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Annual Report 1968-69

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Annual Report 1968-69 ANNUAL REPORT 1968-69 Chemical Laboratory, Poona NATIONAL CHEMICAL LABORATORY POONA 1968-1969 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH CONTENTS INTRODUCTION SPONSORED PROJECTS PRIVATE PARTIES INTERMEDIATES AND DYES 1. Anthraquinonoid intermediates and dyes I TERPENOIDS 2. Utilization of longifolene and63-carene I 3. Isolation of borneol I 4. Utilization of isolongifolene 2 DRUGS AND PHARMACEUTICALS 5. Carbimazolc 2 6. Mcgimide 2 7. Sorbidc nitrate 3 8. Sulphacetamide and its sodium salt 3 9. 8-Hydroxyquinoline 3 10. Radio-opaque dyes 3 PERFUMERY CHEMICALS II. p-Phenethyl alcohol 4 12. Preparation of perfumery grade geraniol, citronellal and citronellol from Indian lemongrass oil 4 MISCELLANEOUS 13. Analysis of organic compositions of industrial importance 4 I 14. Screening of NCL compounds by Bristol Laboratories, Syracuse, (N. Y.) for pharmaco- logical activity 4 15. Steroids and wax from sugarcane press-mud 5 16. Development of adhesives for decorative laminates 5 17. Technical preparation of liquid stabilizer for PVC 5 18. Technical preparation of pentachlorophenol and other chlorophenolic compounds 5 19. Development of an infra-red spectrophotometer 6 CENTRAL AND STATE GOVERNMENT INSTITUTES 20. Composite drug research scheme on Indian medicinal plants 6 21. Fabrication of Electron Diffraction Camera 7 22. Constitution of lac 7 23. Lac dye 8 24. Titanium tetrachloride from ilmenite 9 25. Pulping of Kashmir soft woods 9 PL-480 SCHEMES 26. Chemical and thermodynamic properties of refractory matcrials at high temperatures 9 27. Work on the synthesis and properties of new type glycol monoalkyl ethers for the control of water evaporation to extend the industrial utilization of cotton seed oil 12 28. Investigation of the effect of heat on tung oil and derivatives of tung oil and the chara­ cterization and identification of compounds rcsulting from heat treatment to extend the utilization of tung oil 13 II 29. Wood phenolics with special reference to their use in chemolaxonomy and their biosynthesis by tissue culture studies 14 PILOT PLANTS 1. Aniline 17 2. Industrially useful products from polysaccharides 17 3. Phthalates 18 4. Technical preparations of organic intermediates 18 5. Fine Chemicals Project 19 PRODUCT ORIENTED RESEARCH 1. Cadmium sulphide photoconductive cells 20 2. Tin oxide resistor 20 3. Ferroelectric materials 21 4. Posistors 21 5. Polycrystalline silicon 22 6. Ferrite compositions 22 7. Potential Catalyst materials 23 7*1 Alumina 23 7*2 Molecular sieves 23 8. Silicones and silicone intermediates 24 9. Ethyl silicate 25 10. Burning of TiCI4 in oxygen to produce rutile titania 25 11. Polytetraf luoro ethylene 26 ni 12. Butyl titanate 26 13. Utilization of some mineral concentrates 27 14. Preparation of magnesium and magnesium calcium silicate for thermal insulation 28 15. Chromatographic adsorbents and other chemicals 28 16. Aluminium silicate as rubber filler 29 17. Aluminium hydroxide gel 29 18. Di-o-tolylbiguanide 29 19. Dyes for synthetic fibres 29 20. Technical preparations of organophosphorous compounds 30 20-1 Triethyl phosphate 30 20-2 Tris-nonylphenyl phosphite 30 20-3 Trioctyl phosphate 30 20-4 Triphcnyl phosphate 31 21. Simazine 31 22. Hydroxyethylstarch 31 23. Saccharification of cellulose 31 24. Cellulose powder 32 25. Synthetic glycosides and other synthetic carbohydrate materials 32 25-1 Glycosides and thioglycosides 32 25 * 2 Phenolphthalein-D-glucuronide 32 IV 26. N-acetylneuraminic acid 33 27. Substitute for gum arabic 33 28. Cashewnut shell gum 34 29. Vitamin B0 34 30. N, N-diethyl-raeta-toluamide 34 31. Colchicine 34 32. Terpin hydrate and terpineol 35 33. Allantoin 35 34. para-Nitrophenol 35 35. para-Acetylsulphanyl chloride 36 36. 19-Norsteroids and other modified steroids 36 37. Preparation of photosensitive chemicals 36 37-1 2:3-Dihydroxynaphthalene-6-sulphonic acid 36 37-2 Light sensitive stabilized diazonium salts 36 38. Theophylline — caffeine 37 39. para-tert-Butylcatechol 37 40. Catechol 37 41. 2-Aminopyrimidine and sulphadiazine 38 42. Purification of anthracene 38 43. Acetylacetone 39 44. Stationary liquid phases and solid support for GLC instruments 39 45. Conversion of dehydrocostus lactone into chamazulene and s-guaiazulene 39 46. Phenobarbitone 40 47. Salicylaldehyde 40 48. Stabilized gel for hot and cold sachets 40 49. Acrylic base cation exchange resin 41 50. Polystyrene foams 41 51. Sulphochlorinated polyethylene 41 52. Nitrile rubber 42 53. Rubberized cork sheets 42 54. Polysulphide rubber 43 55. Utilization of coir pith 43 56. Latex foam backed coir 43 57. Rubber reclaiming agents 43 58. Rubber blowing agents 44 59. Styrenated alkyds 44 60. Linseed oil emulsions 44 61. Coating for nylon fabric 45 62. Leather coatings 45 63. Resins for automobile filters 45 64. Isocyanate-based coatings 45 65. Diamond setting cement 46 VI 66. Rubber base adhesives * • 46 67. Materials for artificial limbs • • 46 68. Composite propellents 46 69. Sealants for canvas bags . 47 70. Synthetic polymers for oil well drillings • • 47 71. Synthetic polymer for cane juice clarification 47 72. Utilization of a bye-product available in the manufacture of terephthalic acid • • 48 73. Micro filters • * 48 74. Xylene formaldehyde resins 48 75. Foundry chemicals 48 75* 1 Shell moulding resin 48 75-2 Sinol core binder 49 75-3 Dry core binder 49 75*4 Starch phosphate 49 75-5 Double boiled linseed oil substitute . 49 76. Low temperature fluxes 50 77. Substitute for dextrin • • 50 78. ChlorobeHzenes * * 50 79. Ethylenediamine • • 51 80. Chlorination of methane gas 51 81. Ethyl acetoacetate • * 52 VII 82. Preparation of sorbitol and mannitol from invert sugar • • 83. Phenacetin • • 84. Analytical vapour phase chromatograph • • 85. Preparative vapour phase chromatograph • • 86. ESR spectrometer • • 87. Self balancing strip-chart recorder • • 88. Fabrication of a precision ultrasonic interferometer • * 89. Equipment for the determination of total solid content in latex compositions, cements and adhesives • • RESEARCH PROJECTS 1. Theoretical investigations in solid state • • I • 1 The ligand field theory of trigonal bipyramidal complexes • • 2. Materials for solid state devices • - 2-1 Ferroelectric materials • * 2*2 Chalcogenide spinel semiconductors * * 2-3 Metal-insulator-metal sandwiches • * 2-4 Photoconducting materials • • 2-5 Magnetic properties of decomposition products of iron oxalates • • 3. Nuclear and radiation chemistry * • vni 3-1 Studies on MOssbauer effect 59 3*2 Hydroxylation of aromatic hydrocarbons by radiolysis 60 3 • 3 Diffusion of rare earth metals in copper 60 4. Thermodynamic studies 62 4 • 1 Thermodynamic properties of solutions 62 4-2 Thermodynamics of metal ion complex formation in solutions 62 5. Thin films 63 5-1 Structure of thin films 63 5 • 2 Physics of thin films 64 6. Crystal and molecular studies 65 6 • 1 Crystallography 65 6-2 Spectrochemical studies 65 7. Synthetic inorganic chemistry 66 66 7 • 1 Titanium and tin organics 66 7*2 Coordination compounds 7-3 Fluorine chemistry 68 8. Physico analytical chemistry 68 8-1 New reaction of analytical importance 68 9. Natural organic products 70 9 * 1 Utilization of p-himachalene 70 9 • 2 Celastrus paniculatus 70 IX 9 • 3 Utilization of bye-products of opium alkaloid industry 70 9*4 Oleorcsins and resinoids 71 9 • 5 Chemical investigation of Shoma arabica 71 9 • 6 Mucopolysaccharides 71 9-7 Codextrmization of some indigenous gums and other polysaccharides 72 9-8 Chemical examination of Vetivaria zizanoides 72 9*9 Synthetic experiments on berberine alkaloids 73 9* 10 Structure of salvin and picrosalvin 73 9-11 Nimbinin and related products 73 9*12 Conformational studies 74 10. Synthetic organic chemistry 74 10 • 1 4-Acetomethylcoumarines 74 10*2 Synthetic studies in 4-arylcinnolincs and 2-arylquinoxalines 74 10-3 Transformation products of carvonc and limonenc 75 10-4 Transformation products of costunolide * • 76 10-5 Synthesis of compounds related to selinane, 77 elemane and p-menthane • .• 77 10-6 Chemical transformations of dehydrocostus lactone 78 10-7 Synthesis of sarkomycin • • 78 10-8 Transformation products of eudesmol * • 78 10-9 Flavonoids • • x 10* 10 Naturally occurring anthraquinone pigments * • 79 10-11 NMR spectra of anthrones . 79 10* 12 Zinc dust distillation of hydroxyanthraquinoncs carrying methyl groups - * 79 10-13 Tetrahydroxyanthraquinones • • 80 10*14 Synthesis of colucidin • • 80 10-15 Studies in synthetic dyes • - 80 10-16 Studies in heterocyclic compounds • * 82 10-17 Antifertility drugs 85 11. Physical organic chemistry • • 87 11-1 Mass spectrometry • - 87 11-2 Studies on conjugated systems • • 88 12. Microbiology 91 12-1 National Collection of Industrial Microorganisms 91 12-2 Production of mutants 92 12-3 Microbiolog cal transformation of terpenes 92 13. Growth of plant cells 93 14. Enzymes • * 94 14-1 Hexokinase 94 14-2 Phytase * • 94 14-3 DPNase 95 14-4 Acetylcholinesterase 95 14-5 Acylphosphatase • • 96 XI 14-6 Metabolism of nitrate by Achromobacter fischeri 96 14-7 Citrate-oxaloacetate lyase (Citrase) 97 14-8 DFP-Susceptible enzymes and antidotes 97 14-9 Enzymes and the metabolism of organic acids 98 15. Physico chemical studies on polymers 98 15-1 Stereo specific polymerization 98 15*2 Degradation of long chain molecules by ultrasonics 99 16. Chemical engineering studies 99 16-1 Design cell 99 16*2 Fluidization 99 16-3 Mass transfer 100 16-4 Diffusion in solid catalyst 100 16-5 Reaction models and reactor design 101 16-6 Distillation 101 16-7 Development of a continuous process for the preparation
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