, Seiler R, Groeneveld CS, van der Heijden MS, Wright JL, Douglas J, Dall'Era M, Crabb SJ, van Rhijn BWG, van Kessel KEM, Davicioni E, Castro MAA, Lotan Y, Zwarthoff EC, Black PC, Boormans JL, Gibb EA. Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis. Genome Med 2019; 11:60 (NKI). 306. de Jong Y, Ingola M, Briaire-de B, I, Kruisselbrink AB, Venneker S, Palubeckaite I, Heijs BPAM, Cleton- Jansen AM, Haas RLM, Bovee JVMG. Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes. Clin Sarcoma Res 2019; 9:9 (NKI). 307. de Jong, CN, Meijer, E, Bakunina, K, Nur, E, van Marwijk Kooij, M, de Groot, MR, van Gelder, M, Maertens, JA, Kuball, JHE, Deeren, D, van der Holt, B, Cornelissen, JJ & Broers, AEC . Post- Transplantation Cyclophosphamide after Allogeneic Hematopoietic Stem Cell Transplantation: Results of the Prospective Randomized HOVON-96 Trial in Recipients of Matched Related and Unrelated Donors. Blood 2019;134:1:1 (Amsterdam UMC). 308. de Jong, G, Janssen, JJWM, Biemond, BJ, Zeerleder, SS, Ossenkoppele, GJ, Visser, O, Nur, E, Meijer, E & Hazenberg, MD . Survival of early posthematopoietic stem cell transplantation relapse of myeloid malignancies. European journal of haematology 2019;103:5:491-499 (Amsterdam UMC). 309. de Jonge MJA, Steeghs N, Lolkema MP, Hotte SJ, Hirte HW, van der Biessen DAJ, Abdul Razak AR, De Vos FYFL, Verheijen RB, Schnell D, Pronk LC, Jansen M, Siu LL. Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies. Target Oncol 2019; 14:43-55 (NKI). 310. de Jonge MM, Ritterhouse LL, de Kroon CD, Vreeswijk MPG, Segal JP, Puranik R, Study H, Hollema H, Rookus MA, van Asperen CJ, van Leeuwen FE, Smit VTHB, Howitt BE, Bosse T. Germline BRCA- associated Endometrial Carcinoma is a Distinct Clinicopathologic Entity. Clin Cancer Res 2019; 25:7517-26 (NKI). 311. de Klerk, CM, Wieten, E, Lansdorp-Vogelaar, I, Bossuyt, PM, Spaander, MCW & Dekker, E . Performance of two faecal immunochemical tests for the detection of advanced neoplasia at different positivity thresholds: a cross-sectional study of the Dutch national colorectal cancer screening programme. lancet. Gastroenterology & hepatology 2019;4:2:111-118 (Amsterdam UMC). 312. de Klerk, CM, Woudstra, AJ, Fransen, MP, Bossuyt, PM & Dekker, E . Invitees do not adequately act on alarm symptoms in colorectal cancer screening with fecal immunochemical tests. European journal of gastroenterology & hepatology 2019;31:1:141-142 (Amsterdam UMC). 313. de Korne CM, Wit EM, de Jong J, Valdes Olmos RA, Buckle T, van Leeuwen FWB, van der Poel HG. Anatomical localization of radiocolloid tracer deposition affects outcome of sentinel node procedures in prostate cancer. Eur J Nucl Med Mol Imaging 2019; 46:2558-68 (NKI). 314. de Kruif, JTCM, Visser, M, van den Berg, MMGA, Derks, MJM, de Boer, MR, van Laarhoven, HWM, de Vries, JHM, de Vries, YC, Kampman, E, Winkels, RW & Westerman, MJ . A longitudinal mixed methods study on changes in body weight, body composition, and lifestyle in breast cancer patients during chemotherapy and in a comparison group of women without cancer: Study protocol. BMC cancer 2019;19:1: (Amsterdam UMC). 315. de Lande, RSV, Maurice-Stam, H, Marchal, JP, Vuurden, DGV, Vandertop, WP, Grootenhuis, MA & Schouten-van Meeteren, AYN . Adaptive behavior impaired in children with low-grade glioma. Pediatric Blood and Cancer 2019;66:1: (Amsterdam UMC). 316. de Lange, NM, Ezendam, NPM, Kwon, JS, Vandenput, I, Mirchandani, D, Amant, F, van der Putten, LJM & Pijnenborg, JMA . Neoadjuvant chemotherapy followed by surgery for advanced-stage endometrial cancer. Current oncology (Toronto, Ont.) 2019;26:2:e226-e232 (Amsterdam UMC). 317. de Ligt KM, Heins M, Verloop J, Ezendam NPM, Smorenburg CH, Korevaar JC, Siesling S. The impact of health symptoms on health-related quality of life in early-stage breast cancer survivors. Breast Cancer Res Treat 2019; 178:703-11 (NKI). 318. de Ligt KM, Heins M, Verloop J, Smorenburg CH, Korevaar JC, Siesling S. Patient-reported health problems and healthcare use after treatment for early-stage breast cancer. Breast 2019; 46:4-11 (NKI). 319. de Man FM, Veerman GDM, Oomen-de Hoop E, Deenen MJ, Meulendijks D, Mandigers CMPW, Soesan M, Schellens JHM, van Meerten E, van Gelder T, Mathijssen RHJ. Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine. Ther Adv Med Oncol 2019; 11:1758835919838964 (14 pp) (NKI). 320. de Man, Y, Atsma, F, Oosterveld-Vlug, MG, Brom, L, Onwuteaka-Philipsen, BD, Westert, GP & Groenewoud, AS . The Intensity of Hospital Care Utilization by Dutch Patients With Lung or Colorectal Cancer in their Final Months of Life. Cancer Control 2019;26:: (Amsterdam UMC). 321. de Moel EC, Rozeman EA, Kapiteijn EHW, Verdegaal EME, Grummels A, Bakker JA, Huizinga TWJ, Haanen JBAG, Toes REM, van der Woude D. Autoantibody development under treatment with immune checkpoint inhibitors. Cancer Immunol Res 2019; 7:6-11 (NKI). 322. de Moerloose, B, Reedijk, A, de Bock, GH, Lammens, T, de Haas, V, Denys, B, Dedeken, L, van den Heuvel-Eibrink, MM, te Loo, M, Uyttebroeck, A, van Damme, A, van der Werff-ten Bosch, J, Zsiros, J, Kaspers, G & de Bont, E . Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01. Pediatric Blood and Cancer 2019;66:5: (Amsterdam UMC). 323. de Ridder M, Gouw ZAR, Navran A, Hamming-Vrieze O, Jasperse B, van den Brekel MWM, Vogel WV, Al-Mamgani A. FDG-PET/CT improves detection of residual disease and reduces the need for examination under anaesthesia in oropharyngeal cancer patients treated with (chemo-)radiation. Eur Arch Otorhinolaryngol 2019; 276:1447-55 (Amsterdam UMC & NKI). 324. de Rijk, A, Amir, Z, Cohen, M, Furlan, T, Godderis, L, Knezevic, B, Miglioretti, M, Munir, F, Popa, AE, Sedlakova, M, Torp, S, Yagil, D, Tamminga, S & de Boer, A . The challenge of return to work in workers with cancer: employer priorities despite variation in social policies related to work and health. Journal of cancer survivorship 2019 (Amsterdam UMC). 325. De Roest, RH, Mes, SW, Poell, JB, Brink, A, Van De Wiel, MA, Bloemena, E, Thai, E, Poli, T, Leemans, CR & Brakenhoff, RH . Molecular characterization of locally relapsed head and neck cancer after concomitant chemoradiotherapy. Clinical Cancer Research 2019;25:23:7256-7265 (Amsterdam UMC). 326. de Rond, L, Libregts, SFWM, Rikkert, LG, Hau, CM, van der Pol, E, Nieuwland, R, van Leeuwen, TG & Coumans, FAW . Refractive index to evaluate staining specificity of extracellular vesicles by flow cytometry. Journal of extracellular vesicles 2019;8:1: (Amsterdam UMC). 327. de Rooij, T, van Hilst, J, Topal, B, Bosscha, K, Brinkman, DJ, Gerhards, MF, de Hingh, IH, Karsten, TM, Lips, DJ, Luyer, MD, Marsman, HA, van Rijssen, LB, Steen, MW, Busch, OR, Festen, S & Besselink, MG . Outcomes of a Multicenter Training Program in Laparoscopic Pancreatoduodenectomy (LAELAPS-2). Annals of surgery 2019;269:2:344-350 (Amsterdam UMC). 328. de Rooij, T, van Hilst, J, van Santvoort, H, Boerma, D, van den Boezem, P, Daams, F, van Dam, R, Dejong, C, van Duyn, E, Dijkgraaf, M, van Eijck, C, Festen, S, Gerhards, M, Groot Koerkamp, B, de Hingh, I, Kazemier, G, Klaase, J, de Kleine, R, van Laarhoven, C, Luyer, M, Patijn, G, Steenvoorde, P, Suker, M, Abu Hilal, M, Busch, O, Besselink, M & Dutch Pancreatic Cancer Group . Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD): A Multicenter Patient-blinded Randomized Controlled Trial. Annals of Surgery 2019;269:1:44076 (Amsterdam UMC). 329. de Veij Mestdagh PD, Janssen T, Lamers E, Carbaat C, Hamming-Vrieze O, Vogel WV, Sonke JJ, Al- Mamgani A. SPECT/CT-guided elective nodal irradiation for head and neck cancer: Estimation of clinical benefits using NTCP models. Radiother Oncol 2019; 130:18-24 (NKI). 330. de Veij Mestdagh PD, Schreuder WH, Vogel WV, Donswijk ML, van Werkhoven E, van der Wal JE, Dirven R, Karakullukcu B, Sonke JJ, van den Brekel MWM, Marijnen CAM, Al-Mamgani A. Mapping of sentinel lymph node drainage using SPECT/CT to tailor elective nodal irradiation in head and neck cancer patients (SUSPECT-2): a single-center prospective trial. BMC Cancer 2019; 19:1110 (NKI). 331. de Veij Mestdagh PD, van Werkhoven E, Navran A, de Boer JP, Schreuder WH, Vogel WV, Al- Mamgani A. Incidence of contralateral regional failure in the electively irradiated contralateral neck of patients with head and neck squamous cell carcinoma. Clin Transl Radiat Oncol 2019; 17:7-13 (NKI). 332. de Vos-Geelen, J, Geurts, SM, van Putten, M, Valkenburg-van Iersel, LB, Grabsch, HI, Haj Mohammad, N, Hoebers, FJ, Hoge, CV, Jeene, PM, de Jong, EJ, van Laarhoven, HW, Rozema, T, Slingerland, M, Tjan-Heijnen, VC, Nieuwenhuijzen, GA & Lemmens, VE . Trends in treatment and overall survival among patients with proximal esophageal cancer. World journal of gastroenterology 2019;25:47:6835-6846 (Amsterdam UMC). 333. de Vries EGE, Cherny NI, Voest EE. When is off-label off-road? Ann Oncol 2019; 30:1536-8 . (NKI). 334. de Vries HM, Brouwer OR, Heijmink S, Horenblas S, Vegt E . Recent developments in penile cancer imaging. Curr Opin Urol 2019; 29:150-5 (NKI). 335. de Vries HM, Ottenhof SR, Horenblas S, van der Heijden MS, Jordanova ES. Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram. Eur Urol Focus 2019; 5:718-21 (NKI). 336. de Vries R, Muller M, van der Noort V, Theelen WSME, Schouten RD, Hummelink K, Muller SH, Wolf- Lansdorf M, Dagelet JWF, Monkhorst K, Maitland-van der Zee AH, Baas P, Sterk PJ, van den Heuvel MM. Prediction of response to anti-PD-1 therapy in patients with non-small-cell lung cancer by electronic nose analysis of exhaled breath. Ann Oncol 2019; 30:1660-6 (Amsterdam UMC & NKI). 337. de Vries Schultink AHM, Crombag MBS, van Werkhoven E, Otten HM, Bergman AM, Schellens JHM, Huitema ADR, Beijnen JH. Neutropenia and docetaxel exposure in metastatic castration-resistant prostate cancer patients: A meta-analysis and evaluation of a clinical cohort. Cancer Med 2019; 8:1406-15 (NKI). 338. de Vries, H-M, Ottenhof, SR, Horenblas, S, van der Heijden, MS & Jordanova, ES . Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram. European Urology Focus 2019;5:5:718-721 (Amsterdam UMC). 339. de Vries, R, Muller, M, van der Noort, V, Theelen, WSME, Schouten, RD, Hummelink, K, Muller, SH, Wolf-Lansdorf, M, Dagelet, JWF, Monkhorst, K, Maitland-van der Zee, AH, Baas, P, Sterk, PJ & van den Heuvel, MM . Prediction of response to anti-PD-1 therapy in patients with non-small-cell lung cancer by electronic nose analysis of exhaled breath. Annals of oncology 2019;30:10:1660-1666 (Amsterdam UMC). 340. de Vries, YC, Boesveldt, S, Kampman, E, de Graaf, C, Winkels, RM & van Laarhoven, HWM . Low reported taste function is associated with low preference for high protein products in advanced oesophagogastric cancer patients undergoing palliative chemotherapy. Clinical nutrition (Edinburgh, Scotland) 2019;38:1:472-475 (Amsterdam UMC). 341. de Weerdt, I & Kater, AP . Combining novel agents in chronic lymphocytic leukemia: Greater than the sum of its parts?. HemaSphere 2019;3:S2:44-46 (Amsterdam UMC). 342. de Weerdt, I, Hofland, T, de Boer, R, Dobber, JA, Dubois, J, van Nieuwenhuize, D, Mobasher, M, de Boer, F, Hoogendoorn, M, Velders, GA, van der Klift, M, Remmerswaal, EBM, Bemelman, FJ, Niemann, CU, Kersting, S, Levin, M-D, Eldering, E, Tonino, SH & Kater, AP . Distinct immune composition in lymph node and peripheral blood of CLL patients is reshaped during venetoclax treatment. Blood advances 2019;3:17:2642-2652 (Amsterdam UMC). 343. de Weger V, de Jonge M, Langenberg MHG, Schellens JHM, Lolkema M, Varga A, Demers B, Thomas K, Hsu K, Tuffal G, Goodstal S, Mace S, Deutsch E. A phase I study of the HDM2 antagonist SAR405838 combined with the MEK inhibitor pimasertib in patients with advanced solid tumours. Br J Cancer 2019; 120:286-93 (NKI). 344. de Weger V, Stuurman FE, Koolen SL, Moes JJ, Hendrikx JJMA, Sawicki E, Thijssen B, Keessen M, Rosing H, Mergui-Roelvink M, Huitema ADR, Nuijen B, Beijnen JH, Schellens JHM, Marchetti S. A phase I dose escalation study of once weekly oral administration of docetaxel as ModraDoc001 capsule or ModraDoc006 tablet in combination with ritonavir. Clin Cancer Res 2019; 25:5466-74 (NKI). 345. de Wit E. Gene Regulation Knows Its Boundaries. Trends Genet 2019; 35:883-5 (NKI). 346. De Wit, M, Kleijnen, M, Lissenberg-Witte, B, Van Uden-Kraan, C, Millet, K, Frambach, R & Verdonck- De Leeuw, I . Understanding drivers of resistance toward implementation of web-based self- management tools in routine cancer care among oncology nurses. Journal of Medical Internet Research 2019;21:12: (Amsterdam UMC). 347. de Witt Hamer, PC, Ho, VKY, Zwinderman, AH, Ackermans, L, Ardon, H, Boomstra, S, Bouwknegt, W, van den Brink, WA, Dirven, CM, van der Gaag, NA, van der Veer, O, Idema, AJS, Kloet, A, Koopmans, J, ter Laan, M, Verstegen, MJT, Wagemakers, M, Robe, PAJT & on behalf of the Quality Registry Neuro Surgery glioblastoma working group from the Dutch Society of Neurosurgery . Between- hospital variation in mortality and survival after glioblastoma surgery in the Dutch Quality Registry for Neuro Surgery. Journal of Neuro-Oncology 2019;144:2:313-323 (Amsterdam UMC). 348. Deenen, NJ, Koens, L, Jaspars, EH, Vermeer, MH, Willemze, R, de Rie, MA & Bekkenk, MW . Pitfalls in diagnosing primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma. British journal of dermatology 2019;180:2:411-412 (Amsterdam UMC). 349. Degens JHRJ, Sanders KJC, de Jong EEC, Groen HJM, Smit EF, Aerts JG, Schols AMWJ, Dingemans AC. The prognostic value of early onset, CT derived loss of muscle and adipose tissue during chemotherapy in metastatic non-small cell lung cancer. Lung Cancer 2019; 133:130-5 (NKI). 350. Dekker, E & Kiesslich, R . Advanced imaging: The impressive success story of gastrointestinal endoscopy. Endoscopy 2019;51:3:209-211 (Amsterdam UMC). 351. Dekker, E, Tanis, PJ, Vleugels, JLA, Kasi, PM & Wallace, MB . Colorectal cancer. Lancet 2019;394:10207:1467-1480 (Amsterdam UMC). 352. Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Migliaccio A, Vermeulen M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L. BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition. Cell Death Dis 2019; 10:338 (14 pp) (NKI). 353. Delli Pizzi A, Caposiena D, Mastrodicasa D, Trebeschi S, Lambregts D, Rosa C, Cianci R, Seccia B, Sessa B, Di Flamminio FM, Chiacchiaretta P, Caravatta L, Cinalli S, Di Sebastiano P, Caulo M, Genovesi D, Beets-Tan R, Basilico R. Tumor detectability and conspicuity comparison of standard b1000 and ultrahigh b2000 diffusion-weighted imaging in rectal cancer. Abdom Radiol (NY) 2019; 44:3595-2605 (NKI). 354. Delli Pizzi A, Tavoletta A, Narciso R, Mastrodicasa D, Trebeschi S, Celentano C, Mastracchio J, Cianci R, Seccia B, Marrone L, Liberati M, Cotroneo AR, Caulo M, Basilico R. Prenatal planning of placenta previa: diagnostic accuracy of a novel MRI-based prediction model for placenta accreta spectrum (PAS) and clinical outcome. Abdom Radiol (NY) 2019; 44:1873-82 (NKI). 355. den Bakker, CM, Huirne, JA, Schaafsma, FG, de Geus, C, Bonjer, HJ & Anema, JR . Electronic Health Program to Empower Patients in Returning to Normal Activities After Colorectal Surgical Procedures: Mixed-Methods Process Evaluation Alongside a Randomized Controlled Trial. Journal of Medical Internet Research 2019;21:1: (Amsterdam UMC). 356. den Bakker, CM, Schaafsma, FG, van der Meij, E, Meijerink, WJ, van den Heuvel, B, Baan, AH, Davids, PH, Scholten, PC, van der Meij, S, van Baal, WM, van Dalsen, AD, Lips, DJ, van der Steeg, JW, Leclercq, WK, Geomini, PM, Consten, EC, Schraffordt Koops, SE, de Castro, SM, van Kesteren, PJ, Cense, HA, Stockmann, HB, ten Cate, AD, Bonjer, HJ, Huirne, JA & Anema, JR . Electronic Health Program to Empower Patients in Returning to Normal Activities After General Surgical and Gynecological Procedures: Intervention Mapping as a Useful Method for Further Development. Journal of Medical Internet Research 2019;21:2: (Amsterdam UMC). 357. den Toom, IJ, Boeve, K, van Weert, S, Bloemena, E, Brouwers, AH, Hoekstra, OS, de Keizer, B, van der Vegt, B, Willems, SM, Leemans, CR, Witjes, MJH & de Bree, R . High rate of unexpected lymphatic drainage patterns and a high accuracy of the sentinel lymph node biopsy in oral cancer after previous neck treatment. Oral Oncology 2019;94::68-72. (Amsterdam UMC). 358. den Toom, IJ, Janssen, LM, van Es, RJJ, Karagozoglu, KH, de Keizer, B, van Weert, S, Willems, SM, Bloemena, E, Leemans, CR & de Bree, R . Depth of invasion in patients with early stage oral cancer staged by sentinel node biopsy. Head and Neck 2019;41:7:2100-2106 (Amsterdam UMC). 359. den Uil SH, van den Broek E, Coupe VMH, Vellinga TT, Delis-Van Diemen PM, Bril H, Belt EJT, Kranenburg O, Stockmann HBAC, Belien JAM, Meijer GA, Fijneman RJA. Prognostic value of microvessel density in stage II and III colon cancer patients: a retrospective cohort study. BMC Gastroenterol 2019; 19:146 (Amsterdam UMC & NKI). 360. Deng, R, Gibiansky, L, Lu, T, Agarwal, P, Ding, H, Li, X, Kshirsagar, S, Lu, D, Li, C, Girish, S, Wang, J, Boyer, M, Humphrey, K, Freise, KJ, Salem, AH, Seymour, JF, Kater, AP & Miles, D . Bayesian Population Model of the Pharmacokinetics of Venetoclax in Combination with Rituximab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Results from the Phase III MURANO Study. Clinical pharmacokinetics 2019;58:12:1621-1634 (Amsterdam UMC). 361. Derks, J, Kulik, S, Wesseling, P, Numan, T, Hillebrand, A, van Dellen, E, Hamer, PCDW, Geurts, JJG, Reijneveld, JC, Stam, CJ, Klein, M & Douw, L . Understanding cognitive functioning in glioma patients. Brain and Behavior 2019;9:4: (Amsterdam UMC). 362. Derksen, JWG, Kurk, SA, Oskam, MJ, Peeters, PHM, Punt, CJA, Koopman, M & May, AM . Factors Contributing to Cancer-Related Muscle Wasting During First-Line Systemic Treatment for Metastatic Colorectal Cancer. JNCI cancer spectrum 2019;3:2:pkz014 (Amsterdam UMC). 363. Deshantri, AK, Fens, MH, Ruiter, RWJ, Metselaar, JM, Storm, G, van Bloois, L, Varela-Moreira, A, Mandhane, SN, Mutis, T, Martens, ACM, Groen, RWJ & Schiffelers, RM . Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma. Journal of Controlled Release 2019;296::232-240. (Amsterdam UMC). 364. deSouza, NM, Achten, E, Alberich-Bayarri, A, Bamberg, F, Boellaard, R, Clément, O, Fournier, L, Gallagher, F, Golay, X, Heussel, CP, Jackson, EF, Manniesing, R, Mayerhofer, ME, Neri, E, O’Connor, J, Oguz, KK, Persson, A, Smits, M, van Beek, EJR, Zech, CJ & European Society of Radiology . Validated imaging biomarkers as decision-making tools in clinical trials and routine practice: current status and recommendations from the EIBALL* subcommittee of the European Society of Radiology (ESR). Insights into Imaging 2019;10:1: (Amsterdam UMC). 365. Detering R, Karthaus EG, Borstlap WAA, Marijnen CAM, van de Velde CJH, Bemelman WA, Beets GL, Tanis PJ, Aalbers AGJ, Dutch Snapshot Research Group., Collaborators (184). Treatment and survival of locally recurrent rectal cancer: A cross-sectional population study 15 years after the Dutch TME trial. Eur J Surg Oncol 2019; 45:2059-69 (Amsterdam UMC & NKI). 366. Detering, R, Borstlap, WAA, Broeders, L, Hermus, L, Marijnen, CAM, Beets-Tan, RGH, Bemelman, WA, van Westreenen, HL, Tanis, PJ & Dutch Snapshot Research Group . Cross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes. Annals of Surgical Oncology 2019;26:2:437-448 (Amsterdam UMC & NKI). 367. Detering, R, Saraste, D, de Neree tot Babberich, MPM, Dekker, JWT, Wouters, MWJM, van Geloven, AAW, Bemelman, WA, Tanis, PJ, Martling, A, Westerterp, M, the Swedish ColoRectal Cancer Registry and the Dutch ColoRectal Audit, Aalbers, A, Beets-Tan, R, Boer, FD, Breukink, S, Coene, PP, Doornebosch, P, Gelderblom, H, Karsten, T, Ledeboer, M, Manusama, E, Marijnen, C, Nagtegaal, I, Peeters, K, Tollenaar, R, Velde, CVD, Wagner, A & Westreenen, EV . International evaluation of circumferential resection margins after rectal cancer resection: insights from the Swedish and Dutch audits. Colorectal disease 2019 (Amsterdam UMC). 368. Dharadhar S, Kim RQ, Uckelmann M, Sixma TK. Quantitative analysis of USP activity in vitro. Methods Enzymol 2019; 618:281-319 (NKI). 369. Di Lorenzo B, Simoes AE, Caiado F, Tieppo P, Correia DV, Carvalho T, da Silva MG, Dechanet-Merville J, Schumacher TN, Prinz I, Norell H, Ravens S, Vermijlen D, Silva-Santos B. Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells. Cancer Immunol Res 2019; 7:552-8 (NKI). 370. Dick, S, Kremer, WW, De Strooper, LMA, Lissenberg-Witte, BI, Steenbergen, RDM, Meijer, CJLM, Berkhof, J & Heideman, DAM . Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis. Gynecologic Oncology 2019;154:2:368-373 (Amsterdam UMC). 371. Dickhoff, C & Dahele, M . The multidisciplinary lung cancer team meeting: Increasing evidence that it should be considered a medical intervention in its own right. Journal of Thoracic Disease 2019;11::S311-S314. (Amsterdam UMC). 372. Dickson, EA, Penna, M, Cunningham, C, Ratcliffe, FM, Chantler, J, Crabtree, NA, Tuynman, JB, Albert, MR, Monson, JRT, Hompes, R, International TaTME Registry Collaborative, Abdelmoaty, W, Adamina, M, Aigner, F, Alavi, K, Albers, B, Albert, M, Al Furajii, H, Allison, A, Alonso Araujo, SE, Apostolides, GY, Arezzo, A, Arnold, SJ, Aryal, K, Ashamalla, S, Ashraf, S, Attaluri, V, Austin, R, Barugola, G, Beggs, A, Belgers, HJ, Bell, S, Bemelman, W, Berti, S, Biebl, M, Blondeel, J, Binky, B, Baloyiannis, I, Bandyopadhyay, D, Boni, L, Bordeianou, L, Box, B, Boyce, S, Brokelman, W, Brown, CJ, Bruegger, L, Buchli, C, Buchs, NC, Bulut, O, Burt, C & Bursics, A . Carbon Dioxide Embolism Associated With Transanal Total Mesorectal Excision Surgery: A Report From the International Registries. Diseases of the colon and rectum 2019;62:7:794-801 (Amsterdam UMC). 373. Dijkgraaf, FE, Matos, TR, Hoogenboezem, M, Toebes, M, Vredevoogd, DW, Mertz, M, van den Broek, B, Song, J-Y, Teunissen, MBM, Luiten, RM, Beltman, JB & Schumacher, TN . Tissue patrol by resident memory CD8+ T cells in human skin. Nature immunology 2019;20:6:756-764 (Amsterdam UMC & NKI). 374. Dijksterhuis, WPM, Pruijt, MJ, van der Woude, SO, Klaassen, R, Kurk, SA, van Oijen, MGH & van Laarhoven, HWM . Association between body composition, survival, and toxicity in advanced esophagogastric cancer patients receiving palliative chemotherapy. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE 2019;10:1:199-206 (Amsterdam UMC). 375. Dijksterhuis, WPM, Stroes, CI, Tan, W-L, Ithimakin, S, Calles, A, van Oijen, MGH, Verhoeven, RHA, Barriuso, J, Oosting, SF, Ivankovic, DK, Furness, AJS, Bozovic-Spasojevic, I, Gomez-Roca, C & van Laarhoven, HWM . From presentation to paper: Gender disparities in oncological research. International journal of cancer. Journal international du cancer 2019 (Amsterdam UMC). 376. Dikmans, REG, van de Grift, TC, Bouman, M-B, Pusic, AL & Mullender, MG . Sexuality, a topic that surgeons should discuss with women before risk-reducing mastectomy and breast reconstruction. Breast 2019;43::120-122. (Amsterdam UMC). 377. Dingemans, A-MC, Hendriks, LEL, Berghmans, T, Levy, A, Hasan, B, Faivre-Finn, C, Giaj-Levra, M, Giaj- Levra, N, Girard, N, Greillier, L, Lantuéjoul, S, Edwards, J, O. Definition of synchronous oligo- metastatic non-small cell lung cancer - a consensus report. Journal of Thoracic Oncology 2019;14:12:2109-2119 (Amsterdam UMC & NKI). 378. Dinis Fernandes C, Ghobadi G, van der Poel HG, de Jong J, Heijmink SWTP, Schoots I, Walraven I, van Houdt PJ, Smolic M, Pos FJ, van der Heide UA. Quantitative 3-T multi-parametric MRI and step- section pathology of recurrent prostate cancer patients after radiation therapy. Eur Radiol 2019; 29:4160-8 (NKI). 379. Dinis Fernandes C, Simoes R, Ghobadi G, Heijmink SW, Schoots IG, de Jong J, Walraven I, van der Poel HG, van Houdt PJ, Smolic M, Pos FJ, van der Heide UA. Multi-parametric MRI tumor probability model for the detection of locally recurrent prostate cancer after radiotherapy: pathological validation and comparison with manual tumor delineations. Int J Radiat Oncol Biol Phys 2019; 105:140-8 (NKI). 380. Dinis Fernandes C, van Houdt PJ, Heijmink SWTP, Walraven I, Keesman R, Smolic M, Ghobadi G, van der Poel HG, Schoots IG, Pos FJ, van der Heide UA. Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy. J Magn Reson Imaging 2019; 50:269-78 (NKI). 381. Dirksen, U, Brennan, B, le Deley, M-CC, Cozic, N, van den Berg, H, Bhadri, V, Brichard, BN, Claude, L, Craft, A, Amler, S, Gaspar, N, Gelderblom, H, Goldsby, R, Gorlick, R, Grier, HE, Guinbretiere, J-M, Hauser, P, Hjorth, L, Janeway, K, Juergens, H, Judson, I, Krailo, M, Kruseova, J, Kuehne, T, Ladenstein, R, Lervat, C, Lessnick, SL, Lewis, I, Linassier, C, Marec-Berard, P, Marina, N, Morland, B, Pacquement, HL, Paulussen, M, Randall, RL, Ranft, A, le Teuff, G, Wheatley, K, Whelan, J, Womer, R, Oberlin, O, Hawkins, DS & Euro-E.W.I.N.G. 99 and Ewing 2008 Investigators . High-Dose Chemotherapy Compared With Standard Chemotherapy and Lung Radiation in Ewing Sarcoma With Pulmonary Metastases: Results of the European Ewing Tumour Working Initiative of National Groups, 99 Trial and EWING 2008. Journal of clinical oncology 2019;37:34:3192-3202 (Amsterdam UMC). 382. Dirven, L, Reijneveld, JC, Taphoorn, MJB, Coens, C, el-Badawy, SA, Tzuk-Shina, T, Bravo-Marques, J, Back, M, Stalpers, LJA, Stupp, R, Baumert, BG & Seidel, C . Impact of Radiation Target Volume on Health-Related Quality of Life in Patients With Low-Grade Glioma in the 2-Year Period Post Treatment: A Secondary Analysis of the EORTC 22033-26033. International journal of radiation oncology, biology, physics 2019;104:1:90-100 (Amsterdam UMC). 383. Disselhorst MJ, Quispel-Janssen J, Lalezari F, Monkhorst K, de Vries JF, van der Noort V, Harms E, Burgers S, Baas P. Ipilimumab and nivolumab in the treatment of recurrent malignant pleural mesothelioma (INITIATE): results of a prospective, single-arm, phase 2 trial. Lancet Respir Med 2019; 7:260-70 (NKI). 384. Dobšíček Trefná, H, Schmidt, M, van Rhoon, GC, Kok, HP, Gordeyev, SS, Lamprecht, U, Marder, D, Nadobny, J, Ghadjar, P, Abdel-Rahman, S, Kukiełka, AM, Strnad, V, Hurwitz, MD, Vujaskovic, Z, Diederich, CJ, Stauffer, PR & Crezee, J . Quality assurance guidelines for interstitial hyperthermia. International journal of hyperthermia 2019;36:1:277-294 (Amsterdam UMC). 385. Dogan-Topal B, Li W, Schinkel AH, Beijnen JH, Sparidans RW. Quantification of FGFR4 inhibitor BLU- 554 in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1110-1111:116-23 (NKI). 386. Dominguez-Escrig JL, Peyronnet B, Seisen T, Bruins HM, Yuan CY, Babjuk M, Bohle A, Burger M, Comperat EM, Gontero P, Lam T, MacLennan S, Mostafid H, Palou J, van Rhijn BWG, Sylvester RJ, Zigeuner R, Shariat SF, Roupret M. Potential Benefit of Lymph Node Dissection During Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the European Association of Urology Guidelines Panel on Non-muscle-invasive Bladder Cancer. Eur Urol Focus 2019; 5:224-41 (NKI). 387. Dong, L, Zieren, RC, Wang, Y, de Reijke, TM, Xue, W & Pienta, KJ . Recent advances in extracellular vesicle research for urological cancers. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 2019;1871:2:342-360 (Amsterdam UMC). 388. Dong, L, Zieren, RC, Xue, W, de Reijke, TM & Pienta, KJ . Metastatic prostate cancer remains incurable, why?. Asian Journal of Urology 2019;6:1:26-41 (Amsterdam UMC). 389. Donovan BT, Huynh A, Ball DA, Patel HP, Poirier MG, Larson DR, Ferguson ML, Lenstra TL. Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting. EMBO J 2019; 38:e100809 (18 pp) (NKI). 390. Doring M, Blees H, Koller N, Tischer-Zimmermann S, Musken M, Henrich F, Becker J, Grabski E, Wang J, Janssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampe R, Kalinke U. Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation. Blood Adv 2019; 3:839-50 (NKI). 391. Dork T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q, Dennis J, Ahearn T, Andrulis IL, nton-Culver H, Arndt V, Aronson KJ, Augustinsson A, Freeman LEB, Beckmann MW, Beeghly-Fadiel A, Behrens S, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Burwinkel B, Canzian F, Chan TL, Chang-Claude J, Chanock SJ, Choi JY, Christiansen H, Clarke CL, Couch FJ, Czene K, Daly MB, Dos-Santos-Silva I, Dwek M, Eccles DM, Ekici AB, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, Gao C, Gapstur SM, Garcia-Closas M, Garcia- Saenz JA, Gaudet MM, Giles GG, Goldberg MS, Goldgar DE, Guenel P, Haeberle L, Haiman CA, Hakansson N, Hall P, Hamann U, Hartman M, Hauke J, Hein A, Hillemanns P, Hogervorst FBL, Hooning MJ, Hopper JL, Howell T, Huo D, Ito H, Iwasaki M, Jakubowska A, Janni W, John EM, Jung A, Kaaks R, Kang D, Kapoor PM, Khusnutdinova E, Kim SW, Kitahara CM, Koutros S, Kraft P, Kristensen VN, Kwong A, Lambrechts D, Marchand LL, Li J, Lindstrom S, Linet M, Lo WY, Long J, Lophatananon A, Lubinski J, Manoochehri M, Manoukian S, Margolin S, Martinez E, Matsuo K, Mavroudis D, Meindl A, Menon U, Milne RL, Mohd Taib NA, Muir K, Mulligan AM, Neuhausen SL, Nevanlinna H, Neven P, Newman WG, Offit K, Olopade OI, Olshan AF, Olson JE, Olsson H, Park SK, Park-Simon TW, Peto J, Plaseska-Karanfilska D, Pohl-Rescigno E, Presneau N, Rack B, Radice P, Rashid MU, Rennert G, Rennert HS, Romero A, Ruebner M, Saloustros E, Schmidt MK, Schmutzler RK, Schneider MO, Schoemaker MJ, Scott C, Shen CY, Shu XO, Simard J, Slager S, Smichkoska S, Southey MC, Spinelli JJ, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper WJ, Teo SH, Terry MB, Toland AE, Tollenaar RAEM, Torres D, Torres-Mejia G, Troester MA, Truong T, Tsugane S, Untch M, Vachon CM, Ouweland AMWV, Veen EMV, Vijai J, Wendt C, Wolk A, Yu JC, Zheng W, Ziogas A, Ziv E, Dunning AM, Pharoah PDP, Schindler D, Devilee P, Easton DF. Two truncating variants in FANCC and breast cancer risk. Sci Rep 2019; 9:12524 (14 pp) (NKI). 392. Douma KFL, Bleeker FE, Medendorp NM, Croes EAJ, Smets EMA. Information exchange between patients with Lynch syndrome and their genetic and non-genetic health professionals: whose responsibility? J Community Genet 2019; 10:237-47 . (NKI). 393. Douma, JAJ, Verdonck-de Leeuw, IM, Leemans, CR, Jansen, F, Langendijk, JA, Baatenburg de Jong, RJ, Terhaard, CHJ, Takes, RP, Chinapaw, MJ, Altenburg, TM & Buffart, LM . Demographic, clinical and lifestyle-related correlates of accelerometer assessed physical activity and fitness in newly diagnosed patients with head and neck cancer. Acta Oncologica 2019 (Amsterdam UMC). 394. Douma, LN, Uiters, E & Timmermans, DRM . Do people with a different goal-orientation or specific focus make different decisions about colorectal cancer-screening participation?. PLoS ONE 2019;14:2: (Amsterdam UMC). 395. Draper, EJ, Hillen, MA, Moors, M, Ket, JCF, van Laarhoven, HWM & Henselmans, I . Relationship between physicians’ death anxiety and medical communication and decision-making: A systematic review. Patient education and counseling 2019;102:2:266-274 (Amsterdam UMC). 396. Draulans C, De Roover R, van der Heide UA, Haustermans K, Pos F, Smeenk RJ, De Boer H, Depuydt T, Kunze-Busch M, Isebaert S, Kerkmeijer L. Stereotactic body radiation therapy with optional focal lesion ablative microboost in prostate cancer: Topical review and multicenter consensus. Radiother Oncol 2019; 140:131-42 (NKI). 397. Dreijerink, KMA, Rijken, JA, Compaijen, CJ, Timmers, HJLM, van der Horst-Schrivers, ANA, van Leeuwaarde, RS, van Dam, PS, Leemans, CR, van Dam, EWCM, Dickhoff, C, Dommering, CJ, de Graaf, P, Zwezerijnen, GJC, van der Valk, P, Menke-van der Houven van Oordt, CW, Hensen, EF, Corssmit, EPM & Eekhoff, EMW . Biochemically Silent Sympathetic Paraganglioma, Pheochromocytoma, or Metastatic Disease in SDHD Mutation Carriers. Journal of Clinical Endocrinology and Metabolism 2019;104:11:5421-5426 (Amsterdam UMC). 398. Drent, E, Poels, R, Ruiter, R, van de Donk, NWCJ, Zweegman, S, Yuan, H, de Bruijn, J, Sadelain, M, Lokhorst, HM, Groen, RWJ, Mutis, T & Themeli, M . Combined CD28 and 4-1BB costimulation potentiates affinity-tuned chimeric antigen receptor-engineered t cells. Clinical Cancer Research 2019;25:13:4014-4025 (Amsterdam UMC). 399. Driessen CML, Leijendeckers J, Snik A, van der Graaf WTA, de Boer JP, Gelderblom H, Kaanders JHAM, Takes R, van Herpen CML. Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy. Head Neck 2019; 41:488-94 (NKI). 400. Druet, X, Acosta Sanchez, E, Soleakhena, K, Laprie, A, Sáez, J, Nougaret, S, Riou, O, Rigal, E, Kibranian, L, Palacios, M & Membrive, I . MRI in medical practice and its future use in radiation oncology. Resume of XXV GOCO Congress (Montpellier) 2017. Reports of Practical Oncology and Radiotherapy 2019;24:4:355-362 (Amsterdam UMC). 401. DʼSouza, N, de Neree tot Babberich, MPM, d. Definition of the Rectum: An International, Expert- based Delphi Consensus. Annals of surgery 2019;270:6:955-959 (Amsterdam UMC & NKI). 402. Duetz, C, Westers, TM & van de Loosdrecht, AA . Clinical Implication of Multi-Parameter Flow Cytometry in Myelodysplastic Syndromes. Pathobiology 2019;86:1:14-23 (Amsterdam UMC). 403. Dufresne, J, Bowden, P, Thavarajah, T, Florentinus-Mefailoski, A, Chen, ZZ, Tucholska, M, Norzin, T, Ho, MT, Phan, M, Mohamed, N, Ravandi, A, Stanton, E, Slutsky, AS, Dos Santos, CC, Romaschin, A, Marshall, JC, Addison, C, Malone, S, Heyland, D, Scheltens, P, Killestein, J, Teunissen, C, Diamandis, EP, Siu, KWM & Marshall, JG . The plasma peptides of breast versus ovarian cancer. Clinical Proteomics 2019;16:1: (Amsterdam UMC). 404. Duineveld, LAM, Molthof, H, Wieldraaijer, T, van de Ven, AWH, Busschers, WB, van Weert, HCPM & Wind, J . General practitioners' involvement during survivorship care of colon cancer in the Netherlands: primary health care utilization during survivorship care of colon cancer, a prospective multicentre cohort study. Family practice 2019;36:6:765-770 (Amsterdam UMC). 405. Duinkerken CW, Rohaan MW, de Weger V, Lohuis PJFM, Latenstein MN, Theunissen EAR, Balm AJM, Dreschler WA, Haanen JBAG, Zuur CL. Sensorineural Hearing Loss After Adoptive Cell Immunotherapy for Melanoma Using MART-1 Specific T Cells: A Case Report and Its Pathophysiology. Otol Neurotol 2019; 40:e674-e678 (NKI). 406. Duinkerken, S, Horrevorts, SK, Kalay, H, Ambrosini, M, Rutte, L, de Gruijl, TD, Garcia-Vallejo, JJ & van Kooyk, Y . Glyco-dendrimers as intradermal anti-tumor vaccine targeting multiple skin DC subsets. Theranostics 2019;9:20:5797-5809 (Amsterdam UMC). 407. Duinkerken, S, Li, RJE, van Haften, FJ, de Gruijl, TD, Chiodo, F, Schetters, STT & van Kooyk, Y . Chemically engineered glycan-modified cancer vaccines to mobilize skin dendritic cells. Current Opinion Chemical Biology 2019;53::167-172. (Amsterdam UMC). 408. Duits, LC, Klaver, E, Bureo Gonzalez, A, Boerwinkel, DF, ten Kate, FJW, Offerhaus, GJA, Meijer, SL, Visser, M, Seldenrijk, CA, Krishnadath, KK, Schoon, EJ, Weusten, BLAM, Mallant-Hent, RC, Pouw, RE & Bergman, JJGHM . The Amsterdam ReBus progressor cohort: identification of 165 Barrett's surveillance patients who progressed to early neoplasia and 723 nonprogressor patients. Diseases of the esophagus 2019;32:9: (Amsterdam UMC). 409. Duits, LC, Lao-Sirieix, P, Wolf, WA, O. A biomarker panel predicts progression of Barrett's esophagus to esophageal adenocarcinoma. Diseases of the esophagus 2019;32:1: (Amsterdam UMC). 410. Durmus S, van der Valk M, Teunissen SF, Song JY, Wagenaar E, Beijnen JH, Schinkel AH. ABC transporters Mdr1a/1b, Bcrp1, Mrp2 and Mrp3 determine the sensitivity to PhIP/DSS-induced colon carcinogenesis and inflammation. Arch Toxicol 2019; 93:775-90 (NKI). 411. Dusoswa, SA, Horrevorts, SK, Ambrosini, M, Kalay, H, Paauw, NJ, Nieuwland, R, Pegtel, MD, Würdinger, T, van Kooyk, Y & Garcia-Vallejo, JJ . Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells. Journal of extracellular vesicles 2019;8:1: (Amsterdam UMC). 412. Dusoswa, SA, Verhoeff, J & Garcia-Vallejo, JJ . OMIP-054: Broad Immune Phenotyping of Innate and Adaptive Leukocytes in the Brain, Spleen, and Bone Marrow of an Orthotopic Murine Glioblastoma Model by Mass Cytometry. Cytometry Part B. Clinical Cytometry 2019;95:4:422-426 (Amsterdam UMC). 413. Dutch Benign Liver Tumour Group, van Rosmalen, BV, de Graeff, JJ, van der Poel, MJ, de Man, IE, Besselink, M, Abu Hilal, M, Busch, OR, Verheij, J & van Gulik, TM . Impact of open and minimally invasive resection of symptomatic solid benign liver tumours on symptoms and quality of life. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:9:1119-1130 (Amsterdam UMC). 414. Dutch Colonoscopy Quality Assurance working group, Bronzwaer, MES, Depla, ACTM, van Lelyveld, N, Spanier, BWM, Oosterhout, YH, van Leerdam, ME, Spaander, MCW, Dekker, E, van Haastert, M, Keller, JJ, Koch, AD, Koornstra, JJ, van Kouwen, MCA, Masclee, A, Mundt, MW, de Ridder, RJ, van der Sluys-Veer, A, van Wieren, M, van Haastert, M, Keller, JJ, Koch, AD, Koornstra, JJ, van Kouwen, MCA, Masclee, A, Mundt, MW, de Ridder, RJ, van der Sluys-Veer, A & van Wieren, M . Quality assurance of colonoscopy within the Dutch national colorectal cancer screening program. Gastrointestinal endoscopy 2019;89:1:41275 (Amsterdam UMC). 415. Dutch ColoRectal Cancer Audit Group, Detering, R, Roodbeen, SX, van Oostendorp, SE, Dekker, J-WT, Sietses, C, Bemelman, WA, Tanis, PJ, Hompes, R & Tuynman, JB . Three-Year Nationwide Experience with Transanal Total Mesorectal Excision for Rectal Cancer in the Netherlands: A Propensity Score- Matched Comparison with Conventional Laparoscopic Total Mesorectal Excision. Journal of the American College of Surgeons 2019;228:3:235-244 (Amsterdam UMC). 416. Dutch Pancreatic Cancer Group and DGAV StuDoQ|Pancreas, Mackay, TM, Wellner, UF, van Rijssen, LB, Stoop, TF, Busch, OR, Groot Koerkamp, B, Bausch, D, Petrova, E, Besselink, MG & Keck, T . Variation in pancreatoduodenectomy as delivered in two national audits. British journal of surgery 2019;106:6:747-755 (Amsterdam UMC). 417. Dutch Pancreatic Cancer Group, Daamen, LA, Groot, VP, Intven, MPW, Besselink, MG, Busch, OR, Koerkamp, BG, Mohammad, NH, Hermans, JJ, van Laarhoven, HWM, Nuyttens, JJ, Wilmink, JW, van Santvoort, HC, Molenaar, IQ & Stommel, MWJ . Postoperative surveillance of pancreatic cancer patients. European journal of surgical oncology 2019;45:10:1770-1777 (Amsterdam UMC). 418. Dutch Pancreatic Cancer Group, Linnemann, RJA, Patijn, GA, van Rijssen, LB, Besselink, MG, Mungroop, TH, de Hingh, IH, Kazemier, G, Festen, S, de Jong, KP, van Eijck, CHJ, Scheepers, JJG, van der Kolk, M, Dulk, MD, Bosscha, K, Busch, OR, Boerma, D, van der Harst, E & Nieuwenhuijs, VB . The role of abdominal drainage in pancreatic resection – A multicenter validation study for early drain removal. Pancreatology 2019;19:6:888-896 (Amsterdam UMC). 419. Dutch Pancreatic Cancer Group, Mackay, TM, van Erning, FN, van der Geest, LGM, de Groot, JWB, Haj Mohammad, N, Lemmens, VE, van Laarhoven, HW, Besselink, MG & Wilmink, JW . Association between primary origin (head, body and tail) of metastasised pancreatic ductal adenocarcinoma and oncologic outcome: A population-based analysis. European journal of cancer (Oxford, England 2019;106::99-105. (Amsterdam UMC). 420. Dutch Pancreatic Cancer Group, Mungroop, TH, Klompmaker, S, Groot Koerkamp, B & Besselink, MG . Added Value of Body Fat Distribution in Predicting Clinically Significant Pancreatic Fistula in the a- FRS Following Pancreatoduodenectomy Currently Unclear. Annals of surgery 2019;269:1: (Amsterdam UMC). 421. Dutch Pancreatic Cancer Group, Mungroop, TH, van Rijssen, LB, van Klaveren, D, Smits, FJ, van Woerden, V, Linnemann, RJ, de Pastena, M, Klompmaker, S, Marchegiani, G, Ecker, BL, van Dieren, S, Bonsing, B, Busch, OR, van Dam, RM, Erdmann, J, van Eijck, CH, Gerhards, MF, van Goor, H, van der Harst, E, de Hingh, IH, de Jong, KP, Kazemier, G, Luyer, M, Shamali, A, Barbaro, S, Armstrong, T, Takhar, A, Hamady, Z, Klaase, J, Lips, DJ, Molenaar, IQ, Nieuwenhuijs, VB, Rupert, C, van Santvoort, HC, Scheepers, JJ, van der Schelling, GP, Bassi, C, Vollmer, CM, Steyerberg, EW, Abu Hilal, M, Groot Koerkamp, B & Besselink, MG . Alternative Fistula Risk Score for Pancreatoduodenectomy (a-FRS): Design and International External Validation. Annals of surgery 2019;269:5:937-943 (Amsterdam UMC). 422. Dutch Pancreatic Cancer Group, Scholten, L, Latenstein, AEJ, van Eijck, C, Erdmann, J, van der Harst, E, Mieog, JSD, Molenaar, IQ, van Santvoort, HC, DeVries, JH & Besselink, MG . Outcome and long- term quality of life after total pancreatectomy (PANORAMA): a nationwide cohort study. Surgery 2019;166:6:1017-1026 (Amsterdam UMC). 423. Dutch Pancreatic Cancer Group, van Hilst, J, Brinkman, DJ, de Rooij, T, van Dieren, S, Gerhards, MF, de Hingh, IH, Luyer, MD, Marsman, HA, Karsten, TM, Busch, OR, Festen, S, Heger, M & Besselink, MG . The inflammatory response after laparoscopic and open pancreatoduodenectomy and the association with complications in a multicenter randomized controlled trial. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:11:1453-1461 (Amsterdam UMC). 424. Dutch Pancreatic Cancer Group, van Hilst, J, de Rooij, T, Bosscha, K, Brinkman, DJ, van Dieren, S, Dijkgraaf, MG, Gerhards, MF, de Hingh, IH, Karsten, TM, Lips, DJ, Luyer, MD, Busch, OR, Festen, S, Besselink, MG, Marsman, HA, van Gulik, TM, Wicherts, DA, Eshuis, WJ, Stibbe, LA, Nieveen van Dijkum, EJM, van Hooft, JE, Fockens, P, van Laarhoven, HW, Wilmink, JW, van de Vijver, MJ, Bijlsma, MF, Verheij, J, Nio, CY, van Lienden, KP, van Tienhoven, G, Schoorlemmer, A, Creemers, G-J, van Eijck, CHJ, Groot Koerkamp, B, Bruno, MJ, Eskens, F, Nuyttens, JJ, Pek, C, van der Schelling, GP, Swijnenburg, RJ, Brosens, LA, Roos, D, van Santvoort, HC, Haj Mohammad, N, Daams, F, van Rijssen, LB, van Veldhuisen, E, Scholten, L, Strijker, M & Korrel, M . Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial. lancet. Gastroenterology & hepatology 2019;4:3:199-207 (Amsterdam UMC). 425. Dutch Pancreatic Cancer Group, van Hilst, J, de Rooij, T, van den Boezem, PB, Bosscha, K, Busch, OR, van Duijvendijk, P, Festen, S, Gerhards, MF, de Hingh, IH, Karsten, TM, Kazemier, G, Lips, DJ, Luyer, MD, Nieuwenhuijs, VB, Patijn, GA, Stommel, MW, Zonderhuis, BM, Daams, F & Besselink, MG . Laparoscopic pancreatoduodenectomy with open or laparoscopic reconstruction during the learning curve: a multicenter propensity score matched study. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:7:857-864 (Amsterdam UMC). 426. Dutch Pancreatic Cancer Group, van Veldhuisen, E, Walma, MS, van Rijssen, LB, Busch, OR, Bruijnen, RCG, van Delden, OM, Mohammad, NH, de Hingh, IH, Yo, LS, van Laarhoven, HW, van Leeuwen, MS, Nio, CY, van Santvoort, HC, de Vries, J, Wessels, FJ, Wilmink, JW, Molenaar, IQ, Besselink, MG & van Lienden, KP . Added value of intra-operative ultrasound to determine the resectability of locally advanced pancreatic cancer following FOLFIRINOX chemotherapy (IMAGE): a prospective multicenter study. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:10:1385-1392 (Amsterdam UMC). 427. Dutch Pancreatic Cancer Group, Zwart, MJW, Fuente, I, Hilst, J, de Rooij, T, van Dieren, S, van Rijssen, LB, Schijven, MP, Busch, ORC, Luyer, MD, Lips, DJ, Festen, S, Abu Hilal, M, Besselink, MG, Stibbe, LA & Stibbe, LA . Added value of 3D-vision during laparoscopic biotissue pancreatico- and hepaticojejunostomy (LAELAPS 3D2D): an international randomized cross-over trial. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:8:1087-1094 (Amsterdam UMC). 428. Dutch Pancreatitis Study Group, da Costa, DW, Schepers, NJ, Bouwense, SA, Hollemans, RA, van Santvoort, HC, Bollen, TL, Consten, EC, van Goor, H, Hofker, S, Gooszen, HG, Boerma, D & Besselink, MG . Predicting a ‘difficult cholecystectomy’ after mild gallstone pancreatitis. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:7:827-833 (Amsterdam UMC). 429. Dutch-Belgian Hemato-Oncology Cooperative Group (HOVON), Huls, G, Chitu, DA, Havelange, V, Jongen-Lavrencic, M, van de Loosdrecht, AA, Biemond, BJ, Sinnige, H, Hodossy, B, Graux, C, Kooy, RVM, de Weerdt, O, Breems, D, Klein, S, Kuball, JR, Deeren, D, Terpstra, W, Vekemans, M-C, Ossenkoppele, GJ, Vellenga, E & Löwenberg, B . Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients. Blood 2019;133:13:1457-1464 (Amsterdam UMC). 430. Dziadziuszko, R, Smit, EF, Dafni, U, Wolf, J, Wasąg, B, Biernat, W, Finn, SP, Kammler, R, Tsourti, Z, Rabaglio, M, Ruepp, B, Roschitzki-Voser, H, Stahel, RA, Felip, E & Peters, S . Afatinib in NSCLC With HER2 Mutations: Results of the Prospective, Open-Label Phase II NICHE Trial of European Thoracic Oncology Platform (ETOP). Journal of Thoracic Oncology 2019;14:6:1086-1094 (Amsterdam UMC & NKI). 431. E pSSG Radiology Group, Vaarwerk, B, Bisogno, G, McHugh, K, Brisse, HJ, Morosi, C, Corradini, N, Jenney, M, Orbach, D, Chisholm, JC, Ferrari, A, Zanetti, I, De Salvo, GL, van Rijn, RR & Merks, JHM . Indeterminate Pulmonary Nodules at Diagnosis in Rhabdomyosarcoma. Journal of clinical oncology 2019;37:9:723-730 (Amsterdam UMC). 432. Ebbing, EA, van der Zalm, AP, Steins, A, Creemers, A, Hermsen, S, Rentenaar, R, Klein, M, Waasdorp, C, Hooijer, GKJ, Meijer, SL, Krishnadath, KK, Punt, CJA, van Berge Henegouwen, MI, Gisbertz, SS, van Delden, OM, Hulshof, MCCM, Medema, JP, van Laarhoven, HWM & Bijlsma, MF . Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America 2019;116:6:2237-2242 (Amsterdam UMC). 433. Eby, JM, Smith, AR, Riley, TP, Cosgrove, C, Ankney, CM, Henning, SW, Paulos, CM, Garrett-Mayer, E, Luiten, RM, Nishimura, MI, Baker, BM & le Poole, IC . Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells. Pigment cell & melanoma research 2019;32:1:68-78 (Amsterdam UMC). 434. Eeltink, CM, Incrocci, L, Leeuw, IMV & Zweegman, S . Recommended patient information sheet on the impact of haematopoietic cell transplantation on sexual functioning and sexuality. Ecancermedicalscience 2019;13::987 (Amsterdam UMC). 435. Eerenstein, SEJ, Verdonck-de Leeuw, IM & Leemans, CR . Swallowing and Voice Outcomes following Treatment of Hypopharyngeal Cancer: The Need for Supervised Rehabilitation. Advances in Oto- Rhino-Laryngology 2019;83::118-125 (Amsterdam UMC). 436. Efficace F, Cottone F, Sommer K, Kieffer J, Aaronson N, Fayers P, Groenvold M, Caocci G, Lo Coco F, Gaidano G, Niscola P, Baccarani M, Rosti G, Venditti A, Angelucci E, Fazi P, Vignetti M, Giesinger J. Validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 Summary Score in Patients With Hematologic Malignancies. Value Health 2019; 22:1303-10 (NKI). 437. Egeblad M, de Visser KE. Sticking together helps cancer to spread. Nature 2019; 566:459-60 [Comment] (NKI). 438. Eggermont AMM, Apolone G, Baumann M, Caldas C, Celis JE, de Lorenzo F, Ernberg I, Ringborg U, Rowell J, Tabernero J, Voest E, Calvo F. Cancer Core Europe: A translational research infrastructure for a European mission on cancer. Mol Oncol 2019; 13:521-7 (NKI). 439. Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson VG, Dalle S, Haydon A, Lichinitser M, Khattak A, Carlino MS, Sandhu S, Larkin J, Puig S, Ascierto PA, Rutkowski P, Schadendorf D, Koornstra R, Hernandez-Aya L, Di Giacomo AM, van den Eertwegh AJ, Grob JJ, Gutzmer R, Jamal R, Lorigan PC, Lupinacci R, Krepler C, Ibrahim N, Kicinski M, Marreaud S, van Akkooi AC, Suciu S, Robert C. Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma. Eur J Cancer 2019; 116:148-57 (Amsterdam UMC & NKI). 440. Eijgelaar R, De Witt Hamer PC, Peeters CFW, Barkhof F, van Herk M, Witte MG. Voxelwise statistical methods to localize practice variation in brain tumor surgery. PLoS One 2019; 14:e0222939 (Amsterdam UMC & NKI). 441. Eijkelenboom A, Tops BBJ, van den Berg A, van den Brule AJC, Dinjens WNM, Dubbink HJ, Ter Elst A, Geurts-Giele WRR, Groenen PJTA, Groenendijk FH, Heideman DAM, Huibers MMH, Huijsmans CJJ, Jeuken JWM, van Kempen LC, Korpershoek E, Kroeze LI, de Leng WWJ, van Noesel CJM, Speel EM, Vogel MJ, van Wezel T, Nederlof PM, Schuuring E, Ligtenberg MJL. Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics. Virchows Arch 2019; 474:673-80 (Amsterdam UMC & NKI). 442. Ekman S, Griesinger F, Baas P, Chao D, Chouaid C, O'Donnell JC, Penrod JR, Daumont M, Lacoin L, McKenney A, Khovratovich M, Munro RE, Durand-Zaleski I, Johnsen SP. I-O Optimise: a novel multinational real-world research platform in thoracic malignancies. Future Oncol 2019; 15:1551-63 (NKI). 443. El Amrani M, Donners AAM, Hack CE, Huitema ADR, van Maarseveen EM. Six-step workflow for the quantification of therapeutic monoclonal antibodies in biological matrices with liquid chromatography mass spectrometry - A tutorial. Anal Chim Acta 2019; 1080:22-34 (NKI). 444. el Hassouni, B, Li Petri, G, Liu, DSK, Cascioferro, S, Parrino, B, Hassan, W, Diana, P, Ali, A, Frampton, AE & Giovannetti, E . Pharmacogenetics of treatments for pancreatic cancer. Expert Opinion on Drug Metabolism and Toxicology 2019;15:6:437-447 (Amsterdam UMC). 445. el Hassouni, B, Mantini, G, Immordino, B, Peters, GJ & Giovannetti, E . CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage. Molecules 2019;24:24: (Amsterdam UMC). 446. El Hassouni, B, Mantini, G, Li Petri, G, Capula, M, Boyd, L, Weinstein, HNW, Vallés-Marti, A, Kouwenhoven, MCM, Giovannetti, E, Westerman, BA, Peters, GJ & EORTC PAMM Group . To Combine or Not Combine. Anticancer Research 2019;39:7:3303-3309 (Amsterdam UMC). 447. el Hassouni, B, Sarkisjan, D, Vos, JC, Giovannetti, E & Peters, GJ . Targeting the Ribosome Biogenesis Key Molecule Fibrillarin to Avoid Chemoresistance. Current Medicinal Chemistry 2019;26:33:6020- 6032 (Amsterdam UMC). 448. Elbatsh AMO, Kim E, Eeftens JM, Raaijmakers JA, van der Weide RH, Garcia-Nieto A, Bravo S, Ganji M, Uit de Bos J, Teunissen H, Medema RH, de Wit E, Haering CH, Dekker C, Rowland BD. Distinct Roles for Condensin's Two ATPase Sites in Chromosome Condensation. Mol Cell 2019; 76:724-37 (NKI). 449. Elbers JBW, Al-Mamgani A, van den Brekel MWM, Jozwiak K, de Boer JP, Lohuis PJFM, Willems SM, Verheij M, Zuur CL. Salvage Surgery for Recurrence after Radiotherapy for Squamous Cell Carcinoma of the Head and Neck. Otolaryngol Head Neck Surg 2019; 160:1023-33 (Amsterdam UMC & NKI). 450. Elbers JBW, Veldhuis LI, Bhairosing PA, Smeele LE, Jozwiak K, van den Brekel MWM, Verheij M, Al- Mamgani A, Zuur CL. Salvage surgery for advanced stage head and neck squamous cell carcinoma following radiotherapy or chemoradiation. Eur Arch Otorhinolaryngol 2019; 276:647-55 (Amsterdam UMC &NKI). 451. Elfrink, S, de Winde, CM, van den Brand, M, Berendsen, M, Roemer, MGM, Arnold, F, Janssen, L, van der Schaaf, A, Jansen, E, Groenen, PJTA, Eijkelenboom, A, Stevens, W, Hess, CJ, van Krieken, JH, Vermaat, JSP, Cleven, AHG, de Groen, RAL, Neviani, V, de Jong, D, van Deventer, S, Scheijen, B & van Spriel, AB . High frequency of inactivating tetraspanin CD37 mutations in diffuse large B-cell lymphoma at immune-privileged sites. Blood 2019;134:12:946-950 (Amsterdam UMC). 452. Elhalawani, H, Elgohari, B, Lin, TA, Mohamed, ASR, Fitzgerald, TJ, Laurie, F, Ulin, K, Kalpathy-Cramer, J, Guerrero, T, Holliday, EB, Russo, G, Patel, A, Jones, W, Walker, GV, Awan, M, Choi, M, Dagan, R, Mahmoud, O, Shapiro, A, Kong, F-MS, Gomez, D, Zeng, J, Decker, R, Spoelstra, FOB, Gaspar, LE, Kachnic, LA, Thomas, CR, Okunieff, P & Fuller, CD . An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting. Clinical and Translational Radiation Oncology 2019;15::83-92. (Amsterdam UMC). 453. el-Khouly, FE, Veldhuijzen van Zanten, SEM, Santa-Maria Lopez, V, Hendrikse, NH, Kaspers, GJL, Loizos, G, Sumerauer, D, Nysom, K, Pruunsild, K, Pentikainen, V, Thorarinsdottir, HK, Rutkauskiene, G, Calvagna, V, Drogosiewicz, M, Dragomir, M, Deak, L, Kitanovski, L, von Bueren, AO, Kebudi, R, Slavc, I, Jacobs, S, Jadrijevic-Cvrlje, F, Entz-Werle, N, Grill, J, Kattamis, A, Hauser, P, Pears, J, Biassoni, V, Massimino, M, Lopez Aguilar, E, Torsvik, IK, Joao Gil-da-Costa, M, Kumirova, E, Cruz-Martinez, O, Holm, S, Bailey, S, Hayden, T, Thomale, UW, Janssens, GOR, Kramm, CM & van Vuurden, DG . Diagnostics and treatment of diffuse intrinsic pontine glioma. Journal of Neuro-Oncology 2019;145:1:177-184 (Amsterdam UMC). 454. Elming, PB, Sørensen, BS, Oei, AL, Franken, NAP, Crezee, J, Overgaard, J & Horsman, MR . Hyperthermia. Cancers 2019;11:1: (Amsterdam UMC). 455. ENETS 2016 Munich Advisory Board Participants, Baudin, E, Hayes, AR, Scoazec, J-Y, Filosso, PL, Lim, E, Kaltsas, G, Frilling, A, Chen, J, Kos-Kudła, B, Gorbunova, V, Wiedenmann, B, Nieveen van Dijkum, E, Ćwikła, JB, Falkerby, J, Valle, JW, Kulke, MH & Caplin, ME . Unmet Medical Needs in Pulmonary Neuroendocrine (Carcinoid) Neoplasms. Neuroendocrinology 2019;108:1:42917 (Amsterdam UMC). 456. Engbersen MP, Van 't Sant I, Lok C, Lambregts DMJ, Sonke GS, Beets-Tan RGH, van Driel WJ, Lahaye MJ. MRI with diffusion-weighted imaging to predict feasibility of complete cytoreduction with the peritoneal cancer index (PCI) in advanced stage ovarian cancer patients. Eur J Radiol 2019; 114:146- 51 (NKI). 457. ENITEC-consortium, Reijnen, C, van Weelden, WJ, Arts, MSJP, Peters, JP, Rijken, PF, van de Vijver, K, Santacana, M, Bronsert, P, Bulten, J, Hirschfeld, M, Colas, E, Gil-Moreno, A, Reques, A, Mancebo, G, Krakstad, C, Trovik, J, Haldorsen, IS, Huvila, J, Koskas, M, Weinberger, V, Minar, L, Jandakova, E, Snijders, MPLM, van den Berg-van Erp, S, Küsters-Vandevelde, HVN, Matias-Guiu, X, Amant, F, Massuger, LFAG, Bussink, J & Pijnenborg, JMA . Poor outcome in hypoxic endometrial carcinoma is related to vascular density. British journal of cancer 2019;120:11:1037-1044 (Amsterdam UMC). 458. EORTC Quality of Life Group and the EORTC Brain Tumor Group . The added value of health-related quality of life as a prognostic indicator of overall survival and progression-free survival in glioma patients. European Journal of Cancer 2019;116::190-198. (Amsterdam UMC). 459. ERIC, the European Research Initiative on CLL, Baliakas, P, Jeromin, S, Iskas, M, Puiggros, A, Plevova, K, Nguyen-Khac, F, Davis, Z, Rigolin, GM, Visentin, A, Xochelli, A, Delgado, J, Baran-Marszak, F, Stalika, E, Abrisqueta, P, Durechova, K, Papaioannou, G, Eclache, V, Dimou, M, Iliakis, T, Collado, R, Doubek, M, Calasanz, MJ, Ruiz-Xiville, N, Moreno, C, Jarosova, M, Leeksma, AC, Panayiotidis, P, Podgornik, H, Cymbalista, F, Anagnostopoulos, A, Trentin, L, Stavroyianni, N, Davi, F, Ghia, P, Kater, AP, Cuneo, A, Pospisilova, S, Espinet, B, Athanasiadou, A, Oscier, D, Haferlach, C & Stamatopoulos, K . Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact. Blood 2019;133:11:1205-1216 (Amsterdam UMC). 460. Eriksson AG, Fallaas DG, Nesbakken AJ, Lund KV, Amant F. Endometrial cancer during pregnancy: management strategies. Int J Gynecol Cancer 2019; 29:1221-4 (NKI). 461. Eriksson, AG, Fallaas Dahl, G, Nesbakken, A-J, Lund, KV & Amant, F . Endometrial cancer during pregnancy: Management strategies. International journal of gynecological cancer 2019;29:7:1221- 1224 (Amsterdam UMC). 462. Erozenci, LA, Böttger, F, Bijnsdorp, IV & Jimenez, CR . Urinary exosomal proteins as (pan-)cancer biomarkers: insights from the proteome. FEBS Letters 2019;593:13:1580-1597 (Amsterdam UMC). 463. Escala-Garcia M, Guo Q, Dork T, Canisius S, Keeman R, Dennis J, Beesley J, Lecarpentier J, Bolla MK, Wang Q, Abraham J, Andrulis IL, nton-Culver H, Arndt V, Auer PL, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Boeckx B, Bojesen SE, Bonanni B, Borresen-Dale AL, Brauch H, Brenner H, Brentnall A, Brinton L, Broberg P, Brock IW, Brucker SY, Burwinkel B, Caldas C, Caldes T, Campa D, Canzian F, Carracedo A, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Cheng TD, Chin SF, Clarke CL, Cordina-Duverger E, Couch FJ, Cox DG, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dunn JA, Dunning AM, Durcan L, Dwek M, Earl HM, Ekici AB, Eliassen AH, Ellberg C, Engel C, Eriksson M, Evans DG, Figueroa J, Flesch-Janys D, Flyger H, Gabrielson M, Gago-Dominguez M, Galle E, Gapstur SM, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, George A, Georgoulias V, Giles GG, Glendon G, Goldgar DE, Gonzalez-Neira A, Alnaes GIG, Grip M, Guenel P, Haeberle L, Hahnen E, Haiman CA, Hakansson N, Hall P, Hamann U, Hankinson S, Harkness EF, Harrington PA, Hart SN, Hartikainen JM, Hein A, Hillemanns P, Hiller L, Holleczek B, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Howell A, Huang G, Humphreys K, Hunter DJ, Janni W, John EM, Jones ME, Jukkola-Vuorinen A, Jung A, Kaaks R, Kabisch M, Kaczmarek K, Kerin MJ, Khan S, Khusnutdinova E, Kiiski JI, Kitahara CM, Knight JA, Ko YD, Koppert LB, Kosma VM, Kraft P, Kristensen VN, Kruger U, Kuhl T, Lambrechts D, Le Marchand L, Lee E, Lejbkowicz F, Li L, Lindblom A, Lindstrom S, Linet M, Lissowska J, Lo WY, Loibl S, Lubinski J, Lux MP, MacInnis RJ, Maierthaler M, Maishman T, Makalic E, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martinez ME, Mavroudis D, McLean C, Meindl A, Middha P, Miller N, Milne RL, Moreno F, Mulligan AM, Mulot C, Nassir R, Neuhausen SL, Newman WT, Nielsen SF, Nordestgaard BG, Norman A, Olsson H, Orr N, Pankratz VS, Park-Simon TW, Perez JIA, Perez-Barrios C, Peterlongo P, Petridis C, Pinchev M, Prajzendanc K, Prentice R, Presneau N, Prokofieva D, Pylkas K, Rack B, Radice P, Ramachandran D, Rennert G, Rennert HS, Rhenius V, Romero A, Roylance R, Saloustros E, Sawyer EJ, Schmidt DF, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Schumacher F, Schwentner L, Scott RJ, Scott C, Seynaeve C, Shah M, Simard J, Smeets A, Sohn C, Southey MC, Swerdlow AJ, Talhouk A, Tamimi RM, Tapper WJ, Teixeira MR, Tengstrom M, Terry MB, Thone K, Tollenaar RAEM, Tomlinson I, Torres D, Truong T, Turman C, Turnbull C, Ulmer HU, Untch M, Vachon C, van Asperen CJ, van den Ouweland AMW, van Veen EM, Wendt C, Whittemore AS, Willett W, Winqvist R, Wolk A, Yang XR, Zhang Y, Easton DF, Fasching PA, Nevanlinna H, Eccles DM, Pharoah PDP, Schmidt MK. Genome-wide association study of germline variants and breast cancer-specific mortality. Br J Cancer 2019; 120:647-57 (NKI). 464. Escudier B, Porta C, Schmidinger M, Rioux-Leclercq N, Bex A, Khoo V, Grunwald V, Gillessen S, Horwich A. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-updagger. Ann Oncol 2019; 30:706-20 (NKI). 465. Eskes, AM, Schreuder, AM, Vermeulen, H, Nieveen van Dijkum, EJM & Chaboyer, W . Developing an evidence-based and theory informed intervention to involve families in patients care after surgery: A quality improvement project. International Journal of Nursing Sciences 2019;6:4:352-361 (Amsterdam UMC). 466. Esser, P, Götze, H, Mehnert-Theuerkauf, A, Knoop, H & Kuba, K . Fear of progression and its role in the relationship of cancer-related fatigue with physical functioning and global quality of life – A register-based study among hematological cancer survivors. Journal of psychosomatic research 2019;127:109844: (Amsterdam UMC). 467. Essers PBM, van der Heijden M, Verhagen CVM, Ploeg EM, de Roest RH, Leemans CR, Brakenhoff RH, van den Brekel MWM, Bartelink H, Verheij M, Vens C. Drug sensitivity prediction models reveal a link between DNA repair defects and poor prognosis in HNSCC. Cancer Res 2019; 79:5597-611 (Amsterdam UMC & NKI). 468. European Consortium on Minimally Invasive Pancreatic Surgery (E-MIPS), van Hilst, J, de Rooij, T, Klompmaker, S, Rawashdeh, M, Aleotti, F, Al-Sarireh, B, Alseidi, A, Ateeb, Z, Balzano, G, Berrevoet, F, Björnsson, B, Boggi, U, Busch, OR, Butturini, G, Casadei, R, del Chiaro, M, Chikhladze, S, Cipriani, F, van Dam, R, Damoli, I, van Dieren, S, Dokmak, S, Edwin, B, van Eijck, C, Fabre, J-M, Falconi, M, Farges, O, Fernández-Cruz, L, Forgione, A, Frigerio, I, Fuks, D, Gavazzi, F, Gayet, B, Giardino, A, Groot Koerkamp, B, Hackert, T, Hassenpflug, M, Kabir, I, Keck, T, Khatkov, I, Kusar, M, Lombardo, C, Marchegiani, G, Marshall, R, Menon, KV, Montorsi, M, Orville, M, de Pastena, M, Pietrabissa, A, Besselink, MG & Abu Hilal, M . Minimally Invasive versus Open Distal Pancreatectomy for Ductal Adenocarcinoma (DIPLOMA): A Pan-European Propensity Score Matched Study. Annals of surgery 2019;269:1:43009 (Amsterdam UMC). 469. European paediatric Soft tissue sarcoma Study Group, Bisogno, G, de Salvo, GL, Bergeron, C, Gallego Melcón, S, Merks, JH, Kelsey, A, Martelli, H, Minard-Colin, V, Orbach, D, Glosli, H, Chisholm, J, Casanova, M, Zanetti, I, Devalck, C, Ben-Arush, M, Mudry, P, Ferman, S, Jenney, M & Ferrari, A . Vinorelbine and continuous low-dose cyclophosphamide as maintenance chemotherapy in patients with high-risk rhabdomyosarcoma (RMS 2005): a multicentre, open-label, randomised, phase 3 trial. lancet oncology 2019;20:11:1566-1575 (Amsterdam UMC). 470. Faiz Z, van Putten M, Verhoeven RHA, van Sandick JW, Nieuwenhuijzen GAP, van der Sangen MJC, Lemmens VEPP, Wijnhoven BPL, Plukker JTM. Impact of Age and Comorbidity on Choice and Outcome of Two Different Treatment Options for Patients with Potentially Curable Esophageal Cancer. Ann Surg Oncol 2019; 26:986-95 (NKI). 471. Faria, AVDS, Akyala, AI, Parikh, K, Brüggemann, LW, Spek, CA, Cao, W, Bruno, MJ, Bijlsma, MF, Fuhler, GM & Peppelenbosch, MP . Smoothened-dependent and -independent pathways in mammalian noncanonical Hedgehog signaling. Journal of biological chemistry 2019;294:25:9787- 9798 (Amsterdam UMC). 472. Fast M, van de Schoot A, van de Lindt T, Carbaat C, van der Heide U, Sonke JJ. Tumor trailing for liver SBRT on the MR-Linac. Int J Radiat Oncol Biol Phys 2019; 103:468-78 (NKI). 473. Favie LMA, Groenendaal F, van den Broek MPH, Rademaker CMA, de Haan TR, van Straaten HLM, Dijk PH, van Heijst A, Dudink J, Dijkman KP, Rijken M, Zonnenberg IA, Cools F, Zecic A, van der Lee JH, Nuytemans DHGM, van Bel F, Egberts TCG, Huitema ADR, PharmaCool study group. Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia. PLoS One 2019; 14:e0211910 (NKI). 474. Favie LMA, Groenendaal F, van den Broek MPH, Rademaker CMA, de Haan TR, van Straaten HLM, Dijk PH, van Heijst A, Simons SHP, Dijkman KP, Rijken M, Zonnenberg IA, Cools F, Zecic A, van der Lee JH, Nuytemans DHGM, van Bel F, Egberts TCG, Huitema ADR, on behalf of the PharmaCool study group. Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia. Neonatology 2019; 116:154-62 (NKI). 475. Fegrachi, S, Walma, MS, de Vries, JJJ, van Santvoort, HC, Besselink, MG, von Asmuth, EG, van Leeuwen, MS, Borel Rinkes, IH, Bruijnen, RC, de Hingh, IH, Klaase, JM, Molenaar, IQ & van Hillegersberg, R . Safety of radiofrequency ablation in patients with locally advanced, unresectable pancreatic cancer: A phase II study. European Journal of Surgical Oncology 2019;45:11:2166-2172 (Amsterdam UMC). 476. Feijen EAML, Font-Gonzalez A, Van der Pal HJH, Kok WEM, Geskus RB, Ronckers CM, Bresters D, van Dalen EC, van Dulmen-den Broeder E, van den Berg MH, van der Heiden-van der Loo M, van den Heuvel-Eibrink MM, van Leeuwen FE, Loonen JJ, Neggers SJCM, Versluys ABB, Tissing WJE, Kremer LCM. Risk and Temporal Changes of Heart Failure Among 5-Year Childhood Cancer Survivors: a DCOG-LATER Study. J Am Heart Assoc 2019; 8:e009122 (NKI). 477. Feijen, EAM, Leisenring, WM, Stratton, KL, Ness, KK, van der Pal, HJH, van Dalen, EC, Armstrong, GT, Aune, GJ, Green, DM, Hudson, MM, Loonen, J, Oeffinger, KC, Robison, LL, Yasui, Y, Kremer, LCM & Chow, EJ . Derivation of Anthracycline and Anthraquinone Equivalence Ratios to Doxorubicin for Late-Onset Cardiotoxicity. JAMA oncology 2019;5:6:864-871 (Amsterdam UMC). 478. Fennell DA, Baas P, Taylor P, Nowak AK, Gilligan D, Nakano T, Pachter JA, Weaver DT, Scherpereel A, Pavlakis N, van Meerbeeck JP, Cedres S, Nolan L, Kindler H, Aerts JGJV. Maintenance Defactinib Versus Placebo After First-Line Chemotherapy in Patients With Merlin-Stratified Pleural Mesothelioma: COMMAND-A Double-Blind, Randomized, Phase II Study. J Clin Oncol 2019; 37:790-8 (NKI). 479. Fennell DA, Taylor P, Gilligan D, Nakano T, Scherpereel A, Pavlakis N, van Meerbeeck JP, Aerts JGJV, Nowak AK, Kindler H, Baas P. Reply to K. Masuda et al(NKI). 480. Feroldi, F, Willemse, J, Davidoiu, V, Gräfe, MGO, van Iperen, DJ, Goorsenberg, AWM, Annema, JT, Daniels, JMA, Bonta, PI & de Boer, JF . In vivo multifunctional optical coherence tomography at the periphery of the lungs. Biomedical Optics Express 2019;10:6:3070-3091 (Amsterdam UMC). 481. Ferreira MA, Gamazon ER, Al-Ejeh F, Aittomaki K, Andrulis IL, Anton-Culver H, Arason A, Arndt V, Aronson KJ, Arun BK, Asseryanis E, Azzollini J, Balmana J, Barnes DR, Barrowdale D, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bialkowska K, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Borg A, Brauch H, Brenner H, Broeks A, Burwinkel B, Caldes T, Caligo MA, Campa D, Campbell I, Canzian F, Carter J, Carter BD, Castelao JE, Chang-Claude J, Chanock SJ, Christiansen H, Chung WK, Claes KBM, Clarke CL, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, de la Haya M, Dennis J, Devilee P, Diez O, Dork T, Dunning AM, Dwek M, Eccles DM, Ejlertsen B, Ellberg C, Engel C, Eriksson M, Fasching PA, Fletcher O, Flyger H, Friedman E, Frost D, Gabrielson M, Gago-Dominguez M, Ganz PA, Gapstur SM, Garber J, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, Gonzalez-Neira A, Greene MH, Gronwald J, Guenel P, Haiman CA, Hall P, Hamann U, He W, Heyworth J, Hogervorst FBL, Hollestelle A, Hoover RN, Hopper JL, Hulick PJ, Humphreys K, Imyanitov EN, Isaacs C, Jakimovska M, Jakubowska A, James PA, Janavicius R, Jankowitz RC, John EM, Johnson N, Joseph V, Karlan BY, Khusnutdinova E, Kiiski JI, Ko YD, Jones ME, Konstantopoulou I, Kristensen VN, Laitman Y, Lambrechts D, Lazaro C, Leslie G, Lester J, Lesueur F, Lindstrom S, Long J, Loud JT, Lubinski J, Makalic E, Mannermaa A, Manoochehri M, Margolin S, Maurer T, Mavroudis D, McGuffog L, Meindl A, Menon U, Michailidou K, Miller A, Montagna M, Moreno F, Moserle L, Mulligan AM, Nathanson KL, Neuhausen SL, Nevanlinna H, Nevelsteen I, Nielsen FC, Nikitina-Zake L, Nussbaum RL, Offit K, Olah E, Olopade OI, Olsson H, Osorio A, Papp J, Park-Simon TW, Parsons MT, Pedersen IS, Peixoto A, Peterlongo P, Pharoah PDP, Plaseska- Karanfilska D, Poppe B, Presneau N, Radice P, Rantala J, Rennert G, Risch HA, Saloustros E, Sanden K, Sawyer EJ, Schmidt MK, Schmutzler RK, Sharma P, Shu XO, Simard J, Singer CF, Soucy P, Southey MC, Spinelli JJ, Spurdle AB, Stone J, Swerdlow AJ, Tapper WJ, Taylor JA, Teixeira MR, Terry MB, Teule A, Thomassen M, Thone K, Thull DL, Tischkowitz M, Toland AE, Torres D, Truong T, Tung N, Vachon CM, van Asperen CJ, van den Ouweland AMW, van Rensburg EJ, Vega A, Viel A, Wang Q, Wappenschmidt B, Weitzel JN, Wendt C, Winqvist R, Yang XR, Yannoukakos D, Ziogas A, Kraft P, Antoniou AC, Zheng W, Easton DF, Milne RL, Beesley J, Chenevix-Trench G. Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer. Nat Commun 2019; 10:1741 (Amsterdam UMC & NKI). 482. Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras SV, Pujol R, Kiiski JI, Muranen TA, Barnes DR, Dennis J, Michailidou K, Bolla MK, Leslie G, Aalfs CM, Adank MA, Adlard J, Agata S, Cadoo K, Agnarsson BA, Ahearn T, Aittomaki K, Ambrosone CB, Andrews L, nton-Culver H, Antonenkova NN, Arndt V, Arnold N, Aronson KJ, Arun BK, Asseryanis E, Auber B, Auvinen P, Azzollini J, Balmana J, Barkardottir RB, Barrowdale D, Barwell J, Beane Freeman LE, Beauparlant CJ, Beckmann MW, Behrens S, Benitez J, Berger R, Bermisheva M, Blanco AM, Blomqvist C, Bogdanova NV, Bojesen A, Bojesen SE, Bonanni B, Borg A, Brady AF, Brauch H, Brenner H, Bruning T, Burwinkel B, Buys SS, Caldes T, Caliebe A, Caligo MA, Campa D, Campbell IG, Canzian F, Castelao JE, Chang-Claude J, Chanock SJ, Claes KBM, Clarke CL, Collavoli A, Conner TA, Cox DG, Cybulski C, Czene K, Daly MB, de la Haya M, Devilee P, Diez O, Ding YC, Dite GS, Ditsch N, Domchek SM, Dorfling CM, Dos-Santos-Silva I, Durda K, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flyger H, Foulkes WD, Friebel TM, Friedman E, Gabrielson M, Gaddam P, Gago- Dominguez M, Gao C, Gapstur SM, Garber J, Garcia-Closas M, Garcia-Saenz JA, Gaudet MM, Gayther SA, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, Guenel P, Gutierrez-Barrera AM, Haeberle L, Haiman CA, Hakansson N, Hall P, Hamann U, Harrington PA, Hein A, Heyworth J, Hillemanns P, Hollestelle A, Hopper JL, Hosgood HD, III, Howell A, Hu C, Hulick PJ, Hunter DJ, Imyanitov EN, Isaacs C, Jakimovska M, Jakubowska A, James P, Janavicius R, Janni W, John EM, Jones ME, Jung A, Kaaks R, Karlan BY, Khusnutdinova E, Kitahara CM, Konstantopoulou I, Koutros S, Kraft P, Lambrechts D, Lazaro C, Le Marchand L, Lester J, Lesueur F, Lilyquist J, Loud JT, Lu KH, Luben RN, Lubinski J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martens JWM, Maurer T, Mavroudis D, Mebirouk N, Meindl A, Menon U, Miller A, Montagna M, Nathanson KL, Neuhausen SL, Newman WG, Nguyen-Dumont T, Nielsen FC, Nielsen S, Nikitina-Zake L, Offit K, Olah E, Olopade OI, Olshan AF, Olson JE, Olsson H, Osorio A, Ottini L, Peissel B, Peixoto A, Peto J, Plaseska-Karanfilska D, Pocza T, Presneau N, Pujana MA, Punie K, Rack B, Rantala J, Rashid MU, Rau-Murthy R, Rennert G, Lejbkowicz F, Rhenius V, Romero A, Rookus MA, Ross EA, Rossing M, Rudaitis V, Ruebner M, Saloustros E, Sanden K, Santamarina M, Scheuner MT, Schmutzler RK, Schneider M, Scott C, Senter L, Shah M, Sharma P, Shu XO, Simard J, Singer CF, Sohn C, Soucy P, Southey MC, Spinelli JJ, Steele L, Stoppa-Lyonnet D, Tapper WJ, Teixeira MR, Terry MB, Thomassen M, Thompson J, Thull DL, Tischkowitz M, Tollenaar RAEM, Torres D, Troester MA, Truong T, Tung N, Untch M, Vachon CM, van Rensburg EJ, van Veen EM, Vega A, Viel A, Wappenschmidt B, Weitzel JN, Wendt C, Wieme G, Wolk A, Yang XR, Zheng W, Ziogas A, Zorn KK, Dunning AM, Lush M, Wang Q, McGuffog L. The FANCM:p. Arg658* truncating variant is associated with risk of triple-negative breast cancer(NKI). 483. Finazzi, T, Palacios, MA, Spoelstra, FOB, Haasbeek, CJA, Bruynzeel, AME, Slotman, BJ, Lagerwaard, FJ & Senan, S . Role of On-Table Plan Adaptation in MR-Guided Ablative Radiation Therapy for Central Lung Tumors. International Journal of Radiation Oncology Biology Physics 2019;104:4:933-941 (Amsterdam UMC). 484. Firuzi, O, Che, PP, el Hassouni, B, Buijs, M, Coppola, S, Löhr, M, Funel, N, Heuchel, R, Carnevale, I, Schmidt, T, Mantini, G, Avan, A, Saso, L, Peters, GJ & Giovannetti, E . Role of c-MET inhibitors in overcoming drug resistance in spheroid models of primary human pancreatic cancer and stellate cells. Cancers (Basel) 2019;11:5: (Amsterdam UMC). 485. Floore, A, Hesselink, A, Oštrbenk, A, Alcaniz, E, Rothe, B, Pedersen, H, Torres Hortal, M, Doorn, S, Quint, W, Petry, KU, Poljak, M, Cuschieri, K, Bonde, J, de Sanjosé, S, Bleeker, M & Heideman, D . Intra- and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test. Journal of clinical laboratory analysis 2019;33:4: (Amsterdam UMC). 486. Fockens, P & Rösch, T . Black and white amid the colors of endoscopy - The march of endoscopic ultrasonography. Endoscopy 2019;51:4:294-295 (Amsterdam UMC). 487. Fojecki, G, Magnusson, A, Traxer, O, Baard, J, Osther, PJRS, Jaremko, G, Seitz, C, Knoll, T, Giusti, G & Brehmer, M . Consultation on UTUC, Stockholm 2018 aspects of diagnosis of upper tract urothelial carcinoma. World journal of urology 2019;37:11:2271-2278 (Amsterdam UMC). 488. Fokkema IFAC, van der Velde KJ, Slofstra MK, Ruivenkamp CAL, Vogel MJ, Pfundt R, Blok MJ, Lekanne Deprez RH, Waisfisz Q, Abbott KM, Sinke RJ, Rahman R, Nijman IJ, de Koning B, Thijs G, Wieskamp N, Moritz RJG, Charbon B, Saris JJ, den Dunnen JT, Laros JFJ, Swertz MA, van Gijn ME. Dutch genome diagnostic laboratories accelerated and improved variant interpretation and increased accuracy by sharing data. Hum Mutat 2019; 40:2230-8 (NKI). 489. Fonollà, R, Scheeve, T, Struyvenberg, MR, Curvers, WL, de Groof, AJ, van der Sommen, F, Schoon, EJ, Bergman, JJGHM & de With, PHN . Ensemble of deep convolutional neural networks for classification of Early Barrett's Neoplasia Using Volumetric laser endomicroscopy. Applied Sciences (Switzerland) 2019;9:11: (Amsterdam UMC). 490. for the Dutch Pancreatic Cancer Group, Strijker, M, Belkouz, A, van der Geest, LG, van Gulik, TM, van Hooft, JE, de Meijer, VE, Haj Mohammad, N, de Reuver, PR, Verheij, J, de Vos-Geelen, J, Wilmink, JW, Groot Koerkamp, B, Klümpen, HJ & Besselink, MG . Treatment and survival of resected and unresected distal cholangiocarcinoma. Acta oncologica (Stockholm, Sweden) 2019;58:7:1048-1055 (Amsterdam UMC). 491. For the Gastrointestinal Oncology Center Amsterdam (GIOCA), Steen, MW, van Vliet, C, Festen, S, Besselink, MG, Gerhards, MF & Busch, OR . Regional oncology network between pancreatic centers safeguards waiting times for pancreatoduodenectomy. Updates in surgery 2019;71:4:645-651 (Amsterdam UMC). 492. Franke V, Berger DMS, Klop WMC, van der Hiel B, van de Wiel BA, Ter Meulen S, Wouters MWJM, van Houdt WJ, van Akkooi ACJ. High Response Rates for T-VEC in Early Metastatic Melanoma (Stage IIIB/C-IVM1a). Int J Cancer 2019; 145:974-8 (NKI). 493. Franke V, van Akkooi ACJ. The extent of surgery for stage III melanoma: how much is appropriate? - Personal view. Lancet Oncol 2019; 20:e167-e174 (NKI). 494. Franke V. Talimogene laherparepvec monotherapy, an elegant alternative to systemic immunotherapy for the treatment of early metastatic melanoma. Br J Dermatol 2019; 181:20-1 (NKI). 495. Franken MG, Leeneman B, Gheorghe M, Uyl-de Groot CA, Haanen JBAG, van Baal PHM. A systematic literature review and network meta-analysis of effectiveness and safety outcomes in advanced melanoma. Eur J Cancer 2019; 123:58-71 (NKI). 496. Franken, LC, Schreuder, AM, Roos, E, van Dieren, S, Busch, OR, Besselink, MG & van Gulik, TM . Morbidity and mortality after major liver resection in patients with perihilar cholangiocarcinoma: A systematic review and meta-analysis. Surgery 2019;165:5:918-928 (Amsterdam UMC). 497. Franken, LC, van der Poel, MJ, Latenstein, AEJ, Zwart, MJ, Roos, E, Busch, OR, Besselink, MG & van Gulik, TM . Minimally invasive surgery for perihilar cholangiocarcinoma: a systematic review. Journal of robotic surgery 2019;13:6:717-727 (Amsterdam UMC). 498. Fransen van de Putte EE, Pos F, Doodeman B, van Rhijn BWG, van der Laan E, Nederlof P, van der Heijden MS, Bloos-van der HJ, Sanders J, Broeks A, Kerst JM, van der Noort V, Horenblas S, Bergman AM. Concurrent Radiotherapy and Panitumumab after Lymph Node Dissection and Induction Chemotherapy for Invasive Bladder Cancer. J Urol 2019; 201:478-85 (NKI). 499. Franssen, LE, Mutis, T, Lokhorst, HM & van de Donk, NWCJ . Immunotherapy in myeloma. THERAPEUTIC ADVANCES IN HEMATOLOGY 2019;10::2040620718822660. (Amsterdam UMC). 500. Franzen N, van Harten WH, Retel VP, Loskill P, van den Eijnden-van Raaij AJM, Ijzerman MJ. Impact of organ-on-a-chip technology on pharmaceutical R&D costs. Drug Discov Today 2019; 24:1720-4 (NKI). 501. Frerichs, KA, Bosman, PWC, Nijhof, IS, Zweegman, S & van de Donk, NWCJ . Cytomegalovirus Reactivation in a Patient With Extensively Pretreated Multiple Myeloma During Daratumumab Treatment. Clinical Lymphoma Myeloma and Leukemia 2019;19:1:e9-e11 (Amsterdam UMC). 502. Freund, J, Buijs, M, Savci Heijink, C, de Bruin, D, Delarosette, J, van Leeuwen, A & Laguna Pes, M . Optical Coherence Tomography in Urologic Oncology: a Comprehensive Review. SN Comprehensive Clinical Medicine 2019;1::67-84. (Amsterdam UMC). 503. Freund, JE, Faber, DJ, Bus, MT, van Leeuwen, TG & de Bruin, DM . Grading upper tract urothelial carcinoma with the attenuation coefficient of in-vivo optical coherence tomography. Lasers in surgery and medicine 2019;51:5:399-406 (Amsterdam UMC). 504. Freund, JE, Legemate, JD, Baard, J, Saeb-Parsy, K, Wiseman, O, Doizi, S, Emiliani, E, Breda, A, Boodt, BJ, van Haarst, EP, Leeflang, MMG & Kamphuis, GM . Upper Tract Urothelial Carcinoma Grade Prediction Based on the Ureteroscopic Appearance: Caution Should be Taken. Urology 2019;132::69- 74. (Amsterdam UMC). 505. Freund, JE, Liem, EIML, Savci-Heijink, CD & de Reijke, TM . Fluorescence in situ hybridization in 1 mL of selective urine for the detection of upper tract urothelial carcinoma: a feasibility study. Medical oncology (Northwood, London, England) 2019;36:1: (Amsterdam UMC). 506. Frigerio, B, Bizzoni, C, Jansen, G, Leamon, CP, Peters, GJ, Low, PS, Matherly, LH & Figini, M . Folate receptors and transporters: Biological role and diagnostic/therapeutic targets in cancer and other diseases. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 2019;38:1: (Amsterdam UMC). 507. Frijstein MM, Lok CAR, Coulter J, van Trommel NE, Ten Kate-Booij MJ, Golfier F, Seckl MJ, Massuger LFAG. Is there uniformity in definitions and treatment of gestational trophoblastic disease in Europe? Int J Gynecol Cancer 2019; 29:108-12 . (NKI). 508. Frijstein MM, Lok CAR, van Trommel NE, Ten Kate-Booij MJ, Massuger LFAG, van Werkhoven E, Kaur B, Tidy JA, Sarwar N, Golfier F, Winter MC, Hancock BW, Seckl MJ. Management and prognostic factors of epithelioid trophoblastic tumors: Results from the International Society for the Study of Trophoblastic Diseases database. Gynecol Oncol 2019; 152:361-7 (NKI). 509. Fuccio, L, Rex, D, Ponchon, T, Frazzoni, L, Dinis-Ribeiro, MR, Bhandari, P, Dekker, E, Pellisè, M, Correale, L, van Hooft, J, Jover, R, Libanio, D, Radaelli, F, Alfieri, S, Bazzoli, F, Senore, C, Regula, J, Seufferlein, T, Rösch, T, Sharma, P, Repici, A & Hassan, C . New and Recurrent Colorectal Cancers After Resection: a Systematic Review and Meta-analysis of Endoscopic Surveillance Studies. Gastroenterology 2019;156:5:1309-1323 (Amsterdam UMC). 510. Fuchs, M, Goergen, H, Kobe, C, Kuhnert, G, Lohri, A, Greil, R, Sasse, S, Topp, MS, Schäfer, E, Hertenstein, B, Soekler, M, Vogelhuber, M, Zijlstra, JM, Keller, UB, Krause, SW, Wilhelm, M, Maschmeyer, G, Thiemer, J, Dührsen, U, Meissner, J, Viardot, A, Eich, H, Baues, C, Diehl, V, Rosenwald, A, Von Tresckow, B, Dietlein, M, Borchmann, P & Engert, A . Positron emission tomography-guided treatment in early-stage favorable Hodgkin lymphoma. Journal of Clinical Oncology 2019;37:31:2835-2845 (Amsterdam UMC). 511. Furumaya, A, van Rosmalen, BV, Takkenberg, RB, van Delden, OM, Dejong, CHC, Verheij, J & van Gulik, TM . Transarterial (Chemo-)Embolization and Lipiodolization for Hepatic Haemangioma. Cardiovascular and interventional radiology 2019;42:6:800-811 (Amsterdam UMC). 512. Gafer H, de Waard Q, Compter A, van den Heuvel M. Rapid regression of neurological symptoms in patients with metastasised ALK+ lung cancer who are treated with lorlatinib: a report of two cases. BMJ Case Rep 2019; 12:e227299 (NKI). 513. Gagelmann, N, Eikema, D-J, Stelljes, M, Beelen, D, de Wreede, L, Mufti, G, Knelange, NS, Niederwieser, D, Friis, LS, Ehninger, G, Nagler, A, Yakoub-Agha, I, Meijer, E, Ljungman, P, Maertens, J, Kanz, L, Lopez-Corral, L, Brecht, A, Craddock, C, Finke, JR, Cornelissen, JJ, Bernasconi, P, Chevallier, P, Sierra, J, Robin, M & Kröger, N . Optimized EBMT transplant-specific risk score in myelodysplastic syndromes after allogeneic stem-cell transplantation. Haematologica 2019;104:5:929-936 (Amsterdam UMC). 514. Gao M, Callari M, Beddowes E, Sammut SJ, Grzelak M, Biggs H, Jones L, Boumertit A, Linn SC, Cortes J, Oliveira M, Baird R, Chin SF, Caldas C. Next Generation-Targeted Amplicon Sequencing (NG-TAS): an optimised protocol and computational pipeline for cost-effective profiling of circulating tumour DNA. Genome Med 2019; 11:1 (NKI). 515. Gao, F, Wang, W, Tan, M, Zhu, L, Zhang, Y, Fessler, E, Vermeulen, L & Wang, X . DeepCC: a novel deep learning-based framework for cancer molecular subtype classification. Oncogenesis 2019;8:9: (Amsterdam UMC). 516. Garlipp, B, Gibbs, P, van Hazel, GA, Jeyarajah, R, Martin, RCG, Bruns, CJ, Lang, H, Manas, DM, Ettorre, GM, Pardo, F, Donckier, V, Benckert, C, van Gulik, TM, Goéré, D, Schoen, M, Pratschke, J, Bechstein, WO, de la Cuesta, AM, Adeyemi, S, Ricke, J & Seidensticker, M . Secondary technical resectability of colorectal cancer liver metastases after chemotherapy with or without selective internal radiotherapy in the randomized SIRFLOX trial. British journal of surgery 2019;106:13:1837-1846 (Amsterdam UMC). 517. Gastroesophageal Metastasectomy Group, Seesing, MFJ, van der Veen, A, Brenkman, HJF, Stockmann, HBAC, Nieuwenhuijzen, GAP, Rosman, C, van den Wildenberg, FJH, van Berge Henegouwen, MI, van Duijvendijk, P, Wijnhoven, BPL, Stoot, JHMB, Lacle, M, Ruurda, JP & van Hillegersberg, R . Resection of hepatic and pulmonary metastasis from metastatic esophageal and gastric cancer: a nationwide study. Diseases of the esophagus 2019;32:12: (Amsterdam UMC). 518. Gaunt, T, D’Arco, F, Smets, AM, McHugh, K & Shelmerdine, SC . Emergency imaging in paediatric oncology: a pictorial review. Insights into imaging 2019;10:1: (Amsterdam UMC). 519. Gavazzi, S, van den Berg, CAT, Sbrizzi, A, Kok, HP, Stalpers, LJA, Lagendijk, JJW, Crezee, H & van Lier, ALHMW . Accuracy and precision of electrical permittivity mapping at 3T: the impact of three B1+ mapping techniques. Magnetic resonance in medicine 2019;81:6:3628-3642 (Amsterdam UMC). 520. Geersing, A, de Vries, RH, Jansen, G, Rots, MG & Roelfes, G . Folic acid conjugates of a bleomycin mimic for selective targeting of folate receptor positive cancer cells. Bioorganic and Medicinal Chemistry Letters 2019;29:15:1922-1927 (Amsterdam UMC). 521. Geeurickx, E, Tulkens, J, Dhondt, B, van Deun, J, Lippens, L, Vergauwen, G, Heyrman, E, de Sutter, D, Gevaert, K, Impens, F, Miinalainen, I, van Bockstal, P-J, de Beer, T, Wauben, MHM, Nolte-‘t-Hoen, ENM, Bloch, K, Swinnen, JV, van der Pol, E, Nieuwland, R, Braems, G, Callewaert, N, Mestdagh, P, Vandesompele, J, Denys, H, Eyckerman, S, de Wever, O & Hendrix, A . The generation and use of recombinant extracellular vesicles as biological reference material. Nature communications 2019;10:1: (Amsterdam UMC). 522. Geis JR, Brady A, Wu CC, Spencer J, Ranschaert E, Jaremko JL, Langer SG, Kitts AB, Birch J, Shields WF, van den Hoven van Genderen R, Kotter E, Gichoya JW, Cook TS, Morgan MB, Tang A, Safdar NM, Kohli M. Ethics of artificial intelligence in radiology: summary of the joint European and North American multisociety statement. Insights Imaging 2019; 10:101 (Amsterdam UMC & NKI). 523. Geis JR, Brady AP, Wu CC, Spencer J, Ranshaert E, Jaremko JL, Langer SG, Kitts AB, Birch J, Shields WF, van den Hoven van Genderen R, Kotter E, Gichoya JW, Cook TS, Morgan MB, Tang A, Safdar NM, Kohli M. Ethics of Artificial Intelligence in Radiology: Summary of the Joint European and North American Multisociety Statement. J Am Coll Radiol 2019; 16:1516-21 (Amsterdam UMC & NKI). 524. Geneugelijk, K, Thus, KA, van Deutekom, HWM, Calis, JJA, Borst, E, Keşmir, C, Oudshoorn, M, van der Holt, B, Meijer, E, Zeerleder, S, de Groot, MR, von dem Borne, PA, Schaap, N, Cornelissen, J, Kuball, JR & Spierings, E . Exploratory Study of Predicted Indirectly ReCognizable HLA Epitopes in Mismatched Hematopoietic Cell Transplantations. Frontiers in Immunology 2019;10:: (Amsterdam UMC). 525. Georgescu, C, Corbin, JM, Thibivilliers, S, Webb, ZD, Zhao, YD, Koster, J, Fung, K-M, Asch, AS, Wren, JD & Ruiz-Echevarría, MJ . A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer. BMC cancer 2019;19:1:423 (Amsterdam UMC). 526. Geras KJ, Mann RM, Moy L. Artificial Intelligence for Mammography and Digital Breast Tomosynthesis: Current Concepts and Future Perspectives. Radiology 2019; 293:246-59 (NKI). 527. Geurts-Giele WR, Rosenberg EH, Rens AV, van Leerdam ME, Dinjens WN, Bleeker FE. Somatic mosaicism by a de novo MLH1 mutation as a cause of Lynch syndrome. Mol Genet Genomic Med 2019; 7:e00699 (5 pp) (NKI). 528. Ghadjar P, Fiorino C, Munck Af Rosenschold P, Pinkawa M, Zilli T, van der Heide UA. ESTRO ACROP consensus guideline on the use of image guided radiation therapy for localized prostate cancer. Radiother Oncol 2019; 141:5-13 (NKI). 529. Giardiello D, Steyerberg EW, Hauptmann M, Adank MA, Akdeniz D, Blomqvist C, Bojesen SE, Bolla MK, Brinkhuis M, Chang-Claude J, Czene K, Devilee P, Dunning AM, Easton DF, Eccles DM, Fasching PA, Figueroa J, Flyger H, Garcia-Closas M, Haeberle L, Haiman CA, Hall P, Hamann U, Hopper JL, Jager A, Jakubowska A, Jung A, Keeman R, Kramer I, Lambrechts D, Le Marchand L, Lindblom A, Lubinski J, Manoochehri M, Mariani L, Nevanlinna H, Oldenburg HSA, Pelders S, Pharoah PDP, Shah M, Siesling S, Smit VTHB, Southey MC, Tapper WJ, Tollenaar RAEM, van den Broek AJ, van Deurzen CHM, van Leeuwen FE, van Ongeval C, van 't Veer LJ, Wang Q, Wendt C, Westenend PJ, Hooning MJ, Schmidt MK. Prediction and clinical utility of a contralateral breast cancer risk model. Breast Cancer Res 2019; 21:144 (NKI). 530. Giesbertz NAA, van Harten WH, Bredenoord AL. A duty to recontact in genetics: context matters. Nat Rev Genet 2019; 20:371-2 [Comment] (NKI). 531. Gisler S, Goncalves JP, Akhtar W, de Jong J, Pindyurin AV, Wessels LFA, van Lohuizen M. Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency. Nat Commun 2019; 10:1598 (14 pp) (NKI). 532. Gjonaj L, Sapmaz A, Gonzalez-Prieto R, Vertegaal ACO, Flierman D, Ovaa H. USP7: combining tools towards selectivity. Chem Commun (Camb) 2019; 55:5075-8 (NKI). 533. Goedegebuure, RSA, de Klerk, LK, Bass, AJ, Derks, S & Thijssen, VLJL . Combining Radiotherapy With Anti-angiogenic Therapy and Immunotherapy; A Therapeutic Triad for Cancer?. Frontiers in Immunology 2019;10:: (Amsterdam UMC). 534. Goggins, M, Overbeek, KA, Brand, R, Syngal, S, del Chiaro, M, Bartsch, DK, Bassi, C, Carrato, A, Farrell, J, Fishman, E, Fockens, P, Gress, TM, van Hooft, JE, Hruban, RH, Kastrinos, F, Klein, A, Lennon, AM, Lucas, A, Park, W, Rustgi, A, Simeone, D, Stoffel, E, Vasen, HFA, Cahen, DL, Canto, MI & Bruno, M . Management of patients with increased risk for familial pancreatic cancer: Updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium. Gut 2019 (Amsterdam UMC). 535. Gogola E, Rottenberg S, Jonkers J. Resistance to PARP Inhibitors: lessons from preclinical models of BRCA-associated cancer. Annu Rev Cancer Biol 2019; 3:235-54 (NKI). 536. Gontero P, Marra G, Alessio P, Filippini C, Oderda M, Munoz F, Linares E, Sanchez-Salas R, Challacombe B, Dasgupta P, Goonewardene S, Popert R, Cahill D, Gillatt D, Persad R, Palou J, Joniau S, Piechaud T, Morlacco A, Vidit S, Roupret M, de la Taille A, Albisinni S, Gandaglia G, Mottrie A, Joshi S, Fiscus G, Berger A, Aron M, van der Poel H, Tilki D, Lawrentschuk N, Murphy DG, Leung G, Davis J, Karnes RJ. Salvage radical prostatectomy for recurrent prostate cancer: morbidity and functional outcomes from a large multicenter series of open versus robotic approaches. J Urol 2019; 202:725- 31 (NKI). 537. Gonzalez, ML, Oosterhoff, D, Lindenberg, JJ, Milenova, I, Lougheed, SM, Martianez, T, Dekker, H, Quixabeira, DCA, Hangalapura, B, Joore, J, Piersma, SR, Cervera-Carrascon, V, Santos, JM, Scheper, RJ, Verheul, HMW, Jimenez, CR, Van De Ven, R, Hemminki, A, Van Beusechem, VW & De Gruijl, TD . Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour- mediated immune suppression. OncoImmunology 2019;8:10: (Amsterdam UMC). 538. Gottgens EL, van den Heuvel CN, de Jong MC, Kaanders JH, Leenders WP, Ansems M, Bussink J, Span PN. ACLY (ATP Citrate Lyase) Mediates Radioresistance in Head and Neck Squamous Cell Carcinomas and is a Novel Predictive Radiotherapy Biomarker. Cancers (Basel) 2019; 11:1971 (15 pp) (NKI). 539. Gouw ZAR, La F, van Kranen S, van de Kamer JB, Vogel WV, van Werkhoven E, Sonke JJ, Al-Mamgani A. The Prognostic Value of Baseline 18F-FDG PET/CT in Human Papillomavirus-Positive Versus Human Papillomavirus-Negative Patients With Oropharyngeal Cancer. Clin Nucl Med 2019; 44:e323- e328 (NKI). 540. Govindan, R, Senan, S, Dickgreber, N, Provencio, M, Wu, Y-L, Syrigos, K, Parente, B, Wilson, M, Ziemiecki, R, Chouaki, N, Hossain, A, San Antonio, B, Winfree, K & Vokes, EE . Healthcare resource utilization and associated cost analysis of the PROCLAIM study in patients with stage III non-small- cell lung cancer. Current Medical Research and Opinion 2019;35:10:1761-1767 (Amsterdam UMC). 541. Granzier RWY, van Bastelaar J, van Kuijk SMJ, Hintzen KFH, Heymans C, Theunissen LLB, van Haaren ERM, Janssen A, Beets GL, Vissers YLJ. Reducing seroma formation and its sequelae after mastectomy by closure of the dead space: The interim analysis of a multi-center, double-blind randomized controlled trial (SAM trial). Breast 2019; 46:81-6 (NKI). 542. Gregersen LH, Mitter R, Ugalde AP, Nojima T, Proudfoot NJ, Agami R, Stewart A, Svejstrup JQ. SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell 2019; 177:1797-813 (NKI). 543. Greidanus, MA, Tamminga, SJ, de Rijk, AE, Frings-Dresen, MHW & de Boer, AGEM . What Employer Actions Are Considered Most Important for the Return to Work of Employees with Cancer? A Delphi Study Among Employees and Employers. Journal of occupational rehabilitation 2019;29:2:406-422 (Amsterdam UMC). 544. Griffioen, AW & Nowak-Sliwinska, P . Cell death rocks. Apoptosis 2019;24::205–207. (Amsterdam UMC). 545. Grimme FAB, Seesing MFJ, van Hillegersberg R, van Coevorden F, de Jong KP, Nagtegaal ID, Verhoef C, de Wilt JHW. Liver Resection for Hepatic Metastases from Soft Tissue Sarcoma: A Nationwide Study. Dig Surg 2019; 36:479-86 (NKI). 546. Grivas N, de Bruin D, Barwari K, van Muilenkom E, Tillier C, van Leeuwen PJ, Wit E, Kroese W, van der Poel H. Ultrasensitive prostate-specific antigen level as a predictor of biochemical progression after robot-assisted radical prostatectomy: Towards risk adapted follow-up. J Clin Lab Anal 2019; 33:e22693 (NKI). 547. Grivas N, Kalampokis N, Larcher A, Tyritzis S, Rha KH, Ficarra V, Buffi N, Ploumidis A, Autorino R, Porpiglia F, Mottrie A, De Naeyer G. Robot-assisted versus open partial nephrectomy: comparison of outcomes. A systematic review(NKI). 548. Grivas N, van der Roest RC, de Korne CM, KleinJan GH, Sikorska K, Schoots IG, Tillier C, van der Broek B, Jalink K, Heijmink SWTJ, Buckle T, van Leeuwen FWB, van der Poel HG. The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy. World J Urol 2019; 37:309-15 (NKI). 549. Groen HJM, van der Heijden EHFM, Klinkenberg TJ, Biesma B, Aerts J, Verhagen A, Kloosterziel C, Pieterman R, van den Borne B, Smit HJM, Hoekstra O, Schramel FMNH, van der Noort V, Van Tinteren H, Smit EF, Dingemans AC. Randomised phase 3 study of adjuvant chemotherapy with or without nadroparin in patients with completely resected non-small-cell lung cancer: the NVALT-8 study. Br J Cancer 2019; 121:372-7 (Amsterdam UMC & NKI). 550. Groen, JV, Khawar, AAJ, Bauer, PA, Bonsing, BA, Martini, CH, Mungroop, TH, Vahrmeijer, AL, Vuijk, J, Dahan, A & Mieog, JSD . Meta-analysis of epidural analgesia in patients undergoing pancreatoduodenectomy. BJS Open 2019;3:5:559-571 (Amsterdam UMC). 551. Groen, K, van de Donk, N, Stege, C, Zweegman, S & Nijhof, IS . Carfilzomib for relapsed and refractory multiple myeloma. Cancer management and research 2019;11::2663-2675. (Amsterdam UMC). 552. Groenendijk FH, Treece T, Yoder E, Baron P, Beitsch P, Audeh W, Dinjens WNM, Bernards R, Whitworth P. Estrogen receptor variants in ER-positive basal-type breast cancers responding to therapy like ER-negative breast cancers. NPJ Breast Cancer 2019; 5:15 (8 pp) (NKI). 553. Groenland SL, Mathijssen RHJ, Beijnen JH, Huitema ADR, Steeghs N. Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine. Eur J Clin Pharmacol 2019; 75:1309-18 (NKI). 554. Groenland SL, van Eerden RAG, Verheijen RB, Koolen SLW, Moes DJAR, Desar IME, Reyners AKL, Gelderblom HJ, van Erp NP, Mathijssen RHJ, Huitema ADR, Steeghs N. Therapeutic Drug Monitoring of Oral Anticancer Drugs: The Dutch Pharmacology Oncology Group-Therapeutic Drug Monitoring Protocol for a Prospective Study. Ther Drug Monit 2019; 41:561-7 (NKI). 555. Groenland SL, van Nuland M, Verheijen RB, Schellens JHM, Beijnen JH, Huitema ADR, Steeghs N. Therapeutic Drug Monitoring of Oral Anti-Hormonal Drugs in Oncology. Clin Pharmacokinet 2019; 58:299-308 (NKI). 556. Guchelaar HJ, Sanchez-Spitman A, Dezentje V, Bohringer S, Swen J, Neven P, Gelderblom H. Reply to C.L. Braal et al, H. Brauch et al, and M.P. Goetz et al. J Clin Oncol 2019; 37:1984-5 [Letter] (NKI). 557. Guo, Q, Li, VZ, Nichol, JN, Huang, F, Yang, W, Preston, SEJ, Talat, Z, Lefrère, H, Yu, H, Zhang, G, Basik, M, Gonçalves, C, Zhan, Y, Plourde, D, Su, J, Torres, J, Marques, M, Habyan, SA, Bijian, K, Amant, F, Witcher, M, Behbod, F, McCaffrey, L, Alaoui-Jamali, M, Giannakopoulos, NV, Brackstone, M, Postovit, L-M, del Rincón, SV & Miller, WH . MNK1/Nodal signaling promotes invasive progression of breast ductal carcinoma in situ. Cancer research 2019;79:7:1646-1657 (Amsterdam UMC). 558. Gurney-Champion, OJ, Collins, DJ, Wetscherek, A, Rata, M, Klaassen, R, van Laarhoven, HWM, Harrington, KJ, Oelfke, U & Orton, MR . Principal component analysis for fast and model-free denoising of multi b-value diffusion-weighted MR images. Physics in medicine and biology 2019;64:10: (Amsterdam UMC). 559. Haanappel A, Kroon HM, Schaap DP, Bedrikovetski S, Dudi-Venkata NN, Lee HX, Thomas ML, Liu J, van der Valk MJM, Rutten HJT, Beets GL, Kusters M, Sammour T. Lateral Lymph Node Metastases in Locally Advanced Low Rectal Cancers May Not Be Treated Effectively With Neoadjuvant (Chemo)Radiotherapy Only. Front Oncol 2019; 9:1355 (NKI). 560. Haanen J. Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs. ESMO Open 2019; 4:e000557 [Editorial] (NKI). 561. Haanen JB, Peters S. Characterisation of rare haematological immune-related toxicities. Lancet Haematol 2019; 6:e10-e11 (NKI). 562. Haanstra JF, Dekker EE, Cats A, Nagengast FM, Hardwick JC, Vanhoutvin SA, de Vos Tot Nederveen Cappel WH, Vasen HF, Kleibeuker JH, Koornstra JJ. Effect of chromoendoscopy in the proximal colon on colorectal neoplasia detection in Lynch syndrome: a multicenter randomized controlled trial. Gastrointest Endosc 2019; 90:624-32 (Amsterdam UMC & NKI). 563. Haas RL, van Beek S, Betgen A, Ali S, Schneider CJ, Heres Diddens F, Scholten AN, Koetsveld F, Remeijer P. Substantial volume changes and plan adaptations during preoperative radiotherapy in extremity soft tissue sarcoma patients. Pract Radiat Oncol 2019; 9:115-22 (NKI). 564. Haas RL, van de Sande MAJ. Considering sarcoma staging systems and their implications to personalized care. Chin Clin Oncol 2019; 8(S1):S9 [Editorial] (NKI). 565. Haas RLM, Bonvalot S, Miceli R, Strauss DC, Swallow CJ, Hohenberger P, van Coevorden F. , Rutkowski P, Callegaro D, Hayes AJ, Honore C, Fairweather M, Gladdy R, Jakob J, Szacht M, Fiore M, Chung PW, van Houdt WJ, Raut CP, Gronchi A. Radiotherapy for retroperitoneal liposarcoma: A report from the Transatlantic Retroperitoneal Sarcoma Working Group(NKI). 566. Habets, EJJ, Hendriks, EJ, Taphoorn, MJB, Douw, L, Zwinderman, AH, Vandertop, WP, Barkhof, F, de Witt Hamer, PC & Klein, M . Association between tumor location and neurocognitive functioning using tumor localization maps. Journal of Neuro-Oncology 2019;144:3:573-582 (Amsterdam UMC). 567. Hage JJ. History Off-Hand: Bunnell's No-Man's Land. Hand (N Y) 2019; 14:570-4 (NKI). 568. Hagenbeek A, Mooij H, Zijlstra J, Lugtenburg P, Van Imhoff G, Nijland M, Tonino S, Hutchings M, Spiering M, Liu R, Van Tinteren H, Kersten MJ. Phase I dose-escalation study of brentuximab-vedotin combined with dexamethasone, high-dose cytarabine and cisplatin, as salvage treatment in relapsed/refractory classical Hodgkin lymphoma: The HOVON/LLPC Transplant BRaVE study. Haematologica 2019; 104:e151-e153 [Letter] (Amsterdam UMC & NKI). 569. Hagens ERC, van Berge Henegouwen MI, van Sandick JW, Cuesta MA, van der Peet DL, Heisterkamp J, Nieuwenhuijzen GAP, Rosman C, Scheepers JJG, Sosef MN, van Hillegersberg.R., Lagarde SM, Nilsson M, Rasanen J, Nafteux P, Pattyn P, Holscher AH, Schroder W, Schneider PM, Mariette C, Castoro C, Bonavina L, Rosati R, De Manzoni G, Mattioli S, Garcia JR, Pera M, Griffin M, Wilkerson P, Chaudry MA, Sgromo B, Tucker O, Cheong E, Moorthy K, Walsh TN, Reynolds J, Tachimori Y, Inoue H, Matsubara H, Kosugi SI, Chen H, Law SYK, Pramesh CS, Puntambekar SP, Murthy S, Linden P, Hofstetter WL, Kuppusamy MK, Shen KR, Darling GE, Sabino FD, Grimminger PP, Meijer SL, Bergman JJGH, Hulshof MCCM, van Laarhoven HWM, Mearadji B, Bennink RJ, Annema JT, Dijkgraaf MGW, Gisbertz SS. Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study. BMC Cancer 2019; 19:662 (Amsterdam UMC & NKI). 570. Hakami, A, Zwartkruis, E, Radonic, T & Daniels, JMA . Atypical bronchial carcinoid with postobstructive mycobacterial infection. BMC Pulmonary Medicine 2019;19:1: (Amsterdam UMC). 571. Halaska, MJ, Uzan, C, Han, SN, Fruscio, R, Dahl Steffensen, K, van Calster, B, Stankusova, H, Marchette, MD, Mephon, A, Rouzier, R, Witteveen, PO, Vergani, P, van Calsteren, K, Rob, L & Amant, F . Characteristics of patients with cervical cancer during pregnancy: A multicenter matched cohort study. An initiative from the International Network on Cancer, Infertility and Pregnancy. International journal of gynecological cancer 2019;29:4:676-682 (Amsterdam UMC). 572. Hall WA, Paulson ES, van der Heide UA, Fuller CD, Raaymakers BW, Lagendijk JJW, Li XA, Jaffray DA, Dawson LA, Erickson B, Verheij M, Harrington KJ, Sahgal A, Lee P, Parikh PJ, Bassetti MF, Robinson CG, Minsky BD, Choudhury A, Tersteeg RJHA, Schultz CJ. The transformation of radiation oncology using real-time magnetic resonance guidance: A review. Eur J Cancer 2019; 122:42-52 (Amsterdam UMC & NKI). 573. Ham JC, van Herpen CML, Driessen CML, van der Graaf WTA, Husson O. Health-related quality of life of patients treated with chemoradiotherapy plus or minus prophylactic antibiotics to reduce the number of pneumonias for locally advanced head and neck cancer, the PANTAP study. Oral Oncol 2019; 96:105-12 (NKI). 574. Hammel, P, Kindler, HL, Reni, M, van Cutsem, E, MacArulla, T, Hall, MJ, Park, JO, Hochhauser, D, Arnold, D, Oh, DY, Reinacher-Schick, A, Tortora, G, Algül, H, O. Health-related quality of life in patients with a germline BRCA mutation and metastatic pancreatic cancer receiving maintenance olaparib. Annals of oncology 2019;30:12:1959-1968 (Amsterdam UMC). 575. Hamming-Vrieze O, Depauw N, Craft DL, Chan AW, Rasch CRN, Verheij M, Sonke JJ, Kooy HM. Impact of setup and range uncertainties on TCP and NTCP following VMAT or IMPT of oropharyngeal cancer patients. Phys Med Biol 2019; 64:095001 (10 pp) (Amsterdam UMC & NKI). 576. Hanna-Sawires, RG, Groen, JV, Klok, FA, Tollenaar, RAEM, Mesker, WE, Swijnenburg, RJ, Vahrmeijer, AL, Bonsing, BA & Mieog, JSD . Outcomes following pancreatic surgery using three different thromboprophylaxis regimens. British journal of surgery 2019;106:6:765-773 (Amsterdam UMC). 577. Hardon, SF, van Kasteren, RJ, Dankelman, J, Bonjer, HJ, Tuynman, JB & Horeman, T . The value of force and torque measurements in transanal total mesorectal excision (TaTME). Techniques in Coloproctology 2019;23:9:843-852 (Amsterdam UMC). 578. Hartgerink, D, Swinnen, A, Roberge, D, Nichol, A, Zygmanski, P, Yin, F-F, Deblois, F, Hurkmans, C, Ong, CL, Bruynzeel, A, Aizer, A, Fiveash, J, Kirckpatrick, J, Guckenberger, M, Andratschke, N, de Ruysscher, D, Popple, R & Zindler, J . LINAC based stereotactic radiosurgery for multiple brain metastases: guidance for clinical implementation. Acta Oncologica 2019;58:9:1275-1282 (Amsterdam UMC). 579. Hashimoto N, Nakamichi N, Nanmo H, Kimura KI, Masuo Y, Sakai Y, Schinkel AH, Sato S, Soga T, Kato Y. Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein. Pharm Res 2019; 36:158 (11 pp) (NKI). 580. Hassan, C, East, J, Radaelli, F, Spada, C, Benamouzig, R, Bisschops, R, Bretthauer, M, Dekker, E, Dinis- Ribeiro, M, Ferlitsch, M, Fuccio, L, Awadie, H, Gralnek, I, Jover, R, Kaminski, MF, Pellisé, M, Triantafyllou, K, Vanella, G, Mangas-Sanjuan, C, Frazzoni, L, van Hooft, JE & Dumonceau, J-M . Bowel preparation for colonoscopy: European society of gastrointestinal endoscopy (esge) guideline- update 2019. Endoscopy 2019;51:8:775-794 (Amsterdam UMC). 581. Hassan, C, Wysocki, PT, Fuccio, L, Seufferlein, T, Dinis-Ribeiro, MR, Brandão, C, Regula, J, Frazzoni, L, Pellise, M, Alfieri, S, Dekker, E, Jover, R, Rosati, G, Senore, C, Spada, C, Gralnek, I, Dumonceau, J-M, van Hooft, JE, van Cutsem, E & Ponchon, T . Endoscopic surveillance after surgical or endoscopic resection for colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Digestive Oncology (ESDO) Guideline. Endoscopy 2019;51:3:266-277 (Amsterdam UMC). 582. Hassouni, BEL, Infante, J, Mantini, G, Ricci, C, Funel, N, Giovannetti, E & Peters, GJ . Uridine cytidine kinase 2 as a potential biomarker for treatment with RX-3117 in pancreatic cancer*. Anticancer Research 2019;39:7:3609-3614 (Amsterdam UMC). 583. Haveman, LM, Ranft, A, vd Berg, H, Smets, A, Kruseova, J, Ladenstein, R, Brichard, B, Paulussen, M, Kuehne, T, Juergens, H, Klco-Brosius, S, Dirksen, U & Merks, JHM . The relation of radiological tumor volume response to histological response and outcome in patients with localized Ewing Sarcoma. Cancer medicine 2019;8:3:1086-1094 (Amsterdam UMC). 584. Hazenberg, MD, Haverkate, NJE, van Lier, YF, Spits, H, Krabbendam, L, Bemelman, WA, Buskens, CJ, Blom, B & Shikhagaie, MM . Human ectoenzyme-expressing ILC3: Immunosuppressive innate cells that are depleted in graft-versus-host disease. Blood advances 2019;3:22:3650-3660 (Amsterdam UMC). 585. Heeg E, Civil YA, Hillen MA, Smorenburg CH, Woerdeman LAE, Groen EJ, Winter-Warnars HAO, Peeters MTFD. Impact of Second Opinions in Breast Cancer Diagnostics and Treatment: A Retrospective Analysis. Ann Surg Oncol 2019; 26:4355-63 (Amsterdam UMC & NKI). 586. Heeg E, Harmeling JX, Becherer BE, Marang-van de Mheen PJ, Vrancken Peeters MTFD, Mureau MAM. Nationwide population-based study of the impact of immediate breast reconstruction after mastectomy on the timing of adjuvant chemotherapy. Br J Surg 2019; 106:1640-8 (NKI). 587. Heeg E, Schreuder K, Spronk PER, Oosterwijk JC, Marang-van de Mheen PJ, Siesling S, Peeters MTFD, NABON Breast Cancer Audit. Hospital transfer after a breast cancer diagnosis: A population-based study in the Netherlands of the extent, predictive characteristics and its impact on time to treatment. Eur J Surg Oncol 2019; 45:560-6 (NKI). 588. Heeman, F, Yaqub, M, Lopes Alves, I, Heurling, K, Berkhof, J, Gispert, JD, Bullich, S, Foley, C, Lammertsma, AA & AMYPAD Consortium . Optimized dual-time-window protocols for quantitative [18F]flutemetamol and [18F]florbetaben PET studies. EJNMMI Research 2019;9:1:32 (Amsterdam UMC & NKI). 589. Heemskerk-Gerritsen BAM, Jager A, Koppert LB, Obdeijn AI, Collee M, Meijers-Heijboer HEJ, Jenner DJ, Oldenburg HSA, van Engelen K, de Vries J, van Asperen CJ, Devilee P, Blok MJ, Kets CM, Ausems MGEM, Seynaeve C, Rookus MA, Hooning MJ. Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2019; 177:723-33 (NKI). 590. Heemskerk-Gerritsen, BAM, Jager, A, Koppert, LB, Obdeijn, AI-M, Collée, M, Meijers-Heijboer, HEJ, Jenner, DJ, Oldenburg, HSA, van Engelen, K, de Vries, J, van Asperen, CJ, Devilee, P, Blok, MJ, Kets, CM, Ausems, MGEM, Seynaeve, C, Rookus, MA & Hooning, MJ . Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment 2019;177:3:723-733 (Amsterdam UMC). 591. Heeren, AM, Rotman, J, Stam, AGM, Pocorni, N, Gassama, A, Samuels, S, Bleeker, MCG, Mom, CH, Zijlmans, HJMAA, Kenter, GG, Jordanova, ES & de Gruijl, TD . Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels. Journal for Immunotherapy of Cancer 2019;7:1: (Amsterdam UMC & NKI). 592. Heeren, AM, van Luijk, IF, Lakeman, J, Pocorni, N, Kole, J, de Menezes, RX, Kenter, GG, Bosse, T, de Kroon, CD & Jordanova, ES . Neoadjuvant cisplatin and paclitaxel modulate tumor-infiltrating T cells in patients with cervical cancer. Cancer Immunology and Immunotherapy 2019;68:11:1759-1767 (Amsterdam UMC). 593. Heideman, DAM, Xu, L, Hesselink, AT, Doorn, S, Ejegod, DM, Pedersen, H, Quint, WGV, Bonde, J & Arbyn, M . Clinical performance of the HPV-Risk assay on cervical samples in SurePath medium using the VALGENT-4 panel. Journal of Clinical Virology 2019;121:104201.: (Amsterdam UMC). 594. Heijink AM, Talens F, Jae LT, van Gijn SE, Fehrmann RSN, Brummelkamp TR, van Vugt MATM. BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity. Nat Commun 2019; 10:100 (NKI). 595. Heineman, DJ & van Berge Henegouwen, MI . Extensive thoracoscopic mediastinal lymph node dissection on the left side: How it should be done. Journal of thoracic disease 2019;11:1:62-64 (Amsterdam UMC). 596. Heineman, DJ, Hoeijmakers, F, Beck, N, Dickhoff, C, Daniels, JM, Schreurs, WH & Jakobsen, E . Impact of health care organization on surgical lung cancer care. Lung Cancer 2019;135::181-187. (Amsterdam UMC). 597. Heinhuis KM, Ros W, Kok M, Steeghs N, Beijnen JH, Schellens JHM. Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors. Ann Oncol 2019; 30:219-35 (NKI). 598. Heinrich, S, Besselink, M, Moehler, M, van Laethem, J-L, Ducreux, M, Grimminger, P, Mittler, J, Lang, H, Lutz, MP & Lesurtel, M . Opinions and use of neoadjuvant therapy for resectable, borderline resectable, and locally advanced pancreatic cancer: International survey and case-vignette study. BMC cancer 2019;19:1: (Amsterdam UMC). 599. Helderman, RFCPA, Löke, DR, Kok, HP, Oei, AL, Tanis, PJ, Franken, NAPK & Crezee, J . Variation in clinical application of hyperthermic intraperitoneal chemotherapy. Cancers 2019;11:1: (Amsterdam UMC). 600. Hellingman D, de Wit-van der Veen BJ, Wan OY, van der Ploeg I, Rutgers EJT, Stokkel MPM. Sentinel lymph node nonvisualization after intratumoral radioisotope tracer injection in breast cancer is not associated with a higher nodal metastasis rate or worse outcomes. J Surg Oncol 2019; 119:421-9 (NKI). 601. Hellingman D, Donswijk ML, Winter-Warnars GAO, de Koekkoek-Doll P, Pinas M, Budde-van NY, Westerga J, Vrancken Peeters MTFD, Kimmings N, Stokkel MPM. Feasibility of radioguided occult lesion localization of clip-marked lymph nodes for tailored axillary treatment in breast cancer patients treated with neoadjuvant systemic therapy. EJNMMI Res 2019; 9:94 (NKI). 602. Hellingman D, Wan OY, de Wit-van der Veen BJ, van der Ploeg I, Elkhuizen PHM, Rutgers EJT, Stokkel MPM. Predictive risk factors for sentinel lymph node nonvisualization on planar lymphoscintigraphy using an intratumoral injection in patients with primary breast cancer. Nucl Med Commun 2019; 40:317-24 (NKI). 603. HEMA-ICU Study Group, de Vries, VA, Müller, MCA, Arbous, MS, Biemond, BJ, Blijlevens, NMA, Kusadasi, N, Span, LRF, Vlaar, APJ, van Westerloo, DJ, Kluin-Nelemans, HC & van den Bergh, WM . Long-Term Outcome of Patients With a Hematologic Malignancy and Multiple Organ Failure Admitted at the Intensive Care. Critical care medicine 2019;47:2:e120-e128 (Amsterdam UMC). 604. Hendra, FN, Natsir Kalla, DS, Van Cann, EM, de Vet, HCW, Helder, MN & Forouzanfar, T . Radical vs conservative treatment of intraosseous ameloblastoma. Oral Diseases 2019;25:7:1683-1696 (Amsterdam UMC). 605. Hendricksen K, Aziz A, Bes P, Chun FK, Dobruch J, Kluth LA, Gontero P, Necchi A, Noon AP, van Rhijn BWG, Rink M, Roghmann F, Roupret M, Seiler R, Shariat SF, Qvick B, Babjuk M, Xylinas E. Discrepancy Between European Association of Urology Guidelines and Daily Practice in the Management of Non- muscle-invasive Bladder Cancer: Results of a European Survey. Eur Urol Focus 2019; 5:681-8 (NKI). 606. Hendricksen K. Device-assisted intravesical therapy for non-muscle invasive bladder cancer. Transl Androl Urol 2019; 8:94-100 (NKI). 607. Hendriks MP, Verbeek XAAM, van Vegchel T, van der Sangen MJC, Strobbe LJA, Merkus JWS, Zonderland HM, Smorenburg CH, Jager A, Siesling SS. Transformation of the National Breast Cancer Guideline Into Data-Driven Clinical Decision Trees. JCO Clin Cancer Inform 2019; 3:1-14 (NKI). 608. Hendriks, EJ, Idema, S, Hervey-Jumper, SL, Bernat, AL, Zwinderman, AH, Barkhof, F, Vandertop, WP, Mandonnet, E, Duffau, H, Berger, MS & De Witt Hamer, PC . Preoperative Resectability Estimates of Nonenhancing Glioma by Neurosurgeons and a Resection Probability Map. Neurosurgery 2019;85:2:E304-E313 (Amsterdam UMC). 609. Hendriksma M, van Loon Y, Klop WMC, Hakkesteegt MM, Heijnen BJ, El Hasnaoui I, de Jong M, Langeveld TPM, van Benthem PPG, Baatenburg de Jong RJ, Sjogren EV. Quality of life and voice outcome of patients treated with transoral CO2 laser microsurgery for early glottic carcinoma (T1- T2): a 2-year follow-up study. Eur Arch Otorhinolaryngol 2019; 276:805-14 (NKI). 610. Henn, J, Spier, I, Adam, RS, Holzapfel, S, Uhlhaas, S, Kayser, K, Plotz, G, Peters, S & Aretz, S . Diagnostic yield and clinical utility of a comprehensive gene panel for hereditary tumor syndromes. Hereditary cancer in clinical practice 2019;17:1: (Amsterdam UMC). 611. Henricks LM, Lunenburg CATC, de Man FM, Meulendijks D, Frederix GWJ, Kienhuis E, Creemers GJ, Baars A, Dezentje VO, Imholz ALT, Jeurissen FJF, Portielje JEA, Jansen RLH, Hamberg P, Ten Tije AJ, Droogendijk HJ, Koopman M, Nieboer P, van de Poel MHW, Mandigers CMPW, Rosing H, Beijnen JH, van Werkhoven E, van Kuilenburg ABP, van Schaik RHN, Mathijssen RHJ, Swen JJ, Gelderblom H, Cats A, Guchelaar HJ, Schellens JHM. A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy. Eur J Cancer 2019; 107:60-7 (Amsterdam UMC & NKI). 612. Henricks LM, van Merendonk LN, Meulendijks D, Deenen MJ, Beijnen JH, de Boer A, Cats A, Schellens JHM. Effectiveness and safety of reduced-dose fluoropyrimidine therapy in patients carrying the DPYD*2A variant: a matched pair analysis. Int J Cancer 2019; 144:2347-54 (NKI). 613. Henricks, LM, Lunenburg, CATC, de Man, FM, Meulendijks, D, Frederix, GWJ, Kienhuis, E, Creemers, G-J, Baars, A, Dezentjé, VO, Imholz, ALT, Jeurissen, FJF, Portielje, JEA, Jansen, RLH, Hamberg, P, ten Tije, AJ, Droogendijk, HJ, Koopman, M, Nieboer, P, van de Poel, MHW, Mandigers, CMPW, Rosing, H, Beijnen, JH, van Werkhoven, E, van Kuilenburg, ABP, van Schaik, RHN, Mathijssen, RHJ, Swen, JJ, Gelderblom, H, Cats, A, Guchelaar, H-J & Schellens, JHM . A cost analysis of upfront DPYD genotype– guided dose individualisation in fluoropyrimidine-based anticancer therapy. European journal of cancer (Oxford, England 2019;107::60-67. (Amsterdam UMC). 614. Henselmans, I, Brugel, SD, de Haes, HCJM, Wolvetang, KJA, de Vries, LM, Pieterse, AH, Baas-Thijssen, MCM, de Vos, FYF, van Laarhoven, HWM & Smets, EMA . Promoting shared decision making in advanced cancer. Patient education and counseling 2019;102:5:916-923 (Amsterdam UMC). 615. Henselmans, I, van Laarhoven, HWM, de Haes, HCJM, Tokat, M, Engelhardt, EG, van Maarschalkerweerd, PEA, Kunneman, M, Ottevanger, PB, Dohmen, SE, Creemers, GJ, Sommeijer, DW, de Vos, FYFL & Smets, EMA . Training for Medical Oncologists on Shared Decision-Making About Palliative Chemotherapy. oncologist 2019;24:2:259-265 (Amsterdam UMC). 616. Herbst RS, Baas P, Perez-Gracia JL, Felip E, Kim DW, Han JY, Molina JR, Kim JH, Dubos AC, Ahn MJ, Majem M, Fidler MJ, Surmont V, de Castro G, Garrido M, Shentu Y, Emancipator K, Samkari A, Jensen EH, Lubiniecki GM, Garon EB. Use of archival versus newly collected tumor samples for assessing PD- L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial. Ann Oncol 2019; 30:281-9 (NKI). 617. Hermans BCM, Derks JL, Thunnissen E, van Suylen RJ, den Bakker MA, Groen HJM, Smit EF, Damhuis RA, van den Broek EC, Stallinga CM, Roemen GM, Speel EJM, Dingemans AC. Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC). Lung Cancer 2019; 130:179-86 (Amsterdam UMC & NKI). 618. Hermans TJN, Voskuilen CS, Deelen M, Mertens LS, Horenblas S, Meijer RP, Boormans JL, Aben KK, van der Heijden MS, Pos FJ, de Wit R, Beerepoot LV, Verhoeven RHA, van Rhijn BWG. Superior Efficacy of Neoadjuvant Chemotherapy and Radical Cystectomy in cT3-4aN0M0 compared to cT2N0M0 Bladder Cancer. Int J Cancer 2019; 144:1453-9 (NKI). 619. Hermans, BCM, Derks, JL, Thunnissen, E, van Suylen, RJ, den Bakker, MA, Groen, HJM, Smit, EF, Damhuis, RA, van den Broek, EC, Ruland, A, Speel, EJM, Dingemans, AMC & PALGA-Group . DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile. Lung Cancer 2019;138::102-108. (Amsterdam UMC). 620. Hermans, BCM, Derks, JL, Thunnissen, E, van Suylen, RJ, den Bakker, MA, Groen, HJM, Smit, EF, Damhuis, RA, van den Broek, EC, Stallinga, CM, Roemen, GM, Speel, EJM, Dingemans, AMC & PALGA- Group . Prevalence and prognostic value of PD-L1 expression in molecular subtypes of metastatic large cell neuroendocrine carcinoma (LCNEC). Lung Cancer 2019;130::179-186. (Amsterdam UMC). 621. Heukelom J, Fuller CD. Head and Neck Cancer Adaptive Radiation Therapy (ART): Conceptual Considerations for the Informed Clinician. Semin Radiat Oncol 2019; 29:258-73 (NKI). 622. Heukelom, J, Navran, A, Gouw, ZAR, Tesselaar, ME, Zuur, CL, van Werkhoven, E, Sonke, J-J, Rasch, CRN & Al-Mamgani, A . Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis. Otolaryngology-head and neck surgery 2019;161:2:288-296 (Amsterdam UMC & NKI). 623. Heus, C, Bakker, N, Verduin, WM, Doodeman, HJ & Houdijk, APJ . Impact of Body Composition on Surgical Outcome in Rectal Cancer Patients, a Retrospective Cohort Study. World journal of surgery 2019;43:5:1370–1376 (Amsterdam UMC). 624. Hidding, JT, Beurskens, CHG, de Vries, MT, Nijhuis-van der Sanden, MWG, van Laarhoven, HWM & van der Wees, PJ . Accuracy of a single measurement site for self-monitoring of patients with breast cancer at risk for lymphedema. Physiotherapy Theory and Practice 2019;35:12:1322-1327 (Amsterdam UMC). 625. Hillengass, J, Usmani, S, Rajkumar, SV, Durie, BGM, Mateos, M-V, Lonial, S, Joao, C, Anderson, KC, García-Sanz, R, Serra, ER, du, J, van de Donk, N, Berdeja, JG, Terpos, E, Zamagni, E, Kyle, RA, San Miguel, J, Goldschmidt, H, Giralt, S, Kumar, S, Raje, N, Ludwig, H, Ocio, E, Schots, R, Einsele, H, Schjesvold, F, Chen, W-M, Abildgaard, N, Lipe, BC, Dytfeld, D, Wirk, BM, Drake, M, Cavo, M, Lahuerta, JJ & Lentzsch, S . International myeloma working group consensus recommendations on imaging in monoclonal plasma cell disorders. Lancet Oncology 2019;20:6:e302-e312 (Amsterdam UMC). 626. Hoefsmit EP, Rozeman EA, Haanen JBAG, Blank CU. Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events. ESMO Open 2019; 4:e000472 (NKI). 627. Hoeijmakers F, Heineman DJ, Beck N, Klamer J, Tollenaar RAEM, Wouters MWJM, Schreurs WH. Mediastinoscopy for Staging of Non-Small Cell Lung Cancer: Surgical Performance in The Netherlands. Ann Thorac Surg 2019; 107:1024-31 (Amsterdam UMC & NKI). 628. Hoekstra RJ, Trip EJ, Ten Kate FJ, Horenblas S, Lock MT. Penile intraepithelial neoplasia: Nomenclature, incidence and progression to malignancy in the Netherlands. Int J Urol 2019; 26:353- 7 (NKI). 629. Hof, SVT, Delaney, AR, Tekatli, H, Twisk, J, Slotman, BJ, Senan, S, Dahele, M & Verbakel, WF . Knowledge-Based Planning for Identifying High-Risk Stereotactic Ablative Radiation Therapy Treatment Plans for Lung Tumors Larger Than 5 cm. International Journal of Radiation Oncology Biology Physics 2019;103:1:259-267 (Amsterdam UMC). 630. Hofer, TP, van de Loosdrecht, AA, Stahl-Hennig, C, Cassatella, MA & Ziegler-Heitbrock, L . 6-Sulfo LacNAc (Slan) as a Marker for Non-classical Monocytes. Frontiers in Immunology 2019;10:2052: (Amsterdam UMC). 631. Hofland, T, de Weerdt, I, ter Burg, H, de Boer, R, Tannheimer, S, Tonino, SH, Kater, AP & Eldering, E . Dissection of the Effects of JAK and BTK Inhibitors on the Functionality of Healthy and Malignant Lymphocytes. Journal of immunology (Baltimore, Md. 2019;203:8:2100-2109 (Amsterdam UMC). 632. Hofland, T, Eldering, E, Kater, AP & Tonino, SH . Engaging Cytotoxic T and NK Cells for Immunotherapy in Chronic Lymphocytic Leukemia. International journal of molecular sciences 2019;20:17: (Amsterdam UMC). 633. Hofland, T, Endstra, S, Gomes, CKP, de Boer, R, de Weerdt, I, Bobkov, V, Riedl, JA, Heukers, R, Smit, MJ, Eldering, E, Levin, M-D, Kater, AP & Tonino, SH . Natural Killer Cell Hypo-responsiveness in Chronic Lymphocytic Leukemia can be Circumvented In Vitro by Adequate Activating Signaling. HemaSphere 2019;3:6:e308 (Amsterdam UMC). 634. Hogan SA, Courtier A, Cheng PF, Jaberg-Bentele NF, Goldinger SM, Manuel M, Perez S, Plantier N, Mouret JF, Nguyen-Kim TDL, Raaijmakers MM, Kvistborg P, Pasqual N, Haanen JBAG, Dummer R, Levesque MP. Peripheral blood TCR repertoire profiling may facilitate patient stratification for immunotherapy against melanoma. Cancer Immunol Res 2019; 7:77-85 (NKI). 635. Hohenberger P, Bonvalot S, van Coevorden F, Rutkowski P, Stoeckle E, Olungu C, Litiere S, Wardelmann E, Gronchi A, Casali P. Quality of surgery and surgical reporting for patients with primary gastrointestinal stromal tumours participating in the EORTC STBSG 62024 adjuvant imatinib study. Eur J Cancer 2019; 120:47-53 (NKI). 636. Hol JA, Lopez-Yurda MI, Van Tinteren H, van Grotel M, Godzinski J, Vujanic G, Oldenburger F, de Camargo B, Ramirez-Villar GL, Bergeron C, Pritchard-Jones K, Graf N, van den Heuvel-Eibrink MM. Prognostic significance of age in 5631 patients with Wilms tumour prospectively registered in International Society of Paediatric Oncology (SIOP) 93-01 and 2001. PLoS One 2019; 14:e0221373 (NKI). 637. Hol, JC, van Oostendorp, SE, Tuynman, JB & Sietses, C . Long-term oncological results after transanal total mesorectal excision for rectal carcinoma. Techniques in Coloproctology 2019;23:9:903-911 (Amsterdam UMC). 638. Holleman MS, Van Tinteren H, Groen HJ, Al MJ, Uyl-de Groot CA. First-line tyrosine kinase inhibitors in EGFR mutation-positive non-small-cell lung cancer: a network meta-analysis. Onco Targets Ther 2019; 12:1413-21 (NKI). 639. Holmqvist, AS, Chen, Y, Berano Teh, J, Sun, C, Birch, JM, van den Bos, C, Diller, LR, Dilley, K, Ginsberg, J, Martin, LT, Nagarajan, R, Nathan, PC, Neglia, JP, Terenziani, M, Tishler, D, Meadows, AT, Robison, LL, Oberlin, O & Bhatia, S . Risk of solid subsequent malignant neoplasms after childhood Hodgkin lymphoma–identification of high-risk populations to guide surveillance: A report from the Late Effects Study Group. Cancer 2019;125:8:1373-1383 (Amsterdam UMC). 640. Holtmaat, K, van der Spek, N, Lissenberg-Witte, BI, Cuijpers, P & Verdonck-de Leeuw, IM . Positive mental health among cancer survivors. Supportive Care in Cancer 2019;27:2:443-450 (Amsterdam UMC). 641. Höppener, DJ, Nierop, PMH, van Amerongen, MJ, Olthof, PB, Galjart, B, van Gulik, TM, de Wilt, JHW, Grünhagen, DJ, Rahbari, NN & Verhoef, C . The Disease-Free Interval Between Resection of Primary Colorectal Malignancy and the Detection of Hepatic Metastases Predicts Disease Recurrence But Not Overall Survival. Annals of surgical oncology 2019;26:9:2812-2820 (Amsterdam UMC). 642. Horn T, Kronke M, Rauscher I, Haller B, Robu S, Wester HJ, Schottelius M, van Leeuwen FWB, van der Poel HG, Heck M, Gschwend JE, Weber W, Eiber M, Maurer T. Single Lesion on Prostate-specific Membrane Antigen-ligand Positron Emission Tomography and Low Prostate-specific Antigen Are Prognostic Factors for a Favorable Biochemical Response to Prostate-specific Membrane Antigen- targeted Radioguided Surgery in Recurrent Prostate Cancer. Eur Urol 2019; 76:517-23 (NKI). 643. Horn V, Uckelmann M, Zhang H, Eerland J, Aarsman I, le Paige UB, Davidovich C, Sixma TK, van Ingen H. Structural basis of specific H2A K13/K15 ubiquitination by RNF168. Nat Commun 2019; 10:1751 (NKI). 644. Horrevorts, SK, Stolk, DA, van de Ven, R, Hulst, M, van Het Hof, B, Duinkerken, S, Heineke, MH, Ma, W, Dusoswa, SA, Nieuwland, R, Garcia-Vallejo, JJ, van de Loosdrecht, AA, de Gruijl, TD, van Vliet, SJ & van Kooyk, Y . Glycan-modified melanoma-derived apoptotic extracellular vesicles as antigen source for anti-tumor vaccination. Cancers 2019;11:9: (Amsterdam UMC). 645. Horwich, A, Babjuk, M, Bellmunt, J, Bruins, HM, Reijke, TMD, Santis, MD, Gillessen, S, James, N, Maclennan, S, Palou, J, Powles, T, Ribal, MJ, Shariat, SF, Kwast, TVD, Xylinas, E, Agarwal, N, Arends, T, Bamias, A, Birtle, A, Black, PC, Bochner, BH, Bolla, M, Boormans, JL, Bossi, A, Briganti, A, Brummelhuis, I, Burger, M, Castellano, D, Cathomas, R, Chiti, A, Choudhury, A, Compérat, E, Crabb, S, Culine, S, Bari, BD, Blok, WD, de Visschere, PJL, Decaestecker, K, Dimitropoulos, K, Dominguez-Escrig, JL, Fanti, S, Fonteyne, V, Frydenberg, M, Futterer, JJ, Gakis, G, Geavlete, B, Gontero, P, Grubmüller, B, Hafeez, S, Hansel, DE, Hartmann, A, Hayne, D, Henry, AM, Hernandez, V, Herr, H, Herrmann, K, Hoskin, P, Huguet, J, Jereczek-Fossa, BA, Jones, R, Kamat, AM, Khoo, V, Kiltie, AE, Krege, S, Ladoire, S, Lara, PC, Leliveld, A, Linares-Espinós, E, Løgager, V, Lorch, A, Loriot, Y, Meijer, R, Mir, MC, Moschini, M, Mostafid, H, Müller, AC, Müller, CR, N. EAU-ESMO consensus statements on the management of advanced and variant bladder cancer-an international collaborative multi-stakeholder effort: under the auspices of the EAU and ESMO Guidelines Committees†. Annals of oncology 2019;30:11:1697- 1727 (Amsterdam UMC). 646. Hoşal, Ş, Golusiński, W, Andry, G, Leemans, CR & LeFebvre, JL . Fifteen-year history of the European head and neck society. Oral Oncology 2019;97::112-114. (Amsterdam UMC). 647. Hoveling LA, van Maaren MC, Hueting T, Strobbe LJA, Hendriks MP, Sonke GS, Siesling S. Validation of the online prediction model CancerMath in the Dutch breast cancer population. Breast Cancer Res Treat 2019; 178:665-81 (NKI). 648. HOVON CLL study group, Kater, AP, van Oers, MHJ, van Norden, Y, van der Straten, L, Driessen, J, Posthuma, WFM, Schipperus, M, Chamuleau, MED, Nijland, M, Doorduijn, JK, van Gelder, M, Hoogendoorn, M, de Croon, F, Wittebol, S, Kerst, JM, Marijt, EWA, Raymakers, RAP, Schaafsma, MR, Dobber, JA, Kersting, S & Levin, M-D . Feasibility and efficacy of addition of individualized-dose lenalidomide to chlorambucil and rituximab as first-line treatment in elderly and FCR-unfit patients with advanced chronic lymphocytic leukemia. Haematologica 2019;104:1:147-154 (Amsterdam UMC). 649. Huang L, Jansen L, Balavarca Y, Molina-Montes E, Babaei M, van der Geest L, Lemmens V, van Eycken L, De Schutter H, Johannesen TB, Fristrup CW, Mortensen MB, Primic-Zakelj M, Zadnik V, Becker N, Hackert T, Magi M, Cassetti T, Sassatelli R, Grutzmann R, Merkel S, Goncalves AF, Bento MJ, Hegyi P, Lakatos G, Szentesi A, Moreau M, van de Velde T, Broeks A, Sant M, Minicozzi P, Mazzaferro V, Real FX, Carrato A, Molero X, Besselink MG, Malats N, Buchler MW, Schrotz-King P, Brenner H. Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations. Gut 2019; 68:130-9 (Amsterdam UMC & NKI). 650. Huang, L, Balavarca, Y, van der Geest, L, Lemmens, V, van Eycken, L, de Schutter, H, Johannesen, TB, Zadnik, V, Primic-Žakelj, M, Mägi, M, Grützmann, R, Besselink, MG, Schrotz-King, P, Brenner, H & Jansen, L . Development and validation of a prognostic model to predict the prognosis of patients who underwent chemotherapy and resection of pancreatic adenocarcinoma: A large international population-based cohort study. BMC medicine 2019;17:1: (Amsterdam UMC). 651. Hughes, TP, Mauro, MJ, Cortes, JE, Minami, H, Rea, D, DeAngelo, DJ, Breccia, M, Goh, Y-T, Talpaz, M, Hochhaus, A, Coutre, PL, Ottmann, O, Heinrich, MC, Steegmann, JL, Deininger, MWN, Janssen, JJWM, Mahon, F-X, Minami, Y, Yeung, D, Ross, DM, Tallman, MS, Park, JH, Druker, BJ, Hynds, D, Duan, Y, Meille, C, Hourcade-Potelleret, F, Vanasse, KG, Lang, F & Kim, D-W . Asciminib in chronic myeloid leukemia after Abl kinase inhibitor failure. New England Journal of Medicine 2019;381:24:2315-2326 (Amsterdam UMC). 652. Hui, D, Paiva, CE, del Fabbro, EG, Steer, C, Naberhuis, J, van de Wetering, M, Fernández-Ortega, P, Morita, T, Suh, S-Y, Bruera, E & Mori, M . Prognostication in advanced cancer: update and directions for future research. Supportive care in cancer 2019;27:6:1973-1984 (Amsterdam UMC). 653. Huijbers, EJM, Van Der Werf, IM, Faber, LD, Sialino, LD, Van Der Laan, P, Holland, HA, Cimpean, AM, Thijssen, VLJL, Van Beijnum, JR & Griffioen, AW . Targeting tumor vascular CD99 inhibits tumor growth. Frontiers in Immunology 2019;10:: (Amsterdam UMC). 654. Huijskens, SC, van Dijk, IWEM, Visser, J, Balgobind, BV, Rasch, CRN, Alderliesten, T & Bel, A . The effectiveness of 4DCT in children and adults: A pooled analysis. Journal of applied clinical medical physics / American College of Medical Physics 2019;20:1:276-283 (Amsterdam UMC). 655. Huijts CM, Lougheed SM, Bodalal Z, van Herpen CM, Hamberg P, Tascilar M, Haanen JB, Verheul HM, de Gruijl TD, van der Vliet HJ. The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial. Cancer Immunol Immunother 2019; 68:319-29 (Amsterdam UMC & NKI). 656. Huijts CM, Werter IM, Lougheed SM, Goedegebuure RS, van Herpen CM, Hamberg P, Tascilar M, Haanen JB, Verheul HM, de Gruijl TD, van der Vliet HJ, Dutch WIN-O Consortium. Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma. Cancer Immunol Immunother 2019; 68:319-29 (Amsterdam UMC & NKI). 657. Huijts DD, Guicherit OR, Dekker JWT, van Groningen JT, van Bodegom-Vos L, Bastiaannet E, Govaert JA, Wouters MW, Marang-van de Mheen PJ. Do Outcomes in Elective Colon and Rectal Cancer Surgery Differ by Weekday? An Observational Study Using Data From the Dutch ColoRectal Audit. J Natl Compr Canc Netw 2019; 17:821-8 (NKI). 658. Huis In 't Veld EA, van Coevorden F, Grunhagen DJ, Smith MJ, van Akkooi ACJ, Wouters MWJM, Hayes AJ, Verhoef C, Strauss DC, van Houdt WJ . Outcome after surgical treatment of dermatofibrosarcoma protuberans (DFSP): Is clinical follow-up always indicated? Cancer 2019; 125:735-41 . (NKI). 659. Huis In 't Veld EA, van Houdt WJ. Reply to Follow-up after treatment of dermatofibrosarcoma protuberans. Cancer 2019; 125:3467-9 [Letter] (NKI). 660. Huiskens, J, Bolhuis, K, Engelbrecht, MRW, de Jong, KP, Kazemier, G, Liem, MSL, Verhoef, C, de Wilt, JHW, Punt, CJA, van Gulik, TM, van Amerongen, MJ, Dejong, CHC, Gerhards, MF, Grunhagen, D, Heijmen, L, Hermans, JJ, Keijser, A, Klaase, JM, van Lienden, KP, Molenaar, QI, Patijn, GA, Rijken, AM, Ruers, TM, Swijnenburg, R-J, van Tinteren, H & Dutch Colorectal Cancer Group . Outcomes of Resectability Assessment of the Dutch Colorectal Cancer Group Liver Metastases Expert Panel. Journal of the American College of Surgeons 2019;229:6:523-532 (Amsterdam UMC). 661. Huiskens, J, Kool, BRJ, Bakker, J-M, Bruns, ERJ, de Jonge, SW, Olthof, PB, van Rosmalen, BV, van Gulik, TM, Hooft, L & Punt, CJA . From registration to publication: A study on Dutch academic randomized controlled trials. Research synthesis methods 2019 (Amsterdam UMC). 662. Huiskens, J, Schadde, E, Lang, H, Malago, M, Petrowsky, H, de Santibañes, E, Oldhafer, K, van Gulik, TM & Olthof, PB . Avoiding postoperative mortality after ALPPS–development of a tumor-specific risk score for colorectal liver metastases. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:7:898-905 (Amsterdam UMC). 663. Huizing DMV, Koopman D, van Dalen JA, Gotthardt M, Boellaard R, Sera T, Sinaasappel M, Stokkel MPM, de Wit-van der Veen BJ. Multicentre quantitative (68)Ga PET/CT performance harmonisation. EJNMMI Phys 2019; 6:19 (NKI). 664. Hummel SB, van Lankveld JJ, Oldenburg HSA, Hahn DEE, Kieffer JM, Gerritsma MA, Kuenen MA, Bijker N, Borgstein PJ, Heuff G, Lopes Cardozo AM, Plaisier PW, Rijna H, van der Meij S, van Dulken EJ, Vrouenraets BC, Broomans E, Aaronson NK. Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy. J Sex Marital Ther 2019; 45:91-102 (NKI). 665. Hummel, SB, van Lankveld, JJDM, Oldenburg, HSA, Hahn, DEE, Kieffer, JM, Gerritsma, MA, Kuenen, MA, Bijker, N, Borgstein, PJ, Heuff, G, Lopes Cardozo, AMF, Plaisier, PW, Rijna, H, van der Meij, S, van Dulken, EJ, Vrouenraets, BC, Broomans, E & Aaronson, NK . Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy. Journal of sex & marital therapy 2019;45:2:91-102 (Amsterdam UMC). 666. Hummelink K, Muller M, Linders TC, van der Noort V, Nederlof PM, Baas P, Burgers S, Smit EF, Meijer GA, van den Heuvel MM, van den Broek D, Monkhorst K. Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions. ERJ Open Res 2019; 5:00016-2019 (6 pp) (NKI). 667. IJsbrandy C, Hermens RPMG, Boerboom LWM, Gerritsen WR, van Harten WH, Ottevanger PB. Implementing physical activity programs for patients with cancer in current practice: patients' experienced barriers and facilitators. J Cancer Surviv 2019; 13:703-12 (NKI). 668. Ijselstein, M, Brouwer, T, Abdulrahman, Z, Reidy, E, Ramalheiro, A, Heeren, AM, Vahrmeijer, A, Jordanova, ES & de Miranda, N . Cancer immunophenotyping by 7 colour multispectral imaging without tyramide signal amplification. The Journal of Pathology: Clinical Research 2019;5:1:44138 (Amsterdam UMC). 669. IJspeert H, van Schouwenburg PA, Pico-Knijnenburg I, Loeffen J, Brugieres L, Driessen GJ, Blattmann C, Suerink M, Januszkiewicz-Lewandowska D, Azizi AA, Seidel MG, Jacobs H, van der Burg M. Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans. Front Immunol 2019; 10:1913 (NKI). 670. Ijsselsteijn, ME, Brouwer, TP, Abdulrahman, Z, Reidy, E, Ramalheiro, A, Heeren, AM, Vahrmeijer, A, Jordanova, ES & de Miranda, NF . Cancer immunophenotyping by seven-colour multispectral imaging without tyramide signal amplification. The Journal of Pathology: Clinical Research 2019;5:1:44138 (Amsterdam UMC). 671. International CAncer of the Pancreas Screening (CAPS) Consortium, Konings, ICAW, Canto, MI, Almario, JA, Harinck, F, Saxena, P, Lucas, AL, Kastrinos, F, Whitcomb, DC, Brand, RE, Lachter, J, Malleo, G, Paiella, S, Syngal, S, Saltzman, JR, Stoffel, EM, van Hooft, JE, Hruban, RH, Poley, JW, Fockens, P, Goggins, MG & Bruno, MJ . Surveillance for pancreatic cancer in high-risk individuals. BJS Open 2019;3:5:656-665 (Amsterdam UMC). 672. International Guideline Harmonization Group ototoxicity group, Clemens, E, van den Heuvel-Eibrink, MM, Mulder, RL, Kremer, LCM, Hudson, MM, Skinner, R, Constine, LS, Bass, JK, Kuehni, CE, Langer, T, van Dalen, EC, Bardi, E, Bonne, N-X, Brock, PR, Brooks, B, Carleton, B, Caron, E, Chang, KW, Johnston, K, Knight, K, Nathan, PC, Orgel, E, Prasad, PK, Rottenberg, J, Scheinemann, K, de Vries, ACH, Walwyn, T, Weiss, A, am Zehnhoff-Dinnesen, A, Cohn, RJ & Landier, W . Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium. lancet oncology 2019;20:1:e29-e41 (Amsterdam UMC). 673. International Network on Cancer, Infertility and Pregnancy, Maggen, C, Dierickx, D, Lugtenburg, P, Laenen, A, Cardonick, E, Smakov, R, Bellido, M, Cabrera-Garcia, A, Gziri, MM, Halaska, MJ, Ottevanger, PB, van Calsteren, K, O. Obstetric and maternal outcomes in patients diagnosed with Hodgkin lymphoma during pregnancy: a multicentre, retrospective, cohort study. Lancet. Haematology 2019;6:11:e551-e561 (Amsterdam UMC). 674. International Working Group for Classification of Oesophagitis, Bergman, JJGHM, de Groof, AJ, Pech, O, Ragunath, K, Armstrong, D, Mostafavi, N, Lundell, L, Dent, J, Vieth, M, Tytgat, GN & Sharma, P . An Interactive Web-Based Educational Tool Improves Detection and Delineation of Barrett's Esophagus– Related Neoplasia. Gastroenterology 2019;156:5:1299-1308 (Amsterdam UMC). 675. Irtan S, Van Tinteren H, Graf N, van den Heuvel-Eibrink MM, Heij H, Bergeron C, de Camargo B, Acha T, Spreafico F, Vujanic G, Powis M, Okoye B, Wilde J, Godzinski J, Pritchard-Jones K. Evaluation of needle biopsy as a potential risk factor for local recurrence of Wilms tumour in the SIOP WT 2001 trial. Eur J Cancer 2019; 116:13-20 (NKI). 676. Ivashchenko O, Pouw B, de Witt JK, Koudounarakis E, Nijkamp J, van Veen RLP, Ruers TJM, Karakullukcu BM. Intraoperative verification of resection margins of maxillary malignancies by cone- beam computed tomography. Br J Oral Maxillofac Surg 2019; 57:174-81 (NKI). 677. Jackstadt, R, van Hooff, SR, Leach, JD, Cortes-Lavaud, X, Lohuis, JO, Ridgway, RA, Wouters, VM, Roper, J, Kendall, TJ, Roxburgh, CS, Horgan, PG, Nixon, C, Nourse, C, Gunzer, M, Clark, W, Hedley, A, Yilmaz, OH, Rashid, M, Bailey, P, Biankin, AV, Campbell, AD, Adams, DJ, Barry, ST, Steele, CW, Medema, JP & Sansom, OJ . Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis. Cancer cell 2019;36:3:319-336 (Amsterdam UMC). 678. Jacobs BAW, Deenen MJ, Joerger M, Rosing H, de Vries N, Meulendijks D, Cats A, Beijnen JH, Schellens JHM, Huitema ADR. Pharmacokinetics of capecitabine and four metabolites in a heterogeneous population of cancer patients: a comprehensive analysis. CPT Pharmacometrics Syst Pharmacol 2019; 8:940-50 (NKI). 679. Jacobs W, Schagen SB, Thijssen M, Das E. Preventing adverse information effects on health outcomes: A self-affirmation intervention reduced information-induced cognitive decline in gastrointestinal cancer patients. Soc Sci Med 2019; 226:47-55 (NKI). 680. Jacobse JN, Duane FK, Boekel NB, Schaapveld M, Hauptmann M, Hooning MJ, Seynaeve CM, Baaijens MHA, Gietema JA, Darby SC, van Leeuwen FE, Aleman BMP, Taylor CW. Radiation Dose-Response For Risk Of Myocardial Infarction In Breast Cancer Survivors. Int J Radiat Oncol Biol Phys 2019; 103:595- 604 (NKI). 681. Jansen H, van Oort I, van Andel G, Wijsman BP, Pos FJ, Hulshof MCCM, Hulsbergen-van de Kaa CA, van Leenders GJLH, Futterer JJ, Somford DM, Busstra MB, van Moorselaar RJA, Kiemeney LA, Aben KKH. Immediate treatment vs. active-surveillance in very-low-risk prostate cancer: the role of patient-, tumour-, and hospital-related factors(NKI). 682. Jansen YJL, Rozeman EA, Mason R, Goldinger SM, Geukes Foppen MH, Hoejbergs L, Schmidt H, van Thienen JV, Haanen JBAG, Tiainen L, Svane IM, Makela S, Seremet T, Arance A, Dummer R, Bastholt L, Nyakas M, Straume O, Menzies AM, Long GV, Atkinson V, Blank CU, Neyns B. Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma. Ann Oncol 2019; 30:1154-61 (NKI). 683. Jansen YJL, Verset G, Schats K, Van Dam PJ, Seremet T, Kockx M, Van Laethem JB, Neyns B. Phase I clinical trial of decitabine (5-aza-2'-deoxycytidine) administered by hepatic arterial infusion in patients with unresectable liver-predominant metastases. ESMO Open 2019; 4:e000464 (NKI). 684. Jansen, BHE, Kramer, GM, Cysouw, MCF, Yaqub, MM, de Keizer, B, Lavalaye, J, Booij, J, Vargas, HA, Morris, MJ, Vis, AN, van Moorselaar, RJA, Hoekstra, OS, Boellaard, R & Oprea-Lager, DE . Healthy Tissue Uptake of 68Ga-Prostate-Specific Membrane Antigen, 18F-DCFPyL, 18F-Fluoromethylcholine, and 18F-Dihydrotestosterone. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2019;60:8:1111-1117 (Amsterdam UMC). 685. Jansen, BHE, Nieuwenhuijzen, JA, Oprea-Lager, DE, Yska, MJ, Lont, AP, van Moorselaar, RJA & Vis, AN . Adding multiparametric MRI to the MSKCC and Partin nomograms for primary prostate cancer. Urologic Oncology 2019;37:3:181 (Amsterdam UMC). 686. Jansen, BHE, Yaqub, M, Cysouw, MCF, Vis, AN, van Moorselaar, RJA, Hendrikse, NH, Hoekstra, OS, Boellaard, R & Oprea-Lager, DE . Quantification of 18F-DCFPYL uptake. Journal of Nuclear Medicine 2019 (Amsterdam UMC). 687. Jansen, BHE, Yaqub, M, Voortman, J, Cysouw, MCF, Windhorst, AD, Schuit, RC, Kramer, GM, van den Eertwegh, AJM, Schwarte, LA, Hendrikse, NH, Vis, AN, van Moorselaar, RJA, Hoekstra, OS, Boellaard, R & Oprea-Lager, DE . Simplified methods for quantification of 18F-DCFPYL uptake in patients with prostate cancer. Journal of Nuclear Medicine 2019 (Amsterdam UMC). 688. Jansen, F, Lissenberg-Witte, BI, Krebber, AMH, Cuijpers, P, de Bree, R, Becker-Commissaris, A, Smit, EF, van Straten, A, Eeckhout, GM, Beekman, ATF, Leemans, CR & Verdonck-de Leeuw, IM . Stepped care targeting psychological distress in head and neck cancer and lung cancer patients: which groups specifically benefit? Secondary analyses of a randomized controlled trial. Supportive Care in Cancer 2019;27:12:4543-4553 (Amsterdam UMC). 689. Jansen, H, van Oort, IM, van Andel, G, Wijsman, BP, Pos, FJ, Hulshof, MCCM, Hulsbergen-van de Kaa, CA, van Leenders, GJLH, Fütterer, JJ, Somford, DM, Busstra, MB, van Moorselaar, RJA, Kiemeney, LA & Aben, KKH . Immediate treatment vs. active-surveillance in very-low-risk prostate cancer: the role of patient-, tumour-, and hospital-related factors. Prostate Cancer and Prostatic Diseases 2019;22:4:337-343 (Amsterdam UMC). 690. Jansen, I, Lucas, M, Savci-Heijink, CD, Meijer, SL, Liem, EIML, de Boer, OJ, van Leeuwen, TG, Marquering, HA & de Bruin, DM . Three-dimensional histopathological reconstruction of bladder tumours. Diagnostic pathology 2019;14:1: (Amsterdam UMC). 691. Janssen JM, de Vries N, Venekamp N, Rosing H, Huitema ADR, Beijnen JH. Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma. J Pharm Biomed Anal 2019; 174:561-6 (NKI). 692. Janssen NNY, van Seijen M, Loo CE, Vrancken Peeters MTFD, Hankel T, Sonke JJ, Nijkamp J. Feasibility of Micro-Computed Tomography Imaging for Direct Assessment of Surgical Resection Margins During Breast-Conserving Surgery. J Surg Res 2019; 241:160-9 (NKI). 693. Janssen TM, Kusters M, Wang Y, Wortel G, Monshouwer R, Damen E, Petit SF. Independent knowledge-based treatment planning QA to audit Pinnacle autoplanning. Radiother Oncol 2019; 133:198-204 (NKI). 694. Janssen, QP, Buettner, S, Suker, M, Beumer, BR, Addeo, P, Bachellier, P, Bahary, N, Bekaii-Saab, T, Bali, MA, Besselink, MG, Boone, BA, Chau, I, Clarke, S, Dillhoff, M, El-Rayes, BF, Frakes, JM, Grose, D, Hosein, PJ, Jamieson, NB, Javed, AA, Khan, K, Kim, K-P, Kim, SC, Kim, SS, Ko, AH, Lacy, J, Margonis, GA, McCarter, MD, McKay, CJ, Mellon, EA, Moorcraft, SY, Okada, K-I, Paniccia, A, Parikh, PJ, Peters, NA, Rabl, H, Samra, J, Tinchon, C, van Tienhoven, G, van Veldhuisen, E, Wang-Gillam, A, Weiss, MJ, Wilmink, JW, Yamaue, H, Homs, MYV, van Eijck, CHJ, Katz, MHG & Groot Koerkamp, B . Neoadjuvant FOLFIRINOX in Patients With Borderline Resectable Pancreatic Cancer. Journal of the National Cancer Institute 2019;111:8:782-794 (Amsterdam UMC). 695. Jaramillo, AC, Cloos, J, Lemos, C, Stam, RW, Kaspers, GJL, Jansen, G & Peters, GJ . Ex vivo resistance in childhood acute lymphoblastic leukemia. Leukemia Research 2019;79::45-51 (Amsterdam UMC). 696. Jaspers, J, Mèndez Romero, A, Hoogeman, MS, van den Bent, M, Wiggenraad, RGJ, Taphoorn, MJB, Eekers, DBP, Lagerwaard, FJ, Lucas Calduch, AM, Baumert, BG & Klein, M . Evaluation of the Hippocampal Normal Tissue Complication Model in a Prospective Cohort of Low Grade Glioma Patients-An Analysis Within the EORTC 22033 Clinical Trial. Frontiers in Oncology 2019;9::991 (Amsterdam UMC). 697. Jauw, Y, o. 89 Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo. Journal of Nuclear Medicine 2019;60:12:1825-1832 (Amsterdam UMC). 698. Jauw, YWS, Bensch, F, Brouwers, AH, Hoekstra, OS, Zijlstra, JM, Pieplenbosch, S, Schröder, CP, Zweegman, S, van Dongen, GAMS, Menke-van der Houven van Oordt, CW, de Vries, EGE, de Vet, HCW, Boellaard, R & Huisman, MC . Interobserver reproducibility of tumor uptake quantification with 89Zr-immuno-PET: a multicenter analysis. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:9:1840-1849 (Amsterdam UMC). 699. Jeene PM, Geijsen ED, Muijs CT, Rozema T, Aleman BMP, Muller K, Baas JM, Nuyttens JJ, Wouterse S, Braam PM, Oppedijk V, Ceha HM, Cnossen J, Spruit P, Bongers EM, Berbee M, Mook S, Hulshof MCCM. Small Cell Carcinoma of the Esophagus: A Nationwide Analysis of Treatment and Outcome at Patient Level in Locoregional Disease. Am J Clin Oncol 2019; 42:534-8 (Amsterdam UMC & NKI). 700. Jelvehgaran P, de Bruin DM, Khmelinskii A, Borst G, Steinberg JD, Song JY, de Vos J, van Leeuwen TG, Alderliesten T, de Boer JF, van Herk M. Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: a validation study. J Biophotonics 2019; 12:e201800 [Letter] (NKI). 701. Jelvehgaran P, Steinberg JD, Khmelinskii A, Borst G, Song JY, de Wit N, de Bruin DM, van Herk M. Evaluation of acute esophageal radiation-induced damage using magnetic resonance imaging: a feasibility study in mice. Radiat Oncol 2019; 14:188 (Amsterdam UMC & NKI). 702. Jensen KH, Persson G, Storgaard L, Nielsen BB, Pedersen BW, Maroun LL, Huitema A, Pohl M. Antineoplastic treatment with crizotinib during pregnancy: a case report. Acta Oncol 2019; 58:121-2 [Letter] (NKI). 703. Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeboller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnstrom H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldes T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon- Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collee JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, DeFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, Dork T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, Garcia-Saenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guenel P, Hakansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, Hogdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kuhl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubinski J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML. Shared heritability and functional enrichment across six solid cancers. Nat Commun 2019; 10:431 (NKI). 704. Jin, P, Machiels, M, Crama, KF, Visser, J, van Wieringen, N, Bel, A, Hulshof, MCCM & Alderliesten, T . Dosimetric Benefits of Midposition Compared With Internal Target Volume Strategy for Esophageal Cancer Radiation Therapy. International journal of radiation oncology, biology, physics 2019;103:2:491-502 (Amsterdam UMC). 705. Jochems A, van der Kooij MK, Fiocco M, Schouwenburg MG, Aarts MJ, van Akkooi AC, van den Berkmortel FWPJ, Blank CU, van den Eertwegh AJM, Franken MG, de Groot JB, Haanen JBAG, Hospers GAP, Koornstra RH, Kruit WHJ, Louwman M, Piersma D, van Rijn RS, Suijkerbuijk KPM, Ten Tije AJ, Vreugdenhil G, Wouters MWJM, van Zeijl MCT, van der Hoeven KJM, Kapiteijn E. Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry. Cancers (Basel) 2019; 11:E1007 (13 pp) (Amsterdam UMC & NKI). 706. Johannesma PC, van de Beek I, van der Wel TJWT, Reinhard R, Rozendaal L, Starink TM, van Waesberghe JHTM, Horenblas S, Gille HJJP, Jonker MA, Meijers-Heijboer HEJ, Postmus PE, Houweling AC, van Moorselaar JRA. Renal imaging in 199 Dutch patients with Birt-Hogg-Dube syndrome: Screening compliance and outcome. PLoS One 2019; 14:e0212952 (NKI). 707. Johnstone PAS, Boulware D, Djajadiningrat R, Ottenhof S, Necchi A, Catanzaro M, Ye D, Zhu Y, Nicolai N, Horenblas S, Spiess PE. Primary Penile Cancer: The Role of Adjuvant Radiation Therapy in the Management of Extranodal Extension in Lymph Nodes. Eur Urol Focus 2019; 5:737-41 (NKI). 708. Jong MC, Lown A, Schats W, Otto HR, Jong M. Mapping the concept, content and outcome of wilderness therapy for childhood cancer survivors: protocol for a scoping review. BMJ Open 2019; 9:e030544 (NKI). 709. Jongeneel, G, Klausch, T, van Erning, FN, Vink, GR, Koopman, M, Punt, CJA, Greuter, MJE & Coupé, VMH . Estimating adjuvant treatment effects in Stage II colon cancer: Comparing the synthesis of randomized clinical trial data to real-world data. International journal of cancer. Journal international du cancer 2019 (Amsterdam UMC). 710. Jongerden, IP, Slev, VN, van Hooft, SM, Pasman, HR, Verdonck-de Leeuw, IM, de Veer, AJE, van Uden-Kraan, CF & Francke, AL . Self-Management Support in Patients With Incurable Cancer: How Confident Are Nurses?. Oncology Nursing Forum 2019;46:1:104-112 (Amsterdam UMC). 711. Joosse ME, Nederlof I, Walker LSK, Samsom JN. Tipping the balance: inhibitory checkpoints in intestinal homeostasis. Mucosal Immunol 2019; 12:21-35 (NKI). 712. Joosten, SPJ, Mizutani, T, Spaargaren, M, Clevers, H & Pals, ST . MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance. Gastroenterology 2019;157:4:1153-1155 (Amsterdam UMC). 713. Jung, H, Giusti, G, Fajkovic, H, Herrmann, T, Jones, R, Straub, M, Baard, J, Osther, PJRS & Brehmer, M . Consultation on UTUC, Stockholm 2018: aspects of treatment. World journal of urology 2019;37:11:2279-2287 (Amsterdam UMC). 714. Jung, W, Park, T, Kim, Y, Park, H, Han, Y, He, J, Wolfgang, CL, Blair, A, Rashid, MF, Kluger, MD, Su, GH, Chabot, JA, Yang, CY, Lou, W, Valente, R, del Chiaro, M, Shyr, YM, Wang, SE, van Huijgevoort, NCM, Besselink, MG, Yang, Y, Kim, H, Kwon, W, Kim, SW & Jang, JY . Validation of a nomogram to predict the risk of cancer in patients with intraductal papillary mucinous neoplasm and main duct dilatation of 10 mm or less. British journal of surgery 2019;106:13:1829-1836 (Amsterdam UMC). 715. Kaaij LJT, Mohn F, van der Weide RH, de Wit E, Buhler M. The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse. Cell 2019; 178:1437- 51 (NKI). 716. Kaalep, A, Burggraaff, CN, Pieplenbosch, S, Verwer, EE, Sera, T, Zijlstra, J, Hoekstra, OS, Oprea-Lager, DE & Boellaard, R . Quantitative implications of the updated EARL 2019 PET-CT performance standards. EJNMMI PHYSICS 2019;6:1:28 (Amsterdam UMC). 717. Kaçmaz, E, Heidsma, CM, Besselink, MGH, Dreijerink, KMA, Klümpen, H-J, Nieveen van Dijkum, EJM & Engelsman, AF . Treatment of Liver Metastases from Midgut Neuroendocrine Tumours: A Systematic Review and Meta-Analysis. Journal of clinical medicine 2019;8:3: (Amsterdam UMC). 718. Kahle, XU, Hovingh, M, Noordzij, W, Seitz, A, Diepstra, A, Visser, L, van den Berg, A, van Meerten, T, Huls, G, Boellaard, R, Kwee, TC & Nijland, M . Tumour necrosis as assessed with 18 F-FDG PET is a potential prognostic marker in diffuse large B cell lymphoma independent of MYC rearrangements. European Radiology 2019 (Amsterdam UMC). 719. Kalendralis, P, Traverso, A, Shi, Z, Zhovannik, I, Monshouwer, R, Starmans, MPA, Klein, S, Pfaehler, E, Boellaard, R, Dekker, A & Wee, L . Multicenter CT phantoms public dataset for radiomics reproducibility tests. Medical Physics 2019;46:3:1512-1518 (Amsterdam UMC). 720. Kamermans A, Planting KE, Jalink K, van Horssen J, de Vries HE. Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production. Glia 2019; 67:68-77 (NKI). 721. Kammeyer, A, Willemsen, KJ, Ouwerkerk, W, Bakker, WJ, Ratsma, D, Pronk, SD, Smit, NPM & Luiten, RM . Mechanism of action of 4-substituted phenols to induce vitiligo and antimelanoma immunity. Pigment cell & melanoma research 2019;32:4:540-552 (Amsterdam UMC). 722. Kampen KR, Fancello L, Girardi T, Rinaldi G, Planque M, Sulima SO, Loayza-Puch F, Verbelen B, Vereecke S, Verbeeck J, Op de Beeck J, Royaert J, Vermeersch P, Cassiman D, Cools J, Agami R, Fiers M, Fendt SM, De Keersmaecker K. Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells. Nat Commun 2019; 10:2542 (NKI). 723. Kampshoff, CS, Verdonck-de Leeuw, IM, van Oijen, MG, Sprangers, MA & Buffart, LM . Ecological momentary assessments among patients with cancer: A scoping review. European Journal of Cancer Care 2019;28:3: (Amsterdam UMC). 724. Kappert KDR, van Alphen MJA, Smeele LE, Balm AJM, van der Heijden F. Quantification of tongue mobility impairment using optical tracking in patients after receiving primary surgery or chemoradiation. PLoS One 2019; 14:e0221593 (Amsterdam UMC & NKI). 725. Kappert KDR, van Alphen MJA, van Dijk S, Smeele LE, Balm AJM, van der Heijden F. An interactive surgical simulation tool to assess the consequences of a partial glossectomy on a biomechanical model of the tongue. Comput Methods Biomech Biomed Engin 2019; 22:827-39 (Amsterdam UMC & NKI). 726. Karsten RT, Al-Mamgani A, Bril SI, Tjon-A-Joe S, van der Molen L, de Boer JP, Hilgers FJM, Smeele LE, van den Brekel MWM, Stuiver MM. Sarcopenia, a strong determinant for prolonged feeding tube dependency after chemoradiotherapy for head and neck cancer. Head Neck 2019; 41:4000-8 (Amsterdam UMC & NKI). 727. Karsten RT, Stuiver MM, van der Molen L, Navran A, de Boer JP, Hilgers FJM, Klop WMC, Smeele LE. From reactive to proactive tube feeding during chemoradiotherapy for head and neck cancer: A clinical prediction model-based approach. Oral Oncol 2019; 88:172-9 (Amsterdam UMC & NKI). 728. Kaspers, GJL . Acute myeloid leukaemia niche regulates response to L-asparaginase. British Journal of Haematology 2019;186:3:397-399 (Amsterdam UMC). 729. Kastelein AW, Vos LMC, de Jong KH, van Baal JOAM, Nieuwland R, van Noorden CJF, Roovers JWR, Lok CAR. Embryology, Anatomy, Physiology and Pathophysiology of the Peritoneum and the Peritoneal Vasculature. Semin Cell Dev Biol 2019; 92:27-36 (NKI). 730. Kastelijn EA, de Langen AJ, Peters BJM. Treatment of oncogene-driven non-small cell lung cancer. Curr Opin Pulm Med 2019; 25:300-7 (NKI). 731. Kastritis, E, Leblond, V, Dimopoulos, MA, Kimby, E, Staber, P, Kersten, MJ, Tedeschi, A & Buske, C . Waldenström's macroglobulinaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of oncology 2019;30:5:860-862 (Amsterdam UMC). 732. Kater AP, van Oers MHJ, van Norden Y, van der Straten L, Driessen J, Posthuma WFM, Schipperus M, Chamuleau MED, Nijland M, Doorduijn JK, Van Gelder M, Hoogendoorn M, De Croon F, Wittebol S, Kerst JM, Marijt EWA, Raymakers RAP, Schaafsma MR, Dobber JA, Kersting SA, Levin MD. Feasibility and efficacy of addition of individualized dose lenalidomide to chlorambucil and rituximab as first- line treatment in elderly and FCR-unfit patients with advanced chronic lymphocytic leukemia. Haematologica 2019; 104:147-54 (NKI). 733. Kater, AP & Brown, JR . Ibrutinib. lancet oncology 2019;20:1:43954 (Amsterdam UMC). 734. Kater, AP, Seymour, JF, Hillmen, P, Eichhorst, B, Langerak, AW, Owen, C, Verdugo, M, Wu, J, Punnoose, EA, Jiang, Y, Wang, J, Boyer, M, Humphrey, K, Mobasher, M & Kipps, TJ . Fixed Duration of Venetoclax-Rituximab in Relapsed/Refractory Chronic Lymphocytic Leukemia Eradicates Minimal Residual Disease and Prolongs Survival. Journal of clinical oncology 2019;37:4:269-277 (Amsterdam UMC). 735. Kato Y, Hou LB, Miyagi S, Nitta E, Aoyama K, Shinoda D, Yamazaki S, Kuribayashi W, Isshiki Y, Koide S, Si S, Saraya A, Matsuzaki Y, van Lohuizen M, Iwama A. Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche. Exp Hematol 2019; 76:24-37 (NKI). 736. Ke, Y, van Munster, SN, Xue, L, He, S, Zhang, Y, Dou, L, Liu, Y, Liu, X, Liu, Y, Li, W, Lv, N, Dawsey, SM, Weusten, BLAM, Bergman, JJGHM & Wang, G . Prospective study of endoscopic focal cryoballoon ablation for esophageal squamous cell neoplasia in China. Gastrointestinal endoscopy 2019;90:2:204-212 (Amsterdam UMC). 737. Keesman R, van de Lindt TN, Juan-Cruz C, van den Wollenberg W, van der Bijl E, Nowee ME, Sonke JJ, van der Heide UA, Fast MF. Correcting geometric image distortions in slice-based 4D-MRI on the MR- linac. Med Phys 2019; 46:3044-54 (NKI). 738. Keikes, L, de Vos-Geelen, J, de Groot, JWB, Punt, CJA, Simkens, LHJ, Trajkovic-Vidakovic, M, Portielje, JEA, Vos, AH, Beerepoot, LV, Hunting, CB, Koopman, M & van Oijen, MGH . Implementation, participation and satisfaction rates of a web-based decision support tool for patients with metastatic colorectal cancer. Patient education and counseling 2019;102:7:1331-1335 (Amsterdam UMC). 739. Kemeny N, Kurilova I, Li J, Camacho JC, Sofocleous CT. Liver-Directed and Systemic Therapies for Colorectal Cancer Liver Metastases. Cardiovasc Intervent Radiol 2019; 42:1240-54 (NKI). 740. Kemps, PG, Zondag, TC, Steenwijk, EC, Andriessen, Q, Borst, J, Vloemans, S, Roelen, DL, Voortman, LM, Verdijk, RM, van Noesel, CJM, Cleven, AHG, Hawkins, C, Lang, V, de Ru, AH, Janssen, GMC, Haasnoot, GW, Franken, KLMC, van Eijk, R, Solleveld-Westerink, N, van Wezel, T, Egeler, RM, Beishuizen, A, van Laar, JAM, Abla, O, van den Bos, C, van Veelen, PA & van Halteren, AGS . Apparent Lack of BRAFV600E Derived HLA Class I Presented Neoantigens Hampers Neoplastic Cell Targeting by CD8+ T Cells in Langerhans Cell Histiocytosis. Frontiers in immunology 2019;10::3045 (Amsterdam UMC). 741. Kendall, T, Verheij, J, Gaudio, E, Evert, M, Guido, M, Goeppert, B & Carpino, G . Anatomical, histomorphological and molecular classification of cholangiocarcinoma. Liver international 2019; 39 Suppl 1::43282 (Amsterdam UMC). 742. Kerkhof, M, Koekkoek, JAF, Vos, MJ, van den Bent, MJ, Taal, W, Postma, TJ, Bromberg, JEC, Kouwenhoven, MCM, Dirven, L, Reijneveld, JC & Taphoorn, MJB . Withdrawal of antiepileptic drugs in patients with low grade and anaplastic glioma after long-term seizure freedom: a prospective observational study. Journal of Neuro-Oncology 2019;142:3:463-470 (Amsterdam UMC). 743. Kerr KM, Thunnissen E, Dafni U, Finn SP, Bubendorf L, Soltermann A, Verbeken E, Biernat W, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Radonic T, Wilson J, De Luca G, Gray SG, Cheney R, Savic S, Martorell M, Muley T, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dziadziuszko R, Vansteenkiste J, Weder W, Polydoropoulou V, Geiger T, Kammler R, Peters S, Stahel R. A retrospective cohort study of PD-L1 prevalence, molecular associations and clinical outcomes in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape Project. Lung Cancer 2019; 131:95-103 (Amsterdam UMC & NKI). 744. Kersten, MJ, van Ettekoven, CN & Heijink, DIM . Unexpected neurologic complications following a novel lymphoma treatment 'expected' to give rise to neurologic toxicity. BMJ case reports 2019;12:11: (Amsterdam UMC). 745. Kho E, Dashtbozorg B, de Boer LL, Van de Vijver KK, Sterenborg HJCM, Ruers TJM. Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information. Biomed Opt Express 2019; 10:4496-515 (Amsterdam UMC & NKI). 746. Kho E, de Boer LL, Van de Vijver K, van Duijnhoven F, Vrancken Peeters MTFD, Sterenborg HJCM, Ruers TJ. Hyperspectral imaging for resection margin assessment during cancer surgery. Clin Cancer Res 2019; 25:3572-80 (Amsterdam UMC & NKI). 747. Kho, E, de Boer, LL, Post, AL, van de Vijver, KK, Jóźwiak, K, Sterenborg, HJCM & Ruers, TJM . Imaging depth variations in hyperspectral imaging: Development of a method to detect tumor up to the required tumor-free margin width. Journal of biophotonics 2019 (Amsterdam UMC). 748. Kho, E, de Boer, LL, van de Vijver, KK, van Duijnhoven, F, Peeters, M-JTFDV, Sterenborg, HJCM & Ruers, TJM . Hyperspectral imaging for resection margin assessment during cancer surgery. Clinical cancer research 2019;25:12:3572-3580 (Amsterdam UMC). 749. Khurshed, M, Molenaar, RJ & van Noorden, CJ . A simple in silico approach to generate gene- expression profiles from subsets of cancer genomics data. BioTechniques 2019;67:4:172-176 (Amsterdam UMC). 750. Kielbassa K, Vegna S, Ramirez C, Akkari L. Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers. Front Immunol 2019; 10:2215 (NKI). 751. Kim RQ, Geurink PP, Mulder MPC, Fish A, Ekkebus R, El Oualid F, van Dijk WJ, van Dalen D, Ovaa H, van Ingen H, Sixma TK. Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity. Nat Commun 2019; 10:231 (NKI). 752. Kim Y, Bismeijer T, Zwart W, Wessels LFA, Vis DJ. Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo. Nat Commun 2019; 10:5034 (NKI). 753. Kim, JY, Lee, KH, Eisenhut, M, van der Vliet, HJ, Kronbichler, A, Jeong, GH, Shin, JI & Gamerith, G . Efficacy of cancer immunotherapy: An umbrella review of meta-analyses of randomized controlled trials. Cancers (Basel) 2019;11:11: (Amsterdam UMC). 754. Kishan, AU, Wang, X, Seiferheld, W, Collette, L, Sandler, KA, Sandler, HM, Bolla, M, Maingon, P, de Reijke, T, Hanks, GE, Nickols, NG, Rettig, M, Drakaki, A, Reiter, RE, Spratt, DE, Kupelian, PA, Steinberg, ML & King, CR . Association of Gleason Grade with Androgen Deprivation Therapy Duration and Survival Outcomes: A Systematic Review and Patient-Level Meta-analysis. JAMA oncology 2019;5:1:91-96 (Amsterdam UMC). 755. Klatte T, Gallagher KM, Afferi L, Volpe A, Kroeger N, Ribback S, McNeill A, Riddick ACP, Armitage JN, 'Aho TF, Eisen T, Fife K, Bex A, Pantuck AJ, Stewart GD. The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort. BMC Med 2019; 17:182 (NKI). 756. Klaver CEL, Wisselink DD, Punt CJA, Snaebjornsson P, Crezee J, Aalbers AGJ, Brandt A, Bremers AJA, Burger JWA, Fabry HFJ, Ferenschild F, Festen S, van Grevenstein WMU, Hemmer PHJ, de Hingh IHJT, Kok NFM, Musters GD, Schoonderwoerd L, Tuynman JB, van de Ven AWH, van Westreenen HL, Wiezer MJ, Zimmerman DDE, van Zweeden AA, Dijkgraaf MGW, Tanis PJ, COLOPEC collaborators group. Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial. Lancet Gastroenterol Hepatol 2019; 4:761-70 (Amsterdam UMC & NKI). 757. Klawer EME, van Houdt PJ, Simonis FFJ, van den Berg CAT, Pos FJ, Heijmink SWTP, Isebaert S, Haustermans K, van der Heide UA. Improved repeatability of dynamic contrast-enhanced MRI using the complex MRI signal to derive arterial input functions: a test-retest study in prostate cancer patients. Magn Reson Med 2019; 81:3358-69 (NKI). 758. Kleijn, G, van Uden-Kraan, CF, Bohlmeijer, ET, Becker-Commissaris, A, Pronk, M, Willemsen, V, Cuijpers, P & Verdonck-de Leeuw, IM . Patients’ experiences of life review therapy combined with memory specificity training (LRT-MST) targeting cancer patients in palliative care. Supportive Care in Cancer 2019;27:9:3311-3319 (Amsterdam UMC). 759. Kleijwegt, FS, Roda, AA, Rolvink, J, Kater, AP, Kersten, MJ & Vos, JMI . Rare but Serious. HemaSphere 2019;3:6:e307 (Amsterdam UMC). 760. Klein Nulent, TJW, van Es, RJJ, Valstar, MH, Smeele, LE, Smit, LA, Klein Gunnewiek, R, Zuithoff, NPA, de Keizer, B, de Bree, R & Willems, S . High CXCR4 expression in adenoid cystic carcinoma of the head and neck is associated with increased risk of locoregional recurrence. Journal of clinical pathology 2019 (Amsterdam UMC). 761. Klein, K, van Litsenburg, RRL, de Haas, V, Dors, N, van den Heuvel-Eibrink, MM, Knops, RRG, Tissing, WJE, Versluys, BA, Zwaan, CM & Kaspers, GJL . Causes of early death and treatment-related death in newly diagnosed pediatric acute myeloid leukemia: Recent experiences of the Dutch Childhood Oncology Group. Pediatric blood & cancer 2019 (Amsterdam UMC). 762. KleinJan GH, Sikorska K, Korne CM, Brouwer OR, Buckle T, Tillier C, van der Roest RCM, de Jong J, van Leeuwen FWB, van der Poel HG. A prediction model relating the extent of intraoperative fascia preservation to erectile dysfunction after nerve-sparing robot-assisted radical prostatectomy. J Robot Surg 2019; 13:455-62 (NKI). 763. Klevebro, F, Elliott, JA, Slaman, A, Vermeulen, BD, Kamiya, S, Rosman, C, Gisbertz, SS, Boshier, PR, Reynolds, JV, Rouvelas, I, Hanna, GB, van Berge Henegouwen, MI & Markar, SR . Cardiorespiratory Comorbidity and Postoperative Complications following Esophagectomy: a European Multicenter Cohort Study. Annals of surgical oncology 2019;26:9:2864-2873 (Amsterdam UMC). 764. Kloos, RQH, Pieters, R, van den Bos, C, van Eijkelenburg, NKA, de Jonge, R & van der Sluis, IM . The effect of asparaginase therapy on methotrexate toxicity and efficacy in children with acute lymphoblastic leukemia. Leukemia & lymphoma 2019;60:12:3002-3010 (Amsterdam UMC). 765. Klop WMC, Elshot YS, Beck ACC, Brandsen RE, Lohuis PJFM. Oncodermatology of the Head and Neck. Facial Plast Surg 2019; 35:368-76 (Amsterdam UMC & NKI). 766. Kneppers J, Krijgsman O, Melis M, de Jong J, Peeper DS, Bekers E, van der Poel HG, Zwart W, Bergman AM. Frequent clonal relations between metastases and non-index prostate cancer lesions. JCI Insight 2019; 4:e124756(NKI). 767. Kochan, JA, van den Belt, M, von der Lippe, J, Desclos, ECB, Steurer, B, Hoebe, RA, Scutigliani, EM, Verhoeven, J, Stap, J, Bosch, R, Rijpkema, M, van Oven, C, van Veen, HA, Stellingwerf, I, Vriend, LEM, Marteijn, JA, Aten, JA & Krawczyk, PM . Ultra-soft X-ray system for imaging the early cellular responses to X-ray induced DNA damage. Nucleic acids research 2019;47:17:e100 (Amsterdam UMC). 768. Kocian P, de Haan J, Cardonick EH, Uzan C, Lok CAR, Fruscio R, Halaska MJ, Amant F. Management and outcome of colorectal cancer during pregnancy: report of 41 cases. Acta Chir Belg 2019; 119:166-75 (NKI). 769. Koedam, TWA, Veltcamp Helbach, M, Penna, M, Wijsmuller, A, Doornebosch, P, van Westreenen, HL, Hompes, R, Bonjer, HJ, Sietses, C, de Graaf, E & Tuynman, JB . Short-term outcomes of transanal completion total mesorectal excision (cTaTME) for rectal cancer: a case-matched analysis. Surgical Endoscopy 2019;33:1:103-109 (Amsterdam UMC). 770. Koemans WJ, Chalabi M, van Sandick JW, van Dieren JM, Kodach LL. Beyond the PD-L1 horizon: in search for a good biomarker to predict success of immunotherapy in gastric and esophageal adenocarcinoma. Cancer Lett 2019; 442:279-86 (NKI). 771. Koemans WJ, van der Kaaij RT, Boot H, Buffart T, Veenhof AAFA, Hartemink KJ, Grootscholten C, Snaebjornsson P, Retel VP, Van Tinteren H, Vanhoutvin S, van der Noort V, Houwink A, Hahn C, Huitema ADR, Lahaye M, Los M, van den Barselaar P, Imhof O, Aalbers A, van Dam GM, van Etten B, Wijnhoven BPL, Luyer MDP, Boerma D, van Sandick JW. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy versus palliative systemic chemotherapy in stomach cancer patients with peritoneal dissemination, the study protocol of a multicentre randomised controlled trial (PERISCOPE II). BMC Cancer 2019; 19:420 (NKI). 772. Koenders, STA, Wijaya, LS, Erkelens, MN, Bakker, AT, van der Noord, VE, van Rooden, EJ, Burggraaff, L, Putter, PC, Botter, E, Wals, K, van den Elst, H, den Dulk, H, Florea, BI, van de Water, B, van Westen, GJP, Mebius, RE, Overkleeft, HS, Le Dévédec, SE & van der Stelt, M . Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells. ACS Central Science 2019;5:12:1965-1974 (Amsterdam UMC). 773. Kok JL, Teepen JC, van der Pal HJ, van Leeuwen FE, Tissing WJE, Neggers SJCM, Loonen JJ, Louwerens M, Versluys B, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Jaspers MMW, van Santen HM, van der Heiden-van der Loo M, Janssens GO, Maduro JH, Bruggink AH, Jongmans MC, Kremer LCM, Ronckers CM. Incidence of and Risk Factors for Histologically Confirmed Solid Benign Tumors Among Long-term Survivors of Childhood Cancer. JAMA Oncol 2019; 5:671-80 (NKI). 774. Kok JL, Teepen JC, van Leeuwen FE, Tissing WJE, Neggers SJCM, van der Pal HJ, Loonen JJ, Bresters D, Versluys B, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, van der Heiden-van der Loo M, Aleman BMP, Daniels LA, Haasbeek CJA, Hoeben B, Janssens GO, Maduro JH, Oldenburger F, van Rij C, Tersteeg RJHA, Hauptmann M, Kremer LCM, Ronckers CM. Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age. Neuro Oncol 2019; 21:392-403 (NKI). 775. Kok M, Chalabi M, Haanen J. How I treat MSI cancers with advanced disease. ESMO Open 2019; 4:e000511 (NKI). 776. Kok M, Winer E, Loi S. Passion for Immune checkpoint blockade in triple negative breast cancer? Comment on the IMpassion130 study. Ann Oncol 2019; 30:13-6 (NKI). 777. Kok, DE, van den Berg, MMGA, Posthuma, L, van ’t Erve, I, van Duijnhoven, FJB, de Roos, WK, Grosfeld, S, Los, M, Sommeijer, DW, van Laarhoven, HWM, Winkels, RM & Kampman, E . Changes in Circulating Levels of 25-hydroxyvitamin D3 in Breast Cancer Patients Receiving Chemotherapy. Nutrition and cancer 2019;71:5:756-766 (Amsterdam UMC). 778. Kok, HP, van Dijk, IWEM, Crama, KF, Franken, NAP, Rasch, CRN, Merks, JHM, Crezee, J, Balgobind, BV & Bel, A . Re-irradiation plus hyperthermia for recurrent pediatric sarcoma; a simulation study to investigate feasibility. International journal of oncology 2019;54:1:209-218 (Amsterdam UMC). 779. Kok, JL, Teepen, JC, van der Pal, HJ, van Leeuwen, FE, Tissing, WJE, Neggers, SJCMM, Loonen, JJ, Louwerens, M, Versluys, B, van den Heuvel-Eibrink, MM, van Dulmen-den Broeder, E, Jaspers, MMW, van Santen, HM, van der Heiden-van der Loo, M, Janssens, GO, Maduro, JH, Bruggink, AH, Jongmans, MC, Kremer, LCM & Ronckers, CCM . Incidence of and Risk Factors for Histologically Confirmed Solid Benign Tumors among Long-term Survivors of Childhood Cancer. JAMA oncology 2019;5:5:671-680 (Amsterdam UMC). 780. Kok, JL, Teepen, JC, van Leeuwen, FE, Tissing, WJE, Neggers, SJCMM, van der Pal, HJ, Loonen, JJ, Bresters, D, Versluys, B, van den Heuvel-Eibrink, MM, van Dulmen-den Broeder, E, van der Heiden- van der Loo, M, Aleman, BMP, Daniels, LA, Haasbeek, CJA, Hoeben, B, Janssens, GO, Maduro, JH, Oldenburger, F, van Rij, C, Tersteeg, RJHA, Hauptmann, M, Kremer, LCM, Ronckers, CCM, van den Berg, MH, Bruggink, AH, Caron, HN, Dolsma, WV, Grootenhuis, MA, den Hartogh, JG, Hollema, N, Jongmans, MC, Jaspers, MWM, Postma, A & van de Vijver, MJ . Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: Contributions of radiation dose, exposed cranial volume, and age. Neuro-Oncology 2019;21:3:392-403 (Amsterdam UMC & NKI). 781. Kolinger GD, Vallez GD, Kramer GM, Frings V, Smit EF, de Langen AJ, Dierckx RAJO, Hoekstra OS, Boellaard R. Repeatability of [(18)F]FDG PET/CT total metabolic active tumour volume and total tumour burden in NSCLC patients. EJNMMI Res 2019; 9:14 (NKI). 782. Kolinger, GD, Vállez García, D, Kramer, GM, Frings, V, Smit, EF, de Langen, AJ, Dierckx, RAJO, Hoekstra, OS & Boellaard, R . Repeatability of [ 18 F]FDG PET/CT total metabolic active tumour volume and total tumour burden in NSCLC patients. EJNMMI Research 2019;9:14.: (Amsterdam UMC). 783. Komen MMC, van den Hurk CJG, Nortier JWR, van der Ploeg T, Nieboer P, van der Hoeven JJM, Smorenburg CH. Prolonging the duration of post-infusion scalp cooling in the prevention of anthracycline-induced alopecia: a randomised trial in patients with breast cancer treated with adjuvant chemotherapy. Support Care Cancer 2019; 27:1919-25 (NKI). 784. Konert T, Vogel WV, Paez D, Polo A, Fidarova E, Carvalho H, Duarte PS, Zuliani AC, Santos AO, Altuhhova D, Karusoo L, Kapoor R, Sood A, Khader J, Al-Ibraheem A, Numair Y, Abubaker S, Soydal C, Kutuk T, Le TA, Canh NX, Bieu BQ, Ha LN, Belderbos JSA, MacManus MP, Thorwarth D, Hanna GG. Introducing FDG PET/CT-guided chemoradiotherapy for stage III NSCLC in low- and middle-income countries: preliminary results from the IAEA PERTAIN trial. Eur J Nucl Med Mol Imaging 2019; 46:2235-43 (NKI). 785. Kooijmans, ECM, Bökenkamp, A, Tjahjadi, NS, Tettero, JM, van Dulmen-den Broeder, E, van der Pal, HJH & Veening, MA . Early and late adverse renal effects after potentially nephrotoxic treatment for childhood cancer. Cochrane Database of Systematic Reviews 2019;2019:3: (Amsterdam UMC). 786. Koole SN, van Driel WJ, Sonke GS. Hyperthermic intraperitoneal chemotherapy for ovarian cancer: The heat is on. Cancer 2019; 125 Suppl 24:4587-93 (NKI). 787. Koole SN, van Lieshout C, van Driel WJ, van Schagen E, Sikorska K, Kieffer JM, Schagen van Leeuwen JH, Schreuder HWR, Hermans RH, de Hingh I, van der Velden J, Arts HJ, Massuger LFAG, Aalbers AG, Verwaal VJ, Van de Vijver K, Aaronson NK, Van Tinteren H, Sonke GS, van Harten WH, Retel VP. Cost Effectiveness of Interval Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer on the Basis of a Randomized Phase III Trial. J Clin Oncol 2019; 37:2041-50 (Amsterdam UMC & NKI). 788. Kooreman ES, van Houdt PJ, Nowee ME, van Pelt V, Tijssen RHN, Paulson ES, Gurney-Champion OJ, Wang J, Koetsveld F, van Buuren LD, Ter Beek LC, van der Heide UA. Feasibility and accuracy of quantitative imaging on a 1. 5 T MR-linear accelerator(Amsterdam UMC & NKI). 789. Kooyker, AI, Toes-Zoutendijk, E, Opstal-van Winden, AWJ, Spaander, MCW, Buskermolen, M, van Vuuren, HJ, Kuipers, EJ, van Kemenade, FJ, Ramakers, C, Thomeer, MGJ, Dekker, E, Nagtegaal, ID, de Koning, HJ, van Leerdam, ME & Lansdorp-Vogelaar, I . The second round of the Dutch colorectal cancer screening program: Impact of an increased fecal immunochemical test cut-off level on yield of screening. International journal of cancer. Journal international du cancer 2019 (Amsterdam UMC). 790. Kopetz S, Grothey A, Yaeger R, Van Cutsem E, Desai J, Yoshino T, Wasan H, Ciardiello F, Loupakis F, Hong YS, Steeghs N, Guren TK, Arkenau HT, Garcia-Alfonso P, Pfeiffer P, Orlov S, Lonardi S, Elez E, Kim TW, Schellens JHM, Guo C, Krishnan A, Dekervel J, Morris V, Calvo FA, Tarpgaard LS, Braun M, Gollerkeri A, Keir C, Maharry K, Pickard M, Christy-Bittel J, Anderson L, Sandor V, Tabernero J. Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer. N Engl J Med 2019; 381:1632-43 (NKI). 791. Kopper O, de Witte CJ, Lohmussaar K, Valle-Inc, Hami N, Kester L, Balgobind AV, Korving J, Proost N, Begthel H, van Wijk LM, Revilla SA, Theeuwsen R, van de Ven M, van Roosmalen MJ, Ponsioen B, Ho VWH, Neel BG, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG, van Diest PJ, Witteveen PO, Jonges T, Bos JL, van Oudenaarden A, Zweemer RP, Snippert HJG, Kloosterman WP, Clevers H. An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity. Nat Med 2019; 25:838-49 (NKI). 792. Korkmaz G, Manber Z, Lopes R, Prekovic S, Schuurman K, Kim Y, Teunissen H, Flach K, de Wit E, Galli GG, Zwart W, Elkon R, Agami R. A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation. Nucleic Acids Res 2019; 47:9557-72 (NKI). 793. Korsten, LHA, Jansen, F, de Haan, BJF, Sent, D, Cuijpers, P, Leemans, CR & Verdonck-de Leeuw, IM . Factors associated with depression over time in head and neck cancer patients: A systematic review. Psycho-Oncology 2019;28:6:1159-1183 (Amsterdam UMC). 794. Koster BD, Santegoets SJAM, Harting J, Baars A, van Ham SM, Scheper RJ, Hooijberg E, de Gruijl TD, van den Eertwegh AJM. Autologous tumor cell vaccination combined with systemic CpG-B and IFN- alpha promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial. Cancer Immunol Immunother 2019; 68:1025-35 (Amsterdam UMC & NKI). 795. Koster, J & Plasterk, RHA . A library of Neo Open Reading Frame peptides (NOPs) as a sustainable resource of common neoantigens in up to 50% of cancer patients. Scientific reports 2019;9:1: (Amsterdam UMC). 796. Kostou T, Papadimitroulas P, Papaconstadopoulos P, Devic S, Seuntjens J, Kagadis GC. Size-specific dose estimations for pediatric chest, abdomen/pelvis and head CT scans with the use of GATE. Phys Med 2019; 65:181-90 (NKI). 797. Kotsias, M, Blanas, A, van Vliet, SJ, Pirro, M, Spencer, DIR & Kozak, RP . Method comparison for N- glycan profiling: Towards the standardization of glycoanalytical technologies for cell line analysis. PLoS ONE 2019;14:10: (Amsterdam UMC). 798. Kozlovski I, Agami R. More or less - the same? mRNA fluctuations are balanced during translation. EMBO J 2019; 38:e103651 (NKI). 799. Kraaijenga SA, Hamming-Vrieze O, Verheijen S, Lamers E, van der Molen L, Hilgers FJ, van den Brekel MW, Heemsbergen WD. Radiation dose to the masseter and medial pterygoid muscle in relation to trismus after chemoradiotherapy for advanced head and neck cancer. Head Neck 2019; 41:1387-94 (NKI). 800. Kraaijpoel N, Bleker SM, Meyer G, Mahe I, Munoz A, Bertoletti L, Bartels-Rutten A, Beyer- Westendorf J, Porreca E, Boulon C, van Es N, Iosub DI, Couturaud F, Biosca M, Lerede T, Lacroix P, Maraveyas A, Aggarwal A, Girard P, Buller HR, Di Nisio M. Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With Cancer: An International Prospective Cohort Study. J Clin Oncol 2019; 37:1713-20 (NKI). 801. Kraal, KCJM, Timmerman, I, Kansen, HM, van den Bos, C, Zsiros, J, van den Berg, H, Somers, S, Braakman, E, Peek, AML, van Noesel, MM, van der Schoot, CE, Fiocco, M, Caron, HN, Voermans, C & Tytgat, GAM . Peripheral stem cell apheresis is feasible post 131iodine-metaiodobenzylguanidine- therapy in high-risk neuroblastoma, but results in delayed platelet reconstitution. Clinical cancer research 2019;25:3:1012-1021 (Amsterdam UMC). 802. Kramer GM, Yaqub M, Vargas HA, Schuit R, Windhorst AD, van den Eertwegh A, van der Veldt A, Bergman A, Burnazi E, Lewis JS, Chua SS, Staton K, Beattie BJ, Humm JL, Davis ID, Weickhardt A, Scott A, Morris MJ, Hoekstra OS, Lammertsma AA. Assessment of simplified methods for quantification of (18)F-FDHT uptake in patients with metastatic castration-resistant prostate cancer. J Nucl Med 2019; 60:1221-7 (Amsterdam UMC & NKI). 803. Kramer I, Schaapveld M, Oldenburg HSA, Sonke GS, McCool D, van Leeuwen FE, Van de Vijver KK, Russell NS, Linn SC, Siesling S, Menke-van der Houven van Oordt CW, Schmidt MK. The influence of adjuvant systemic regimens on contralateral breast cancer risk and receptor subtype. J Natl Cancer Inst 2019; 111:djz010 (Amsterdam UMC & NKI). 804. Krdzalic J, Maas M, Gollub MJ, Beets-Tan RGH. Guidelines for MR imaging in rectal cancer: Europe versus United States. Abdom Radiol (NY) 2019; 44:3498-507 (NKI). 805. Kreft S, Gesierich A, Eigentler T, Franklin C, Valpione S, Ugurel S, Utikal J, Haferkamp S, Blank C, Larkin J, Garbe C, Schadendorf D, Lorigan P, Schilling B. Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma. Eur J Cancer 2019; 116:207-15 (NKI). 806. Kremer WW, Berkhof J, Bleeker MC, Heideman DA, van Trommel NE, van Baal MW, Verhoeve HR, Meijer CJ, Kenter GG. Role of FAM19A4/miR124-2 methylation analysis in predicting regression or non-regression of CIN2/3 lesions: a protocol of an observational longitudinal cohort study. BMJ Open 2019; 9:e029017 (Amsterdam UMC & NKI). 807. Kremer, WW, Berkhof, J, Bleeker, MCG, Heideman, DAM, van Trommel, NE, van Baal, MW, Verhoeve, HR, Meijer, CJLM & Kenter, GG . Role of FAM19A4/miR124-2 methylation analysis in predicting regression or non-regression of CIN2/3 lesions: A protocol of an observational longitudinal cohort study. BMJ open 2019;9:7: (Amsterdam UMC & NKI). 808. Kremer, WW, van Zummeren, M, Breytenbach, E, Richter, KL, Steenbergen, RDM, Meijer, CJLM & Dreyer, G . The use of molecular markers for cervical screening of women living with HIV in South Africa. AIDS 2019;33:13:2035-2042 (Amsterdam UMC). 809. Krenning L, van den Berg J, Medema RH. Life or Death after a Break: What Determines the Choice? Mol Cell 2019; 76:346-58 . (NKI). 810. Kreutzman, A, Yadav, B, Brummendorf, TH, Gjertsen, BT, Lee Hee, M, Janssen, J, Kasanen, T, Koskenvesa, P, Lofti, K, Markevärn, B, Olsson-Strömberg, U, Stentoft, J, Stenke, L, Söderlund, S, Udby, L, Richter, J, Hjorth-Hansen, H & Mustjoki, S . Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line. OncoImmunology 2019;8:9: (Amsterdam UMC). 811. Krikken, E, van der Kemp, WJM, Khlebnikov, V, van Dalen, T, Los, M, van Laarhoven, HWM, Luijten, PR, van den Bosch, MAAJ, Klomp, DWJ & Wijnen, JP . Contradiction between amide-CEST signal and pH in breast cancer explained with metabolic MRI. NMR in biomedicine 2019;32:8: (Amsterdam UMC). 812. Krikken, E, van der Kemp, WJM, van Diest, PJ, van Dalen, T, van Laarhoven, HWM, Luijten, PR, Klomp, DWJ & Wijnen, JP . Early detection of changes in phospholipid metabolism during neoadjuvant chemotherapy in breast cancer patients using phosphorus magnetic resonance spectroscopy at 7T. NMR in biomedicine 2019 (Amsterdam UMC). 813. Krimpenfort P, Snoek M, Lambooij JP, Song JY, van der Weide R, Bhaskaran R, Teunissen H, Adams DJ, de Wit E, Berns A. A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis. Nat Commun 2019; 10:1425 (NKI). 814. Kristensen, BW, Priesterbach-Ackley, LP, Petersen, JK & Wesseling, P . Molecular pathology of tumors of the central nervous system. Annals of Oncology 2019;30:8:1265-1278 (Amsterdam UMC). 815. Kroon P, Frijlink E, Iglesias-Guimarais V, Volkov A, Van Buuren MM, Schumacher TN, Verheij M, Borst J, Verbrugge I. Radiotherapy and Cisplatin Increase Immunotherapy Efficacy by Enabling Local and Systemic Intratumoral T-cell Activity. Cancer Immunol Res 2019; 7:670-82 (Amsterdam UMC & NKI). 816. Kroon, HM, Collaborators: The PelvEx Collaborative:, Dudi-Venkata, NN, Bedrikovetski, S, Thomas, ML, Kelly, ME, Aalbers, AGJ, Abdul Aziz, N, Abraham-Nordling, M, Akiyoshi, T, Alberda, W, Andric, M, Antoniou, A, Austin, KK, Baker, RP, Bali, M, Baseckas, G, Bednarski, BK, Beets, GL, Berg, PL, Beynon, J, Biondo, S, Bordeianou, L, Brunner, M, Buchwald, P, Burger, JWA, Burling, D, Campain, N, Chan, KKL, Chang, GJ, Chew, MH, C Chong, P, Christensen, HK, Codd, M, Colquhoun, AJ, Corr, A, Coscia, M, Coyne, PE, Creavin, B, Damjanovic, L, Daniels, IR, Davies, M, Davies, RJ, de Wilt, JHW, Kusters, M, Lee, P, Meijerink, WJHJ, Mehta, AM, Rutten, HJT, Tuynman, JB, van Ramshorst, GH, Yip, J & Sammour, T . Palliative pelvic exenteration: A systematic review of patient-centered outcomes. European Journal of Surgical Oncology 2019;45:10:1787-1795 (Amsterdam UMC). 817. Kruizinga R, Scherer-Rath M, Schilderman JB, Hartog ID, Van Der Loos JP, Kotze HP, Westermann AM, Klumpen HJ, Kortekaas F, Grootscholten C, Bossink F, Schrama J, Van De Vrande W, Blokland W, De Vos FY, Kuin A, Meijer WG, Van Oijen MG, Sprangers MA, Van Laarhoven HW. An assisted structured reflection on life events and life goals in advanced cancer patients: Outcomes of a randomized controlled trial (Life InSight Application (LISA) study). Palliat Med 2019; 33:221-31 (Amsterdam UMC & NKI). 818. Kuijvenhoven, JC, Livi, V, Morandi, L, Cancellieri, A, Annema, JT & Trisolini, R . The expanding role of endobronchial ultrasound in patients with centrally located intrapulmonary tumors. Lung cancer (Amsterdam, Netherlands) 2019;134::194-201. (Amsterdam UMC). 819. Kumar, MS, Yadav, TT, Khair, RR, Peters, GJ & Yergeri, MC . Combination Therapies of Artemisinin and its Derivatives as a Viable Approach for Future Cancer Treatment. Current pharmaceutical design 2019;25:31:3323-3338 (Amsterdam UMC). 820. Kumar, R, van de Vijver, M, Tortora, G, Ciardiello, F, Goldkorn, T, Miller, WH & Norton, L . A tribute to John Mendelsohn: A pioneer in targeted cancer therapy. Cancer research 2019;79:17:4315-4323 (Amsterdam UMC). 821. Kuninty, PR, Bansal, R, de Geus, SWL, Mardhian, DF, Schnittert, J, van Baarlen, J, Storm, G, Bijlsma, MF, van Laarhoven, HW, Metselaar, JM, Kuppen, PJK, Vahrmeijer, AL, Östman, A, Sier, CFM & Prakash, J . ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer. Science advances 2019;5:9: (Amsterdam UMC). 822. Kurilova I, Beets-Tan RGH, Flynn J, Gonen M, Ulaner G, Petre EN, Boas FE, Ziv E, Yarmohammadi H, Klompenhouwer EG, Cercek A, Kemeny NA, Sofocleous CT. Factors Affecting Oncologic Outcomes of 90Y Radioembolization of Heavily Pre-Treated Patients With Colon Cancer Liver Metastases. Clin Colorectal Cancer 2019; 18:8-18 (NKI). 823. Kurk, S, Peeters, P, Stellato, R, Dorresteijn, B, de Jong, P, Jourdan, M, Creemers, G-J, Erdkamp, F, de Jongh, F, Kint, P, Simkens, L, Tanis, B, Tjin-A-Ton, M, van der Velden, A, Punt, C, Koopman, M & May, A . Skeletal muscle mass loss and dose-limiting toxicities in metastatic colorectal cancer patients. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE 2019;10:4:803-813 (Amsterdam UMC). 824. Kurk, SA, Stellato, RK, Peeters, PHM, Dorresteijn, B, Jourdan, M, Oskam, MJ, Punt, CJA, Koopman, M & May, AM . Trajectory of body mass and skeletal muscle indices and disease progression in metastatic colorectal cancer patients. The American journal of clinical nutrition 2019;110:6:1395- 1403 (Amsterdam UMC). 825. Kuusk T, Brouwer O, Graafland N, Hendricksen K, Donswijk M, Bex A. Sentinel-lymph node biopsy in renal tumours- surgical technique and safety. Urology 2019; 130:186-90 (NKI). 826. Kwakman JJM, van Werkhoven E, Simkens LHJ, van Rooijen JM, van de Wouw YAJ, Tije AJT, Creemers GM, Hendriks MP, Los M, van Alphen RJ, Polee MB, Muller EW, van der Velden AMT, van Voorthuizen T, Koopman M, Mol L, Punt CJA. Updated Survival Analysis of the Randomized Phase III Trial of S-1 Versus Capecitabine in the First-Line Treatment of Metastatic Colorectal Cancer by the Dutch Colorectal Cancer Group. Clin Colorectal Cancer 2019; 18:e229-e230 [Letter] (NKI). 827. Kwakman, JJM, van Kruijsdijk, RCM, Elias, SG, Seymour, MT, Meade, AM, Visseren, FLJ, Punt, CJA & Koopman, M . Choosing the right strategy based on individualized treatment effect predictions. Acta oncologica (Stockholm, Sweden) 2019;58:3:326-333 (Amsterdam UMC). 828. Laaniste, L, Srivastava, PK, Stylianou, J, Syed, N, Cases-Cunillera, S, Shkura, K, Zeng, Q, Rackham, OJL, Langley, SR, Delahaye-Duriez, A, O. Integrated systems-genetic analyses reveal a network target for delaying glioma progression. Annals of Clinical and Translational Neurology 2019;6:9:1616-1638 (Amsterdam UMC). 829. Labeur, TA, Runge, JH, Klompenhouwer, EG, Klümpen, H-J, Takkenberg, RB & van Delden, OM . Diffusion-weighted imaging of hepatocellular carcinoma before and after transarterial chemoembolization: role in survival prediction and response evaluation. ABDOMINAL RADIOLOGY 2019;44:8:2740-2750 (Amsterdam UMC & NKI). 830. Labeur, TA, van Vugt, JLA, ten Cate, DWG, Takkenberg, RB, Ijzermans, JNM, Groot Koerkamp, B, de Man, RA, van Delden, OM, Eskens, FALM & Klümpen, H-J . Body Composition Is an Independent Predictor of Outcome in Patients with Hepatocellular Carcinoma Treated with Sorafenib. Liver Cancer 2019;8:4:255-270 (Amsterdam UMC). 831. Labrie, N, van Dulmen, S, Kersten, MJ, de Haes, HJCM, Pieterse, AH, van Weert, JCM, van Spronsen, DJ & Smets, EMA . Effective information provision about the side effects of treatment for malignant lymphoma: Protocol of a randomized controlled trial using video vignettes. Journal of medical Internet research 2019;21:5: (Amsterdam UMC). 832. Lac V, Verhoef L, guirre-Hernandez R, Nazeran TM, Tessier-Cloutier B, Praetorius T, Orr NL, Noga H, Lum A, Khattra J, Prentice LM, Co D, Kobel M, Mijatovic V, Lee AF, Pasternak J, Bleeker MC, Kramer B, Brucker SY, Kommoss F, Kommoss S, Horlings HM, Yong PJ, Huntsman DG, Anglesio MS. Iatrogenic endometriosis harbors somatic cancer-driver mutations. Hum Reprod 2019; 34:69-78 (NKI). 833. Lac, V, Verhoef, L, Aguirre-Hernandez, R, Nazeran, TM, Tessier-Cloutier, B, Praetorius, T, Orr, NL, Noga, H, Lum, A, Khattra, J, Prentice, LM, Co, D, Köbel, M, Mijatovic, V, Lee, AF, Pasternak, J, Bleeker, MC, Krämer, B, Brucker, SY, Kommoss, F, Kommoss, S, Horlings, HM, Yong, PJ, Huntsman, DG & Anglesio, MS . Iatrogenic endometriosis harbors somatic cancer-driver mutations. Human Reproduction 2019;34:1:69-78 (Amsterdam UMC). 834. Lagergren P, Schandl A, Aaronson NK, Adami HO, de Lorenzo.F., Denis L, Faithfull S, Liu L, Meunier F, Ulrich C. Cancer survivorship: an integral part of Europe's research agenda. Mol Oncol 2019; 13:624- 35 (NKI). 835. Laguna, MP . Re: Adjuvant Vascular Endothelial Growth Factor-Targeted Therapy in Renal Cell Carcinoma: A Systematic Review and Pooled Analysis. Journal of urology 2019;201:6:1050-1051 (Amsterdam UMC). 836. Laguna, MP . Re: Axitinib versus Placebo as an Adjuvant Treatment of Renal Cell Carcinoma: Results from the Phase III, Randomized ATLAS Trial. Journal of urology 2019;202:1:27-28 (Amsterdam UMC). 837. Laguna, MP . Re: Below Safety Limits, Every Unit of Glomerular Filtration Rate Counts: Assessing the Relationship between Renal Function and Cancer-Specific Mortality in Renal Cell Carcinoma. Journal of urology 2019;201:6:1049-1050 (Amsterdam UMC). 838. Laguna, MP . Re: Clonal Relatedness and Mutational Differences between Upper Tract and Bladder Urothelial Carcinoma. Journal of urology 2019;202:3:456-457 (Amsterdam UMC). 839. Laguna, MP . Re: Diagnostic Needle Biopsies in Renal Masses: Patient and Physician Perspectives. Journal of urology 2019;202:1:28-29 (Amsterdam UMC). 840. Laguna, MP . Re: Intensive Imaging-Based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-Recurrence Survival: Results from a European Multicentre Database (RECUR). Journal of urology 2019;202:3:455-456 (Amsterdam UMC). 841. Laguna, MP . Re: The Probability of Aggressive versus Indolent Histology Based on Renal Tumor Size: Implications for Surveillance and Treatment. Journal of urology 2019;201:5:856 (Amsterdam UMC). 842. Laguna, MP . Re: The Prognostic Value of the Site of Invasion in T3aN0M0 Clear Cell Renal Cell Carcinoma. Journal of urology 2019;202:5:863-864 (Amsterdam UMC). 843. Laguna, MP . Re: Time Trends in Service Provision and Survival Outcomes for Patients with Renal Cancer Treated by Nephrectomy in England 2000-2010. Journal of urology 2019;201:5:855 (Amsterdam UMC). 844. Laguna, MP . Re: Use of Delayed Intervention for Small Renal Masses Initially Managed with Active Surveillance. Journal of urology 2019;202:2:207 (Amsterdam UMC). 845. Laguna, MP . Re: Variability in Partial Nephrectomy Outcomes: Does Your Surgeon Matter?. Journal of urology 2019;202:2:206-207 (Amsterdam UMC). 846. Laheij, AMGA, Raber-Durlacher, JE, Koppelmans, RGA, Huysmans, M-CDNJM, Potting, C, van Leeuwen, SJM, Hazenberg, MD, Brennan, MT, von Bültzingslöwen, I, Johansson, J-E, de Soet, JJ, Haverman, TM, Buijs, MJ, Brandt, BW, Rozema, FR, Blijlevens, NMA & Zaura, E . Microbial changes in relation to oral mucositis in autologous hematopoietic stem cell transplantation recipients. Scientific reports 2019;9:1: (Amsterdam UMC). 847. Lakeman, IMM, Hilbers, FS, Rodríguez-Girondo, M, Lee, A, Vreeswijk, MPG, Hollestelle, A, Seynaeve, C, Meijers-Heijboer, H, Oosterwijk, JC, Hoogerbrugge, N, Olah, E, Vasen, HFA, van Asperen, CJ & Devilee, P . Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non- BRCA1/2 breast cancer families. Journal of Medical Genetics 2019;56:9:581-589 (Amsterdam UMC). 848. Lalani AA, McGregor BA, Albiges L, Choueiri TK, Motzer R, Powles T, Wood C, Bex A. Systemic Treatment of Metastatic Clear Cell Renal Cell Carcinoma in 2018: Current Paradigms, Use of Immunotherapy, and Future Directions. Eur Urol 2019; 75:100-10 (NKI). 849. Lam TBL, MacLennan S, Plass K, Willemse PM, Mason MD, Cornford P, Donaldson J, Davis NF, Dell'Oglio P, Fankhauser C, Grivas N, Ingels A, Lardas M, Liew M, Pang KH, Paterson C, Omar MI, Zattoni F, Buddingh KT, van den Broeck T, Cumberbatch MG, Fossati N, Gross T, Moris L, Schoots IG, van den Bergh RCN, Briers E, Fanti S, De Santis M, Gillessen S, Grummet JP, Henry AM, van der Poel HG, van der Kwast TH, Rouviere O, Tilki D, Wiegel T, N'Dow J, van Poppel H, Mottet N. Study Protocol for the DETECTIVE Study: An International Collaborative Study To Develop Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer. Eur Urol 2019; 75:699-702 [Letter] (NKI). 850. Lam TBL, MacLennan S, Willemse PM, Mason MD, Plass K, Shepherd R, Baanders R, Bangma CH, Bjartell A, Bossi A, Briers E, Briganti A, Buddingh KT, Catto JWF, Colecchia M, Cox BW, Cumberbatch MG, Davies J, Davis NF, De Santis M, Dell'Oglio P, Deschamps A, Donaldson JF, Egawa S, Fankhauser CD, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Gross T, Grummet JP, Henry AM, Ingels A, Irani J, Lardas M, Liew M, Lin DW, Moris L, Omar MI, Pang KH, Paterson CC, Renard-Penna R, Ribal MJ, Roobol MJ, Roupret M, Rouviere O, Sancho PG, Richenberg J, Schoots IG, Sedelaar JPM, Stricker P, Tilki D, Vahr LS, van den Bergh RCN, van den Broeck T, van der Kwast TH, van der Poel HG, van Leenders GJLH, Varma M, Violette PD, Wallis CJD, Wiegel T, Wilkinson K, Zattoni F, N'Dow JMO, van Poppel H, Cornford P, Mottet N. EAU-EANM-ESTRO-ESUR-SIOG Prostate Cancer Guideline Panel Consensus Statements for Deferred Treatment with Curative Intent for Localised Prostate Cancer from an International Collaborative Study (DETECTIVE Study). Eur Urol 2019; 76:790-813 (NKI). 851. Lamain-de Ruiter M, Kwee A, Naaktgeboren CA, Louhanepessy RD, De Groot I, Evers IM, Groenendaal F, Hering YR, Huisjes AJM, Kirpestein C, Monincx WM, Schielen PCJI, Van 't Zelfde A, Van Oirschot CM, Vankan-Buitelaar SA, Vonk MAAW, Wiegers TA, Zwart JJ, Moons KGM, Franx A, Koster MPH. External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort. Hypertens Pregnancy 2019; 38:78-88 (NKI). 852. Lambo, S, Gröbner, SN, Rausch, T, Waszak, SM, Schmidt, C, Gorthi, A, Romero, JC, Mauermann, M, Brabetz, S, Krausert, S, Buchhalter, I, Koster, J, Zwijnenburg, DA, Sill, M, Hübner, J-M, Mack, N, Schwalm, B, Ryzhova, M, Hovestadt, V, Papillon-Cavanagh, S, Chan, JA, Landgraf, P, Ho, B, Milde, T, Witt, O, Ecker, J, Sahm, F, Sumerauer, D, Ellison, DW, Orr, BA, Darabi, A, Haberler, C, Figarella- Branger, D, Wesseling, P, Schittenhelm, J, Remke, M, Taylor, MD, Gil-da-Costa, MJ, Łastowska, M, Grajkowska, W, Hasselblatt, M, Hauser, P, Pietsch, T, Uro-Coste, E, Bourdeaut, F, Masliah-Planchon, J, Rigau, V, Alexandrescu, S, Wolf, S, Li, X-N, Schüller, U, Snuderl, M, Karajannis, MA, Giangaspero, F, Jabado, N, von Deimling, A, Jones, DTW, Korbel, JO, von Hoff, K, Lichter, P, Huang, A, Bishop, AJR, Pfister, SM, Korshunov, A & Kool, M . The molecular landscape of ETMR at diagnosis and relapse. Nature 2019;576:7786:274-280 (Amsterdam UMC). 853. Lambrecht M, Clementel E, Sonke JJ, Nestle U, Adebahr S, Guckenberger M, Andratschke N, Weber DC, Verheij M, Hurkmans CW. Radiotherapy quality assurance of SBRT for patients with centrally located lung tumours within the multicentre phase II EORTC Lungtech trial: Benchmark case results. Radiother Oncol 2019; 132:63-9 (NKI). 854. Lambrecht M, Sonke JJ, Nestle U, Peulen H, Weber DC, Verheij M, Hurkmans CW. Quality assurance of four-dimensional computed tomography in a multicentre trial of stereotactic body radiotherapy of centrally located lung tumours. Phys Imag Radiat Oncol 2019; 8:57-62 (NKI). 855. Lambrecht ML, Eaton DJ, Sonke JJ, Nestle U, Peulen H, Weber DC, Verheij M, Hurkmans CW. Results of a multicentre dosimetry audit using a respiratory phantom within the EORTC LungTech trial. Radiother Oncol 2019; 138:106-13 (NKI). 856. Lambrecht, M, Clementel, E, Sonke, J-J, Nestle, U, Adebahr, S, Guckenberger, M, Andratschke, N, Weber, DC, Verheij, M & Hurkmans, CW . Radiotherapy quality assurance of SBRT for patients with centrally located lung tumours within the multicentre phase II EORTC Lungtech trial: Benchmark case results. Radiotherapy and Oncology 2019;132::63-69 (Amsterdam UMC). 857. Lambrecht, ML, Eaton, DJ, Sonke, J-J, Nestle, U, Peulen, H, Weber, DC, Verheij, M & Hurkmans, CW . Results of a multicentre dosimetry audit using a respiratory phantom within the EORTC LungTech trial. Radiotherapy and Oncology 2019;138::106-113 (Amsterdam UMC). 858. Lambregts DMJ, Boellaard TN, Beets-Tan RGH. Response evaluation after neoadjuvant treatment for rectal cancer using modern MR imaging: a pictorial review. Insights Imaging 2019; 10:15 (14 pp) (NKI). 859. Laméris, W, Eshuis, WJ, Cuesta, MA, Gisbertz, SS & van Berge Henegouwen, MI . Optimal mobilization of the stomach and the best place in the gastric tube for intrathoracic anastomosis. Journal of thoracic disease 2019;11:Suppl 5:S743-S749 (Amsterdam UMC). 860. Lange M, Joly F, Vardy J, Ahles T, Dubois M, Tron L, Winocur G, de Ruiter MB, Castel H. Cancer- Related Cognitive Impairment: An update on state of the art, detection, and management strategies in cancer survivors. Ann Oncol 2019; 30:1925-40 (NKI). 861. Lange, I, Koster, J & Koomoa, D-LT . Calcium signaling regulates fundamental processes involved in Neuroblastoma progression. Cell Calcium 2019;82::102052. (Amsterdam UMC). 862. Langedijk, AC, van Aalst, M, Meek, B, van Leeuwen, EMM, Zeerleder, S, Meijer, E, Hazenberg, MD, Grobusch, MP & Goorhuis, A . Long-term pneumococcal vaccine immunogenicity following allogeneic hematopoietic stem cell transplantation. Vaccine 2019;37:3:510-515 (Amsterdam UMC). 863. Langenhorst JB, Dorlo TPC, van Maarseveen EM, Nierkens S, Kuball J, Boelens JJ, van Kesteren C, Huitema ADR. Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation. Clin Pharmacokinet 2019; 58:627-37 (NKI). 864. Langenhorst JB, van Kesteren C, van Maarseveen EM, Dorlo TPC, Nierkens S, Lindemans CA, de Witte MA, van Rhenen A, Raijmakers R, Bierings M, Kuball J, Huitema ADR, Boelens JJ. Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes. Blood Adv 2019; 3:2179-87 (NKI). 865. Langton, S, Rijken, JA, Bankhead, CR, Plüddemann, A & Leemans, CR . Referrals for head and neck cancer in England and The Netherlands: an international qualitative study of the views of secondary- care surgical specialists. British Journal of Oral and Maxillofacial Surgery 2019;57:2:116-124 (Amsterdam UMC). 866. Lansu J, Groenewegen J, van Coevorden F, van Houdt W, van Akkooi ACJ, van Boven H, van de Sande M, Verheij M, Haas RL. Time dependent dynamics of wound complications after preoperative radiotherapy in Extremity Soft Tissue Sarcomas. Eur J Surg Oncol 2019; 45:684-90 (NKI). 867. Larcher A, De Naeyer G, Turri F, Dell'Oglio P, Capitanio U, Collins JW, Wiklund P, van der Poel H, Montorsi F, Mottrie A. The ERUS Curriculum for Robot-assisted Partial Nephrectomy: Structure Definition and Pilot Clinical Validation. Eur Urol 2019; 75:1023-31 (NKI). 868. Larcher A, Wallis CJD, Bex A, Blute ML, Ficarra V, Mejean A, Karam JA, van Poppel H, Pal SK. Individualised Indications for Cytoreductive Nephrectomy: Which Criteria Define the Optimal Candidates? Eur Urol Oncol 2019; 2:365-78 . (NKI). 869. Larghi, A, Ibrahim, M, Fuccio, L, Lekkerkerker, S, Eisendrath, P, Frazzoni, L, Fockens, P, la Marca, M, van Hooft, JE, Deviere, J & Costamagna, G . Forward-viewing echoendoscope versus standard echoendoscope for endoscopic ultrasound-guided tissue acquisition of solid lesions: A randomized, multicenter study. Endoscopy 2019;51:5:444-451 (Amsterdam UMC). 870. Larkin J, Brown MP, Arance AM, Hauschild A, Queirolo P, Vecchio MD, Ascierto PA, Krajsova I, Schachter J, Neyns B, Garbe C, Sileni VC, Mandala M, Gogas H, Espinosa E, Hospers G, Lorigan P, Nyakas M, Guminski A, Liszkay G, Rutkowski P, Miller W, Jr., Donica M, Makrutzki M, Blank C. An open-label, multicentre safety study of vemurafenib in patients with BRAF(V600)-mutant metastatic melanoma: final analysis and a validated prognostic scoring system. Eur J Cancer 2019; 107:175-85 (NKI). 871. Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Lao CD, Cowey CL, Schadendorf D, Wagstaff J, Dummer R, Ferrucci PF, Smylie M, Hogg D, Hill A, Marquez-Rodas I, Haanen J, Guidoboni M, Maio M, Schoffski P, Carlino MS, Lebbe C, McArthur G, Ascierto PA, Daniels GA, Long GV, Bastholt L, Rizzo JI, Balogh A, Moshyk A, Hodi FS, Wolchok JD. Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma. N Engl J Med 2019; 381:1535-46 (NKI). 872. Lassche, G, Crezee, J & van Herpen, CML . Whole-body hyperthermia in combination with systemic therapy in advanced solid malignancies. Critical reviews in oncology/hematology 2019;139::67-74. (Amsterdam UMC). 873. Lauseker, M, Bachl, K, Turkina, A, Faber, E, Prejzner, W, Olsson-Strömberg, U, Baccarani, M, Lomaia, E, Zackova, D, Ossenkoppele, G, Griskevicius, L, Schubert-Fritschle, G, Sacha, T, Heibl, S, Koskenvesa, P, Bogdanovic, A, Clark, RE, Guilhot, J, Hoffmann, VS, Hasford, J, Hochhaus, A & Pfirrmann, M . Prognosis of patients with chronic myeloid leukemia presenting in advanced phase is defined mainly by blast count, but also by age, chromosomal aberrations and hemoglobin. American Journal of Hematology 2019;94:11:1236-1243 (Amsterdam UMC). 874. Lavitrano M, Ianzano L, Bonomo S, Cialdella A, Cerrito MG, Pisano F, Missaglia C, Giovannoni R, Romano G, McLean CM, Voest EE, D'Amato F, Noli B, Ferri GL, Agostini M, Pucciarelli S, Helin K, Leone BE, Canzonieri V, Grassilli E. BTK inhibitors synergize with 5-FU to treat drug-resistant TP53- null colon cancers. J Pathol 2019; 250:134-47 (NKI). 875. Law, I, Albert, NL, Arbizu, J, Boellaard, R, Drzezga, A, Galldiks, N, la Fougère, C, Langen, K-J, Lopci, E, Lowe, V, McConathy, J, Quick, HH, Sattler, B, Schuster, DM, Tonn, J-C & Weller, M . Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:3:540-557 (Amsterdam UMC). 876. le Large, TYS, el Hassouni, B, Funel, N, Kok, B, Piersma, SR, Pham, TV, Olive, KP, Kazemier, G, van Laarhoven, HWM, Jimenez, CR, Bijlsma, MF & Giovannetti, E . Proteomic analysis of gemcitabine- resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment. Therapeutic advances in medical oncology 2019;11:: (Amsterdam UMC). 877. Le Rhun E, Devos P, Boulanger T, Smits M, Brandsma D, Ruda R, Furtner J, Hempel JM, Postma TJ, Roth P, Snijders TJ, Winkler F, Winklerhofer S, Castellano A, Hattingen E, Capellades J, Gorlia T, van den Bent M, Wen PY, Bendzus M, Weller M. The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility, and a revised proposal. Neuro Oncol 2019; 21:648-58 (Amsterdam UMC & NKI). 878. Lee A, Mavaddat N, Wilcox AN, Cunningham AP, Carver T, Hartley S, Babb d, V, Izquierdo A, Simard J, Schmidt MK, Walter FM, Chatterjee N, Garcia-Closas M, Tischkowitz M, Pharoah P, Easton DF, Antoniou AC. BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors. Genet Med 2019; 21:1708-18 (NKI). 879. Leeksma, AC, Taylor, J, Wu, B, Gardner, JR, He, J, Nahas, M, Gonen, M, Alemayehu, WG, te Raa, D, Walther, T, Hüllein, J, Dietrich, S, Claus, R, de Boer, F, de Heer, K, Dubois, J, Dampmann, M, Dürig, J, van Oers, MHJ, Geisler, CH, Eldering, E, Levine, RL, Miller, V, Mughal, T, Lamanna, N, Frattini, MG, Heaney, ML, Zelenetz, A, Zenz, T, Abdel-Wahab, O & Kater, AP . Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia. Leukemia 2019;33:2:390-402 (Amsterdam UMC). 880. Leemans C, van der Zwalm MCH, Brueckner L, Comoglio F, van Schaik T, Pagie L, van Arensbergen J, van Steensel B. Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs. Cell 2019; 177:852-64 (NKI). 881. Leenders, M, Kramer, G, Belghazi, K, Duvivier, K, van den Tol, P & Schreurs, H . Can We Identify or Exclude Extensive Axillary Nodal Involvement in Breast Cancer Patients Preoperatively?. Journal of oncology 2019 (Amsterdam UMC). 882. Leeneman, B, Franken, MG, Coupé, VMH, Hendriks, MP, Kruit, W, Plaisier, PW, van Ruth, S, Verstijnen, JAMC, Wouters, MWJM, Blommestein, HM & Uyl – de Groot, CA . Stage-specific disease recurrence and survival in localized and regionally advanced cutaneous melanoma. European Journal of Surgical Oncology 2019;45:5:825-831 (Amsterdam UMC & NKI). 883. Leerink JM, Feijen ELAM, Van der Pal HJH, Kok WEM, Mavinkurve-Groothuis AMC, Kapusta L, Pinto YM, Maas AHEM, Bellersen L, Teske AJ, Ronckers CM, Louwerens M, van Dalen EC, van Dulmen-den Broeder E, Batenburg L, van der Heiden-van der Loo M, van den Heuvel-Eibrink MM, van Leeuwen FE, de Vries ACH, Weijers G, de Korte CL, Loonen JJ, Neggers SJCM, Versluys ABB, Tissing WJE, Kremer LCM. Diagnostic tools for early detection of cardiac dysfunction in childhood cancer survivors: Methodological aspects of the Dutch late effects after childhood cancer (LATER) cardiology study. Am Heart J 2019; 219:89-98 (NKI). 884. Leerink, JM, Verkleij, SJ, Feijen, EAM, Mavinkurve-Groothuis, AMC, Pourier, MS, Ylänen, K, Tissing, WJE, Louwerens, M, van den Heuvel, MM, van Dulmen-den Broeder, E, de Vries, ACH, Ronckers, CM, van der Pal, HJH, Kapusta, L, Loonen, J, Bellersen, L, Pinto, YM, Kremer, LCM & Kok, WEM . Biomarkers to diagnose ventricular dysfunction in childhood cancer survivors: A systematic review. Heart 2019;105:3:210-216 (Amsterdam UMC). 885. Leijtens JWA, Koedam TWA, Borstlap WAA, Maas M, Doornebosch PG, Karsten TM, Derksen EJ, Stassen LPS, Rosman C, de Graaf EJR, Bremers AJA, Heemskerk J, Beets GL, Tuynman JB, Rademakers KLJ. Transanal Endoscopic Microsurgery with or without Completion Total Mesorectal Excision for T2 and T3 Rectal Carcinoma. Dig Surg 2019; 36:76-82 (NKI). 886. Lenaerts, L, Jatsenko, T, Amant, F & Robert Vermeesch, J . Noninvasive Prenatal Testing and Detection of Occult Maternal Malignancies. Clinical chemistry 2019;65:12:1484-1486 (Amsterdam UMC). 887. Lenaerts, L, van Calsteren, K, Che, H, Vermeesch, JR & Amant, F . Pregnant women with confirmed neoplasms should not have noninvasive prenatal testing. Prenatal diagnosis 2019;39:12:1162-1165 (Amsterdam UMC). 888. Lenaerts, L, Vandenberghe, P, Brison, N, Che, H, Neofytou, M, Verheecke, M, Leemans, L, Maggen, C, Dewaele, B, Dehaspe, L, Vanderschueren, S, Dierickx, D, Vandecaveye, V, Amant, F & Vermeesch, JR . Genomewide copy number alteration screening of circulating plasma DNA: potential for the detection of incipient tumors. Annals of oncology 2019;30:1:85-95 (Amsterdam UMC). 889. Lenos, KJ, Lodestijn, SC, Lyons, SK, Bijlsma, MF, Miedema, DM & Vermeulen, L . A marker- independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue. Nature protocols 2019;14:9:2648-2671 (Amsterdam UMC). 890. Lens SMA, Medema RH. Cytokinesis defects and cancer. Nat Rev Cancer 2019; 19:32-45 (NKI). 891. Lenting, K, Khurshed, M, Peeters, TH, van den Heuvel, CNAM, van Lith, SAM, de Bitter, T, Hendriks, W, Span, PN, Molenaar, RJ, Botman, D, Verrijp, K, Heerschap, A, Laan, MT, Kusters, B, van Ewijk, A, Huynen, MA, van Noorden, CJF & Leenders, WPJ . Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress. FASEB journal 2019;33:1:557- 571 (Amsterdam UMC). 892. Leonetti, A, Assaraf, YG, Veltsista, PD, El Hassouni, B, Tiseo, M & Giovannetti, E . MicroRNAs as a drug resistance mechanism to targeted therapies in EGFR-mutated NSCLC. Drug Resistance Updates 2019;42::1-11. (Amsterdam UMC). 893. Leonetti, A, Boyd, L, Giuliani, J, Giovannetti, E, Garajová, I & on Behalf of the EORTC PAMM Group . Light and shadow on innovative clinical trial designs. Expert Review of Clinical Pharmacology 2019;12:11:1033-1036 (Amsterdam UMC). 894. Leonetti, A, Facchinetti, F, Minari, R, Cortellini, A, Rolfo, CD, Giovannetti, E & Tiseo, M . Notch pathway in small-cell lung cancer: from preclinical evidence to therapeutic challenges. Cellular Oncology 2019;42:3:261-273 (Amsterdam UMC). 895. Leonetti, A, Sharma, S, Minari, R, Perego, P, Giovannetti, E & Tiseo, M . Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer. British Journal of Cancer 2019;121:9:725- 737 (Amsterdam UMC). 896. Leonetti, A, Wever, B, Mazzaschi, G, Assaraf, YG, Rolfo, C, Quaini, F, Tiseo, M & Giovannetti, E . Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer. Drug Resistance Updates 2019;46::100644 (Amsterdam UMC). 897. Li H, van der Leun AM, Yofe I, Lubling Y, Gelbard-Solodkin D, van Akkooi ACJ, van den Braber M, Rozeman EA, Haanen JBAG, Blank CU, Horlings HM, David E, Baran Y, Bercovich A, Lifshitz A, Schumacher TN, Tanay A, Amit I. Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma. Cell 2019; 176:775-89 (NKI). 898. Li Petri, G, Cascioferro, S, el Hassouni, B, Carbone, D, Parrino, B, Cirrincione, G, Peters, GJ, Diana, P & Giovannetti, E . Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives against Pancreatic Cancer Cells*. Anticancer Research 2019;39:7:3615-3620 (Amsterdam UMC). 899. Li W, Sparidans RW, Wang Y, Lebre MC, Beijnen JH, Schinkel AH. Oral coadministration of elacridar and ritonavir enhances brain accumulation and oral availability of the novel ALK/ROS1 inhibitor lorlatinib. Eur J Pharm Biopharm 2019; 136:120-30 (NKI). 900. Li, RJE, Hogervorst, TP, Achilli, S, Bruijns, SC, Arnoldus, T, Vivès, C, Wong, CC, Thépaut, M, Meeuwenoord, NJ, van den Elst, H, Overkleeft, HS, van der Marel, GA, Filippov, DV, van Vliet, SJ, Fieschi, F, Codée, JDC & van Kooyk, Y . Systematic Dual Targeting of Dendritic Cell C-Type Lectin Receptor DC-SIGN and TLR7 Using a Trifunctional Mannosylated Antigen. Frontiers in Medicinal Chemistry 2019;7:650: (Amsterdam UMC). 901. Licher S, van der Willik KD, Vinke EJ, Yilmaz P, Fani L, Schagen SB, Ikram MA, Ikram MK. Alzheimer's disease as a multistage process: an analysis from a population-based cohort study. Aging (Albany NY) 2019; 11:1163-76 (NKI). 902. Liegl G, Petersen MA, Groenvold M, Aaronson NK, Costantini A, Fayers PM, Holzner B, Johnson CD, Kemmler G, Tomaszewski KA, Waldmann A, Young TE, Rose M, Nolte S. Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core. Eur J Cancer 2019; 107:133-41 (NKI). 903. Lijftogt N, Vahl AC, van der Willik EM, Leijdekkers VJ, Wouters MWJM, Hamming JF, Dutch Society of Vascular Surgery tSCotDSAAatDIfCA. Towards Optimizing Risk Adjustment in the Dutch Surgical Aneurysm Audit (DSAA). Ann Vasc Surg 2019; 60:103-11 (NKI). 904. Lin S, Haque A, Raeman R, Guo L, He P, Denning TL, El-Rayes B, Moolenaar WH, Yun CC. Autotaxin determines colitis severity in mice and is secreted by B cells in the colon. FASEB J 2019; 33:3623-5 (NKI). 905. Lissenberg-Witte, BI, Bogaards, JA, Quint, WGV & Berkhof, J . Estimating the Human Papillomavirus Genotype Attribution in Screen-detected High-grade Cervical Lesions. Epidemiology (Cambridge, Mass.) 2019;30:4:590-596 (Amsterdam UMC). 906. Litière, S, Isaac, G, de Vries, EGE, Bogaerts, J, Chen, A, Dancey, J, Ford, R, Gwyther, S, Hoekstra, O, Huang, E, Lin, N, Liu, Y, Mandrekar, S, Schwartz, LH, Shankar, L, Therasse, P, Seymour, L & RECIST working group . RECIST 1.1 for Response Evaluation Apply Not Only to Chemotherapy-Treated Patients But Also to Targeted Cancer Agents: A Pooled Database Analysis. Journal of Clinical Oncology 2019;37:13:1102-1110 (Amsterdam UMC). 907. Liu D, Schilling B, Liu D, Sucker A, Livingstone E, Jerby-Amon L, Zimmer L, Gutzmer R, Satzger I, Loquai C, Grabbe S, Vokes N, Margolis CA, Conway J, He MX, Elmarakeby H, Dietlein F, Miao D, Tracy A, Gogas H, Goldinger SM, Utikal J, Blank CU, Rauschenberg R, von Bubnoff D, Krackhardt A, Weide B, Haferkamp S, Kiecker F, Izar B, Garraway L, Regev A, Flaherty K, Paschen A, Van Allen EM, Schadendorf D. Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma. Nat Med 2019; 25:1916-27 (NKI). 908. Liu J, Rozeman EA, O'Donnell JS, Allen S, Fanchi L, Smyth MJ, Blank CU, Teng MWL. Batf3(+) DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy. Oncoimmunology 2019; 8:e1546068 (NKI). 909. Liu NQ, de Wit E. A transient absence of SMC-mediated loops after mitosis. Nat Cell Biol 2019; 21:1303-4 (NKI). 910. Liu Y, van den Wildenberg WPM, de Graaf Y, Ames SL, Baldacchino A, Ragnhild B, Cadaveira F, Campanella S, Christiansen P, Claus ED, Colzato LS, Filbey FM, Foxe JJ, Garavan H, Hendershot CS, Hester R, Jester JM, Karoly HC, Kraplin A, Kreusch F, Landro NI, Littel M, Steins-Loeber S, London ED, Lopez-Caneda E, Lubman DI, Luijten M, Marczinski CA, Metrik J, Montgomery C, Papachristou H, Mi Park S, Paz AL, Petit G, Prisciandaro JJ, Quednow BB, Ray LA, Roberts CA, Roberts GMP, de Ruiter MB, Rupp CI, Steele VR, Sun D, Takagi M, Tapert SF, Holst RJV, Verdejo-Garcia A, Vonmoos M, Wojnar M, Yao Y, Yucel M, Zack M, Zucker RA, Huizenga HM, Wiers RW. Is (poly-) substance use associated with impaired inhibitory control? A mega-analysis controlling for confounders. Neurosci Biobehav Rev 2019; 105:288-304 (NKI). 911. Liu, DSK, Mato Prado, M, Giovannetti, E, Jiao, LR, Krell, J & Frampton, AE . Can circulating tumor and exosomal nucleic acids act as biomarkers for pancreatic ductal adenocarcinoma?. Expert review of molecular diagnostics 2019;19:7:553-558 (Amsterdam UMC). 912. Liu, P, Cao, W, Ma, B, Li, M, Chen, K, Sideras, K, Duitman, J-W, Sprengers, D, Khe Tran, TC, Ijzermans, JNM, Biermann, K, Verheij, J, Arnold Spek, C, Kwekkeboom, J, Pan, Q & Peppelenbosch, MP . Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma. Carcinogenesis 2019;40:1:155-163 (Amsterdam UMC). 913. Liu, Z, Yu, KJ, Coghill, AE, Brenner, N, Cao, S-M, Chen, C-J, Chen, Y, Doolan, DL, Hsu, W-L, Labo, N, Middeldorp, JM, Miley, W, Simon, J, Wang, C-P, Waterboer, T, Whitby, D, Xie, S-H, Ye, W & Hildesheim, A . Multilaboratory Assessment of Epstein-Barr Virus Serologic Assays: the Case for Standardization. Journal of Clinical Microbiology 2019;57:11: (Amsterdam UMC). 914. Ljungberg B, Albiges L, Abu-Ghanem Y, Bensalah K, Dabestani S, Montes SF, Giles RH, Hofmann F, Hora M, Kuczyk MA, Kuusk T, Lam TB, Marconi L, Merseburger AS, Powles T, Staehler M, Tahbaz R, Volpe A, Bex A. European Association of Urology Guidelines on Renal Cell Carcinoma: The 2019 Update. Eur Urol 2019; 75:799-810 (NKI). 915. Lodeizen, O, de Bruin, M, Eggener, S, Crouzet, SB, Ghai, S, Varkarakis, I, Katz, A, Dominguez-Escrig, JL, Pahernik, S, de Reijke, T & de la Rosette, J . Ablation energies for focal treatment of prostate cancer. World journal of urology 2019;37:3:409-418 (Amsterdam UMC). 916. Lodestijn, SC, Lenos, KJ, Miedema, DM, Bijlsma, MF & Vermeulen, L . Cancer stem cells: here, there, and everywhere. Molecular & cellular oncology 2019;6:1:e1540235 (Amsterdam UMC). 917. Loeff FC, Rijs K, van Egmond EHM, Zoutman WH, Qiao X, Kroes WGM, Veld SAJ, Griffioen M, Vermeer MH, Neefjes J, Falkenburg JHF, Halkes CJM, Jedema I. Loss of the GPI-anchor in B-lymphoblastic leukemia by epigenetic downregulation of PIGH expression. Am J Hematol 2019; 94:93-102 (NKI). 918. Loeffen, EAH, Knops, RRG, Boerhof, J, Feijen, EAML, Merks, JHM, Reedijk, AMJ, Lieverst, JA, Pieters, R, Boezen, HM, Kremer, LCM & Tissing, WJE . Treatment-related mortality in children with cancer: Prevalence and risk factors. European journal of cancer (Oxford, England 2019;121::113-122. (Amsterdam UMC). 919. Loeffen, EAH, Stinson, JN, Birnie, KA, van Dijk, M, Kulkarni, K, Rijsdijk, M, Font-Gonzalez, A, Dupuis, LL, van Dalen, EC, Mulder, RL, Campbell, F, Tissing, WJE, van de Wetering, MD & Gibson, F . Measurement properties of instruments to assess pain in children and adolescents with cancer: a systematic review protocol. Systematic reviews 2019;8:1:33 (Amsterdam UMC). 920. Lof, P, van de Vrie, R, Korse, CM, van Driel, WJ, van Gent, MDJM, Karlsen, MA, Amant, F & Lok, CAR . Pre-operative prediction of residual disease after interval cytoreduction for epithelial ovarian cancer using HE4. International journal of gynecological cancer 2019;29:8:1304-1310 (Amsterdam UMC & NKI). 921. Logtenberg MEW, Jansen JHM, Raaben M, Toebes M, Franke K, Brandsma AM, Matlung HL, Fauster A, Gomez-Eerland R, Bakker NAM, van der Schot S, Marijt KA, Verdoes M, Haanen JBAG, van den Berg JH, Neefjes J, van den Berg TK, Brummelkamp TR, Leusen JHW, Scheeren FA, Schumacher TN. Glutaminyl cyclase is an enzymatic modifier of the. Nat Med 2019; 25:612-9 (NKI). 922. Loh TP, Cervinski MA, Katayev A, Bietenbeck A, van Rossum H, Badrick T. Recommendations for laboratory informatics specifications needed for the application of patient-based real time quality control. Clin Chim Acta 2019; 495:625-9 (NKI). 923. Løhmann, DJA, Asdahl, PH, Abrahamsson, J, Ha, S-Y, Jónsson, ÓG, Kaspers, GJL, Koskenvuo, M, Lausen, B, de Moerloose, B, Palle, J, Zeller, B & Hasle, H . Use of granulocyte colony-stimulating factor and risk of relapse in pediatric patients treated for acute myeloid leukemia according to NOPHO-AML 2004 and DB AML-01. Pediatric Blood and Cancer 2019;66:6: (Amsterdam UMC). 924. Løhmann, DJA, Asdahl, PH, Abrahamsson, J, Ha, S-Y, Jónsson, ÓG, Kaspers, GJL, Koskenvuo, M, Lausen, B, de Moerloose, B, Palle, J, Zeller, B, Sung, L & Hasle, H . Associations between pretherapeutic body mass index, outcome, and cytogenetic abnormalities in pediatric acute myeloid leukemia. Cancer Medicine 2019;8:15:6634-6643 (Amsterdam UMC). 925. Lonning K, Putzky P, Sonke JJ, Reneman L, Caan MWA, Welling M. Recurrent inference machines for reconstructing heterogeneous MRI data. Med Image Anal 2019; 53:64-78 (NKI). 926. Lucas, M, Jansen, I, Savci-Heijink, CD, Meijer, SL, de Boer, OJ, van Leeuwen, TG, de Bruin, DM & Marquering, HA . Deep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies. Virchows Archiv 2019;475:1:77-83 (Amsterdam UMC). 927. Lucas, M, Liem, EIML, Savci-Heijink, CD, Freund, JE, Marquering, HA, van Leeuwen, TG & de Bruin, DM . Toward Automated In Vivo Bladder Tumor Stratification Using Confocal Laser Endomicroscopy. Journal of endourology / Endourological Society 2019;33:11:930-937 (Amsterdam UMC). 928. Lugli E, Kvistborg P, Galletti G. Cancer neoantigens targeted by adoptive T cell transfer: private no more. J Clin Invest 2019; 129:949-51 (NKI). 929. Luiten JD, Voogd AC, Tjan-Heijnen VCG, Wesseling J, Luiten EJT, Duijm LEM. Utility of diagnostic breast excision biopsies during two decades of screening mammography. Breast 2019; 46:157-62 (NKI). 930. Luong, NH, Alderliesten, T, Pieters, BR, Bel, A, Niatsetski, Y & Bosman, PAN . Fast and insightful bi- objective optimization for prostate cancer treatment planning with high-dose-rate brachytherapy. Applied Soft Computing Journal 2019;84:105681: (Amsterdam UMC). 931. Luteijn RD, van Diemen F, Blomen VA, Boer IGJ, Manikam Sadasivam S, van Kuppevelt TH, Drexler I, Brummelkamp TR, Lebbink RJ, Wiertz EJ. A genome-wide haploid genetic screen identifies heparan sulfate-associated genes and the macropinocytosis modulator TMED10 as factors supporting vaccinia virus infection. J Virol 2019; 93:e02160-18 (NKI). 932. Lutz, MP, Zalcberg, JR, Ducreux, M, Adenis, A, Allum, W, Aust, D, Carneiro, F, Grabsch, HI, Laurent- Puig, P, Lordick, F, Möhler, M, Mönig, S, Obermannova, R, Piessen, G, Riddell, A, Röcken, C, Roviello, F, Schneider, PM, Seewald, S, Smyth, E, van Cutsem, E, Verheij, M, Wagner, AD & Otto, F . The 4th St. Gallen EORTC Gastrointestinal Cancer Conference: Controversial issues in the multimodal primary treatment of gastric, junctional and oesophageal adenocarcinoma. European Journal of Cancer 2019;112::44044 (Amsterdam UMC & NKI). 933. Macagno, N, Vogels, R, Appay, R, Colin, C, Mokhtari, K, Küsters, B, Wesseling, P, Figarella-Branger, D, Flucke, U & Bouvier, C . Grading of meningeal solitary fibrous tumors/hemangiopericytomas: Analysis of the prognostic value of the Marseille Grading System in a cohort of 132 patients. Brain Pathology 2019;29:1:18-27 (Amsterdam UMC). 934. Machiels M, Voncken FEM, Jin P, van Dieren JM, Bartels-Rutten A, Alderliesten T, Aleman BMP, van Hooft JE, Hulshof MCCM. A novel liquid fiducial marker in esophageal cancer image-guided radiotherapy: technical feasibility and visibility on imaging. Pract Radiat Oncol 2019; 9:e506-e515 (Amsterdam UMC & NKI). 935. Machiels, M, van Montfoort, ML, Thuijs, NB, van Berge Henegouwen, MI, Alderliesten, T, Meijer, SL, van Hooft, JE & Hulshof, MCCM . Microscopic tumor spread beyond (echo)endoscopically determined tumor borders in esophageal cancer. Radiation oncology (London, England) 2019;14:1:219 (Amsterdam UMC). 936. Machiels, ML, Jin, P, van Hooft, JE, Gurney-Champion, OJ, Jelvehgaran, P, Geijsen, ED, Jeene, PM, Willemijn Kolff, M, Oppedijk, V, Rasch, CRN, van Herk, MB, Alderliesten, T & Hulshof, MCCM . Reduced inter-observer and intra-observer delineation variation in esophageal cancer radiotherapy by use of fiducial markers. Acta oncologica (Stockholm, Sweden) 2019 (Amsterdam UMC). 937. Maes, A, Maes, K, de Raeve, H, de Smedt, E, Vlummens, P, Szablewski, V, Devin, J, Faict, S, de Veirman, K, Menu, E, Offner, F, Spaargaren, M, Moreaux, JR, Vanderkerken, K, van Valckenborgh, E & de Bruyne, E . The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma. British journal of cancer 2019;120:12:1137-1146 (Amsterdam UMC). 938. Maggen, C, van Gerwen, M, van Calsteren, K, Vandenbroucke, T & Amant, F . Management of cancer during pregnancy and current evidence of obstetric, neonatal and pediatric outcome: A review article. International journal of gynecological cancer 2019;29:2:404-416 (Amsterdam UMC & NKI). 939. Mair, R, Mouliere, F, Smith, CG, Chandrananda, D, Gale, D, Marass, F, Tsui, DWY, Massie, CE, Wright, AJ, Watts, C, Rosenfeld, N & Brindle, KM . Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models. Cancer Research 2019;79:1:220-230 (Amsterdam UMC). 940. Manders, P, Vos, JR, de Voer, RM, van Hest, LP, Sijmons, R, Hoge, CV, Terpstra, FG, Spaander, MC, Mesker, WE, Dekker, E & Hoogerbrugge, N . Parelsnoer institute biobank hereditary colorectal cancer: A joint infrastructure for patient data and biomaterial on hereditary colorectal cancer in the Netherlands. Open Journal of Bioresources 2019;6:1.: (Amsterdam UMC). 941. Mannaerts, CK, Kajtazovic, A, Lodeizen, OAP, Gayet, M, Engelbrecht, MRW, Jager, GJ, Wijkstra, H, de Reijke, TM & Beerlage, HP . The added value of systematic biopsy in men with suspicion of prostate cancer undergoing multiparametric MRI-targeted biopsy. Urologic oncology 2019;37:5:298 (Amsterdam UMC). 942. Mannaerts, CK, Wildeboer, RR, Remmers, S, van Kollenburg, RAA, Kajtazovic, A, Hagemann, J, Postema, AW, van Sloun, RJG, J Roobol, M, Tilki, D, Mischi, M, Wijkstra, H & Salomon, G . Multiparametric Ultrasound for Prostate Cancer Detection and Localization: Correlation of B-mode, Shear Wave Elastography and Contrast Enhanced Ultrasound with Radical Prostatectomy Specimens. Journal of urology 2019;202:6:1166-1173 (Amsterdam UMC). 943. Mannu GS, Groen EJ, Wang Z, Schaapveld M, Lips EH, Chung M, Joore I, van Leeuwen FE, Teertstra HJ, Winter-Warnars GAO, Darby SC, Wesseling J. Reliability of preoperative breast biopsies showing ductal carcinoma in situ and implications for non-operative treatment: a cohort study. Breast Cancer Res Treat 2019; 178:409-18 (NKI). 944. Manso JA, Gomez-Hernandez M, Carabias A, onso-Garcia N, Garcia-Rubio I, Kreft M, Sonnenberg A, de Pereda JM. Integrin alpha6beta4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure 2019; 27:952-64 (NKI). 945. Mansour, MB, Crone, MR, van Weert, HC, Chavannes, NH & van Asselt, KM . Smoking cessation advice after cervical screening: a qualitative interview study of acceptability in Dutch primary care. British journal of general practice 2019;69:678:e15-e23 (Amsterdam UMC). 946. Mantel F, Sweeney RA, Klement RJ, Hawkins MA, Belderbos J, Ahmed M, Toussaint A, Polat B, Flentje M, Guckenberger M. Risk factors for vertebral compression fracture after spine stereotactic body radiation therapy: Long-term results of a prospective phase 2 study. Radiother Oncol 2019; 141:62-6 (NKI). 947. Marcelo, F, Supekar, N, Corzana, F, van der Horst, JC, Vuist, IM, Live, D, Boons, G-JPH, Smith, DF & van Vliet, SJ . Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands. Journal of Biological Chemistry 2019 (Amsterdam UMC). 948. Marconi L, Bensalah K, Bex A. Re: Paul C.M.S. Verhagen, Egbert R. Boeve. The European Association of Urology Guideline on Renal Cell Carcinoma (RCC) is Not Concise in its Recommendation to Perform Partial Nephrectomy in T1b RCC. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2019.01.020. Eur Urol 2019; 76:e12-e13 [Letter] (NKI). 949. Marcuello M, Vymetalkova V, Neves RPL, Duran-Sanchon S, Vedeld H, Tham E, van Dalum G, Flugen G, Garcia-Barberan V, Fijneman RJ, Castells A, Vodicka P, Lind GE, Stoecklein NH, Heitzer E, Gironella M. Circulating biomarkers for early detection and clinical management of colorectal cancer. Mol Aspects Med 2019; 69:107-22 (NKI). 950. Mardenborough YSN, Nitsenko K, Laffeber C, Duboc C, Sahin E, Quessada-Vial A, Winterwerp HHK, Sixma TK, Kanaar R, Friedhoff P, Strick TR, Lebbink JHG. The unstructured linker arms of MutL enable GATC site incision beyond roadblocks during initiation of DNA mismatch repair. Nucleic Acids Res 2019; 47:11667-80 (NKI). 951. Maree, SC, Luong, NH, Kooreman, ES, van Wieringen, N, Bel, A, Hinnen, KA, Westerveld, H, Pieters, BR, Bosman, PAN & Alderliesten, T . Evaluation of bi-objective treatment planning for high-dose-rate prostate brachytherapy—A retrospective observer study. Brachytherapy 2019;18:3:396-403 (Amsterdam UMC). 952. Marinelli, O, Annibali, D, Aguzzi, C, Tuyaerts, S, Amant, F, Morelli, MB, Santoni, G, Amantini, C, Maggi, F & Nabissi, M . The Controversial Role of PD-1 and Its Ligands in Gynecological Malignancies. Frontiers in oncology 2019;9:1073.: (Amsterdam UMC). 953. Markus HS, Harshfield EL, Compter A, Kuker W, Kappelle LJ, Clifton A, van der Worp HB, Rothwell P, Algra A. Stenting for symptomatic vertebral artery stenosis: a preplanned pooled individual patient data analysis. Lancet Neurol 2019; 18:666-73 (NKI). 954. Marquardt S, Kirstein MM, Bruning R, Zeile M, Ferrucci PF, Prevoo W, Radeleff B, Trillaud H, Tselikas L, Vicente E, Wiggermann P, Manns MP, Vogel A, Wacker FK. Percutaneous hepatic perfusion (chemosaturation) with melphalan in patients with intrahepatic cholangiocarcinoma: European multicentre study on safety, short-term effects and survival. Eur Radiol 2019; 29:1882-92 (NKI). 955. Marra, E, Siegenbeek van Heukelom, ML, Leeman, A, Waterboer, T, Meijer, CJLM, Snijders, PJF, King, AJ, Cairo, I, van Eeden, A, Brokking, W, van der Weele, P, Quint, W, Prins, JM, de Vries, HJC & Schim van der Loeff, MF . Virological and serological predictors of anal high-grade squamous intraepithelial lesions among human immunodeficiency virus-positive men who have sex with men. Clinical Infectious Diseases 2019;68:8:1376-1387 (Amsterdam UMC). 956. Martens, RM, Noij, DP, Ali, M, Koopman, T, Marcus, JT, Vergeer, MR, de Vet, H, de Jong, MC, Leemans, CR, Hoekstra, OS, de Bree, R, de Graaf, P, Boellaard, R & Castelijns, JA . Functional imaging early during (chemo)radiotherapy for response prediction in head and neck squamous cell carcinoma; a systematic review. Oral Oncology 2019;88::75-83 (Amsterdam UMC). 957. Martens, RM, Noij, DP, Koopman, T, Zwezerijnen, B, Heymans, M, de Jong, MC, Hoekstra, OS, Vergeer, MR, de Bree, R, Leemans, CR, de Graaf, P, Boellaard, R & Castelijns, JA . Predictive value of quantitative diffusion-weighted imaging and 18-F-FDG-PET in head and neck squamous cell carcinoma treated by (chemo)radiotherapy. European Journal of Radiology 2019;113::39-50 (Amsterdam UMC). 958. Martin E, Coert JH, Flucke UE, Slooff WM, Ho VKY, van der Graaf WT, van DT, van de Sande MAJ, van Houdt WJ, Grunhagen DJ, Verhoef C. A nationwide cohort study on treatment and survival in patients with malignant peripheral nerve sheath tumours. Eur J Cancer 2019; 124:77-87 (NKI). 959. Martin E, Dullaart MJ, van de Sande MAJ, van Houdt WJ, Schellekens PPA, Coert JH. Resuscitating extremities after soft tissue sarcoma resections: Are functional reconstructions an overlooked option in limb salvage? A systematic review. Eur J Surg Oncol 2019; 45:1762-9 (NKI). 960. Martinez-Chavez A, Rosing H, Hillebrand M, Tibben M, Schinkel AH, Beijnen JH. Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2019; 411:5331-45 (NKI). 961. Martinez-Chavez A, van Hoppe S, Rosing H, Lebre MC, Tibben M, Beijnen JH, Schinkel AH. P- glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability. Mol Pharm 2019; 16:3842-52 (NKI). 962. Martínez-Moreno, NE, Sahgal, A, de Salles, A, Hayashi, M, Levivier, M, Ma, L, Paddick, I, Régis, J, Ryu, S, Slotman, BJ & Martínez-Álvarez, R . Stereotactic radiosurgery for tremor: Systematic review. Journal of Neurosurgery 2019;130:2:589-600 (Amsterdam UMC). 963. Martín-Garcia, D, Navarro, A, Valdés-Mas, R, Clot, G, Gutiérrez-Abril, J, Prieto, M, Ribera-Cortada, I, Woroniecka, R, Rymkiewicz, G, Bens, S, de Leval, L, Rosenwald, A, Ferry, JA, Hsi, ED, Fu, K, Delabie, J, Weisenburger, D, de Jong, D, Climent, F, O. CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D12 mantle cell lymphoma. Blood 2019;133:9:940-951 (Amsterdam UMC). 964. Martini A, Gandaglia G, Karnes RJ, Zaffuto E, Bianchi M, Gontero P, Chlosta P, Gratzke C, Graefen M, Tilki D, Cucchiara V, Mirone V, Kneitz B, Sanchez SR, van der Poel H, Tombal B, Spahn M, Joniau TS, Montorsi F, Briganti A. Defining the Most Informative Intermediate Clinical Endpoints for Predicting Overall Survival in Patients Treated with Radical Prostatectomy for High-risk Prostate Cancer. Eur Urol Oncol 2019; 2:456-63 (NKI). 965. Masroor S, van Dongen MGJ, Alvarez-Jimenez R, Burggraaf K, Peletier LA, Peletier MA. Mathematical modeling of the glucagon challenge test. J Pharmacokinet Pharmacodyn 2019; 46:553-64 (NKI). 966. Matthijs de Wit, L, van Uden-Kraan, CF, Lissenberg-Witte, BI, Melissant, HC, Fleuren, MAH, Cuijpers, P & Verdonck-de Leeuw, IM . Adoption and implementation of a web-based self-management application “Oncokompas” in routine cancer care: a national pilot study. Supportive Care in Cancer 2019;27:8:2911-2920 (Amsterdam UMC). 967. Matulonis UA, Shapira-Frommer R, Santin AD, Lisyanskaya AS, Pignata S, Vergote I, Raspagliesi F, Sonke GS, Birrer M, Provencher DM, Sehouli J, Colombo N, Gonzalez-Martin A, Oaknin A, Ottevanger PB, Rudaitis V, Katchar K, Wu H, Keefe S, Ruman J, Ledermann JA. Antitumor Activity and Safety of Pembrolizumab in Patients with Advanced Recurrent Ovarian Cancer: Results from the Phase 2 KEYNOTE-100 Study. Ann Oncol 2019; 30:1080-7 (NKI). 968. Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L, Lee A, Tyrer JP, Chen TH, Wang Q, Bolla MK, Yang X, Adank MA, Ahearn T, Aittomaki K, Allen J, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Auer PL, Auvinen P, Barrdahl M, Beane Freeman LE, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Bogdanova NV, Bojesen SE, Bonanni B, Borresen- Dale AL, Brauch H, Bremer M, Brenner H, Brentnall A, Brock IW, Brooks-Wilson A, Brucker SY, Bruning T, Burwinkel B, Campa D, Carter BD, Castelao JE, Chanock SJ, Chlebowski R, Christiansen H, Clarke CL, Collee JM, Cordina-Duverger E, Cornelissen S, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dork T, Dos-Santos-Silva I, Dumont M, Durcan L, Dwek M, Eccles DM, Ekici AB, Eliassen AH, Ellberg C, Engel C, Eriksson M, Evans DG, Fasching PA, Figueroa J, Fletcher O, Flyger H, Forsti A, Fritschi L, Gabrielson M, Gago-Dominguez M, Gapstur SM, Garcia-Saenz JA, Gaudet MM, Georgoulias V, Giles GG, Gilyazova IR, Glendon G, Goldberg MS, Goldgar DE, Gonzalez-Neira A, Grenaker Alnaes GI, Grip M, Gronwald J, Grundy A, Guenel P, Haeberle L, Hahnen E, Haiman CA, Hakansson N, Hamann U, Hankinson SE, Harkness EF, Hart SN, He W, Hein A, Heyworth J, Hillemanns P, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Howell A, Huang G, Humphreys K, Hunter DJ, Jakimovska M, Jakubowska A, Janni W, John EM, Johnson N, Jones ME, Jukkola-Vuorinen A, Jung A, Kaaks R, Kaczmarek K, Kataja V, Keeman R, Kerin MJ, Khusnutdinova E, Kiiski JI, Knight JA, Ko YD, Kosma VM, Koutros S, Kristensen VN, Kruger U, Kuhl T, Lambrechts D, Le Marchand L, Lee E, Lejbkowicz F, Lilyquist J, Lindblom A, Lindstrom S, Lissowska J, Lo WY, Loibl S, Long J, Lubinski J, Lux MP, MacInnis RJ, Maishman T, Makalic E, Maleva K, I, Mannermaa A, Manoukian S, Margolin S, Martens JWM, Martinez ME, Mavroudis D, McLean C, Meindl A, Menon U, Middha P, Miller N, Moreno F, Mulligan AM, Mulot C, Munoz-Garzon VM, Neuhausen SL, Nevanlinna H, Neven P, Newman WG, Nielsen SF, Nordestgaard BG, Norman A, Offit K, Olson JE, Olsson H, Orr N, Pankratz VS, Park-Simon TW, Perez JIA, Perez-Barrios C, Peterlongo P, Peto J, Pinchev M, Plaseska-Karanfilska D, Polley EC, Prentice R, Presneau N, Prokofyeva D, Purrington K, Pylkas K, Rack B, Radice P, Rau-Murthy R, Rennert G, Rennert HS, Rhenius V, Robson M, Romero A, Ruddy KJ, Ruebner M, Saloustros E, Sandler DP, Sawyer EJ, Schmidt DF, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Schumacher F, Schurmann P, Schwentner L, Scott C, Scott RJ, Seynaeve C, Shah M, Sherman ME, Shrubsole MJ, Shu XO, Slager S, Smeets A, Sohn C, Soucy P, Southey MC, Spinelli JJ, Stegmaier C, Stone J, Swerdlow AJ, Tamimi RM, Tapper WJ, Taylor JA, Terry MB, Thone K, Tollenaar RAEM, Tomlinson I, Truong T, Tzardi M, Ulmer HU, Untch M, Vachon CM, van Veen EM, Vijai J, Weinberg CR, Wendt C, Whittemore AS, Wildiers H, Willett W, Winqvist R, Wolk A, Yang XR, Yannoukakos D, Zhang Y, Zheng W, Ziogas A. Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. Am J Hum Genet 2019; 104:21-34 (NKI). 969. Mazrooei P, Kron KJ, Zhu Y, Zhou S, Grillo G, Mehdi T, Ahmed M, Severson TM, Guilhamon P, Armstrong NS, Huang V, Yamaguchi TN, Fraser M, van der Kwast T, Boutros PC, He HH, Bergman AM, Bristow RG, Zwart W, Lupien M. Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors. Cancer Cell 2019; 36:674-89(NKI). 970. Mbui J, Olobo J, Omollo R, Solomos A, Kip A, Kirigi G, Sagaki P, Kimutai R, Were L, Omollo T, Egondi T, Wasunna M, Alvar J, Dorlo T, Alves F. Pharmacokinetics, safety and efficacy of an allometric miltefosine regimen for the treatment of visceral leishmaniasis in Eastern African children: an open- label, phase-II clinical trial. Clin Infect Dis 2019; 68:1530-8 (NKI). 971. McCulloch MM, Lee C, Rosen BS, Kamp JD, Lockhart CM, Lee JY, Polan DF, Hawkin PG, Anderson CJR, Heukelom J, Sonke JJ, Fuller CD, Balter JM, Ten Haken RK, Eisbruch A, Brock KK. Predictive models to determine clinically relevant deviations in delivered dose for head and neck cancer. Pract Radiat Oncol 2019; 9:e422-e431 (NKI). 972. Mcdonald, F, Senan, S, Faivre-Finn, C & Hatton, M . Curative Radiotherapy for Non-small Cell Lung Cancer. Clinical Oncology 2019;31:10:678-680 (Amsterdam UMC). 973. McNair H, Buijs M. Image guided radiotherapy moving towards real time adaptive radiotherapy; global positioning system for radiotherapy? Tech Innov Patient Support Radiat Oncol 2019; 12:1-2 [Editorial] . (NKI). 974. Meel, MH, Kaspers, GJL & Hulleman, E . Preclinical therapeutic targets in diffuse midline glioma. Drug Resistance Updates 2019;44::15-25. (Amsterdam UMC). 975. Meershoek P, van den Berg NS, Brouwer OR, Teertstra HJ, Lange CAH, Valdes Olmos RA, van der Hiel B, Balm AJM, Klop WMC, van Leeuwen FWB. Three dimensional tumor-margin demarcation using the hybrid tracer indocyanine green-(99m)Tc-nanocolloid, a proof of concept study in tongue cancer patients scheduled for sentinel node biopsy. J Nucl Med 2019; 60:764-9 (NKI). 976. Meershoek P, van Oosterom MN, Simon H, Mengus L, Maurer T, van Leeuwen PJ, Wit EMK, van der Poel HG, van Leeuwen FWB. Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first- in-human translation. Eur J Nucl Med Mol Imaging 2019; 46:49-53 (NKI). 977. Mehanna, H, Robinson, M, Hartley, A, Kong, A, Foran, B, Fulton-Lieuw, T, Dalby, M, Mistry, P, Sen, M, O. Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial. Lancet 2019;393:10166:51-60 (Amsterdam UMC). 978. Meijer, D, van Moorselaar, RJA, Vis, AN & Bijnsdorp, IV . Prostate cancer development is not affected by statin use in patients with elevated psa levels. Cancers (Basel) 2019;11:7: (Amsterdam UMC). 979. Meijer, LL, Puik, JR, le Large, TYS, Heger, M, Dijk, F, Funel, N, Wurdinger, T, Garajová, I, van Grieken, NCT, van de Wiel, MA, Giovannetti, E & Kazemier, G . Unravelling the diagnostic dilemma: A microrna panel of circulating MIR-16 and MIR-877 as a diagnostic classifier for distal bile duct tumors. Cancers (Basel) 2019;11:8: (Amsterdam UMC). 980. Meijer, LL, Zwart, ES, Brandt, BW, Mebius, R, Deng, D, Giovannetti, E, Zaura, E & Kazemier, G . Tumor microbiome: Pancreatic cancer and duodenal fluids contain multitudes, ...but do they contradict themselves?. Critical Reviews in Oncology / Hematology 2019;144:: (Amsterdam UMC). 981. Meijerink, MR, Puijk, RS & van den Tol, PMP . COLLISION Trial Seeks to Answer Time-Honored Question: “Thermal Ablation or Surgery for Colorectal Liver Metastases?”. CardioVascular and Interventional Radiology 2019;42:8:1059-1061 (Amsterdam UMC). 982. Melissant, HC, van Uden-Kraan, CF, Lissenberg-Witte, BI & Verdonck-de Leeuw, IM . Body changes after cancer: female cancer patients’ perceived social support and their perspective on care. Supportive Care in Cancer 2019;27:11:4299-4306 (Amsterdam UMC). 983. Menden, MP, Wang, D, Mason, MJ, Szalai, B, Bulusu, KC, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, AstraZeneca-Sanger Drug Combination DREAM Consortium, Jang, IS, Ghazoui, Z, Ahsen, ME, Vogel, R, Neto, EC, Norman, T, Tang, EKY, Garnett, MJ, Veroli, GYD, Fawell, S, Stolovitzky, G, Guinney, J, Dry, JR & Saez-Rodriguez, J . Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications 2019;10:1: (Amsterdam UMC). 984. Mendeville, M, Roemer, MGM, van den Hout, MFCM, Los-de Vries, GT, Bladergroen, R, Stathi, P, Hijmering, NJ, Rosenwald, A, Ylstra, B & de Jong, D . Aggressive genomic features in clinically indolent primary HHV8-negative effusion-based lymphoma. Blood 2019;133:4:377-380 (Amsterdam UMC). 985. Menezes GLG, Mann RM, Meeuwis C, Bisschops B, Veltman J, Lavin PT, van de Vijver MJ, Pijnappel RM. Optoacoustic imaging of the breast: correlation with histopathology and histopathologic biomarkers. Eur Radiol 2019; 29:6728-40 (NKI). 986. Menko FH, Ter Stege JA, van der Kolk LE, Jeanson KN, Schats W, Moha DA, Bleiker EMA. The uptake of presymptomatic genetic testing in hereditary breast-ovarian cancer and Lynch syndrome: a systematic review of the literature and implications for clinical practice. Fam Cancer 2019; 18:127-35 (NKI). 987. Menzer C, Menzies AM, Carlino MS, Reijers I, Groen EJ, Eigentler T, de Groot JWB, van der Veldt AAM, Johnson DB, Meiss F, Schlaak M, Schilling B, Westgeest HM, Gutzmer R, Pfohler C, Meier F, Zimmer L, Suijkerbuijk KPM, Haalck T, Thoms KM, Herbschleb K, Leichsenring J, Menzer A, Kopp- Schneider A, Long GV, Kefford R, Enk A, Blank CU, Hassel JC. Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations. J Clin Oncol 2019; 37:3142-51 (NKI). 988. Mercieca, S, Belderbos, J, Gilson, D, Dickson, J, Pan, S & van Herk, M . Implementing the Royal College of Radiologists' Radiotherapy Target Volume Definition and Peer Review Guidelines: More Still To Do?. Clinical oncology (Royal College of Radiologists (Great Britain)) 2019;31:10:706-710 (Amsterdam UMC & NKI). 989. Mercieca, S, Belderbos, JSA, van Baardwijk, A, Delorme, S & van Herk, M . The impact of training and professional collaboration on the interobserver variation of lung cancer delineations: a multi- institutional study. Acta oncologica (Stockholm, Sweden) 2019;58:2:200-208 (Amsterdam UMC & NKI). 990. Merino D, Weber TS, Serrano A, Vaillant F, Liu K, Pal B, Di Stefano L, Schreuder J, Lin D, Chen Y, sselin-Labat ML, Schumacher TN, Cameron D, Smyth GK, Papenfuss AT, Lindeman GJ, Visvader JE, Naik SH. Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer. Nat Commun 2019; 10:766 (NKI). 991. Merkul, E, Sijbrandi, NJ, Muns, JA, Aydin, I, Adamzek, K, Houthoff, H-J, Nijmeijer, B & van Dongen, GAMS . First platinum(II)-based metal-organic linker technology (Lx®) for a plug-and-play development of antibody-drug conjugates (ADCs). Expert Opinion on Drug Delivery 2019;16:8:783- 793 (Amsterdam UMC). 992. Mertens LS, Behrendt MA, Mehta AM, Stokkel L, de Jong J, Boot H, Horenblas S, van der Heijden MS, Moonen LM, Aalbers AGJ, Meinhardt W, van Rhijn BWG. Long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with peritoneal metastases of urachal cancer. Eur J Surg Oncol 2019; 45:1740-4 (NKI). 993. Metselaar, DS, Meel, MH, Benedict, B, Waranecki, P, Koster, J, Kaspers, GJL & Hulleman, E . Celastrol- induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin. EBioMedicine 2019;50::81-92. (Amsterdam UMC & NKI). 994. Meulepas JM, Ronckers CM, Smets AMJB, Nievelstein RAJ, Gradowska P, Lee C, Jahnen A, van Straten M, de Wit MY, Zonnenberg B, Klein WM, Merks JH, Visser O, van Leeuwen FE, Hauptmann M. Response to Wollschläger, Blettner, and Pokora. J Natl Cancer Inst 2019; 111:102-3 [Letter] (NKI). 995. Meulepas, JM, Ronckers, CCM, Smets, AMJB, Nievelstein, RAJ, Gradowska, P, Lee, C, Jahnen, A, van Straten, M, de Wit, M-CY, Zonnenberg, B, Klein, WM, Merks, JH, Visser, O, van Leeuwen, FE & Hauptmann, M . Radiation exposure from pediatric CT scans and subsequent cancer risk in the Netherlands. Journal of the National Cancer Institute 2019;111:3:256-263 (Amsterdam UMC & NKI). 996. Mezzadra R, de Bruijn M, Jae LT, Gomez-Eerland R, Duursma A, Scheeren FA, Brummelkamp TR, Schumacher TN. SLFN11 can sensitize tumor cells towards IFN-gamma-mediated T cell killing. PLoS One 2019; 14:e0212053 (NKI). 997. Michel, G, Mulder, RL, van der Pal, HJH, Skinner, R, Bárdi, E, Brown, MC, Vetsch, J, Frey, E, Windsor, R, Kremer, LCM & Levitt, G . Evidence-based recommendations for the organization of long-term follow-up care for childhood and adolescent cancer survivors: a report from the PanCareSurFup Guidelines Working Group. Journal of cancer survivorship 2019;13:5:759-772 (Amsterdam UMC). 998. Michels S, Massuti B, Schildhaus HU, Franklin J, Sebastian M, Felip E, Grohe C, Rodriguez-Abreu D, Abdulla DSY, Bischoff H, Brandts C, Carcereny E, Corral J, Dingemans AC, Pereira E, Fassunke J, Fischer RN, Gardizi M, Heukamp L, Insa A, Kron A, Menon R, Persigehl T, Reck M, Riedel R, Rothschild SI, Scheel AH, Scheffler M, Schmalz P, Smit EF, Limburg M, Provencio M, Karachaliou N, Merkelbach- Bruse S, Hellmich M, Nogova L, Buttner R, Rosell R, Wolf J. Safety and efficacy of crizotinib in patients with advanced or metastatic ROS1-rearranged lung cancer (EUCROSS): A European phase 2 clinical trial. J Thorac Oncol 2019; 14:1266-76 (NKI). 999. Michielin O, van Akkooi A, Ascierto P, Dummer R, Keilholz U. Cutaneous melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-updagger. Ann Oncol 2019; 30:1884-901 (NKI). 1000. Mieras, A, Becker-Commissaris, A, Pasman, HRW, Dingemans, AMMC, Kok, EV, Cornelissen, R, Jacobs, W, van den Berg, JW, Welling, A, Bogaarts, BAHA, Pronk, L & Onwuteaka-Philipsen, BD . Chemotherapy and Tyrosine Kinase Inhibitors in the last month of life in patients with metastatic lung cancer. European Journal of Cancer Care 2019 (Amsterdam UMC). 1001. Mieras, A, Pasman, HRW, Onwuteaka-Philipsen, BD, Dingemans, A-MMC, Kok, EV, Cornelissen, R, Jacobs, W, van den Berg, J-W, Welling, A, Bogaarts, BAHA, Pronk, L & Becker-Commissaris, A . Is In- Hospital Mortality Higher in Patients With Metastatic Lung Cancer Who Received Treatment in the Last Month of Life? A Retrospective Cohort Study. Journal of Pain and Symptom Management 2019;58:5:805-811 (Amsterdam UMC). 1002. Mierzynska, J, Piccinin, C, Pe, M, Martinelli, F, Gotay, C, Coens, C, Mauer, M, Eggermont, A, Groenvold, M, Bjordal, K, Reijneveld, J, Velikova, G & Bottomley, A . Prognostic value of patient- reported outcomes from international randomised clinical trials on cancer. Lancet Oncology 2019;20:12:e685-e698 (Amsterdam UMC). 1003. Mijnheer B. EPIDs and QA of advanced treatments. J Phys Conf Ser 2019; 1305:01261 (9 pp) (NKI). 1004. Milne K, Sun J, Zaal EA, Mowat J, Celie PHN, Fish A, Berkers CR, Forlani G, Loayza-Puch F, Jamieson C, Agami R. A fragment-like approach to PYCR1 inhibition. Bioorg Med Chem Lett 2019; 29:2626-31 (NKI). 1005. Min LA, Vogel WV, Lahaye MJ, Maas M, Donswijk ML, Vegt E, Kusters M, Zijlmans HJ, Jozwiak K, Roberti S, Beets-Tan RGH, Lambregts DMJ. Integrated versus separate reading of F-18 FDG-PET/CT and MRI for abdominal malignancies - effect on staging outcomes and diagnostic confidence. Eur Radiol 2019; 29:6900-10 (NKI). 1006. Mina, R, Bringhen, S, Wildes, TM, Zweegman, S & Rosko, AE . Approach to the Older Adult With Multiple Myeloma. American Society of Clinical Oncology educational book 2019;39::500-518. (Amsterdam UMC). 1007. Minnema, MC, Nasserinejad, K, Hazenberg, B, Hegenbart, U, Vlummens, P, Ypma, PF, Kröger, N, Wu, KL, Kersten, MJ, Schaafsma, MR, Croockewit, S, de Waal, E, Zweegman, S, Tick, L, Broijl, A, Koene, H, Bos, G, Sonneveld, P & Schönland, S . Bortezomib-based induction followed by stem cell transplantation in light chain amyloidosis: Results of the multicenter HOVON 104 trial. Haematologica 2019;104:11:2274-2282 (Amsterdam UMC). 1008. Miranda, RN, Medeiros, LJ, Ferrufino-Schmidt, MC, Keech, JA, Brody, GS, de Jong, D, Dogan, A & Clemens, MW . Pioneers of Breast Implant-Associated Anaplastic Large Cell Lymphoma. Plastic and reconstructive surgery 2019;143:3S:7S-14S (Amsterdam UMC). 1009. Mirosevic, S, Thewes, B, van Herpen, C, Kaanders, J, Merkx, T, Humphris, G, Baatenburg de Jong, RJ, Langendijk, JA, Leemans, CR, Terhaard, CHJ, Verdonck-de Leeuw, IM, Takes, R, Prins, J & the NET- QUBIC Consortium . Prevalence and clinical and psychological correlates of high fear of cancer recurrence in patients newly diagnosed with head and neck cancer. Head and Neck 2019;41:9:3187- 3200 (Amsterdam UMC). 1010. Mittempergher L, Delahaye LJ, Witteveen A, Spangler JB, Hassenmahomed F, Mee S, Mahmoudi S, Chen J, Bao S, Snel MH, Leidelmeijer S, Besseling N, Lucas AB, Pabon-Pena C, Linn SC, Dreezen C, Wehkamp D, Chan BY, Bernards R, van 't Veer LJ, Glas AM. MammaPrint and BluePrint Molecular Diagnostics using targeted RNA Next-Generation Sequencing technology. J Mol Diagn 2019; 21:808- 23 (NKI). 1011. Moek, KL, Waaijer, SJH, Kok, IC, Suurs, FV, Brouwers, AH, Menke-van der Houven van Oordt, CW, Wind, TT, Gietema, JA, Schröder, CP, Mahesh, SVK, Jorritsma-Smit, A, Lub-de Hooge, MN, Fehrmann, RSN, de Groot, DJA & de Vries, EGE . 89Zr-labeled bispecific T-cell engager AMG 211 PET shows AMG 211 accumulation in CD3-rich tissues and clear, heterogeneous tumor uptake. Clinical Cancer Research 2019;25:12:3517-3527 (Amsterdam UMC). 1012. Moelans CB, de Ligt J, van der Groep P, Prins P, Besselink N, Hoogstraat M, Ter Hoeve N, Lacle M, Kornegoor R, van der Pol C, de Leng W, Barbe E, van der Vegt B, Martens J, Bult P, Smits VT, Koudijs M, Nijman I, Voest E, Selenica P, Weigelt B, Reis-Filho J, van der Wall E, Cuppen E, van Diest PJ . The molecular genetic make-up of male breast cancer. Endocr Relat Cancer 2019; 26:779-94 (NKI). 1013. Mokadem, I, Dijksterhuis, WPM, van Putten, M, Heuthorst, L, de Vos-Geelen, JM, Haj Mohammad, N, Nieuwenhuijzen, GAP, van Laarhoven, HWM & Verhoeven, RHA . Recurrence after preoperative chemotherapy and surgery for gastric adenocarcinoma: a multicenter study. Gastric cancer 2019;22:6:1263-1273 (Amsterdam UMC). 1014. Molenaar, RJ, van Hattum, JW, Brummelhuis, IS, Oddens, JR, Savci-Heijink, CD, Boevé, ER, van der Meer, SA, Witjes, JF, Pollak, MN, de Reijke, TM & Wilmink, JW . Study protocol of a phase II clinical trial of oral metformin for the intravesical treatment of non-muscle invasive bladder cancer. BMC cancer 2019;19:1:1133 (Amsterdam UMC). 1015. Montemurro F, Ellis P, Anton A, Wuerstlein R, Delaloge S, Bonneterre J, Quenel-Tueux N, Linn SC, Irahara N, Donica M, Lindegger N, Barrios CH. Safety of trastuzumab emtansine (T-DM1) in patients with HER2-positive advanced breast cancer: Primary results from the KAMILLA study cohort 1. Eur J Cancer 2019; 109:92-102 (NKI). 1016. Montero-Luis A, Aristei C, Meattini I, Arenas M, Boersma L, Bourgier C, Coles C, Cutuli B, Falcinelli L, Kaidar-Person O, Leonardi MC, Offersen B, Marazzi F, Rivera S, Tagliaferri L, Tombolini V, Vidali C, Valentini V, Poortmans P. The Assisi Think Tank Meeting Survey of post-mastectomy radiation therapy in ductal carcinoma in situ: Suggestions for routine practice. Crit Rev Oncol Hematol 2019; 138:207-13 (NKI). 1017. Moolenaar WH, Balla T. Editorial overview: Signaling dynamics moving to the nanoscale. Curr Opin Cell Biol 2019; 57:iii-ivi [Editorial] (NKI). 1018. Moosavi, F, Giovannetti, E, Saso, L & Firuzi, O . HGF/MET pathway aberrations as diagnostic, prognostic, and predictive biomarkers in human cancers. Critical Reviews in Clinical Laboratory Sciences 2019;56:8:533-566 (Amsterdam UMC). 1019. Moreau, P, Attal, M, Hulin, C, Arnulf, B, Belhadj, K, Benboubker, L, Béné, MC, Broijl, A, Caillon, HL, Caillot, D, Corre, J, Delforge, M, Dejoie, T, Doyen, C, Facon, T, Sonntag, CC, Fontan, J, Garderet, L, Jie, K-S, Karlin, L, Kuhnowski, F, Lambert, JR, Leleu, X, Lenain, P, Macro, M, Mathiot, C, Orsini-Piocelle, F, Perrot, A, Stoppa, A-M, van de Donk, NWCJ, Wuilleme, S, Zweegman, S, Kolb, B, Touzeau, C, Roussel, M, Tiab, M, Marolleau, J-P, Meuleman, N, Vekemans, M-C, Westerman, M, Klein, SK, Levin, M-D, Fermand, JP, Escoffre-Barbe, M, Eveillard, J-R, Garidi, R, Ahmadi, T, Zhuang, S, Chiu, C, Pei, L, de Boer, C, Smith, E, Deraedt, W, Kampfenkel, T, Schecter, J, Vermeulen, J, Avet-Loiseau, H & Sonneveld, P . Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study. Lancet 2019;394:10192:29-38 (Amsterdam UMC). 1020. Moreau, P, Rajkumar, SV, Mateos, M-V, Gay, F, Skacel, T, Schjesvold, F, Chng, WJ, Hajek, R, Zweegman, S, Min, C-K, Dash, AB, Pluta, A, Iida, S, Labotka, R, Teng, Z, Spencer, A, Kaiser, M, Weisel, KC, Dimopoulos, M, Beksac, M, Suryanarayan, K, Morgan, G, Maisnar, V & Goldschmidt, H . Double- Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity. Biology of Blood and Marrow Transplantation 2019;25:1:19-25 (Amsterdam UMC). 1021. Morkholt AS, Trabjerg MS, Oklinski MKE, Bolther L, Kroese LJ, Pritchard CEJ, Huijbers IJ, Nieland JDV. CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis. Sci Rep 2019; 9:13299 (NKI). 1022. Morris L, Squire R, Sznajder B, Van Tinteren H, Godzinski J, Powis M. Optimal neoadjuvant chemotherapy duration in Wilms tumour with intravascular thrombus: A literature review and evidence from SIOP WT 2001 trial. Pediatr Blood Cancer 2019; 66:e27930 (NKI). 1023. Morsink, LM, Walter, RB & Ossenkoppele, GJ . Prognostic and therapeutic role of CLEC12A in acute myeloid leukemia. Blood Reviews 2019;34::26-33. (Amsterdam UMC). 1024. Moshaver, B, Wouters, RF, Kelder, A, Ossenkoppele, GJ, Westra, GAH, Kwidama, Z, Rutten, AR, Kaspers, GJL, Zweegman, S, Cloos, J & Schuurhuis, GJ . Relationship between CD34/CD38 and side population (SP) defined leukemia stem cell compartments in acute myeloid leukemia. Leukemia Research 2019;81::27-34. (Amsterdam UMC). 1025. Motzer RJ, Penkov K, Haanen J, Rini B, Albiges L, Campbell MT, Venugopal B, Kollmannsberger C, Negrier S, Uemura M, Lee JL, Vasiliev A, Miller WH, Jr. , Gurney H, Schmidinger M, Larkin J, Atkins MB, Bedke J, Alekseev B, Wang J, Mariani M, Robbins PB, Chudnovsky A, Fowst C, Hariharan S, Huang B, di Pietro A, Choueiri TK. Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma(NKI). 1026. Mourragui, S, Loog, M, Van De Wiel, MA, Reinders, MJT & Wessels, LFA . PRECISE. Bioinformatics 2019;35:14: (Amsterdam UMC & NKI). 1027. Mulder, RL, Bresters, D, van den Hof, M, Koot, BGP, Castellino, SM, Loke, YKK, Post, PN, Postma, A, Sznyi, LSP, Levitt, GA, Bardi, E, Skinner, R & van Dalen, EC . Hepatic late adverse effects after antineoplastic treatment for childhood cancer. Cochrane database of systematic reviews (Online) 2019;4:4: (Amsterdam UMC). 1028. Mulero-Sanchez A, Pogacar Z, Vecchione L. Importance of genetic screens in precision oncology. ESMO Open 2019; 4:e000505 (10 pp) (NKI). 1029. Muller DMJ, Robe PAJT, Eijgelaar RS, Witte MG, Visser M, de Munck JC, Broekman MLD, Seute T, Hendrikse J, Noske DP, Vandertop WP, Barkhof F, Kouwenhoven MCM, Mandonnet E, Berger MS, De Witt Hamer PC. Comparing Glioblastoma Surgery Decisions Between Teams Using Brain Maps of Tumor Locations, Biopsies, and Resections. JCO Clin Cancer Inform 2019; 3:1-12 (NKI). 1030. Muller M, Baas P. I love my dog. Lung Cancer 2019; 135:228-9 [Editorial] (NKI). 1031. Müller, DMJ, Robe, PAJT, Eijgelaar, RS, Witte, MG, Visser, M, de Munck, JC, Broekman, MLD, Seute, T, Hendrikse, J, Noske, DP, Vandertop, WP, Barkhof, F, Kouwenhoven, MCM, Mandonnet, E, Berger, MS & Hamer, PCDW . Comparing glioblastoma surgery decisions between teams using brain maps of tumor locations, biopsies, and resections. JCO clinical cancer informatics 2019;3:3:44166 (Amsterdam UMC). 1032. Müller, HL, Merks, JHM, Geoerger, B, Grill, J, Hargrave, D, Glade Bender, J, Gururangan, S, Navid, F, Johnston, M, Bachir, J, Elze, MC & Fürst-Recktenwald, S . Integrated analysis of long-term growth and bone development in pediatric and adolescent patients receiving bevacizumab. Pediatric blood & cancer 2019;66:2: (Amsterdam UMC). 1033. Muller, J, Duray, E, Lejeune, M, Dubois, S, Plougonven, E, Léonard, A, Storti, P, Giuliani, N, Cohen- Solal, M, Hempel, U, Thijssen, VL, Beguin, Y, Heusschen, R & Caers, J . Loss of stromal galectin-1 enhances multiple myeloma development: Emphasis on a role in osteoclasts. Cancers (Basel) 2019;11:2: (Amsterdam UMC). 1034. Mungroop, TH, Geerts, BF, Veelo, DP, Pawlik, TM, Bonnet, A, Lesurtel, M, Reyntjens, KM, Noji, T, Liu, C, Jonas, E, Wu, CL, de Santibañes, E, Abu Hilal, M, Hollmann, MW, Besselink, MG & van Gulik, TM . Fluid and pain management in liver surgery (MILESTONE): A worldwide study among surgeons and anesthesiologists. Surgery 2019;165:2:337-344 (Amsterdam UMC). 1035. Mungroop, TH, van Rijssen, LB, van Klaveren, D, Smits, FJ, van Woerden, V, Linnemann, RJ, de Pastena, M, Klompmaker, S, Marchegiani, G, Ecker, BL, van Dieren, S, Bonsing, B, Busch, OR, van Dam, RM, Erdmann, J, van Eijck, CH, Gerhards, MF, van Goor, H, van der Harst, E, de Hingh, IH, de Jong, KP, Kazemier, G, Luyer, M, Shamali, A, Barbaro, S, Armstrong, T, Takhar, A, Hamady, Z, Klaase, J, Lips, DJ, Molenaar, IQ, Nieuwenhuijs, VB, Rupert, C, van Santvoort, HC, Scheepers, JJ, van der Schelling, GP, Bassi, C, Vollmer, CM, Steyerberg, EW, Abu Hilal, M, Groot Koerkamp, B, Besselink, MG & Dutch Pancreatic Cancer Group . Alternative Fistula Risk Score for Pancreatoduodenectomy (a- FRS). Annals of Surgery 2019;269:5:937-943 (Amsterdam UMC). 1036. Munier, FL, Beck-Popovic, M, Chantada, GL, Cobrinik, D, Kivelä, TT, Lohmann, D, Maeder, P, Moll, AC, Carcaboso, AM, Moulin, A, Schaiquevich, P, Bergin, C, Dyson, PJ, Houghton, S, Puccinelli, F, Vial, Y, Gaillard, M-C & Stathopoulos, C . Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace. “Alive, with good vision and no comorbidity”. Progress in Retinal and Eye Research 2019;73:: (Amsterdam UMC). 1037. Nadiarnykh, O, Davidoiu, V, Gräfe, MGO, Bosscha, M, Moll, AC & de Boer, JF . Phase-based OCT angiography in diagnostic imaging of pediatric retinoblastoma patients: Abnormal blood vessels in post-treatment regression patterns. Biomedical Optics Express 2019;10:5:2213-2226 (Amsterdam UMC). 1038. Nagel R, Avelar AT, Aben N, Proost N, van de Ven M, Van der Vliet J, Cozijnsen M, de Vries H, Wessels LFA, Berns A. Inhibition of the replication stress response is a synthetic vulnerability in SCLC that acts synergistically in combination with cisplatin. Mol Cancer Ther 2019; 18:762-70 (NKI). 1039. Naik, J, Hau, CM, Bloemendaal, LT, Mok, KS, Hajji, N, Wehman, AM, Meisner, S, Muncan, V, Paauw, NJ, de Vries, HE, Nieuwland, R, Paulusma, CC & Bosma, PJ . The P4-ATPase ATP9A is a novel determinant of exosome release. PLoS ONE 2019;14:4: (Amsterdam UMC). 1040. Naik, J, Themeli, M, de Jong-Korlaar, R, Ruiter, RWJ, Poddighe, PJ, Yuan, H, de Bruijn, JD, Ossenkoppele, GJ, Zweegman, S, Smit, L, Mutis, T, Martens, ACM, van de Donk, NWCJ & Groen, RWJ . CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia. Haematologica 2019;104:3:e100-e103 (Amsterdam UMC). 1041. Nasir I, Fernandez L, Vieira P, Pares O, Santiago I, Castillo-Martin M, Domingos H, Cunha JF, Carvalho C, Heald RJ, Beets GL, Parvaiz A, Figueiredo N. Salvage surgery for local regrowths in Watch & Wait - Are we harming our patients by deferring the surgery? Eur J Surg Oncol 2019; 45:1559-66 . (NKI). 1042. Nathan P, Ascierto PA, Haanen J, Espinosa E, Demidov L, Garbe C, Guida M, Lorigan P, Chiarion-Sileni V, Gogas H, Maio M, Fierro MT, Hoeller C, Terheyden P, Gutzmer R, Guren TK, Bafaloukos D, Rutkowski P, Plummer R, Waterston A, Kaatz M, Mandala M, Marquez-Rodas I, Munoz-Couselo E, Dummer R, Grigoryeva E, Young TC, Schadendorf D. Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open- label, phase II study (CheckMate 172). Eur J Cancer 2019; 119:168-78 (NKI). 1043. Navran A, Heemsbergen W, Janssen T, Hamming-Vrieze O, Jonker M, Zuur C, Verheij M, Remeijer P, Sonke JJ, van den Brekel M, Al Mamgani A. The impact of margin reduction on outcome and toxicity in head and neck cancer patients treated with image-guided volumetric modulated arc therapy (VMAT). Radiother Oncol 2019; 130:25-31 (NKI). 1044. Necchi A, Mariani L, Lo Vullo S, Yu EY, Woods ME, Wong YN, Harshman LC, Alva A, Sternberg CN, Bamias A, Grivas P, Koshkin VS, Roghmann F, Dobruch J, Eigl BJ, Nappi L, Milowsky MI, Niegisch G, Pal SK, De Giorgi U, Recine F, Vaishampayan U, Berthold DD, Bowles DW, Baniel J, Theodore C, Ladoire S, Srinivas S, Agarwal N, Crabb S, Sridhar S, Golshayan AR, Ohlmann C, Xylinas E, Powles T, Rosenberg JE, Bellmunt J, van Rhijn B, Galsky MD, Hendricksen K. Lack of Effectiveness of Postchemotherapy Lymphadenectomy in Bladder Cancer Patients with Clinical Evidence of Metastatic Pelvic or Retroperitoneal Lymph Nodes Only: A Propensity Score-based Analysis. Eur Urol Focus 2019; 5:242-9 (NKI). 1045. Nederlof, I, de Bortoli, D, Bareche, Y, Nguyen, B, de Maaker, M, Hooijer, GKJ, Buisseret, L, Kok, M, Smid, M, van den Eynden, GGGM, Brinkman, AB, Hudecek, J, Koster, J, Sotiriou, C, Larsimont, D, Martens, JWM, van de Vijver, MJ, Horlings, HM, Salgado, R, Biganzoli, E & Desmedt, C . Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer. Breast cancer research 2019;21:1: (Amsterdam UMC & NKI). 1046. Neefjes, ECW, Van Der Vorst, MJDL, Boddaert, MSA, Verdegaal, BATT, Beeker, A, Teunissen, SCC, Beekman, ATF, Zuurmond, WWA, Berkhof, J & Verheul, HMW . Accuracy of the Delirium Observational Screening Scale (DOS) as a screening tool for delirium in patients with advanced cancer. BMC Cancer 2019;19:1: (Amsterdam UMC). 1047. Negenborn, VL, Smit, JM, Dikmans, REG, Winters, HAH, Twisk, JWR, Ruhé, PQ, Mureau, MAM, Tuinder, S, Eltahir, Y, Posch, NAS, van Steveninck-Barends, JM, van der Hulst, RRWJ, Ritt, MJPF, Bouman, MB & Mullender, MG . Short-term cost-effectiveness of one-stage implant-based breast reconstruction with an acellular dermal matrix versus two-stage expander-implant reconstruction from a multicentre randomized clinical trial. British Journal of Surgery 2019;106:5:586-595 (Amsterdam UMC). 1048. Negenborn, VL, van Turnhout, AAWM, Fuchs, SP, Lisabeth-Broné, K, Vermulst, N, Vogten, JM, Twisk, JWR, Vriens-Nieuwenhuis, EJC, Mullender, MG & van der Sluis, WB . A retrospective study on surgical outcomes and patient satisfaction of EGIS® ADM in one-stage implant-based breast reconstruction. Journal of Plastic, Reconstructive and Aesthetic Surgery 2019;72:1:137-171 (Amsterdam UMC). 1049. Neijenhuijs KI, Holtmaat K, Aaronson NK, Holzner B, Terwee CB, Cuijpers P, Verdonck-de Leeuw I. The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties. J Sex Med 2019; 6:1078-91 (NKI). 1050. Neijenhuijs KI, Hooghiemstra N, Holtmaat K, Aaronson NK, Groenvold M, Holzner B, Terwee CB, Cuijpers P, Verdonck-de Leeuw I. The Female Sexual Function Index (FSFI)-A Systematic Review of Measurement Properties. J Sex Med 2019; 16:640-60 (NKI). 1051. Neijenhuijs, KI, van der Hout, A, Veldhuijzen, E, Scholten-Peeters, GGM, van Uden-Kraan, CF, Cuijpers, P & Verdonck-de Leeuw, IM . Translation of the eHealth Impact Questionnaire for a Population of Dutch Electronic Health Users: Validation Study. Journal of Medical Internet Research 2019;21:8: (Amsterdam UMC). 1052. Nejati B, Lin CC, Aaronson NK, Cheng ASK, Browall M, Lin CY, Brostrom A, Pakpour AH. Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma. Psychooncology 2019; 28:1490-7 (NKI). 1053. Nerad E, Delli Pizzi A, Lambregts DMJ, Maas M, Wadhwani S, Bakers FCH, van den Bosch HCM, Beets- Tan RGH, Lahaye MJ. The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor. PLoS One 2019; 14:e0211830 (NKI). 1054. Nersisyan, L, Nikoghosyan, M, Arakelyan, A, Francioli, LC, Menelaou, A, Pulit, SL, Elbers, CC, Kloosterman, WP, van Setten, J, Nijman, IJ, Renkens, I, de Bakker, PIW, van Dijk, F, Neerincx, PBT, Deelen, P, Kanterakis, A, Dijkstra, M, Byelas, H, van der Velde, KJ, Platteel, M, Swertz, MA, Wijmenga, C, Palamara, PF, Pe’er, I, Ye, K, Ye, K, Lameijer, E-W, Moed, MH, Beekman, M, de Craen, AJM, Suchiman, HED, Slagboom, PE, Guryev, V, Abdellaoui, A, Jan Hottenga, J, Kattenberg, M, Willemsen, G, Boomsma, DI, van Leeuwen, EM, Karssen, LC, Amin, N, Rivadeneira, F, Isaacs, A, Hofman, A, Uitterlinden, AG, van Duijn, CM, van Oven, M, van Schaik, BDC, van Leeuwen, EM, van Schaik, BDC & The Genome of the Netherlands consortium . WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene. Scientific reports 2019;9:1: (Amsterdam UMC). 1055. Ngai, LL, ter Veer, E, van den Boorn, HCG, van Herk, EH, van Kleef, JJ, van Oijen, MGH & van Laarhoven, HWM . TOXview: a novel graphical presentation of cancer treatment toxicity profiles. Acta oncologica (Stockholm, Sweden) 2019;58:8:1138-1148 (Amsterdam UMC). 1056. Nguyen B, Venet D, Lambertini M, Desmedt C, Salgado R, Horlings HM, Rothe F, Sotiriou C. Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer. Breast Cancer Res 2019; 21:25 (NKI). 1057. Nguyen, MH, Bol, N, van Weert, JCM, Loos, EF, Tytgat, KMAJ, Geijsen, D, Drenth, E, Janse, M & Smets, EMA . Optimising eHealth tools for older patients: Collaborative redesign of a hospital website. European journal of cancer care 2019;28:1: (Amsterdam UMC). 1058. Nguyen, MH, Smets, EM, Bol, N, Loos, EF, van Laarhoven, HW, Geijsen, D, van Berge Henegouwen, MI, Tytgat, KM & van Weert, JC . Tailored Web-Based Information for Younger and Older Patients with Cancer: Randomized Controlled Trial of a Preparatory Educational Intervention on Patient Outcomes. Journal of medical Internet research 2019;21:10:e14407 (Amsterdam UMC). 1059. Nguyen, MH, Smets, EMA, Bol, N, Bronner, MB, Tytgat, KMAJ, Loos, EF & van Weert, JCM . Fear and forget: how anxiety impacts information recall in newly diagnosed cancer patients visiting a fast- track clinic. Acta oncologica (Stockholm, Sweden) 2019;58:2:182-188 (Amsterdam UMC). 1060. Nieuwenhuis J, Brummelkamp TR. The Tubulin Detyrosination Cycle: Function and Enzymes. Trends Cell Biol 2019; 29:80-92 (NKI). 1061. Nijdam, A, Dekker, N, Aleman, BMP, van ’t Veer, MB, Daniels, LA, van der Maazen, RW, Janus, CPM, de Weijer, RJ, Zijlstra, JM, Stedema, FG, Ta, BD, Posthuma, EFM, Manenschijn, A, Dielwart, MFH, Bilgin, YM, van den Heuvel, MJ, Boersma, RS, van Leeuwen, FE, Raemaekers, JMM & the BETER consortium . Setting up a national infrastructure for survivorship care after treatment for Hodgkin lymphoma. British Journal of Haematology 2019;186:4:e103-e108 (Amsterdam UMC & NKI). 1062. Nijkamp J, Kuhlmann KFD, Ivashchenko O, Pouw B, Hoetjes N, Lindenberg MA, Aalbers AGJ, Beets GL, Van Coevorden F, KoK N, Ruers TJM. Prospective study on image-guided navigation surgery for pelvic malignancies. J Surg Oncol 2019; 119:510-7 (NKI). 1063. Nilsson, RJA, Balaj, L, Hulleman, E, Van Rijn, S, Pegtel, DM, Walraven, M, Widmark, A, Gerritsen, WR, Verheul, HM, Vandertop, WP, Noske, DP, Skog, J & Wurdinger, T . Supplemental data for Blood platelets contain tumor-derived RNA biomarkers. Journal of Applied Physics 2019;5:Xxx:17-20 (Amsterdam UMC). 1064. Nolte S, Liegl G, Petersen MA, Aaronson NK, Costantini A, Fayers PM, Groenvold M, Holzner B, Johnson CD, Kemmler G, Tomaszewski KA, Waldmann A, Young TE, Rose M. General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States. Eur J Cancer 2019; 107:153-63 (NKI). 1065. Noordhuis, P, Laan, AC, van de Born, K, Honeywell, RJ & Peters, GJ . Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines. International Journal of Molecular Sciences 2019;20:15: (Amsterdam UMC). 1066. Noordman, BJ, Verdam, MGE, Onstenk, B, Heisterkamp, J, Jansen, WJBM, Martijnse, IS, Lagarde, SM, Wijnhoven, BPL, Acosta, CMM, van der Gaast, A, Sprangers, MAG & van Lanschot, JJB . Quality of Life During and After Completion of Neoadjuvant Chemoradiotherapy for Esophageal and Junctional Cancer. Annals of surgical oncology 2019;26:13:4765-4772 (Amsterdam UMC). 1067. Nosaki K, Saka H, Hosomi Y, Baas P, de Castro GJ, Reck M, Wu YL, Brahmer JR, Felip E, Sawada T, Noguchi K, Han SR, Piperdi B, Kush DA, Lopes G. Safety and efficacy of pembrolizumab monotherapy in elderly patients with PD-L1-positive advanced non-small-cell lung cancer: Pooled analysis from the KEYNOTE-010, KEYNOTE-024, and KEYNOTE-042 studies. Lung Cancer 2019; 135:188-95 (NKI). 1068. Nowak-Sliwinska, P, van Beijnum, JR, Huijbers, EJM, Gasull, PC, Mans, L, Bex, A & Griffioen, AW . Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatment. British Journal of Cancer 2019;120:2:218-228 (Amsterdam UMC & NKI). 1069. Nowee ME, Voncken FEM, Kotte ANTJ, Goense L, van Rossum PSN, van Lier ALHM, Heijmink SW, Aleman BMP, Nijkamp J, Meijer GJ, Lips IM. Gross tumour delineation on computed tomography and positron emission tomography-computed tomography in oesophageal cancer: A nationwide study. Clin Transl Radiat Oncol 2019; 14:33-9 (NKI). 1070. O. Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre- Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate. Proteomics. Clinical applications 2019;13:1800159: (Amsterdam UMC). 1071. O'Donnell JS, Hoefsmit EP, Smyth MJ, Blank CU, Teng MWL. The promise of neoadjuvant immunotherapy and surgery for cancer treatment. Clin Cancer Res 2019; 25:5743-51 (NKI). 1072. Oei, AL, Korangath, P, Mulka, K, Helenius, M, Coulter, JB, Stewart, J, Velarde, E, Crezee, J, Simons, B, Stalpers, LJA, Kok, HP, Gabrielson, K, Franken, NAP & Ivkov, R . Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer. International journal of hyperthermia 2019;36::47-63 (Amsterdam UMC). 1073. Ogura A, Konishi T, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, Lee IK, Lee HX, Uehara K, Lee P, Putter H, van de Velde CJH, Beets GL, Rutten HJT, Kusters M. Neoadjuvant (Chemo)radiotherapy With Total Mesorectal Excision Only Is Not Sufficient to Prevent Lateral Local Recurrence in Enlarged Nodes: Results of the Multicenter Lateral Node Study of Patients With Low cT3/4 Rectal Cancer. J Clin Oncol 2019; 37:33-43 (NKI). 1074. Ogura, A, Konishi, T, Beets, GL, Cunningham, C, Garcia-Aguilar, J, Iversen, H, Toda, S, Lee, IK, Lee, HX, Uehara, K, Lee, P, Putter, H, van de Velde, CJH, Rutten, HJT, Tuynman, JB & Kusters, M . Lateral Nodal Features on Restaging Magnetic Resonance Imaging Associated with Lateral Local Recurrence in Low Rectal Cancer after Neoadjuvant Chemoradiotherapy or Radiotherapy. JAMA Surgery 2019;154:9: (Amsterdam UMC & NKI). 1075. Olaciregui-Ruiz I, Rozendaal R, Mijnheer B, Mans A. Site-specific alert criteria to detect patient related errors with 3D EPID transit dosimetry. Med Phys 2019; 46:45-55 (NKI). 1076. Olaciregui-Ruiz I, Vivas-Maiques B, Kaas J, Perik T, Wittkamper F, Mijnheer B, Mans A. Transit and non-transit 3D EPID dosimetry versus detector arrays for patient specific QA. J Appl Clin Med Phys 2019; 20:79-90 (NKI). 1077. Olde Heuvel J, de Wit-van der Veen BJ, Vyas KN, Tuch DS, Grootendorst MR, Stokkel MPM, Slump CH. Performance evaluation of Cerenkov luminescence imaging: a comparison of (68)Ga with (18)F. EJNMMI Phys 2019; 6:17 (NKI). 1078. Olson, R, Senan, S, Harrow, S, Gaede, S, Louie, A, Haasbeek, C, Mulroy, L, Lock, M, Rodrigues, G, Yaremko, B, Schellenberg, D, Ahmad, B, Griffioen, G, Senthi, S, Swaminath, A, Kopek, N, Liu, M, Moore, K, Currie, S, Bauman, G, Warner, A & Palma, D . Quality of Life Outcomes After Stereotactic Ablative Radiation Therapy (SABR) Versus Standard of Care Treatments in the Oligometastatic Setting. International Journal of Radiation Oncology Biology Physics 2019;105:5:943-947 (Amsterdam UMC). 1079. Olthof, PB, Miyasaka, M, Koerkamp, BG, Wiggers, JK, Jarnagin, WR, Noji, T, Hirano, S & van Gulik, TM . A comparison of treatment and outcomes of perihilar cholangiocarcinoma between Eastern and Western centers. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:3:345-351 (Amsterdam UMC). 1080. on behalf of the DCOG-LATER Study Group, Streefkerk, N, Heins, MJ, Teepen, JC, Feijen, EAM, Bresters, D, van Dulmen-den Broeder, E, van der Heiden-van der Loo, M, van den Heuvel-Eibrink, MM, van Leeuwen, FE, Loonen, JJ, van der Pal, HJH, Ronckers, CCM, Versluys, AB, Tissing, WJE, Korevaar, JC & Kremer, LCM . The involvement of primary care physicians in care for childhood cancer survivors. Pediatric blood & cancer 2019 (Amsterdam UMC). 1081. on behalf of the Dutch Benign Liver Tumour Group, van Rosmalen, BV, Klompenhouwer, AJ, de Graeff, JJ, Haring, MPD, de Meijer, VE, Rifai, L, Dokmak, S, Rawashdeh, A, Abu Hilal, M, de Jong, MC, Dejong, CHC, Doukas, M, de Man, RA, IJzermans, JNM, van Delden, OM, Verheij, J & van Gulik, TM . Safety and efficacy of transarterial embolization of hepatocellular adenomas. British journal of surgery 2019;106:10:1362-1371 (Amsterdam UMC). 1082. on behalf of the Dutch Pancreatic Cancer Group, Scholten, L, Stoop, TF, del Chiaro, M, Busch, OR, van Eijck, C, Molenaar, IQ, de Vries, JH & Besselink, MG . Systematic review of functional outcome and quality of life after total pancreatectomy. British journal of surgery 2019;106:13:1735-1746 (Amsterdam UMC). 1083. on behalf of the Dutch Snapshot Research Group, Amelung, FJ, Borstlap, WAA, Consten, ECJ, Veld, JV, van Halsema, EE, Bemelman, WA, Siersema, PD, ter Borg, F, van Hooft, JE, Tanis, PJ, Algera, H, Algie, GD, Andeweg, CS, Argillander, T, Arron, MNNJ, Arts, K, Aufenacker, THJ, Bakker, IS, van Basten Batenburg, M, Bastiaansen, AJNM, Beets, GL, van den Berg, A, van de Beukel, B, Blom, RLGM, Blomberg, B, Boerma, EG, den Boer, FC, Bouvy, ND, Bouwman, JE, Boye, NDA, Brandt, ARM, Brandsma, HT, Breijer, A, van den Broek, W, Bröker, MEE, Burbach, JPM, Bruns, ERJ, Burghgraef, TA, Crolla, RMPH, Marres, CCM, Sierink, JC, Swank, HA, Tuynman, JB, van Westreenen, HL, Bruns, ERJ, Marres, CCM, Sierink, JC, Swank, HA, Tuynman, JB, van Westreenen, HL, van der Zaag, ES, Zimmerman, D & Zwols, T . Propensity score-matched analysis of oncological outcome between stent as bridge to surgery and emergency resection in patients with malignant left-sided colonic obstruction. British journal of surgery 2019;106:8:1075-1086 (Amsterdam UMC). 1084. on behalf of the Dutch Snapshot Research Group, Furnée, EJB, Aukema, TS, Oosterling, SJ, Borstlap, WAA, Bemelman, WA & Tanis, PJ . Influence of Conversion and Anastomotic Leakage on Survival in Rectal Cancer Surgery; Retrospective Cross-sectional Study. Journal of gastrointestinal surgery 2019;23:10:2007-2018 (Amsterdam UMC). 1085. on behalf of the International TaTME Registry Collaborative, Roodbeen, SX, de Lacy, FB, van Dieren, S, Penna, M, Ris, F, Moran, B, Tekkis, P, Bemelman, WA & Hompes, R . Predictive Factors and Risk Model for Positive Circumferential Resection Margin Rate after Transanal Total Mesorectal Excision in 2653 Patients with Rectal Cancer. Annals of surgery 2019;270:5:884–891 (Amsterdam UMC). 1086. on behalf of the Pain in Children with Cancer Guideline Development Panel, Loeffen, EAH, Kremer, LCM, van de Wetering, MD, Mulder, RL, Font-Gonzalez, A, Dupuis, LL, Campbell, F & Tissing, WJE . Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline. Pediatric blood & cancer 2019;66:6: (Amsterdam UMC). 1087. On behalf of the Writing Committee of the International Network on Cancer, Infertility and Pregnancy (INCIP) on this particular manuscript, Kocián, P, de Haan, J, Cardonick, EH, Uzan, C, Lok, CAR, Fruscio, R, Halaska, MJ & Amant, F . Management and outcome of colorectal cancer during pregnancy: report of 41 cases. Acta chirurgica Belgica 2019;119:3:166-175 (Amsterdam UMC). 1088. Ooft SN, Weeber F, Dijkstra KK, McLean CM, Kaing S, van Werkhoven E, Schipper L, Hoes L, Vis DJ, van de Haar J, Prevoo W, Snaebjornsson P, van der Velden D, Klein M, Chalabi M, Boot H, van Leerdam M, Bloemendal HJ, Beerepoot LV, Wessels L, Cuppen E, Clevers H, Voest EE. Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients. Sci Transl Med 2019; 11:eaay2574 (9 pp) (NKI). 1089. Oort, Q, Taphoorn, MJB, Sikkes, SAM, Uitdehaag, BMJ, Reijneveld, JC & Dirven, L . Evaluation of the content coverage of questionnaires containing basic and instrumental activities of daily living (ADL) used in adult patients with brain tumors. Journal of Neuro-Oncology 2019;143:1:41275 (Amsterdam UMC). 1090. Oosterveld-Vlug, MG, Custers, B, Hofstede, J, Donker, GA, Rijken, PM, Korevaar, JC & Francke, AL . What are essential elements of high-quality palliative care at home? An interview study among patients and relatives faced with advanced cancer. BMC Palliative Care 2019;18:1: (Amsterdam UMC). 1091. Oostindie, SC, Van Der Horst, HJ, Lindorfer, MA, Cook, EM, Tupitza, JC, Zent, CS, Burack, R, VanDerMeid, KR, Strumane, K, Chamuleau, MED, Mutis, T, De Jong, RN, Schuurman, J, Breij, ECW, Beurskens, FJ, Parren, PWHI & Taylor, RP . CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering. Haematologica 2019;104:9:1841-1852 (Amsterdam UMC). 1092. Opstal-van Winden AWJ, de Haan HG, Hauptmann M, Schmidt MK, Broeks A, Russell NS, Janus CPM, Krol ADG, van der Baan FH, De Bruin ML, van Eggermond AM, Dennis J, Anton Culver H, Haiman CA, Sawyer EJ, Cox A, Devilee P, Hooning MJ, Peto J, Couch FJ, Pharoah P, Orr N, Easton DF, Aleman BMP, Strong LC, Bhatia S, Cooke R, Robison LL, Swerdlow AJ, van Leeuwen FE. Genetic susceptibility to radiation-induced breast cancer after Hodgkin Lymphoma. Blood 2019; 133:1130-9 (NKI). 1093. Ore, AS, Klompmaker, S, Stackhouse, K, Solis-Velasco, M, Francken, M, Callery, MP, Kent, TS & Moser, AJ . Does surgical approach affect outcomes of enucleation for benign and low-grade pancreatic tumors? An ACS-NSQIP evaluation. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:11:1585-1591 (Amsterdam UMC). 1094. Osborne JR, Kondraciuk JD, Rice SL, Zhou X, Gharzeddine K, Knezevic A, Spratt DE, Sabra M, Larson SM, Grewal RK. Thyroid Cancer Bone Metastasis: Survival and Genomic Characteristics of a Large Tertiary Care Cohort. Clin Nucl Med 2019; 44:e465-e471 (NKI). 1095. Ossenkoppele, G & Montesinos, P . Challenges in the diagnosis and treatment of secondary acute myeloid leukemia. Critical Reviews in Oncology / Hematology 2019;138::6-13. (Amsterdam UMC). 1096. Ossenkoppele, G, Schuurhuis, GJ, van de Loosdrecht, A & Cloos, J . Can we incorporate MRD assessment into clinical practice in AML?. Best practice & research clinical haematology 2019;32:2:186-191 (Amsterdam UMC). 1097. Ossenkoppele, GJ . Midostaurin for FLT3-mutated Acute Myeloid Leukaemia – Considerations for optimal use. European Oncology and Haematology 2019;15:1:43-49 (Amsterdam UMC). 1098. Osterberg, EC, Golan, S, Pes, MPL, Eggener, SE, Petrut, B, Singh, SK, Sountoulides, P, Türkeri, LN & Wolf, JS . International and Multi-institutional Assessment of Factors Associated With Performance and Quality of Lymph Node Dissection During Radical Nephrectomy. Urology 2019;129::132-138. (Amsterdam UMC). 1099. Other members of the European-African HepatoPancreatoBiliary Association Research Collaborative, A European-African HepatoPancreatoBiliary Association (E-AHPBA)Research Collaborative Study management group, Rystedt, JML, Kleeff, JR, Salvia, R, Besselink, MG, Prasad, R, Lesurtel, M, Sturesson, C, Abu Hilal, M, Aljaiuossi, A, Antonucci, A, Ardito, F, Ausania, F, Bernon, M, Berrevoet, F, Björnsson, B, Bonsing, BA, Boonstra, EA, Bracke, B, Brusadin, R, Burda, L, Caraballo, M, Casellas- Robert, M, Çoker, A, Davide, J, de Gelder, A, de Rose, AM, Djokic, M, Dudek, K, Ekmekçigil, E, Filauro, M, Fülöp, A, Gallagher, T, Gastaca, M, Gefen, R, Giuliante, F, Habibeh, H, Halle-Smith, J, Haraldsdottir, KH, Hartman, V, Hauer, A, Hemmingsson, O, Hoskovec, D, Isaksson, B, Jonas, E, Khalaileh, A, Klug, R, Krige, J, Lignier, D, van Gulik, T, Besselink, MG, Wallach, N & Zieniewicz, K . Post cholecystectomy bile duct injury: early, intermediate or late repair with hepaticojejunostomy – an E- AHPBA multi-center study. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:12:1641–1647 (Amsterdam UMC). 1100. Ott PA, Bang YJ, Piha-Paul SA, Razak ARA, Bennouna J, Soria JC, Rugo HS, Cohen RB, O'Neil BH, Mehnert JM, Lopez J, Doi T, van Brummelen EMJ, Cristescu R, Yang P, Emancipator K, Stein K, Ayers M, Joe AK, Lunceford JK. T-Cell-Inflamed Gene-Expression Profile, Programmed Death Ligand 1 Expression, and Tumor Mutational Burden Predict Efficacy in Patients Treated With Pembrolizumab Across 20 Cancers: KEYNOTE-028. J Clin Oncol 2019; 37:318-27 (NKI). 1101. Ottenhof SR, Leone A, Djajadiningrat RS, Azizi M, Zargar K, Kidd LC, Diorio G, Mosiello G, Graafland NM, Spiess PE, Horenblas S. Surgical and Oncological Outcomes in Patients After Vascularised Flap Reconstruction for Locoregionally Advanced Penile Cancer. Eur Urol Focus 2019; 5:867-74 (NKI). 1102. Ouwerkerk, W, van den Berg, M, van der Niet, S, Limpens, J & Luiten, RM . Biomarkers, measured during therapy, for response of melanoma patients to immune checkpoint inhibitors: a systematic review. Melanoma research 2019;29:5:453-464 (Amsterdam UMC). 1103. Overbeek JA, van Herk-Sukel MPP, Vissers PAJ, van der Heijden AAWA, Bronsveld HK, Herings RMC, Schmidt MK, Nijpels G. Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries. Diabetes Care 2019; 42:434-42 (NKI). 1104. Overbeek, JA, Kuiper, JG, van der Heijden, AAWA, Labots, M, Haug, U, Herings, RMC & Nijpels, G . Sex- and site-specific differences in colorectal cancer risk among people with type 2 diabetes. International Journal of Colorectal Disease 2019;34:2:269-276 (Amsterdam UMC). 1105. Overbeek, KA, Kamps, A, van Riet, PA, Di Marco, M, Zerboni, G, van Hooft, JE, Carrara, S, Ricci, C, Gonda, TA, Schoon, E, Polkowski, M, Beyer, G, Honkoop, P, van der Waaij, LA, Casadei, R, Capurso, G, Erler, NS, Bruno, MJ, Bleiker, EMA, Cahen, DL, Bruno, MJ & PACYFIC study group . Pancreatic cyst surveillance imposes low psychological burden. Pancreatology 2019;19:8:1061-1066 (Amsterdam UMC & NKI). 1106. Overwater, A, van der Meulen, KE, Künzli, HT, Schoon, EJ, Bergman, JJGHM, Mihaela Raicu, G, Seldenrijk, KCA & Weusten, BLAM . Optimizing histopathologic evaluation of EMR specimens of Barrett's esophagus–related neoplasia: a randomized study of 3 specimen handling methods. Gastrointestinal endoscopy 2019;90:3:384-392 (Amsterdam UMC). 1107. Ozsahin, M, Slotman, BJ & Bourhis, J . Reproductive Viability of Cells Following Preoperative Stereotactic Ablative Radiotherapy. International Journal of Radiation Oncology Biology Physics 2019;105:1:233-234 (Amsterdam UMC). 1108. Pachis ST, Hiruma Y, Tromer EC, Perrakis A, Kops GJPL. Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing. Cell Rep 2019; 26:2101-12 (NKI). 1109. Page EC, Bancroft EK, Brook MN, Assel M, Hassan Al BM, Thomas S, Taylor N, Chamberlain A, Pope J, Raghallaigh HN, Evans DG, Rothwell J, Mahle L, Grindedal EMM, James P, Mascarenhas L, McKinley J, Side L, Thomas T, van Asperen C, Vasen H, Kiemeney LA, Ringelberg J, Jensen TD, Osther PJS, Helfand BT, Genova E, Oldenburg RA, Cybulski C, Wokolorczyk D, Ong KR, Huber C, Lam J, Taylor L, Salinas M, Feliubadalo L, Oosterwijk JC, van Zelst-Stams W, Cook J, Rosario DJ, Domchek S, Powers J, Buys S, O'Toole K, Ausems MGEM, Schmutzler RK, Rhiem K, Izatt L, Tripathi V, Teixeira MR, Cardoso M, Foulkes WD, Aprikian A, van Randeraad H, Davidson R, Longmuir M, Ruijs MWG, Helderman van den Enden ATJM, Adank M, Williams R, Andrews L, Murphy DG, Halliday D, Walker L, Liljegren A, Carlsson S, Azzabi A, Jobson I, Morton C, Shackleton K, Snape K, Hanson H, Harris M, Tischkowitz M, Taylor A, Kirk J, Susman R, Chen-Shtoyerman R, Spigelman A, Pachter N, Ahmed M, Ramon YC, Zgajnar J, Brewer C, Gadea N, Brady AF, van Os T, Gallagher D, Johannsson O, Donaldson A, Barwell J, Nicolai N, Friedman E, Obeid E, Greenhalgh L, Murthy V, Copakova L, Saya S, McGrath J, Cooke P, Ronlund K, Richardson K, Henderson A, Teo SH, Arun B, Kast K, Dias A, Aaronson NK, Ardern-Jones A, Bangma CH, Castro E, Dearnaley D, Eccles DM, Tricker K, Eyfjord J, Falconer A, Foster C, Gronberg H, Hamdy FC, Stefansdottir V, Khoo V, Lindeman GJ, Lubinski J, Axcrona K, Mikropoulos C, Mitra A, Moynihan C, Rennert G, Suri M, Wilson P, Dudderidge T, Offman J, Kote-Jarai Z, Vickers A, Lilja H, Eeles RA. Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers. Eur Urol 2019; 76:831-42 (NKI). 1110. Pai, SI, Faivre, S, Licitra, L, Machiels, J-P, Vermorken, JB, Bruzzi, P, Gruenwald, V, Giglio, RE, Leemans, CR, Seiwert, TY & Soulieres, D . Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040). Journal for Immunotherapy of Cancer 2019;7:1: (Amsterdam UMC). 1111. Paiella, S, de Pastena, M, Korrel, M, Pan, TL, Butturini, G, Nessi, C, de Robertis, R, Landoni, L, Casetti, L, Giardino, A, Busch, O, Pea, A, Esposito, A, Besselink, M, Bassi, C & Salvia, R . Long term outcome after minimally invasive and open Warshaw and Kimura techniques for spleen-preserving distal pancreatectomy: International multicenter retrospective study. European journal of surgical oncology 2019;45:9:1668-1673 (Amsterdam UMC). 1112. Palic S, Bhairosing P, Beijnen JH, Dorlo TPC. Host-mediated activity of miltefosine in leishmaniasis through immunomodulation: a systematic review. Antimicrob Agents Chemother 2019; 63:e02507- 18 (NKI). 1113. Palit SA, Vis D, Stelloo S, Lieftink C, Prekovic S, Bekers E, Hofland I, Sustic T, Wolters L, Beijersbergen R, Bergman AM, Gyorffy B, Wessels LF, Zwart W, van der Heijden MS. TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth. Elife 2019; 8:e47430 (NKI). 1114. Palma, DA, Olson, R, Harrow, S, Correa, RJM, Schneiders, F, Haasbeek, CJA, Rodrigues, GB, Lock, M, Yaremko, BP, Bauman, GS, Ahmad, B, Schellenberg, D, Liu, M, Gaede, S, Laba, J, Mulroy, L, Senthi, S, Louie, AV, Swaminath, A, Chalmers, A, Warner, A, Slotman, BJ, de Gruijl, TD, Allan, A & Senan, S . Stereotactic ablative radiotherapy for the comprehensive treatment of 4-10 oligometastatic tumors (SABR-COMET-10). BMC Cancer 2019;19:1: (Amsterdam UMC). 1115. Palma, DA, Olson, R, Harrow, S, Gaede, S, Louie, AV, Haasbeek, C, Mulroy, L, Lock, M, Rodrigues, GB, Yaremko, BP, Schellenberg, D, Ahmad, B, Griffioen, G, Senthi, S, Swaminath, A, Kopek, N, Liu, M, Moore, K, Currie, S, Bauman, GS, Warner, A & Senan, S . Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET). Lancet 2019;393:10185:2051-2058 (Amsterdam UMC). 1116. Pandit R, Cianci D, Ter Hark SE, Winter-van Rossum I, Ebdrup BH, Broberg BV, Garcia-Portilla MP, Bobes J, Vinkers CH, Kahn RS, Guloksuz S, Huitema ADR, Luykx JJ. Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTIMISE cohort). Acta Psychiatr Scand 2019; 140:283-90 (NKI). 1117. Pantelidou C, Sonzogni O, De Oliveria Teveira M, Mehta AK, Kothari A, Wang D, Visal T, Li MK, Pinto J, Castrillon JA, Cheney EM, Bouwman P, Jonkers J, Rottenberg S, Guerriero JL, Wulf GM, Shapiro GI. PARP Inhibitor Efficacy Depends on CD8(+) T-cell Recruitment via Intratumoral STING Pathway Activation in BRCA-Deficient Models of Triple-Negative Breast Cancer. Cancer Discov 2019; 9:722-37 (NKI). 1118. Passera, S, Contarino, V, Scarfone, G, Scola, E, Fontana, C, Peccatori, F, Cinnante, C, Counsell, S, Ossola, M, Pisoni, S, Pesenti, N, Grossi, E, Amant, F, Mosca, F, Triulzi, F & Fumagalli, M . Effects of in- utero exposure to chemotherapy on fetal brain growth. International journal of gynecological cancer 2019;29:7:1195-1202 (Amsterdam UMC & NKI). 1119. Peinemann, F, van Dalen, EC, Enk, H & Tytgat, GAM . Anti-GD2 antibody-containing immunotherapy postconsolidation therapy for people with high-risk neuroblastoma treated with autologous haematopoietic stem cell transplantation. Cochrane database of systematic reviews (Online) 2019;2019:4: (Amsterdam UMC). 1120. PelvEx Collaborative, Collaborators (80), Aalbers AGJ, Beets GL. Surgical and Survival Outcomes Following Pelvic Exenteration for Locally Advanced Primary Rectal Cancer: Results from an International Collaboration. Ann Surg 2019; 269:315-21 (NKI). 1121. Pereira BA, Vennin C, Papanicolaou M, Chambers CR, Herrmann D, Morton JP, Cox TR, Timpson P. CAF Subpopulations: A New Reservoir of Stromal Targets in Pancreatic Cancer. Trends Cancer 2019; 5:724-41 (NKI). 1122. Persoon, S, Buffart, LM, Chinapaw, MJM, Nollet, F, Frings-Dresen, MH, Koning, S, Kersten, MJ & Tamminga, SJ . Return to work experiences of patients treated with stem cell transplantation for a hematologic malignancy. Supportive care in cancer 2019;27:8:2987-2997 (Amsterdam UMC). 1123. Peters HE, Johnson BN, Ehli EA, Micha D, Verhoeven MO, Davies GE, Dekker JJML, Overbeek A, Berg MHVD, van Dulmen-den Broeder E, van Leeuwen FE, ijatovic V, oomsma DI, ambalk CB. Low prevalence of male microchimerism in women with Mayer-Rokitansky-Kuster-Hauser syndrome. Hum Reprod 2019; 34:1117-25 (NKI). 1124. Peters S, Dafni U, Boyer M, De Ruysscher D, Faivre-Finn C, Felip E, Garrido P, Girard N, Guckenberger M, Haanen J, Le Pechoux C, Mornex F, Ozsahin M, Paz-Ares L, Planchard D, Raben D, Ramalingam S, Reck M, Smit E, Stahel R, Stenzinger A, Swanton C, Vallone S, Garassino MC. Position of a panel of international lung cancer experts on the approval decision for use of durvalumab in stage III non- small-cell lung cancer (NSCLC) by the Committee for Medicinal Products for Human Use (CHMP). Ann Oncol 2019; 30:161-5 (NKI). 1125. Peters S, Reck M, Smit EF, Mok T, Hellmann MD. How to Make the Best Use of Immunotherapy as First-Line Treatment for Advanced/Metastatic Non-Small-Cell Lung Cancer. Ann Oncol 2019; 30:884- 96 (NKI). 1126. Peters, S, Felip, E, Dafni, U, Belka, C, Guckenberger, M, Irigoyen, A, Nadal, E, Becker, A, Vees, H, Pless, M, Martinez-Marti, A, Tufman, A, Lambrecht, M, Andratschke, N, Piguet, AC, Kassapian, M, Roschitzki-Voser, H, Rabaglio-Poretti, M, Stahel, RA, Vansteenkiste, J & De Ruysscher, D . Safety evaluation of nivolumab added concurrently to radiotherapy in a standard first line chemo- radiotherapy regimen in stage III non-small cell lung cancer—The ETOP NICOLAS trial. Lung Cancer 2019;133::83-87. (Amsterdam UMC). 1127. Peters, S, Reck, M, Smit, EF, Mok, T & Hellmann, MD . How to make the best use of immunotherapy as first-line treatment of advanced/metastatic non-small-cell lung cancer. Annals of Oncology 2019;30:6:884-896 (Amsterdam UMC). 1128. Petersen JF, Arends CR, van der Noort, V, Al-Mamgani A, de Boer JP, Stuiver MM, van den Brekel MWM. Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer. Oral Oncol 2019; 95:143-9 (NKI). 1129. Petersen JF, Berlanga A, Stuiver MM, Hamming-Vrieze O, Hoebers F, Lambin P, van den Brekel MWM. Improving decision making in larynx cancer by developing a decision aid: A mixed methods approach. Laryngoscope 2019; 129:2733-9 (NKI). 1130. Petersen JF, Lansaat L, Hilgers F, van den Brekel M. Solving periprosthetic leakage with a novel prosthetic device. Laryngoscope 2019; 129:2299-302 (NKI). 1131. Petersen JF, Lansaat L, Timmermans AJ, van der Noort V, Hilgers FJM, van den Brekel MWM. Postlaryngectomy prosthetic voice rehabilitation outcomes in a consecutive cohort of 232 patients over a 13-year period. Head Neck 2019; 41:623-31 (NKI). 1132. Petersen JF, Pezier TF, van Dieren JM, van der Noort V, van Putten T, Bril SI, Janssen L, Dirven R, van den Brekel MWM, De Bree R. Dilation after laryngectomy: Incidence, risk factors and complications. Oral Oncol 2019; 91:107-12 (NKI). 1133. Peyronnet B, Seisen T, Dominguez-Escrig JL, Bruins HM, Yuan CY, Lam T, MacLennan S, N'Dow J, Babjuk M, Comperat E, Zigeuner R, Sylvester RJ, Burger M, Mostafid H, van Rhijn BWG, Gontero P, Palou J, Shariat SF, Roupret M. Oncological Outcomes of Laparoscopic Nephroureterectomy Versus Open Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: An European Association of Urology Guidelines Systematic Review. Eur Urol Focus 2019; 5:205-23 (NKI). 1134. Pfaehler, E, Beukinga, RJ, de Jong, JR, Slart, RHJA, Slump, CH, Dierckx, RAJO & Boellaard, R . Repeatability of 18F-FDG PET radiomic features: A phantom study to explore sensitivity to image reconstruction settings, noise, and delineation method. Medical Physics 2019;46:2:665-678 (Amsterdam UMC). 1135. Pfaehler, E, Zwanenburg, A, de Jong, JR & Boellaard, R . RACAT: An open source and easy to use radiomics calculator tool. PLoS ONE 2019;14:2: (Amsterdam UMC). 1136. Piai, V, Prins, JB, Verdonck-de Leeuw, IM, Leemans, CR, Terhaard, CHJ, Langendijk, JA, Baatenburg de Jong, RJ, Smit, JH, Takes, RP & Kessels, RPC . Assessment of Neurocognitive Impairment and Speech Functioning before Head and Neck Cancer Treatment. JAMA Otolaryngology - Head and Neck Surgery 2019;145:3:251-257 (Amsterdam UMC). 1137. Pich O, Muinos F, Lolkema MP, Steeghs N, Gonzalez-Perez A, Lopez-Bigas N. The mutational footprints of cancer therapies. Nat Genet 2019; 51:1732-40 (NKI). 1138. Pierrard V, Lebdai S, Kleinclauss F, Azzouzi AR, Terrier JE, Fortier E, Joniau S, van der Poel H, Salomon G, Casanova J, Medina-Lopez RA, Potiron E, Rigaud J, Vincendeau S, Rassweiler J, Villers A, Gaston R, Saussine C, Giai J, Gaillac B, Emberton M, Ruffion A. Radical prostatectomy after vascular-targeted photodynamic therapy (VTP) with TOOKAD(R) : feasibility, early and intermediate results. J Urol 2019; 201:315-21 (NKI). 1139. Pieterse, AH, Kunneman, M, van den Hout, WB, Baas-Thijssen, M, Geijsen, ED, Ceha, HM, Muller, KM, van der Linden, YM, Marijnen, CAM & Stiggelbout, AM . Patient explicit consideration of tradeoffs in decision making about rectal cancer treatment: benefits for decision process and quality of life. Acta oncologica (Stockholm, Sweden) 2019;58:7:1069-1076 (Amsterdam UMC). 1140. Pilzecker B, Buoninfante OA, Jacobs H. DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy. Nucleic Acids Res 2019; 47:7163-81 (NKI). 1141. Pilzecker B, Jacobs H. Mutating for Good: DNA Damage Responses During Somatic Hypermutation. Front Immunol 2019; 10:438 (NKI). 1142. Pimentel-Nunes, P, Libânio, D, Marcos-Pinto, R, Areia, M, Leja, M, Esposito, G, Garrido, M, Kikuste, I, Megraud, F, Matysiak-Budnik, T, Annibale, B, Dumonceau, J-M, Barros, R, Fléjou, J-F, Carneiro, FT, van Hooft, JE, Kuipers, EJ & Dinis-Ribeiro, M . Management of epithelial precancerous conditions and lesions in the stomach (MAPS II): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG), European Society of Pathology (ESP), and Sociedade Portuguesa de Endoscopia Digestiva (SPED) guideline update 2019. Endoscopy 2019;51:4:365-388 (Amsterdam UMC). 1143. Pimentel-Nunes, P, Pioche, M, Albéniz, E, Berr, F, Deprez, P, Ebigbo, A, Dewint, P, Haji, A, Panarese, A, Weusten, BLAM, Dekker, E, East, JE, Sanders, DS, Johnson, G, Arvanitakis, M, Ponchon, T, Dinis- Ribeiro, MR & Bisschops, R . Curriculum for endoscopic submucosal dissection training in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy 2019;51:10:980-992 (Amsterdam UMC). 1144. Ping, Z, Chen, S, Hermans, SJF, Kenswil, KJG, Feyen, J, van Dijk, C, Bindels, EMJ, Mylona, AM, Adisty, NM, Hoogenboezem, RM, Sanders, MA, Cremers, EMP, Lindenbergh-Kortleve, DJ, Samsom, JN, van de Loosdrecht, AA & Raaijmakers, MHGP . Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes. Leukemia 2019;33:2:536-541 (Amsterdam UMC). 1145. Pirozzolo, G, Gisbertz, SS, Castoro, C, van Berge Henegouwen, MI & Scarpa, M . Neutrophil-to- lymphocyte ratio as prognostic marker in esophageal cancer: A systematic review and meta-analysis. Journal of thoracic disease 2019;11:7:3136-3145 (Amsterdam UMC). 1146. Pirro, M, Schoof, E, van Vliet, SJ, Rombouts, Y, Stella, A, de Ru, A, Mohammed, Y, Wuhrer, M, van Veelen, PA & Hensbergen, PJ . Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells. Journal of Proteome Research 2019;18:3:1125-1132 (Amsterdam UMC). 1147. Plante, M, van Trommel, N, Lheureux, S, Oza, AM, Wang, L, Sikorska, K, Ferguson, SE, Han, K & Amant, F . FIGO 2018 stage IB2 (2-4 cm) Cervical cancer treated with Neo-adjuvant chemotherapy followed by fertility Sparing Surgery (CONTESSA); Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertility (NEOCON-F). A PMHC, DGOG, GCIG/CCRN and multicenter study. International journal of gynecological cancer 2019;29:5:969-975 (Amsterdam UMC & NKI). 1148. Plat, VD, Bootsma, BT, Neal, M, Nielsen, K, Sonneveld, DJA, Tersteeg, JJC, Crolla, RMPH, van Dam, DA, Cense, HA, Stockmann, HBAC, Covington, JA, de Meij, TGJ, Tuynman, JB, de Boer, NKH & Daams, F . Urinary volatile organic compound markers and colorectal anastomotic leakage. Colorectal Disease 2019;21:11:1249-1258 (Amsterdam UMC). 1149. Plat, VD, Bootsma, BT, van der Wielen, N, van der Peet, DL & Daams, F . Autologous activated fibrin sealant for the esophageal anastomosis: a feasibility study. Journal of Surgical Research 2019;234::49-53. (Amsterdam UMC). 1150. Plat, VD, van Gaal, N, Covington, JA, Neal, M, de Meij, TGJ, van der Peet, DL, Zonderhuis, B, Kazemier, G, de Boer, NKH & Daams, F . Non-Invasive Detection of Anastomotic Leakage Following Esophageal and Pancreatic Surgery by Urinary Analysis. Digestive Surgery 2019;36:2:173-180 (Amsterdam UMC). 1151. Platzbecker, U, Fenaux, P, Adès, L, Giagounidis, A, Santini, V, van de Loosdrecht, AA, Bowen, D, de Witte, T, Garcia-Manero, G, Hellström-Lindberg, E, Germing, U, Stauder, R, Malcovati, L, Sekeres, MA, Steensma, DP & Gloaguen, S . Proposals for revised IWG 2018 hematological response criteria in patients with MDS included in clinical trials. Blood 2019;133:10:1020-1030 (Amsterdam UMC). 1152. Pluim D, Ros W, Miedema IHC, Beijnen JH, Schellens JHM. Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab. Cytometry A 2019; 95:1053-65 (NKI). 1153. Pluim D, Ros W, van Bussel MTJ, Brandsma D, Beijnen JH, Schellens JHM. Enzyme linked immunosorbent assay for the quantification of nivolumab and pembrolizumab in human serum and cerebrospinal fluid. J Pharm Biomed Anal 2019; 164:128-34 (NKI). 1154. Plumb AAO, Lambregts D, Bellini D, Stoker J, Taylor S. Making useful clinical guidelines: the ESGAR perspective. Eur Radiol 2019; 29:3757-60 [Editorial] (NKI). 1155. Poel D, Boyd LNC, Beekhof R, Schelfhorst T, Pham TV, Piersma SR, Knol JC, Jimenez CR, Verheul HMW, Buffart TE. Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells. Cells 2019; 8:E1111 (NKI). 1156. Poelemeijer YQM, Marang-van de Mheen PJ, Wouters MWJM, Nienhuijs SW, Liem RSL. Textbook Outcome: an Ordered Composite Measure for Quality of Bariatric Surgery. Obes Surg 2019; 29:1287- 94 (NKI). 1157. Poell, JB, Mendeville, M, Sie, D, Brink, A, Brakenhoff, RH & Ylstra, B . ACE. Bioinformatics 2019;35:16:2847-2849 (Amsterdam UMC). 1158. Polman, NJ, de Haan, Y, Veldhuijzen, NJ, Heideman, DAM, de Vet, HCW, Meijer, CJLM, Massuger, LFAG, van Kemenade, FJ & Berkhof, J . Experience with HPV self-sampling and clinician-based sampling in women attending routine cervical screening in the Netherlands. Preventive Medicine 2019;125::5-11. (Amsterdam UMC). 1159. Polman, NJ, Ebisch, RMF, Heideman, DAM, Melchers, WJG, Bekkers, RLM, Molijn, AC, Meijer, CJLM, Quint, WGV, Snijders, PJF, Massuger, LFAG, van Kemenade, FJ & Berkhof, J . Performance of human papillomavirus testing on self-collected versus clinician-collected samples for the detection of cervical intraepithelial neoplasia of grade 2 or worse. Lancet Oncology 2019;20:2:229-238 (Amsterdam UMC). 1160. Polman, NJ, Snijders, PJF, Kenter, GG, Berkhof, J & Meijer, CJLM . HPV-based cervical screening: Rationale, expectations and future perspectives of the new Dutch screening programme. Preventive Medicine 2019;119::108-117. (Amsterdam UMC). 1161. Polman, NJ, Veldhuijzen, NJ, Heideman, DAM, Snijders, PJF, Meijer, CJLM & Berkhof, J . Management of HPV-positive women in cervical screening using results from two consecutive screening rounds. International Journal of Cancer 2019;144:9:2339-2346 (Amsterdam UMC). 1162. Pont, MJ, Oostvogels, R, van Bergen, CAM, van der Meijden, ED, Honders, MW, Bliss, S, Jongsma, MLM, Lokhorst, HM, Frederik Falkenburg, JH, Mutis, T, Griffioen, M & Spaapen, RM . T cells specific for an unconventional natural antigen fail to recognize leukemic cells. Cancer Immunology Research 2019;7:5:797-804 (Amsterdam UMC). 1163. Poort, H, Onghena, P, Abrahams, HJG, Jim, HSL, Jacobsen, PB, Blijlevens, NMA & Knoop, H . Cognitive Behavioral Therapy for Treatment-Related Fatigue in Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitors: A Mixed-Method Study. Journal of clinical psychology in medical settings 2019;26:4:440-448 (Amsterdam UMC). 1164. Poot, AJ, Adamzek, KWA, Windhorst, AD, Vosjan, MJWD, Kropf, S, Wester, H-J, van Dongen, GAMS & Vugts, DJ . Fully Automated 89 Zr Labeling and Purification of Antibodies. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2019 (Amsterdam UMC). 1165. Popov, A, Druy, A, Shorikov, E, Verzhbitskaya, T, Solodovnikov, A, Saveliev, L, Tytgat, GAM, Tsaur, G & Fechina, L . Prognostic value of initial bone marrow disease detection by multiparameter flow cytometry in children with neuroblastoma. Journal of cancer research and clinical oncology 2019;145:2:535-542 (Amsterdam UMC). 1166. Poramba-Liyanage DW, Korthout T, van Leeuwen F. Epi-ID: Systematic and Direct Screening for Chromatin Regulators in Yeast by Barcode-ChIP-Seq. Methods Mol Biol 2019; 2049:87-103 (NKI). 1167. Porta C, Cosmai L, Leibovich BC, Powles T, Gallieni M, Bex A. The adjuvant treatment of kidney cancer: a multidisciplinary outlook. Nat Rev Nephrol 2019; 15:423-33 (NKI). 1168. Postema, FAM, Bliek, J, van Noesel, CJM, van Zutven, LJCM, Oosterwijk, JC, Hopman, SMJ, Merks, JHM & Hennekam, RC . Multiple tumors due to mosaic genome-wide paternal uniparental disomy. Pediatric blood & cancer 2019;66:6: (Amsterdam UMC). 1169. Powles T, Kockx M, Rodriguez-Vida A, Duran I, Crabb SJ, van der Heijden MS, Szabados B, Pous AF, Gravis G, Herranz UA, Protheroe A, Ravaud A, Maillet D, Mendez MJ, Suarez C, Linch M, Prendergast A, Van Dam PJ, Stanoeva D, Daelemans S, Mariathasan S, Tea JS, Mousa K, Banchereau R, Castellano D. Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial. Nat Med 2019; 25:1706-14 (NKI). 1170. Prasetya, H, Jansen, SM, Marquering, HA, van Leeuwen, TG, Gisbertz, SS, de Bruin, DM & van Bavel, E . Estimation of microvascular perfusion after esophagectomy: a quantitative model of dynamic fluorescence imaging. Medical & biological engineering & computing 2019;57:9:1889–1900 (Amsterdam UMC). 1171. Prasetyanti, PR, van Hooff, SR, van Herwaarden, T, de Vries, N, Kalloe, K, Rodermond, H, van Leersum, R, de Jong, JH, Franitza, M, Nürnberg, P, Todaro, M, Stassi, G & Medema, JP . Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models. International journal of cancer. Journal international du cancer 2019;144:2:366-371 (Amsterdam UMC). 1172. Preuss, K-D, Hollak, CEM, Fadle, N, van Oers, M, Regitz, E & Pfreundschuh, M . Saposin C is a frequent target of paraproteins in Gaucher disease-associated MGUS/multiple myeloma. British journal of haematology 2019;184:3:384-391 (Amsterdam UMC). 1173. Priesterbach-Ackley, LP, Wesseling, P, Snijders, TJ, de Vos, FYFL & de Leng, WWJ . Molecular tools for the pathologic diagnosis of central nervous system tumors. Neuro-Oncology Practice 2019;6:1:42461 (Amsterdam UMC). 1174. Priestley P, Baber J, Lolkema MP, Steeghs N, de Bruijn E, Shale C, Duyvesteyn K, Haidari S, van Hoeck A, Onstenk W, Roepman P, Voda M, Bloemendal HJ, Tjan-Heijnen VCG, van Herpen CML, Labots M, Witteveen PO, Smit EF, Sleijfer S, Voest EE, Cuppen E. Pan-cancer whole-genome analyses of metastatic solid tumours. Nature 2019; 575:210-6 (NKI). 1175. Puppe J, Opdam M, Schouten PC, Jozwiak K, Lips EH, Severson T, van de Ven M, Brambillasca CS, Bouwman P, van Tellingen O, Bernards R, Wesseling J, Eichler C, Thangarajah F, Malter W, Pandey GK, Ozretic L, Caldas C, van Lohuizen M, Hauptmann M, Rhiem K, Hahnen E, Reinhardt HC, Buttner R, Mallmann P, Schomig-Markiefka B, Schmutzler RK, Linn SC, Jonkers J. EZH2 is overexpressed in BRCA1-like breast tumors and predictive for sensitivity to high-dose platinum-based chemotherapy. Clin Cancer Res 2019; 25:4351-62 (NKI). 1176. Putora PM, De Ruysscher D, Glatzer M, Widder J, Van Houtte P, Troost EGC, Slotman BJ, Ramella S, Pottgen C, Peeters S, Nestle U, McDonald F, Le Pechoux C, Dziadziuszko R, Belderbos J, Faivre-Finn C. The role of postoperative thoracic radiotherapy and prophylactic cranial irradiation in early stage small cell lung cancer: Patient selection among ESTRO experts. Radiother Oncol 2019; 145:45-8 (NKI). 1177. Putora, PM, Glatzer, M, Belderbos, J, Besse, B, Blackhall, F, Califano, R, Cappuzzo, F, de Marinis, F, Dziadziuszko, R, Felip, E, Faivre-Finn, C, Früh, M, Garrido, P, le Pechoux, C, McDonald, F, Nestle, U, Novello, S, O‘Brien, M, Paz Ares, L, Peeters, S, Pöttgen, C, Ramella, S, Reck, M, Slotman, B, Troost, EGC, van Houtte, P, Westeel, V, Widder, J, Mornex, F & de Ruysscher, D . Prophylactic cranial irradiation in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts. Radiotherapy and Oncology 2019;133::163-166 (Amsterdam UMC & NKI). 1178. Putora, PM, Glatzer, M, de Ruysscher, D, Faivre-Finn, C, Belderbos, J, Besse, B, Blackhall, F, Califano, R, Cappuzzo, F, de Marinis, F, Dziadiuszko, R, Felip, E, Früh, M, Garrido, P, le Pechoux, C, McDonald, F, Nestle, U, Novello, S, Brien, MO, Paz Ares, L, Peeters, S, Pöttgen, S, Ramella, S, Reck, M, Troost, EGC, van Houtte, P, Westeel, V, Widder, J, Mornex, F & Slotman, BJ . Consolidative thoracic radiotherapy in stage IV small cell lung cancer: Selection of patients amongst European IASLC and ESTRO experts. Radiotherapy and Oncology 2019;135::74-77 (Amsterdam UMC & NKI). 1179. Qendri, V, Bogaards, JA & Berkhof, J . Pricing of HPV vaccines in European tender-based settings. The European Journal of Health Economics 2019;20:2:271-280 (Amsterdam UMC). 1180. Qian, F, Rookus, MA, Leslie, G, Risch, HA, Greene, MH, Aalfs, CM, Adank, MA, Adlard, J, Agnarsson, BA, Ahmed, M, Aittomäki, K, Andrulis, IL, Arnold, N, Arun, BK, Ausems, MGEM, Azzollini, J, Barrowdale, D, Barwell, J, Benitez, J, Białkowska, K, Bonadona, V, Borde, J, Borg, A, Bradbury, AR, Brunet, J, Buys, SS, Caldés, T, Caligo, MA, Campbell, I, Carter, J, Chiquette, J, Chung, WK, Claes, KBM, Collée, JM, Collonge-Rame, M-A, Couch, FJ, Daly, MB, Delnatte, C, Diez, O, Domchek, SM, Dorfling, CM, Eason, J, Easton, DF, Eeles, R, Engel, C, Evans, DG, Faivre, L, Meijers-Heijboer, HEJ, Oosterwijk, JC, van Engelen, K, EMBRACE Collaborators, KConFab Investigators, GEMO Study Collaborators & HEBON Investigators . Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. British Journal of Cancer 2019;121:: (Amsterdam UMC & NKI). 1181. Qian, F, Wang, S, Mitchell, J, McGuffog, L, Barrowdale, D, Leslie, G, Oosterwijk, JC, Chung, WK, Evans, DG, Engel, C, Kast, K, Aalfs, CM, Adank, MA, Adlard, J, Agnarsson, BA, Aittomäki, K, Alducci, E, Andrulis, IL, Arun, BK, Ausems, MGEM, Azzollini, J, Barouk-Simonet, E, Barwell, J, Belotti, M, Benitez, J, Berger, A, Borg, A, Bradbury, AR, Brunet, J, Buys, SS, Caldes, T, Caligo, MA, Campbell, I, Caputo, SM, Chiquette, J, Claes, KBM, Margriet Collée, J, Couch, FJ, Coupier, I, Daly, MB, Davidson, R, Diez, O, Domchek, SM, Donaldson, A, Dorfling, CM, Eeles, R, Feliubadaló, L, Foretova, L, Meijers-Heijboer, HEJ, van Engelen, K, HEBON, EMBRACE, GEMO Study Collaborators, Greene, MH, Antoniou, AC, Goldgar, DE, Olopade, OI, Rebbeck, TR & Huo, D . Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. Journal of the National Cancer Institute 2019;111:4:350-364 (Amsterdam UMC & NKI). 1182. Raaijmakers JA, Medema RH. Killing a zombie: a full deletion of the BUB1 gene in HAP1 cells. EMBO J 2019; 38:e102423 [Letter] (NKI). 1183. Rådestad, E, Klynning, C, Stikvoort, A, Mogensen, O, Nava, S, Magalhaes, I & Uhlin, M . Immune profiling and identification of prognostic immune-related risk factors in human ovarian cancer. OncoImmunology 2019;8:2: (Amsterdam UMC). 1184. Radonic, T, Dickhoff, C, Mino-Kenudson, M, Lely, R, Paul, R & Thunnissen, E . Gross handling of pulmonary resection specimen: Maintaining the 3-dimensional orientation. Journal of Thoracic Disease 2019;11::S37-S44. (Amsterdam UMC). 1185. Ramayanti, O, Verkuijlen, SAWM, Novianti, P, Scheepbouwer, C, Misovic, B, Koppers-Lalic, D, van Weering, J, Beckers, L, Adham, M, Martorelli, D, Middeldorp, JM & Pegtel, DM . Vesicle-bound EBV- BART13-3p miRNA in circulation distinguishes nasopharyngeal from other head and neck cancer and asymptomatic EBV-infections. International Journal of Cancer 2019;144:10:2555-2566 (Amsterdam UMC). 1186. Ramovs V, Secades P, Song JY, Thijssen B, Kreft M, Sonnenberg A. Absence of integrin alpha3beta1 promotes the progression of HER2-driven breast cancer in vivo. Breast Cancer Res 2019; 21:63 (NKI). 1187. Raphael DB, Ter Stege JA, Russell NS, Boersma LJ, van der Weijden T. What do patients and health care professionals view as important attributes in radiotherapy decisions? Input for a breast cancer patient decision aid. Breast 2019; 49:149-56 (NKI). 1188. Rassam, F, Cieslak, KP, Beuers, UHW, van Gulik, TM & Bennink, RJ . Stress test of liver function using technetium-99m-mebrofenin hepatobiliary scintigraphy. Nuclear medicine communications 2019;40:4:388-392 (Amsterdam UMC). 1189. Rassam, F, Olthof, PB, Richardson, H, van Gulik, TM & Bennink, RJ . Practical guidelines for the use of technetium-99m mebrofenin hepatobiliary scintigraphy in the quantitative assessment of liver function. Nuclear medicine communications 2019;40:4:297-307 (Amsterdam UMC). 1190. Rassam, F, Olthof, PB, Takkenberg, BR, Beuers, U, Klümpen, H-J, Bennink, RJ, van Lienden, KP, Besselink, MG, Busch, OR, Verheij, J & van Gulik, TM . Scintigraphic liver function and transient elastography in the assessment of patients with resectable hepatocellular carcinoma. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:5:626-635 (Amsterdam UMC). 1191. Rassam, F, Uz, ZH, van Lienden, KP, Ince, C, Bennink, RJ & van Gulik, TM . Quantitative assessment of liver function using hepatobiliary scintigraphy: The effect of microcirculatory alterations after portal vein embolization. Nuclear medicine communications 2019;40:7:720-726 (Amsterdam UMC). 1192. Ratnayake CBB, Fles R, Tan IB, Baijens LWJ, Pilz W, Meeuwis CA, Janssen-van Det PHE, van Son R, van den Brekel MWM. Multicenter randomized crossover trial evaluating the provox luna in laryngectomized subjects. Laryngoscope 2019; 129:2354-60 (NKI). 1193. Raut CP, Callegaro D, Miceli R, Barretta F, Rutkowski P, Blay JY, Lahat G, Strauss DC, Gonzalez R, Ahuja N, Grignani G, Quagliuolo V, Stoeckle E, De Paoli A, Pillarisetty VG, Nessim C, Swallow C, Bagaria SP, Canter RJ, Mullen JT, Gelderblom H, Pennacchioli E, van Coevorden F, Cardona K, Fiore M, Fairweather M, Gronchi A. Predicting Survival in Patients Undergoing Resection for Locally Recurrent Retroperitoneal Sarcoma: A Study and Novel Nomogram from TARPSWG. Clin Cancer Res 2019; 25:2664-71 (NKI). 1194. Rauwerdink, A, Jansen, M, de Borgie, CAJM, Bemelman, WA, Daams, F, Schijven, MP & Buskens, CJ . Improving enhanced recovery after surgery (ERAS): ERAS APPtimize study protocol, a randomized controlled trial investigating the effect of a patient-centred mobile application on patient participation in colorectal surgery. BMC surgery 2019;19:1: (Amsterdam UMC). 1195. Ray-Coquard, I, Trama, A, Seckl, MJ, Fotopoulou, C, Pautier, P, Pignata, S, Kristensen, G, Mangili, G, Falconer, H, Massuger, L, Sehouli, J, Pujade-Lauraine, E, Lorusso, D, Amant, F, Rokkones, E, Vergote, I, Ledermann, JA, AUTHOR GROUP, Hackl, M, van Eycken, E, Henau, K, Dimitrova, N, Sekerija, M, Dušek, L, Mägi, M, Malila, N, Leinonen, M, Velten, M, Troussard, X, Bouvier, V, Guizard, A-V, Bouvier, A-M, Arveux, P, Maynadié, M, Woronoff, A-S, Robaszkiewicz, M, Baldi, I, Monnereau, A, Tretarre, B, Colonna, M, Molinié, F, Bara, S, Schvartz, C, Lapôtre-Ledoux, B, Grosclaude, P, Stabenow, R, Luttmann, S, Nennecke, A, Engel, J, Schubert-Fritschle, G & Heidrich, J . Rare ovarian tumours: Epidemiology, treatment challenges in and outside a network setting. European journal of surgical oncology 2019;45:1:67-74 (Amsterdam UMC & NKI). 1196. Reedijk, AMJ, Klein, K, Coebergh, JWW, Kremer, LC, Dinmohamed, AG, de Haas, V, Versluijs, AB, Ossenkoppele, GJ, Beverloo, HB, Pieters, R, Zwaan, CM, Kaspers, GJL & Karim-Kos, HE . Improved survival for children and young adolescents with acute myeloid leukemia: a Dutch study on incidence, survival and mortality. Leukemia 2019;33:6:1349-1359 (Amsterdam UMC). 1197. Reiniers, MJ, de Haan, L, Weijer, R, Wiggers, JK, Jongejan, A, Moerland, PD, Alles, LK, van Kampen, AHC, van Gulik, TM, Heger, M & van Golen, RF . Effect of preoperative biliary drainage on cholestasis-associated inflammatory and fibrotic gene signatures in perihilar cholangiocarcinoma. British journal of surgery 2019;106:1:55-58 (Amsterdam UMC). 1198. Ren, Z, Ahn, JH, Liu, H, Tsai, Y-H, Bhanu, NV, Koss, B, Allison, DF, Ma, A, Storey, AJ, Wang, P, Mackintosh, SG, Edmondson, RD, Groen, RWJ, Martens, AC, Garcia, BA, Tackett, AJ, Jin, J, Cai, L, Zheng, D & Wang, GG . PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation. Blood 2019;134:14:1176-1189 (Amsterdam UMC). 1199. Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M. Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy. Cell Rep 2019; 29:135-50 (NKI). 1200. Rensen, N, Steur, LM, Schepers, SA, Merks, JH, Moll, AC, Kaspers, GJ, Grootenhuis, MA & van Litsenburg, RR . Gender-specific differences in parental health-related quality of life in childhood cancer. Pediatric Blood and Cancer 2019;66:7: (Amsterdam UMC). 1201. Repici, A, Wallace, MB, East, JE, Sharma, P, Ramirez, FC, Bruining, DH, Young, M, Gatof, D, Irene (Mimi) Canto, M, Marcon, N, Cannizzaro, R, Kiesslich, R, Rutter, M, Dekker, E, Siersema, PD, Spaander, M, Kupcinskas, L, Jonaitis, L, Bisschops, R, Radaelli, F, Bhandari, P, Wilson, A, Early, D, Gupta, N, Vieth, M, Lauwers, GY, Rossini, M & Hassan, C . Efficacy of Per-oral Methylene Blue Formulation for Screening Colonoscopy. Gastroenterology 2019;156:8:2198-2207 (Amsterdam UMC). 1202. Reuling, EMBP, Dickhoff, C, Plaisier, PW, Bonjer, HJ & Daniels, JMA . Endobronchial and surgical treatment of pulmonary carcinoid tumors. Lung Cancer 2019;134::85-95. (Amsterdam UMC). 1203. Reumkens K, Tummers MHE, Gietel-Habets JJG, van Kuijk SMJ, Aalfs CM, van Asperen CJ, Ausems MGEM, Collee M, Dommering CJ, Kets CM, van der Kolk LE, Oosterwijk JC, Tjan-Heijnen VCG, van der Weijden T, de Die-Smulders CEM, van Osch LADM. Online decision support for persons having a genetic predisposition to cancer and their partners during reproductive decision-making. J Genet Couns 2019; 28:533-42 (NKI). 1204. Reumkens, K, Tummers, MHE, Gietel-Habets, JJG, van Kuijk, SMJ, Aalfs, CM, van Asperen, CJ, Ausems, MGEM, Collée, M, Dommering, CJ, Kets, CM, van der Kolk, LE, Oosterwijk, JC, Tjan-Heijnen, VCG, van der Weijden, T, de Die-Smulders, CEM & van Osch, LADM . The development of an online decision aid to support persons having a genetic predisposition to cancer and their partners during reproductive decision-making: a usability and pilot study. Familial Cancer 2019;18:1:137-146 (Amsterdam UMC & NKI). 1205. Rex, DK & Dekker, E . How we resect colorectal polyps <20 mm in size. Gastrointestinal endoscopy 2019;89:3:449-452 (Amsterdam UMC). 1206. Ricke, J, Klümpen, HJ, Amthauer, H, Bargellini, I, Bartenstein, P, de Toni, EN, Gasbarrini, A, Pech, M, Peck-Radosavljevic, M, Popovič, P, Rosmorduc, O, Schott, E, Seidensticker, M, Verslype, C, Sangro, B & Malfertheiner, P . Impact of combined selective internal radiation therapy and sorafenib on survival in advanced hepatocellular carcinoma. Journal of hepatology 2019;71:6:1164–1174 (Amsterdam UMC). 1207. Ried T, Meijer GA, Harrison DJ, Grech G, Franch-Exposito S, Briffa R, Carvalho B, Camps J. The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome. Mol Aspects Med 2019; 69:48-61 (NKI). 1208. Rigter LS, Rijkmans EC, Inderson A, van den Ende RP, Kerkhof EM, van Dieren J, Veenendaal RA, van Triest B, Marijnen CA, van der Heide UA, van Leerdam ME. EUS-guided fiducial marker placement for radiotherapy in rectal cancer: feasibility of two placement strategies and four fiducial types. Endosc Int Open 2019; 4:E378-E382 (NKI). 1209. Rigter, LS, Schaapveld, M, Janus, CPM, Krol, ADG, van der Maazen, RWM, Roesink, J, Zijlstra, JM, van Imhoff, GW, Poortmans, PMP, Beijert, M, Lugtenburg, PJ, Visser, O, Snaebjornsson, P, van Eggermond, AM, Aleman, BMP, van Leeuwen, FE & van Leerdam, ME . Overall and disease-specific survival of Hodgkin lymphoma survivors who subsequently developed gastrointestinal cancer. Cancer Medicine 2019;8:1:190-199 (Amsterdam UMC & NKI). 1210. Rigter, LS, Spaander, MCW, Aleman, BMP, Bisseling, TM, Moons, LM, Cats, A, Lugtenburg, PJ, Janus, CPM, Petersen, EJ, Roesink, JM, van der Maazen, RWM, Snaebjornsson, P, Kuipers, EJ, Bruno, MJ, Dekker, E, Meijer, GA, de Boer, JP, van Leeuwen, FE & van Leerdam, ME . High prevalence of advanced colorectal neoplasia and serrated polyposis syndrome in Hodgkin lymphoma survivors. Cancer 2019;125:6:990-999 (Amsterdam UMC & NKI). 1211. Rijken, JA, van Hulsteijn, LT, Dekkers, OM, Niemeijer, ND, Leemans, CR, Eijkelenkamp, K, van der Horst-Schrivers, ANA, Kerstens, MN, van Berkel, A, Timmers, HJLM, Kunst, H, Bisschop, PHLT, Dreijerink, KMA, van Dooren, MF, Hes, FJ, Jansen, JC, Corssmit, EPM & Hensen, EF . Increased mortality in SDHB but not in SDHD pathogenic variant carriers. Cancers (Basel) 2019;11:1: (Amsterdam UMC). 1212. Rijkmans EC, Marijnen CAM, van Triest B, Ketelaars M, Cats A, Inderson A, van den Ende RPJ, Laman MS, Kerkhof EM, Nout RA. Predictive factors for response and toxicity after brachytherapy for rectal cancer; results from the HERBERT study. Radiother Oncol 2019; 133:176-82 (NKI). 1213. Rikkert, LG, Nieuwland, R, Terstappen, LWMM & Coumans, FAW . Quality of extracellular vesicle images by transmission electron microscopy is operator and protocol dependent. Journal of extracellular vesicles 2019;8:1: (Amsterdam UMC). 1214. Ringborg U, Celis JE, Baumann M, Eggermont A, Wild CP, Berns A. Boosting the social impact of innovative cancer research - towards a mission-oriented approach to cancer. Mol Oncol 2019; 13:497-501 (NKI). 1215. Robert C, Grob JJ, Stroyakovskiy D, Karaszewska B, Hauschild A, Levchenko E, Chiarion S, V, Schachter J, Garbe C, Bondarenko I, Gogas H, Mandala M, Haanen JBAG, Lebbe C, Mackiewicz A, Rutkowski P, Nathan PD, Ribas A, Davies MA, Flaherty KT, Burgess P, Tan M, Gasal E, Voi M, Schadendorf D, Long GV. Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma. N Engl J Med 2019; 381:626-36 (NKI). 1216. Robert C, Ribas A, Schachter J, Arance A, Grob JJ, Mortier L, Daud A, Carlino MS, McNeil CM, Lotem M, Larkin JMG, Lorigan P, Neyns B, Blank CU, Petrella TM, Hamid O, Su SC, Krepler C, Ibrahim N, Long GV. Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study. Lancet Oncol 2019; 20:1239-51 (NKI). 1217. Rodrigues Neves, C, Buskermolen, J, Roffel, S, Waaijman, T, Thon, M, Veerman, E & Gibbs, S . Human saliva stimulates skin and oral wound healing in vitro. Journal of Tissue Engineering and Regenerative Medicine 2019;13:6:1079-1092 (Amsterdam UMC). 1218. Rodriguez, D, Chambers, T, Warmuth-Metz, M, Aliaga, ES, Warren, D, Calmon, R, Hargrave, D, Garcia, J, Vassal, G, Grill, J, Zahlmann, G, Morgan, PS & Jaspan, T . Evaluation of the Implementation of the Response Assessment in Neuro-Oncology Criteria in the HERBY Trial of Pediatric Patients with Newly Diagnosed High-Grade Gliomas. American Journal of Neuroradiology 2019;40:3:568-575 (Amsterdam UMC). 1219. Rogiers A, Boekhout A, Schwarze JK, Awada G, Blank CU, Neyns B. Long-Term Survival, Quality of Life, and Psychosocial Outcomes in Advanced Melanoma Patients Treated with Immune Checkpoint Inhibitors. J Oncol 2019; 2019:5269062 (17 pp) (NKI). 1220. Rohaan MW, Wilgenhof S, Haanen JBAG. Adoptive cellular therapies: the current landscape. Virchows Arch 2019; 474:449-61 (NKI). 1221. Rohde, GE, Young, T, Winstanley, J, Arraras, JI, Black, K, Boyle, F, Bredart, A, Costantini, A, Guo, J, Irarrazaval, ME, Kobayashi, K, Kruizinga, R, Navarro, M, Omidvari, S, Serpentini, S, Spry, N, van Laarhoven, H, Yang, G & Vivat, B . Associations between sex, age and spiritual well-being scores on the EORTC QLQ-SWB32 for patients receiving palliative care for cancer: A further analysis of data from an international validation study. European journal of cancer care 2019 (Amsterdam UMC). 1222. Rolfo C, de Vos-Geelen J, Isambert N, Molife LR, Schellens JHM, De Greve J, Dirix L, Grundtvig- Sorensen P, Jerusalem G, Leunen K, Mau-Sorensen M, Plummer R, Learoyd M, Bannister W, Fielding A, Ravaud A. Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment. Clin Pharmacokinet 2019; 58:1165-74 (NKI). 1223. Romagnoli M, Cagnet S, Chiche A, Bresson L, Baulande S, de la Grange P, De Arcangelis A, Kreft M, George-Labouesse E, Sonnenberg A, Deugnier MA, Raymond K, Glukhova MA, Faraldo MM. Deciphering the Mammary Stem Cell Niche: A Role for Laminin-Binding Integrins. Stem Cell Reports 2019; 12:831-44 (NKI). 1224. Rontogianni S, Synadaki E, Li B, Liefaard MC, Lips EH, Wesseling J, Wu W, Altelaar M. Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping. Commun Biol 2019; 2:325 (NKI). 1225. Roodbeen, S, lo Conte, A, Allison, H, Penna, M, Bemelman, W, Tanis, P & Hompes, R . Evolution of transanal total mesorectal excision according to the IDEAL framework. BMJ Surgery, Interventions, & Health Technologies 2019;1:: (Amsterdam UMC). 1226. Roodbeen, SX, Penna, M, Arnold, S, Wynn, G, Warüsavitarne, J, Francis, N, Moran, B & Hompes, R . A nationwide study on the adoption and short-term outcomes of transanal total mesorectal excision in the UK. Minerva chirurgica 2019;74:4:279-288 (Amsterdam UMC). 1227. Roorda JC, Joosten RP, Perrakis A, Hiruma Y. A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop. Proteins 2019; 87:348-52 (NKI). 1228. Roos VH, Mangas-Sanjuan C, Rodriguez-Girondo M, Prado LM, Steyerberg EW, Bossuyt PMM, Dekker E, Jover R, van Leerdam ME. Effects of Family History on Relative and Absolute Risks for Colorectal Cancer: a Systematic Review and Meta-Analysis. Clin Gastroenterol Hepatol 2019; 17:2657-67 (NKI). 1229. Roos, E, Franken, LC, Soer, EC, van Hooft, JE, Takkenberg, RB, Klümpen, H-J, Wilmink, JW, van de Vijver, MJ, van Gulik, TM & Verheij, J . Lost in translation: confusion on resection and dissection planes hampers the interpretation of pathology reports for perihilar cholangiocarcinoma. Virchows Archiv 2019;475:4:435-443 (Amsterdam UMC). 1230. Roos, E, Soer, EC, Klompmaker, S, Meijer, LL, Besselink, MG, Giovannetti, E, Heger, M, Kazemier, G, Klümpen, HJ, Takkenberg, RB, Wilmink, H, Würdinger, T, Dijk, F, van Gulik, TM, Verheij, J & van de Vijver, MJ . Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract. Critical reviews in oncology/hematology 2019;140::8-16. (Amsterdam UMC). 1231. Roos, VH, Bastiaansen, BAJ & Dekker, E . Challenges and pitfalls of investigating duodenal cancer in patients with familial adenomatous polyposis. Gastrointestinal endoscopy 2019;89:2:355-356 (Amsterdam UMC). 1232. Roosendaal J, Rosing H, Lucas L, Oganesian A, Schellens JHM, Beijnen JH. Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantification of total intracellular beta-decitabine nucleotides and genomic DNA incorporated beta-decitabine and 5-methyl-2'-deoxycytidine. J Pharm Biomed Anal 2019; 164:16-26 (NKI). 1233. Roosendaal J, Wang K, Rosing H, Lucas L, Gebretensae A, Oganesian A, Schellens JHM, Beijnen JH, Lin ZJ. Development and validation of LC-MS/MS methods for the quantification of the novel anticancer agent guadecitabine and its active metabolite betadecitabine in human plasma, whole blood and urine. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1109:132-41 (NKI). 1234. Rosenwald, A, Bens, S, Advani, R, Barrans, S, Copie-Bergman, C, Elsensohn, M-H, Natkunam, Y, Calaminici, M, Sander, B, Baia, M, Smith, A, Painter, D, Pham, L, Zhao, S, Ziepert, M, Jordanova, ES, Molina, TJ, Kersten, MJ, Kimby, E, Klapper, W, Raemaekers, J, Schmitz, N, Jardin, F, Stevens, WBC, Hoster, E, Hagenbeek, A, Gribben, JG, Siebert, R, Gascoyne, RD, Scott, DW, Gaulard, P, Salles, G, Burton, C, de Jong, D, Sehn, LH & Maucort-Boulch, D . Prognostic significance of MYC rearrangement and translocation partner in diffuse large B-cell lymphoma: A study by the Lunenburg Lymphoma Biomarker Consortium. Journal of clinical oncology 2019;37:35:3359-3368 (Amsterdam UMC). 1235. Rosmolen, WD, Phoa, NKYN, Nieuwkerk, PT, Pouw, RE, Weusten, BLAM, Bisschops, R, Schoon, EJ, Sprangers, MAG & Bergman, JJGHM . Impact of ablation of Barrett's esophagus with low-grade dysplasia on patients’ illness perception and quality of life: a multicenter randomized trial. Gastrointestinal endoscopy 2019;90:2:215-221 (Amsterdam UMC). 1236. Rösner, T, Kahle, S, Montenegro, F, Matlung, HL, Jansen, JHM, Evers, M, Beurskens, F, Leusen, JHW, van den Berg, TK & Valerius, T . Immune Effector Functions of Human IgG2 Antibodies against EGFR. Molecular cancer therapeutics 2019;18:1:75-88 (Amsterdam UMC). 1237. Rotman, J, Koster, BD, Jordanova, ES, Heeren, AM & de Gruijl, TD . Unlocking the therapeutic potential of primary tumor-draining lymph nodes. Cancer Immunology and Immunotherapy 2019;68:10:1681-1688 (Amsterdam UMC). 1238. Rotoli, D, Morales, M, Maeso, M-D-C, Ávila, J, Pérez-Rodríguez, ND, Mobasheri, A, van Noorden, CJF & Martín-Vasallo, P . IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. journal of histochemistry and cytochemistry 2019;67:7:481-494 (Amsterdam UMC). 1239. Rottenberg, Y, Amir, Z & De Boer, AGEM . Work cessation after cancer diagnosis. Occupational medicine (Oxford, England) 2019;69:2:126-132 (Amsterdam UMC). 1240. Rotteveel, L, Poot, AJ, Bogaard, HJ, ten Dijke, P, Lammertsma, AA & Windhorst, AD . In vivo imaging of TGFβ signalling components using positron emission tomography. Drug Discovery Today 2019;24:12:2258-2272 (Amsterdam UMC). 1241. Rovers KP, Lurvink RJ, Wassenaar EC, Kootstra TJ, Scholten HJ, Tajzai R, Deenen MJ, Nederend J, Lahaye MJ, Huysentruyt CJ, van 't Erve I, Fijneman RJ, Constantinides A, Kranenburg O, Los M, Thijs AM, Creemers GM, Burger JW, Wiezer MJ, Boerma D, Nienhuijs SW, de Hingh I. Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC). BMJ Open 2019; 9:e030408 (NKI). 1242. Rovers, KP, Bakkers, C, Simkens, GAAM, Burger, JWA, Nienhuijs, SW, Creemers, G-JM, Thijs, AMJ, Brandt-Kerkhof, ARM, Madsen, EVE, Ayez, N, de Boer, NL, van Meerten, E, Tuynman, JB, Kusters, M, Sluiter, NR, Verheul, HMW, van der Vliet, HJ, Wiezer, MJ, Boerma, D, Wassenaar, ECE, Los, M, Hunting, CB, Aalbers, AGJ, Kok, NFM, Kuhlmann, KFD, Boot, H, Chalabi, M, Kruijff, S, Been, LB, van Ginkel, RJ, de Groot, DJA, Fehrmann, RSN, de Wilt, JHW, Bremers, AJA, de Reuver, PR, Radema, SA, Herbschleb, KH, van Grevenstein, WMU, Witkamp, AJ, Koopman, M, Haj Mohammad, N, van Duyn, EB, Mastboom, WJB, Mekenkamp, LJM, Nederend, J, Lahaye, MJ, Snaebjornsson, P, Verhoef, C, van Laarhoven, HWM, Zwinderman, AH, Bouma, JM, Kranenburg, O, van . Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: Protocol of a multicentre, open-label, parralel- group, phase II-III, randomised, superiority study (CAIRO6). BMC cancer 2019;19:1: (Amsterdam UMC & NKI). 1243. Rovithi, M, Gerritse, SL, Honeywell, RJ, Ten Tije, AJ, Ruijter, R, Peters, GJ, Voortman, J, Labots, M & Verheul, HMW . Phase I Dose-Escalation Study of Once Weekly or Once Every Two Weeks Administration of High-Dose Sunitinib in Patients With Refractory Solid Tumors. Journal of Clinical Oncology 2019;37:5:411-418 (Amsterdam UMC). 1244. Rozeman EA, Blank CU. Combining checkpoint inhibition and targeted therapy in melanoma. Nat Med 2019; 25:879-82 (NKI). 1245. Rozeman EA, Menzies AM, van Akkooi ACJ, Adhikari C, Bierman C, van de Wiel BA, Scolyer RA, Krijgsman O, Sikorska K, Eriksson H, Broeks A, van Thienen JV, Guminski AD, Acosta AT, Ter Meulen S, Koenen AM, Bosch LJW, Shannon K, Pronk LM, Gonzalez M, Ch'ng S, Grijpink-Ongering LG, Stretch J, Heijmink S, Van Tinteren H, Haanen JBAG, Nieweg OE, Klop WMC, Zuur CL, Saw RPM, van Houdt WJ, Peeper DS, Spillane AJ, Hansson J, Schumacher TN, Long GV, Blank CU. Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial. Lancet Oncol 2019; 20:948-60 (NKI). 1246. Rubello D, Tartaglione G, Valdes Olmos R, Giammarile F. Letter to the editor-in-chief of Head and Neck. Head Neck 2019; 41:4234-5 (NKI). 1247. Ruchlemer, R, Ben-Ami, R, Bar-Meir, M, Brown, JR, Malphettes, M, Mous, R, Tonino, SH, Soussain, C, Barzic, N, Messina, JA, Jain, P, Cohen, R, Hill, B, Mulligan, SP, Nijland, M, Herishanu, Y, Benjamini, O, Tadmor, T, Okamoto, K, Arthurs, B, Gottesman, B, Kater, AP, Talha, M, Eichhorst, B, Korem, M, Bogot, N, de Boer, F, Rowe, JM & Lachish, T . Ibrutinib-associated invasive fungal diseases in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: An observational study. Mycoses 2019;62:12:1140-1147 (Amsterdam UMC). 1248. Rudra, S, Jiang, N, Rosenberg, SA, Olsen, JR, Roach, MC, Wan, L, Portelance, L, Mellon, EA, Bruynzeel, A, Lagerwaard, F, Bassetti, MF, Parikh, PJ & Lee, PP . Using adaptive magnetic resonance image- guided radiation therapy for treatment of inoperable pancreatic cancer. Cancer Medicine 2019;8:5:2123-2132 (Amsterdam UMC). 1249. Ruers TJM. The future of surgical oncology. Br J Surg 2019; 106:663-4 (NKI). 1250. Rutgers E, Balmana J, Beishon M, Benn K, Evans DG, Mansel R, Pharoah P, Perry S, V, Stoppa-Lyonnet D, Travado L, Wyld L. European Breast Cancer Council manifesto 2018: Genetic risk prediction testing in breast cancer. Eur J Cancer 2019; 106:45-53 (NKI). 1251. Rutgers EJT. Is prophylactic mastectomy justified in women without BRCA mutation? Breast 2019; 48 Suppl 1:S62-S64 . (NKI). 1252. Saadani, H, Van der Hiel, B, Aalbersberg, EA, Zavrakidis, I, Haanen, JBAG, Hoekstra, OS, Boellaard, R & Stokkel, MPM . Metabolic biomarker–based BRAFV600 mutation association and prediction in melanoma. Journal of Nuclear Medicine 2019;60:11:1545-1552 (Amsterdam UMC & NKI). 1253. Saadatmand S, Geuzinge HA, Rutgers EJT, Mann RM, de Roy van Zuidewijn DBW, Zonderland HM, Tollenaar RAEM, Lobbes MBI, Ausems MGEM, van 't Riet M, Hooning MJ, Mares-Engelberts I, Luiten EJT, Heijnsdijk EAM, Verhoef C, Karssemeijer N, Oosterwijk JC, Obdeijn IM, de Koning HJ, Tilanus- Linthorst MMA. MRI versus mammography for breast cancer screening in women with familial risk (FaMRIsc): a multicentre, randomised, controlled trial. Lancet Oncol 2019; 20:1136-47 (NKI). 1254. Sabrkhany, S, Kuijpers, MJE, Griffioen, AW & Oude Egbrink, MGA . Platelets. Angiogenesis 2019;22:1: (Amsterdam UMC). 1255. Sachs N, Papaspyropoulos A, Zomer-van Ommen DD, Heo I, Bottinger L, Klay D, Weeber F, Huelsz- Prince G, Iakobachvili N, Amatngalim GD, de Ligt J, van Hoeck A, Proost N, Viveen MC, Lyubimova A, Teeven L, Derakhshan S, Korving J, Begthel H, Dekkers JF, Kumawat K, Ramos E, van Oosterhout MF, Offerhaus GJ, Wiener DJ, Olimpio EP, Dijkstra KK, Smit EF, van der Linden M, Jaksani S, van de Ven M, Jonkers J, Rios AC, Voest EE, van Moorsel CH, van der Ent CK, Cuppen E, van Oudenaarden A, Coenjaerts FE, Meyaard L, Bont LJ, Peters PJ, Tans SJ, van Zon JS, Boj SF, Vries RG, Beekman JM, Clevers H. Long-term expanding human airway organoids for disease modeling. EMBO J 2019; 38:e100300 (20 pp) (NKI). 1256. Sahasrabudhe, NM, van der Horst, JC, Spaans, V, Kenter, G, de Kroon, C, Bosse, T, van Vliet, SJ & Jordanova, ES . MGL ligand expression is correlated to lower survival and distant metastasis in cervical squamous cell and adenosquamous carcinoma. Frontiers in Oncology 2019;9:: (Amsterdam UMC). 1257. Saleem, H, Kulsoom Abdul, U, Küçükosmanoglu, A, Houweling, M, Cornelissen, FMG, Heiland, DH, Hegi, ME, Kouwenhoven, MCM, Bailey, D, Würdinger, T & Westerman, BA . The TICking clock of EGFR therapy resistance in glioblastoma. Drug Resistance Updates 2019;43::29-37. (Amsterdam UMC). 1258. Salerno, F, Guislain, A, Freen-van Heeren, JJ, Nicolet, BP, Young, HA & Wolkers, MC . Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells. Oncoimmunology 2019;8:2: (Amsterdam UMC). 1259. Salgado C, Kwesi-Maliepaard EM, Jochemsen AG, Visser M, Harland M, van Leeuwen F, van Doorn R, Gruis N. A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma. Melanoma Res 2019; 29:582-9 (NKI). 1260. Salgado R, Solit DB, Rimm DL, Bogaerts J, Canetta R, Lively T, Lyerly K, Span PN, Bateman-House A, Makady A, Bergmann L, Nagai S, Smith C, Robson M, Savage M, Voest E, Sweeney C, Lambin P, Thomas M, Harris L, Lacombe D, Massard C. Addressing the dichotomy between individual and societal approaches to personalised medicine in oncology. Eur J Cancer 2019; 114:128-36 (NKI). 1261. Salgado-Polo F, Perrakis A. The Structural Binding Mode of the Four Autotaxin Inhibitor Types that Differentially Affect Catalytic and Non-Catalytic Functions. Cancers (Basel) 2019; 11:1577 (17 pp) (NKI). 1262. Salvagno C, Ciampricotti M, Tuit S, Hau CS, van Weverwijk A, Coffelt SB, Kersten K, Vrijland K, Kos K, Ulas T, Song JY, Ooi CH, Ruttinger D, Cassier PA, Jonkers J, Schultze JL, Ries CH, de Visser KE. Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nat Cell Biol 2019; 21:511-21 (NKI). 1263. Samsom KG, van Veenendaal LM, Valk GD, Vriens MR, Tesselaar M, van den Berg JG. Molecular prognostic factors in small-intestinal neuro-endocrine tumours. Endocr Connect 2019; 8:906-22 (NKI). 1264. Sanchez IM, Purwin TJ, Chervoneva I, Erkes DA, Nguyen MQ, Davies MA, Nathanson KL, Kemper K, Peeper DS, Aplin AE. In vivo ERK1/2 reporter predictively models response and resistance to combined BRAF and MEK inhibitors in melanoma. Mol Cancer Ther 2019; 18:1627-48 (NKI). 1265. Sánchez-Querubín, N & van Laarhoven, HWM . Vlogging at the end of life. lancet oncology 2019;20:7:911-912 (Amsterdam UMC). 1266. Sanchez-Spitman A, Dezentje V, Swen J, Moes DJAR, Bohringer S, Batman E, van Druten E, Smorenburg C, van Bochove A, Zeillemaker A, Jongen L, Los M, Neven P, Gelderblom H, Guchelaar HJ. Tamoxifen Pharmacogenetics and Metabolism: Results From the Prospective CYPTAM Study. J Clin Oncol 2019; 37:636-46 (NKI). 1267. Sanchez-Spitman AB, Swen JJ, Dezentje VO, Moes DJAR, Gelderblom H, Guchelaar HJ. Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen. Expert Rev Clin Pharmacol 2019; 12:523-36 (NKI). 1268. Sánchez-Velázquez, P, Muller, X, Malleo, G, Park, J-S, Hwang, H-K, Napoli, N, Javed, AA, Inoue, Y, Beghdadi, N, Kalisvaart, M, Vigia, E, Walsh, CD, Lovasik, B, Busquets, J, Scandavini, C, Robin, F, Yoshitomi, H, Mackay, TM, Busch, OR, Hartog, H, Heinrich, S, Gleisner, A, Perinel, J, Passeri, M, Lluis, N, Raptis, DA, Tschuor, C, Oberkofler, CE, DeOliveira, ML, Petrowsky, H, Martinie, J, Asbun, H, Adham, M, Schulick, R, Lang, H, Koerkamp, BG, Besselink, MG, Han, H-S, Miyazaki, M, Ferrone, CR, Fernández-del Castillo, C, Lillemoe, KD, Sulpice, L, Boudjema, K, del Chiaro, M, Fabregat, J, Kooby, DA, Allen, P, Lavu, H, Yeo, CJ, Barroso, E, Roberts, K, Muiesan, P, Sauvanet, A, Saiura, A, Wolfgang, CL, Cameron, JL, Boggi, U, Yoon, D-S, Bassi, C, Puhan, MA & Clavien, P-A . Benchmarks in Pancreatic Surgery: A Novel Tool for Unbiased Outcome Comparisons. Annals of surgery 2019;270:2:211-218 (Amsterdam UMC). 1269. Sandberg, TP, Sweere, I, van Pelt, GW, Putter, H, Vermeulen, L, Kuppen, PJ, Tollenaar, RAEM & Mesker, WE . Prognostic value of low CDX2 expression in colorectal cancers with a high stromal content – a short report. Cellular oncology 2019 (Amsterdam UMC). 1270. Sandbergen, L, Guven, S & Laguna, MP . Can ablation win against partial nephrectomy and become first line therapy in cT1a renal tumours?. Current opinion in urology 2019;29:1:70-77 (Amsterdam UMC). 1271. Sandbergen, L, Spriensma, AS, de la Rosette, JJ & Laguna, MP . Health-related quality of life in localized renal masses: A matter of sparing nephrons or minimizing the incision?. Urologic oncology 2019 (Amsterdam UMC). 1272. Sanghvi VR, Leibold J, Mina M, Mohan P, Berishaj M, Li Z, Miele MM, Lailler N, Zhao C, de Stanchina E, Viale A, Akkari L, Lowe SW, Ciriello G, Hendrickson RC, Wendel HG. The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase. Cell 2019; 178:807-19 (NKI). 1273. Santegoets, KCM, Gielen, PR, Büll, C, Schulte, BM, Kers-Rebel, ED, Küsters, B, Bossman, SAJFH, ter Laan, M, Wesseling, P & Adema, GJ . Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma. Cancer Immunology and Immunotherapy 2019;68:6:937-949 (Amsterdam UMC). 1274. Santegoets, SJ, Duurland, CL, Jordanova, ES, van Ham, JJ, Ehsan, I, van Egmond, SL, Welters, MJP & van der Burg, SH . Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses. Journal for Immunotherapy of Cancer 2019;7:1:14 (Amsterdam UMC). 1275. Santini, V & Ossenkoppele, GJ . Hypomethylating agents in the treatment of acute myeloid leukemia: A guide to optimal use. Critical Reviews in Oncology / Hematology 2019;140::44013 (Amsterdam UMC). 1276. Santoso, AMM, Jansen, F, de Vries, R, Leemans, CR, van Straten, A & Verdonck-de Leeuw, IM . Prevalence of sleep disturbances among head and neck cancer patients: A systematic review and meta-analysis. Sleep Medicine Reviews 2019;47::62-73 (Amsterdam UMC). 1277. Sapmaz A, Berlin I, Bos E, Wijdeven RH, Janssen H, Konietzny R, Akkermans JJ, Erson-Bensan AE, Koning RI, Kessler BM, Neefjes J, Ovaa H. USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7. Nat Commun 2019; 10:1454 (NKI). 1278. Sassen, SDT, Zwaan, CM, van der Sluis, IM & Mathôt, RAA . Pharmacokinetics and population pharmacokinetics in pediatric oncology. Pediatric blood & cancer 2019 (Amsterdam UMC). 1279. Savci-Heijink, CD, Halfwerk, H, Hooijer, GKJ, Koster, J, Horlings, HM, Meijer, SL & van de Vijver, MJ . Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior. Breast cancer research and treatment 2019;174:3:649-659 (Amsterdam UMC & NKI). 1280. Savci-Heijink, CD, Halfwerk, H, Koster, J, Horlings, HM & van de Vijver, MJ . A specific gene expression signature for visceral organ metastasis in breast cancer. BMC cancer 2019;19:1: (Amsterdam UMC & NKI). 1281. Schadendorf D, Ascierto PA, Haanen J, Espinosa E, Demidov L, Garbe C, Guida M, Lorigan P, Chiarion- Sileni V, Gogas H, Maio M, Fierro MT, Hoeller C, Terheyden P, Gutzmer R, Guren TK, Bafaloukos D, Rutkowski P, Plummer R, Waterston A, Kaatz M, Mandala M, Marquez-Rodas I, Munoz-Couselo E, Dummer R, Grigoryeva E, Young TC, Nathan P. Safety and efficacy of nivolumab in challenging subgroups with advanced melanoma who progressed on or after ipilimumab treatment: A single- arm, open-label, phase II study (CheckMate 172). Eur J Cancer 2019; 121:144-53 (NKI). 1282. Scheffer, HJ, Stam, AGM, Geboers, B, Vroomen, LGPH, Ruarus, A, de Bruijn, B, van den Tol, MP, Kazemier, G, Meijerink, MR & de Gruijl, TD . Irreversible electroporation of locally advanced pancreatic cancer transiently alleviates immune suppression and creates a window for antitumor T cell activation. OncoImmunology 2019;8:11: (Amsterdam UMC). 1283. Scheltema, MJ, Chang, JI, Stricker, PD, van Leeuwen, PJ, Nguyen, QA, Ho, B, Delprado, W, Lee, J, Thompson, JE, Cusick, T, Spriensma, AS, Siriwardana, AR, Yuen, C, Kooner, R, Hruby, G, O. Diagnostic accuracy of 68Ga-prostate-specific membrane antigen (PSMA) positron-emission tomography (PET) and multiparametric (mp)MRI to detect intermediate-grade intra-prostatic prostate cancer using whole-mount pathology: impact of the addition of 68Ga-PSMA PET to mpMRI. BJU international 2019;124:S1:42-49 (Amsterdam UMC). 1284. Scheltema, MJ, O. Numerical simulation modeling of the irreversible electroporation treatment zone for focal therapy of prostate cancer, correlation with whole-mount pathology and T2-weighted MRI sequences. Therapeutic advances in urology 2019;11::1756287219852305. (Amsterdam UMC). 1285. Scheper, W, Kelderman, S, Fanchi, LF, Linnemann, C, Bendle, G, de Rooij, MAJ, Hirt, C, Mezzadra, R, Slagter, M, Dijkstra, K, Kluin, RJC, Snaebjornsson, P, Milne, K, Nelson, BH, Zijlmans, H, Kenter, G, Voest, EE, Haanen, JBAG & Schumacher, TN . Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers. Nature medicine 2019;25:1:89-94 (Amsterdam UMC & NKI). 1286. Schermers B, Franke V, Rozeman EA, van de Wiel BA, Bruining A, Wouters MW, van Houdt WJ, Ten Haken B, Muller SH, Bierman C, Ruers TJM, Blank CU, van Akkooi ACJ. Surgical removal of the index node marked using magnetic seed localization to assess response to neoadjuvant immunotherapy in patients with stage III melanoma. Br J Surg 2019; 106:519-22 (NKI). 1287. Schetters, STT, Jong, WSP, Horrevorts, SK, Kruijssen, LJW, Engels, S, Stolk, D, Daleke-Schermerhorn, MH, Garcia-Vallejo, J, Houben, D, Unger, WWJ, den Haan, JMM, Luirink, J & van Kooyk, Y . Outer membrane vesicles engineered to express membrane-bound antigen program dendritic cells for cross-presentation to CD8+ T cells. Acta Biomaterialia 2019 (Amsterdam UMC). 1288. Schilling B, Martens A, Geukes Foppen MH, Gebhardt C, Hassel JC, Rozeman EA, Gesierich A, Gutzmer R, Kahler KC, Livingstone E, Diamantopoulos PT, Gogas H, Madonna G, Ascierto PA, Goldinger SM, Mangana J, Garbe C, Schadendorf D, Blank C, Weide B. First-line therapy-stratified survival in BRAF-mutant melanoma: a retrospective multicenter analysis. Cancer Immunol Immunother 2019; 68:765-72 (NKI). 1289. Schilling C, Stoeckli SJ, Vigili MG, De Bree R, Lai SY, Alvarez J, Christensen A, Cognetti DM, D'Cruz AK, Frerich B, Garrel R, Kohno N, Klop M, Kerawala C, Lawson G, McMahon J, Sassoon I, Shaw RJ, Tvedskov JF, von Buchwald C, McGurk M. Surgical consensus guidelines on sentinel node biopsy (SNB) in patients with oral cancer. Head Neck 2019; 41:2655-64 (NKI). 1290. Schipper K, Seinstra D, Drenth AP, van der Burg E, Ramovs V, Sonnenberg A, van Rheenen J, Nethe M, Jonkers J. Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin. Nat Commun 2019; 10:3800 (NKI). 1291. Schmidlin T, Debets DO, van Gelder CAGH, Stecker KE, Rontogianni S, van den Eshof BL, Kemper K, Lips EH, van den Biggelaar M, Peeper DS, Heck AJR, Altelaar M. High-Throughput Assessment of Kinome-wide Activation States. Cell Syst 2019; 9:366-74(NKI). 1292. Schmitz KH, Campbell AM, Stuiver MM, Pinto BM, Schwartz AL, Morris GS, Ligibel JA, Cheville A, Galvao DA, Alfano CM, Patel AV, Hue T, Gerber LH, Sallis R, Gusani NJ, Stout NL, Chan L, Flowers F, Doyle C, Helmrich S, Bain W, Sokolof J, Winters-Stone KM, Campbell KL, Matthews CE. Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer. CA Cancer J Clin 2019; 69:468-84 (NKI). 1293. Schokker, S, van der Woude, SO, van Kleef, JJ, van Zoen, DJ, van Oijen, MGH, Mearadji, B, Beenen, LFM, Stroes, CI, Waasdorp, C, Jibodh, RA, Creemers, A, Meijer, SL, Hooijer, GKJ, Punt, CJA, Bijlsma, MF & van Laarhoven, HWM . Phase I Dose escalation study with expansion cohort of the addition of nab-paclitaxel to capecitabine and oxaliplatin (CapOx) as first-line treatment of metastatic esophagogastric adenocarcinoma (ACTION study). Cancers 2019;11:6: (Amsterdam UMC). 1294. Scholl, S, Popovic, M, de la Rochefordiere, A, Girard, E, Dureau, S, Mandic, A, Koprivsek, K, Samet, N, Craina, M, Margan, M, Samuels, S, Zijlmans, H, Kenter, G, Hillemanns, P, Dema, S, Dema, A, Malenkovic, G, Djuran, B, Floquet, A, Garbay, D, Guyon, F, Colombo, PE, Fabbro, M, Kerr, C, Ngo, C, Lecuru, F, Campo, ERD, Coutant, C, Marchal, F, Mesgouez-Nebout, N, Fourchotte, V, Feron, JG, Morice, P, Deutsch, E, Wimberger, P, Classe, J-M, Gleeson, N, von der Leyen, H, Minsat, M, Dubot, C, Gestraud, P, Kereszt, A, Nagy, I, Balint, B, Berns, E, Jordanova, E, Saint-Jorre, ND, Savignoni, A, Servant, N, Hupe, P, de Koning, L, Fumoleau, P, Rouzier, R & Kamal, M . Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome. EBioMedicine 2019;43::253-260. (Amsterdam UMC & NKI). 1295. Schooneveldt, G, Trefná, HD, Persson, M, de Reijke, T, Blomgren, K, Kok, P & Crezee, H . Hyperthermia treatment planning including convective flow in cerebrospinal fluid for brain tumour hyperthermia treatment using a novel dedicated paediatric brain applicator. Cancers 2019;11:8: (Amsterdam UMC). 1296. Schoormans D, Husson O, Oerlemans S, Ezendam N, Mols F. Having co-morbid cardiovascular disease at time of cancer diagnosis: already one step behind when it comes to HRQoL? Acta Oncol 2019; 58:1684-91 . (NKI). 1297. Schouten, SM, van de Velde, ME, Kaspers, GJL, Mokkink, LB, van der Sluis, IM, van den Bos, C, Hartman, A, Abbink, FCH & van den Berg, MH . Measuring vincristine-induced peripheral neuropathy in children with cancer: validation of the Dutch pediatric–modified Total Neuropathy Score. Supportive care in cancer 2019 (Amsterdam UMC). 1298. Schouwenburg, MG, Suijkerbuijk, KPM, Koornstra, RHT, Jochems, A, van Zeijl, MCT, van den Eertwegh, AJM, Haanen, JBAG, Aarts, MJ, van Akkooi, ACJ, van den Berkmortel, FWPJ, de Groot, JWB, Hospers, GAP, Kapiteijn, E, Kruit, WH, Piersma, D, van Rijn, RS, ten Tije, AJ, Vreugdenhil, G, van der Hoeven, JJM & Wouters, MWJM . Switching to immune checkpoint inhibitors upon response to targeted therapy; the road to long- term survival in advanced melanoma patients with highly elevated serum LDH?. Cancers (Basel) 2019;11:12: (Amsterdam UMC & NKI). 1299. Schreuder, AM, Engelsman, AF, van Roessel, S, Verheij, J, Besselink, MG, van Gulik, TM & Busch, OR . Treatment of mid-bile duct carcinoma: Local resection or pancreatoduodenectomy?. European journal of surgical oncology 2019 (Amsterdam UMC). 1300. Schreuder, AM, Eskes, AM, van Langen, RGM, van Dieren, S & Nieveen van Dijkum, EJM . Active involvement of family members in postoperative care after esophageal or pancreatic resection: A feasibility study. Surgery 2019 (Amsterdam UMC). 1301. Schreuder, K, Maduro, JH, Spronk, PER, Bijker, N, Poortmans, PMP, van Dalen, T, Struikmans, H & Siesling, S . Variation in the Use of Boost Irradiation in Breast-Conserving Therapy in the Netherlands: The Effect of a National Guideline and Cofounding Factors. Clinical oncology (Royal College of Radiologists (Great Britain)) 2019;31:4:250-259 (Amsterdam UMC). 1302. Schröder, W, Raptis, DA, Schmidt, HM, Gisbertz, SS, Moons, J, Asti, E, Luyer, MDP, Hölscher, AH, Schneider, PM, Henegouwen, MIVB, Nafteux, P, Nilsson, M, Räsanen, J, Palazzo, F, Mercer, S, Bonavina, L, Nieuwenhuijzen, GAP, Wijjnhoven, BPL, Pattyn, P, Grimminger, PP, Bruns, CJ & Gutschow, CA . Anastomotic Techniques and Associated Morbidity in Total Minimally Invasive Transthoracic Esophagectomy: Results from the EsoBenchmark Database. Annals of surgery 2019 (Amsterdam UMC). 1303. Schuit, AS, Holtmaat, K, Hooghiemstra, N, Jansen, F, Lissenberg-Witte, BI, Coupé, VMH, Van Linde, ME, Becker-Commissaris, A, Reijneveld, JC, Zijlstra, JM, Sommeijer, DW, Eerenstein, SEJ & Verdonck- De Leeuw, IM . Efficacy and cost-utility of the eHealth application 'Oncokompas', supporting patients with incurable cancer in finding optimal palliative care, tailored to their quality of life and personal preferences. BMC Palliative Care 2019;18:1: (Amsterdam UMC). 1304. Schumacher TN, Scheper W, Kvistborg P. Cancer Neoantigens. Annu Rev Immunol 2019; 37:173-200 (NKI). 1305. Schurink NW, Lambregts DMJ, Beets-Tan RGH. Diffusion-weighted imaging in rectal cancer: current applications and future perspectives. Br J Radiol 2019; 92:20180655 (NKI). 1306. Schutz K, Alecsandru D, Grimbacher B, Haddock J, Bruining A, Driessen G, de Vries E, van Hagen PM, Hartmann I, Fraioli F, Milito C, Mitrevski M, Quinti I, Serra G, Kelleher P, Loebinger M, Litzman J, Postranecka V, Thon V, Babar J, Condliffe AM, Exley A, Kumararatne D, Screaton N, Jones A, Bondioni MP, Lougaris V, Plebani A, Soresina A, Sirignano C, Spadaro G, Galal N, Gonzalez-Granado LI, Dettmer S, Stirling R, Chapel H, Lucas M, Patel S, Farber CM, Meyts I, Banerjee AK, Hackett S, Hurst JR, Warnatz K, Gathmann B, Baumann U. Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group. J Clin Immunol 2019; 39:45-54 (NKI). 1307. Schuurhuizen, CSEW, Braamse, AMJ, Beekman, ATF, Cuijpers, P, van der Linden, MHM, Hoogendoorn, AW, Berkhof, H, Sommeijer, DW, Lustig, V, Vrijaldenhoven, S, Bloemendal, HJ, van Groeningen, CJ, van Zweeden, AA, van der Vorst, MJDL, Rietbroek, R, Tromp-van Driel, CS, Wymenga, MNW, van der Linden, PW, Beeker, A, Polee, MB, Batman, E, Los, M, van Bochove, A, Brakenhoff, JAC, Konings, IRHM, Verheul, HMW & Dekker, J . Screening and stepped care targeting psychological distress in patients with metastatic colorectal cancer: The TES cluster randomized trial. Journal of the national comprehensive cancer network 2019;17:8:911-920 (Amsterdam UMC). 1308. Schuurhuizen, CSEW, Braamse, AMJ, Konings, IRHM, Verheul, HMW & Dekker, J . Predictors for use of psychosocial services in patients with metastatic colorectal cancer receiving first line systemic treatment. BMC Cancer 2019;19:1: (Amsterdam UMC). 1309. Schuurman, TN, Witteveen, PO, van der Wall, E, Passier, JLM, Huitema, ADR, Amant, F & Lok, CAR . Tamoxifen and pregnancy: an absolute contraindication?. Breast cancer research and treatment 2019;175:1:17-25 (Amsterdam UMC & NKI). 1310. Sciarrillo, R, Wojtuszkiewicz, A, El Hassouni, B, Funel, N, Gandellini, P, Lagerweij, T, Buonamici, S, Blijlevens, M, Zeeuw van der Laan, EA, Zaffaroni, N, Deraco, M, Kusamura, S, Würdinger, T, Peters, GJ, Molthoff, CFM, Jansen, G, Kaspers, GJL, Cloos, J & Giovannetti, E . Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma. EBioMedicine 2019;39::215-225. (Amsterdam UMC). 1311. Sedeno Cacciatore A, Rowland BD. Loop formation by SMC complexes: turning heads, bending elbows, and fixed anchors. Curr Opin Genet Dev 2019; 55:11-8 (NKI). 1312. Seiler R, Gibb EA, Wang NQ, Oo HZ, Lam HM, Van Kessel KE, Voskuilen CS, Winters B, Erho NG, Takhar MM, Douglas J, Vakar-Lopez F, Crabb SJ, van Rhijn BWG, Fransen van de Putte EE, Zwarthoff EC, Thalmann GN, Davicioni E, Boormans JL, Dall'Era M, van der Heijden MS, Wright JL, Black PC. Divergent biological response to neoadjuvant chemotherapy in muscle-invasive bladder cancer. Clin Cancer Res 2019; 25:5082-93 (NKI). 1313. Selvakumar, T, Nies, M, Klein Hesselink, MS, Brouwers, AH, Van Der Horst-Schrivers, ANA, Klein Hesselink, EN, Tissing, WJE, Vissink, A, Links, TP & Dutch Pediatric Thyroid Cancer Study Consortium . Long-term effects of radioiodine treatment on salivary gland function in adult survivors of pediatric differentiated thyroid carcinoma. Journal of Nuclear Medicine 2019;60:2:172-177 (Amsterdam UMC). 1314. Selvaraj J, Lebesque J, Hope A, Guckenberger M, Werner-Wasik M, Peulen H, Giuliani M, Mantel F, Belderbos J, Grills I, Sonke JJ. Modeling radiation pneumonitis of pulmonary stereotactic body radiotherapy: The impact of a local dose-effect relationship for lung perfusion loss. Radiother Oncol 2019; 132:142-7 (NKI). 1315. Sharma, A, Özayral, S, Caserto, JS, ten Cate, R, Anders, NM, Barnett, JD, Kandala, SK, Henderson, E, Stewart, J, Liapi, E, Rudek, MA, Franken, NAP, Oei, AL, Korangath, P, Bunz, F & Ivkov, R . Increased uptake of doxorubicin by cells undergoing heat stress does not explain its synergistic cytotoxicity with hyperthermia. International journal of hyperthermia 2019;36:1:712-720 (Amsterdam UMC). 1316. Shu X, Wu L, Khankari NK, Shu XO, Wang TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah P, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W. Authors' response: associations of obesity and circulating insulin and glucose with breast cancer risk. Int J Epidemiol 2019; 48:1016-7 [Comment] (NKI). 1317. Sibinga Mulder, BG, Feshtali, S, Fariña Sarasqueta, A, Vahrmeijer, AL, Swijnenburg, R-J, Bonsing, BA & Mieog, JSD . A Prospective Clinical Trial to Determine the Effect of Intraoperative Ultrasound on Surgical Strategy and Resection Outcome in Patients with Pancreatic Cancer. Ultrasound in medicine & biology 2019;45:8:2019-2026 (Amsterdam UMC). 1318. Sievers, P, Appay, R, Schrimpf, D, Stichel, D, Reuss, DE, Wefers, AK, Reinhardt, A, Coras, R, Ruf, VC, Schmid, S, de Stricker, K, Boldt, HB, Kristensen, BW, Petersen, JK, Ulhøi, BP, Gardberg, M, Aronica, E, Hasselblatt, M, Brück, W, Bielle, F, Mokhtari, K, Lhermitte, B, Wick, W, Herold-Mende, C, Hänggi, D, Brandner, S, Giangaspero, F, Capper, D, Rushing, E, Wesseling, P, Pfister, SM, Figarella-Branger, D, von Deimling, A, Sahm, F & Jones, DTW . Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1. Acta Neuropathologica 2019;138:3:497-504 (Amsterdam UMC). 1319. Sigal M, Reines MDM, Mullerke S, Fischer C, Kapalczynska M, Berger H, Bakker ERM, Mollenkopf HJ, Rothenberg ME, Wiedenmann B, Sauer S, Meyer TF. R-spondin-3 induces secretory, antimicrobial Lgr5(+) cells in the stomach. Nat Cell Biol 2019; 21:812-23 (NKI). 1320. Silagy AW, Sanchez A, Manley BJ, Bensalah K, Bex A, Karam JA, Ljungberg B, Shuch B, Hakimi AA. Harnessing the Genomic Landscape of the Small Renal Mass to Guide Clinical Management. Eur Urol Focus 2019; 5:949-57 (NKI). 1321. Simon, C, Dietz, A & Leemans, CR . Quality assurance in head and neck cancer surgery: where are we, and where are we going?. Current Opinion in Otolaryngology and Head and Neck Surgery 2019;27:2:151-156 (Amsterdam UMC). 1322. Singh AA, Schuurman K, Nevedomskaya E, Stelloo S, Linder S, Droog M, Kim Y, Sanders J, van der Poel H, Bergman AM, Wessels LF, Zwart W. Optimized ChIP-seq method facilitates transcription factor profiling in human tumors. Life Sci Alliance 2019; 2:e201800115 (NKI). 1323. Skoetz, N, Goldkuhle, M, van Dalen, EC, Akl, EA, Trivella, M, Mustafa, RA, Nowak, A, Dahm, P, Schünemann, H, Bender, R & GRADE Working Group . GRADE guidelines 27: how to calculate absolute effects for time-to-event outcomes in summary of findings tables and Evidence Profiles. Journal of clinical epidemiology 2019 (Amsterdam UMC). 1324. Skoetz, N, Goldkuhle, M, Weigl, A, Dwan, K, Labonté, V, Dahm, P, Meerpohl, JJ, Djulbegovic, B & van Dalen, EC . Methodological review showed correct absolute effect size estimates for time-to-event outcomes in less than one-third of cancer-related systematic reviews. Journal of clinical epidemiology 2019;108::1-9. (Amsterdam UMC). 1325. Skovgaard Christiansen, I, Kuijvenhoven, JC, Bodtger, U, Naur, TMH, Ahmad, K, Singh Sidhu, J, Nessar, R, Salih, GN, Høegholm, A, Annema, JT & Clementsen, PF . Endoscopic Ultrasound with Bronchoscope-Guided Fine Needle Aspiration for the Diagnosis of Paraesophageally Located Lung Lesions. Respiration; international review of thoracic diseases 2019;97:4:277-283 (Amsterdam UMC). 1326. Slooter, MD, Eshuis, WJ, Cuesta, MA, Gisbertz, SS & van Berge Henegouwen, MI . Fluorescent imaging using indocyanine green during esophagectomy to prevent surgical morbidity: A systematic review and meta-analysis. Journal of thoracic disease 2019;11::S755-S765. (Amsterdam UMC). 1327. Slot, LM, Wormhoudt, TAM, Kwakkenbos, MJ, Wagner, K, Ballering, A, Jongejan, A, van Kampen, ACM, Guikema, JEJ, Bende, RJ & van Noesel, CJM . De novo gene mutations in normal human memory B cells. Leukemia 2019;33:5:1219-1230 (Amsterdam UMC). 1328. Slot, S, Raymakers, RAP, Schaap, N, Span, LFR, Koene, HR, Kersting, S, te Boekhorst, PAW, Westerman, M, Schouten, HC & Zweegman, S . Ruxolitinib in Myelofibrosis and Baseline Thrombocytopenia in Real Life: Results in Dutch Patients and Review of the Literature. Clinical Lymphoma Myeloma and Leukemia 2019;19:10:624-634 (Amsterdam UMC). 1329. Slotman, B & Gani, C . Online MR-guided radiotherapy – A new era in radiotherapy. Clinical and Translational Radiation Oncology 2019;18::102-103. (Amsterdam UMC). 1330. Sluiter, NR & Tuynman, JB . ASO Author Reflections: Advanced Imaging Allows Better Detection of Peritoneal Metastases. Annals of Surgical Oncology 2019;26:1:165-166 (Amsterdam UMC). 1331. Sluiter, NR, Vlek, SL, Wijsmuller, AR, Brandsma, HT, de Vet, HCW, van Grieken, NCT, Kazemier, G & Tuynman, JB . Narrow-Band Imaging Improves Detection of Colorectal Peritoneal Metastases: A Clinical Study Comparing Advanced Imaging Techniques. Annals of Surgical Oncology 2019;26:1:156- 164 (Amsterdam UMC). 1332. Smid M, Wilting S, Uhr K, Rodriguez-Gonzalez G, de Weerd V, Prager-Van der Smissen W, van der Vlugt-Daane M, van Galen A, Nik-Zainal S, Butler A, Martin S, Davies H, Staaf J, van de Vijver M, Richardson A, MacGrogan G, Salgado R, van den Eynden G, Purdie C, Thompson A, Caldas C, Span P, Sweep F, Simpson P, Lakhani S, Van Laere S, Desmedt C, Paradiso A, Eyfjord J, Broeks A, Vincent- Solomon A, Futreal A, Knappskog S, King T, Viari A, Borresen-Dale AL, Stunnenberg H, Stratton M, Foekens J, Sieuwerts A, Martens J. The circular RNome of primary breast cancer. Genome Res 2019; 29:356-66 (Amsterdam UMC & NKI). 1333. Smit EF, de Langen AJ. Pembrolizumab for all PD-L1-positive NSCLC. Lancet 2019; 393:1776-8 [Comment] (NKI). 1334. Smith TG, Dunn ME, Levin KY, Tsakraklides SP, Mitchell SA, van de Poll-Franse LV, Ward KC, Wiggins CL, Wu XC, Hurlbert M, Aaronson NK. Cancer survivor perspectives on sharing patient-generated health data with central cancer registries. Qual Life Res 2019; 28:2957-67 (NKI). 1335. Smith, NA, Baresel, PC, Jackson, CL, Ogolla, S, Toko, EN, Heit, S, Piriou, E, Sumba, OP, Middeldorp, JM, Colborn, KL & Rochford, R . Differences in the Epstein-Barr Virus gp350 IgA Antibody Response Are Associated With Increased Risk for Coinfection With a Second Strain of Epstein-Barr Virus. Journal of Infectious Diseases 2019;219:6:955-963 (Amsterdam UMC). 1336. Smitheman KN, Severson TM, Rajapurkar SR, McCabe MT, Karpinich N, Foley J, Pappalardi MB, Hughes A, Halsey W, Thomas E, Traini C, Federowicz KE, Laraio J, Mobegi F, Ferron-Brady G, Prinjha RK, Carpenter CL, Kruger RG, Wessels L, Mohammad HP. Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all-trans retinoic acid in acute myeloid leukemia across subtypes. Haematologica 2019; 104:1156-67 (NKI). 1337. Snoek, BC, Splunter, APV, Bleeker, MCG, Ruiten, MCV, Heideman, DAM, Rurup, WF, Verlaat, W, Schotman, H, Gent, MV, Trommel, NEV & Steenbergen, RDM . Cervical cancer detection by DNA methylation analysis in urine. Scientific Reports 2019;9:1:3088 (Amsterdam UMC & NKI). 1338. Snoek, BC, Verlaat, W, Babion, I, Novianti, PW, van de Wiel, MA, Wilting, SM, van Trommel, NE, Bleeker, MCG, Massuger, LFAG, Melchers, WJG, Sie, D, Heideman, DAM, Snijders, PJF, Meijer, CJLM & Steenbergen, RDM . Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer. International Journal of Cancer 2019;144:2:372- 379 (Amsterdam UMC & NKI). 1339. Snyder C, Smith K, Holzner B, Rivera YM, Bantug E, Brundage M, PRO Data Presentation Delphi Panel., Collaborators (31), Aaronson N. Making a picture worth a thousand numbers: recommendations for graphically displaying patient-reported outcomes data. Qual Life Res 2019; 28:345-56 (NKI). 1340. Sobral-Leite M, Salomon I, Opdam M, Kruger DT, Beelen KJ, van der Noort V, van Vlierberghe RLP, Blok EJ, Giardiello D, Sanders J, Van de Vijver K, Horlings HM, Kuppen PJK, Linn SC, Schmidt MK, Kok M. Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor- infiltrating lymphocytes. Breast Cancer Res 2019; 21:90 (NKI). 1341. Song JY. Inactivation of JNK1/2 promotes lung squamous cell carcinoma in Lkb1 deficiency mice. Biomed J Sci Tech Res 2019; 20:15356-7 (NKI). 1342. Song Y, Westerhuis JA, Aben N, Michaut M, Wessels LFA, Smilde AK. Principal component analysis of binary genomics data. Brief Bioinform 2019; 20:317-29 (NKI). 1343. Sonke JJ, Aznar M, Rasch C. Adaptive Radiotherapy for Anatomical Changes. Semin Radiat Oncol 2019; 29:245-57 (Amsterdam UMC & NKI). 1344. Soto M, Raaijmakers JA, Medema RH. Consequences of Genomic Diversification Induced by Segregation Errors. Trends Genet 2019; 35:279-91 (NKI). 1345. Spaan M, van den Belt-Dusebout AW, van den Heuvel-Eibrink MM, Hauptmann M, Lambalk CB, Burger CW, van Leeuwen FE. Risk of cancer in children and young adults conceived by assisted reproductive technology. Hum Reprod 2019; 34:740-50 (Amsterdam UMC & NKI). 1346. Sparano F, Aaronson NK, Cottone F, Piciocchi A, La SE, Anota A, Deliu N, Kieffer JM, Efficace F. Clinician-reported symptomatic adverse events in cancer trials: are they concordant with patient- reported outcomes? J Comp Eff Res 2019; 8:279-88 . (NKI). 1347. Sparano, F, Aaronson, NK, Sprangers, MAG, Fayers, P, Pusic, A, Kieffer, JM, Cottone, F, Rees, J, Pezold, M, Anota, A, Charton, E, Vignetti, M, Wan, C, Blazeby, J & Efficace, F . Inclusion of older patients with cancer in randomised controlled trials with patient-reported outcomes: A systematic review. BMJ supportive & palliative care 2019;9:4:451-463 (Amsterdam UMC & NKI). 1348. Sparidans RW, Li W, Schinkel AH, Beijnen JH. Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1122-1123:78-82 (NKI). 1349. Sparreboom, CL, Komen, N, Rizopoulos, D, van Westreenen, HL, Doornebosch, PG, Dekker, JWT, Menon, AG, Tuynman, JB, Daams, F, Lips, D, van Grevenstein, WMU, Karsten, TM, Lange, JF, D. Transanal total mesorectal excision: how are we doing so far?. Colorectal Disease 2019;21:7:767-774 (Amsterdam UMC). 1350. Spek, CA & Duitman, J . Is idiopathic pulmonary fibrosis a cancer-like disease?. ERJ open research 2019;5:1: (Amsterdam UMC). 1351. Spek, CA, Tekin, C & Bijlsma, MF . Protease-activated receptor-1 impedes prostate and intestinal tumor progression in mice: comment. Journal of thrombosis and haemostasis 2019;17:1:235-238 (Amsterdam UMC). 1352. Spinelli, A, Carvello, M, Sacchi, M, Bonifacio, C, Bertuzzi, A, Tuynman, J, Montorsi, M & Foppa, C . Transanal minimally invasive surgery (TAMIS) for anterior rectal GIST. Techniques in Coloproctology 2019;23:5:501-502 (Amsterdam UMC). 1353. Springer, S, Masica, DL, Molin, MD, Douville, C, Thoburn, CJ, Afsari, B, Li, L, Cohen, JD, Thompson, E, Allen, PJ, Klimstra, DS, Schattner, MA, Max Schmidt, C, Yip-Schneider, M, Simpson, RE, Castillo, CF-D, Mino-Kenudson, M, Brugge, W, Brand, RE, Singhi, AD, Scarpa, A, Lawlor, R, Salvia, R, Zamboni, G, Hong, S-M, Hwang, DW, Jang, J-Y, Kwon, W, Swan, N, Geoghegan, J, Falconi, M, Crippa, S, Doglioni, C, Paulino, J, Schulick, RD, Edil, BH, Park, W, Yachida, S, Hijioka, S, van Hooft, J, He, J, Weiss, MJ, Burkhart, R, Makary, M, Canto, MI, Goggins, MG, Ptak, J, Dobbyn, L, Schaefer, J, Sillman, N, Popoli, M, Klein, AP, Tomasetti, C, Karchin, R, Papadopoulos, N, Kinzler, KW, Vogelstein, B, Wolfgang, CL, Hruban, RH & Lennon, AM . A multimodality test to guide the management of patients with a pancreatic cyst. Science translational medicine 2019;11:501: (Amsterdam UMC). 1354. Spronk PER, Becherer BE, Hommes J, Keuter XHA, Young-Afat DA, Hoornweg MJ, Wouters MWJM, Mureau MAM, Rakhorst HA. How to improve patient safety and quality of care in breast implant surgery? First outcomes from the Dutch Breast Implant Registry (2015-2017). J Plast Reconstr Aesthet Surg 2019; 72:1607-15 (NKI). 1355. Spronk PER, Volders JH, van den Tol P, Smorenburg CH, Vrancken Peeters MTFD. Breast conserving therapy after neoadjuvant chemotherapy; data from the Dutch Breast Cancer Audit. Eur J Surg Oncol 2019; 45:110-7 (Amsterdam UMC & NKI). 1356. Spronk, I, Meijers, MC, Heins, MJ, Francke, AL, Elwyn, G, van Lindert, A, van Dulmen, S & van Vliet, LM . Availability and effectiveness of decision aids for supporting shared decision making in patients with advanced colorectal and lung cancer: Results from a systematic review. European Journal of Cancer Care 2019;28:3: (Amsterdam UMC). 1357. Stahlie EHA, Blankenstein SA, van Houdt WJ, Wouters MWJM, van Akkooi ACJ. A systematic review and meta-analysis of locoregional treatments for in-transit melanoma. J Surg Oncol 2019; 120:1056- 7 [Letter] (NKI). 1358. Stam B, Kwint M, Guckenberger M, Mantel F, Hope A, Giuliani M, Werner-Wasik M, Grills I, Sonke J, Belderbos J. Subgroup Survival Analysis In Stage I-II NSCLC Patients With a Central Tumor Partly Treated With Risk-Adapted SBRT. Int J Radiat Oncol Biol Phys 2019; 103:132-41 (NKI). 1359. Stapelfeldt CM, Klaver KM, Rosbjerg RS, Dalton SO, Bultmann U, Labriola M, Duijts SFA. A systematic review of interventions to retain chronically ill occupationally active employees in work: can findings be transferred to cancer survivors? Acta Oncol 2019; 58:548-65 . (NKI). 1360. Steenbruggen TG, Bouwer NI, Smorenburg CH, Rier HN, Jager A, Beelen K, Ten Tije AJ, de Jong PC, Drooger JC, Holterhues C, Kitzen JJEM, Levin M, Sonke GS. Radiological complete remission in HER2- positive metastatic breast cancer patients: what to do with trastuzumab? Breast Cancer Res Treat 2019; 178:597-605 . (NKI). 1361. Steenbruggen TG, van Seijen M, Janssen LM, van Ramshorst MS, van Werkhoven E, Vrancken Peeters MTFD, Wesseling J, Lips EH, Sonke GS. Prognostic value of residual disease after neoadjuvant therapy in HER2+ breast cancer evaluated by Residual Cancer Burden, Neoadjuvant Response Index & Neo- Bioscore. Clin Cancer Res 2019; 25:4985-92 (NKI). 1362. Steen-Louws C, Boross P, Prado J, Meeldijk J, Langenhorst JB, Huitema ADR, den Hartog MT, Boon L, Lafeber FPJG, Hack CE, Eijkelkamp N, Popov-Celeketic J. Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation. Pharm Res 2019; 37:17 [10 pp] (NKI). 1363. Steins, A, Ebbing, EA, Creemers, A, van der Zalm, AP, Jibodh, RA, Waasdorp, C, Meijer, SL, van Delden, OM, Krishnadath, KK, Hulshof, MCCM, Bennink, RJ, Punt, CJA, Medema, JP, Bijlsma, MF & van Laarhoven, HWM . Chemoradiation induces epithelial-to-mesenchymal transition in esophageal adenocarcinoma. International journal of cancer. Journal international du cancer 2019;145:10:2792- 2803 (Amsterdam UMC). 1364. Stelloo S, Bergman AM, Zwart W. Androgen receptor enhancer usage and the chromatin regulatory landscape in human prostate cancers. Endocr Relat Cancer 2019; 26:R267-R285 (NKI). 1365. Stijns, RCH, de Graaf, EJR, Punt, CJA, Nagtegaal, ID, Nuyttens, JJME, van Meerten, E, Tanis, PJ, de Hingh, IHJT, van der Schelling, GP, Acherman, Y, Leijtens, JWA, Bremers, AJA, Beets, GL, Hoff, C, Verhoef, C, Marijnen, CAM & de Wilt, JHW . Long-term Oncological and Functional Outcomes of Chemoradiotherapy Followed by Organ-Sparing Transanal Endoscopic Microsurgery for Distal Rectal Cancer: The CARTS Study. JAMA surgery 2019;154:1:47-54 (Amsterdam UMC & NKI). 1366. Stoop, TF, Ateeb, Z, Ghorbani, P, Scholten, L, Arnelo, U, Besselink, MG & del Chiaro, M . Impact of Endocrine and Exocrine Insufficiency on Quality of Life After Total Pancreatectomy. Annals of surgical oncology 2019 (Amsterdam UMC). 1367. Straub, D, Oude Elferink, RPJ, Jansen, PLM, Bergman, JJGHM, Parikh, K & Krishnadath, KK . Glyco- conjugated bile acids drive the initial metaplastic gland formation from multilayered glands through crypt-fission in a murine model. PLoS ONE 2019;14:7: (Amsterdam UMC). 1368. Streefkerk N, Heins MJ, Teepen JC, Feijen EAM, Bresters D, van Dulmen-den Broeder E, van der Heiden-van der Loo M, van den Heuvel-Eibrink MM, van Leeuwen FE, Loonen JJ, Van der Pal HJH, Ronckers CM, Versluys AB, Tissing WJE, Korevaar JC, Kremer LCM. The involvement of primary care physicians in care for childhood cancer survivors. Pediatr Blood Cancer 2019; 66:e27774 (9 pp) (NKI). 1369. Stricker PD, van Leeuwen PJ. Editorial Comment. J Urol 2019; 201:1142 [Editorial comment] (NKI). 1370. Strijker, M, Chen, JW, Mungroop, TH, Jamieson, NB, van Eijck, CH, Steyerberg, EW, Wilmink, JW, Groot Koerkamp, B, van Laarhoven, HW & Besselink, MG . Systematic review of clinical prediction models for survival after surgery for resectable pancreatic cancer. British journal of surgery 2019;106:4:342-354 (Amsterdam UMC). 1371. Strijker, M, Soer, EC, de Pastena, M, Creemers, A, Balduzzi, A, Beagan, JJ, Busch, OR, van Delden, OM, Halfwerk, H, van Hooft, JE, van Lienden, KP, Marchegiani, G, Meijer, SL, van Noesel, CJ, Reinten, RJ, Roos, E, Schokker, S, Verheij, J, van de Vijver, MJ, Waasdorp, C, Wilmink, JW, Ylstra, B, Besselink, MG, Bijlsma, MF, Dijk, F & van Laarhoven, HW . Circulating tumor DNA quantity is related to tumor volume and both predict survival in metastatic pancreatic ductal adenocarcinoma. International journal of cancer. Journal international du cancer 2019 (Amsterdam UMC). 1372. Stuiver MM, Stout NL, Dennett AM, Speksnijder CM, Campbell KL. An international perspective on integrating physiotherapists in oncology care. J Physiother 2019; 65:186-8 [Editorial] (NKI). 1373. Suerink M, Ripperger T, Messiaen L, Menko FH, Bourdeaut F, Colas C, Jongmans M, Goldberg Y, Nielsen M, Muleris M, van Kouwen M, Slavc I, Kratz C, Vasen HF, Brugires L, Legius E, Wimmer K. Constitutional mismatch repair deficiency as a differential diagnosis of neurofibromatosis type 1: consensus guidelines for testing a child without malignancy. J Med Genet 2019; 56:53-62 (NKI). 1374. Suker, M, Koerkamp, BG, Coene, PP, van der Harst, E, Bonsing, BA, Vahrmeijer, AL, Mieog, JSD, Swijnenburg, RJ, Dwarkasing, RS, Roos, D & van Eijck, CHJ . Yield of staging laparoscopy before treatment of locally advanced pancreatic cancer to detect occult metastases. European journal of surgical oncology 2019;45:10:1906-1911 (Amsterdam UMC). 1375. Sun J, Nagel R, Zaal EA, Ugalde AP, Han R, Proost N, Song JY, Pataskar A, Burylo A, Fu H, Poelarends GJ, van de Ven M, van Tellingen O, Berkers CR, Agami R. SLC1A3 contributes to L-asparaginase resistance in solid tumors. EMBO J 2019; 38:e102147 (NKI). 1376. Sustic T, Bosdriesz E, van Wageningen S, Wessels LFA, Bernards R. RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer. Transl Oncol 2019; 13:201-11 (NKI). 1377. Swaan, A, Mannaerts, CK, Muller, BG, van Kollenburg, RAA, Lucas, M, Savci-Heijink, CD, van Leeuwen, TG, de Reijke, TM & de Bruin, DM . The First In Vivo Needle-Based Optical Coherence Tomography in Human Prostate: A Safety and Feasibility Study. Lasers in surgery and medicine 2019;51:5:390-398 (Amsterdam UMC). 1378. Swaan, A, Muller, BG, Wilk, LS, Almasian, M, van Kollenburg, RAA, Zwartkruis, E, Rozendaal, LR, de Bruin, DM, Faber, DJ, van Leeuwen, TG & van Herk, MB . One-to-one registration of en-face optical coherence tomography attenuation coefficients with histology of a prostatectomy specimen. Journal of biophotonics 2019;12:4:e201800274 (Amsterdam UMC). 1379. Sweegers M, Altenburg T, Brug J, May A, van Vulpen J, Aaronson N, Arbane G, Bohus M, Courneya K, Daley A, Galvao D, Garrod R, Griffith K, van Harten W, Hayes S, Herrero-Roman F, Kersten M, Lucia A, McConnachie A, van Mechelen W, Mutrie N, Newton R, Nollet F, Potthoff K, Schmidt M, Schmitz K, Schulz K, Sonke G, Steindorf K, Stuiver M, Taaffe D, Thorsen L, Twisk J, Velthuis M, Wenzel J, Winters- Stone K, Wiskemann J, Chin AP, Buffart L. Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: a meta-analysis of individual patient data. Br J Sports Med 2019; 53:812 (Amsterdam UMC & NKI). 1380. Sweegers MG, Boyle T, Vallance JK, Chinapaw MJ, Brug J, Aaronson NK, D'Silva A, Kampshoff CS, Lynch BM, Nollet F, Phillips SM, Stuiver MM, van Waart H, Wang X, Buffart LM, Altenburg TM. Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors. Int J Behav Nutr Phys Act 2019; 16:66 (NKI). 1381. Sweegers, MG, Boyle, T, Vallance, JK, Chinapaw, MJ, Brug, J, Aaronson, NK, D. Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors. International Journal of Behavioral Nutrition and Physical Activity 2019;16:1: (Amsterdam UMC). 1382. Sweegers, MG, Buffart, LM, van Veldhuizen, WM, Geleijn, E, Verheul, HMW, Brug, J, Chinapaw, MJM & Altenburg, TM . How Does a Supervised Exercise Program Improve Quality of Life in Patients with Cancer?. The Oncologist 2019;24:6:e374-e383 (Amsterdam UMC). 1383. Szijgyarto Z, Flach KD, Opdam M, Palmieri C, Linn SC, Wesseling J, Ali S, Bliss JM, Cheang MCU, Zwart W, Coombes RC. Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)-PathIES. Breast Cancer Res Treat 2019; 175:149-63 (NKI). 1384. Takeuchi, M, Ajani, JA, Fang, X, Pfeiffer, P, Takeuchi, M & van Laarhoven, HWM . Meta-enrichment analyses to identify advanced gastric cancer patients who achieve a higher response to s-1/cisplatin. Cancers 2019;11:6: (Amsterdam UMC). 1385. Tamminga, SJ, Braspenning, AM, Haste, A, Sharp, L, Frings-Dresen, MHW & de Boer, AGEM . Barriers to and Facilitators of Implementing Programs for Return to Work (RTW) of Cancer Survivors in Four European Countries: A Qualitative Study. Journal of occupational rehabilitation 2019;29:3:550-559 (Amsterdam UMC). 1386. Tamminga, SJ, Coenen, P, Paalman, C, de Boer, AGEM, Aaronson, NK, Oldenburg, HSA, van Leeuwen, FE, van der Beek, AJ, Duijts, SFA & Schaapveld, M . Factors associated with an adverse work outcome in breast cancer survivors 5–10 years after diagnosis: a cross-sectional study. Journal of Cancer Survivorship 2019;13:1:108-116 (Amsterdam UMC & NKI). 1387. Tamminga, SJ, Verbeek, JHAM, Bos, MMEM, Fons, G, Kitzen, JJEM, Plaisier, PW, Frings-Dresen, MHW & de Boer, AGEM . Two-Year Follow-Up of a Multi-centre Randomized Controlled Trial to Study Effectiveness of a Hospital-Based Work Support Intervention for Cancer Patients. Journal of occupational rehabilitation 2019 (Amsterdam UMC). 1388. Tamminga, SJ, Wolvers, MDJ, Greidanus, MA, Zaman, AGNM, Braspenning, AM, Frings-Dresen, MHW & de Boer, AGEM . Employees Diagnosed with Cancer: Current Perspectives and Future Directions from an Employer’s Point of View. Journal of occupational rehabilitation 2019;29:2:472-474 (Amsterdam UMC). 1389. Tang, M, O. PARAGON: A Phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors. Gynecologic oncology 2019 (Amsterdam UMC). 1390. Tanis, PJ . Refining the role of adjuvant chemotherapy in stage III colon cancer. Colorectal disease 2019;21:2:135-136 (Amsterdam UMC). 1391. Tas, ML, Nagtegaal, M, Kraal, KCJM, Tytgat, GAM, Abeling, NGGM, Pluijm, SMF, Zwaan, CM, de Keizer, B, Molenaar, JJ & van Noesel, MM . Neuroblastoma stage 4S: Tumor regression rate and risk factors of progressive disease. Pediatric blood & cancer 2019 (Amsterdam UMC). 1392. Tax, C, Govaert, PHM, Stommel, MWJ, Besselink, MGH, Gooszen, HG & Rovers, MM . The Value of Decision Analytical Modeling in Surgical Research: An Example of Laparoscopic Versus Open Distal Pancreatectomy. Annals of surgery 2019;269:3:530-536 (Amsterdam UMC). 1393. Te Molder L, Juksar J, Harkes R, Wang W, Kreft M, Sonnenberg A. Tetraspanin CD151 and integrin alpha3beta1 contribute to the stabilization of integrin alpha6beta4-containing cell-matrix adhesions. J Cell Sci 2019; 132(:jcs235366 (NKI). 1394. Teepen JC, Kremer LC, van der Heiden-van der Loo M, Tissing WJ, van der Pal HJ, van den Heuvel- Eibrink MM, Loonen JJ, Louwerens M, Versluys B, van Dulmen-den Broeder E, Visser O, Maduro JH, van Leeuwen FE, Ronckers CM. Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort. Cancer Causes Control 2019; 30:909-22 (Amsterdam UMC & NKI). 1395. Teepen, JC, Kok, JL, Kremer, LC, Tissing, WJE, van den Heuvel-Eibrink, MM, Loonen, JJ, Bresters, D, van der Pal, HJ, Versluys, B, van Dulmen-den Broeder, E, Nijsten, T, Hauptmann, M, Hollema, N, Dolsma, WV, van Leeuwen, FE & Ronckers, CCM . Long-Term Risk of Skin Cancer among Childhood Cancer Survivors: A DCOG-LATER Cohort Study. Journal of the National Cancer Institute 2019;111:8:845-853 (Amsterdam UMC). 1396. Teepen, JC, Ronckers, CCM & Kremer, LCM . Colorectal Cancer Screening in Childhood Cancer Survivors. Journal of the National Cancer Institute 2019;111:11:1114-1115 (Amsterdam UMC). 1397. ten Berg, S, Loeffen, EAH, van de Wetering, MD, Martens, DHJ, van Ede, CM, Kremer, LCM & Tissing, WJE . Development of pediatric oncology supportive care indicators: Evaluation of febrile neutropenia care in the north of the Netherlands. Pediatric blood & cancer 2019;66:2: (Amsterdam UMC). 1398. Ten Berge DMHJ, Hurkmans DP, den Besten I, Kloover JS, Mathijssen RHJ, Debets RJEM, Smit EF, Aerts JGJV. Tumour growth rate as a tool for response evaluation during PD-1 treatment for non- small cell lung cancer: a retrospective analysis. ERJ Open Res 2019; 5:00179-2019 (NKI). 1399. ten Broeke, SW, Rodríguez-Girondo, M, Suerink, M, Aretz, S, Bernstein, I, Capella, G, Engel, C, Gomez-Garcia, EB, van Hest, LP, von Knebel Doeberitz, M, Lagerstedt-Robinson, K, Letteboer, TGW, Moller, P, van Os, TA, Pineda, M, Rahner, N, Olderode-Berends, MJW, von Salome, J, Schackert, HK, Spruijt, L, Steinke-Lange, V, Wagner, A, Tops, CMJ & Nielsen, M . The apparent genetic anticipation in PMS2-associated lynch syndrome families is explained by birth-cohort effect. Cancer Epidemiology Biomarkers and Prevention 2019;28:6:1010-1014 (Amsterdam UMC). 1400. ten Tusscher, MR, Groen, WG, Geleijn, E, Sonke, GS, Konings, IR, van der Vorst, MJ, van Zweeden, A, Aaronson, NK & Stuiver, MM . Physical problems, functional limitations, and preferences for physical therapist-guided exercise programs among Dutch patients with metastatic breast cancer: a mixed methods study. Supportive Care in Cancer 2019;27:8:3061-3070 (Amsterdam UMC & NKI). 1401. Ter Heine R, Kane SP, Huitema ADR, Krasowski MD, van Maarseveen EM. Non-linear protein binding of phenytoin in clinical practice - development and validation of a mechanistic prediction model. Br J Clin Pharmacol 2019; 85:2360-8 (NKI). 1402. Ter Stege JA, Woerdeman LAE, Hahn DEE, van Huizum MA, van Duijnhoven FH, Kieffer JM, Retel VP, Sherman KA, Witkamp AJ, Oldenburg HSA, Bleiker EMA. The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial. BMC Med Inform Decis Mak 2019; 19:165 (NKI). 1403. ter Veer, E, van Oijen, MGH & van Laarhoven, HWM . The use of (Network) meta-analysis in clinical oncology. Frontiers in oncology 2019;9:AUG: (Amsterdam UMC). 1404. ter Voert, EEGW, Heijmen, L, van Asten, JJA, Wright, AJ, Nagtegaal, ID, Punt, CJA, de Wilt, JHW, van Laarhoven, HWM & Heerschap, A . Levels of choline-containing compounds in normal liver and liver metastases of colorectal cancer as recorded by 1H MRS. NMR in biomedicine 2019;32:1: (Amsterdam UMC). 1405. Testori AAE, Blankenstein SA, van Akkooi ACJ. Primary Melanoma: from History to Actual Debates. Curr Oncol Rep 2019; 21:112 (NKI). 1406. Testori AAE, Blankenstein SA, van Akkooi ACJ. Surgery for Metastatic Melanoma: an Evolving Concept. Curr Oncol Rep 2019; 21:98 (NKI). 1407. Tetar, SU, Bruynzeel, AME, Lagerwaard, FJ, Slotman, BJ, Bohoudi, O & Palacios, MA . Clinical implementation of magnetic resonance imaging guided adaptive radiotherapy for localized prostate cancer. Physics and Imaging in Radiation Oncology 2019;9::69-76 (Amsterdam UMC). 1408. the Childhood Liver Tumour Strategy Group (SIOPEL), Aronson, DC, Weeda, VOB, Maibach, R, Czauderna, P, Dall. Microscopically positive resection margin after hepatoblastoma resection: what is the impact on prognosis? A Childhood Liver Tumours Strategy Group (SIOPEL) report. European journal of cancer (Oxford, England 2019;106::126-132 (Amsterdam UMC). 1409. the Dutch HOVON group, Lugtenburg, PJ, Zijlstra, JM, Doorduijn, JK, Böhmer, LH, Hoogendoorn, M, Berenschot, HW, Beeker, A, van der Burg-de Graauw, NC, Schouten, HC, Bilgin, YM, Kersten, M-J, Koene, HR, Herbers, AHE, de Jong, D, Hijmering, N, Lam, KH, Chiţu, D, Brouwer, RE & van Imhoff, GW . Rituximab-PECC induction followed by 90Y-ibritumomab tiuxetan consolidation in relapsed or refractory DLBCL patients who are ineligible for or have failed ASCT: results from a phase II HOVON study. British journal of haematology 2019;187:3:347-355 (Amsterdam UMC). 1410. the Research Committee and the Guidelines Committee of the European Society of Coloproctology (ESCP), Bastiaenen, VP, Hovdenak Jakobsen, I, Labianca, R, Martling, A, Morton, DG, Primrose, JN, Tanis, PJ & Laurberg, S . Consensus and controversies regarding follow-up after treatment with curative intent of nonmetastatic colorectal cancer: a synopsis of guidelines used in countries represented in the European Society of Coloproctology. Colorectal disease 2019;21:4:392-416 (Amsterdam UMC). 1411. the STOPCAP M1 Radiotherapy Collaborators, Burdett, S, Boevé, LM, Ingleby, FC, Fisher, DJ, Rydzewska, LH, Vale, CL, van Andel, G, Clarke, NW, Hulshof, MC, James, ND, Parker, CC, Parmar, MK, Sweeney, CJ, Sydes, MR, Tombal, B, Verhagen, PC & Tierney, JF . Prostate Radiotherapy for Metastatic Hormone-sensitive Prostate Cancer: A STOPCAP Systematic Review and Meta-analysis. European urology 2019;76:1:115-124 (Amsterdam UMC). 1412. The ENETS 2016 Munich Advisory Board Participants, Ramage, JK, Valle, JW, Nieveen van Dijkum, EJM, Sundin, A, Pascher, A, Couvelard, A & Kloeppel, G . Colorectal Neuroendocrine Neoplasms. Neuroendocrinology 2019;108:1:45-53 (Amsterdam UMC). 1413. The ENETS 2016 Munich Advisory Board Participants, Toumpanakis, C, Fazio, N, Tiensuu Janson, E, Hörsch, D, Pascher, A, Reed, N, O Apos Toole, D, Nieveen van Dijkum, E, Partelli, S, Rinke, A, Kos- Kudla, B, Costa, F, Pape, U-F, Grozinsky-Glasberg, S & Scoazec, J-Y . Unmet Needs in Appendiceal Neuroendocrine Neoplasms. Neuroendocrinology 2019;108:1:37-44 (Amsterdam UMC). 1414. Theelen WSME, Baas P. Pembrolizumab monotherapy for PD-L1 >/=50% non-small cell lung cancer, undisputed first choice? Ann Transl Med 2019; 7:S140 [Editorial] . (NKI). 1415. Theelen, WSME, Kuilman, T, Schulze, K, Zou, W, Krijgsman, O, Peters, DDGC, Cornelissen, S, Monkhorst, K, Sarma, P, Sumiyoshi, T, Amler, LC, Willems, SM, Blaauwgeers, JLG, van Noesel, CJM, Peeper, DS, van den Heuvel, MM & Kowanetz, M . Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in nonsmall cell lung cancer. PLoS ONE 2019;14:5: (Amsterdam UMC & NKI). 1416. Theelen, WSME, Peulen, HMU, Lalezari, F, van der Noort, V, de Vries, JF, Aerts, JGJV, Dumoulin, DW, Bahce, I, Niemeijer, A-LN, de Langen, AJ, Monkhorst, K & Baas, P . Effect of Pembrolizumab after Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients with Advanced Non-Small Cell Lung Cancer: Results of the PEMBRO-RT Phase 2 Randomized Clinical Trial. JAMA Oncology 2019;5:9:1276-1282 (Amsterdam UMC & NKI). 1417. Thom B, Boekhout AH, Corcoran S, Adsuar R, Oeffinger KC, McCabe MS. Advanced Practice Providers and Survivorship Care: They Can Deliver. J Oncol Pract 2019; 15:e230-e237 (NKI). 1418. Thomeer, MG, Vandecaveye, V, Braun, L, Mayer, F, Franckena-Schouten, M, de Boer, P, Stoker, J, van Limbergen, E, Buist, M, Vergote, I, Hunink, M & van Doorn, H . Evaluation of T2-W MR imaging and diffusion-weighted imaging for the early post-treatment local response assessment of patients treated conservatively for cervical cancer: a multicentre study. European radiology 2019;29:1:309- 318 (Amsterdam UMC). 1419. Thommen DS. The First Shall (Be) Last: Understanding Durable T Cell Responses in Immunotherapy. Immunity 2019; 50:6-8 (NKI). 1420. Thong, MSY & Sprangers, MAG . New challenges in psycho-oncology: Studying the direct relationships between biological markers and patients' subjective experiences. Response to Cole. Psycho-oncology 2019;28:1:204-205 (Amsterdam UMC). 1421. Thorneloe, KS, Sepp, A, Zhang, S, Galinanes-Garcia, L, Galette, P, Al-Azzam, W, Vugts, DJ, van Dongen, G, Elsinga, P, Wiegers, J, Glaudemans, AWJM, Vincent, V, Renaux, J, Szapacs, M, Birchler, M, Cleveland, M, Bergstrom, M & Davies, M . The biodistribution and clearance of AlbudAb, a novel biopharmaceutical medicine platform, assessed via PET imaging in humans. EJNMMI Research 2019;9:45.: (Amsterdam UMC). 1422. Thunnissen, E . How to validate predictive immunohistochemistry testing in pathology?. Archives of pathology & laboratory medicine 2019;143:1:44176 (Amsterdam UMC). 1423. Thunnissen, E, Lissenberg-Witte, BI, van den Heuvel, MM, Monkhorst, K, Skov, BG, Sørensen, JB, Mellemgaard, A, Dingemans, AMC, Speel, EJM, de Langen, AJ, Hashemi, SMS, Bahce, I, van der Drift, MA, Looijen-Salamon, MG, Gosney, J, Postmus, PE, Samii, SMS, Duplaquet, F, Weynand, B, Durando, X, Penault-Llorca, F, Finn, S, Grady, AO, Oz, B, Akyurek, N, Buettner, R, Wolf, J, Bubendorf, L, Duin, S, Marondel, I, Heukamp, LC, Timens, W, Schuuring, EMD, Pauwels, P & Smit, EF . ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib. Lung Cancer 2019;138::13-18. (Amsterdam UMC & NKI). 1424. Tibben MM, Huijberts S, Li W, Schinkel AH, Gebretensae A, Rosing H, Beijnen JH. Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study. J Pharm Biomed Anal 2019; 173:169-75 (NKI). 1425. Tijssen RHN, Philippens MEP, Paulson ES, Glitzner M, Chugh B, Wetscherek A, Dubec M, Wang J, van der Heide UA. MRI commissioning of 1. 5T MR-linac systems - a multi-institutional study(NKI). 1426. Timmermans M, van der Hel O, Sonke GS, Van de Vijver KK, Van der Aa MA, Kruitwagen RF. The prognostic value of residual disease after neoadjuvant chemotherapy in advanced ovarian cancer; A systematic review. Gynecol Oncol 2019; 153:445-51 (NKI). 1427. Timmermans M, Zwakman N, Sonke GS, Van de Vijver KK, Duk MJ, Van der Aa MA, Kruitwagen RF. Perioperative change in CA125 is an independent prognostic factor for improved clinical outcome in advanced ovarian cancer. Eur J Obstet Gynecol Reprod Biol 2019; 240:364-9 (NKI). 1428. Timmermans, M, Sonke, GS, Slangen, BFM, Baalbergen, A, Bekkers, RLM, Fons, G, Gerestein, CG, Kruse, AJ, Roes, EM, Zusterzeel, PLM, van de Vijver, KK, Kruitwagen, RFPM & van der Aa, MA . Outcome of surgery in advanced ovarian cancer varies between geographical regions; opportunities for improvement in The Netherlands. European journal of surgical oncology 2019 (Amsterdam UMC & NKI). 1429. Tio, D, Kasiem, FR, Willemsen, M, van Doorn, R, van der Werf, N, Hoekzema, R, Luiten, RM & Bekkenk, MW . Expression of cancer/testis antigens in cutaneous melanoma: a systematic review. Melanoma research 2019;29:4:349-357 (Amsterdam UMC). 1430. Tio, DCKS, van Montfrans, C, Ruijter, CGH, Hoekzema, R & Bekkenk, MW . Effectiveness of 5% Topical Imiquimod for Lentigo Maligna Treatment. Acta dermato-venereologica 2019;99:10:884-888 (Amsterdam UMC). 1431. Tjon a Joe S, Pannekoek S, Kampman E, Hoedjes M. Adherence to Diet and Body Weight Recommendations among Cancer Survivors after Completion of Initial Cancer Treatment: A Systematic Review of the Literature. Nutr Cancer 2019; 71:367-74 (NKI). 1432. Toes-Zoutendijk, E, Bonfrer, JMG, Ramakers, C, Thelen, M, Spaander, MCW, Dekker, E, van der Meulen, MP, Buskermolen, M, van Vuuren, AJ, Kuipers, EJ, van Kemenade, FJ, van Velthuysen, M-LF, Thomeer, MGJ, van Veldhuizen, H, van Ballegooijen, M, de Koning, HJ, van Leerdam, ME & Lansdorp- Vogelaar, I . Quality monitoring of a fit-based colorectal cancer screening program. Clinical chemistry 2019;65:3:419-426 (Amsterdam UMC & NKI). 1433. Tol, JP, Dahele, M, Gregoire, V, Overgaard, J, Slotman, BJ & Verbakel, WFAR . Analysis of EORTC- 1219-DAHANCA-29 trial plans demonstrates the potential of knowledge-based planning to provide patient-specific treatment plan quality assurance. Radiotherapy and Oncology 2019;130::75-81. (Amsterdam UMC). 1434. Torp, S, Paraponaris, A, van Hoof, E, Lindbohm, M-L, Tamminga, SJ, Alleaume, C, van Campenhout, N, Sharp, L & de Boer, AGEM . Work-Related Outcomes in Self-Employed Cancer Survivors: A European Multi-country Study. Journal of occupational rehabilitation 2019;29:2:361-374 (Amsterdam UMC). 1435. Torres-Xirau I, Olaciregui-Ruiz I, van der Heide UA, Mans A. 2D EPID dosimetry for an MR-linac: proof of concept. Med Phys 2019; 46:4193-203 (NKI). 1436. Tran MGB, Barod R, Bex A. Re: Philip S. Macklin, Mark E(NKI). 1437. Trebeschi S, Drago SG, Birkbak NJ, Kurilova I, Calin AM, Pizzi AD, Lalezari F, Lambregts DMJ, Rohaan M, Parmar C, Hartemink KJ, Swanton C, Haanen JBAG, Blank CU, Smit EF, Beets-Tan RGH, Aerts HJWL. Predicting Response to Cancer Immunotherapy using Non-invasive Radiomic Biomarkers. Ann Oncol 2019; 30:998-1004 (NKI). 1438. Treffers, LW, van Houdt, M, Bruggeman, CW, Heineke, MH, Zhao, XW, van der Heijden, J, Nagelkerke, SQ, Verkuijlen, PJJH, Geissler, J, Lissenberg-Thunnissen, S, Valerius, T, Peipp, M, Franke, K, van Bruggen, R, Kuijpers, TW, van Egmond, M, Vidarsson, G, Matlung, HL & van den Berg, TK . FcγRIIIb restricts antibody-dependent destruction of cancer cells by human neutrophils. Frontiers in Immunology 2019;10:JAN: (Amsterdam UMC). 1439. Trip AK, Jensen MB, Kallehauge JF, Lukacova S. Individualizing the radiotherapy target volume for glioblastoma using DTI-MRI: a phase 0 study on coverage of recurrences. Acta Oncol 2019; 58:1532-5 (NKI). 1440. Tsai, AYC, Mavroveli, S, Miskovic, D, van Oostendorp, S, Adamina, M, Hompes, R, Aigner, F, Spinelli, A, Warusavitarne, J, Knol, J, Albert, M, Nassif, G, Bemelman, W, Boni, L, Ovesen, H, Austin, R, Muratore, A, Seitinger, G, Sietses, C, Lacy, AM, Tuynman, JB, Bonjer, HJ & Hanna, GB . Surgical Quality Assurance in COLOR III: Standardization and Competency Assessment in a Randomized Controlled Trial. Annals of surgery 2019;270:5:768-774 (Amsterdam UMC). 1441. Tsoli, M, Shen, H, Mayoh, C, Franshaw, L, Ehteda, A, Upton, D, Carvalho, D, Vinci, M, Meel, MH, van Vuurden, D, Plessier, A, Castel, D, Drissi, R, Farrell, M, Cryan, J, Crimmins, D, Caird, J, Pears, J, Francis, S, Ludlow, LEA, Carai, A, Mastronuzzi, A, Liu, B, Hansford, J, Gottardo, N, Hassall, T, Kirby, M, Fouladi, M, Hawkins, C, Monje, M, Grill, J, Jones, C, Hulleman, E & Ziegler, DS . International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma. Journal of Neuro-Oncology 2019;141:2:253-263 (Amsterdam UMC). 1442. Tuit S, Salvagno C, Kapellos TS, Hau CS, Seep L, Oestreich M, Klee K, de Visser KE, Ulas T, Schultze JL. Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients. Cell Rep 2019; 29:1221-35 (NKI). 1443. Tummers, WS, Groen, JV, Sibinga Mulder, BG, Farina-Sarasqueta, A, Morreau, J, Putter, H, van de Velde, CJ, Vahrmeijer, AL, Bonsing, BA, Mieog, JS & Swijnenburg, RJ . Impact of resection margin status on recurrence and survival in pancreatic cancer surgery. British journal of surgery 2019;106:8:1055-1065 (Amsterdam UMC). 1444. Tummers, WS, Miller, SE, Teraphongphom, NT, van den Berg, NS, Hasan, A, Longacre, TA, Fisher, GA, Bonsing, BA, Vahrmeijer, AL, Gambhir, SS, Swijnenburg, R-J, Rosenthal, EL & Poultsides, GA . Detection of visually occult metastatic lymph nodes using molecularly targeted fluorescent imaging during surgical resection of pancreatic cancer. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:7:883-890 (Amsterdam UMC). 1445. Turco, S, el Kaffas, A, Zhou, J, Lutz, AM, Wijkstra, H, Willmann, JK & Mischi, M . Pharmacokinetic Modeling of Targeted Ultrasound Contrast Agents for Quantitative Assessment of Anti-Angiogenic Therapy: a Longitudinal Case-Control Study in Colon Cancer. Molecular imaging and biology : MIB 2019;21:4:633–643 (Amsterdam UMC). 1446. Tuyaerts, S, Rombauts, K, Everaert, T, van Nuffel, AMT & Amant, F . A phase 2 study to assess the immunomodulatory capacity of a lecithin-based delivery system of curcumin in endometrial cancer. Frontiers in Nutrition 2019;5:138.: (Amsterdam UMC). 1447. Tuyaerts, S, Van Nuffel, AMT, Naert, E, Van Dam, PA, Vuylsteke, P, De Caluwé, A, Aspeslagh, S, Dirix, P, Lippens, L, De Jaeghere, E, Amant, F, Vandecasteele, K & Denys, H . PRIMMO study protocol. BMC cancer 2019;19:1: (Amsterdam UMC). 1448. Tyritzis SI, Kalampokis N, Grivas N, van der Poel HG, Wiklund NP. Robot-assisted extended lymphadenectomy in prostate cancer. Minerva Chir 2019; 74:88-96 (NKI). 1449. Uitentuis SE, Louwman MWJ, van Akkooi ACJ, Bekkenk M. Treatment and survival of Merkel cell carcinoma since 1993: a population-based cohort study in the Netherlands. J Am Acad Dermatol 2019; 81:977-83 (Amsterdam UMC & NKI). 1450. Ukkonen, H, Vuokila, S, Mikkonen, JJW, Dekker, H, Schulten, EAJM, Bloemena, E, Valdez, TA, Kullaa, AM & Singh, SP . Biochemical Changes in Irradiated Oral Mucosa. Biosensors 2019;9:1: (Amsterdam UMC). 1451. UMBRELLA study group, Gregorowitsch, ML, van den Bongard, HJGD, Couwenberg, AM, Young-Afat, DA, Haaring, C, van Dalen, T, Schoenmaeckers, EJP, Agterof, MJ, Baas, IO, Sier, MF, Ernst, MF, van Hummel, R & Verkooijen, HM . Self-reported work ability in breast cancer survivors; a prospective cohort study in the Netherlands. Breast (Edinburgh, Scotland) 2019;48::45-53 (Amsterdam UMC). 1452. UMBRELLA study group, Gregorowitsch, ML, Verkooijen, HM, Houweling, A, Fuhler, N, Koelemij, R, Schoenmaeckers, EJP, Sier, MF, Ernst, MF, Witkamp, AJ, van Dalen, T, Young-Afat, DA & van den Bongard, DHJG . Impact of modern-day axillary treatment on patient reported arm morbidity and physical functioning in breast cancer patients. Radiotherapy and oncology 2019;131::221-228 (Amsterdam UMC). 1453. Ursin G, Malila N, Chang-Claude J, Gunter M, Kaaks R, Kampman E, Lambe M, van Leeuwen F, Magnusson P, Nilbert MC, Romundstad PR, Roosli M, Ryel AL, Dos-Santos-Silva I, Stenbeck M, Storm HH, Swerdlow A, Vineis P, Knudsen GPS. Sharing data safely while preserving privacy. Lancet 2019; 394:1902 [Letter] (NKI). 1454. Ursin G, Stenbeck M, Chang-Claude J, Gunter M, Kaaks R, Kampman E, Lambe M, van Leeuwen F, Magnusson P, Malila N, Nilbert MC, Romundstad PR, Roosli M, Ryel AL, Dos-Santos-Silva I, Storm HH, Swerdlow A, Vineis P, Knudsen GPS. Data must be shared-also with researchers outside of Europe. Lancet 2019; 394:1902-3 [Letter] (NKI). 1455. Usmani, SZ, Nahi, H, Mateos, M-V, van de Donk, NWCJ, Chari, A, Kaufman, JL, Moreau, P, Oriol, A, Plesner, T, Benboubker, L, Hellemans, P, Masterson, T, Clemens, PL, Luo, M, Liu, K & San-Miguel, J . Subcutaneous delivery of daratumumab in relapsed or refractory multiple myeloma. Blood 2019;134:8:668-677 (Amsterdam UMC). 1456. Uvyn, A, de Coen, R, Gruijs, M, Tuk, CW, de Vrieze, J, van Egmond, M & de Geest, BG . Efficient Innate Immune Killing of Cancer Cells Triggered by Cell-Surface Anchoring of Multivalent Antibody- Recruiting Polymers. Angewandte Chemie International Edition in English 2019;58:37:12988-12993 (Amsterdam UMC). 1457. Uz, ZH, Ince, C, Rassam, F, Ergin, BL, van Lienden, KP & van Gulik, TM . Assessment of hepatic microvascular flow and density in patients undergoing preoperative portal vein embolization. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:2:187-194 (Amsterdam UMC). 1458. Vaarwerk B, Hol MLF, Schoot RA, Breunis WB, de Win MML, Westerveld H, Fajardo RD, Saeed P, van den Brekel MW, Pieters BR, Strackee SD, Smeele LE, Merks JHM. AMORE treatment as salvage treatment in children and young adults with relapsed head-neck rhabdomyosarcoma. Radiother Oncol 2019; 131:21-6 (Amsterdam UMC & NKI). 1459. Vaarwerk B, Schoot RA, Maurice-Stam H, Slater O, Hartley B, Saeed P, Gajdosova E, van den Brekel MW, Balm AJM, Hol MLF, van Jaarsveld S, Kremer LCM, Ronckers CM, Mandeville HC, Pieters BR, Gaze MN, Davila Fajardo R, Strackee SD, Dunaway D, Smeele LE, Chisholm JC, Caron HN, Grootenhuis MA, Merks JHM. Psychosocial well-being of long-term survivors of pediatric head-neck rhabdomyosarcoma. Pediatr Blood Cancer 2019; 66(2):e27498:e27498 (9 pp) (Amsterdam UMC & NKI). 1460. Vaarwerk, B, Schoot, RA, Maurice-Stam, H, Slater, O, Hartley, B, Saeed, P, Gajdosova, E, van den Brekel, MW, Balm, AJM, Hol, MLF, van Jaarsveld, S, Kremer, LCM, Ronckers, CM, Mandeville, HC, Pieters, BR, Gaze, MN, Davila Fajardo, R, Strackee, SD, Dunaway, D, Smeele, LE, Chisholm, JC, Caron, HN, Grootenhuis, MA & Merks, JHM . Psychosocial well-being of long-term survivors of pediatric head–neck rhabdomyosarcoma. Pediatric blood & cancer 2019;66:2: (Amsterdam UMC). 1461. Valent, P, Orazi, A, Savona, MR, Patnaik, MM, Onida, F, van de Loosdrecht, AA, Haase, D, Haferlach, T, Elena, C, Pleyer, L, Kern, W, Pemovska, T, Vladimer, GI, Schanz, J, Keller, A, Lübbert, M, Lion, T, Sotlar, K, Reiter, A, de Witte, T, Pfeilstöcker, M, Geissler, K, Padron, E, Deininger, M, Orfao, A, Horny, H-P, Greenberg, PL, Arber, DA, Malcovati, L & Bennett, JM . Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions. Haematologica 2019;104:10:1935-1949 (Amsterdam UMC). 1462. Valkema, MJ, Noordman, BJ, Wijnhoven, BPL, Spaander, MCW, Biermann, K, Lagarde, SM, Bennink, RJ, Schreurs, WMJ, Roef, MJ, Hobbelink, MGG, Janssen, MJR, Graven, LH, van Lanschot, JJB & Valkema, R . Accuracy of 18F-FDG PET/CT in Predicting Residual Disease After Neoadjuvant Chemoradiotherapy for Esophageal Cancer. Journal of nuclear medicine 2019;60:11:1553-1559 (Amsterdam UMC). 1463. Valstar, MH, Owers, EC, Al-Mamgani, A, Smeele, LE, van de Kamer, JB, Sonke, J-J & Vogel, WV . Prostate-specific membrane antigen positron emission tomography/computed tomography as a potential tool to assess and guide salivary gland irradiation. Physics and Imaging in Radiation Oncology 2019;9::65-68. (Amsterdam UMC). 1464. van Akkooi ACJ, Hayes A. Recent developments in lymph node surgery for melanoma. Br J Dermatol 2019; 180:5-7 [Editorial] (NKI). 1465. van Andel, H, Kocemba, KA, Spaargaren, M & Pals, ST . Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options. Leukemia 2019;33:5:1063-1075 (Amsterdam UMC). 1466. van Arensbergen J, Pagie L, FitzPatrick VD, de Haas M, Baltissen MP, Comoglio F, van der Weide RH, Teunissen H, Vosa U, Franke L, de Wit E, Vermeulen M, Bussemaker HJ, van Steensel B. High- throughput identification of human SNPs affecting regulatory element activity. Nat Genet 2019; 51:1160-9 (NKI). 1467. van As, JW, van den Berg, H & van Dalen, EC . Medical interventions for the prevention of platinum- induced hearing loss in children with cancer. Cochrane database of systematic reviews (Online) 2019;5:5: (Amsterdam UMC). 1468. van Baal, JOAM, van de Vijver, KK, Algera, MD, van der Aa, MA, Sonke, GS, van Driel, WJ, Kenter, GG, Amant, FC & Lok, CAR . The effect of adjuvant chemotherapy on survival in patients with FIGO stage I high-grade serous ovarian cancer. Gynecologic Oncology 2019;153:3:562-567 (Amsterdam UMC & NKI). 1469. van Baar, GJC, Liberton, NPTJ, Forouzanfar, T, Winters, HAH & Leusink, FKJ . Accuracy of computer- assisted surgery in mandibular reconstruction: A postoperative evaluation guideline. Oral Oncology 2019;88::1-8. (Amsterdam UMC). 1470. van Bastelaar J, Granzier R, van Roozendaal LM, van Kuijk SMJ, Lerut AV, Beets G, Hadfoune M, Olde Damink S, Vissers YLJ. Analysis of TNF-alpha and interleukin-6 in seroma of patients undergoing mastectomy with or without flap fixation: is there a predictive value for seroma formation and its sequelae? Surg Oncol 2019; 28:36-41 . (NKI). 1471. van Beek S, Jonker M, Hamming-Vrieze O, Al-Mamgani A, Navran A, Remeijer P, van de Kamer JB. Protocolised way to cope with anatomical changes in head & neck cancer during the course of radiotherapy. Tech Innov Patient Support Radiat Oncol 2019; 12:34-40 (NKI). 1472. van Beek, FE, Wijnhoven, LMA, Jansen, F, Custers, JAE, Aukema, EJ, Coupé, VMH, Cuijpers, P, van der Lee, ML, Lissenberg-Witte, BI, Wijnen, B, Prins, JB & Verdonck-de Leeuw, IM . Prevalence of adjustment disorder among cancer patients, and the reach, effectiveness, cost-utility and budget impact of tailored psychological treatment: Study protocol of a randomized controlled trial. BMC Psychology 2019;7:1: (Amsterdam UMC). 1473. van Bemmel JG, Galupa R, Gard C, Servant N, Picard C, Davies J, Szempruch AJ, Zhan Y, Zylicz JJ, Nora EP, Lameiras S, de Wit E, Gentien D, Baulande S, Giorgetti L, Guttman M, Hughes JR, Higgs DR, Gribnau J, Heard E. The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist. Nat Genet 2019; 51:1024-34 (NKI). 1474. van Berlo, D, Khmelinskii, A, Gasparini, A, Salguero, FJ, Floot, B, de Wit, N, van de Ven, M, Song, JY, Coppes, RP, Verheij, M, Sonke, JJ & Vens, C . Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models. Radiotherapy and Oncology 2019;138::17-24 (Amsterdam UMC & NKI). 1475. van Beusekom B, Wezel N, Hekkelman ML, Perrakis A, Emsley P, Joosten RP. Building and rebuilding N-glycans in protein structure models. Acta Crystallogr D Struct Biol 2019; 75:416-25 (NKI). 1476. van Bilsen, WPH, Kovaleva, A, Bleeker, MCG, King, AJ, Bruisten, SM, Brokking, W, de Vries, HJC, Meijer, CJLM & Schim van der Loeff, MF . HPV infections and flat penile lesions of the penis in men who have sex with men. PAPILLOMAVIRUS RESEARCH 2019;8::100173 (Amsterdam UMC). 1477. van Bommel A, Spronk P, Mureau M, Siesling S, Smorenburg C, Tollenaar R, Vrancken Peeters MJ, van Dalen T. Breast-Contour-Preserving Procedure as a Multidisciplinary Parameter of Esthetic Outcome in Breast Cancer Treatment in The Netherlands. Ann Surg Oncol 2019; 26:1704-11 (NKI). 1478. van Bruggen, JAC, Martens, AWJ, Fraietta, JA, Hofland, T, Tonino, SH, Eldering, E, Levin, M-D, Siska, PJ, Endstra, S, Rathmell, JC, June, CH, Porter, DL, Melenhorst, JJ, Kater, AP & van der Windt, GJW . Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T- cell efficacy. Blood 2019;134:1:44-58 (Amsterdam UMC). 1479. van Bussel MTJ, Beijnen JH, Brandsma D. Intracranial antitumor responses of nivolumab and ipilimumab: a pharmacodynamic and pharmacokinetic perspective, a scoping systematic review. BMC Cancer 2019; 19:519 (NKI). 1480. Van Cutsem E, Huijberts S, Grothey A, Yaeger R, Cuyle PJ, Elez E, Fakih M, Montagut C, Peeters M, Yoshino T, Wasan H, Desai J, Ciardiello F, Gollerkeri A, Christy-Bittel J, Maharry K, Sandor V, Schellens JHM, Kopetz S, Tabernero J. Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer: Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study. J Clin Oncol 2019; 37:1460-9 (NKI). 1481. van de Donk, NWCJ . Reprint of “Immunomodulatory effects of CD38-targeting antibodies”. Immunology Letters 2019;205::71-77. (Amsterdam UMC). 1482. van de Donk, NWCJ, Casneuf, T, Di Cara, A, Parren, PW, Zweegman, S, van Kessel, B, Lokhorst, HM, Usmani, SZ, Lonial, S, Richardson, PG, Chiu, C, Mutis, T, Nijhof, IS & Sasser, AK . Impact of Fc gamma receptor polymorphisms on efficacy and safety of daratumumab in relapsed/refractory multiple myeloma. British Journal of Haematology 2019;184:3:475-479 (Amsterdam UMC). 1483. van de Haar J, Canisius S, Yu MK, Voest EE, Wessels LFA, Ideker T. Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell 2019; 177:1375-83 (NKI). 1484. van de Haar J, Hoes L, Voest E. Advancing molecular tumour boards: highly needed to maximise the impact of precision medicine. ESMO Open 2019; 4:e000516 [Editorial] (NKI). 1485. van de Langenberg D, Vlaanderen JJ, Dolle ME, Rookus MA, van Kerkhof LW, Vermeulen RC. Diet, Physical Activity, and Daylight Exposure Patterns in Night-Shift Workers and Day Workers. Ann Work Expo Health 2019; 63(1):9-21:9-21 (NKI). 1486. van de Lindt TN, Fast MF, van Kranen SR, Nowee ME, Jansen EPM, van der Heide UA, Sonke JJ. MRI- guided mid-position liver radiotherapy: Validation of image processing and registration steps. Radiother Oncol 2019; 138:132-40 (NKI). 1487. van de Loo, LEXM, van den Berg, MH, Overbeek, A, van Dijk, M, Damen, L, Lambalk, CB, Ronckers, CCM, van den Heuvel-Eibrink, MM, Kremer, LCM, van der Pal, HJ, Laven, JSE, Tissing, WJE, Loonen, JJ, Versluys, B, Bresters, D, Kaspers, GJL, van Leeuwen, FE, van Dulmen-den Broeder, E & DCOG LATER- VEVO Study Group . Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors. Fertility and Sterility 2019;111:2:372-380 (Amsterdam UMC & NKI). 1488. van de Ven M, Retel VP, Koffijberg H, van Harten WH, Ijzerman MJ. Variation in the time to treatment for stage III and IV non-small cell lung cancer patients for hospitals in the Netherlands. Lung Cancer 2019; 134:34-41 (NKI). 1489. van de Vijfeijken, SECM, Slot, M, Strackee, S, Becking, AG, de Lange, J, Smeele, LE & Schreuder, WH . Is Three-Dimensional Virtual Planning in Cranial Reconstruction for Advanced Cutaneous Squamous Cell Carcinoma of the Skull a Feasible Option?. Journal of craniofacial surgery 2019;30:8:2362-2367 (Amsterdam UMC & NKI). 1490. van de Vrie, R, Rutten, MJ, Asseler, JD, Leeflang, MM, Kenter, GG, Mol, BWJ & Buist, M . Laparoscopy for diagnosing resectability of disease in women with advanced ovarian cancer. Cochrane database of systematic reviews (Online) 2019;3:3: (Amsterdam UMC). 1491. van de Vrugt, HJ, Harmsen, T, Riepsaame, J, Alexantya, G, van Mil, SE, de Vries, Y, Bin Ali, R, Huijbers, IJ, Dorsman, JC, Wolthuis, RMF & te Riele, H . Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair. Scientific Reports 2019;9:1: (Amsterdam UMC & NKI). 1492. van den Berg MJ, van der Graaf Y, Deckers JW, de Kanter W, Algra A, Kappelle LJ, de Borst GJ, Cramer MM, Visseren FLJ. Smoking cessation and risk of recurrent cardiovascular events and mortality after a first manifestation of arterial disease. Am Heart J 2019; 213:112-22 (NKI). 1493. van den Berg, MMGA, Kok, DE, Posthuma, L, Kamps, L, Kelfkens, CS, Buist, N, Geenen, M, Haringhuizen, A, Heijns, JB, van Lieshout, RHMA, Los, M, Sommeijer, DW, Timmer-Bonte, JNH, de Kruif, ATCM, van Laarhoven, HWM, Kampman, E & Winkels, RM . Body composition is associated with risk of toxicity-induced modifications of treatment in women with stage I–IIIB breast cancer receiving chemotherapy. Breast cancer research and treatment 2019;173:2:475-481 (Amsterdam UMC). 1494. van den Berg, TK & Valerius, T . Myeloid immune-checkpoint inhibition enters the clinical stage. Nature reviews. Clinical oncology 2019;16::275-276. (Amsterdam UMC). 1495. van den Bergh R, Gandaglia G, Tilki D, Borgmann H, Ost P, Surcel C, Valerio M, Sooriakumaran P, Briganti A, Graefen M, van der Poel H, de la Taille A, Montorsi F, Ploussard G. Trends in Radical Prostatectomy Risk Group Distribution in a European Multicenter Analysis of 28 572 Patients: Towards Tailored Treatment. Eur Urol Focus 2019; 5:171-8 (NKI). 1496. van den Boorn, HG, Abu-Hanna, A, Ter Veer, E, van Kleef, JJ, Lordick, F, Stahl, M, Ajani, JA, Guimbaud, R, Park, SH, Dutton, SJ, Bang, Y-J, Boku, N, Mohammad, NH, Sprangers, MAG, Verhoeven, RHA, Zwinderman, AH, van Oijen, MGH & van Laarhoven, HWM . SOURCE. Cancers 2019;11:2:E187 (Amsterdam UMC). 1497. van den Borg, R, Leonetti, A, Tiseo, M, Giovannetti, E & Peters, GJ . Novel targeted strategies to overcome resistance in small-cell lung cancer: focus on PARP inhibitors and rovalpituzumab tesirine. Expert Review of Anticancer Therapy 2019;19:6:461-471 (Amsterdam UMC). 1498. van den Broeck T, van den Bergh RCN, Arfi N, Gross T, Moris L, Briers E, Cumberbatch M, De Santis M, Tilki D, Fanti S, Fossati N, Gillessen S, Grummet JP, Henry AM, Lardas M, Liew M, Rouviere O, Pecanka J, Mason MD, Schoots IG, van der Kwast TH, van der Poel HG, Wiegel T, Willemse PM, Yuan Y, Lam TB, Cornford P, Mottet N. Prognostic Value of Biochemical Recurrence Following Treatment with Curative Intent for Prostate Cancer: A Systematic Review. Eur Urol 2019; 75:967-87 (NKI). 1499. van den Broek AJ, Schmidt MK, van 't Veer LJ, Oldenburg HSA, Rutgers EJ, Russell NS, Smit VTHB, Voogd AC, Koppert LB, Siesling S, Jobsen JJ, Westenend PJ, van Leeuwen FE, Tollenaar RAEM. Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients. Ann Surg 2019; 270:364-72 (NKI). 1500. van den Dries K, Nahidiazar L, Slotman JA, Meddens MBM, Pandzic E, Joosten B, Ansems M, Schouwstra J, Meijer A, Steen R, Wijers M, Fransen J, Houtsmuller AB, Wiseman PW, Jalink K, Cambi A. Modular actin nano-architecture enables podosome protrusion and mechanosensing. Nat Commun 2019; 10:5171 (NKI). 1501. van den Ende RPJ, Kerkhof EM, Rigter LS, van Leerdam ME, Peters FP, van Triest B, Staring M, Marijnen CAM, van der Heide UA. Feasibility of gold fiducial markers as a surrogate for GTV position in image-guided radiotherapy of rectal cancer. Int J Radiat Oncol Biol Phys 2019; 105:1151-9 (NKI). 1502. van den Ende RPJ, Rigter LS, Kerkhof EM, van Persijn van Meerten EL, Rijkmans EC, Lambregts DMJ, van Triest B, van Leerdam ME, Staring M, Marijnen CAM, van der Heide UA. MRI visibility of gold fiducial markers for image-guided radiotherapy of rectal cancer. Radiother Oncol 2019; 132:93-9 (NKI). 1503. van den Ende, T, Abe Nijenhuis, FA, van den Boorn, HCG, ter Veer, E, Hulshof, MCCM, Gisbertz, SS, van Oijen, MGH & van Laarhoven, HWM . COMplot, A Graphical Presentation of Complication Profiles and Adverse Effects for the Curative Treatment of Gastric Cancer: A Systematic Review and Meta-Analysis. Frontiers in oncology 2019;9:684.: (Amsterdam UMC). 1504. van den Ende, T, Menting, SP, Ambarus, CA, van Oijen, MGH & van Laarhoven, HWM . Cutaneous Toxicity After Chemoradiotherapy and PD-L1 Inhibition in Two Patients with Esophageal Adenocarcinoma. oncologist 2019;24:4:e149-e153 (Amsterdam UMC). 1505. van den Ende, T, ter Veer, E, Machiels, ML, Mali, RMA, Abe Nijenhuis, FA, de Waal, L, Laarman, M, Gisbertz, SS, Hulshof, MCCM, van Oijen, MGH & van Laarhoven, HWM . The efficacy and safety of (Neo)adjuvant therapy for gastric cancer: A network meta-analysis. Cancers 2019;11:1: (Amsterdam UMC). 1506. van den Ende, T, Veer, E, Mali, RMA, van Berge Henegouwen, MI, Hulshof, MCCM, van Oijen, MGH & van Laarhoven, HWM . Prognostic and predictive factors for the curative treatment of esophageal and gastric cancer in randomized controlled trials: A systematic review and meta-analysis. Cancers 2019;11:4: (Amsterdam UMC). 1507. van den Tempel, N, Zelensky, AN, Odijk, H, Laffeber, C, Schmidt, CK, Brandsma, I, Demmers, J, Krawczyk, PM & Kanaar, R . On the mechanism of hyperthermia-induced BRCA2 protein degradation. Cancers 2019;11:1: (Amsterdam UMC). 1508. van den Wollenberg W, de Ruiter P, Nowee ME, Jansen EPM, Jan-Jakob S, Fast MF. Investigating the impact of patient arm position in an MR-linac on liver SBRT treatment plans. Med Phys 2019; 46:5144-51 (NKI). 1509. van der Aa, AAMA, Mannaerts, CK, Gayet, MCW, van der Linden, JC, Schrier, BP, Sedelaar, JPM, Mischi, M, Beerlage, HP & Wijkstra, H . Three-dimensional greyscale transrectal ultrasound-guidance and biopsy core preembedding for detection of prostate cancer: Dutch clinical cohort study. BMC urology 2019;19:1: (Amsterdam UMC). 1510. van der Bogt, RD, Noordman, BJ, Krishnadath, KK, Roumans, CAM, Schoon, EJ, Oostenbrug, LE, Siersema, PD, Vleggaar, FP, van Lanschot, JJB & Spaander, MCW . Endoscopic ultrasound measurements for detection of residual disease after neoadjuvant chemoradiotherapy for esophageal cancer. Endoscopy 2019;51:4:326-332 (Amsterdam UMC). 1511. van der Borden CL, Stoffers S, Lips EH, Wesseling J. Avoiding Overtreatment of Ductal Carcinoma in situ. Trends Cancer 2019; 5:391-3 (NKI). 1512. van der Heide UA, Frantzen-Steneker M, Astreinidou E, Nowee ME, van Houdt PJ. MRI basics for radiation oncologists. Clin Transl Radiat Oncol 2019; 18:74-9 (NKI). 1513. van der Heijden, M & Vermeulen, L . Stem cells in homeostasis and cancer of the gut. Molecular cancer 2019;18:1: (Amsterdam UMC). 1514. van der Heijden, M, de Jong, MC, Verhagen, CVM, de Roest, RH, Sanduleanu, S, Hoebers, F, Leemans, CR, Brakenhoff, RH, Vens, C, Verheij, M & van den Brekel, MWM . Acute hypoxia profile is a stronger prognostic factor than chronic hypoxia in advanced stage head and neck cancer patients. Cancers (Basel) 2019;11:4: (Amsterdam UMC & NKI). 1515. van der Heijden, M, Miedema, DM, Waclaw, B, Veenstra, VL, Lecca, MC, Nijman, LE, van Dijk, E, van Neerven, SM, Lodestijn, SC, Lenos, KJ, de Groot, NE, Prasetyanti, PR, Varea, AA, Winton, DJ, Medema, JP, Morrissey, E, Ylstra, B, Nowak, MA, Bijlsma, MF & Vermeulen, L . Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America 2019;116:13:6140-6145 (Amsterdam UMC). 1516. van der Hel OL, Timmermans M, van Altena AM, Kruitwagen RFPM, Slangen BFM, Sonke GS, Van de Vijver KK, Van der Aa MA. Overview of non-epithelial ovarian tumours: Incidence and survival in the Netherlands, 1989-2015. Eur J Cancer 2019; 118:97-104 (NKI). 1517. van der Hout, A, Neijenhuijs, KI, Jansen, F, van Uden-Kraan, CF, Aaronson, NK, Groenvold, M, Holzner, B, Terwee, CB, van de Poll-Franse, LV, Cuijpers, P & Verdonck-de Leeuw, IM . Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29. Supportive Care in Cancer 2019;27:7:2395-2412 (Amsterdam UMC & NKI). 1518. van der Kaaij RT, Voncken FEM, van Dieren JM, Snaebjornsson P, Korse CM, Grootscholten C, Aleman BMP, van Sandick JW. Elevated Pretreatment CEA and CA19-9 Levels are Related to Early Treatment Failure in Esophageal Adenocarcinoma. Am J Clin Oncol 2019; 42:345-50 (NKI). 1519. van der Leeden, M, Balland, C, Geleijn, E, Huijsmans, RJ, Dekker, J, Paul, MA, Dickhoff, C & Stuiver, MM . In-Hospital Mobilization, Physical Fitness, and Physical Functioning After Lung Cancer Surgery. The Annals of Thoracic Surgery 2019;107:6:1639-1646 (Amsterdam UMC). 1520. van der Linden, M, Oonk, MHM, van Doorn, HC, Bulten, J, van Dorst, EBL, Fons, G, Lok, CAR, van Poelgeest, MIE, Slangen, BMF, Massuger, LFAG & de Hullu, JA . Vulvar Paget disease: A national retrospective cohort study. Journal of the American Academy of Dermatology 2019;81:4:956-962 (Amsterdam UMC). 1521. van der Meer, MC, Bosman, PAN, Pieters, BR, Niatsetski, Y, van Wieringen, N, Alderliesten, T & Bel, A . Sensitivity of dose-volume indices to computation settings in high-dose-rate prostate brachytherapy treatment plan evaluation. Journal of applied clinical medical physics / American College of Medical Physics 2019;20:4:66-74 (Amsterdam UMC). 1522. Van der Meij, A, Damman, OC, Uiters, E & Timmermans, DRM . What benefits and harms are important for a decision about cervical screening? A study of the perspective of different subgroups of women.. Patient Preference and Adherence 2019;13::1005-1017. (Amsterdam UMC). 1523. van der Poel H, Grivas N, van Leeuwen P, Heijmink S, Schoots I. The role of MRI for detection and staging of radio- and focal therapy-recurrent prostate cancer. World J Urol 2019; 37:1485-90 (NKI). 1524. van der Poel H. Re: Addition of Radium-223 to Abiraterone Acetate and Prednisone or Prednisolone in Patients with Castration-resistant Prostate Cancer and Bone Metastases (ERA 223): A Randomised, Double-blind, Placebo-controlled, Phase 3 Trial. Eur Urol 2019; 76:705-6 [Letter] (NKI). 1525. van der Poel HG, van den Bergh RCN, Briers E, Cornford P, Govorov A, Henry AM, Lam TB, Mason MD, Rouviere O, De Santis M, Willemse PM, van Poppel H, Mottet N. Reply to Massimo Valerio, Mark Emberton, and Hashim U. Ahmed's Letter to the Editor re: Henk G(NKI). 1526. van der Poel, MJ, Barkhatov, L, Fuks, D, Berardi, G, Cipriani, F, Aljaiuossi, A, Lainas, P, Dagher, I, D. Multicentre propensity score-matched study of laparoscopic versus open repeat liver resection for colorectal liver metastases. British journal of surgery 2019;106:6:783-789 (Amsterdam UMC). 1527. van der Poel, MJ, Fichtinger, RS, Bemelmans, M, Bosscha, K, Braat, AE, de Boer, MT, Dejong, CHC, Doornebosch, PG, Draaisma, WA, Gerhards, MF, Gobardhan, PD, Gorgec, B, Hagendoorn, J, Kazemier, G, Klaase, J, Leclercq, WKG, Liem, MS, Lips, DJ, Marsman, HA, Mieog, JSD, Molenaar, QI, Nieuwenhuijs, VB, Nota, CL, Patijn, GA, Rijken, AM, Slooter, GD, Stommel, MWJ, Swijnenburg, R-J, Tanis, PJ, te Riele, WW, Terkivatan, TR, van den Tol, PM, van den Boezem, PB, van der Hoeven, JA, Vermaas, M, Hilal, MA, van Dam, RM, Besselink, MG, Zonderhuis, B, Rinkes, IB, Hoff, C & Oosterling, S . Implementation and outcome of minor and major minimally invasive liver surgery in the Netherlands. HPB 2019;21:12:1734-1743 (Amsterdam UMC). 1528. van der Poel, MJ, Tanis, PJ, Marsman, HA, Rijken, AM, Gertsen, EC, Ovaere, S, Gerhards, MF, Besselink, MG, D’Hondt, M & Gobardhan, PD . Laparoscopic combined resection of liver metastases and colorectal cancer: a multicenter, case-matched study using propensity scores. Surgical endoscopy 2019;33:4:1124-1130 (Amsterdam UMC). 1529. Van Der Pol, Y & Mouliere, F . Toward the Early Detection of Cancer by Decoding the Epigenetic and Environmental Fingerprints of Cell-Free DNA. Cancer Cell 2019;36:4:350-368 (Amsterdam UMC). 1530. van der Sande ME, Beets GL, Hupkens BJ, Breukink SO, Melenhorst J, Bakers FC, Lambregts DM, Grabsch HI, Beets-Tan RG, Maas M. Response assessment after (chemo)radiotherapy for rectal cancer: Why are we missing complete responses with MRI and endoscopy? Eur J Surg Oncol 2019; 45:1011-7 . (NKI). 1531. van der Sande ME, Hupkens BJP, Berbee M, van Kuijk SMJ, Maas M, Melenhorst J, Beets GL, Breukink SO. Impact of radiotherapy on anorectal function in patients with rectal cancer following a watch and wait programme. Radiother Oncol 2019; 132:79-84 (NKI). 1532. van der Schoot JMS, Fennemann FL, Valente M, Dolen Y, Hagemans IM, Becker AMD, Le Gall CM, van Dalen D, Cevirgel A, van Bruggen JAC, Engelfriet M, Caval T, Bentlage AEH, Fransen MF, Nederend M, Leusen JHW, Heck AJR, Vidarsson G, Figdor CG, Verdoes M, Scheeren FA. Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering. Sci Adv 2019; 5:eaaw1822 (Amsterdam UMC & NKI). 1533. van der Sijde, F, Vietsch, EE, Mustafa, DAM, Besselink, MG, Koerkamp, BG & van Eijck, CHJ . Circulating biomarkers for prediction of objective response to chemotherapy in pancreatic cancer patients. Cancers 2019;11:1: (Amsterdam UMC). 1534. van der Steen, N, Leonetti, A, Keller, K, Dekker, H, Funel, N, Lardon, F, Ruijtenbeek, R, Tiseo, M, Rolfo, C, Pauwels, P, Peters, GJ & Giovannetti, E . Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line. Biochemical Pharmacology 2019;166::128-138. (Amsterdam UMC). 1535. van der Steen, N, Zwaenepoel, K, Mazzaschi, G, A Luirink, R, P Geerke, D, op de Beeck, K, Hermans, C, Tiseo, M, van Schil, P, Lardon, F, Germonpré, P, Rolfo, C, Giovannetti, E, J Peters, G & Pauwels, P . The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies. Molecules 2019;24:: (Amsterdam UMC). 1536. van der Toom, EE, Axelrod, HD, de la Rosette, JJ, de Reijke, TM, Pienta, KJ & Valkenburg, KC . Prostate-specific markers to identify rare prostate cancer cells in liquid biopsies. Nature reviews. Urology 2019;16:1:44743 (Amsterdam UMC). 1537. van der Valk M, Vuijk FA, Putter H, van de Velde CJH, Beets GL, Hilling DE. Disqualification of Neoadjuvant Rectal Score Based on Data of 6596 Patients From the Netherlands Cancer Registry. Clin Colorectal Cancer 2019; 18:e231-e236 (NKI). 1538. van der Valk MJM, Hilling DE, Beets GL. Complete response after neoadjuvant treatment for rectal cancer - Authors' reply. Lancet 2019; 393:1694-5 [Letter] (NKI). 1539. van der Veen GJ, Janssen T, Duijn A, van Kranen S, de Graaf RJ, Wortel G, Wiersma TG, Damen E. A robust volumetric arc therapy planning approach for breast cancer involving the axillary nodes. Med Dosim 2019; 44:183-9 [Letter] (NKI). 1540. van der Velden BHM, Bismeijer T, Canisius S, Loo CE, Lips EH, Wesseling J, Viergever MA, Wessels LFA, Gilhuijs KGA. Are contralateral parenchymal enhancement on dynamic contrast-enhanced MRI and genomic ER-pathway activity in ER-positive/HER2-negative breast cancer related? Eur J Radiol 2019; 121:108705 . (NKI). 1541. van der Velden, DL, Hoes, LR, van der Wijngaart, H, van Berge Henegouwen, JM, van Werkhoven, E, Roepman, P, Schilsky, RL, de Leng, WWJ, Huitema, ADR, Nuijen, B, Nederlof, PM, van Herpen, CML, de Groot, DJA, Devriese, LA, Hoeben, A, de Jonge, MJA, Chalabi, M, Smit, EF, de Langen, AJ, Mehra, N, Labots, M, Kapiteijn, E, Sleijfer, S, Cuppen, E, Verheul, HMW, Gelderblom, H & Voest, EE . The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs. Nature 2019;574:7776:127-131 (Amsterdam UMC & NKI). 1542. van der Velden, J & Fons, G . In response to Rydzewski NR et al. “Role of adjuvant external beam radiotherapy and chemotherapy in one versus two or more node-positive vulvar cancer: A National Cancer Database study”. Radiotherapy and oncology 2019;131::242. (Amsterdam UMC). 1543. van der Velden, J & Mom, CH . Tailoring radicality in early cervical cancer. Gynecologic Oncology 2019;30:1:e30 (Amsterdam UMC). 1544. van der Velden, J & Mom, CH . Tailoring radicality in early cervical cancer: how far can we go?. Journal of gynecologic oncology 2019;30:1:e30 (Amsterdam UMC). 1545. van der Velden, J, Mom, CH, van Lonkhuijzen, L, Tjiong, MY, Westerveld, H & Fons, G . Analysis of isolated loco-regional recurrence rate in intermediate risk early cervical cancer after a type C2 radical hysterectomy without adjuvant radiotherapy. International journal of gynecological cancer 2019;29:5:874-878 (Amsterdam UMC). 1546. van der Velden, S, Braat, MNGJA, Labeur, TA, Scholten, MV, van Delden, OM, Bennink, RJ, de Jong, HWAM & Lam, MGEH . A pilot study on hepatobiliary scintigraphy to monitor regional liver function in 90Y radioembolization. Journal of nuclear medicine 2019;60:10:1430-1436 (Amsterdam UMC). 1547. van der Vorst, MJDL, Neefjes, ECW, Toffoli, EC, Oosterling-Jansen, JEW, Vergeer, MR, Leemans, CR, Kooistra, MP, Voortman, J & Verheul, HMW . Incidence and risk factors for acute kidney injury in head and neck cancer patients treated with concurrent chemoradiation with high-dose cisplatin. BMC Cancer 2019;19:1: (Amsterdam UMC). 1548. van der Waal, I . Oral leukoplakia: A diagnostic challenge for clinicians and pathologists. Oral Diseases 2019;25:1:348-349 (Amsterdam UMC). 1549. van der Wagen L, Janssen J, Raijmakers R, Petersen E, de Witte M, de Jong N, Bellido M, Meijer E, Bar B, Boelens. J. J(NKI). 1550. van der Wal JE, Sgaramella N, Norberg Spaak L, Zborayova K, Nylander K. High podoplanin and low E- cadherin levels correlate with better prognosis in adenoid cystic carcinoma. Clin Exp Dent Res 2019; 5:350-5 (NKI). 1551. van der Weele, P, Breeuwsma, M, Donken, R, van Logchem, E, van Marm-Wattimena, N, de Melker, H, Meijer, CJLM & King, AJ . Effect of the bivalent HPV vaccine on viral load of vaccine and non- vaccine HPV types in incident clearing and persistent infections in young Dutch females. PLoS ONE 2019;14:3: (Amsterdam UMC). 1552. van der Weele, P, King, AJ, Meijer, CJLM & Steenbergen, RDM . HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variant. PAPILLOMAVIRUS RESEARCH 2019;7::168-172. (Amsterdam UMC). 1553. van der Weide RH, de Wit E. Developing landscapes: genome architecture during early embryogenesis. Curr Opin Genet Dev 2019; 55:39-45 (NKI). 1554. van der Wel, MJ, Coleman, HG, Bergman, JJGHM, Jansen, M & Meijer, SL . Histopathologist features predictive of diagnostic concordance at expert level among a large international sample of pathologists diagnosing Barrett's dysplasia using digital pathology. Gut 2019 (Amsterdam UMC). 1555. van der Wel, MJ, Klaver, E, Duits, LC, Pouw, RE, Seldenrijk, CA, Offerhaus, GJA, Visser, M, ten Kate, FJW, Biermann, K, Brosens, LAA, Doukas, M, Huysentruyt, C, Karrenbeld, A, Kats-Ugurlu, G, van der Laan, JS, van Lijnschoten, G, Moll, FCP, Ooms, AHAG, Tijssen, JG, Bergman, JJGHM & Meijer, SL . Adherence to pre-set benchmark quality criteria to qualify as expert assessor of dysplasia in Barrett’s esophagus biopsies – towards digital review of Barrett’s esophagus. United European gastroenterology journal 2019;7:7:889-896 (Amsterdam UMC). 1556. van der Werf LR, Kok NFM, Buis CI, Grunhagen DJ, Hoogwater FJH, Swijnenburg RJ, den Dulk M, Dejong KCHC, Klaase JM, Dutch Hepato Biliary Audit Group. , (Collaborators 18), Prevoo W. Implementation and first results of a mandatory, nationwide audit on liver surgery(Amsterdam UMC & NKI). 1557. van der Werf LR, Voeten SC, van Loe CMM, Karthaus EG, Wouters MWJM, Prins HA. Data verification of nationwide clinical quality registries. BJS Open 2019; 3:857-64 (NKI). 1558. van der Werf LR, Wassenaar E, de Niet A, Lalezari F, Braam HJ, van Ramshorst B, Nederend J, de Hingh I, Kok NFM, Aalbers AGJ. The impact of radiological retroperitoneal lymphadenopathy on survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases. Eur J Surg Oncol 2019; 45:376-82 (NKI). 1559. van der Werf LR, Wijnhoven BPL, Fransen LFC, van Sandick JW, Nieuwenhuijzen GAP, Busweiler LAD, van Hillegersberg R, Wouters MWJM, Luyer MDP, van Berge Henegouwen MI. A National Cohort Study Evaluating the Association Between Short-term Outcomes and Long-term Survival After Esophageal and Gastric Cancer Surgery. Ann Surg 2019; 270:868-76 (Amsterdam UMC & NKI). 1560. van der Werf, LR, Cords, C, Arntz, I, Belt, EJT, Cherepanin, IM, Coene, P-PLO, van der Harst, E, Heisterkamp, J, Langenhoff, BS, Lamme, B, van Berge Henegouwen, MI, Lagarde, SM & Wijnhoven, BPL . Population-Based Study on Risk Factors for Tumor-Positive Resection Margins in Patients with Gastric Cancer. Annals of surgical oncology 2019;26:7:2222-2233 (Amsterdam UMC). 1561. van der Werf, LR, Eshuis, WJ, Draaisma, WA, van Etten, B, Gisbertz, SS, van der Harst, E, Liem, MSL, Lemmens, VEPP, Wijnhoven, BPL, Besselink, MG, van Berge Henegouwen, MI & on behalf of the Dutch Upper Gastrointestinal Cancer Audit (DUCA) group. . Nationwide Outcome of Gastrectomy with En-Bloc Partial Pancreatectomy for Gastric Cancer. Journal of Gastrointestinal Surgery 2019;23:: (Amsterdam UMC). 1562. van der Willik KD, Fani L, Rizopoulos D, Licher S, Fest J, Schagen SB, Ikram MK, Ikram MA. Balance between innate versus adaptive immune system and the risk of dementia: a population-based cohort study. J Neuroinflammation 2019; 16:68 (NKI). 1563. van der Zee, RP, Richel, O, van Noesel, CJM, Novianti, PW, Ciocanea-Teodorescu, I, van Splunter, AP, Duin, S, van den Berk, GEL, Meijer, CJLM, Quint, WGV, de Vries, HJC, Prins, JM & Steenbergen, RDM . Host Cell Deoxyribonucleic Acid Methylation Markers for the Detection of High-grade Anal Intraepithelial Neoplasia and Anal Cancer. Clinical Infectious Diseases 2019;68:7:1110-1117 (Amsterdam UMC). 1564. van Dessel LF, van Riet J, Smits M, Zhu Y, Hamberg P, van der Heijden MS, Bergman AM, van Oort J, de Wit R, Voest EE, Steeghs N, Yamaguchi TN, Livingstone J, Boutros PC, Martens JWM, Sleijfer S, Cuppen E, Zwart W, van de Werken HJG, Mehra N, Lolkema MP. The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact. Nat Commun 2019; 10:5251 (NKI). 1565. van Deudekom FJ, van der Velden LA, Zijl WH, Schimberg AS, Langeveld AP, Slingerland M, Blauw GJ, Mooijaart SP. Geriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study. Head Neck 2019; 41:2477-83 (NKI). 1566. van Diessen, J, de Ruysscher, D, Sonke, J-J, Damen, E, Sikorska, K, Reymen, B, van Elmpt, W, Westman, G, Fredberg Persson, G, Dieleman, E, Bjorkestrand, H, Faivre-Finn, C & Belderbos, J . The acute and late toxicity results of a randomized phase II dose-escalation trial in non-small cell lung cancer (PET-boost trial). Radiotherapy and oncology 2019;131::166-173. (Amsterdam UMC & NKI). 1567. van Dijk N, Funt SA, Blank CU, Powles T, Rosenberg JE, van der Heijden MS. The Cancer Immunogram as a Framework for Personalized Immunotherapy in Urothelial Cancer. Eur Urol 2019; 75:435-44 (NKI). 1568. van Dijk-Lokkart, EM, Steur, LMH, Braam, KI, Veening, MA, Huisman, J, Takken, T, Bierings, M, Merks, JH, van den Heuvel-Eibrink, MM, Kaspers, GJL, van Dulmen-den Broeder, E & van Litsenburg, RRL . Longitudinal development of cancer-related fatigue and physical activity in childhood cancer patients. Pediatric blood & cancer 2019 (Amsterdam UMC). 1569. van Dinther, D, Lopez Venegas, M, Veninga, H, Olesek, K, Hoogterp, L, Revet, M, Ambrosini, M, Kalay, H, Stöckl, J, van Kooyk, Y & den Haan, JMM . Activation of CD8⁺ T Cell Responses after Melanoma Antigen Targeting to CD169⁺ Antigen Presenting Cells in Mice and Humans. Cancers (Basel) 2019;11:2: (Amsterdam UMC). 1570. van Dongen, JM, Persoon, S, Jongeneel, G, Bosmans, JE, Kersten, MJ, Brug, J, Nollet, F, Chinapaw, MJM & Buffart, LM . Long-term effectiveness and cost-effectiveness of an 18-week supervised exercise program in patients treated with autologous stem cell transplantation: results from the EXIST study. Journal of cancer survivorship 2019;13:4:558-569 (Amsterdam UMC). 1571. van Eden WJ, Kok NFM, Snaebjornsson P, Jozwiak K, Woensdregt K, Bottenberg PD, Boot H, Aalbers AGJ. Factors influencing long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei originating from appendiceal neoplasms. BJS Open 2019; 3:376-86 (NKI). 1572. van Eijk M, Boosman RJ, Schinkel AH, Huitema ADR, Beijnen JH. Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes. Cancer Chemother Pharmacol 2019; 84:487-99 (NKI). 1573. van Es, SC, van der Vegt, B, Bensch, F, Gerritse, S, van Helden, EJ, Boon, E, Angus, L, Overbosch, J, Menke-van der Houven van Oordt, CW, Verheul, HM, van Herpen, CML, Jager, A, Oosting, SF, de Vries, EGE & Schröder, CP . Decalcification of Breast Cancer Bone Metastases with EDTA Does Not Affect ER, PR, and HER2 Results. American Journal of Surgical Pathology 2019;43:10:1355-1360 (Amsterdam UMC). 1574. van Gaalen J, Maas RPPW, Ippel EF, Elting MW, van Spaendonck-Zwarts KY, Vermeer S, Verschuuren- Bemelmans C, Timmann D, van de Warrenburg BP. Abnormal eyeblink conditioning is an early marker of cerebellar dysfunction in preclinical SCA3 mutation carriers. Exp Brain Res 2019; 237:427- 33 (NKI). 1575. van Galen, LS, Vedder, D, Boeije, T, Jansen, W, Mullaart-Jansen, NE, van der Peet, DL, So, RKL & Nanayakkara, PWB . Different perspectives on predictability and preventability of surgical readmissions. Journal of Surgical Research 2019;237::95-105 (Amsterdam UMC). 1576. van Groningen JT, Marang-van de Mheen PJ, Henneman D, Beets GL, Wouters MWJM. Surgeon perceived most important factors to achieve the best hospital performance on colorectal cancer surgery: a Dutch modified Delphi method. BMJ Open 2019; 9:e025304 (NKI). 1577. van Groningen, T, Akogul, N, Westerhout, EM, Chan, A, Hasselt, NE, Zwijnenburg, DA, Broekmans, M, Stroeken, P, Haneveld, F, Hooijer, GKJ, Savci-Heijink, CD, Lakeman, A, Volckmann, R, van Sluis, P, Valentijn, LJ, Koster, J, Versteeg, R & van Nes, J . A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma. Nature communications 2019;10:1: (Amsterdam UMC). 1578. van Halsema, EE & van Hooft, JE . Bevacizumab in patients treated with palliative colonic stent placement: Is it safe?. Gastrointestinal endoscopy 2019;90:1:125-126 (Amsterdam UMC). 1579. van Harten, AM, Buijze, M, van der Mast, R, Rooimans, MA, Martens-de Kemp, SR, Bachas, C, Brink, A, Stigter-van Walsum, M, Wolthuis, RMF & Brakenhoff, RH . Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death. Oncogenesis 2019;8:7: (Amsterdam UMC). 1580. van Harten, AM, Poell, JB, Buijze, M, Brink, A, Wells, SI, René Leemans, C, Wolthuis, RMF & Brakenhoff, RH . Characterization of a head and neck cancer-derived cell line panel confirms the distinct TP53-proficient copy number-silent subclass. Oral Oncology 2019;98::53-61. (Amsterdam UMC). 1581. van Helden, EJ, Angus, L, Menke-van der Houven van Oordt, CW, Heideman, DAM, Boon, E, van Es, SC, Radema, SA, van Herpen, CML, de Groot, DJA, de Vries, EGE, Jansen, MPHM, Sleijfer, S & Verheul, HMW . RAS and BRAF mutations in cell-free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue-tested RAS wild-type advanced colorectal cancer. Molecular oncology 2019;13:11:2361-2374 (Amsterdam UMC). 1582. van Hellemond I, Smorenburg CH, Peer PGM, Swinkels ACP, Seynaeve CM, van der Sangen MJC, Kroep JR, De Graaf H, Honkoop AH, Erdkamp FLG, van den Berkmortel FWPJ, de Boer M, de Roos WK, Linn SC, Imholz ALT, Tjan-Heijnen VCG. Assessment and Management of Bone Health in Women with Early Breast Cancer Receiving Endocrine Treatment in the DATA Study. Int J Cancer 2019; 145:1325-33 (NKI). 1583. van Hellemond I, Vriens IJH, Peer PGM, Swinkels ACP, Smorenburg CH, Seynaeve CM, van der Sangen MJC, Kroep JR, De Graaf H, Honkoop AH, Erdkamp FLG, van den Berkmortel FWPJ, de Boer M, de Roos WK, Linn SC, Imholz ALT, Tjan-Heijnen VCG. Efficacy of Anastrozole after Tamoxifen in Early Breast Cancer Patients with Chemotherapy-Induced Ovarian Function Failure. Int J Cancer 2019; 145:274-83 (NKI). 1584. van Hemelrijck, M, Sparano, F, Josephs, D, Sprangers, M, Cottone, F & Efficace, F . Patient-reported outcomes in randomised clinical trials of bladder cancer: an updated systematic review. BMC urology 2019;19:1:86 (Amsterdam UMC). 1585. van Herpen CML, Agarwala SS, Hauschild A, Berking C, Beck JT, Schadendorf D, Jansen R, Queirolo P, Ascierto PA, Blank CU, Heinrich MC, Pal RR, Derti A, Antona V, Nauwelaerts H, Zubel A, Dummer R. Biomarker results from a phase II study of MEK1/2 inhibitor binimetinib (MEK162) in patients with advanced. Oncotarget 2019; 10:1850-9 (NKI). 1586. van Hilst, J, Korrel, M, de Rooij, T, Lof, S, Busch, ORC, Groot Koerkamp, B, Kooby, DA, van Dieren, S, Besselink, MGH & Abu Hilal, M . Oncologic outcomes of minimally invasive versus open distal pancreatectomy for pancreatic ductal adenocarcinoma: A systematic review and meta-analysis.. European journal of surgical oncology 2019;45:5:719-727 (Amsterdam UMC). 1587. van Hilst, J, Strating, EA, de Rooij, T, Daams, F, Festen, S, Groot Koerkamp, B, Klaase, JM, Luyer, M, Dijkgraaf, MG, Besselink, MG, van Santvoort, HC, de Boer, MT, Boerma, D, van den Boezem, PB, van Dam, RM, Dejong, CH, van Duyn, EB, van Eijck, CH, Gerhards, MF, de Hingh, IH, Kazemier, G, de Kleine, RH, van Laarhoven, CJ, Patijn, GA, Steenvoorde, P, Suker, M, Hilal, MA & on behalf of the Dutch Pancreatic Cancer Group and LEOPARD trial collaborators . Costs and quality of life in a randomized trial comparing minimally invasive and open distal pancreatectomy (LEOPARD trial). British Journal of Surgery 2019;106:7:910-921 (Amsterdam UMC). 1588. van Hoppe S, Jamalpoor A, Rood JJM, Wagenaar E, Sparidans RW, Beijnen JH, Schinkel AH. Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (Breast Cancer Resistance Protein). Pharmacol Res 2019; 146:104297 (NKI). 1589. van Houdt WJ, Raut CP, Bonvalot S, Swallow CJ, Haas R, Gronchi A. New research strategies in retroperitoneal sarcoma. The case of TARPSWG, STRASS and RESAR: making progress through collaboration(NKI). 1590. van Huijgevoort, NCM, del Chiaro, M, Wolfgang, CL, van Hooft, JE & Besselink, MG . Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines. Nature reviews. Gastroenterology & hepatology 2019;16:11:676-689 (Amsterdam UMC). 1591. van Kalmthout, L, Braat, A, Lam, M, van Leeuwaarde, R, Krijger, G, Ververs, T, Mehra, N, Bins, A, Hunting, J & de Keizer, B . First Experience With 177Lu-PSMA-617 Therapy for Advanced Prostate Cancer in the Netherlands. Clinical nuclear medicine 2019;44:6:446-451 (Amsterdam UMC). 1592. van Kesteren, Z, van der Horst, A, Gurney-Champion, OJ, Bones, I, Tekelenburg, D, Alderliesten, T, van Tienhoven, G, Klaassen, R, van Laarhoven, HWM & Bel, A . A novel amplitude binning strategy to handle irregular breathing during 4DMRI acquisition: Improved imaging for radiotherapy purposes. Radiation oncology (London, England) 2019;14:1: (Amsterdam UMC). 1593. van Keulen, S, Nishio, N, Fakurnejad, S, van den Berg, NS, Lu, G, Birkeland, A, Martin, BA, Forouzanfar, T, Colevas, AD & Rosenthal, EL . Intraoperative Tumor Assessment Using Real-Time Molecular Imaging in Head and Neck Cancer Patients. Journal of the American College of Surgeons 2019;229:6:560-567 (Amsterdam UMC & NKI). 1594. van Keulen, S, van den Berg, NS, Nishio, N, Birkeland, A, Zhou, Q, Lu, G, Wang, H-W, Middendorf, L, Forouzanfar, T, Martin, BA, Colevas, AD & Rosenthal, EL . Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma. Oral Oncology 2019;88::58- 65 (Amsterdam UMC). 1595. van Kooten, JAMC, Maurice-Stam, H, Schouten, AYN, van Vuurden, DG, Granzen, B, Gidding, C, de Ruiter, MA, van Litsenburg, RRL & Grootenhuis, MA . High occurrence of sleep problems in survivors of a childhood brain tumor with neurocognitive complaints: The association with psychosocial and behavioral executive functioning. Pediatric Blood and Cancer 2019;66::e27947 (Amsterdam UMC). 1596. van Lanschot, MCJ, Carvalho, B, Rausch, C, Snaebjornsson, P, van Engeland, M, Kuipers, EJ, Stoker, J, Tutein Nolthenius, CJ, Dekker, E & Meijer, GA . Molecular profiling of longitudinally observed small colorectal polyps: A cohort study. EBioMedicine 2019;39::292-300 (Amsterdam UMC & NKI). 1597. van Lanschot, MCJ, van Leerdam, ME, Lansdorp-Vogelaar, I, Doets, S, Nagtegaal, ID, Schreurs, HW, van der Hulst, RWM, Carvalho, B, Dekker, E & van Berkel, A-M . Yield of Surveillance Colonoscopies 1 Year After Curative Surgical Colorectal Cancer Resections. Clinical gastroenterology and hepatology 2019;17:11:2285-2293 (Amsterdam UMC & NKI). 1598. van Leerdam ME, Roos VH, van Hooft JE, Balaguer F, Dekker E, Kaminski MF, Latchford A, Neumann H, Ricciardiello L, Rupinska M, Saurin JC, Tanis PJ, Wagner A, Jover R, Pellise M. Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2019; 51:1082-93 (NKI). 1599. van Leerdam, ME, Roos, VH, van Hooft, JE, Dekker, E, Jover, R, Kaminski, MF, Latchford, A, Neumann, H, Pellisé, M, Saurin, J-C, Tanis, PJ, Wagner, A, Balaguer, F & Ricciardiello, L . Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2019;51:9:877-895 (Amsterdam UMC & NKI). 1600. van Leerdam, ME, van Leerdam, ME, Roos, VH, van Hooft, JE, Dekker, E, Balaguer, F, Pellisé, M, Balaguer, F, Pellisé, M, Kaminski, MF, Rupińska, M, Kaminski, MF, Rupińska, M, Kaminski, MF, Latchford, A, Latchford, A & Neumann, H . Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2019;51:11:1082-1093 (Amsterdam UMC). 1601. van Leeuwen FWB, van Oosterom MN, Meershoek P, van Leeuwen PJ, Berliner C, van der Poel HG, Graefen M, Maurer T. Minimal-Invasive Robot-Assisted Image-Guided Resection of Prostate-Specific Membrane Antigen-Positive Lymph Nodes in Recurrent Prostate Cancer. Clin Nucl Med 2019; 44:580-1 (NKI). 1602. van Leeuwen FWB, Winter A, van der Poel HG, Eiber M, Suardi N, Graefen M, Wawroschek F, Maurer T. Technologies for image-guided surgery for managing lymphatic metastases in prostate cancer. Nat Rev Urol 2019; 16:159-71 (NKI). 1603. van Leeuwen PJ, Donswijk M, Nandurkar R, Stricker P, Ho B, Heijmink S, Wit EMK, Tillier C, van Muilenkom E, Nguyen Q, van der Poel HG, Emmett L. 68Ga PSMA PET/CT predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate and high-risk prostate cancer. BJU Int 2019; 124:62-8 (NKI). 1604. van Lent LGG, Stoel NK, van Weert JCM, van Gurp J, de Jonge MJA, Lolkema MP, Gort EH, Pulleman SM, Oomen-de HE, Hasselaar J, van der Rijt CCD. Realizing better doctor-patient dialogue about choices in palliative care and early phase clinical trial participation: towards an online value clarification tool (OnVaCT). BMC Palliat Care 2019; 18:106 (NKI). 1605. van Lierop, AH, Bisschop, PH, Boelen, A, van Eeden, S, Engelman, AF, Nieveen van Dijkum, EJ & Klümpen, H-J . Hypercalcaemia due to a calcitriol-producing neuroendocrine tumour. Journal of surgical case reports 2019;2019:12:rjz346 (Amsterdam UMC). 1606. van Loevezijn AA, Bartels SAL, van Duijnhoven FH, Heemsbergen WD, Bosma SCJ, Elkhuizen PHM, Donswijk ML, Rutgers EJT, Oldenburg HSA, Vrancken Peeters MTFD, van der Ploeg I. Internal Mammary Chain Sentinel Nodes in Early-Stage Breast Cancer Patients: Toward Selective Removal. Ann Surg Oncol 2019; 26:945-53 (NKI). 1607. van Loevezijn AA, van der Ploeg I. ASO Author Reflections: A Reappraisal of Internal Mammary Chain Sentinel Node Biopsy in Breast Cancer Patients: Recommendations for Clinical Practice. Ann Surg Oncol 2019; 26(Suppl 3):565-6 (NKI). 1608. van Lonkhuizen PJC, Klaver KM, Wefel JS, Sitskoorn MM, Schagen SB, Gehring K. Interventions for cognitive problems in adults with brain cancer: A narrative review. Eur J Cancer Care (Engl) 2019; 28:e13088 (13 pp) (NKI). 1609. van Loon Y, Hendriksma M, Heijnen BJ, van de Kamp V, Hakkesteegt MM, Bohringer S, Langeveld TPM, de Jong MA, Klop WMC, Baatenburg de Jong RJ, Sjogren EV. Voice outcome after unilateral ELS type III or bilateral type II resections for T1-T2 glottic carcinoma: Results after 1 year. Head Neck 2019; 41:1638-47 (NKI). 1610. van Maaren MC, de Munck L, Strobbe LJ, Sonke GS, Westenend PJ, Smidt ML, Poortmans PM, Siesling S. 10-year recurrence rates for breast cancer subtypes in the Netherlands: A large population-based study. Int J Cancer 2019; 144:263-72 (NKI). 1611. van Mackelenbergh, MG, Stroes, CI, Spijker, R, van Eijck, CHJ, Wilmink, JW, Bijlsma, MF & van Laarhoven, HWM . Clinical trials targeting the stroma in pancreatic cancer: A systematic review and meta-analysis. Cancers 2019;11:5: (Amsterdam UMC). 1612. van Muijen, P, Schellart, AJM, Duijts, SFA & van der Beek, AJ . The mediating role of coping between self-reported health complaints and functional limitations, self-assessed work ability and work status of long-term sick-listed cancer survivors. European Journal of Cancer Care 2019;28:1: (Amsterdam UMC). 1613. van Munster, SN, Pouw, RE & Bergman, JJGHM . Randomized studies for Barrett's ablation: just because we can doesn't mean we should. Gastrointestinal endoscopy 2019;89:4:690-692 (Amsterdam UMC). 1614. van Neerven, SM & Vermeulen, L . The interplay between intrinsic and extrinsic Wnt signaling in controlling intestinal transformation. Differentiation; research in biological diversity 2019;108::17- 23. (Amsterdam UMC). 1615. van Nieuwenhuizen, D, Slot, KM, Klein, M, Verbaan, D, Aliaga, ES, Heimans, JJ, Vandertop, WP, Peerdeman, SM & Reijneveld, JC . The association between preoperative edema and postoperative cognitive functioning and health-related quality of life in WHO grade I meningioma patients. Acta Neurochirurgica 2019;161:3:579-588 (Amsterdam UMC). 1616. van Nuland M, Bergman AM, Rosing H, de Vries N, Huitema ADR, Beijnen JH. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy 2019; 39:1137-45 (NKI). 1617. van Nuland M, Groenland S, Bergman AM, Rotmans JI, Rosing H, Beijnen JH, Huitema ADR. Plasma Levels of Enzalutamide and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer Undergoing Hemodialysis. Clin Genitourin Cancer 2019; 17:e383-e386 (NKI). 1618. van Nuland M, Janssen JM, van Hoek B, Rosing H, Beijnen JH, Bergman AM. Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration- resistant Prostate Cancer With a Hepatic Transplant. Clin Genitourin Cancer 2019; 17:e893-e896 (NKI). 1619. van Nuland M, Rosing H, Huitema ADR, Beijnen JH. Predictive Value of Microdose Pharmacokinetics. Clin Pharmacokinet 2019; 58:1221-36 (NKI). 1620. van Nuland M, Venekamp N, de Vries N, de Jong KAM, Rosing H, Beijnen JH. Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1106-1107:26-34 (NKI). 1621. van Nuland M, Venekamp N, Wouters WME, van Rossum HH, Rosing H, Beijnen JH. LC-MS/MS assay for the quantification of testosterone, dihydrotestosterone, androstenedione, cortisol and prednisone in plasma from castrated prostate cancer patients treated with abiraterone acetate or enzalutamide. J Pharm Biomed Anal 2019; 170:161-8 (Amsterdam UMC & NKI). 1622. van Oers, M, Smolej, L, Petrini, M, Offner, F, Grosicki, S, Levin, M-D, Davis, J, Banerjee, H, Stefanelli, T, Hoever, P & Geisler, C . Ofatumumab maintenance prolongs progression-free survival in relapsed chronic lymphocytic leukemia: final analysis of the PROLONG study. Blood cancer journal 2019;9:12: (Amsterdam UMC). 1623. van Ommen, C, Iersel, L, Lequin, M, Janssens, G, Clement, S, Boot, A, Caron, H, Claahsen-van der Grinten, H, Granzen, B, Han, K, Michiels, E, van Trotsenburg, A, Vandertop, W, van Vuurden, D, Kremer, L, Schouten-van Meeteren, A & van Santen, H . MON-458 Radiological Alterations Of The Hypothalamic-pituitary Region After Craniospinal Irradiation For Medulloblastoma During Childhood.. Journal of the Endocrine Society 2019;3:Supplement_1: (Amsterdam UMC). 1624. van Oorschot R, Hansen M, Koornneef JM, Marneth AE, Bergevoet SM, van Bergen MGJM, van Alphen FPJ, van der Zwaan C, Martens JHA, Vermeulen M, Jansen PWTC, Baltissen MPA, Laros-van Gorkom BAP, Janssen H, Jansen JH, von Lindern M, Meijer AB, van den Akker E, van der Reijden BA. Molecular mechanisms of bleeding disorder-associated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets. Haematologica 2019; 104:1460-72 (NKI). 1625. van Oosterom MN, Rietbergen DDD, Welling MM, van der Poel HG, Maurer T, van Leeuwen FWB. Recent advances in nuclear and hybrid detection modalities for image-guided surgery. Expert Rev Med Devices 2019; 16:711-34 (NKI). 1626. van Osch FHM, Nekeman D, Aaronson NK, Billingham LJ, James ND, Cheng KK, Bryan RT, Zeegers MP. Patients choose certainty over burden in bladder cancer surveillance. World J Urol 2019; 37:2747-53 (NKI). 1627. van Pul KM, Vuylsteke RJCL, van de Ven R, Te Velde EA, Rutgers EJT, van den Tol PM, Stockmann HBAC, de Gruijl TD. Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node. J Immunother Cancer 2019; 7:133 (14 pp) (Amsterdam UMC & NKI). 1628. van Putten, M, Lemmens, VEPP, van Laarhoven, HWM, Pruijt, HFM, Nieuwenhuijzen, GAP & Verhoeven, RHA . Poor compliance with perioperative chemotherapy for resectable gastric cancer and its impact on survival. European journal of surgical oncology 2019;45:10:1926-1933 (Amsterdam UMC). 1629. van Rijswijk, AS, Hagens, ERC, van der Peet, DL, van Berge Henegouwen, MI & Gisbertz, SS . Differences in Esophageal Cancer Surgery in Terms of Surgical Approach and Extent of Lymphadenectomy: Findings of an International Survey. Annals of surgical oncology 2019;26:7:2063- 2072 (Amsterdam UMC). 1630. van Roessel, S, Mackay, TM, Tol, JAMG, van Delden, OM, van Lienden, KP, Nio, CY, Phoa, SSKS, Fockens, P, van Hooft, JE, Verheij, J, Wilmink, JW, van Gulik, TM, Gouma, DJ, Busch, OR & Besselink, MG . Impact of expanding indications on surgical and oncological outcome in 1434 consecutive pancreatoduodenectomies. HPB: The official journal of the International Hepato Pancreato Biliary Association 2019;21:7:865-875 (Amsterdam UMC). 1631. van Rooij, W, Dahele, M, Ribeiro Brandao, H, Delaney, AR, Slotman, BJ & Verbakel, WF . Deep Learning-Based Delineation of Head and Neck Organs at Risk: Geometric and Dosimetric Evaluation. International Journal of Radiation Oncology Biology Physics 2019;104:3:677-684 (Amsterdam UMC). 1632. van Rossum HH, van den Broek D. Design and implementation of quality control plans that integrate moving average and internal quality control: incorporating the best of both worlds. Clin Chem Lab Med 2019; 57:1329-38 (NKI). 1633. van Rossum HH. Moving average quality control: principles, practical application and future perspectives. Clin Chem Lab Med 2019; 57:773-82 (NKI). 1634. van Sandwijk, MS, Al Arashi, D, van de Hare, FM, van der Torren, JMR, Kersten, MJ, Bijlsma, JA, Berge, IJMT & Bemelman, FJ . Fatigue, Anxiety, Depression and Quality of Life in Kidney Transplant Recipients, Haemodialysis Patients, Patients with a Haematological Malignancy and Healthy Controls. Nephrology, dialysis, transplantation 2019;34:5:833-838 (Amsterdam UMC). 1635. van Schie MA, van Houdt PJ, Ghobadi G, Pos FJ, Walraven I, de Boer HCJ, van den Berg CAT, Smeenk RJ, Kerkmeijer LGW, van der Heide UA. Quantitative MRI Changes During Weekly Ultra- Hypofractionated Prostate Cancer Radiotherapy With Integrated Boost. Front Oncol 2019; 9:1264 (NKI). 1636. van Seijen M, Lips EH, Thompson AM, Nik-Zainal S, Futreal A, Hwang ES, Verschuur E, Lane J, Jonkers J, Rea DW, Wesseling J. Ductal carcinoma in situ: to treat or not to treat, that is the question. Br J Cancer 2019; 121:285-92 (NKI). 1637. van Seijen, M, Brcic, L, Gonzales, AN, Sansano, I, Bendek, M, Brcic, I, Lissenberg-Witte, B, Korkmaz, HI, Geiger, T, Kammler, R, Stahel, R, Thunnissen, E & On behalf of ETOP . Impact of delayed and prolonged fixation on the evaluation of immunohistochemical staining on lung carcinoma resection specimen. Virchows Archiv 2019;475:2:191-199 (Amsterdam UMC). 1638. Van Senten, JR, Bebelman, MP, Fan, TS, Heukers, R, Bergkamp, ND, Van Gasselt, P, Langemeijer, EV, Slinger, E, Lagerweij, T, Rahbar, A, Van Walsum, MS, Maussang, D, Leurs, R, Musters, RJP, Van Dongen, GAMS, Söderberg-Nauclér, C, Würdinger, T, Siderius, M & Smit, MJ . The human cytomegalovirus-encoded G protein- coupled receptor UL33 exhibits oncomodulatory properties. Journal of Biological Chemistry 2019;294:44:16297-16308 (Amsterdam UMC). 1639. van Son MJ, Lock MTWT, Peters M, Fransen van de Putte EE, Meijer RP. Treating benign ureteroenteric strictures: 27-year experience comparing endourological techniques with open surgical approach. World J Urol 2019; 37:1217-33 (NKI). 1640. van Spronsen, MF, Westers, TM, Lissenberg-Witte, BI, Wondergem, M, Ossenkoppele, GJ & van de Loosdrecht, AA . The non-erythroid myeloblast count rule in myelodysplastic syndromes. Haematologica 2019;104:12:E547-E550 (Amsterdam UMC). 1641. van Steensel B, Furlong EEM. The role of transcription in shaping the spatial organization of the genome. Nat Rev Mol Cell Biol 2019; 20:327-37 (NKI). 1642. Van Strien, J, Guerrero-Castillo, S, Chatzispyrou, IA, Houtkooper, RH, Brandt, U & Huynen, MA . COmplexome Profiling ALignment (COPAL) reveals remodeling of mitochondrial protein complexes in Barth syndrome. Bioinformatics (Oxford, England) 2019;35:17:3083-3091 (Amsterdam UMC). 1643. van 't Sant I, van Eden WJ, Engbersen MP, Kok NFM, Woensdregt K, Lambregts DMJ, Shanmuganathan S, Beets-Tan RGH, Aalbers AGJ, Lahaye MJ. Diffusion-weighted MRI assessment of the peritoneal cancer index before cytoreductive surgery. Br J Surg 2019; 106:491-8 (NKI). 1644. van Veenendaal LM, Madu MF, Tesselaar MET, Verhoef CK, Grunhagen DJ, van Akkooi ACJ. Reply to: Letter re: Efficacy of isolated limb perfusion (ILP) in patients with Merkel cell carcinoma: A multicenter experience. Eur J Surg Oncol 2019; 45:1122-3 [Letter] (NKI). 1645. van Veldhuisen, E, van den Oord, C, Brada, LJ, Walma, MS, Vogel, JA, Wilmink, JW, del Chiaro, M, van Lienden, KP, Meijerink, MR, van Tienhoven, G, Hackert, T, Wolfgang, CL, van Santvoort, H, Koerkamp, BG, Busch, OR, Quintus Molenaar, I, van Eijck, CH & Besselink, MG . Locally advanced pancreatic cancer: Work-up, staging, and local intervention strategies. Cancers 2019;11:7: (Amsterdam UMC). 1646. van Vliet LM, Francke AL, Meijers MC, Westendorp J, Hoffstadt H, Evers AWM, van der Wall E, de Jong P, Peerdeman KJ, Stouthard J, van Dulmen S. The Use of Expectancy and Empathy When Communicating With Patients With Advanced Breast Cancer; an Observational Study of Clinician- Patient Consultations. Front Psychiatry 2019; 10:464 (14 pp) (Amsterdam UMC & NKI). 1647. van Vliet, LM, de Veer, AJE, Raijmakers, NJH & Francke, A . Is Information Provision about Benefits and Risks of Treatment Options Associated with Receiving Person-Centered Care?: A Survey among Incurably Ill Cancer Patients. Journal of Palliative Medicine 2019;22:7:797-803 (Amsterdam UMC). 1648. van Waalwijk van Doorn-Khosrovani, SB, Pisters-van Roy, A, van Saase, L, van der Graaff, M, Gijzen, J, Sleijfer, S, Hoes, LR, van Berge Henegouwen, JM, van der Wijngaart, H, van der Velden, DL, van Werkhoven, E, Retel, VP, van Harten, WH, Huitema, ADR, Timmers, L, Gelderblom, H, Verheul, HMW & Voest, EE . Personalised reimbursement: A risk-sharing model for biomarker-driven treatment of rare subgroups of cancer patients. Annals of Oncology 2019;30:5:663-665 (Amsterdam UMC & NKI). 1649. van Waart, H, Buffart, LM, Stuiver, MM, van Harten, WH, Sonke, GS & Aaronson, NK . Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer. Supportive Care in Cancer 2019 (Amsterdam UMC). 1650. van Walree I, van Soolingen NJ, Hamaker ME, Smorenburg CH, Louwers JA, van Huis-Tanja LH. Treatment decision-making in elderly women with ovarian cancer: an age-based comparison. Int J Gynecol Cancer 2019; 29:158-65 (NKI). 1651. van Weert LTCM, Buurstede JC, Sips HCM, Vettorazzi S, Mol IM, Hartmann J, Prekovic S, Zwart W, Schmidt MV, Roozendaal B, Tuckermann JP, Sarabdjitsingh RA, Meijer OC. Identification of mineralocorticoid receptor target genes in the mouse hippocampus. J Neuroendocrinol 2019; 31:e12735 (12 pp) (NKI). 1652. van Wezel, EM, van Zogchel, LMJ, van Wijk, J, Timmerman, I, Vo, N-K, Zappeij-Kannegieter, L, deCarolis, B, Simon, T, van Noesel, M, Molenaar, JJ, van Groningen, T, Versteeg, R, Caron, HN, van der Schoot, CE, Koster, J, van Nes, J & Tytgat, G . Mesenchymal Neuroblastoma Cells Are Undetected by Current mRNA Marker Panels: The Development of a Specific Neuroblastoma Mesenchymal Minimal Residual Disease Panel. JCO Precision Oncology 2019 (Amsterdam UMC). 1653. van Workum, F, Stenstra, MHBC, Berkelmans, GHK, Slaman, AE, van Berge Henegouwen, MI, Gisbertz, SS, van den Wildenberg, FJH, Polat, F, Irino, T, Nilsson, M, Nieuwenhuijzen, GAP, Luyer, MD, Adang, EM, Hannink, G, Rovers, MM & Rosman, C . Learning Curve and Associated Morbidity of Minimally Invasive Esophagectomy: A Retrospective Multicenter Study. Annals of surgery 2019;269:1:88-94 (Amsterdam UMC). 1654. Vänskä, S, Bogaards, JA, Auranen, K, Lehtinen, M & Berkhof, J . Fast approximate computation of cervical cancer screening outcomes by a deterministic multiple-type HPV progression model. Mathematical Biosciences 2019; 309, 92-106. >.org/10.1016/j.mbs.2019.01.006:: (Amsterdam UMC). 1655. Vardy JL, Stouten-Kemperman MM, Pond G, Booth CM, Rourke SB, Dhillon HM, Dodd A, Crawley A, Tannock IF. A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer. Brain Imaging Behav 2019; 13:15-26 (NKI). 1656. Vasdev N, Zargar H, Noel JP, Veeratterapillay R, Fairey AS, Mertens LS, Dinney CP, Mir MC, Krabbe LM, Cookson MS, Jacobsen NE, Gandhi NM, Griffin J, Montgomery JS, Yu EY, Xylinas E, Campain NJ, Kassouf W, Dall'Era MA, Seah JA, Ercole CE, Horenblas S, Sridhar SS, McGrath JS, Aning J, Shariat SF, Wright JL, Morgan TM, Bivalacqua TJ, North S, Barocas DA, Lotan Y, Grivas P, Stephenson AJ, Shah JB, van Rhijn BW, Daneshmand S, Spiess PE, Holzbeierlein JM, Thorpe A, Black PC. Concomitant CIS on TURBT does not impact oncological outcomes in patients treated with neoadjuvant or induction chemotherapy followed by radical cystectomy. World J Urol 2019; 37:165-72 (NKI). 1657. Veld, JV, Amelung, FJ, Borstlap, WAA, Eise van Halsema, E, Consten, ECJ, Siersema, PD, ter Borg, F, Silvester van der Zaag, E, Fockens, P, Bemelman, WA, Elise van Hooft, J, Tanis, PJ & Dutch Snapshot Research Group . Changes in Management of Left-Sided Obstructive Colon Cancer: National Practice and Guideline Implementation. Journal of the National Comprehensive Cancer Network 2019;17:12:1512-1520 (Amsterdam UMC & NKI). 1658. Veld, JV, Amelung, FJ, Borstlap, WAA, van Halsema, EE, Consten, ECJ, Siersema, PD, ter Borg, F, van der Zaag, ES, de Wilt, JHW, Fockens, P, Bemelman, WA, van Hooft, JE & Tanis, PJ . Comparison of Decompressing Stoma vs Stent as a Bridge to Surgery for Left-Sided Obstructive Colon Cancer. JAMA surgery 2019 (Amsterdam UMC & NKI). 1659. Veldhuijzen van Zanten, SEM, de Witt Hamer, PC & van Dongen, GAMS . Brain access of monoclonal antibodies as imaged and quantified by 89Zr-antibody PET: Perspectives for treatment of brain diseases. Journal of Nuclear Medicine 2019;60:5:615-616 (Amsterdam UMC). 1660. Veldwijk, J, Groothuis-Oudshoorn, CGM, Kihlbom, U, Langenskiöld, S, Dekker, E, Kallenberg, FGJ, de Wit, GA & Lambooij, MS . How psychological distance of a study sample in discrete choice experiments affects preference measurement: A colorectal cancer screening case study. Patient preference and adherence 2019; 13, 273-282. >.org/10.2147/PPA.S180994:: (Amsterdam UMC). 1661. Veltcamp Helbach, M, Koedam, TWA, Knol, JJ, Velthuis, S, Bonjer, HJ, Tuynman, JB & Sietses, C . Quality of life after rectal cancer surgery: differences between laparoscopic and transanal total mesorectal excision. Surgical Endoscopy 2019;33:1:79-87 (Amsterdam UMC & NKI). 1662. Verbakel, WFAR, Doornaert, PAH, Raaijmakers, CPJ, Bos, LJ, Essers, M, van de Kamer, JB, Dahele, M, Terhaard, CHJ & Kaanders, JHAM . Targeted Intervention to Improve the Quality of Head and Neck Radiation Therapy Treatment Planning in the Netherlands: Short and Long-Term Impact. International Journal of Radiation Oncology Biology Physics 2019;105:3:514-524 (Amsterdam UMC & NKI). 1663. Verbeek JGE, Atema V, Mewes JC, van Leeuwen M, Oldenburg HSA, van Beurden M, Hunter MS, van Harten WH, Aaronson NK, Retel VP. Cost-utility, cost-effectiveness, and budget impact of Internet- based cognitive behavioral therapy for breast cancer survivors with treatment-induced menopausal symptoms. Breast Cancer Res Treat 2019; 178:573-85 (NKI). 1664. Verboom MC, Gelderblom H, Kerst JM, Steeghs N, Reyners AKL, Sleijfer S, van der Graaf WTA, van den Hout WB. Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients. Sarcoma 2019; 2019:3234205 (NKI). 1665. Verboom MC, Kloth JSL, Swen JJ, Sleijfer S, Reyners AKL, Steeghs N, Mathijssen RHJ, Gelderblom H, Guchelaar HJ. Genetic polymorphisms in ABCG2 and CYP1A2 are associated with imatinib dose reduction in patients treated for gastrointestinal stromal tumors. Pharmacogenomics J 2019; 19:473- 9 (NKI). 1666. Verburg, N, Koopman, T, Yaqub, M, Hoekstra, OS, Lammertsma, AA, Schwarte, LA, Barkhof, F, Pouwels, PJW, Heimans, JJ, Reijneveld, JC, Rozemuller, AJM, Vandertop, WP, Wesseling, P, Boellaard, R & de Witt Hamer, PC . Direct comparison of [11C] choline and [18F] FET PET to detect glioma infiltration. EJNMMI Research 2019;9:1:57 (Amsterdam UMC). 1667. Verdonck-de Leeuw, IM, Jansen, F, Brakenhoff, RH, Langendijk, JA, Takes, R, Terhaard, CHJ, de Jong, RJB, Smit, JH & Leemans, CR . Advancing interdisciplinary research in head and neck cancer through a multicenter longitudinal prospective cohort study: The NETherlands QUality of life and BIomedical Cohort (NET-QUBIC) data warehouse and biobank. BMC Cancer 2019;19:1: (Amsterdam UMC). 1668. Verheijen RB, Thijssen B, Atrafi F, Schellens JHM, Rosing H, de Vries N, Beijnen JH, Mathijssen RHJ, Steeghs N, Huitema ADR. Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling. J Chromatogr B Analyt Technol Biomed Life Sci 2019; 1104:234-9 (NKI). 1669. Verheijen RB, van der Biessen DAJ, Hotte SJ, Siu LL, Spreafico A, de Jonge MJA, Pronk LC, De Vos FYFL, Schnell D, Hirte HW, Steeghs N, Lolkema MP. Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520. Target Oncol 2019; 14:67-74 (NKI). 1670. Verhoeff, SR, van Es, SC, Boon, E, van Helden, E, Angus, L, Elias, SG, Oosting, SF, Aarntzen, EH, Brouwers, AH, Kwee, TC, Heskamp, S, Hoekstra, OS, Verheul, H, van der Veldt, AAM, de Vries, EGE, Boerman, OC, van der Graaf, WTA, Oyen, WJG & van Herpen, CML . Lesion detection by [89Zr]Zr- DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:9:1931-1939 (Amsterdam UMC). 1671. Verly, IRN, Leen, R, Meinsma, JR, Hooijer, GKJ, Savci-Heijink, CD, van Nes, J, Broekmans, M, Wanders, RJA, van Kuilenburg, ABP & Tytgat, GAM . Catecholamine excretion profiles identify clinical subgroups of neuroblastoma patients. European journal of cancer (Oxford, England 2019; 111, 21- 29. >.org/10.1016/j.ejca.2019.01.014:: (Amsterdam UMC). 1672. Vermeulen RFM, Korse CM, Kenter GG, Brood-van Zanten MMA, van Beurden M. Safety of hormone replacement therapy following risk-reducing salpingo-oophorectomy: systematic review of literature and guidelines. Climacteric 2019; 22:352-60 (NKI). 1673. Vermeulen, BD, Reijm, AN, van der Bogt, RD, van Hooft, JE, Spaander, MCW & Siersema, PD . Through-the-scope placement of a fully covered metal stent for palliation of malignant dysphagia: a prospective cohort study (with video). Gastrointestinal endoscopy 2019;90:6:972-979 (Amsterdam UMC). 1674. Vernooij, RWM, van Oort, I, de Reijke, TM & Aben, KKH . Nationwide treatment patterns and survival of older patients with prostate cancer. Journal of geriatric oncology 2019;10:2:252-258 (Amsterdam UMC). 1675. Versluis J, Valk G, van Rossum H, Tesselaar M. Non-islet cell tumour hypoglycaemia in a patient with a well-differentiated gastric neuroendocrine tumour. BMJ Case Rep 2019; 12:e231069 (NKI). 1676. Verver D, van der Veldt AAM, van Akkooi ACJ, Verhoef C, Grunhagen DJ, Louwman WJ. Reply to: The real-world outcome of metastatic melanoma: unknown primary versus known cutaneous. Int J Cancer 2019; 145:2175-3176 [Letter] (NKI). 1677. Verver D, van Klaveren D, Franke V, van Akkooi ACJ, Rutkowski P, Keilholz U, Eggermont AMM, Nijsten T, Grunhagen DJ, Verhoef C. Development and validation of a nomogram to predict recurrence and melanoma-specific mortality in patients with negative sentinel lymph nodes. Br J Surg 2019; 106:217-25 (NKI). 1678. Verweij, FJ, Revenu, C, Arras, G, Dingli, F, Loew, D, Pegtel, DM, Follain, G, Allio, G, Goetz, JG, Zimmermann, P, Herbomel, P, Del Bene, F, Raposo, G & van Niel, G . Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo. Developmental Cell 2019;48:4:573-589 (Amsterdam UMC). 1679. Vieira B, Demirtas D, van de Kamer B, Hans EW, van Harten W. Improving workflow control in radiotherapy using discrete-event simulation. BMC Med Inform Decis Mak 2019; 19:199 (NKI). 1680. Villafanez F, Garcia IA, Carbajosa S, Pansa MF, Mansilla S, Llorens MC, Angiolini V, Guantay L, Jacobs H, Madauss KP, Gloger I, Gottifredi V, Bocco JL, Soria G. AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress. Oncogene 2019; 38:4310-24 (NKI). 1681. Vincenten, JPL, van Essen, HF, Lissenberg-Witte, BI, Bulkmans, NWJ, Krijgsman, O, Sie, D, Eijk, PP, Smit, EF, Ylstra, B & Thunnissen, E . Clonality analysis of pulmonary tumors by genome-wide copy number profiling. PLoS ONE 2019;14:10: (Amsterdam UMC & NKI). 1682. Vis, AN, van der Poel, HG, Ruiter, AEC, Hu, JC, Tewari, AK, Rocco, B, Patel, VR, Razdan, S & Nieuwenhuijzen, JA . Posterior, Anterior, and Periurethral Surgical Reconstruction of Urinary Continence Mechanisms in Robot-assisted Radical Prostatectomy: A Description and Video Compilation of Commonly Performed Surgical Techniques. European Urology 2019;76:6:814-822 (Amsterdam UMC & NKI). 1683. Visser LL, Elshof LE, Van de Vijver K, Groen EJ, Almekinders MM, Sanders J, Bierman C, Peters D, Hofland I, Broeks A, van Leeuwen FE, Rutgers EJT, Schmidt MK, Schaapveld M, Lips EH, Wesseling J. Discordant Marker Expression Between Invasive Breast Carcinoma and Corresponding Synchronous and Preceding DCIS. Am J Surg Pathol 2019; 43:1574-82 (NKI). 1684. Visser LL, Groen EJ, van Leeuwen FE, Lips EH, Schmidt MK, Wesseling J. Predictors of an Invasive Breast Cancer Recurrence after DCIS: A Systematic Review and Meta-analyses. Cancer Epidemiol Biomarkers Prev 2019; 28:835-45 (NKI). 1685. Visser M, Muller DMJ, van Duijn RJM, Smits M, Verburg N, Hendriks EJ, Nabuurs RJA, Bot JCJ, Eijgelaar RS, Witte M, van Herk MB, Barkhof F, De Witt Hamer PC, de Munck JC. Inter-rater agreement in glioma segmentations on longitudinal MRI. Neuroimage Clin 2019; 22:101727 (11 pp) (NKI). 1686. Visser, J, de Boer, P, Crama, KF, van Kesteren, Z, Rasch, CRN, Stalpers, LJA & Bel, A . Dosimetric comparison of library of plans and online MRI-guided radiotherapy of cervical cancer in the presence of intrafraction anatomical changes. Radiation oncology (London, England) 2019;14:1: (Amsterdam UMC). 1687. Visser, M, Müller, DMJ, van Duijn, RJM, Smits, M, Verburg, N, Hendriks, EJ, Nabuurs, RJA, Bot, JCJ, Eijgelaar, RS, Witte, M, van Herk, MB, Barkhof, F, de Witt Hamer, PC & de Munck, JC . Inter-rater agreement in glioma segmentations on longitudinal MRI. NeuroImage: Clinical 2019; 22, 101727. >.org/10.1016/j.nicl.2019.101727, >.org/10.1016/j.nicl.2019.101727:: (Amsterdam UMC). 1688. Visser, NCM, van der Putten, LJM, van Egerschot, A, van de Vijver, KK, Santacana, M, Bronsert, P, Hirschfeld, M, Colas, E, Gil-Moreno, A, Garcia, A, Mancebo, G, Alameda, F, Krakstad, C, Tangen, IL, Huvila, J, Schrauwen, S, Koskas, M, Walker, F, Weinberger, V, Minar, L, Hausnerova, J, Snijders, MPLM, van den Berg-van Erp, S, Matias-Guiu, X, Trovik, J, Amant, F, Massuger, LFAG, Bulten, J & Pijnenborg, JMA . Addition of IMP3 to L1CAM for discrimination between low- and high-grade endometrial carcinomas: a European Network for Individualised Treatment of Endometrial Cancer collaboration study. Human pathology 2019; 89, 90-98. >.org/10.1016/j.humpath.2019.04.014:: (Amsterdam UMC). 1689. Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi- Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F. Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma. EMBO J 2019; 38:e101564 (NKI). 1690. Vlenterie M, Oyen WJG, Steeghs N, Desar IME, Verheijen RB, Koenen AM, Grootjans W, de Geus-Oei LF, van Erp NP, van der Graaf WT. Early Metabolic Response as a Predictor of Treatment Outcome in Patients With Metastatic Soft Tissue Sarcomas. Anticancer Res 2019; 39:1309-16 (NKI). 1691. Vleugels, JLA, Hassan, C, Senore, C, Cassoni, P, Baron, JA, Rex, DK, Ponugoti, PL, Pellise, M, Parejo, S, Bessa, X, Arnau-Collell, C, Kaminski, MF, Bugajski, M, Wieszczy, P, Kuipers, EJ, Melson, J, Ma, KH, Holman, R, Dekker, E & Pohl, H . Diminutive Polyps With Advanced Histologic Features Do Not Increase Risk for Metachronous Advanced Colon Neoplasia. Gastroenterology 2019;156:3:623-634 (Amsterdam UMC). 1692. Vleugels, JLA, Hazewinkel, Y, Dijkgraaf, MGW, Koens, L, Fockens, P & Dekker, E . Optical diagnosis expanded to small polyps: Post-hoc analysis of diagnostic performance in a prospective multicenter study. Endoscopy 2019;51:3:244-252 (Amsterdam UMC). 1693. Vleugels, JLA, van Neerven, SM, van Leerdam, ME, Wanders, LK, de Wit, M, Carvalho, B, Delis-van Diemen, PM, Kallenberg, FGJ, Vermeulen, L, Beliën, JA, East, JE, Meijer, GA & Dekker, E . CD31- positive microvessel density within adenomas of Lynch Syndrome patients is similar compared to adenomas of non-Lynch patients. Endoscopy International Open 2019;7:5:E701-E707 (Amsterdam UMC & NKI). 1694. Voeten SC, Arends AJ, Wouters MWJM, Blom BJ, Heetveld MJ, Slee-Valentijn MS, Krijnen P, Schipper IB, Hegeman JHH. The Dutch Hip Fracture Audit: evaluation of the quality of multidisciplinary hip fracture care in the Netherlands. Arch Osteoporos 2019; 14:28 (NKI). 1695. Voeten SC, van Bodegom-Vos L, Hegeman JH, Wouters MWJM, Krijnen P, Schipper IB. Hospital staff participation in a national hip fracture audit: facilitators and barriers. Arch Osteoporos 2019; 14:110 (NKI). 1696. Voeten, DM, den Bakker, CM, Heineman, DJ, Ket, JCF, Daams, F & van der Peet, DL . Definitive Chemoradiotherapy Versus Trimodality Therapy for Resectable Oesophageal Carcinoma: Meta- analyses and Systematic Review of Literature. World Journal of Surgery 2019;43:5:1271-1285 (Amsterdam UMC). 1697. Vogel C, Ziegelmuller B, Ljungberg B, Bensalah K, Bex A, Canfield S, Giles RH, Hora M, Kuczyk MA, Merseburger AS, Powles T, Albiges L, Stewart F, Volpe A, Graser A, Schlemmer M, Yuan C, Lam T, Staehler M. Imaging in Suspected Renal-Cell Carcinoma: Systematic Review. Clin Genitourin Cancer 2019; 17:e345-e355 (NKI). 1698. Vogel, JA, van Veldhuisen, E, Alles, LK, Busch, OR, Dijk, F, van Gulik, TM, Huijzer, GM, Besselink, MG, van Lienden, KP & Verheij, J . Time-Dependent Impact of Irreversible Electroporation on Pathology and Ablation Size in the Porcine Liver: A 24-Hour Experimental Study. Technology in cancer research & treatment 2019; 18, 1533033819876899. >.org/10.1177/1533033819876899:: (Amsterdam UMC). 1699. Vogels, R, Baumhoer, D, van Gorp, J, Eijkelenboom, A, Verdijk, M, van Cleef, P, Bloemena, E, Slootweg, PJ, Lohman, B, Debiec-Rychter, M & Flucke, U . Clear Cell Odontogenic Carcinoma. Head and neck pathology 2019;13:2:225-230 (Amsterdam UMC). 1700. Vollenbrock SE, Nowee ME, Voncken FEM, Kotte ANTJ, Goense L, van Rossum PSN, van Lier ALHM, Heijmink SW, Bartels-Rutten A, Wessels FJ, Aleman BMP, Dewit L, Kerkmeijer LGW, Jansen EPM, Intven M, Lips IM, Meijer GJ, Nijkamp J. Gross Tumor Delineation in Esophageal Cancer on MRI Compared With (18)F-FDG-PET/CT. Adv Radiat Oncol 2019; 4:596-604 (NKI). 1701. Vollenbrock, SE, Voncken, FEM, van Dieren, JM, Lambregts, DMJ, Maas, M, Meijer, GJ, Goense, L, Mook, S, Hartemink, KJ, Snaebjornsson, P, ter Beek, LC, Verheij, M, Aleman, BMP, Beets-Tan, RGH & Bartels-Rutten, A . Diagnostic performance of MRI for assessment of response to neoadjuvant chemoradiotherapy in oesophageal cancer. British Journal of Surgery 2019;106:5:596-605 (Amsterdam UMC & NKI). 1702. Voltin, C-A, Mettler, J, Boellaard, R, Kuhnert, G, Dietlein, M, Borchmann, P, Drzezga, A & Kobe, C . Quantitative assessment of 18F-FDG PET in patients with Hodgkin lymphoma. Nuclear Medicine Communications 2019;40:3:249-257 (Amsterdam UMC). 1703. Voorwerk, L, Slagter, M, Horlings, HM, Sikorska, K, van de Vijver, KK, de Maaker, M, Nederlof, I, Kluin, RJC, Warren, S, Ong, S, Wiersma, TG, Russell, NS, Lalezari, F, Schouten, PC, Bakker, NAM, Ketelaars, SLC, Peters, D, Lange, CAH, van Werkhoven, E, van Tinteren, H, Mandjes, IAM, Kemper, I, Onderwater, S, Chalabi, M, Wilgenhof, S, Haanen, JBAG, Salgado, R, de Visser, KE, Sonke, GS, Wessels, LFA, Linn, SC, Schumacher, TN, Blank, CU & Kok, M . Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial (Nature Medicine, (2019), 25, 6, (920-928), 10.1038/s41591-019-0432-4). Nature medicine 2019;25:7:1175 (Amsterdam UMC & NKI). 1704. Vorselaars, WMCM, van Beek, D-J, Postma, EL, Spiering, W, Borel Rinkes, IHM, Valk, GD, Vriens, MR & International CONNsortium Study Group . Validation of the Aldosteronoma Resolution Score Within Current Clinical Practice. World Journal of Surgery 2019; 43. >.org/10.1007/s00268-019- 05074-z:: (Amsterdam UMC & NKI). 1705. Vos M, Blaauwgeers HGT, Ho VKY, van Houdt WJ, van der Hage JA, Been LB, Bonenkamp JJ, Bemelmans MHA, van Dalen T, Haas RL, Grunhagen DJ, Verhoef C. Increased survival of non low- grade and deep-seated soft tissue sarcoma after surgical management in high-volume hospitals: a nationwide study from the Netherlands. Eur J Cancer 2019; 110:98-106 (NKI). 1706. Vos M, Sleijfer S, Litiere S, Touati N, Duffaud F, van der Graaf WT, Gelderblom H. Association of pazopanib-induced toxicities with outcome of patients with advanced soft tissue sarcoma; a retrospective analysis based on the European Organisation for Research and Treatment of Cancer (EORTC) 62043 and 62072 clinical trials. Acta Oncol 2019; 58:872-9 (NKI). 1707. Vos, DRN, Jansen, I, Lucas, M, Paine, MRL, de Boer, OJ, Meijer, SL, Savci-Heijink, CD, Marquering, HA, de Bruin, DM, Heeren, RMA, Ellis, SR & Balluff, B . Strategies for managing multi-patient 3D mass spectrometry imaging data. Journal of proteomics 2019; 193, 184-191. >.org/10.1016/j.jprot.2018.10.008:: (Amsterdam UMC). 1708. Voskuilen CS, Bosschieter J, van Werkhoven E, Hendricksen K, Vis AN, Witteveen T, Pieters BR, Burger M, Bex A, van der Poel HG, Moonen LM, Horenblas S, Nieuwenhuijzen JA, van Rhijn BWG. Long-term survival and complications following bladder-preserving brachytherapy in patients with cT1-T2 bladder cancer. Radiother Oncol 2019; 141:130-6 (Amsterdam UMC & NKI). 1709. Voskuilen CS, Oo HZ, Genitsch V, Smit LA, Vidal A, Meneses M, Necchi A, Colecchia M, Xylinas E, Fontugne J, Sibony M, Roupret M, Lenfant L, Cote JF, Buser L, Saba K, Furrer MA, van der Heijden MS, Daugaard M, Black PC, van Rhijn BWG, Hendricksen K, Poyet C, Seiler R. Multicenter Validation of Histopathologic Tumor Regression Grade After Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Carcinoma. Am J Surg Pathol 2019; 43:1600-10 (NKI). 1710. Voskuilen CS, van der Heijden MS, van Rhijn BWG. Re: Multicenter Prospective Phase II Trial of Neoadjuvant Dose-dense Gemcitabine Plus Cisplatin in Patients with Muscle-invasive Bladder Cancer. Eur Urol 2019; 76:870-1 (NKI). 1711. Voskuilen L, Mazzoli V, Oudeman J, Balm AJM, van der Heijden F, Froeling M, de Win MML, Strijkers GJ, Smeele LE, Nederveen AJ. Crossing muscle fibers of the human tongue resolved in vivo using constrained spherical deconvolution. J Magn Reson Imaging 2019; 50:95-105 (NKI). 1712. Vossen, DM, Verhagen, CVM, van der Heijden, M, Essers, PBM, Bartelink, H, Verheij, M, Wessels, LFA, van den Brekel, MWM & Vens, C . Genetic factors associated with a poor outcome in head and neck cancer patients receiving definitive chemoradiotherapy. Cancers (Basel) 2019;11:4: (Amsterdam UMC & NKI). 1713. Vrancken Peeters MTFD. Management of the axilla after neoadjuvant chemotherapy for breast cancer. Br J Surg 2019; 106:1571-3 (NKI). 1714. Vredevoogd DW, Kuilman T, Ligtenberg MA, Boshuizen J, Stecker KE, de Bruijn B, Krijgsman O, Huang X, Kenski JCN, Lacroix R, Mezzadra R, Gomez-Eerland R, Yildiz M, Dagidir I, Apriamashvili G, Zandhuis N, van der Noort V, Visser NL, Blank CU, Altelaar M, Schumacher TN, Peeper DS. Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold. Cell 2019; 178:585-99(NKI). 1715. Vromans RD, van Eenbergen MC, Pauws SC, Geleijnse G, van der Poel HG, van de Poll-Franse.L.V., Krahmer EJ. Communicative aspects of decision aids for localized prostate cancer treatment - A systematic review. Urol Oncol 2019; 37:409-29 (NKI). 1716. Wagner AD, Grabsch HI, Mauer M, Marreaud S, Caballero C, Thuss-Patience P, Mueller L, Elme A, Moehler MH, Martens U, Kang YK, Rha SY, Cats A, Tokunaga M, Lordick F. EORTC-1203-GI. BMC Cancer 2019; 19:494 (NKI). 1717. Wagner AD, Oertelt-Prigione S, Adjei A, Buclin T, Cristina V, Csajka C, Coukos G, Dafni U, Dotto GP, Ducreux M, Fellay J, Haanen J, Hocquelet A, Klinge I, Lemmens V, Letsch A, Mauer M, Moehler M, Peters S, Ozdemir BC . Gender Medicine and Oncology: Report and consensus of an ESMO Workshop. Ann Oncol 2019; 30:1914-24 (NKI). 1718. Waissi F, Kist JW, Lodewijk L, de Wit AG, van der Hage JA, van Dalen T, de Keizer B, Valk GD, Borel Rinkes I, Vriens MR. Fast-track Radioiodine Ablation Therapy After Thyroidectomy Reduces Sick Leave in Patients With Differentiated Thyroid Cancer (FASTHYNA Trial). Clin Nucl Med 2019; 44:272-5 (NKI). 1719. Wakeford R, Azizova T, Dorr W, Garnier-Laplace J, Hauptmann M, Ozasa K, Rajaraman P, Sakai K, Salomaa S, Sokolnikov M, Stram D, Sun Q, Wojcik A, Woloschak G, Bouffler S, Grosche B, Kai M, Little MP, Shore RE, Walsh L, Ruhm W. The dose and dose-rate effectiveness factor (DDREF). Health Phys 2019; 116:96-9 (NKI). 1720. Walraven, JEW, Desar, IME, Hoeven van der, JJM, Aben, KKH, Hillegersberg van, R, Rasch, CRN, Lemmens, VEPP & Verhoeven, RHA . Analysis of 105.000 patients with cancer: have they been discussed in oncologic multidisciplinary team meetings? A nationwide population-based study in the Netherlands. European journal of cancer (Oxford, England 2019; 121, 85-93. >.org/10.1016/j.ejca.2019.08.007:: (Amsterdam UMC). 1721. Walsh L, Haley KE, Moran B, Mooney B, Tarrant F, Madden SF, Di Grande A, Fan Y, Das S, Rueda OM, Dowling CM, Vareslija D, Chin SF, Linn SC, Young LS, Jirstrom K, Crown J, Bernards R, Caldas C, Gallagher WM, O'Connor DP, Ni CT. BET inhibition as a rational therapeutic strategy for invasive lobular breast cancer. Clin Cancer Res 2019; 25:7139-50 (NKI). 1722. Wang C, Vegna S, Jin H, Benedict B, Lieftink C, Ramirez C, de Oliveira RL, Morris B, Gadiot J, Wang W, du Chatinier A, Wang L, Gao D, Evers B, Jin G, Xue Z, Schepers A, Jochems F, Sanchez AM, Mainardi S, Te Riele H, Beijersbergen RL, Qin W, Akkari L, Bernards R. Inducing and exploiting vulnerabilities for the treatment of liver cancer. Nature 2019; 574:268-72 (NKI). 1723. Wang J, Gan C, Retmana IA, Sparidans RW, Li W, Lebre MC, Beijnen JH, Schinkel AH. P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice. Int J Pharm 2019; 556:172-80 (NKI). 1724. Wang VE, Xue JY, Frederick DT, Cao Y, Lin E, Wilson C, Urisman A, Carbone DP, Bernards R, Lito P, Settleman J, McCormick F, Flaherty KT. Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF- Driven Tumors Through Autocrine FGFR Pathway Activation. Clin Cancer Res 2019; 25:7202-17 (NKI). 1725. Wang, Z, Balgobind, BV, Virgolin, M, van Dijk, IWEM, Wiersma, J, Ronckers, CCM, Bosman, PAN, Bel, A & Alderliesten, T . How do patient characteristics and anatomical features correlate to accuracy of organ dose reconstruction for Wilms' tumor radiation treatment plans when using a surrogate patient's CT scan?. Journal of radiological protection 2019;39:2:598-619 (Amsterdam UMC). 1726. Wardill, HR, Secombe, KR, Bryant, RV, Hazenberg, MD & Costello, SP . Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients. EBioMedicine 2019; 44, 730-740. >.org/10.1016/j.ebiom.2019.03.070:: (Amsterdam UMC). 1727. Warmerdam, DO & Wolthuis, RMF . Keeping ribosomal DNA intact: a repeating challenge. Chromosome Research 2019;27:43862:57-72 (Amsterdam UMC). 1728. Wasmann, KATGM, Klaver, CEL, van der Bilt, JDW, van Dieren, S, Nagtegaal, ID, Punt, CJA, van Ramshorst, B, Wolthuis, AM, de Wilt, JHW, D’hoore, A, van Santvoort, HC & Tanis, PJ . Laparoscopic surgery facilitates administration of adjuvant chemotherapy in locally advanced colon cancer: Propensity score analyses. Cancer Management and Research 2019; 11, 7141-7157. >.org/10.2147/CMAR.S205906:: (Amsterdam UMC). 1729. Wedman, J, Pruim, J, van der Putten, L, Hoekstra, OS, de Bree, R, van Dijk, BAC & van der Laan, BFAM . Is C-11 Methionine PET an alternative to 18-F FDG-PET for identifying recurrent laryngeal cancer after radiotherapy?. Clinical Otolaryngology 2019;44:2:124-130 (Amsterdam UMC). 1730. Weeda, VB, Aronson, DC, Verheij, J & Lamers, WH . Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patients. Pediatric blood & cancer 2019;66:2: (Amsterdam UMC). 1731. Weidema ME, Flucke UE, van der Graaf WTA, Ho VKY, Hillebrandt-Roeffen MHS, Versleijen-Jonkers YMH, Husson O, Desar IME. Prognostic Factors in a Large Nationwide Cohort of Histologically Confirmed Primary and Secondary Angiosarcomas. Cancers (Basel) 2019; 11:1780 (11 pp) (NKI). 1732. Wellenstein MD, Coffelt SB, Duits DEM, van Miltenburg MH, Slagter M, de Rink I, Henneman L, Kas SM, Prekovic S, Hau CS, Vrijland K, Drenth AP, de Korte-Grimmerink R, Schut E, van der Heijden I, Zwart W, Wessels LFA, Schumacher TN, Jonkers J, de Visser KE. Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis. Nature 2019; 572:538-42 (NKI). 1733. Wellenstein MD, de Visser KE. Fatty Acids Corrupt Neutrophils in Cancer. Cancer Cell 2019; 35:827-9 (NKI). 1734. Werter, IM, Huijts, CM, Lougheed, SM, Hamberg, P, Polee, MB, Tascilar, M, Los, M, Haanen, JBAG, Helgason, HH, Verheul, HM, de Gruijl, TD, van der Vliet, HJ & Dutch WIN-O Consortium . Metronomic cyclophosphamide attenuates mTOR-mediated expansion of regulatory T cells, but does not impact clinical outcome in patients with metastatic renal cell cancer treated with everolimus. Cancer Immunology and Immunotherapy 2019; 68. >.org/10.1007/s00262-019-02313-z:: (Amsterdam UMC & NKI). 1735. Wesseling, P . The ABCs of molecular diagnostic testing of CNS tumors: acceptance, benefits, costs. Neuro-Oncology 2019;21:5:559-561 (Amsterdam UMC). 1736. Wester, R, van der Holt, B, Asselbergs, E, Zweegman, S, Kersten, MJ, Vellenga, E, van Marwijk Kooy, M, de Weerdt, O, Minnema, M, Lonergan, S, Palumbo, A, Lokhorst, H, Broijl, A & Sonneveld, P . Phase II study of carfilzomib, thalidomide, and low-dose dexamethasone as induction and consolidation in newly diagnosed, transplant eligible patients with multiple myeloma; the Carthadex trial. Haematologica 2019;104:11:2265-2273 (Amsterdam UMC). 1737. Westerduin, E, Westerterp, M, Bemelman, WA, Tanis, PJ & van Geloven, AA . Low Hartmann’s procedure or intersphincteric abdominoperineal resection in the primary treatment of low rectal cancer; a survey among surgeons evaluating current practice. Acta chirurgica Belgica 2019;119:2:132-136 (Amsterdam UMC). 1738. Westgeest, HM, Kuppen, MCP, van den Eertwegh, AJM, de Wit, R, Coenen, JLLM, van den Berg, HPP, Mehra, N, van Oort, IM, Fossion, LMCL, Hendriks, MP, Bloemendal, HJ, van de Luijtgaarden, ACM, ten Bokkel Huinink, D, van den Bergh, ACMF, van den Bosch, J, Polee, MB, Weijl, N, Bergman, AM, Uyl-de Groot, CA & Gerritsen, WR . Second-Line Cabazitaxel Treatment in Castration-Resistant Prostate Cancer Clinical Trials Compared to Standard of Care in CAPRI: Observational Study in the Netherlands. Clinical Genitourinary Cancer 2019;17:5:e946-e956 (Amsterdam UMC & NKI). 1739. Wieldraaijer, T, de Meij, M, Zwaard, S, van Weert, H & Wind, J . Introducing a time out consultation with the general practitioner between diagnosis and start of colorectal cancer treatment: Patient- reported outcomes. European journal of cancer care 2019 (Amsterdam UMC). 1740. Wieldraaijer, T, Duineveld, LAM, Bemelman, WA, van Weert, HCPM & Wind, J . Information needs and information seeking behaviour of patients during follow-up of colorectal cancer in the Netherlands. Journal of cancer survivorship 2019;13:4:603-610 (Amsterdam UMC). 1741. Wierzbicka, M, Berkhof, JH & Dikkers, FG . Prophylactic human papilloma virus vaccination in head and neck: Indications and future perspectives. Current Opinion in Otolaryngology and Head and Neck Surgery 2019;27:2:85-90 (Amsterdam UMC). 1742. Wijmans L, Baas P, Sieburgh TE, de Bruin DM, Ghuijs PM, van de Vijver MJ, Bonta PI, Annema JT. Confocal laser endomicroscopy (CLE) as a guidance tool for pleural biopsies in malignant pleural mesothelioma. Chest 2019; 156:754-63 (Amsterdam UMC & NKI). 1743. Wijmans L, Yared J, de Bruin DM, Meijer SL, Baas P, Bonta PI, Annema JT. Needle-based confocal laser endomicroscopy (nCLE) for real-time diagnosing and staging of lung cancer. Eur Respir J 2019; 53:pii: 1801520(Amsterdam UMC & NKI). 1744. Wildeboer, RR, van Sloun, RJG, Huang, P, Wijkstra, H & Mischi, M . 3-D Multi-parametric Contrast- Enhanced Ultrasound for the Prediction of Prostate Cancer. Ultrasound in medicine & biology 2019;45:10:2713-2724 (Amsterdam UMC). 1745. Wildeboer, RR, van Sloun, RJG, Wijkstra, H & Mischi, M . EFSUMB Young Investigator Award 2019. Ultraschall in der Medizin (Stuttgart, Germany 2019;40:4:522-523 (Amsterdam UMC). 1746. Willemien Menke-van der Houven van Oordt, C, McGeoch, A, Bergstrom, M, McSherry, I, Smith, DA, Cleveland, M, Al-Azzam, W, Chen, L, Verheul, H, Hoekstra, OS, Vugts, DJ, Freedman, I, Huisman, M, Matheny, C, van Dongen, G & Zhang, S . Immuno-PET imaging to assess target engagement: Experience from 89Zr-anti-HER3 mAb (GSK2849330) in patients with solid tumors. Journal of Nuclear Medicine 2019;60:7:902-909 (Amsterdam UMC). 1747. Willems SM, Abeln S, Feenstra KA, De Bree R, van der Poel EF, Baatenburg de Jong RJ, Heringa J, van den Brekel MWM. The potential use of big data in oncology. Oral Oncol 2019; 98:8-12 (NKI). 1748. Willemsen, AECAB, Krausz, S, Ligtenberg, MJL, Grünberg, K, Groen, HJM, Voest, EE, Cuppen, EPJG, van Laarhoven, HWM & van Herpen, CML . Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations. British journal of cancer 2019;121:1:34-36 (Amsterdam UMC & NKI). 1749. Willemsen, M, Linkutė, R, Luiten, RM & Matos, TR . Skin-resident memory T cells as a potential new therapeutic target in vitiligo and melanoma. Pigment cell & melanoma research 2019;32:5:612-622 (Amsterdam UMC). 1750. Wind TT, Jalving M, de Haan JJ, de Vries EGE, van Vugt MATM, Reijngoud DJ, van Rijn RS, Haanen JBAG, Blank CU, Hospers GAP, Fehrmann RSN . A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma. Oncoimmunology 2019; 8:1558664 (NKI). 1751. Wink KCJ, Lock S, Rossi M, van Baardwijk A, Belderbos J, De Ruysscher D, Troost EGC. Contact of a tumour with the pleura is not associated with regional recurrence following stereotactic ablative radiotherapy for early stage non-small cell lung cancer. Radiother Oncol 2019; 131:120-6 (NKI). 1752. Wirth, M, Fossati, N, Albers, P, Bangma, C, Brausi, M, Comperat, E, Faithfull, S, Gillessen, S, Jereczek- Fossa, BA, Mastris, K, Mottet, N, Müller, SC, Pieters, B, Ribal, MJ, Sangar, V, Schoots, IG, Smelov, V, Travado, L, Valdagni, R, Wesselmann, S, Wiegel, T & van Poppel, H . The European Prostate Cancer Centres of Excellence: A Novel Proposal from the European Association of Urology Prostate Cancer Centre Consensus Meeting. European urology 2019;76:2:179-186 (Amsterdam UMC). 1753. Wisselink DD, Braakhuis LLF, Gallo G, van Grevenstein WMU, van Dieren S, Kok NFM, de Reuver PR, Tanis PJ, de Hingh, I. Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer. Crit Rev Oncol Hematol 2019; 142:119-29 (NKI). 1754. Wisselink, DD, Braakhuis, LLF, Gallo, G, van Grevenstein, WMU, van Dieren, S, Kok, NFM, de Reuver, PR, Tanis, PJ & de Hingh, IHJT . Systematic review of published literature on oxaliplatin and mitomycin C as chemotherapeutic agents for hyperthermic intraperitoneal chemotherapy in patients with peritoneal metastases from colorectal cancer. Critical reviews in oncology/hematology 2019; 142, 119-129. >.org/10.1016/j.critrevonc.2019.06.014:: (Amsterdam UMC). 1755. Witlox L, Schagen SB, de Ruiter MB, Geerlings MI, Peeters PHM, Koevoets EW, van der Wall E, Stuiver M, Sonke G, Velthuis MJ, Palen JAMV, Jobsen JJ, May AM, Monninkhof EM. Effect of physical exercise on cognitive function and brain measures after chemotherapy in patients with breast cancer (PAM study): protocol of a randomised controlled trial. BMJ Open 2019; 9:e028117 (NKI). 1756. Witlox WJA, Ramaekers BLT, Groen HJM, Dingemans AM, Praag J, Belderbos J, van der Noort V, Van Tinteren H, Joore MA, De Ruysscher DKM. Factors determining the effect of prophylactic cranial irradiation (PCI) in patients with stage-III nonsmall cell lung cancer: exploratory subgroup analyses of the NVALT-11/DLCRG-02 phase-III study. Acta Oncol 2019; 58:1528-31 (NKI). 1757. Witlox WJA, Ramaekers BLT, Joore MA, Dingemans AC, Praag J, Belderbos J, Tissing-Tan C, Herder G, Haitjema T, Ubbels JF, Lagerwaard J, El Sharouni SY, Stigt JA, Smit EF, Van Tinteren H, van der Noort V, Groen HJM, De Ruysscher DKM. Health-related quality of life after prophylactic cranial irradiation for stage III non-small cell lung cancer patients: Results from the NVALT-11/DLCRG-02 phase III study. Radiother Oncol 2019; 144:65-71 (NKI). 1758. Witvliet-van Nierop, JE, de van der Schueren, MAE, Scheffer, HJ, Vroomen, LG, Meijerink, MR, van Bodegraven, AA & Wierdsma, NJ . Exocrine pancreatic and enterocyte function in patients with advanced pancreatic cancer. Clinical Nutrition 2019;38:6:2778-2782 (Amsterdam UMC). 1759. Woestenberg, PJ, Bogaards, JA, King, AJ, Leussink, S, van der Sande, MAB, Hoebe, CJPA, van Benthem, BHB & on behalf of the Medical Microbiological Laboratories and the Public Health Services . Assessment of herd effects among women and heterosexual men after girls-only HPV16/18 vaccination in the Netherlands: A repeated cross-sectional study. International Journal of Cancer 2019;144:11:2718-2727 (Amsterdam UMC). 1760. Wolvers, MDJ, Leensen, MCJ, Groeneveld, IF, Frings-Dresen, MHW & de Boer, AGEM . Longitudinal Associations Between Fatigue and Perceived Work Ability in Cancer Survivors. Journal of occupational rehabilitation 2019;29:3:540-549 (Amsterdam UMC). 1761. Wondergem, M, Jansen, BHE, van der Zant, FM, van der Sluis, TM, Knol, RJJ, van Kalmthout, LWM, Hoekstra, OS, van Moorselaar, RJA, Oprea-Lager, DE & Vis, AN . Early lesion detection with 18F- DCFPyL PET/CT in 248 patients with biochemically recurrent prostate cancer. European Journal of Nuclear Medicine and Molecular Imaging 2019;46:9:1911-1918 (Amsterdam UMC). 1762. Wortel RC, Oomen-de HE, Heemsbergen WD, Pos FJ, Incrocci L. Moderate hypofractionation in intermediate and high risk, localized prostate cancer: Health-related quality of life from the randomized, phase 3 HYPRO trial. Int J Radiat Oncol Biol Phys 2019; 103:823-33 (NKI). 1763. Woudstra, AJ, Smets, EMA, Dekker, E, Broens, THF, Penning, J, Smith, S, McCaffery, K & Fransen, MP. Development and pilot-testing of a colorectal cancer screening decision aid for individuals with varying health literacy levels. Patient education and counseling 2019;102:10:1847-1858 (Amsterdam UMC). 1764. Woudstra, AJ, Smets, EMA, Verdam, MGE & Fransen, MP . The role of health literacy in explaining the relation between educational level and decision making about colorectal cancer screening. International journal of environmental research and public health 2019;16:23: (Amsterdam UMC). 1765. Wujanto, C, Vellayappan, B, Siva, S, Louie, AV, Guckenberger, M, Slotman, BJ, Onishi, H, Nagata, Y, Liu, M & Lo, SS . Stereotactic Body Radiotherapy for Oligometastatic Disease in Non-small Cell Lung Cancer. Frontiers in Oncology 2019; 9, 1219. >.org/10.3389/fonc.2019.01219:: (Amsterdam UMC). 1766. Xue Y, Meehan B, Macdonald E, Venneti S, Wang XQD, Witkowski L, Jelinic P, Kong T, Martinez D, Morin G, Firlit M, Abedini A, Johnson RM, Cencic R, Patibandla J, Chen H, Papadakis AI, Auguste A, de Rink I, Kerkhoven RM, Bertos N, Gotlieb WH, Clarke BA, Leary A, Witcher M, Guiot MC, Pelletier J, Dostie J, Park M, Judkins AR, Hass R, Levine DA, Rak J, Vanderhyden B, Foulkes WD, Huang S. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary. Nat Commun 2019; 10:558 (NKI). 1767. Yadav, KS, Kapse-Mistry, S, Peters, GJ & Mayur, YC . E-drug delivery: a futuristic approach. Drug Discovery Today 2019;24:4:1023-1030 (Amsterdam UMC). 1768. Yang Y, Shu X, Shu XO, Bolla MK, Kweon SS, Cai Q, Michailidou K, Wang Q, Dennis J, Park B, Matsuo K, Kwong A, Park SK, Wu AH, Teo SH, Iwasaki M, Choi JY, Li J, Hartman M, Shen CY, Muir K, Lophatananon A, Li B, Wen W, Gao YT, Xiang YB, Aronson KJ, Spinell JJ, Gago-Dominguez M, John EM, Kurian AW, Chang-Claude J, Chen ST, Dork T, Evans DGR, Schmidt MK, Shin MH, Giles GG, Milne RL, Simard J, Kubo M, Kraft P, Kang D, Easton DF, Zheng W, Long J. Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry. EBioMedicine 2019; 48:203-11 (NKI). 1769. Yang, H, Wang, J, Zhao, M, Zhu, J, Zhang, M, Wang, Z, Gao, Y, Zhu, W & Lu, H . Feasible development of stable HEK293 clones by CRISPR/Cas9-mediated site-specific integration for biopharmaceuticals production. Biotechnology Letters 2019;41:44082:941-950 (Amsterdam UMC). 1770. Yatabe, Y, Dacic, S, Borczuk, AC, Warth, A, Russell, PA, Lantuejoul, S, Beasley, MB, Thunnissen, E, Pelosi, G, Rekhtman, N, Bubendorf, L, Mino-Kenudson, M, Yoshida, A, Geisinger, KR, Noguchi, M, Chirieac, LR, Bolting, J, Chung, J-H, Chou, T-Y, Chen, G, Poleri, C, Lopez-Rios, F, Papotti, M, Sholl, LM, Roden, AC, Travis, WD, Hirsch, FR, Kerr, KM, Tsao, M-S, Nicholson, AG, Wistuba, I & Moreira, AL . Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer. Journal of Thoracic Oncology 2019;14:3:377-407 (Amsterdam UMC). 1771. Yazlovitskaya E, Viquez O, Tu T, De Arcangelis A, Georges-Labouesse E, Sonnenberg A, Pozzi A, Zent R. The laminin binding alpha3 and alpha6 integrins cooperate to promote epithelial cell adhesion and growth. Matrix Biol 2019; 77:101-16 (NKI). 1772. Yu EY, Nekeman D, Aaronson NK, Billingham LJ, James ND, Cheng KK, Bryan RT, Wesselius A, Zeegers MP. Health-Related Quality of Life in Bladder Cancer Patients around the Time of Diagnosis. BJU Int 2019; 124:984-91 (NKI). 1773. Yu, X, van Munster, SN, Zhang, Y, Xue, L, Fleischer, DE, Weusten, BLAM, Lu, N, Dawsey, SSM, Bergman, JJGHM & Wang, G . Durability of radiofrequency ablation for treatment of esophageal squamous cell neoplasia: 5-year follow-up of a treated cohort in China. Gastrointestinal endoscopy 2019;89:4:736-748 (Amsterdam UMC). 1774. Zecha, JAEM, Raber-Durlacher, JE, Laheij, AMGA, Westermann, AM, Epstein, JB, de Lange, J & Smeele, LE . The impact of the oral cavity in febrile neutropenia and infectious complications in patients treated with myelosuppressive chemotherapy. Supportive care in cancer 2019;27:10:3667- 3679 (Amsterdam UMC & NKI). 1775. Zeijlemaker, W, Grob, T, Meijer, R, Hanekamp, D, Kelder, A, Carbaat-Ham, JC, Oussoren-Brockhoff, YJM, Snel, AN, Veldhuizen, D, Scholten, WJ, Maertens, J, Breems, DA, Pabst, T, Manz, MG, van der Velden, VHJ, Slomp, J, Preijers, F, Cloos, J, van de Loosdrecht, AA, Löwenberg, B, Valk, PJM, Jongen- Lavrencic, M, Ossenkoppele, GJ & Schuurhuis, GJ . CD34+CD38− leukemic stem cell frequency to predict outcome in acute myeloid leukemia. Leukemia 2019;33:5:1102-1112 (Amsterdam UMC). 1776. Zeijlemaker, W, Kelder, A, Cloos, J & Schuurhuis, GJ . Immunophenotypic Detection of Measurable Residual (Stem Cell) Disease Using LAIP Approach in Acute Myeloid Leukemia. Current Protocols in Cytometry 2019;91:1: (Amsterdam UMC). 1777. Zelenetz, AD, Salles, G, Mason, KD, Casulo, C, le Gouill, S, Sehn, LH, Tilly, H, Cartron, G, Chamuleau, MED, Goy, A, Tam, CS, Lugtenburg, PJ, Petrich, AM, Sinha, A, Samineni, D, Herter, S, Ingalla, E, Szafer- Glusman, E, Klein, C, Sampath, D, Kornacker, M, Mobasher, M & Morschhauser, F . Venetoclax plus R- or G-CHOP in non-Hodgkin lymphoma: Results from the CAVALLI phase 1b trial. Blood 2019;133:18:1964-1976 (Amsterdam UMC). 1778. Zhang, Q, Coolen, BF, Nederveen, AJ & Strijkers, GJ . Three-dimensional Diffusion Imaging with SPiral Encoded Navigators from Stimulated Echoes (3D-DISPENSE). Magnetic resonance in medicine 2019;81:2:1052-1065 (Amsterdam UMC). 1779. Zhang, Z, de Munck, JC, Verburg, N, Rozemuller, AJ, Vreuls, W, Cakmak, P, van Huizen, LMG, Idema, S, Aronica, E, de Witt Hamer, PC, Wesseling, P & Groot, ML . Quantitative Third Harmonic Generation Microscopy for Assessment of Glioma in Human Brain Tissue. Advanced Science 2019;6:11: (Amsterdam UMC). 1780. Zhao, L, Lee, VHF, Ng, MK, Yan, H & Bijlsma, MF . Molecular subtyping of cancer: current status and moving toward clinical applications. Briefings in bioinformatics 2019;20:2:572-584 (Amsterdam UMC). 1781. Zhao, L, Wang, W, Xu, L, Yi, T, Zhao, X, Wei, Y, Vermeulen, L, Goel, A, Zhou, S & Wang, X . Integrative network biology analysis identifies miR-508-3p as the determinant for the mesenchymal identity and a strong prognostic biomarker of ovarian cancer. Oncogene 2019;38:13:2305-2319 (Amsterdam UMC). 1782. Zhou, G, Sprengers, D, Mancham, S, Erkens, R, Boor, PPC, van Beek, AA, Doukas, M, Noordam, L, Campos Carrascosa, L, de Ruiter, V, van Leeuwen, RWF, Polak, WG, de Jonge, J, Groot Koerkamp, B, van Rosmalen, B, van Gulik, TM, Verheij, J, IJzermans, JNM, Bruno, MJ & Kwekkeboom, J . Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules. Journal of hepatology 2019;71:4:753-762 (Amsterdam UMC). 1783. Zhuang, M, Vállez García, D, Kramer, GM, Frings, V, Smit, EF, Dierckx, RA, Hoekstra, OS & Boellaard, R . Variability and repeatability of quantitative uptake metrics in 18F-FDG PET/CT of non–small cell lung cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2019 (Amsterdam UMC). 1784. Zondervan, PJ, Buijs, M, de Bruin, DM, van Delden, OM & van Lienden, KP . Available ablation energies to treat cT1 renal cell cancer: emerging technologies. World journal of urology 2019;37:3:445-455 (Amsterdam UMC). 1785. Zou Z, Shen Q, Pang Y, Li X, Chen Y, Wang X, Luo X, Wu Z, Bao Z, Zhang J, Liang J, Kong L, Yan L, Xiong L, Zhu T, Yuan S, Wang M, Cai K, Yao Y, Wu J, Jiang Y, Liu H, Liu J, Zhou Y, Dong Q, Wang W, Zhu K, Li L, Lou Y, Wang H, Li Y, Lin H. The synthesized transporter K16APoE enabled the therapeutic HAYED peptide to cross the blood-brain barrier and remove excess iron and radicals in the brain, thus easing Alzheimer's disease. Drug Deliv Transl Res 2019; 9:394-403 (NKI).