DOCSLIB.ORG

French National Cancer Institute Scientific Report / 2015-2016 Scientific Report / 2015-2016

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
French National Cancer Institute Scientific Report / 2015-2016 Scientific Report / 2015-2016 OCTOBER 2016 For more information e-cancer.fr 2015-2016 / Institut National du Cancer 52, avenue André Morizet FRENCH NATIONAL 92100 Boulogne-Billancourt France REPORT SCIENTIFIC Tel. +33 (0) 1 41 10 50 00 CANCER INSTITUTE [email protected] SCIENTIFIC REPORT / 2015-2016 FRENCH NATIONAL CANCER INSTITUTE CANCER INSTITUTE FRENCH NATIONAL RAPCSANG16 FRENCH NATIONAL CANCER INSTITUTE FRENCH NATIONAL CANCER INSTITUTE SCIENTIFIC REPORT / 2015-2016 SCIENTIFIC REPORT / 2015-2016 The French National Cancer Institute is the health and science agency in charge of cancer control. Since 2003, the fight against cancer in France has been structured around national plans to mobilise all stakeholders on prevention, screening, care, research and support for patients and their friends and families. The 2003-2007 Cancer Control Plan set up the first comprehensive 52, avenue André Morizet strategy to fight cancer; the second Cancer Control Plan (2009-2013) introduced the notion of 92100 Boulogne-Billancourt personalised care. France The 2014-2019 Cancer Control Plan intends to give each and every person, all over France, the Tel. +33 (0) 1 41 10 50 00 same chances for recovery and implement innovation even faster for [email protected] Plan patient benefit. Cancer This plan includes 17 objectives, all gathered around four major 2014-2019 health priorities: l Cure more patients l Preserve continuity and quality of life l Invest in prevention and research l Optimise management and the organisations efficiency The Cancer Control Plan falls within the implementation of a national health strategy and the “France-Europe 2020” Strategic Agenda for research, technology transfer and innovation. All rights reserved. This work may not be translated or copied in whole or in part without the written permission of Institut National du Cancer. According to the Code of intellectual property, only copies strictly reserved for private use and not for a collective one, or brief excerpts justified by the scientific nature or information of the work into which they are incorporated, Published by the French National Cancer Institute are authorised. All rights reserved – Siren 185 512 777 Conception: INCa This document was published in October 2016. It is available at the following address: Realised by Institut National du Cancer (INCa) ISSN 2276-5751 Direction de la recherche ISBN : 978-2-37219-242-2 52, avenue André Morizet – 92100 Boulogne-Billancourt ISBN net : 978-2-37219-243-9 e-cancer.fr © 2016. Institut National du Cancer (INCa) DEPÔT LÉGAL OCTOBRE 2015 FRENCH NATIONAL CANCER INSTITUTE 3 2015-2016 SCIENTIFIC REPORT SCIENTIFIC REPORT 2015-2016 FRENCH NATIONAL CANCER INSTITUTE 4 2015-2016 SCIENTIFIC REPORT TABLE OF CONTENTS PREAMBLE 6 3. CLINICAL RESEARCH AND DEVELOPMENT OF EARLY‑PHASE TRIALS FOR INNOVATIVE DRUGS 56 Key figures 8 3.1. Clinical cancer research programmes 56 Clinical trials indicators 11 3.2. Early‑phase clinical trials for innovative drugs 59 Molecular genetics centres: activity indicators 12 3.3. Personalised medicine tools and programmes 62 International framework 14 3.4. Organisation of clinical research and strengthening of structures, infrastructures and tools 68 SUMMARY OF THE REPORT 17 4. RESEARCH IN HUMAN AND SOCIAL SCIENCES, Part 1. EPIDEMIOLOGY AND PUBLIC HEALTH 72 Summary of previous recommendations 4.1. The recurrent programme for Human and social of the members of the international Scientific Sciences (HSS), Epidemiology and Public Health (EPH) Advisory Board and corresponding achievements 19 Research 72 Part 2. 4.2. Population Health Intervention research 75 Report on 2015-2016 cancer research activity 29 4.3. Initiatives developed to support research on environmental risks 77 1. SUPPORT IN BIOLOGY AND BASIC SCIENCES 4.4. PhD Programme in HSS‑EPH 2016 in collaboration FOR CANCER RESEARCH 31 with academic partners 79 1.1. Research programmes 31 1.2. The genomic and the epigenomic programmes 40 5. INTERNATIONAL COMMITMENTS 81 5.1. Strategic vision, mission and values 81 2. TRANSLATIONAL AND INTEGRATED RESEARCH 45 5.2. INCa’s European commitments 82 2.1. Research programmes aiming to accelerate 5.3. INCa’s global commitments 84 cross‑disciplinarity and transfer of knowledge to clinical practice 45 6. BIBLIOMETRIC STUDY, EVALUATION AND REVIEW 2.2. The Translational and multisdisciplinary Research OF RESEARCH INVESTMENT 90 Training Programmes 50 6.1. Bibliometric study 90 2.3. Strengthening of organisation and infrastructures 6.2. Focus: Trends in the French funding stream dedicated to translational/integrated research of intervention research addressing all aspects in integrated cancer research sites (SIRICs) 54 of cancer control, a cross‑sectional analysis 2010‑2014 95 6.3. International evaluation 97 6.4. Review of research investments 98 FRENCH NATIONAL CANCER INSTITUTE 5 2015-2016 SCIENTIFIC REPORT Part 3. Conclusion 118 Focus on strategic topics for advancing cancer research 103 Appendices 119 1. CHALLENGES ASSOCIATED WITH THE ARRIVAL OF IMMUNOTHERAPIES 106 1. CLINICAL TRIALS REGISTRY 120 1.1. Biological and clinical databases: a unique tool to assess and monitor immune checkpoint inhibitors efficacy 106 2. CSO‑COMMON SCIENTIFIC OUTLINE 122 1.2. Resources and infrastructures integration to face the immunotherapy challenges 107 3. 2014‑2019 CANCER CONTROL PLAN ACTIONS PROGRESS RELATED TO CANCER RESEARCH 123 2. THE TRIPOD PROGRAMME: GENERATION, INTEGRATION AND SHARING OF BIOLOGICAL AND CLINICAL DATA WITHIN THE SCOPE OF PRECISION MEDICINE 109 2.1. Data collection and integration: development of decision‑making tools 109 2.2. Data sharing for coordinated targeted therapies assessment 110 3. STUDYING TO SET UP A SPECIFIC PROGRAMME SUPPORTING LATE‑PHASE CLINICAL TRIALS 111 3.1. Late clinical trials close to cancer care management to improve patients’ survival 111 3.2. Identifying the main challenges of current clinical practices 112 4. STRENGTHENING THE STRUCTURING OF CANCER PUBLIC HEALTH RESEARCH 113 4.1. Fostering the capabilities of human and social sciences, epidemiology and public health 113 4.2. Supporting the visibility of human and social sciences, epidemiology and public health research 113 5. NEW INTERNATIONAL COMMITMENTS 115 5.1. European initiative FLAG‑ERA on digital medicine for cancer 116 5.2. Joint Action on Rare Cancers 116 5.3. Global network on prostate cancer 117 FRENCH NATIONAL CANCER INSTITUTE 6 2015-2016 SCIENTIFIC REPORT PREAMBLE The 2015‑2016 scientific report, prepared by INCa in collaboration with Aviesan Cancer Institute (ITMO Cancer‑Aviesan), summarises the activities carried out this year in the field of research and innovation supported by the National cancer control plan (NCCP). We would like to take the opportunity to thank the Scientific Advisory Board’s (SAB) members for advising and guiding the Institute during its structuring process and providing relevant recommendations for its initiatives. The present report highlights the input of INCa and ITMO Cancer‑Aviesan during this 12‑month period to pursue the task of providing strong support in basic science research, translational research and training, clinical research, and research in the fields of human and social sciences, epidemiology and public health through the coordination of research programmes with its partners and the support of infrastructures and networks. The critical analysis of each programme is provided herein. This period’s focus has been on tobacco prevention, management of children with cancer and access to personalised medicine. Through all these different programmes, INCa has had an instrumental role on a European and international scale. The Cancer control plan intends to develop and roll out targeted therapies and personalised medicine and to strengthen the links between care and research, and transversely, places an emphasis on support and access to innovation for the treatment of malignant diseases. INCa coordinates personalised medicine programmes based on the patient’s tumour molecular profile, the PAOLA clinical trial including European centres based on BRCA status and the AcSé programme. The latter was described in Nature Reviews Clinical Oncology and the results of the two first AcSé programmes presented at ASCO 2016 meeting. Additionally, spin‑off results from INCa’s participation in the International Cancer Genome Consortium (ICGC) were achieved in 2016 with major results from two studies of the Breast Cancer Project, launched in 2008, published in Nature and Nature Communications showing how whole exome sequencing will further allow better tumour definition and disease classification. The role of coordination and support in cancer research of INCa and ITMO Cancer‑Aviesan cannot be achieved without providing strong parallel support whether at the funding or management level of structures and infrastructures. By way of example, the above achievements in personalised medicine and FRENCH NATIONAL CANCER INSTITUTE 7 2015-2016 SCIENTIFIC REPORT patient access to therapy could not be achieved without the molecular screening performed in the 28 molecular genetics centres throughout France, the collaborative clinical groups or the 16 early‑phase clinical trials centres (CLIP²) and the collaboration with its partners on a national and international level, in the academic or private sector. Multidisciplinary integrative cancer research is supported on a regional level by the Cancéropôles, Biological and clinical databases (BCBs) for specific tumours, and Integrated cancer research sites (SIRICs). In addition,
Load more

Recommended publications
  • The Closing of the Radical Right Gender Gap in France?
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by SPIRE - Sciences Po Institutional REpository Original Article The closing of the radical right gender gap in France? Nonna Mayer Centre d’études européennes de Sciences Po (CEESP), 28 rue des Saints-Pères, Paris 75007, France. Abstract One of the earliest and best-established finding about electoral support for populist radical right-wing parties is that they attract more men than women. Yet this finding might no longer apply to France. In the 2012, presidential election, contrary to her father, Marine Le Pen, the new leader of the Front National (FN), realized almost the same score among female and male voters. After controlling for other sociodemographic and attitudinal variables that explain electoral support for the FN, there is no difference between male and female voters’ support for the party. This article examines the closing of this gender gap in radical right-wing voting, drawing on post-electoral surveys con- ducted in 2002, 2012 and 2014. After a brief outline of the literature dealing with the emergence of the ‘Radical Right Gender Gap (RRGG)’, it ascertains the disappearance of a RRGG gender in 2012, tests possible explanations for this phenomenon and debates whether this is a temporary or a lasting one. French Politics (2015) 13, 391–414. doi:10.1057/fp.2015.18 Keywords: France; Front National; Marine Le Pen; gender; radical right gender gap One of the earliest and best-established findings about electoral support for populist radical right-wing parties1 is that they attract proportionately more men than women (Betz, 1994, p.
    [Show full text]
  • Policy Analysis in French Local Government Alain Faure, Emmanuel Négrier
    Policy analysis in French local government Alain Faure, Emmanuel Négrier To cite this version: Alain Faure, Emmanuel Négrier. Policy analysis in French local government. Charlotte Halpern; Patrick Hassenteufel; Philippe Zittoun. Policy Analysis in France, The Policy press, pp.119-135, 2017, 9781447324218. 10.1332/policypress/9781447324218.003.0007. halshs-01667336 HAL Id: halshs-01667336 https://halshs.archives-ouvertes.fr/halshs-01667336 Submitted on 3 Jan 2018 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. SEVEN Policy analysis in French local government Alain Faure and Emmanuel Négrier The subject of the present chapter attempts to ‘deconstruct’ the French territorial question and demonstrate that territorial policy analysis can break free from the limitations imposed by the primarily ‘statist’ conceptual framework in which it has hitherto been viewed. In the first section of the chapter, we indicate the scale and nature of the present political and administrative territorial structures and comment also on the paucity of academic research work on this subject. In the second section, we highlight the main changes in the territorial framework of policy building, through an evolution from vertical to horizontal dialectic of powers and capacities.
    [Show full text]
  • University of Oklahoma Graduate College Legacies of Empire: Greater France from Colonialism to Terrorism a Thesis Submitted To
    UNIVERSITY OF OKLAHOMA GRADUATE COLLEGE LEGACIES OF EMPIRE: GREATER FRANCE FROM COLONIALISM TO TERRORISM A THESIS SUBMITTED TO THE GRADUATE FACULTY in partial fulfillment of the requirements for the Degree of MASTER OF ARTS IN INTERNATIONAL STUDIES By MONICA GOODWIN Norman, Oklahoma 2016 LEGACIES OF EMPIRE: GREATER FRANCE FROM COLONIALISM TO TERRORISM A THESIS APPROVED FOR THE COLLEGE OF INTERNATIONAL STUDIES BY __________________________ Dr. Jessica Pearson-Patel, Chair __________________________ Dr. Emily Rook-Koepsel __________________________ Dr. Michael Winston © Copyright by MONICA GOODWIN 2016 All Rights Reserved. Table of Contents Abstract………………………………………………… v Introduction……………………………………………. 1 Chapter 1……………………………………………….. 8 Chapter 2……………………………………………….. 37 Chapter 3……………………………………………….. 57 Conclusion……………………………………………... 72 Bibliography……………………………………………. 73 iv Abstract Legacies of empire: Greater France from colonialism to terrorism Author: Monica Goodwin (University of Oklahoma 2016) In this thesis, I argue that the legacies of empire and colonization are influencing the development of French identity and are challenging notions of contemporary French society. I argue that these colonial legacies reached a watershed moment in 1989 with the headscarf affair and further provoked violent and socially divisive events such as the 2005 riots and the 2015 terrorist attacks. Furthermore, I argue that the effects of France’s colonial past have created a psychological empire that is negatively affecting many of France’s youths of immigrant
    [Show full text]
  • Military Service and Political Behavior: Evidence from France
    European Economic Review 122 (2020) 103364 Contents lists available at ScienceDirect European Economic Review journal homepage: www.elsevier.com/locate/euroecorev Military service and political behavior: Evidence from France ∗ Etienne Fize a,b, Charles Louis-Sidois a,c, a Sciences Po, Department of Economics, 28 rue des Saints-Pères, Paris 75007, France b French Council of Economic Analysis, 20 avenue de Ségur, Paris 75007, France c University of Mannheim, Collaborative Research Center 884 “Political Economy of Reforms”, B6, 30-32, Mannheim 68131, Germany a r t i c l e i n f o a b s t r a c t Article history: We investigate the impact of compulsory military service on turnout and political prefer- Received 17 December 2018 ences. Exploiting the suspension of mandatory conscription for French men, we observe a Accepted 12 December 2019 significant and positive impact of military service on turnout. We estimate that the service Available online 24 December 2019 increases turnout by approximately 7 percentage points. We also investigate the impact of conscription on political preferences. When we control for selection into the military JEL classification: D72 service, we observe no support for a change in preferences of former conscripts. F52 ©2019 Elsevier B.V. All rights reserved. Keywords: Voting Turnout Political behavior Military service 1. Introduction “[...] re-establishing a compulsory national service is absolutely necessary, not only to teach citizens how to adapt to the [terrorist] threat, but also to strengthen national cohesion.” Emmanuel Macron, April 18, 2017 A renewed interest in national services has been observed the past few years.
    [Show full text]
  • Productivity and Competitiveness: Where Does France Stand in the Euro Zone?
    July 2019 Report Productivity and competitiveness: where does France stand in the Euro zone? First report PRODUCTIVITY AND COMPETITIVENESS: WHERE DOES FRANCE STAND IN THE EURO ZONE? First report Chair Philippe Martin Members Agnès Bénassy-Quéré, Olivier Blanchard, Laurence Boone, Gilbert Cette, Chiara Criscuolo, Anne Epaulard, Sébastien Jean, Margaret Kyle, Xavier Ragot, Alexandra Roulet, David Thesmar JULY 2019 FOREWORD This first report by the National Productivity Board (NPB) seeks to present an overview, for France, of the key issues and questions concerning productivity and competitiveness. This is an original exercise that is set to evolve in step with the discussions with the social partners and other stakeholders, as well as with the other national productivity boards organised within a European network. The substantive work accomplished by rapporteurs – Vincent Aussilloux, Amandine Brun-Schammé, Flore Deschard, Margarita Lopez-Forero, Sébastien Turban (France Stratégie), Matthieu Jeanneney (Directorate-General of the Treasury), Matthieu Lequien (Banque de France), Fanny Mikol (Directorate for Research, Studies and Statistics/Dares) and Rémi Monin (National Institute of Statistics and Economic Studies/Insee) – has made a valuable contribution to this report, and I should like to extend sincere thanks to them on behalf of all the NPB for their dedication and professionalism. First and foremost, however, it is grounded in the joint deliberations of the Board members who played an active part in writing it. Harking from diverse backgrounds, these members are economists and researchers who are currently working or have previously worked in academic centres or international organisations and who share their views here completely independently of the economic and political authorities.
    [Show full text]
  • Is Islamic State in Retreat?
    Global Security Briefing – FEBRUARY 2015 IS ISLAMIC STATE IN RETREAT? Paul Rogers Summary This briefing looks at two unrelated incidents in the first weeks of 2015, in France and Syria, as indicative of major developments in the evolution of extreme Jihadist movements and that are likely to have long term effects. The Charlie Hebdo murders will lead to much more intensive counter-terror procedures in France and in greater security services cooperation across Europe but these also risk stimulating a further rise in the anti-Islamic mood. The execution of the young Jordanian pilot, Flight Lieutenant Moaz al-Kasasbeh by Islamic State (IS) in Syria looked initially to increase the resolve of regional states to confront IS. However, it is far from clear that recent suggestions that IS is more generally on the defensive are accurate. Charlie Hebdo On 7 January, two French brothers of Algerian descent, Saïd and Chérif Kouachi, entered the central Paris offices of the French satirical magazine Charlie Hebdo and opened fire on an editorial meeting, killing 12 people. In an apparently coordinated attack, hostages were later held at a Parisian kosher supermarket. Four customers and another police officer were killed by Amedy Coulibaly, an apparent associate of the Kouachi brothers. By the time the three attackers were killed in sieges on 9 January, France had deployed an estimated 80,000 police, army and other security personnel in response. Although Charlie Hebdo was a low circulation magazine, it was a part of French political culture and represented that strand, more prominent in France than in most European countries, of vigorous political lampooning, sometimes close to the obscene.
    [Show full text]
  • Overview of the French Operational Network for in Situ Observation of PM Chemical Composition and Sources in Urban Environments (CARA Program)
    atmosphere Article Overview of the French Operational Network for In Situ Observation of PM Chemical Composition and Sources in Urban Environments (CARA Program) Olivier Favez 1,2,* , Samuël Weber 3 , Jean-Eudes Petit 4 , Laurent Y. Alleman 2,5 , Alexandre Albinet 1,2 , Véronique Riffault 2,5 , Benjamin Chazeau 6,7 , Tanguy Amodeo 1,2, Dalia Salameh 3, Yunjiang Zhang 1,4, Deepchandra Srivastava 1 , Abdoulaye Samaké 3, Robin Aujay-Plouzeau 1,2, Arnaud Papin 1, Nicolas Bonnaire 4, Carole Boullanger 8,Mélodie Chatain 9, Florie Chevrier 10, Anaïs Detournay 11, Marta Dominik-Sègue 12, Raphaële Falhun 13,Céline Garbin 14,Véronique Ghersi 15, Guillaume Grignion 16, Gilles Levigoureux 17, Sabrina Pontet 18,Jérôme Rangognio 19, Shouwen Zhang 20, Jean-Luc Besombes 21 ,Sébastien Conil 22, Gaëlle Uzu 3 , Joël Savarino 3 , Nicolas Marchand 6, Valérie Gros 4, Caroline Marchand 1,2, Jean-Luc Jaffrezo 3 and Eva Leoz-Garziandia 1,2 1 Institut National De L’environnement Industriel et Des Risques (INERIS), Parc Technologique Alata BP2, 60550 Verneuil-en-Halatte, France; [email protected] (A.A.); [email protected] (T.A.); [email protected] (Y.Z.); [email protected] (D.S.); [email protected] (R.A.-P.); [email protected] (A.P.); [email protected] (C.M.); [email protected] (E.L.-G.) 2 Laboratoire Central de Surveillance de la Qualité de l’Air (LCSQA), 60550 Verneuil-en-Halatte, France; [email protected] (L.Y.A.); [email protected] (V.R.) 3 Institut des Géosciences de
    [Show full text]
  • Transition to Adulthood in France: Do Descendants of Immigrants Differ from Natives?
    50 (2016) Changing families and sustainable societies: Policy contexts and diversity over the life course and across generations Transition to adulthood in France: Do descendants of immigrants differ from natives? Giulia Ferrari and Ariane Pailhé © Copyright is held by the authors. A project funded by European Union's Seventh Framework Programme under grant agreement no. 320116 Transition to adulthood in France: Do descendants of immigrants differ from natives? Giulia Ferrari1 and Ariane Pailhé1 Abstract: This study examines whether major changes in patterns of transition to adulthood have taken place among descendants of immigrants in France. We simultaneously analyze the demographic events that make up the transition to adulthood for two main groups of immigrants’ descendants, i.e., North African and Southern European, and compare them to the pathway of native-born French. We identify five groups of similar trajectories using sequence and cluster analysis. In order to analyze how trajectories to adulthood are shaped by ethnic origin, gender, background characteristics and education, we estimate multinomial logistic regression on the likelihood of belonging to each of the five selected clusters. We find fairly similar paths to adulthood for descendants of immigrants and natives. However, specific patterns do emerge for immigrants’ descendants. They stay significantly longer in the parental home, partly because their parents come from societies characterized by strong family ties, and partly because they have greater difficulties becoming self-sufficient. Descendants of immigrants from North Africa, especially women, also have a lower probability of cohabiting. Finally, descendants of immigrants from North Africa behave more traditionally while descendants of immigrants from Southern Europe behave more like native French.
    [Show full text]
  • Cycle of Violence Countering Antisemitism and Extremism in France
    Breaking the Cycle of Violence Countering Antisemitism and Extremism in France January 2016 ON HUMAN RIGHTS, the United States must be a Acknowledgements beacon. Activists fighting for freedom around the globe We would like to give special thanks to The David Berg continue to look to us for inspiration and count on us for Foundation for their generous support. In addition, we support. Upholding human rights is not only a moral would like to thank Arthur & Toni Rembe Rock, the Alan obligation; it’s a vital national interest. America is B. Slifka Foundation, Robbie and Brad Karp, the Longhill strongest when our policies and actions match our Charitable Foundation, and the Tali and Boaz Weinstein values. Philanthropic Fund. Their combined support has made Human Rights First is an independent advocacy and the production of this report possible. action organization that challenges America to live up to This report is the result of research trips by Susan Corke, its ideals. We believe American leadership is essential in Floriane Hohenberg, and Rebecca Sheff to France during the struggle for human rights so we press the U.S. 2015 as well as interviews and consultations with a wide government and private companies to respect human range of human rights activists, government officials, rights and the rule of law. When they don’t, we step in to national and international NGOs, multinational bodies, demand reform, accountability, and justice. Around the scholars, attorneys, journalists, and victims. We salute world, we work where we can best harness American their courage and dedication, and give heartfelt thanks for influence to secure core freedoms.
    [Show full text]
  • Contrasted Epidemiological Patterns of West Nile Virus Lineages 1 and 2 Infections in France from 2015 to 2019
    pathogens Article Contrasted Epidemiological Patterns of West Nile Virus Lineages 1 and 2 Infections in France from 2015 to 2019 Cécile Beck 1,* , Isabelle Leparc Goffart 2,3, Florian Franke 4, Gaelle Gonzalez 1, Marine Dumarest 1, Steeve Lowenski 1, Yannick Blanchard 5, Pierrick Lucas 5, Xavier de Lamballerie 3, Gilda Grard 2,3, Guillaume André Durand 2,3 , Stéphan Zientara 1, 6 7 8 9, Jackie Tapprest , Grégory L’Ambert , Benoit Durand , Stéphanie Desvaux y 1, and Sylvie Lecollinet y 1 UMR 1161 Virology, ANSES, INRAE, ENVA, ANSES Animal Health Laboratory, EURL for Equine Diseases, 94704 Maisons-Alfort, France; [email protected] (G.G.); [email protected] (M.D.); [email protected] (S.L.); [email protected] (S.Z.); [email protected] (S.L.) 2 National Reference Laboratory for Arboviruses, Institut de Recherche Biomédicale des Armées, 13010 Marseille, France; isabelle.leparc-goff[email protected] (I.L.G.); [email protected] (G.G.); [email protected] (G.A.D.) 3 Unité des Virus Emergents (UVE: Aix Marseille Univ, IRD 190, INSERM 1207, IHU Méditerranée Infection), 13385 Marseille, France; [email protected] 4 Regional Office Paca-Corse, Santé Publique France, 13331 Marseille, France; [email protected] 5 ANSES Ploufragan-Plouzane-Niort, Viral Genetics and Biosecurity Unit, 22440 Ploufragan, France; [email protected] (Y.B.); [email protected] (P.L.) 6 ANSES Animal Health Laboratory, PhEED Unit, Dozulé site, F-14430 Goustranville, France; [email protected] 7 EID Méditerranée, 34184 Montpellier, France; [email protected] 8 Epidemiology Unit, Paris-Est University, ANSES Animal Health Laboratory, 94704 Maisons-Alfort, France; [email protected] 9 Office Français de la Biodiversité, Unité Sanitaire de la Faune, 01330 Birieux, France; [email protected] * Correspondence: [email protected]; Tel.: +33-143-96-73-34 These authors contributed equally to this work.
    [Show full text]
  • Report on Antisemitism in France
    Service de Protection de la Communauté Juive Jewish Community Security Service 2018 Report on Antisemitism in France Source of statistical data : Ministry of Interior and SPCJ This report can be downloaded in French and English at www.antisemitisme.fr This report was written with the support of the Fondation pour la Mémoire de la Shoah (FMS) The 2018 report on Antisemitism in France is dedicated to the memory of Mireille Knoll z”l, 85 years old, who was murdered on March 23, 2018 at her home. She was stabbed eleven times with a knife shouting "Allah akbar" and her body was found partly charred. At the age of 9, she had barely escaped the Vél’ d’Hiv Roundup. In memory of the 12 people killed in France since the early 2000s, because they were Jews. Sébastien Sellam Ilan Halimi (z’l) Jonathan Sandler Gabriel Sandler (z’l) (23)* (23) (z’l) (30) (z’l) (4) 2003 2006 2012 2012 Arié Sandler (z’l) Myriam Monsonego Yohan Cohen (z’l) Philippe Braham (5) (z’l) (7) (20) (z’l) (45) 2012 2012 2015 2015 François-Michel Yoav Hattab (z’l) Sarah Halimi (z’l) Mireille Knoll (z’l) Saada (z’l) (64) (21) (65) (85) 2015 2015 2017 2018 * Its Antisemitic nature was acknowledged by President Emmanuel Macron in May 2018. REPORT ON ANTISEMITISM IN FRANCE IN 2018 ANTISEMITISM IN FRANCE IN 2018 TABLE OF CONTENTS TABLE OF CONTENTS Table of contents 6 SPCJ 7 Eric de Rothschild SPCJ President 8 Our methodology 9 1. Assessment and analyses 10 1.1 Assessment and analyses 11 1.2 Recap chart of antisemitic acts recorded in 2018 13 1.3 Antisemitism In France In 2018 14 1.4 Antisemitic Acts recorded in France from 1998 to 2018 15 1.5 Racism and antisemitism in 2018 16 1.6 Geographic breakdown of antisemitic Acts in 2018 17 2.
    [Show full text]
  • What Goes Around Comes Around
    What goes around comes around A critical geopolitical analysis of contemporary western European terrorism as a process of tit-for-tat By Mark Nijland A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Human Geography with a specialization in Conflicts, Territories and Identities Under the supervision of Prof. Dr. Henk van Houtum July 2017 [II] What goes around comes around A critical geopolitical analysis of contemporary western European terrorism as a process of tit-for-tat Figure 1 with special thanks to Ruben L. Oppenheimer (2017) NRC Handelsblad Author: Mark Nijland Student number: s4220781 Contact: [email protected] Supervisor: Prof. dr. Henk van Houtum Second reader: Rodrigo Bueno Lacy, MSc Amount of words: 29.695 [III] [IV] ABSTRACT “France is at war”. These words, accompanied with a fierce military response, by then French president François Hollande heavily impacted western European counter-terrorism efforts. The response by France to the Paris attacks of November 13, 2015 paved the way for a Europe that engages in wars abroad in order to fight terrorism at home. This thesis analyses the extent to which contemporary western European terrorism could be perceived as a process of tit-for-tat. The dominant understanding of terrorism contains pervasive misrepresentations. Terrorist attacks are too often understood as isolated events that are happening only to states. Throughout this thesis, terrorism is understood as a process employed by both state and non-state actors. The ongoing and unsuccessful quest for a universally accepted definition of terrorism is exemplary for the complexity of the phenomenon.
    [Show full text]