The Safety of Influenza Vaccines in Children
Vaccine 33 (2015) F1–F67 Contents lists available at ScienceDirect Vaccine j ournal homepage: www.elsevier.com/locate/vaccine Review The safety of influenza vaccines in children: An Institute for Vaccine ଝ,ଝଝ Safety white paper a,b,∗ b,c d a Neal A. Halsey , Kawsar R. Talaat , Adena Greenbaum , Eric Mensah , a,b a,b a,b Matthew Z. Dudley , Tina Proveaux , Daniel A. Salmon a Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States b Institute for Vaccine Safety, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States c Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States d Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, MD, United States a r t i c l e i n f o a b s t r a c t Keywords: Most influenza vaccines are generally safe, but influenza vaccines can cause rare serious adverse events. Influenza Some adverse events, such as fever and febrile seizures, are more common in children than adults. There Influenza vaccine can be differences in the safety of vaccines in different populations due to underlying differences in Vaccine safety genetic predisposition to the adverse event. Live attenuated vaccines have not been studied adequately Local reactions following IIV in children under 2 years of age to determine the risks of adverse events; more studies are needed to Cellulitis-like reactions address this and several other priority safety issues with all influenza vaccines in children.
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