DOCSLIB.ORG
Explore
Sign Up
Log In
Upload
Search
Home
» Tags
» Wee1
Wee1
Clinical Candidates Targeting the ATR–CHK1–WEE1 Axis in Cancer
Wee1 Rather Than Plk1 Is Inhibited by AZD1775 at Therapeutically Relevant Concentrations
Application of a MYC Degradation
Therapeutic Co-Targeting of WEE1 and ATM Downregulates PD-L1 Expression in Pancreatic Cancer
A Haploid Genetic Screen Identifies the G1/S Regulatory Machinery As a Determinant of Wee1 Inhibitor Sensitivity
CPTC-CDK1-1 (CAB079974) Immunohistochemistry
Functional Genetic Screen Identifies Increased Sensitivity to WEE1 Inhibition in Cells with Defects in Fanconi Anemia and HR Pathways
Targeting the WEE1 Kinase As a Molecular Targeted Therapy for Gastric Cancer
Synergy of WEE1 and Mtor Inhibition in Mutant KRAS-Driven
Regulation of the Cell Cycle and DNA Damage-Induced Checkpoint Activation
Torin1-Mediated TOR Kinase Inhibition Reduces Wee1 Levels And
WEE1 Kinase Targeting Combined with DNA-Damaging Cancer Therapy Catalyzes Mitotic Catastrophe
A Small-Molecule Inhibitor of Wee1, Azd1775, As a Chemosensitizing
Defining the KRAS-Regulated Kinome in KRAS-Mutant Pancreatic Cancer
Cyclin-Dependent Kinase (CDK) Phosphorylation Destabilizes Somatic Wee1 Via Multiple Pathways
The CDK1 Inhibitory Kinase MYT1 in DNA Damage Checkpoint Recovery
Cell Cycle Arrest Through Indirect Transcriptional Repression by P53: I Have a DREAM
A Haploid Genetic Screen Identifies the G1/S Regulatory Machinery As a Determinant of Wee1 Inhibitor Sensitivity
Top View
Chemogenetic Profiling Identifies RAD17 As Synthetically Lethal with Checkpoint Kinase Inhibition
Exploring the Regulation and Function of Human Lats1 and Aurora a Kinases in Mitosis Thesis Advisor: Prof Nigg E.A., Dr
The Roles of Cyclin-Dependent Kinases in Cell-Cycle Progression and Therapeutic Strategies in Human Breast Cancer
Identification of Aurora Kinase B and Wee1-Like Protein Kinase As
Targeted Therapies for Pancreatic Cancer: Overview of Current Treatments and New Opportunities for Personalized Oncology
A Regimen Combining the Wee1 Inhibitor AZD1775 with HDAC Inhibitors Targets Human Acute Myeloid Leukemia Cells Harboring Various Genetic Mutations
WEE1 Kinase Inhibition Enhances the Radiation Response of Diffuse Intrinsic Pontine Gliomas
Inhibition of AAK1 Kinase As a Novel Therapeutic Approach to Treat Neuropathic Pain S
Identification of Wee1 As a Novel Therapeutic Target for Mutant RAS
Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways
Essential Role of the Histone Lysine Demethylase KDM4A in the Biology of Malignant Pleural Mesothelioma (MPM)
Association of CHEK2 Polymorphisms with the Efficacy of Platinum-Based Chemotherapy for Advanced Non-Small-Cell Lung Cancer in Chinese Never-Smoking Women
Chemogenetic Profiling Identifies RAD17 As Synthetically Lethal with Checkpoint Kinase Inhibition
The Role of Hippo Pathway in Mitosis and Cancer
Crosstalk Between the Mtor and DNA Damage Response Pathways in Fission Yeast
1. Introduction 6. Summary 4. Wee1 Selectivity Enhances
Strong Antitumor Synergy Between DNA Crosslinking and HSP90 Inhibition Causes Massive Premitotic DNA Fragmentation in Ovarian Cancer Cells
Wee1 Inhibitor MK1775 Sensitizes KRAS Mutated NSCLC Cells To
CHK2 Inhibition Provides a Strategy to Suppress Hematological Toxicity from PARP Inhibitors
WEE1 Inhibition Enhances Anti-Apoptotic Dependency As a Result of Premature Mitotic Entry and DNA Damage
Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases
Targeted Profiling of RNA Translation Reveals Mtor-4EBP1/2
The Hippo Pathway: a Master Regulatory Network Important in Cancer
Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer Jill J.J
Essay BMS Course Code: WMBM14E001
Structure of Cyclin G-Associated Kinase (GAK)
Page 1 Exploring the Understudied Human Kinome for Research And
TABLE S1: Combination Index Analyses on RPMI-840
Efficacy and Biomarker Analysis of Adavosertib in Differentiated
1 Molecular Pathways WEE1 Kinase Targeting Combined with DNA
Original Article Mtor Inhibition Overcomes Primary and Acquired Resistance to Wee1 Inhibition by Augmenting Replication Stress in Epithelial Ovarian Cancers
Targeting Replicative Stress and DNA Repair by Combining PARP
R-Loop-Induced P21 Expression Following CDC73, CTR9, and PAF1 Loss Protects Cancer Cells Against Replicative Catastrophe Following WEE1 Inhibition
A PIM-CHK1 Signaling Pathway Regulates PLK1 Phosphorylation
Cell-Type-Specific Role of CHK2 in Mediating DNA Damage-Induced
Synergy of WEE1 and Mtor Inhibition in Mutant KRAS-Driven Lung Cancers
PKMYT1: a Forgotten Member of the WEE1 Family