Solution means any aqueous or organic solutions, slurries, viscous solutions, suspensions, emulsions, or pastes.

State means any State of the United States, the District of Columbia, the Commonwealth of Puerto Rico, Guam, American Samoa, the United States Virgin Islands, the Northern Mariana Islands, any other territory or possession over which the United States has jurisdiction and Indian Country.

Threshold planning quantity means, for a substance listed in Appendices A and B of this part, the quantity listed in the column “threshold planning quantity” for that substance.

[73 FR 65462, Nov. 3, 2008, as amended at 73 FR 76960, Dec. 18, 2008; 77 FR 16688, Mar. 22, 2012]

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Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities

[Alphabetical Order]

Reportable Threshold planning CAS quantity* quantity No. Chemical name Notes (pounds) (pounds) 75­86­5 Acetone Cyanohydrin 10 1,000 1752­ Acetone Thiosemicarbazide 1,000 1,000/10,000 30­3 107­02­ Acrolein 1 500 8 79­06­1 Acrylamide f 5,000 1,000/10,000 107­13­ Acrylonitrile f 100 10,000 1 814­68­ Acrylyl Chloride d 100 100 6 111­69­3 Adiponitrile f 1,000 1,000 116­06­3 Aldicarb b 1 100/10,000 309­00­ Aldrin 1 500/10,000 2 107­18­ Allyl Alcohol 100 1,000 6 107­11­9 Allylamine 500 500 20859­ Aluminum Phosphide a 100 500 73­8 54­62­6 Aminopterin 500 500/10,000 78­53­5 Amiton 500 500 3734­ Amiton Oxalate 100 100/10,000 97­2 7664­ Ammonia f 100 500 41­7 300­62­ Amphetamine 1,000 1,000 9 62­53­3 Aniline f 5,000 1,000 88­05­1 Aniline, 2,4,6­Trimethyl­ 500 500 7783­ Antimony Pentafluoride 500 500 70­2 1397­ Antimycin A b 1,000 1,000/10,000 94­0 86­88­4 ANTU 100 500/10,000 1303­ Arsenic Pentoxide 1 100/10,000 28­2 1327­ Arsenous Oxide d 1 100/10,000 53­3 7784­ Arsenous Trichloride 1 500 34­1 7784­ Arsine 100 100 42­1 2642­ Azinphos­Ethyl 100 100/10,000 71­9 86­50­0 Azinphos­Methyl 1 10/10,000 98­87­3 Benzal Chloride 5,000 500 98­16­8 Benzenamine, 3­(Trifluoromethyl)­ 500 500 100­14­ Benzene, 1­(Chloromethyl)­4­Nitro­ 500 500/10,000 1 98­05­5 Benzenearsonic Acid 10 10/10,000 3615­ Benzimidazole, 4,5­Dichloro­2­(Trifluoromethyl)­ c 500 500/10,000 21­2 98­07­7 Benzotrichloride 10 100 100­44­ Benzyl Chloride 100 500 7 140­29­ Benzyl Cyanide d 500 500 4 15271­ Bicyclo[2.2.1]Heptane­2­Carbonitrile, 5­Chloro­6­((((Methylamino)Carbonyl)Oxy)Imino)­, (1s­(1­ 500 500/10,000 41­7 alpha,2­beta,4­alpha,5­alpha,6E))­ 534­07­ Bis(Chloromethyl) Ketone 10 10/10,000 6 4044­ Bitoscanate 500 500/10,000 65­9 10294­ Boron Trichloride 500 500 34­5 7637­ Boron Trifluoride 500 500 07­2 353­42­ Boron Trifluoride Compound With Methyl Ether (1:1) 1,000 1,000 4 28772­ Bromadiolone 100 100/10,000 56­7 7726­ Bromine f 500 500 95­6 1306­ Cadmium Oxide 100 100/10,000 19­0 2223­ Cadmium Stearate b 1,000 1,000/10,000 93­0 7778­ Calcium Arsenate 1 500/10,000 44­1 8001­ Camphechlor 1 500/10,000 35­2 56­25­7 Cantharidin 100 100/10,000 51­83­2 Carbachol Chloride 500 500/10,000 26419­ Carbamic Acid, Methyl­, O­(((2,4­Dimethyl­1, 3­Dithiolan­2­yl)Methylene)Amino)­ 100 100/10,000 73­8 1563­ Carbofuran 10 10/10,000 66­2 75­15­0 Carbon Disulfide f 100 10,000 786­19­ Carbophenothion 500 500 6 57­74­9 Chlordane 1 1,000 470­90­ Chlorfenvinfos 500 500 6 7782­ Chlorine 10 100 50­5 24934­ Chlormephos 500 500 91­6 999­81­ Chlormequat Chloride d 100 100/10,000 5 79­11­8 Chloroacetic Acid 100 100/10,000 107­07­ Chloroethanol 500 500 3 627­11­2 Chloroethyl Chloroformate 1,000 1,000 67­66­3 Chloroform f 10 10,000 542­88­ Chloromethyl Ether d 10 100 1 107­30­ Chloromethyl Methyl Ether b 10 100 2 3691­ Chlorophacinone 100 100/10,000 35­8 1982­ Chloroxuron 500 500/10,000 47­4 21923­ Chlorthiophos d 500 500 23­9 10025­ Chromic Chloride 1 1/10,000 73­7 62207­ Cobalt, ((2,2′­(1,2­Ethanediylbis (Nitrilomethylidyne)) Bis(6­Fluorophenolato))(2­)­N,N′,O,O′)­ 100 100/10,000 76­5 10210­ Cobalt Carbonyl d 10 10/10,000 68­1 64­86­8 Colchicine d 10 10/10,000 56­72­4 Coumaphos 10 100/10,000 5836­ Coumatetralyl 500 500/10,000 29­3 95­48­7 Cresol, o­ 100 1,000/10,000 535­89­ Crimidine 100 100/10,000 7 4170­ Crotonaldehyde 100 1,000 30­3 123­73­ Crotonaldehyde, (E)­ 100 1,000 9 506­68­ Cyanogen Bromide 1,000 500/10,000 3 506­78­ Cyanogen Iodide 1,000 1,000/10,000 5 2636­ Cyanophos 1,000 1,000 26­2 675­14­ Cyanuric Fluoride 100 100 9 66­81­9 Cycloheximide 100 100/10,000 108­91­ Cyclohexylamine f 10,000 10,000 8 17702­ Decaborane(14) 500 500/10,000 41­9 8065­ Demeton 500 500 48­3 919­86­ Demeton­S­Methyl 500 500 8 10311­ Dialifor 100 100/10,000 84­9 19287­ Diborane 100 100 45­7 111­44­4 Dichloroethyl ether 10 10,000 149­74­ Dichloromethylphenylsilane 1,000 1,000 6 62­73­7 Dichlorvos 10 1,000 141­66­ Dicrotophos 100 100 2 1464­ Diepoxybutane 10 500 53­5 814­49­ Diethyl Chlorophosphate d 500 500 3 71­63­6 Digitoxin b 100 100/10,000 2238­ Diglycidyl Ether 1,000 1,000 07­5 20830­ Digoxin d 10 10/10,000 75­5 115­26­4 Dimefox 500 500 60­51­5 Dimethoate 10 500/10,000 2524­ Dimethyl Phosphorochloridothioate 500 500 03­0 77­78­1 Dimethyl sulfate 100 500 75­78­5 Dimethyldichlorosilane d 500 500 57­14­7 Dimethylhydrazine 10 1,000 99­98­9 Dimethyl­p­Phenylenediamine 10 10/10,000 644­64­ Dimetilan 1 500/10,000 4 534­52­ Dinitrocresol 10 10/10,000 1 88­85­7 Dinoseb 1,000 100/10,000 1420­ Dinoterb 500 500/10,000 07­1 78­34­2 Dioxathion 500 500 82­66­6 Diphacinone 10 10/10,000 152­16­ Diphosphoramide, Octamethyl­ 100 100 9 298­04­ Disulfoton 1 500 4 514­73­ Dithiazanine Iodide 500 500/10,000 8 541­53­ Dithiobiuret 100 100/10,000 7 316­42­ Emetine, Dihydrochloride d 1 1/10,000 7 115­29­7 Endosulfan 1 10/10,000 2778­ Endothion 500 500/10,000 04­3 72­20­8 Endrin 1 500/10,000 106­89­ Epichlorohydrin f 100 1,000 8 2104­ EPN 100 100/10,000 64­5 50­14­6 Ergocalciferol b 1,000 1,000/10,000 379­79­ Ergotamine Tartrate 500 500/10,000 3 1622­ Ethanesulfonyl Chloride, 2­Chloro­ 500 500 32­8 10140­ Ethanol, 1,2­Dichloro­, Acetate 1,000 1,000 87­1 563­12­ Ethion 10 1,000 2 13194­ Ethoprophos 1,000 1,000 48­4 538­07­ Ethylbis(2­Chloroethyl)Amine d 500 500 8 371­62­ Ethylene Fluorohydrin b, d 10 10 0 75­21­8 Ethylene Oxide f 10 1,000 107­15­ Ethylenediamine 5,000 10,000 3 151­56­ Ethyleneimine 1 500 4 542­90­ Ethylthiocyanate 10,000 10,000 5 22224­ Fenamiphos 10 10/10,000 92­6 115­90­2 Fensulfothion d 500 500 4301­ Fluenetil 100 100/10,000 50­2 7782­ Fluorine e 10 500 41­4 640­19­ Fluoroacetamide 100 100/10,000 7 144­49­ Fluoroacetic Acid 10 10/10,000 0 359­06­ Fluoroacetyl Chloride b 10 10 8 51­21­8 Fluorouracil 500 500/10,000 944­22­ Fonofos 500 500 9 50­00­0 Formaldehyde f 100 500 107­16­ Formaldehyde Cyanohydrin d 1,000 1,000 4 23422­ Formetanate Hydrochloride d 100 500/10,000 53­9 2540­ Formothion 100 100 82­1 17702­ Formparanate 100 100/10,000 57­7 21548­ Fosthietan 500 500 32­3 3878­ Fuberidazole 100 100/10,000 19­1 110­00­9 Furan 100 500 13450­ Gallium Trichloride 500 500/10,000 90­3 77­47­4 Hexachlorocyclopentadiene d 10 100 4835­11­ Hexamethylenediamine, N,N′­Dibutyl­ 500 500 4 302­01­ Hydrazine 1 1,000 2 74­90­8 Hydrocyanic Acid 10 100 7647­ Hydrogen Chloride (gas only) f 5,000 500 01­0 7664­ Hydrogen Fluoride 100 100 39­3 7722­ Hydrogen Peroxide (Conc >52%) f 1,000 1,000 84­1 7783­ Hydrogen Selenide 10 10 07­5 7783­ Hydrogen Sulfide f 100 500 06­4 123­31­ Hydroquinone f 100 500/10,000 9 13463­ Iron, Pentacarbonyl­ 100 100 40­6 297­78­ Isobenzan 100 100/10,000 9 78­82­0 Isobutyronitrile d 1,000 1,000 102­36­ Isocyanic Acid, 3,4­Dichlorophenyl Ester 500 500/10,000 3 465­73­ Isodrin 1 100/10,000 6 55­91­4 Isofluorphate b 100 100 4098­ Isophorone Diisocyanate g 500 500 71­9 108­23­ Isopropyl Chloroformate 1,000 1,000 6 119­38­0 Isopropylmethyl­pyrazolyl Dimethylcarbamate 100 500 78­97­7 Lactonitrile 1,000 1,000 21609­ Leptophos 500 500/10,000 90­5 541­25­ Lewisite b, d 10 10 3 58­89­9 Lindane 1 1,000/10,000 7580­ Lithium Hydride a 100 100 67­8 109­77­ Malononitrile 1,000 500/10,000 3 12108­ Manganese, Tricarbonyl Methylcyclopentadienyl d 100 100 13­3 51­75­2 Mechlorethamine b 10 10 950­10­ Mephosfolan 500 500 7 1600­ Mercuric Acetate 500 500/10,000 27­7 7487­ Mercuric Chloride 500 500/10,000 94­7 21908­ Mercuric Oxide 500 500/10,000 53­2 10476­ Methacrolein Diacetate 1,000 1,000 95­6 760­93­ Methacrylic Anhydride 500 500 0 126­98­ Methacrylonitrile d 1,000 500 7 920­46­ Methacryloyl Chloride 100 100 7 30674­ Methacryloyloxyethyl Isocyanate d 100 100 80­7 10265­ Methamidophos 100 100/10,000 92­6 558­25­ Methanesulfonyl Fluoride 1,000 1,000 8 950­37­ Methidathion 500 500/10,000 8 2032­ Methiocarb 10 500/10,000 65­7 16752­ Methomyl d 100 500/10,000 77­5 151­38­ Methoxyethylmercuric Acetate 500 500/10,000 2 80­63­7 Methyl 2­Chloroacrylate 500 500 74­83­9 Methyl Bromide f 1,000 1,000 79­22­1 Methyl Chloroformate d 1,000 500 60­34­4 Methyl Hydrazine 10 500 624­83­ Methyl Isocyanate 10 500 9 556­61­ Methyl Isothiocyanate a 500 500 6 74­93­1 Methyl Mercaptan f 100 500 3735­ Methyl Phenkapton 500 500 23­7 676­97­ Methyl Phosphonic Dichloride a 100 100 1 556­64­ Methyl Thiocyanate 10,000 10,000 9 78­94­4 Methyl Vinyl Ketone 10 10 502­39­ Methylmercuric Dicyanamide 500 500/10,000 6 75­79­6 Methyltrichlorosilane d 500 500 1129­41­ Metolcarb 1,000 100/10,000 5 7786­ Mevinphos 10 500 34­7 315­18­ Mexacarbate d 1,000 500/10,000 4 50­07­7 Mitomycin C 10 500/10,000 6923­ Monocrotophos 10 10/10,000 22­4 2763­ Muscimol 1,000 500/10,000 96­4 505­60­ Mustard Gas d 500 500 2 13463­ Nickel Carbonyl 10 1 39­3 54­11­5 Nicotine b 100 100 65­30­5 Nicotine Sulfate 100 100/10,000 7697­ Nitric Acid 1,000 1,000 37­2 10102­ Nitric Oxide b 10 100 43­9 98­95­3 Nitrobenzene f 1,000 10,000 1122­60­ Nitrocyclohexane 500 500 7 10102­ Nitrogen Dioxide 10 100 44­0 62­75­9 Nitrosodimethylamine d 10 1,000 991­42­ Norbormide 100 100/10,000 4 Organorhodium Complex (PMN­82­147) 10 10/10,000 630­60­ Ouabain b 100 100/10,000 4 23135­ Oxamyl 100 100/10,000 22­0 78­71­7 Oxetane, 3,3­Bis(Chloromethyl)­ 500 500 2497­ Oxydisulfoton d 500 500 07­6 10028­ Ozone 100 100 15­6 1910­ Paraquat Dichloride 10 10/10,000 42­5 2074­ Paraquat Methosulfate 10 10/10,000 50­2 56­38­2 Parathion b 10 100 298­00­ Parathion­Methyl b 100 100/10,000 0 12002­ Paris Green 1 500/10,000 03­8 19624­ Pentaborane 500 500 22­7 2570­ Pentadecylamine 100 100/10,000 26­5 79­21­0 Peracetic Acid 500 500 594­42­ Perchloromethylmercaptan 100 500 3 108­95­ Phenol 1,000 500/10,000 2 4418­ Phenol, 2,2′­Thiobis(4­Chloro­6­Methyl)­ 100 100/10,000 66­0 64­00­6 Phenol, 3­(1­Methylethyl)­, Methylcarbamate 10 500/10,000 58­36­6 Phenoxarsine, 10,10′­Oxydi­ 500 500/10,000 696­28­ Phenyl Dichloroarsine d 1 500 6 59­88­1 Phenylhydrazine Hydrochloride 1,000 1,000/10,000 62­38­4 Phenylmercury Acetate 100 500/10,000 2097­ Phenylsilatrane d 100 100/10,000 19­0 103­85­ Phenylthiourea 100 100/10,000 5 298­02­ Phorate 10 10 2 4104­ Phosacetim 100 100/10,000 14­7 947­02­ Phosfolan 100 100/10,000 4 75­44­5 Phosgene f 10 10 13171­ Phosphamidon 100 100 21­6 7803­ Phosphine 100 500 51­2 2703­ Phosphonothioic Acid, Methyl­, O­Ethyl O­(4­(Methylthio) Phenyl) Ester 500 500 13­1 50782­ Phosphonothioic Acid, Methyl­, S­(2­(Bis(1Methylethyl)Amino)Ethyl) O­Ethyl Ester 100 100 69­9 2665­ Phosphonothioic Acid, Methyl­, O­(4­Nitrophenyl) O­Phenyl Ester 500 500 30­7 3254­ Phosphoric Acid, Dimethyl 4­(Methylthio)Phenyl Ester 500 500 63­5 2587­ Phosphorothioic Acid, O,O­Dimethyl­S­(2­Methylthio) Ethyl Ester b, c 500 500 90­8 7723­ Phosphorus a, d 1 100 14­0 10025­ Phosphorus Oxychloride 1,000 500 87­3 10026­ Phosphorus Pentachloride a 500 500 13­8 7719­ Phosphorus Trichloride 1,000 1,000 12­2 57­47­6 Physostigmine 100 100/10,000 57­64­7 Physostigmine, Salicylate (1:1) 100 100/10,000 124­87­ Picrotoxin 500 500/10,000 8 110­89­4 Piperidine 1,000 1,000 23505­ Pirimifos­Ethyl 1,000 1,000 41­1 10124­ Potassium Arsenite 1 500/10,000 50­2 151­50­ Potassium Cyanide a 10 100 8 506­61­ Potassium Silver Cyanide a 1 500 6 2631­ Promecarb d 1,000 500/10,000 37­0 106­96­ Propargyl Bromide 10 10 7 57­57­8 Propiolactone, Beta­ 10 500 107­12­ Propionitrile 10 500 0 542­76­ Propionitrile, 3­Chloro­ 1,000 1,000 7 70­69­9 Propiophenone, 4­Amino­ c 100 100/10,000 109­61­ Propyl Chloroformate 500 500 5 75­56­9 Propylene Oxide f 100 10,000 75­55­8 Propyleneimine 1 10,000 2275­ Prothoate 100 100/10,000 18­5 129­00­ Pyrene b 5,000 1,000/10,000 0 140­76­ Pyridine, 2­Methyl­5­Vinyl­ 500 500 1 504­24­ Pyridine, 4­Amino­ d 1,000 500/10,000 5 1124­33­ Pyridine, 4­Nitro­,l­Oxide 500 500/10,000 0 53558­ Pyriminil d 100 100/10,000 25­1 14167­ Salcomine 500 500/10,000 18­1 107­44­ Sarin d 10 10 8 7783­ Selenious Acid 10 1,000/10,000 00­8 7791­ Selenium Oxychloride 500 500 23­3 563­41­ Semicarbazide Hydrochloride 1,000 1,000/10,000 7 3037­ Silane, (4­Aminobutyl)Diethoxymethyl­ 1,000 1,000 72­7 7631­ Sodium Arsenate 1 1,000/10,000 89­2 7784­ Sodium Arsenite 1 500/10,000 46­5

26628­ Sodium Azide (Na(N3)) a 1,000 500 22­8 124­65­ Sodium Cacodylate 100 100/10,000 2 143­33­ Sodium Cyanide (Na(CN)) a 10 100 9 62­74­8 Sodium Fluoroacetate 10 10/10,000 13410­ Sodium Selenate 100 100/10,000 01­0 10102­ Sodium Selenite d 100 100/10,000 18­8 10102­ Sodium Tellurite 500 500/10,000 20­2 900­95­ Stannane, Acetoxytriphenyl­ c 500 500/10,000 8 57­24­9 Strychnine b 10 100/10,000 60­41­3 Strychnine Sulfate 10 100/10,000 3689­ Sulfotep 100 500 24­5 3569­ Sulfoxide, 3­Chloropropyl Octyl 500 500 57­1 7446­ Sulfur Dioxide f 500 500 09­5 7783­ Sulfur Tetrafluoride 100 100 60­0 7446­11­ Sulfur Trioxide a 100 100 9 7664­ Sulfuric Acid 1,000 1,000 93­9 77­81­6 Tabun b, d 10 10 7783­ Tellurium Hexafluoride e 100 100 80­4 107­49­ TEPP 10 100 3 13071­ Terbufos d 100 100 79­9 78­00­2 Tetraethyllead b 10 100 597­64­ Tetraethyltin b 100 100 8 75­74­1 Tetramethyllead b, f 100 100 509­14­ Tetranitromethane 10 500 8 10031­ Thallium Sulfate d 100 100/10,000 59­1 6533­ Thallous Carbonate b, d 100 100/10,000 73­9 7791­ Thallous Chloride b, d 100 100/10,000 12­0 2757­ Thallous Malonate b, d 100 100/10,000 18­8 7446­ Thallous Sulfate 100 100/10,000 18­6 2231­ Thiocarbazide 1,000 1,000/10,000 57­4 39196­ Thiofanox 100 100/10,000 18­4 297­97­ Thionazin 100 500 2 108­98­ Thiophenol 100 500 5 79­19­6 Thiosemicarbazide 100 100/10,000 5344­ Thiourea, (2­Chlorophenyl)­ 100 100/10,000 82­1 614­78­ Thiourea, (2­Methylphenyl)­ 500 500/10,000 8 7550­ Titanium Tetrachloride 1,000 100 45­0 584­84­ Toluene 2,4­Diisocyanate 100 500 9 91­08­7 Toluene 2,6­Diisocyanate 100 100 110­57­6 Trans­1,4­Dichlorobutene 500 500 1031­ Triamiphos 500 500/10,000 47­6 24017­ Triazofos 500 500 47­8 76­02­8 Trichloroacetyl Chloride 500 500 115­21­9 Trichloroethylsilane d 500 500 327­98­ Trichloronate e 500 500 0 98­13­5 Trichlorophenylsilane d 500 500 1558­ Trichloro(Chloromethyl)Silane 100 100 25­4 27137­ Trichloro(Dichlorophenyl) Silane 500 500 85­5 998­30­ Triethoxysilane 500 500 1 75­77­4 Trimethylchlorosilane 1,000 1,000 824­11­3 Trimethylolpropane Phosphite d 100 100/10,000 1066­ Trimethyltin Chloride 500 500/10,000 45­1 639­58­ Triphenyltin Chloride 500 500/10,000 7 555­77­ Tris(2­Chloroethyl)Amine d 100 100 1 2001­ Valinomycin b 1,000 1,000/10,000 95­8 1314­ Vanadium Pentoxide 1,000 100/10,000 62­1 108­05­ Vinyl Acetate Monomer f 5,000 1,000 4 81­81­2 Warfarin 100 500/10,000 129­06­ Warfarin Sodium d 100 100/10,000 6 28347­ Xylylene Dichloride 100 100/10,000 13­9 58270­ Zinc, Dichloro(4,4­Dimethyl­5((((Methylamino)Carbonyl) Oxy)Imino)Pentanenitrile)­, (T­4)­ 100 100/10,000 08­9 1314­ Zinc Phosphide a 100 500 84­7

*Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.

Notes:

a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non­powder, non­molten, non­ solution form.

b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.

c. Chemicals added by final rule, April 22, 1987.

d. Revised TPQ based on new or re­evaluated toxicity data, April 22, 1987.

e. The TPQ was revised due to calculation error, April 22, 1987.

f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”), November 17, 1986 and February 15, 1990.

g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987 final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.

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Appendix B to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities

[CAS Number Order]

Reportable Threshold planning CAS quantity* quantity No. Chemical name Notes (pounds) (pounds) 0 Organorhodium Complex (PMN­82­147) 10 10/10,000 50­00­0 Formaldehyde f 100 500 50­07­7 Mitomycin C 10 500/10,000 50­14­6 Ergocalciferol b 1,000 1,000/10,000 51­21­8 Fluorouracil 500 500/10,000 51­75­2 Mechlorethamine b 10 10 51­83­2 Carbachol Chloride 500 500/10,000 54­11­5 Nicotine b 100 100 54­62­6 Aminopterin 500 500/10,000 55­91­4 Isofluorphate b 100 100 56­25­7 Cantharidin 100 100/10,000 56­38­2 Parathion b 10 100 56­72­4 Coumaphos 10 100/10,000 57­14­7 Dimethylhydrazine 10 1,000 57­24­9 Strychnine b 10 100/10,000 57­47­6 Physostigmine 100 100/10,000 57­57­8 Propiolactone, Beta­ 10 500 57­64­7 Physostigmine, Salicylate (1:1) 100 100/10,000 57­74­9 Chlordane 1 1,000 58­36­6 Phenoxarsine, 10,10′­Oxydi­ 500 500/10,000 58­89­9 Lindane 1 1,000/10,000 59­88­1 Phenylhydrazine Hydrochloride 1,000 1,000/10,000 60­34­4 Methyl Hydrazine 10 500 60­41­3 Strychnine sulfate 10 100/10,000 60­51­5 Dimethoate 10 500/10,000 62­38­4 Phenylmercury Acetate 100 500/10,000 62­53­3 Aniline f 5,000 1,000 62­73­7 Dichlorvos 10 1,000 62­74­8 Sodium Fluoroacetate 10 10/10,000 62­75­9 Nitrosodimethylamine d 10 1,000 64­00­6 Phenol, 3­(1­Methylethyl)­, Methylcarbamate 10 500/10,000 64­86­8 Colchicine d 10 10/10,000 65­30­5 Nicotine sulfate 100 100/10,000 66­81­9 Cycloheximide 100 100/10,000 67­66­3 Chloroform f 10 10,000 70­69­9 Propiophenone, 4­Amino­ c 100 100/10,000 71­63­6 Digitoxin b 100 100/10,000 72­20­8 Endrin 1 500/10,000 74­83­9 Methyl Bromide f 1,000 1,000 74­90­8 Hydrocyanic Acid 10 100 74­93­1 Methyl Mercaptan f 100 500 75­15­0 Carbon Disulfide f 100 10,000 75­21­8 Ethylene Oxide f 10 1,000 75­44­5 Phosgene f 10 10 75­55­8 Propyleneimine 1 10,000 75­56­9 Propylene Oxide f 100 10,000 75­74­1 Tetramethyllead b, f 100 100 75­77­4 Trimethylchlorosilane 1,000 1,000 75­78­5 Dimethyldichlorosilane d 500 500 75­79­6 Methyltrichlorosilane d 500 500 75­86­5 Acetone Cyanohydrin 10 1,000 76­02­8 Trichloroacetyl Chloride 500 500 77­47­4 Hexachlorocyclopentadiene d 10 100 77­78­1 Dimethyl Sulfate 100 500 77­81­6 Tabun b, d 10 10 78­00­2 Tetraethyllead b 10 100 78­34­2 Dioxathion 500 500 78­53­5 Amiton 500 500 78­71­7 Oxetane, 3,3­Bis(Chloromethyl)­ 500 500 78­82­0 Isobutyronitrile d 1,000 1,000 78­94­4 Methyl Vinyl Ketone 10 10 78­97­7 Lactonitrile 1,000 1,000 79­06­1 Acrylamide f 5,000 1,000/10,000 79­11­8 Chloroacetic Acid 100 100/10,000 79­19­6 Thiosemicarbazide 100 100/10,000 79­21­0 Peracetic Acid 500 500 79­22­1 Methyl Chloroformate d 1,000 500 80­63­7 Methyl 2­Chloroacrylate 500 500 81­81­2 Warfarin 100 500/10,000 82­66­6 Diphacinone 10 10/10,000 86­50­0 Azinphos­Methyl 1 10/10,000 86­88­4 ANTU 100 500/10,000 88­05­1 Aniline, 2,4,6­Trimethyl­ 500 500 88­85­7 Dinoseb 1,000 100/10,000 91­08­7 Toluene 2,6­Diisocyanate 100 100 95­48­7 Cresol, o­ 100 1,000/10,000 98­05­5 Benzenearsonic Acid 10 10/10,000 98­07­7 Benzotrichloride 10 100 98­13­5 Trichlorophenylsilane d 500 500 98­16­8 Benzenamine, 3­(Trifluoromethyl)­ 500 500 98­87­3 Benzal Chloride 5,000 500 98­95­3 Nitrobenzene f 1,000 10,000 99­98­9 Dimethyl­p­Phenylenediamine 10 10/10,000 100­14­ Benzene, 1­(Chloromethyl)­4­Nitro­ 500 500/10,000 1 100­44­ Benzyl Chloride 100 500 7 102­36­ Isocyanic Acid, 3,4­Dichlorophenyl Ester 500 500/10,000 3 103­85­ Phenylthiourea 100 100/10,000 5 106­89­ Epichlorohydrin f 100 1,000 8 106­96­ Propargyl Bromide 10 10 7 107­02­ Acrolein 1 500 8 107­07­ Chloroethanol 500 500 3 107­11­9 Allylamine 500 500 107­12­ Propionitrile 10 500 0 107­13­ Acrylonitrile f 100 10,000 1 107­15­ Ethylenediamine 5,000 10,000 3 107­16­ Formaldehyde Cyanohydrin d 1,000 1,000 4 107­18­ Allyl Alcohol 100 1,000 6 107­30­ Chloromethyl Methyl Ether b 10 100 2 107­44­ Sarin d 10 10 8 107­49­ TEPP 10 100 3 108­05­ Vinyl Acetate Monomer f 5,000 1,000 4 108­23­ Isopropyl Chloroformate 1,000 1,000 6 108­91­ Cyclohexylamine f 10,000 10,000 8 108­95­ Phenol 1,000 500/10,000 2 108­98­ Thiophenol 100 500 5 109­61­ Propyl Chloroformate 500 500 5 109­77­ Malononitrile 1,000 500/10,000 3 110­00­9 Furan 100 500 110­57­6 Trans­1,4­Dichlorobutene 500 500 110­89­4 Piperidine 1,000 1,000 111­44­4 Dichloroethyl Ether 10 10,000 111­69­3 Adiponitrile f 1,000 1,000 115­21­9 Trichloroethylsilane d 500 500 115­26­4 Dimefox 500 500 115­29­7 Endosulfan 1 10/10,000 115­90­2 Fensulfothion d 500 500 116­06­3 Aldicarb b 1 100/10,000 119­38­0 Isopropylmethyl­pyrazolyl Dimethylcarbamate 100 500 123­31­ Hydroquinone f 100 500/10,000 9 123­73­ Crotonaldehyde, (E)­ 100 1,000 9 124­65­ Sodium Cacodylate 100 100/10,000 2 124­87­ Picrotoxin 500 500/10,000 8 126­98­ Methacrylonitrile d 1,000 500 7 129­00­ Pyrene b 5,000 1,000/10,000 0 129­06­ Warfarin Sodium d 100 100/10,000 6 140­29­ Benzyl Cyanide d 500 500 4 140­76­ Pyridine, 2­Methyl­5­Vinyl­ 500 500 1 141­66­ Dicrotophos 100 100 2 143­33­ Sodium Cyanide (Na(CN)) a 10 100 9 144­49­ Fluoroacetic Acid 10 10/10,000 0 149­74­ Dichloromethylphenylsilane 1,000 1,000 6 151­38­ Methoxyethylmercuric Acetate 500 500/10,000 2 151­50­ Potassium Cyanide a 10 100 8 151­56­ Ethyleneimine 1 500 4 152­16­ Diphosphoramide, Octamethyl­ 100 100 9 297­78­ Isobenzan 100 100/10,000 9 297­97­ Thionazin 100 500 2 298­00­ Parathion­Methyl b 100 100/10,000 0 298­02­ Phorate 10 10 2 298­04­ Disulfoton 1 500 4 300­62­ Amphetamine 1,000 1,000 9 302­01­ Hydrazine 1 1,000 2 309­00­ Aldrin 1 500/10,000 2 315­18­ Mexacarbate 1,000 500/10,000 4 316­42­ Emetine, Dihydrochloride d 1 1/10,000 7 327­98­ Trichloronate e 500 500 0 353­42­ Boron Trifluoride Compound With Methyl Ether (1:1) 1,000 1,000 4 359­06­ Fluoroacetyl Chloride b 10 10 8 371­62­ Ethylene Fluorohydrin b, d 10 10 0 379­79­ Ergotamine Tartrate 500 500/10,000 3 465­73­ Isodrin 1 100/10,000 6 470­90­ Chlorfenvinfos 500 500 6 502­39­ Methylmercuric Dicyanamide 500 500/10,000 6 504­24­ Pyridine, 4­Amino­ d 1,000 500/10,000 5 505­60­ Mustard Gas d 500 500 2 506­61­ Potassium Silver Cyanide a 1 500 6 506­68­ Cyanogen Bromide 1,000 500/10,000 3 506­78­ Cyanogen Iodide 1,000 1,000/10,000 5 509­14­ Tetranitromethane 10 500 8 514­73­ Dithiazanine Iodide 500 500/10,000 8 534­07­ Bis(Chloromethyl) Ketone 10 10/10,000 6 534­52­ Dinitrocresol 10 10/10,000 1 535­89­ Crimidine 100 100/10,000 7 538­07­ Ethylbis(2­Chloroethyl)Amine d 500 500 8 541­25­ Lewisite b, d 10 10 3 541­53­ Dithiobiuret 100 100/10,000 7 542­76­ Propionitrile, 3­Chloro­ 1,000 1,000 7 542­88­ Chloromethyl Ether d 10 100 1 542­90­ Ethylthiocyanate 10,000 10,000 5 555­77­ Tris(2­Chloroethyl)Amine d 100 100 1 556­61­ Methyl Isothiocyanate a 500 500 6 556­64­ Methyl Thiocyanate 10,000 10,000 9 558­25­ Methanesulfonyl Fluoride 1,000 1,000 8 563­12­ Ethion 10 1,000 2 563­41­ Semicarbazide Hydrochloride 1,000 1,000/10,000 7 584­84­ Toluene 2,4­Diisocyanate 100 500 9 594­42­ Perchloromethylmercaptan 100 500 3 597­64­ Tetraethyltin b 100 100 8 614­78­ Thiourea, (2­Methylphenyl)­ 500 500/10,000 8 624­83­ Methyl Isocyanate 10 500 9 627­11­2 Chloroethyl Chloroformate 1,000 1,000 630­60­ Ouabain b 100 100/10,000 4 639­58­ Triphenyltin Chloride 500 500/10,000 7 640­19­ Fluoroacetamide 100 100/10,000 7 644­64­ Dimetilan 1 500/10,000 4 675­14­ Cyanuric Fluoride 100 100 9 676­97­ Methyl Phosphonic Dichloride a 100 100 1 696­28­ Phenyl Dichloroarsine d 1 500 6 760­93­ Methacrylic Anhydride 500 500 0 786­19­ Carbophenothion 500 500 6 814­49­ Diethyl Chlorophosphate d 500 500 3 814­68­ Acrylyl Chloride d 100 100 6 824­11­3 Trimethylolpropane Phosphite d 100 100/10,000 900­95­ Stannane, Acetoxytriphenyl­ c 500 500/10,000 8 919­86­ Demeton­S­Methyl 500 500 8 920­46­ Methacryloyl Chloride 100 100 7 944­22­ Fonofos 500 500 9 947­02­ Phosfolan 100 100/10,000 4 950­10­ Mephosfolan 500 500 7 950­37­ Methidathion 500 500/10,000 8 991­42­ Norbormide 100 100/10,000 4 998­30­ Triethoxysilane 500 500 1 999­81­ Chlormequat Chloride d 100 100/10,000 5 1031­ Triamiphos 500 500/10,000 47­6 1066­ Trimethyltin Chloride 500 500/10,000 45­1 1122­60­ Nitrocyclohexane 500 500 7 1124­33­ Pyridine, 4­Nitro­,1­Oxide 500 500/10,000 0 1129­41­ Metolcarb 1,000 100/10,000 5 1303­ Arsenic Pentoxide 1 100/10,000 28­2 1306­ Cadmium Oxide 100 100/10,000 19­0 1314­ Vanadium Pentoxide 1,000 100/10,000 62­1 1314­ Zinc Phosphide a 100 500 84­7 1327­ Arsenous Oxide d 1 100/10,000 53­3 1397­ Antimycin A b 1,000 1,000/10,000 94­0 1420­ Dinoterb 500 500/10,000 07­1 1464­ Diepoxybutane 10 500 53­5 1558­ Trichloro(Chloromethyl)Silane 100 100 25­4 1563­ Carbofuran 10 10/10,000 66­2 1600­ Mercuric Acetate 500 500/10,000 27­7 1622­ Ethanesulfonyl Chloride, 2­Chloro­ 500 500 32­8 1752­ Acetone Thiosemicarbazide 1,000 1,000/10,000 30­3 1910­ Paraquat Dichloride 10 10/10,000 42­5 1982­ Chloroxuron 500 500/10,000 47­4 2001­ Valinomycin b 1,000 1,000/10,000 95­8 2032­ Methiocarb 10 500/10,000 65­7 2074­ Paraquat Methosulfate 10 10/10,000 50­2 2097­ Phenylsilatrane d 100 100/10,000 19­0 2104­ EPN 100 100/10,000 64­5 2223­ Cadmium Stearate b 1,000 1,000/10,000 93­0 2231­ Thiocarbazide 1,000 1,000/10,000 57­4 2238­ Diglycidyl Ether 1,000 1,000 07­5 2275­ Prothoate 100 100/10,000 18­5 2497­ Oxydisulfoton d 500 500 07­6 2524­ Dimethyl Phosphorochloridothioate 500 500 03­0 2540­ Formothion 100 100 82­1 2570­ Pentadecylamine 100 100/10,000 26­5 2587­ Phosphorothioic Acid, O,O­Dimethyl­S­(2­Methylthio) Ethyl Ester b, c 500 500 90­8 2631­ Promecarb d 1,000 500/10,000 37­0 2636­ Cyanophos 1,000 1,000 26­2 2642­ Azinphos­Ethyl 100 100/10,000 71­9 2665­ Phosphonothioic Acid, Methyl­, O­(4­Nitrophenyl) O­Phenyl Ester 500 500 30­7 2703­ Phosphonothioic Acid, Methyl­, O­Ethyl O­(4­(Methylthio)Phenyl) Ester 500 500 13­1 2757­ Thallous Malonate b, d 100 100/10,000 18­8 2763­ Muscimol 1,000 500/10,000 96­4 2778­ Endothion 500 500/10,000 04­3 3037­ Silane, (4­Aminobutyl)Diethoxymethyl­ 1,000 1,000 72­7 3254­ Phosphoric Acid, Dimethyl 4­(Methylthio)Phenyl Ester 500 500 63­5 3569­ Sulfoxide, 3­Chloropropyl Octyl 500 500 57­1 3615­ Benzimidazole, 4,5­Dichloro­2­(Trifluoromethyl)­ c 500 500/10,000 21­2 3689­ Sulfotep 100 500 24­5 3691­ Chlorophacinone 100 100/10,000 35­8 3734­ Amiton Oxalate 100 100/10,000 97­2 3735­ Methyl Phenkapton 500 500 23­7 3878­ Fuberidazole 100 100/10,000 19­1 4044­ Bitoscanate 500 500/10,000 65­9 4098­ Isophorone Diisocyanate g 500 500 71­9 4104­ Phosacetim 100 100/10,000 14­7 4170­ Crotonaldehyde 100 1,000 30­3 4301­ Fluenetil 100 100/10,000 50­2 4418­ Phenol, 2,2′­Thiobis(4­Chloro­6­Methyl)­ 100 100/10,000 66­0 4835­11­ Hexamethylenediamine, N,N′­Dibutyl­ 500 500 4 5344­ Thiourea, (2­Chlorophenyl)­ 100 100/10,000 82­1 5836­ Coumatetralyl 500 500/10,000 29­3 6533­ Thallous Carbonate b, d 100 100/10,000 73­9 6923­ Monocrotophos 10 10/10,000 22­4 7446­ Sulfur Dioxide f 500 500 09­5 7446­11­ Sulfur Trioxide a 100 100 9 7446­ Thallous Sulfate 100 100/10,000 18­6 7487­ Mercuric Chloride 500 500/10,000 94­7 7550­ Titanium Tetrachloride 1,000 100 45­0 7580­ Lithium Hydride a 100 100 67­8 7631­ Sodium Arsenate 1 1,000/10,000 89­2 7637­ Boron Trifluoride 500 500 07­2 7647­ Hydrogen Chloride (gas only) f 5,000 500 01­0 7664­ Hydrogen Fluoride 100 100 39­3 7664­ Ammonia f 100 500 41­7 7664­ Sulfuric Acid 1,000 1,000 93­9 7697­ Nitric Acid 1,000 1,000 37­2 7719­ Phosphorus Trichloride 1,000 1,000 12­2 7722­ Hydrogen Peroxide (Conc >52%) f 1,000 1,000 84­1 7723­ Phosphorus a, d 1 100 14­0 7726­ Bromine f 500 500 95­6 7778­ Calcium Arsenate 1 500/10,000 44­1 7782­ Fluorine e 10 500 41­4 7782­ Chlorine 10 100 50­5 7783­ Selenious Acid 10 1,000/10,000 00­8 7783­ Hydrogen Sulfide f 100 500 06­4 7783­ Hydrogen Selenide 10 10 07­5 7783­ Sulfur Tetrafluoride 100 100 60­0 7783­ Antimony Pentafluoride 500 500 70­2 7783­ Tellurium Hexafluoride e 100 100 80­4 7784­ Arsenous Trichloride 1 500 34­1 7784­ Arsine 100 100 42­1 7784­ Sodium Arsenite 1 500/10,000 46­5 7786­ Mevinphos 10 500 34­7 7791­ Thallous Chloride b, d 100 100/10,000 12­0 7791­ Selenium Oxychloride 500 500 23­3 7803­ Phosphine 100 500 51­2 8001­ Camphechlor 1 500/10,000 35­2 8065­ Demeton 500 500 48­3 10025­ Chromic Chloride 1 1/10,000 73­7 10025­ Phosphorus Oxychloride 1,000 500 87­3 10026­ Phosphorus Pentachloride a 500 500 13­8 10028­ Ozone 100 100 15­6 10031­ Thallium Sulfate d 100 100/10,000 59­1 10102­ Sodium Selenite d 100 100/10,000 18­8 10102­ Sodium Tellurite 500 500/10,000 20­2 10102­ Nitric Oxide b 10 100 43­9 10102­ Nitrogen Dioxide 10 100 44­0 10124­ Potassium Arsenite 1 500/10,000 50­2 10140­ Ethanol, 1,2­Dichloro­, Acetate 1,000 1,000 87­1 10210­ Cobalt Carbonyl d 10 10/10,000 68­1 10265­ Methamidophos 100 100/10,000 92­6 10294­ Boron Trichloride 500 500 34­5 10311­ Dialifor 100 100/10,000 84­9 10476­ Methacrolein Diacetate 1,000 1,000 95­6 12002­ Paris Green 1 500/10,000 03­8 12108­ Manganese, Tricarbonyl Methylcyclopentadienyl d 100 100 13­3 13071­ Terbufosh d 100 100 79­9 13171­ Phosphamidon 100 100 21­6 13194­ Ethoprophos 1,000 1,000 48­4 13410­ Sodium Selenate 100 100/10,000 01­0 13450­ Gallium Trichloride 500 500/10,000 90­3 13463­ Nickel Carbonyl 10 1 39­3 13463­ Iron, Pentacarbonyl­ 100 100 40­6 14167­ Salcomine 500 500/10,000 18­1 15271­ Bicyclo[2.2.1]Heptane­2­Carbonitrile, 5­Chloro­6­((((Methylamino)Carbonyl)Oxy)Imino)­, (1s­(1­ 500 500/10,000 41­7 alpha,2­beta,4­alpha,5­alpha,6E))­ 16752­ Methomyl d 100 500/10,000 77­5 17702­ Decaborane(14) 500 500/10,000 41­9 17702­ Formparanate 100 100/10,000 57­7 19287­ Diborane 100 100 45­7 19624­ Pentaborane 500 500 22­7 20830­ Digoxin d 10 10/10,000 75­5 20859­ Aluminum Phosphide a 100 500 73­8 21548­ Fosthietan 500 500 32­3 21609­ Leptophos 500 500/10,000 90­5 21908­ Mercuric Oxide 500 500/10,000 53­2 21923­ Chlorthiophos d 500 500 23­9 22224­ Fenamiphos 10 10/10,000 92­6 23135­ Oxamyl 100 100/10,000 22­0 23422­ Formetanate Hydrochloride d 100 500/10,000 53­9 23505­ Pirimifos­Ethyl 1,000 1,000 41­1 24017­ Triazofos 500 500 47­8 24934­ Chlormephos 500 500 91­6 26419­ Carbamic Acid, Methyl­, O­(((2,4­Dimethyl­1, 3­Dithiolan­2­yl)Methylene)Amino)­ 100 100/10,000 73­8

26628­ Sodium Azide (Na(N3)) a 1,000 500 22­8 27137­ Trichloro(Dichlorophenyl)Silane 500 500 85­5 28347­ Xylylene Dichloride 100 100/10,000 13­9 28772­ Bromadiolone 100 100/10,000 56­7 30674­ Methacryloyloxyethyl Isocyanateh 100 100 80­7 39196­ Thiofanox 100 100/10,000 18­4 50782­ Phosphonothioic Acid, Methyl­, S­(2­(Bis(1­Methylethyl)Amino)Ethyl) O­Ethyl Ester 100 100 69­9 53558­ Pyriminil d 100 100/10,000 25­1 58270­ Zinc, Dichloro(4,4­Dimethyl­5((((Methylamino) Carbonyl)Oxy)Imino)Pentanenitrile)­, (T­4)­ 100 100/10,000 08­9 62207­ Cobalt, ((2,2′­(1,2­Ethanediylbis (Nitrilomethylidyne)) Bis(6­Fluorophenolato)) (2­)­N,N′,O,O′)­ 100 100/10,000 76­5

*Only the statutory or final RQ is shown. For more information, see 40 CFR 355.61.

Notes:

a. This material is a reactive solid. The TPQ does not default to 10,000 pounds for non­powder, non­molten, non­ solution form.

b. The calculated TPQ changed after technical review as described in a technical support document for the final rule, April 22, 1987.

c. Chemicals added by final rule, April 22, 1987.

d. Revised TPQ based on new or re­evaluated toxicity data, April 22, 1987.

e. The TPQ was revised due to calculation error, April 22, 1987.

f. Chemicals on the original list that do not meet toxicity criteria but because of their acute lethality, high production volume and known risk are considered chemicals of concern (“Other chemicals”). (November 17, 1986, and February 15, 1990.)

g. The TPQ was recalculated (September 8, 2003) since it was mistakenly calculated in the April 22, 1987, final rule under the wrong assumption that this chemical is a reactive solid, when in fact it is a liquid. RQ for this chemical was adjusted on September 11, 2006.

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