SPECIAL GRADUATION ISSUE COMING MAY 17
SEPTEMBERMAY 31, 2019 20, 2019 MEDICAL UNIVERSITY OF SOUTH CAROLINA VOL.VOL. 36,36, NO.NO. 2012 relate to 625,000 square feet. When you walk around it, it’s massive. It’s a full city block. It’s spectacular.” The kids at the event were more focused on fun than hospital tours. There was face painting, arm painting, a “dunk a doctor” tank, a place for kids to try bike riding, a kissing booth featuring pet therapy dogs, bubbles, jugglers, people on stilts and more. “Yea, I did it,” said 3–year–old Adeline Pack after a dunk tank ball toss that hit the target, plunging a medical resident into the water. But the employee-led tours were the draw for a lot of adults. “We’re so excited to have you all come in and look around,” said Katy Decker, RN, nurse manager of the mother–baby unit, to a group of about a dozen women and men. Some of the women were visibly pregnant. “We’ll go through the nursery area where your baby might be but hopefully your baby will stay with you,” Decker said as they walked through a hall and arrived at a labor and delivery room. “There’s an iPad outside every room that will automatically flow from our electronic medical Photos by Sarah Pack records. It will show your name, if you have any dietary A young visitor gets a design on the arm just outside the MUSC Shawn Jenkins Children’s restrictions, any kind of allergy or isolation you have to Hospital and Pearl Tourville Women’s Pavilion. be on; it will all be here.” Inside each room, a large screen shows the patient which doctors and nurses are coming in, reading their information off employees’ badges and displaying it to Families get chance to ‘peek and make their names and roles easier to keep track of. play’ at new high-tech hospital See Play on page 2
By Helen AdAms billed as a chance to “peek and play.” The hospital is scheduled to open in October. [email protected] Shawn Jenkins himself was on hand, quietly talking aith Smith is due to have a baby in late December, with people and watching as tour group after tour group Fand after touring the labor and delivery unit in the headed in to check out the hospital. “It’s just the joy of brand–new hospital where she’ll give birth, she’s ready. a lifetime to see this building and meet all the people “My twin sister just had a baby in July, on the 29th, and we’ve been able to meet. Today, watching expectant I get to brag to her how much better mine is going to moms and dads and kids coming through — it’s been be. It was really pretty.” fantastic.” Smith was among about 400 people who visited the He said the hospital, which stands near the MUSC Shawn Jenkins Children’s Hospital and Pearl intersection of Calhoun Street and Courtenay Drive Tourville Women’s Pavilion on Sept. 14 for an event in Charleston, is bigger than he imagined. “It’s hard to Mom-to-be Faith Smith has fun with bubbles.
Patient Gift School–based clinic 4 Gotcha Bikes arrive It’sMICU flu staff shot honored time for BelovedFirst–of–its–kind faculty clinic member opens in 5 Meet Bea Heaman 5 Meet Alexis Nagel exceptional care. leavesNorth Charleston. legacy 6 Bahamas Relief Don’t be caught 8 MUSC Research Day 2 unprotected. 3 Pioneer touched many lives. 9 Innovator awards 2 mUsC CAtAlyst news, September 20, 2019 Roll up your sleeve — it’s time for flu shots Flu already circulating around the Palmetto state By leslie CAntU even if you’ve been vaccinated, you’ll [email protected] likely come down with a much milder case, Mack said. It’s that time of year again — pumpkin And, she stressed, the flu shot will not spice is everywhere, the temperature is give you the flu. almost bearable and flu season is right “That’s not possible,” she said. around the corner. The flu shot uses an inactivated virus In fact, says Elizabeth Mack, M.D. — in other words, the virus is dead. The “the flu is already circulating in South nasal spray does use a live virus, but Carolina.” it’s been weakened. Theoretically, it’s Mack is chief of the Division of possible to get the flu from the nasal Pediatric Critical Care at MUSC spray, so for that reason, the spray isn’t Children’s Health as well as a recommended for pregnant women, spokeswoman for the American Academy children under 2 years old, adults over Photo by Heather Hazzan, SELF Magazine of Pediatrics. 49 years old or people with weakened The CDC reports that 134 children died because of influenza in the She said that it’s important for immune systems. 2018-19 flu season. Doctors recommend that everyone older than 6 months everyone 6 months of age and older Young children who’ve never gotten get the flu shot. to get the flu shot, and that includes a flu shot or who have only ever had children, adults, pregnant women and one shot need to get two doses to build breastfeeding mothers. It’s particularly up their immunity, according to AAP Continued from Page One designed to accommodate the Coast important for people who are around PlAy recommendations. Guard’s new Jayhawk helicopter for babies under 6 months old, because The flu vaccine is “incredibly safe,” The hospital also features: emergency and disaster situations. infants that young can’t get the shot, and Mack said, adding that it makes so much q Twenty percent more patient beds q Access to kitchens, laundry people who have immunocompromised more sense to get the vaccine than to roll than the current hospital. facilities and showers for families family members. the dice and think, “Oh, I’ll just take q An advanced fetal care unit and the staying at the hospital for an extended “The flu can be deadly,” she said. Tamiflu if I get sick.” largest neonatal intensive care unit in time. The Centers for Disease Control and Antivirals, including Tamiflu, are not the state. q Multiple play spaces for kids. Prevention reported 134 confirmed cases substitutes for being vaccinated, Mack q Floors dedicated to children with Smith, hoping to have her baby of children dying of influenza during the said. Antivirals have side effects, they’re cancer and heart problems. before the end of the year, said she 2018–2019 flu season. expensive and they’re often in short q A rooftop helicopter landing pad loved it all. “I can’t wait." This year’s shot protects against four supply. strains of the flu and includes two strains To ensure that immunization lasts that weren’t in last year’s formulation, through the worst of the flu season, Mack said. it’s best to be vaccinated by the end of Although it is possible to get the flu October, Mack said.
Editorial Office The MUSC Catalyst News is MUSC Office of PublicAffairs & published bi-monthly. Paid Media Relations, 135 Cannon advertisements,which do not Street, Suite 403C, Charleston, SC represent an endorsement by MUSC 29425. or the state of South Carolina, are 843-792-4107 handled by Island Publications Inc., Fax: 843-792-6723 Moultrie News, 134 Columbus St., Charleston, S.C., 843-958-7480, 958-7384, Editor: Cindy Abole 958-7488 or 937-7489. E-mail: advertising@ [email protected] moultrienews.com. 3 mUsC CAtAlyst news, September 20, 2019 A caring mentor: A life well lived Endocrinologist made contributions in 57-year career Nuclear Medicine laboratory until 1983. By Cindy ABole In 1960, the Buses had the distinction [email protected] of being awarded the first National nvestigator, educator, physician, Institutes of Health (NIH) grant in South Imentor and friend. These words best Carolina for their scientific project, describe the life and career of longtime “Factors that Modify Insulin.” After MUSC clinical scientist Maria Gordon her husband’s death in 2001, Dr. Buse Buse, M.D. Dr. Buse died peacefully at maintained the NIH RO–1 grant for her home surrounded by her family on a total of 54 years — considered to be Aug. 25. She was 92 years old. among the longest continuous grants Dr. Buse long kept a childhood pledge awarded by the NIH — for 10 competitive that she made as a 16–year old World renewals (1960 to 2014). War II survivor interned in a Russian Dr. Buse was a member of several labor camp in wartime Europe. She professional organizations, including the committed to support an intolerance Endocrine Society, American Diabetes of fascism and prejudice in an effort Association, the American Society to appreciate life through knowledge, of Nuclear Medicine and American beauty and nature. She embraced this Federation of Clinical Research. She Photo Courtesy of MUSC Waring Historical Library concept throughout her life and a wrote and co–authored numerous Dr. Maria G. Buse in her lab. career of 50–plus years as a dedicated publications throughout her career and a distinguished career, a devoted spouse M.D./Ph.D. student in her lab, Maria scientist and practicing endocrinologist. received many honors and awards that and beloved family. It wasn’t easy, but it provided me with training in cutting- Through her work, Dr. Buse would include the 2003 American Diabetes surely was great. Put simply, Dr. Buse was edge science. I learned how to design make substantial contributions toward Association’s Albert Renold Award, an inspiration to us all – students, faculty experiments, critically evaluate data and the understanding and treatment of South Carolina Governor’s Award and staff. It was a privilege to work with how to read the literature… all those diabetes, insulin resistance, insulin for Excellence in Science and MUSC her. She is greatly missed.” things that a mentor should do. More receptor regulation and various topics Distinguished University Professor. Cardiology professor and Gazes importantly, Maria became my role related to endocrinology. MUSC President David J. Cole, M.D., Cardiac Research Institute director model, my ‘mom’ and a lifelong friend. Her research led to notable FACS, praised Dr. Buse for leaving such Donald R. Menick, Ph.D., remembers She was one of the most adventurous contributions with respect to the a notable legacy. “Maria Buse was a Dr. Buse’s collaborative spirit and people that I’ve known and a fearless understanding of diabetes mellitus. Dr. leader in academic medicine, and her professionalism. “Maria was an traveler,” he said. Buse devoted her career to discovery and legacy for medicine and research funding inspiration to me and to so many of Burant was able to travel with research. is remarkable. MUSC was fortunate to us at MUSC. When I arrived in the Dr. Buse, first as a student, and in Dr. Buse was born July 17, 1927 in be graced by her presence and service for late 1980s, we started a collaboration, subsequent years as they attended Budapest, Hungary. She attended the so many years.” which quickly turned into a wonderful scientific meetings together and shared Pazmany Peter Catholic University Jerry Reves, M.D., dean emeritus of mentoring experience for this newly in world cultural experiences. School of Medicine in Budapest and the College of Medicine (2001-2009), minted assistant professor. I learned so “But the memories that I treasure University of Basel in Basel, Switzerland, has fond memories of Dr. Buse, going much from her. I loved sitting down more than any other are the many nights from 1945 to 1948 and completed her back to his days as a medical student at with her over breakfast in the cafeteria that Mary and I, Marie and John would medical school education in 1952 at the MUSC from 1965 to 1969. “At the time, or for coffee later in the day and talking spend together at their home on Bennett University of Buenos Aires. Her research there were very few women in medicine science. She was an outstanding scientist Street grilling steaks, drinking wine and career began shortly afterward as she — in our class of 75 medical students, and dear friend. Her enthusiasm for talking about science, politics, culture worked under physiology Nobel laureate just two were women — so by gender biomedical research touched the lives of and MUSC gossip until late at night. I Bernardo Houssay and his team in 1956. alone, Dr. Maria Buse stood out to young so many faculty and trainees at MUSC. still have the simple wine pull that Maria In 1957, she met and married John medical students,” he said. “But she was She is held in the greatest esteem by so and John gave me when I graduated. It Buse, M.D. Later that year, the Buses much more than a rare female physician. many and is sorely missed.” sits mounted by my desk. At this time, joined MUSC as faculty members in the She stood as an academician of the Among those touched by her Mary and I will grill a steak, use the wine College of Medicine. highest order. Then I was dean of the mentorship were her colleagues and pull and toast a very special woman.” They published their first research College of Medicine in 2001, Dr. Buse students. Medical Scientist Training Her husband, John F. Buse, M.D., article together on action sulfonylureas was a role model that I often referred Program graduate Charles Burant, M.D., precedes Dr. Buse in death. Her three in animal models (Diabetes, 1957). our students to — today’s medical school Ph.D., and his wife, Mary Treutelaar, got children, John B. Buse, M.D., (Mary She helped co–found the Department class is about 50 percent women — as an to know Dr. Buse in and out of the lab. Beth Cassely) of Chapel Hill, North of Endocrinology with her husband aspiring female academic physician and “Maria Buse was truly one of the Carolina; Paul Edward Buse, M.D., and was co–director of the Division of an example of how ‘you can have it all’ — most important people in my life. As an See Pioneer on page 11 4 mUsC CAtAlyst news, September 20, 2019
“It’s far and away the best surgical treatment we have for sleep apnea. CPAP remains the gold standard, and we all recognize that. But for people who can’t — and there is a large population who can’t tolerate CPAP — those patients can be very well served by the use of this device,” Lentsch said. Long was one of them. Although the CPAP did help, it was also kind of an annoyance. The hoses have to be cleaned — either manually or with an expensive after–market system; there’s no such thing as an impromptu Saturday afternoon nap on the couch; and you have to lug the machine with you when you travel. “I went on a cruise with it one time, and it was awful. Awful!” Long said. And most importantly, the user might subconsciously remove the breathing mask in the middle of the night and not reap Photos by Sarah Pack the machine’s benefits. Long estimated he Chris Long, R.N. says his sleep apenea used to leave him dragging at work. Now he gets a full night’s rest and is would wear it for only four or five hours ready for his shift prepping patients for surgery. each night before taking it off in a sleepy daze. The Inspire device, on the other hand, is permanently implanted in the user. New surgery promises full night of During surgery, the doctor makes three 1–inch incisions — one below the jawline, another below the collarbone and the rest for sleep apnea sufferers final between the ribs. The surgeon places By leslie CAntU doctor in Charleston who implants the the risk of a heart attack, stroke, certain a stimulation lead around the hypoglossal [email protected] Inspire sleep therapy device. cancers and diabetes. nerve, which controls tongue movements, then implants the generator below the A simple outpatient surgery is making “It’s essentially a pacemaker for patients MUSC was one of the study sites for collarbone and finally, places a sensing a huge difference for one MUSC Health with sleep apnea in an effort to open their the Inspire device trial. The initial one- lead between the ribs. nurse’s quality of life. airway during sleep,” Lentsch said. year results showed a 78% reduction in The sensing lead senses when the user Chris Long, R.N., didn’t realize he had Sleep apnea is a sleep disorder in which sleep apnea events per hour, according is about to take a breath and signals sleep apnea until he switched to the day a person’s upper airway becomes blocked, to Inspire Medical Systems, a medical the stimulation lead to stimulate the shift five years ago. But after starting each reducing or stopping airflow. It interrupts technology company that spun out of hypoglossal nerve, which moves the shift at 5:15 a.m., he found himself ready the person’s sleep, but it can also increase medical device leader Medtronic. tongue forward, forcing open the airway for a nap by 9. Visits with various doctors and allowing the user to breathe properly. and a sleep study revealed he had sleep The Inspire “This happens within a split second,” apnea, and he began using a continuous device is based Lentsch notes. positive airway on pacemaker The patient can go home the same pressure machine, technology. day. Thirty days after surgery, once the better known as patient has fully healed, the device is a CPAP, to help activated, and the patient can begin using him breathe at it at night. Just before bed, the patient night. turns the device on with a remote control. After years of Inspire begins its work after a preset being tethered interval of time to allow the user to fall to the CPAP asleep — in Long’s case, that’s 20 minutes. each night, Long His girlfriend has told him that now, his was ready for a snoring stops as soon he hits that 20– change. Luckily, minute mark. He’s even recorded himself he was already Lentsch and heard his snoring cut off mid–snore under the care of ear, nose and throat doctor Eric Lentsch, M.D., the only See Sleep on page 10 5 mUsC CAtAlyst news, September 20, 2019
Meet Bea
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IP04-1817952-1 6 mUsC CAtAlyst news, September 20, 2019 ‘There was a town, but it was all gone.’ MUSC photographer helps deliver supplies to devastated Bahamas in aftermath of Dorian
By Helen AdAms and an Army veteran, was there to help deliver 10,000 pairs of shoes from [email protected] the Charleston-based fishing apparel rennan Wesley’s first impression company Huk and capture it all on film Bof the Bahamian town of Marsh and video. Harbour was bleak. “They need shoes desperately because “There’s nothing there,” he people are getting tetanus because of all remembers of his view from a plane the debris on the ground,” he says. carrying relief supplies last week in the A friend asked Wesley to join the aftermath of Hurricane Dorian. Sept. 9 mission, and the photographer Photo by Brennan Wesley “I could see out of the window. There didn’t hesitate once he got the OK to The Bahamas’ beautiful blue water remains, but not much else in this was a town, but it was all gone. It was take off from work at MUSC. Saying view of Marsh Harbour. just boards. There was an airport tower, "yes" to people in need is part of Wesley’s your first nature — Yes, go.” destroyed most of the homes. but the structure next to it was gone. professional and personal code. Hurricane Dorian struck the Bahamas Wesley’s journey there began in a The hangars were gone. There was a “We work in a hospital. That’s what we on Sept. 1 and didn’t leave for two days, Charleston warehouse, where he helped runway and pine trees that were just do. We don’t work in a bank or whatever causing at least 50 deaths. In Marsh load the shoes onto two trucks. One snapped in half.” other profession. You’re around people Harbour, a town of about 6,000 in went to Stuart, Florida, and the other Wesley, a photographer with MUSC who do this all the time. This should be the Abaco Islands, Bahamas, Dorian See Bahamas on page 7
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Left photo: Ten-thousand pairs of Huk shoes are loaded to ship to the Bahamas. Right photo: Hurricane relief supplies fill a cargo plane headed to the Bahamas, including shoes from a Charleston-based company.
Photos by Brennan Continued from Page Six we flew in.” BAHAmAs Wesley says the plane was packed. He Wesley sat wedged in the back while the pilot got to West Palm Beach. Both are departure ready for takeoff. “He was on the runway points for Dorian relief supplies headed going, ‘This is the heaviest this plane was. endured. to the Bahamas. Wesley’s truck went to has ever been. I’ve never taken off with Then his team got back on the plane. “All the anxiety you feel going through the airport in West Palm Beach. this much weight in this plane.’ And I’m The pilot had deadlines to meet. a hurricane. Imagine if everything got “We left Charleston at 4:30 that like…” Wesley trails off with a smile. As a native Floridian who lived wiped out and you stayed, where would afternoon and got to West Palm at 2:30 The plane took off safely, but the through Hurricane Andrew, and now you go to get water? Where would you in the morning. We stayed at a hotel pilot’s challenges didn’t end there. “It’s a resident of Charleston, which sees go for help? You feel bad for people. It’s from 2:30 to 6. Then we got up, went a 45–minute flight from West Palm to its share of storms, Wesley tries to horrible. But people will rebuild. You to the airport, unloaded everything, Marsh Harbour,” Wesley says. “And imagine what the people of the Bahamas can’t stop these things.” and from 7 to about 8:30, we shrink– there’s people who aren’t on radar so you wrapped pallets of shoes.” Each pallet have to keep your eyes out. All over the would go to a different area in the place. From the U.S. to the Bahamas, Bahamas based on need. you have to file a flight plan but people They weren’t alone — other people flying from island to island are just doing were delivering supplies there, too. whatever. There are airplanes all over the “Shoes, tools and ice. A certain amount place.” of each product goes on each of these When they finally got to Marsh shipments. We were going to Marsh Harbour, Wesley and another passenger Harbour. They evacuated the whole jumped off to unload their cargo. It island except for a few stragglers. So we joined a pile of donated goods. “There needed shoes for the people coming in was a cinder block building, I guess to do relief work if they were local. They where there used to be Customs. Most of also needed tools and tarps. Biggest the stuff was stacked next to that.” thing they needed was ice. We had three There were also body bags, Wesley says 300–pound coolers of ice on the plane — a reminder of how devastating Dorian
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By BrAndon yoUng into this group of eminent scientists, many of whom have been mentors [email protected] and researchers that I have admired Patrick M. Woster, Ph.D., SmartState throughout the years,” Woster said. Chair in Drug Discovery and chair of Induction into the Medicinal the Department of Drug Discovery Chemistry Hall of Fame requires and Biomedical Sciences at the MUSC nomination by two ACS division College of Pharmacy, was inducted into members and selection by the Executive the Medicinal Chemistry Hall of Fame Committee. Receipt of this award on Aug. 27 at the National Meeting of validates a successful career for Woster, the American Chemical Society (ACS) in who came to MUSC in 2011, after stops San Diego, California. Woster was one at Wayne State University, University of of only four researchers worldwide to be Michigan, and University of Nebraska inducted this year. He joins fewer than Medical Center, where he attained 100 elite scientists, three of them Nobel his doctoral degree. Throughout his laureates, who were previously honored academic career, Woster has been with Hall of Fame membership for their committed to the field of chemistry, significant contributions to the field of evidenced by his 25 years of service on Photo by Sarah Pack Medicinal Chemistry and the training of the executive committee of the ACS Dr. Patrick Woster in his lab. future medicinal chemists. Division of Medicinal Chemistry. The field of Medicinal Chemistry The work of medicinal chemists is chemical structure to maximize great science can’t be done in isolation. uses a combination of chemistry and crucial to the development of new drugs, potency and efficacy, but also to make His own work has benefited from a 30– biology techniques to discover new according to Woster. compounds orally active and to ensure year collaboration with Robert Casero, pharmaceuticals for the betterment of “Medicinal chemists are the first they can reach their target in a human Ph.D. at Johns Hopkins University. They human health. step in the drug discovery pipeline,” patient.” were the first to produce small–molecule “It is a great honor to be inducted explained Woster. “They optimize Woster is the first to acknowledge that See Award on page 10 David Kent and CharlotteLemon ExperienceMatters
David Kent 24 years CharlotteLemon 21 years 843.606.0824 843.900.1322 [email protected] [email protected] www.DavidKent.Net www.CharlotteLemon.Net IP02-1817121-1 Representing BuyersExclusively forover45years 9 mUsC CAtAlyst news, September 20, 2019 Third quarter MUSC innovator awards celebrate employees Individuals, teams inspire innovative ideas, solutions Staff Report ponsored by the Office of Innovation, the “I am an SMUSC Innovator” campaign is designed to raise awareness of the many forms that innovation can take, to inspire others and to publicly recognize individuals/ teams that are making an impact. For additional information, contact Jesse Goodwin, Chief Innovation Officer ([email protected]).
B. DaNine Fleming, Ed.D., faculty director of training and intercultural education in the Department of Diversity, Equity and Inclusion. Problem — Creating a comprehensive learning and training curriculum that can meet our diverse enterprise on an individual level is one way that I continue to turn what some may define as pain into pleasure. I am keenly aware of the intent and the impact of this work, so I make a concerted effort to adjust and modify the curriculum, so it can represent the strategic goals and Photo by Anne Thompson objectives of our evolving enterprise. It is my pleasure to Third quarter MUSC innovators are Dr. Jeff Borckardt, from left, Dr. Sherine Chan, Dr. Brandon serve the MUSC enterprise. Welch, Ellen Debenham and Dr. James Chou. Not pictured: Dr. DaNine Fleming. Impact — Creating the team skills/appreciating diversity and the National Institutes of Health. Grants from the history to assess hereditary cancer risk, the need for and inclusion experience for first year students, working South Carolina Research Authority, South Carolina collecting clinical or research data directly from patients on innovative ways to relay some difficult concepts Clinical & Translational Research Institute and the and, finally, the need for patients to receive reminders that include, but are not limited to: identifying MUSC Foundation for Research Development. of things to do between appointments. and addressing unconscious bias, recognizing Impact — I developed Doxy.me, a telemedicine microaggressions in the classroom/workplace, and solution used by over 60,000 health care professionals refining skills to effectively deal with difficult people, Jeff Borckardt, Ph.D., assistant provost, to conduct over 5,000 telemedicine sessions per day. I Recognition — Willette Burnham–Williams, Ph.D.; Interprofessional Initiatives and director of the developed ItRunsInMyFamily.com as an effective way Paula Sutton; Ronnie Chatterjee; Tamatha Psenka, Division of BioBehavioral Medicine. to collect family cancer history and identify patients at M.D.; Lisa Montgomery; and David Cole, M.D., FACS. Problem — After developing the Sloppy Mountain risk for hereditary cancer. We launched Dokbot, a new Medical Center activity, there was a challenge in chatbot platform focused on collecting patient–reported effectively marketing it and driving adoption. health data for clinical care or research. Finally, I am Sherine Chan, Ph.D., and C. James Chou, Ph.D., Impact — We spawned the launch of a start–up developing Adhere.ly to help mental health providers associate professors, Department of Drug Discovery and company (Palmetto Innovative Education, LLC) remind their patients to complete their assignments Biomedical Sciences. that licenses the software from MUSC for sale and between session activities. Problem — Routinely finding that many drugs on distribution to other institutions around the country. Recognition — Dylan Turner; Heath Morrison; Joshua the market for neurological disease don’t work for The software has already been implemented in large– Schiffman, M.D.; Caitlyn Allen; Jordon Ritchie; Brian many patients, in part because these drugs target the scale team–building events at over six academic medical Bunnell, Ph.D.; Doxy.me team; ItRunsInMyFamily symptoms rather than the underlying causes. institutions, professional organizations, and universities. team; Dokbot team; and Adhere.ly team. Impact — We have discovered a new class of Recognition — Dusti Annan–Coultas, Ed.D., and Mary mitochondrial modulator compounds based on Mauldin, Ed.D. Vitamin K that improve mitochondrial health in Ellen Debenham – R.N., director of Business multiple animal models of difficult to treat neurological Development, MUSC Center for Telehealth. diseases such as medication–resistant epilepsy, Problem — Prior to the development of the South Brandon M. Welch, Ph.D., assistant professor, Center Parkinson’s disease and mitochondrial DNA depletion Carolina telestroke networks, less than 40% of the for Biomedical Informatics, Department of Public syndrome. state’s population lived within a 60–minute drive time Health Informatics. Recognition — Small Business Technology Transfer and from expert stroke care. Now, greater than 96% of Problem — The industry was lacking several solutions Small Business Innovation Research grants from the the state’s population has access to this time–sensitive for patient needs, including the ability for them to meet National Institute of Neurological Disorders and Stroke treatment. providers by video, the need for gathering family health See Innovators on page 12 10 mUsC CAtAlyst news, September 20, 2019
Continued from Page Four Continued from Page Eight sleeP determine the pattern of how the airway AwArd collapses — the Inspire device works for a “His tremendous success when the device turns on. specific type of collapse, so patients must inhibitors of lysine–specific demethylase as a research scientist Lentsch said Inspire works very well undergo a drug–induced sleep endoscopy 1 and to show that they help to re– for most users. “We’ve had very high to determine their suitability for the express tumor suppression factors. illustrates the pairing of success rates, maybe even surpassing the surgery, O’Bryan said. “I’ve enjoyed the collaborative nature hard work with a profound company’s.” The final step is getting insurance of this type of work and science cannot Part of the reason for the high success approval, which is getting easier. be done alone,” said Woster. “You must and curious mind, which rate is the screening that happens “We’ve had a dramatic change in have great collaborators like Bob to be is an inspiration for the before surgery. Nurse practitioner insurance coverage in the last six successful.” Claire O’Bryan, part of the ENT months,” O’Bryan said. Woster has also been an inspirational students he teaches and team that handles Inspire surgeries, Long was watching the insurance mentor for the next generation of faculty he mentors.” does an extensive workup of patients situation closely. Eager for the surgery, medicinal chemists. to determine if they would be good he called everyone he could think of to “I’ve really enjoyed working with candidates for the surgery. encourage insurers to cover it — from graduate students, seeing them mature Phillip D. Hall, Pharm.D. First, she said, the patient should have human resources at MUSC to U.S. Sen. as scientists, watching them go out and moderate to severe apnea. Second, the Lindsey Graham. In March, Blue Cross succeed,” said Woster. “They are kind of mind, which is an inspiration for the patient should have a body mass index Blue Shield of South Carolina began like your kids in a way, and it’s extremely students he teaches and the faculty he of 35 or lower. Then, she talks to the covering the surgery, and on May 6, gratifying to see them do well.” mentors. His wit and warmth brighten patient about why he or she wants the Lentsch implanted the Inspire device in Woster’s commitment to science and the lab and the classroom, and we are surgery. Long. training are also held in high esteem at blessed to have him as a leader. We’re “We don’t want to implant anybody Long is glad he had the surgery. He MUSC. very gratified he is getting this richly that is there just because they don’t recommends it to anyone struggling with “Pat is an outstanding role model in deserved recognition.” like their CPAP. We don’t want to sleep apnea. the College of Pharmacy,” said Phillip D. Induction into the ACS Medicinal implant people that have unrealistic “It’s a totally different ballgame. I feel Hall, Pharm.D., dean of the College of Chemistry Hall of Fame acknowledges expectations,” she said. great during the day,” Long said. “I get a Pharmacy. “His tremendous success as a on a national stage Woster's outstanding Next, the surgical team looks at the full night’s sleep, and I feel rested when I research scientist illustrates the pairing of career not only as a scientist but as a patient’s throat anatomy in action to wake up.” hard work with a profound and curious colleague, collaborator and mentor. AtThetent Rightion ALLPeDeople.partment Right NoHewads HELPINGHELPINGHELPING To Do List: Order Employees for administrative support MUSCWITHMUSCWITHMUSCWITH THEIR THEIR THEIR accounting non-clinical professionals trades STSTSTAFFINGAFFINGAFFING support services SOLUTIONSSOLUTIONSSOLUTIONS communications Call: Vicki Hotchkiss (843)224-5796 15055 RReeemmountoou Rd IP04-1819538-1 Looking for work? Email your resume to [email protected] North Charleston, SC 29406 11 mUsC CAtAlyst news, September 20, 2019
Pioneer Continued from Page Three In lieu of flowers, memorials may be made to the Maria G. Buse, M.D. Endowed Chair in Medical Research, a fund established as a tribute to Dr. Buse in 2010. Send (Susan Buse) of St. Louis, Missouri; and Elizabeth Buse King (Charles King) of contributions to the MUSC Foundation, 18 Bee Street, MSC 450, Charleston, Atlanta, Georgia; and other family survive her. South Carolina, 29425.
Reflections on the life and was an important part of my personal her to distinguish her from Dr. John Buse, her lifelong partner) in the Endocrine impact of Dr. Buse and professional life, and she gave me Division for over 25 years). Of the very few people that indelibly impacted my courage in navigating the challenging career from the time I was a fellow and as faculty, she was at top of the list. Dr. Buse was a great woman in many fields as a female academic. I miss her. Although I didn’t work directly under her leadership, she always took interest in ways. I first knew her in the 1960s —Rosalie Crouch, Ph.D., what I was working on and was unbelievably generous in providing her counsel when I was a medical student. We Provost Emeritus, Distinguished University and review of grants and papers I was writing. Her only stake was encouraging and perceived her as a kind and wise Professor, Department of Ophthalmology helping those of us who were “chasing the prize” — knowledge! person. She was that same person in —Ronald K. Mayfield, M.D., all of my contacts with her over the Dr. Maria Buse was a great mentor to Mountain View Clinical Research years. When I was dean, we would visit not only students but also junior faculty. occasionally. I always felt enriched by Maria was always held in the highest One day at an MUSC teaching clinic, Dr. Buse was seeing a patient newly those conversations. I will miss her. regard by all that knew her. She had diagnosed with Addison’s disease (adrenal insufficiency). Seeking to comfort the —Layton McCurdy M.D., one of the most prolific research careers man, she reassured him. “You’ll be fine. In fact, many great people had the same Dean Emeritus, College of Medicine, in the history of MUSC and had the disease, and they did fine. President Kennedy [John F. Kennedy] had it.” Surprised, Distinguished University Professor record for the longest continuous NIH the patient asked, “Really?” Buse replied, “Yes, and don’t worry. That’s not what RO1 grant. She may have been short in killed him.” Dr. Maria Buse was such an physical stature, but she was a giant in For those of us who have been privileged to know Dr. Buse and to learn from inspiration. She was dedicated, focused stature on our campus. She will long be her teaching and example, this story, as many others, is representative of the and had such a passion for research. remembered for all she did for so many mixture of kindness, compassion and humor that endeared her to the thousands Dr. Maria Buse was a well–renowned and the university. of scientists and clinicians fortunate enough to have crossed her path. Many things researcher in the field of diabetes. I am —Perry V. Halushka, M.D, Ph.D., will be said about the accomplishments, awards and acknowledgments achieved by fortunate to have known her husband, Dean Emeritus, College of Graduate Studies, this brilliant scientist. Many stories will be shared about her gentleness, integrity Dr. John Buse; her children, John, Distinguished University Professor and compassion. Yet, to me, one aspect of her amazing life sets her apart, beyond Paul and Elizabeth; and her. Dr. Maria even the greatest of scientists: the passionate inquisitiveness of her brilliant mind. Buse was a true trailblazer in diabetes Dr. Maria Buse was a true original, and it I remember one day asking her what attribute she thought was most important research and was a woman who was was my privilege to work for 28 years in in a scientist. She reflected on the story of Alexander Fleming, who saved millions well-respected and admired. Her spirit her research lab. She was a brilliant and of lives by his discovery of penicillin in 1928. Fleming was studying the influenza will live on in all the lives she touched! dedicated scientist and clinician. As an virus, not antibiotics. Upon returning from vacation, he found that some of the —Kathie Hermayer, M.D., investigator, her thirst for knowledge and culture plates were contaminated by mold, and that mold had killed bacteria. Dr. Division of Endocrinology, Diabetes and truth was unquenchable. She initiated Buse went on to say, “Most scientists would just ignore the finding, or even fire the Medical Genetics collaborations with faculty across the lab technician, but [Fleming] saw something interesting, and he pursued it. And university and researchers around the here we are.” I will be forever grateful to Dr. Buse for many things, but most of all, Dr. Maria Buse was a brilliant scientist world and inspired others with her for how she helped me see the beauty of an open, eager mind. I hope that now, who broke down barriers for women enthusiasm for discovery. Thanks to her free of all physical limitations, she is in the presence of God, discovering all the choosing to follow in her footsteps. passion for research, she was an excellent secrets of the universe, and that with her characteristic smile, she is saying, “Huh, She was an inspiration to all who mentor to the many students, post docs how interesting.” met her, and her legacy will live on and technicians who trained in her lab. –Sherif Yacoub, M.D., through the many individuals that Their careers and scientific contributions Charleston area endocrinologist she personally mentored throughout are a testament to everything they her career. I know that I will never learned from her and her tenacious forget her and the tremendous impact advocacy on their behalf. I consider she made on science and health care myself fortunate to have known such an during her career. intelligent, kind, humble and inspiring —Lisa K. Saladin, P.T., Ph.D., woman. Dr. Maria Buse will always be Executive vice president for Academic remembered as a pillar of MUSC and Affairs and provost the greater scientific community. —Katherine A. Robinson, Division of Maria was a friend as well as a Endocrinology, Diabetes and Medical scientific colleague and collaborator. Genetics, College of Medicine Among the things we shared were graduate students, co–authored I had the joy and honor of working papers, grants and family dinners. She along with Dr. Maria (our name for OFFICE LOCATIONS IN MT.PLEASANT AND WEST ASHLEY IP03-1777117-1 12 mUsC CAtAlyst news, September 20, 2019
innovAtors Continued from Page Nine for his vision and mentorship and Christine Holmstedt, D.O., for her Impact —Today, we have 28 providers in leadership and dedication to growing the our call pool covering over 35 locations. program and improving access to care These providers respond within 5 and outcomes for the citizens of South minutes and exceed national time Carolina. I also want to acknowledge benchmarks for stroke treatment. We all of the providers, the MUSC Admit expect to perform over 7,000 telestroke Transfer Center staff and especially the consults in South Carolina this year. We telehealth nurse coordinators, who make also offer a scheduled in–patient neuro it all happen 24/7/365. consult service to enable rural hospitals to treat and keep patients locally. Please save the date for Innovation Recognition — Robert J. Adams, M.D., Week 2020 to be held May 4–8, 2020.
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