2017IMPACT REPORT 2 “Life changes in the instant. The ordinary instant.” JOAN DIDION

For me, “that ordinary instant” happened in 2006 oral antibiotic (minocycline) can greatly reduce the risk of early disease when my son, then 23, was diagnosed with multiple sclerosis. progression in MS. This was an incredible discovery coming from the Nothing in our family background prepared us for this, and our labs of Drs. Wee Yong and Luanne Metz, and we hope to see more only experience with MS had been through a dear friend who was real-world research impacts like this one in 2018. Another notable diagnosed at 45 with primary-progressive MS. Fortunately, my collaboration is our partnership with Biogen Canada and Brain Canada son’s experience has been very different from our friend’s, which to launch a multi-year cohort study to investigate key questions about was tragic. Back then, there was little hope, and today there is a disease progression, like why do some people develop secondary great deal. progressive MS and others do not? Through the lens of an incurable and unpredictable disease, The beginning of 2018 marked a significant milestone in MS treatments. not knowing what the future holds is frightening. The MS Health Canada approved Ocrevus, the first disease-modifying therapy Society of Canada aims to give people hope for a better for people living with primary-progressive MS. Ocrevus is a step tomorrow, fueled by information and knowledge that forward in treatment options; however, we know one treatment does helps people make the decisions that are right for them. not work for everyone, so while we celebrate this breakthrough, we We are working tirelessly to ensure movement in know we have more work to do. progressive MS research, to provide greater support The last 18 months have been full of change, challenges, celebrations and information to Canadians impacted by MS, and and progress. Sylvia Leonard stepped into the role of interim president to address the questions that remain unanswered. and CEO in March, and under her steadfast leadership, we maintained I am happy to report to you that our MS momentum on our organizational priorities. I thank Sylvia for her Knowledge Network completed its first full dedication and guidance. Her contributions will not be forgotten and year of operation and served more than 2,600 we wish her well on her retirement. members of our community through email, It is my privilege on behalf of the Board of Directors to introduce the phone, social media and our new live chat MS Society of Canada’s new president and CEO Dr. Pamela (Pam) web feature. Our 1:1 Peer Support Program, Valentine. Pam obtained her PhD in neuroscience and has a strong Volunteer Legal Advocacy and Friendly record in research collaboration, ingenuity and inspirational leadership. Visiting programs will all be expanded this We are thrilled to have Pam leading us through this era of innovation. year, increasing our impact locally and With immense gratitude, I thank our donors who have invested in further empowering members of our changing the lives of Canadians living with MS. Without you, it would be community. impossible to envision a future free of MS. MS research continues to build momentum in Canada and abroad. This past year one of our funded studies yielded impressive results, Valerie Hussey, C.M. showcasing how an affordable Chair, Board of Directors, MS Society of Canada 3 Improve #LifeWithMS

Every day, we are working towards our mission to improve the 80+ ADVOCACY MEETINGS quality of life for those affected by multiple sclerosis and to ultimately find a cure. with MPs, senators and senior Whether it’s through fundraising, programs and services, advocacy, research or development, we are inspired by your stories and the day-to-day experiences of level staff in Ottawa people affected by MS. The unpredictable effects of MS are physical, emotional, financial and can last forever. MS impacts all Canadians – not only the individuals living with the disease, but also their friends, families, workplaces and healthcare teams – who all come together to manage the realities of MS.

Since 1948 we’ve provided more than $175 million towards funding for MS research and researchers in Canada thanks to your donations and fundraising efforts. 58,000+ social media Canada has one of the highest rates of MS, but we are also home to some of the world’s leading researchers – what better place to come together as Canadians followers engaging with us and continue our fight against this unpredictable, chronic disease?

You are a part of this momentum and we are grateful for your efforts. Without your donations and without your voice, we cannot Gain insight into living with MS and find effect change for Canadians out how you can help urge our living with MS. Know that governments to support people when you share your desire affected by the disease at for a future free of MS, you blog.mssociety.ca. are making an impact. Use the hashtags #LifeWithMS and #ThisIsMS to add your voice to the Lelainia uses art to help manage her MS. Mural by Steve and Sandy Pell. community. 4 Tackling the Biggest MS Challenge

MAKING PROGRESS FOR PROGRESSIVE MS COLLABORATIVE GLOBAL EFFORT TO END PROGRESSIVE MS This year, we reached an important milestone with the conditional approval of Ocrevus by Health Canada for the treatment of adults For the first time, people with progressive with early primary-progressive multiple sclerosis (PPMS). forms of MS are at the heart of a global effort to stop MS in its tracks. Progressive MS is the “Over the years we have seen many new treatments come to most confounding issue facing MS researchers market that manage relapsing-remitting MS, but there have today. The Canadian research community and been no disease-modifying therapies for people living with our global partners are working together to find “If we can stop progressive MS,” says Dr. Karen Lee, vice-president, research, answers. MS Society of Canada. “The approval of Ocrevus is a much- MS in its tracks, needed treatment because, for some people living with The International Progressive MS Alliance (the then no one has PPMS, Ocrevus may help control and even slow disease Alliance) is a growing multi-organizational group progression. Hopefully, this is the beginning of many more that brings together the world’s leading experts to fear disease treatment options for people living with PPMS.” to put an end to progressive MS. As one of progression the founding and managing members of the “I feel even more hopeful about the advancements Alliance, the MS Society has contributed over ever again.” being made in MS research – especially ones showing $2 million, thanks to donor support. The Alliance positive results in terms of having the potential to help aims to identify the critical knowledge and CORY TURNER, treat progressive MS,” says Cory Turner, director, treatment gaps where advances must be made DIAGNOSED MS Scientific Research Foundation, member, to achieve breakthroughs necessary to change IN 2005 Medical Advisory Committee. “If we can stop the world for people with progressive MS. MS in its tracks, then no one has to fear disease progression ever again.” THE ALLIANCE HAS FOUR PRIORITIES:

Better understanding Designing shorter, faster progression to identify trials that measure patient and test treatments outcomes

Conducting trials to test Developing and potential therapies evaluating new therapies to manage symptoms 5 Funding the Best New Research in Canada The complexity of progressive multiple sclerosis is one of the greatest barriers facing Canadian researchers today. With the significant support of donors and partners, the MS Society of Canada funds a network of brilliant minds focused on solving progressive MS.

Dr. Christopher Power RESEARCH FOCUS: INFLAMMATORY MEDIATORS OF PROGRESSIVE MS Structures located in the brain, called Dr. Craig Moore inflammasomes, are made up of many Memorial University of Newfoundland different proteins that, when bundled RESEARCH FOCUS: PROTEINS together, activate the brain’s immune Dr. Shannon Kolind REGULATING REPAIR IN PROGRESSIVE MS response. Preliminary work from University of British Columbia Dr. Craig Moore is working to identify a Dr. Christopher Power’s laboratory RESEARCH FOCUS: INDICATORS OF suggests that inflammasomes may fuel DISEASE PROGRESSION IN MS novel target that could be further explored for treating both relapsing and progressive the autoimmune attack in primary- Dr. Shannon Kolind’s study aims to identify forms of MS. He and his team are studying progressive MS. Dr. Power and his team individuals at risk for severe progression by specific molecules called microRNAs, which are investigating how inflammasomes focusing on establishing an imaging biomarker are potential new targets for progressive MS affect brain anatomy and function in that efficiently tracks changes in progression treatment. Found in both brain and immune primary-progressive MS (PPMS), while in individuals living with MS. Biomarkers are cells, microRNAs play an important role in exploring what molecules are responsible biological clues from the body that can tell us controlling inflammation and tissue repair in for inflammasome activation in human about the state of a disease or the effect of a the damaged brain. The Moore lab discovered brain cells. Their findings will shed light treatment. Dr. Kolind’s research team wants one microRNA molecule (microRNA-223) in on the role of the immune system in to explore the loss of myelin (the protective particular to be important in promoting repair PPMS and potentially lay the groundwork sheath around certain nerve fibres that is in MS. Ongoing studies are investigating the for the development of biomarkers and damaged in individuals living with MS) as a role of this molecule in animal models of MS. treatments for MS. potential biomarker. Her study could lead to the reduction in cost and time required for progressive MS clinical trials and help with treatment decisions. 6 Research Milestones in Multiple Sclerosis MS Society of Canada and MS Scientific Research Foundation

1949-1989 1990–1999 2000–2004 2005–2009 2010–2011

1949: MS Society of 1993: MS Scientific 2000: MSSRF funds $4M Canadian Bone Marrow 2008: Dr. Paolo Zamboni 2010: $2.4M joint funding Canada (MSSC) awards Research Foundation Transplantation (BMT) trial—aims to determine identifies a possible from MSSC and National first grant to Dr. Roy (MSSRF*) funds its whether wiping the immune system and transplanting association between MS Society to fund seven Swank for diet research. first research grant for bone marrow stem cells can treat MS and provide chronic cerebrospinal critical studies into the 1981: First magnetic $2.2M for the Canadian clues into its cause. venous insufficiency connection between resonance imaging Collaborative Project on 2001: McDonald Criteria for diagnosing MS (CCSVI) and MS. CCSVI and MS. (MRI) pictures of an Genetic Susceptibility to established—first diagnostic criteria to incorporate MSSC and MSSRF launch 2011: MSSRF funds $3.8M MS-affected brain MS (CCPGSMS). Funding both clinical and imaging measures. $20M endMS Research multi-center study provided for additional revolutionize diagnosis. 2003: As part of the CCPGSMS supported by the and Training Network, focused on progressive project phases over the a comprehensive multi- forms of MS. next two decades. MSSRF, the largest population-based MS DNA bank, including information on people living with MS and platform initiative CPDDN identifies 1995: First disease- their biological relatives, is established. designed to attract, key MRI patterns in modifying therapy (DMT) train, and retain the children with MS. The for relapsing-remitting 2004: Link between higher vitamin D intake and next generation of MS reduced MS risk identified. discovery that pediatric MS (RRMS) approved in researchers. MS affects memory Canada (Betaseron). MSSC and MSSRF fund $4.3M multi-centre study MSSC hosts first endMS and learning allows for 1996: First evidence of children who have had an initial demyelinating Conference—largest more timely access to published that exercise attack. The Canadian Pediatric Demyelinating Disease conference in Canada treatment and care. improves quality of life Network (CPDDN) is one of the largest and most aimed at fostering with MS. comprehensive pediatric MS cohorts in the world. knowledge exchange on MS-related research, networking, and collaboration. 1996-2017: 13 additional DMTs approved by Health Canada for RRMS.

*The MSSRF is an affiliate of the MS Society that was established to support innovative MS research that extends beyond the scope of the MS Society’s regular granting program. 7

2012-2014 2015 2016 2017 2018

2012: Launch of CPDDN receives $3.2M Launch of the Updated McDonald Criteria for diagnosis of MS. The Ocrevus (ocrelizumab) International Progressive from the MSSRF to Hermès Canada | revisions lessen the risk of misdiagnosis and allow for earlier conditionally MS Alliance, a group of continue to lead pediatric MS Society Wellness diagnosis of MS. approved by Health organizations committed MS research efforts Research Innovation $7+M call for proposals announced by MSSC, Biogen Canada as the first to accelerating the focusing on quality of Grant, funding Canada and Brain Canada inviting researchers to establish disease-modifying development of life, health care service aimed at translating the first Canadian cohort of people living with MS to study therapy available treatments and resources utilization, brain research findings disease progression. for early primary- for progressive MS. development, cognitive progressive MS. into innovative Minocycline clinical trial demonstrates delay in MS onset in MSSC is a founding performance and the wellness solutions member. immune system. people with early signs of the disease who received this safe to improve health and inexpensive acne treatment. An example of bench to 2014: MSSC and MSSRF MSSRF funds $4.2M and quality of life for bedside research, this $4M trial funded by the MSSRF built fund $3.6M to understand MEsenchymal Stem cell people affected by on previous work, supported by MSSC. the role of the B cell in therapy for CAnadian MS. the development and MS patients (MESCAMS) Preliminary analyses of Pan-Canadian Interventional Clinical Canadian BMT Trial Trial for CCSVI in MS (funded by the MSSC, Canadian progression of MS. clinical trial. MESCAMS results published— is part of an international Institutes of Health Research, Provinces of British Columbia, shows no new Manitoba and Quebec), show no statistical difference in mesenchymal stem cell disease activity research effort outcomes between those who received the procedure and following treatment those who received a sham procedure (placebo). encompassing nine in patients with countries. Unlike previous aggressive, highly- stem cell studies, inflammatory RRMS. Thanks chemotherapy is not required here. $175M to You Overall investment from Many of these advances MS Society of Canada and would not have been MS Scientific Research possible without the Foundation to research. generous support of our donors. 8 Empowering People to Live

We heard from Canadians living with multiple sclerosis HERE FOR YOU Sometimes when newly diagnosed, or when searching that navigating their MS journey was one of the most for answers about a new challenge, the best person to turn to is someone challenging aspects in their day-to-day lives – particularly who has similar experiences. After two years of service, the 1:1 Peer with the inaccurate and limitless amounts of MS information Support Program has had a dramatic effect in reducing social isolation available, and the complexities of the healthcare system. The and loneliness. The confidential support program matches individuals MS Knowledge Network launched in 2016 as a hub of navigators living with MS with volunteers who have lived similar experiences. No providing reliable, high-quality MS information and support matter where you live in Canada and where you are at in your MS for Canadians. Via phone, email and live chat, MS Navigators journey, knowing you can turn to someone who has lived a shared provide trusted information on different aspects of life with MS experience can make living with MS easier. tailored to the unique needs of each individual, including symptom ~ 2017 HIGHLIGHTS ~ management, drug/medications, peer support, access to professional health services, income support, current research and navigating community resources.

45 active trained volunteers 99 of 143 matches made ~ 2017 HIGHLIGHTS ~ living with MS providing since the launch of the guidance to peers program Served over 2,600 people affected by MS and answered Launched live Initiated services Provided support through over 4,200 web chat on to French-speaking multiple channels inquiries mssociety.ca Canadians including social media 80% said they would 80% of peers agreed or recommend the program strongly agreed that they to someone else affected were very satisfied with the 89% of people were satisfied with their by MS 1:1 Peer Support Program Based on feedback experience connecting with a Navigator and we’ve received 85% would recommend the service to someone else affected by MS. “Peer Support made a difference in how I am managing my illness. My outlook has improved and I made a friend in the We are grateful to the RBC Foundation for their process. Thank you.” significant support of the MS Knowledge Network. 1:1 PEER SUPPORT PARTICIPANT 9 Working Together for Change

Reducing barriers for people living with multiple sclerosis is paramount to enabling them to live full, productive lives. In partnership with people living with MS, we advocate for changes in three critical areas: In total, 5,048 letters MAKE WORK, WORK by making employment supports in English and The MS Society of Canada descended and programs more flexible and inclusive – to allow French were on Parliament Hill during MS people with MS and other episodic disabilities to remain submitted to MPs in the workforce. Awareness Month to raise awareness that Canada has one of the highest rates of MS in the world and to ask MAKE ENDS MEET by improving income and disability the government to take action to supports for people with MS who are unable to work or improve #LifeWithMS. We had over can only work on an intermittent basis. 80 meetings with parliamentarians and hosted our annual carnation pinning.

MAKE ACCESS A REALITY by implementing federal During the fall of 2017, we launched the We connected accessibility legislation, increasing access to treatments online advocacy campaign Act Now to with 332 and investing in comprehensive home care. Improve #LifeWithMS. This campaign constituencies encouraged community members to take action by sending messages to their MPs asking them to support From left to right: Benjamin Davis (MS Society); Marilyn Lenzen (volunteer); The Right Honourable Justin Trudeau, Prime Minister of Canada; Rahil Dattu (Board critical steps to improve #LifeWithMS. member, volunteer); The Honourable Hedy Fry (Member of Parliament).

MPs heard you! The average number of letters each MP received was 15 10 The Power of Collective Action

Christine Sinclair is a true national treasure. She led our Canadian women’s soccer team to win back-to- back Olympic medals, and in 2017, she led Canada in the fight against multiple sclerosis as the face of our A&W Burgers to Beat MS campaign.

This is personal for Christine. Her mother was once an athletic soccer mom, coach and also her daughter’s biggest cheerleader. Things have changed since she’s been diagnosed with MS. Now, the only time she sees Christine is within the walls of her long-term care facility.

“It’s difficult to watch someone you love have to deal with such a debilitating disease,” said Christine. “Using my voice for something like this is completely new to me, but I see the impact we’re making and it’s a great feeling.”

In 2017, the collective power of 900 A&W restaurants and their communities across the country raised a record-breaking $1.85 million, bringing the partnership’s nine-year total to $11 million. From rounding up bills, to donation mugs, to $2 donated from every Teen Burger® sold on August 24, the A&W family made an incredible impact in the lives of Canadians living with MS.

Thank you to all our community partners. We couldn’t make an impact without you! 11 Making a Difference in Women’s Health

In Canada, women are three times more likely to be diagnosed with I CHALLENGE MS is a program that strengthens multiple sclerosis than men. That’s one reason we are excited to partner people’s fundraising efforts by providing flexibility and with Shoppers Drug Mart. With the Shoppers LOVE. YOU. initiative, key resources to support individual, group or corporate our newest corporate partner is putting women’s health first. challenges. From bake sales, to birthday dinners, to cycling across the country, hundreds of Canadians use This partnership will establish Shoppers Drug Mart as a corporate and community leader in supporting Canadians with MS through their passion to raise money and awareness, often because awareness, education and partnering with pharmacists who are a of a personal connection to MS. vital part of the MS health care team. Shoppers LOVE. YOU. will also be the presenting sponsor of the Women Against MS Gala BE ACTIVE Former AHL in Toronto, an event that honours women who make an impact star Darren Haydar in the business community and raises more than $350,000 KUDOS TO EVERYONE annually. hosted a golf event and WHO PARTICPATED IN A raised $40,000! CHALLENGE IN 2017.

“As a pharmacist and woman who has MS, I understand how BE AN essential it is for people with INDIVIDUAL MS to have positive interactions Stephanie is a fearless with their pharmacists. Things hairstylist who raised $1,500 like education and everyday by shaving her accessibility can be so head!

important.”

JULIE JEAN, SHOPPERS DRUG MART PHARMACIST Visit www.ichallengems.ca for more information. 12 Campaign donors

Thanks to our donors, Canada is leading the world closer to new breakthroughs and treatments for multiple sclerosis. Our network of brilliant minds relentlessly studies every aspect of the disease, from its root causes to comprehensive disease progression. These advances are not possible without significant investment from our donors. The MS Society of Canada is grateful to the following donors who have made a generous commitment to the endMS: Whatever It Takes campaign.

$1 MILLION + In Honour of Bill & Isabel Kelley Portage la Prairie Century 21 Foxx* Bennett Jones LLP Kent Kirkpatrick Lori Radke Biogen Canada Jack Cohen Family Foundation* Kerri Riddle Jon and Nancy Love Foundation at Doug McGregor* Scott Builders Inc.* Toronto Foundation Pacific Blue Cross Community Connection Health Bruce Shultz* PCL Constructors Canada Inc. Foundation Edward Shwedyk The Waugh Family Foundation Pratt & Whitney TD Securities* RBC* RBC Foundation Cathy Topping* ShawCor Pipe Protection LLC* Marie Vaillant $500,000-$999,999 SMash Out MS Charity Golf Tournament Yaffe Feld Fund in loving memory of John Feld* Osler, Hoskin & Harcourt LLP* The Lawrason Foundation* * Made a commitment in 2017 Anonymous (2) Reno Trentini $100,000-$499,999 Triumph Tool Ltd. and Duffy Family Chorus Aviation Cory Turner Thank you to our dedicated volunteers Bob & Pat Decker Gary Ursell & Helen Kearns* Donald Berman Foundation Patrice Walch Watson who are helping to end MS. Marvin, Myrna & Jason Guenter* $1,000-$9,999 Hermès Gary B. Altenkirk* Valerie Hussey, C.M. Jennifer Beqaj Fred Moore Butler Family Foundation Rhonda Peterson CBRE Ltd. Joseph Randell John Clifford Scotiabank Salvatore N. & Charlene Corea The Paul and Margy Campbell Family Foundation Phil Dewan* David L. Torrey Enterprise Rent-A-Car on Waverley* Anonymous Dr. Thomas Feasby, C.M.* $10,000-$99,999 Bonnie & Stacey Gleim* AGF Management Limited Suzanne Gouin Gayelene Bonenfant Dr. Mark Heule & Mrs. Nancy Heule* Flames Foundation* Investors Group Sidney Cohen, in memory of Ruth Cohen* Peter Jelley Dyer Family Fund in Support of the International Kleinfelder Canada Inc.* Progressive MS Alliance* Brian Kusisto EVRAZ North America* Daniel Larouche Fillmore Construction Murray Lukawitz Chuck Ford Malouf Family Fund Friends of Asad Wali Fund Maxwell Cummings Family Foundation G&F Financial Modico Parking Inc. Gateway Tubulars Ltd.* Catherine Murray Boris* Adam Grosjean Phillip Harahus Charitable Gift Fund* 13 leadership donors Dr. Jiwon Oh, neurologist, The MS Society of Canada is pleased to thank and recognize our tremendous community of St. Michael’s individuals, foundations and corporations from across the country who made a leadership gift in Hospital. 2017 in support of our mission and those living with multiple sclerosis.

$250,000+ $10,000-$24,999 Estate of Robert Arnold Alice & Murray Maitland Foundation $100,000-$249,999 All Charities Campaign Estate of Pierre Astel Late Magnus Bayne Estate of James Craig Bremner Estate of Lucille Loiselle Girard Estate of Edna Cahill Estate of Elizabeth Robertson Haynes Estate of Elizabeth Milne Estate of Myrna Castellaro Anonymous Crist Family Foundation Estate of Lyse David Estate of James Shea $50,000-$99,999 Estate of Denis Desjardins The Calgary Foundation Estate of Doreen Barker Leblanc Estate of Mary Dickinson Joanne Tosini Estate of Claire Gordon Firth Estate of Odette Duval VOCM Cares Foundation Estate of Doris Hyde Estate of Evelyn Elizabeth Edwards Estate of Margaret Ethel Wallace Kin Canada District 7 Atlantic Douglas Ellenor WCPD Foundation Lank Family Fund Agnes Faraci* Estate of Dorothy Wright Estate of Helen Gertrude McIntosh Fleming Foundation Anonymous Estate of Norman McMillan Fondation Bergeron-Jetté Estate of Kirk Roland Morgan Fondation Richelieu Montréal $5,000-$9,999 Estate of Yolande Oligny Freedom International Brokerage Company Estate of Helene Bocsanczi Estate of Brian Strawbridge Government of Canada (HRSDC) Bourassa Savaria Foundation Estate of Marilyn Swanson Estate of Mary Heipel Estate of Bernard Bourgeois The Law Foundation of BC Paul Hollands CN Employee’s and Pensioners’ Community Fund Vancouver Foundation Hydro-Québec Robyn Cohen Anonymous Colin & Jo Jackson* Ron Couvrette* $25,000-$49,999 R. Jackson* Late Edith Crowston Estate of Eleanore Ard Crawforth Joseph & Helen Mykietiuk Fund James Ehrensperger Estate of Beverly Ann Barnes Leon’s Furniture Mary Ann Everest Estate of Gladys Irene Cadieux Diane Loeb George Fine* Estate of William Henry Cameron Estate of Lois Irene Miller Dr. Michael Fiorino* Crane Fund for Widows and Children Estate of Germain Morel Fondation André Gauthier Estate of Elsie Rosemary Diamond NorthWest Healthcare Properties Fredericton Community Foundation Estate of Maud Duncan Curtis NWM Private Giving Foundation Gopher Enterprises Limited* Estate of Eleanor Isabel George Oak Bridge Holdings Inc. HME Mobility & Accessibility Estate of Virginia Ruth Griffin Peter O’Sullivan J. Richard Armstrong Family Foundation* Estate of Ruth Harwood Jason & Marie-Claude Park Jeunesse-Vie Foundation In Honour of Bill & Isabel Kelley RBC Foundation John Arthur Clark Family Testamentary Trust Margaret Roche-Heywood Foundation Roy Robbins John Deere Foundation of Canada Estate of Marjorie Mortlock May W. Michael Roche Gale M. Kelly The Catherine and Maxwell Meighen Foundation Estate of Evelyn Rymer Pierre Lajoie* Anonymous Sanofi Genzyme Daniel Larouche* 14 Robert Leon Veron Consultants Inc. Bison Transport Del Chinnick* Denis Loiselle Florence Wall Marjorie Blankstein C.M., O.M.* May Lena Chiu* Brent MacIntosh* Maurice Walsh* Gloria Block* Marguerite Choquette* Thomas G. Melanson* Wellington West Foundation Jeffrey Block* Christopherson Foundation Murray Meltzer Thomas Whitfield * John Bobenic* C. Churchill* Patrick & Michele Meneley Anonymous (2) Robert Boettger* Clark Builders Henry S. Mews* Thérèse Boileau* Edna Claydon* $1,000-$4,999 Estate of Sheila Gladys Morgan Jeanne Boire* Barrie W. Clayton* 414 Union Street* Mary Lee Mowatt Will Borsa* Marius Cloutier* 767269 Ontario Limited* Mr. & Mrs. L. Murray* Giuseppe Borsellino Cloverdale Paint Inc. Claire Adam* Alanne O’Gallagher* Susan Bose* Brent Cochrane* Agway Metals Inc.* John & Ann Ogilvy* Derek Bradley* Pierre Coiteux* Lorne A. Peters James E. Allard* Jocelyn Braithwaite* Stephen Coldwell* Estate of Zonia Piskun Val Allardice* Catherine Bratty* Dori Coleman* Estate of Clare Rose Lyall & Lois Allison* Dean Brayer* Jessica Collis* Estate of Allison Duncan Rosenberg John Allison* Donald Brazier* Collombin Family Fund at Scott Builders Inc. Allô! Mon Coco 2700 boul. Laurier James A. Brierley* Toronto Foundation Owen Bruce Shime* #0508* Broadview Capital Management Inc. Jim Colvin Shorcan Brokers Limited Fran Allwood* Ginette Brochu Jean Comfort* H. Simpson* Alpha Rho Master - MA 1293 Estate of Florence Bourbonnais Rosemary Congdon* J. Snyder* David Andermatt* Phyllis Beverley Brown* Paul Coopman* Joe Spagnolo* Clifford Anderson* BSD Solutions Ltd.* June Copley Estate of Helen Allen Stacey William Anglin Estate of Shannon Kim Budinski Gérard Cormier* The Brent MacIntosh Real Estate Group* Patricia Armstrong* Richard Buggelin* Colin & Merl Cory The Gauthier Family Charitable James Armstrong* Michael Bulger* Jean Pierre H. Cote* Foundation Amy Arnold* Stephanie Burgoyne* Denis Cotnoir* Jonathan Toll Irene Askew* Craig Burkart* Paule Couet* John Torrey* Wm Aspden* Estate of Eric Burton Raymond Coulombe* Frederick J. Troop* ATCO Gas Butler Family Foundation Charles Courchesne* ATCO Pipelines Howard Bye* Riki & James Cox* ATU Jerry Fund Calgary Juventus Sports Club Casion Suzanne Crawford Audrey Jackson Fund Account* Alice J. Crawford* Harold Baardsnes* Maureen Campbell* Cremona & District Community Chest Hans-Heinrich Baeggli* Canada Life Crescent Lodge 81 John Baillie* Canadian Federation of Agriculture* Crestview Investment Corporation* In Memory of Joel Balfour* Alvin Carberry* Gail Crockett* Rudy Bandsmer* Suzanne Caron* Bob Cronin Barber Motors* Kelly & Sarah Carrick* Robin Cruickshank* Judy Bargholz* Carte International Murray & Lois Cummings* Earl & Cheryl Barish* Castor & District Community Chest Barbara Currie* Karen & Bill Barnett* Laurie Cavanaugh Kathleen Curtis* Leonard Bartlett* Central Okanagan Foundation Richard Cusson* Virginio Basile* Challenger Motor Freight Inc. Brian Cuzner* Larry & Nancy Behnsen* Jack MacDuff Claude Chamberland Marcelle Dagenais* Kathy Bell* Carlos & May Chan* Ron & Elise Dalby* lives with MS, Gilles Benoit* Chancery Pacific Trade Corporation Estate of Louise Dallaire fundraiser for Cathy Bertini* Roy & Nancy Chen* Firoz Dattu* Jean-Noël Bérubé* Nancy Cheung* Lois Davis MS Walk and MS Bill & Helen Davidson Foundation Paul Chevalier* Grace & Glenn Davis* Bike. Bruce & Jo Bird* Greg Child* Bernard De Serres* 15 Peter Demik* Susan Fisher* H.J. Stultz Family Foundation* Dr. Luanne Metz, professor and head Suzanne Deschênes* Gordon Flann* Michael Hafeman* Ronald Desrochers* Claude Foisy* Maureen Hall* of neurology, . E. Dessouki* Fondation Denise et Robert Gibelleau Ingrid Hall* Estate of Marguerite Désy Brad Forden & Carole Fujimoto* Terry Halpin* Di Poce Management Limited* Form & Build Management Inc.* Keith Harper* Peter & Anna DiGiuseppe* Henry Forrieter* James Harris* Caroline Dillon Nicol* Fort MacLeod Fire Department Haskett Growers Ltd. Luigi Di Marzo & Charlotte Moran* Patricia Fortier* Ruth Hastings* Mariette Dion* Lisa Foster* Marilyn Heddle* Dione Appleton Investments* Derek Fox* Wanda Hemsworth* Estate of Norma Audrey Dobbin David Foxe* Eileen Herdman* Walter Dobrovolsky* Allan Fraser* Dr. Mark K. Heule* Docteur Yvan Salvetti Inc.* Fraternal Order of Eagles - North West Aerie Thomas Hicks* Domtar Electric Shop Copper Fund* #2638 Dave Hill Donburg Farm Limited* Fred North Charitable Foundation In Memory of Graham Hill Ian Donnelly Annie Freeze E. Hilton* Doris Duchesne* Norbert Frischkorn* Greg Hogge* Louis Dufresne* Harvey Fruitman Muriel Hole* John J. Dugan Funds Administrative Service Inc.* Michael Holland* Dave Kelly* Paul & Janet Dullaert* Carol Furlong* George Holland* Cheryl Kendall* Paul Dullaert Fusco Family Charitable Trust* Alan Holt* Audrey Kenny* John Dungey* Tania Gallant* Greg Honey* Dorothy Kerr* Randall Dutka* Gertrud Gambhir* Norman Hopland* John King* Estate of Shirley Adelia Eagles Stevenson Inez Gannicott* Jillian Horne* Mr. & Mrs. A. Karpluk* David Eastaugh* Jay Garland* Jo-Anne Howe* Brian Klaponski* Dave & Farrell Eckman* Paul Gasse* J. Hubbert* Frank Klemenchuk Charlotte Edgar* Lina Gaudreault* J. Hubscher* Scott Kluczny* Elizabeth Edmison* Giant Tiger Store #80* Ann Huey* George & Elizabeth Knowles* Edna Edwards Audrey Gibson* Gérard Huot Joe & Joan Koole* Tim Ekelund* Stan Gieschen* Alan Husdal* Gene Kosmyna* Bahieldin Elibrachy* Sara Gillespie* Robert Huston* Martin Krippl* Elk Point & District Agricultural Society Gilles E. Girard* Hutchinson Charitable Fund Ktalysis Inc.* Brian Ellerman* Estate of Réjeanne Martel Girard HVAC Inc.* Louis Lacoursière* Estate of Bernice Vera Elliott Janou Girardeau* IATSE Local 891* Patrick Laforge* Jeri Elliott* John Glasier* John Iliffe* Guylaine Landry David & Pearl Elman* Michelle & Torin Glass* Ingredion Canada Corporation Richard Larocque* Henry Ens* Christopher Glover* Joanne Irvine* François Laverdière* Arthur Evans* Eric Godot Andersen J.E. Panneton Family Foundation Alice Leblanc* Dara Fahy* Thomas Goldstein* Edmond Jacques* Ledgir House Ltd.* Fairfax Financial Holdings* Peter Gordon* Bruce & Anita Jamieson Janet Leffek* Louise Fast* Robert Gouinlock* Ileana Jipa* Bernard Lefrançois* Father Thomas Assembly #1321 Normand Goyer* Frances Joaquin* Edwin & Francess Lehtien* Nicole Fear* Renate Greenwood* Marlene Johnston* Edwin Lehtinen Alasdair Fergusson* Beatrice Gregoire* Howard Jones* Lenergy Resources Inc.* Barbara Fidler* Mario B. Giorgio* Emily Joosten* Sylvia Leonard Susan & Rod Finlayson* Renate Grohmann* Lynn Kagan* Les Pros de la Photo (Quebec) Inc.* Margaret Finn* Réjean Guévremont* Sulochana Kamawar* Leslie & Irene Dube Foundation Caroline Fisher* Larry Gulenchyn* Sanjiv Katyal* Francine Letourneau* Lynn Fisher* Gustav Levinschi Foundation Estate of Linda Keane-Luke Jacob Levi* 16 Manitoba Hydro Barbara Novek* Quincaillerie Demers Inc.* Léo Marchand Estate of Hugh Lawrence Nugent H. Peter Quitzau* Louis J. Maroun Laura Nuttall* Vito & Jaclyn Rea* Glenn Marr Sandra Nymark* Brian E. Rainey* Barbara Martin Dr. Paul O’Connor* P. Rasmussen* Joe Matika* O’Connor Family Charitable Foundation Raymond James Canada Foundation Kevin May* Mr. Paul O’Donoghue, in honour of C.R. Rea* Jack Maze* Dr. Michelle O’Donoghue Elaine Reid* Hugh McAdams* Alireza Omidian* John Reid Kenneth W. McArthur* Mark O’Neil* Louise Remark* Alex McComb* O’Neill Foundation Paul & Nancy Ressler* Tara McCool Ontario Power Generation Inc. Employee Ann Rice* Deirdre McDonald* & Pensioners’ Charity Trust Kent Rice* Christina McLeod* Shareen Onyszchuk Nancy Richardson Joan McMillan* Jock & Diana Osler* Barbara Richie* Robert & Junith Mee* Alex Osten Heiner Richter* Barbara Meek* Raynald Ostiguy* Dr. Frank W. Riedl* Roxanna Meek* Robert Pakenham* Lavina Rieger* MEG Energy* John Palmer* Ian & Naomi Ring* Mel’s Diner* Hélène Paquet* Gerard Ringuette* George & Sylvia Melville* Barbara Parker* Marion Robbins* Thank you to our amazing Judith Mewett* Mary Pasquale Laurette Robillard* event participants - you Gary Meyer Dennis R. Passerini* Linda Robinson* Fiorino Mezzanello* Sheila Paterson* Jerome Rogers* help us make a real Derek Milloy* Mark Pelehos* Rogers’ Family Charitable Trust* difference in the lives of Armand & Hazel Misuraca* Pembina Manitou Community Canvass Larry Rooney* Jean-Pierre Mongeau* Inc. Linda Rorabeck* people living with MS. Estate of Doris Elizabeth Montague Armand Perron Barry Rosenberger* Ronald Moore* Bernard Petitclerc* William Ross* Adrian Lo* David Morgan* John Phelan* Margaret E. Ross* Local 222 Union Hall Melissa Morgan* PIC Canada Raymond Rouault Mr. & Mrs. Peter Lockie* John Morin* Claire Pickering* Marilyn & Ray Rousseau* Gus & Mary Anne Longo* Jeanne Morissette* Pilot Mound & District Community Ghislaine Roussel* Anthony Longo* G. Morita* Dr. Ed Pineau Louise Rousselle Trottier* Richard & Carol Loreto* Edwin Mueller* Ward C. Pitfield* Ray & Pam Roy* Ronald Luckman* Mr. & Mrs. Mun H. & Bouck Kim* Mrs. G. Pitman* Ilana & Stephen Ruby* John Macdonald* Don & Jacqueline Murphy* Placements Ionta Inc.* Norman Rusywich* Peter & Linda Macgowan* Joseph Murray* Stephane Plante* Rebecca Rynsoever* John Maclagan* Ann Nakamura* Alice Plotkins* S&C Electric Canada Ltd. William MacTavish* New West Truck Centres* Estate of Mabel Plymate Charles Saillant* Made in the Maritimes Artisan Boutique Iris Nicholaichuk* Serge Poiré* Sakkara Temple No. 115 Daughters of the Michael Madsen* Harold & Dolores Nickerson* D. Ross Pomeroy* Nile Lori Magee Late Margaretha Nikkel Dr. Georgia M. Pontikes* Paul Salmi* Susan & Doug Magnusson James & Barbara Niven* Port Royal MIlls* Sandy Mountain Jamboree 2017* Kimberly Mah* Nixon Charitable Foundation Gerry Price* David Sarles David Mahood Nordson Canada Limited Dominic Proctor* SAS Institute Inc. Thomas Malinowski* Aurise Normandeau* Provincial Employees Community Services Saunders Investment Ltd. Malouf Family Fund Shelly & Alan Norris* Fund Jérôme Saunier* Lloyd & Marcia Manchulenko* Erin Norris* Rosita Przybycien* Fred Sava* Manitoba Egg Farmers Northgrave Medical Inc.* Dick Quan* Jocelyne Sayak* 17 Rodney Schlaak* T.J. Rice Family Foundation Inc. Lisa Wallace* Sarah Schmidt * Francois Tanguay* Evelyn Wallace* Rose Schonblum* Tanya Tierney Team Realty* U. Wallersteiner* Maria Schroeder* Max Tateson* Doug Warne* Scotia Garden Seafood Inc. Donald Taylor* Sylvie Watelle* Susan Senecal* Taylor Family Legacy Foundation James Waters* Margret Sereda* Estate of Esther Teitelbaum John & Josie Watson* Narinder Sharma Telus Corp Wawanesa Insurance Rich Shepherd* Ray & Fenella Temmerman* Rob Weaver* N. Shuttleworth* The Azrieli Foundation Dr. Linda Weber* Arthur I. Silver* The Côté Sharp Family Foundation* Meri Weisman* Silverberg Fund The De Boer Foundation* Joan Weisman* Drs. Sacha Singh & Andie Wiseman* The Gail Asper Family Foundation Inc.* Estate of John Mark Wickett Sisters of Mercy Newfoundland The Gary Bluestein Charitable Foundation Diane Wiebe* Sisters of Providence of St. Vincent de The Honorable Order of the Blue Goose Thomas A. Wilcox* Paul* International - Quebec Pond William C. Stewart Foundation Tom & Angela Skinner* The Jewish Community Foundation of Montreal* Michael R. Williams Gary Slater* The Stoute-Hill Family Fund Michael Williams* Jay Smales The Sussex Area Community Foundation Herb Wimmer* John Smiley* The WB Family Foundation Suzanne Woeller* Samara lives Dr. Allan Smith* The Wolrige Foundation Peter Woodward* with MS, top Scott Smith* Diane Thériault* Carolyn M. Woogh* Susan Smith * Dr. Danny Thibeault C.P. Inc.* Darrell Woolnough* fundraiser for Anita & Edward Smith* Earl Thomas* Jack Wright* MS Walk. Estate of Dorothy Smith Shirley Thompson* Douglas Wright Sobeys National Pharmacy Group Elva Thompson* Robert & Edith Doreen Wright* Mary Souliere* Mary M. Thomson H.D. Wyman* L. Spock* Estate of Tori Eileen Thornton Drs. Mark & Phyllis Yaffe* ST Sales Enterprises* Thorsteinssons LLP Peter Young* St. Joseph’s Villa Estate of Mary Ellen Timmins Brandon Yttri* Roger Stalsberg Jordan Tomlin* Zeller Family Foundation Stan Poulsen Trucking Toronto Prep School Inc.* Donna & Ben Ziarko* Standard Community Chest* Nicole Tremblay* S. Paul Zive* James M. Stanford* Solange Tremblay* Anonymous (47) Trent Stangl* Lynn Troskey* * Was a Research Partner in 2017 STAT Search Analutics* Lorne Trottier* Miranda Steele* Kathryn Troubridge* The MS Society of Canada David Steer* Ivan Trush* would also like to thank Allan Stephens* Joan Trussler* the United Way of Canada Ian Stewart* Éva Turcotte* and all organizations that Donald Stewart* Nancy Turner* offer employee donation Victoria Stikeman* Jane Underwood* programs. Janet Stone* Ruth Van Boven* Boris Subic* Gil & Lori van Buuren* Gerry Suek* Cecil Vance* Sun Life Financial Vantage West Realty Inc. Frank Sus* George Vaughan* Estate of Mary Joy Svoboda W.A. Vautier* Swiss West Foods Ltd.* Victoria Foundation Donald Sylvester* Rita Viger* 18 Evelyn opal society members

The Evelyn Opal Society recognizes an extraordinary group of individuals who have thoughtfully provided a future or planned gift to the MS Society of Canada in support of Canadians affected by multiple sclerosis. With gratitude, we recognize all individuals who have shared with us their intention to make a charitable bequest or other form of legacy gift to the MS Society.

Helen Aello Joan Bernard Suzanne Deschamps Jean Haldane Sandy & Margot Aird Therese Bernard Henry Dewald William Hall Jonathan Allenger Minna Berndt Bill Doekes Wanda Hall Beverly Andersen Gayelene Bonenfant Cheryl Elliott Lydia Hanke David & Rita Arbuthnot Anne Bourne Joan Escubedo M. Patricia Hart Rene Asselin Gregory Bowen Eleanor Esslinger Muriel Hart Jacques Aubertin Laura Brandon Fred Esslinger Sharon Hart Cynthia Bakala Yolanda Bronstein Marilyn Fairclough Sheila Hatton Perry Barbaro Sam Broslow Carole Ferris Helena Hawn Michael Barnes Kathleen Budarick Ray Finlay Bruce Heming Silvie Barrette Cecile Bushko Dona Fitchett Violet Henderson John Barter James Butlin Carrie Fitzsimons Miriam Henning Leonard Bartlett Diane Butlin W. Fleming Patricia Hewitt Jean Bassett Brenda Cardillo Ron Flett Michael Hill Anne-Marie Bastien Dorothy Carnine Benoit Fortin Leah Hogarth H. Beckett Gisèle Carrier et Roland Lebel Alistair M. Fraser Harry Horvath Leola Beckett Barbara Carruthers Carolyn Fedenburg Ralda Howard Odette Bélanger Peter Cassel Carol Fredrek Monica Howell Rita Berendsen Kathleen Cassidy Miklos Fulop Valerie Hussey, C.M. Valerie Chadderton Jacques Furois Gary Huyck Mary Champion Diana & Vito Gandolfo J. Jackson Heidi Charlton Ernie Ganert Bruce Jacobs Ken Chomyn Dorothy Gardner Algis Janusauskas Gerald Chopiany Elspeth Gariepy David Johnston Irene Chopiany Betty Garland Gordon Joice Sylvie Choquette Frances Garritty Tom Jolliffe Élise Clément Louise Gauthier Margaret Jones Yvan Clermont Pierre Gauthier Anna Kaardal Marguerite Clermont Liz Gibson Gale M. Kelly Marie-Josée Comtois Marion Gilchrist Marlene Kennedy Steve Cook Marguerite Gilks Robin Kersey Roxane Cote Robert Gilles Francine Kingsley François Coupal Clare Gillespie Kent Kirkpatrick Angela Crispino Julien Girard Cornelia Kowallek Dennis Cusack Nancy Godwin Rosanne Kozoriz Maureen Czuzman Madeleine Gravel Matthew Kremer Margaret Daugherty Basil Griffis John Krochak Connie Davidson Annie Guay Gloria Kunka Robert Decker Sharon Gustafson Peter Kurita Cathy bone marrow transplant recipient. The den Haan Family Lorraine Hagerman Jerry Kuzmaski 19 Julie Lacroix Nancy Mitchell John & Sharen Robinson* Bill Trbovich Yvette Landry Laurie Modderman Beverly Robinson Janik Tremblay Eric Langin Jean Wickenden Mooney Dan Rollins Daphne Tucker Faulkner Louis Langis Marita Morrow Evelyn Rose Nancy Turner Daniel Larouche Joseph Mulder Steve Roy Mary-Ellen Turner Stéphane Lauzon Eunice Mullen Lorenzo Ruffini Ernest Underwood André Lavergne Evelyn Murdoch Tracy Ruffini Heather Urch Ellen Ledding Kathleen Murphy & Harry Joosten Norman Rusywich Charles Urch James Lee Susan A. Murray Donald S. Rutherford Marie Vaillant Cornelia Leisinger Dorothy Mynen Peter Sartorelli Nellie Valentine François Lespérance Joe Nastiuk Yves Savoie Marion Vanderwood Sherwood Lett Reid & Evelyn Nicholson Lionel Saxby Margaret Vanwyck Marcelle Léveillé Evelyn Nicholson Donna Schlecht Jim Verokosky Carmelle Lewis St-Onge Betty-Lou Northway Teresa Schnurr Thomas Vida Jeanne D’Arc L’Heureux Louella Oberg Al Schoen Linda Walker Betty Livingstone John O’Dwyer Louise Singer Donovan Walker Victor Locke Cathy Ogi Elaine Skistod Sheila Wallin Linda Lumsden Margaret H. Oliver Grant Smalley Carole L. Ward Gordon Lund Jack Osten Bev Smalley Irene Watts Derek Lunden Bob Osterhout Steve Smith Thomas Wells Charlotte Lynch Micheline Ouellet Rita Smith E. Wesolowski Elizabeth Macdonell Kati Ouellet Sheila Smith Anne Whan Elizabeth MacGregor Eric Ouellet Kevin Smith Garry Wheeler Wendy Machan Seka Owen Gladys Smith Beatrice White George MacKenzie Eileen Palmer Rachel Souchereau Joy Wickett William Magee Cathy Paré Wendy Spooner Jean Wilson Janet uses Patricia Maguire Joyce Parker Jean-Guy St. Yves Charles Wilson horse therapy Louise Manuel Ross Parkin Jean Stainton Grant Winterton Henry M. Markey John Paziuk Rosalynn Starkes Janet & Peter Wolfe to help manage Louis J. Maroun Marjorie Paziuk Emma Stewart Brian Woodcock her MS. Donald Maxwell Marg Pearce Ron Stuart Penny Wright Ken & Suzanne Mayhew Sylvie Perrault Gillian Stuart-Lyon* Melanie Yach Gordon McBride Elfriede Perrey Vida Sukys Denise Young Donna McClellan James Perrin Sharon Sundberg Sandra Zagon Julie McDowell Jan Petrar Norma Sutherland Arthur Zutis Bill McElhanney Gloria Pickard Donald Taylor Anonymous (9) Meagan McEwen Dr. Ed Pineau Patricia Taylor * New to the Walter McGimpsey Sandra Popham John Tesseyman Evelyn Opal Society Leigh-Ana McGinity Anne Power Jean Tesseyman in 2017 Linda McGowan K. Power Élizabeth Têtu Gwen McGregor Isabelle Provençal Marie Thibault Louise McGregor W. Rath Karen Thomas Bonnie McKay James Redditt Robert Thomlinson Carolynne McKechnie-Trbovich Richard Rees Graham Thompson Diane Mcleod France Ricard Larus Thorarinson John Medrzyki Bruce & Sylvia Richmond Christiane Thouin David Merrell Hugh Richter Jayne Thrasher Virginia Miller Debra Rigsby Wendy Todd Carolynne Miller Stephanie Robb David L. Torrey 20 Mike Tuohy AB MS Walk/MS Bike: top Fundraisers, Cory Turner ON Dean Unruh AB Teams and Event Donors Greg Van Tighem AB Barbara Van Walleghem MB Gloria Vermeulen BC MS Walk and MS Bike are the MS Society of Canada’s two signature events that unite communities across Canada Millar Weddig ON to unleash the power of collective action. Each year thousands of participants, donors and volunteers come together Voon Wee Yong AB to show their support and help raise millions of dollars to help end multiple sclerosis. Thank you for your outstanding Michael Weinstein MB David Wilton ON contributions. Anonymous NB Top Event Fundraisers $10,000-$19,999 Luke Faubert AB Cynthia Mansfield AB Top Teams We thank the following top Malki & Izzie Abrams ON Chuck Ford NS Sara Marcello ON We thank the following top event event fundraisers who raised Alison Adams ON Nicholas Fowler AB Rob McGrath AB teams who collectively raised more than $10,000 in 2017. All In For MS BC Amanda Fraser AB Darryl Mergaert AB more than $20,000 in 2017. Jonathan Allenger ON Mark Freedman ON Paula Merrier BC $100,000+ $50,000+ Jeff GranbergAB QC Jaclyn Amar ON Louise Michaud Happy Fillmores AB Darcie James BC Jason Guenter AB Ron Bailey MB Bonnie Miller SK Team Cowbell ON Pascale Lavallée QC Bill Bates ON Doug Hansen AB Becky Money AB Barry Travnicek ON Mark Bazerman ON Chuck Hartlen NS Keith Moore ON $75,000-$99,999 $25,000-$49,999 Henriette Benoit ON Myrna Hastings ON Ray Murrell BC Doug and Marion’s MS Erasers ON Lynda Archambault QC Manon Bernard QC David Hawrysh QC Tracey Ostermann ON Les Pédaliers de l’Avenir QC Yves Beaulieu QC Deborah Best ON Meg Henderson ON Jenna Pace ON PCL Construction AB Samara Bleiwas ON Ineke Bezuyen ON Kerry Hetu AB Larry Payne ON Team United Cycle AB Jason Gregor AB Matthew Boswell ON Roland Houle SK Shaun Piercey AB Woop de Woo BC Linda Jarrett ON Salina Bugeaud AB Krysta Inch AB Melvin Porter ON $50,000-$74,999 Luc Lacombe QC Brad Bulger AB Lindsay Ireland ON Griffin Purdy AB Active Physio Works - Team Rehab AB Doug Meloche ON Colin Bulger AB Richard James BC Amar Randhawa AB Bike for Mike ON Suzanne Mignault QC Bernie Burnett ON Julie Jean QC Elaine Rankine ON Butt Ugly ON Keith Mychaluk AB Sharon Byrne ON Nancy Kastner ON Giulia Rea ON eSPrit SPortif QC Julia Nimilowich AB Rick Casson AB Judy Kazakawich AB Elsye Reader SK L.I.A.M.S. TEAM AB Stacey Shein ON Paul Chapman MB Maureen Kerbel ON Brenda Rosychuk AB Lespérance QC Jonathan Simmons ON Dwayne Chapman ON Ken Kerr AB Patrycia Rzechowka AB Menstrual Cycles AB $20,000-$24,999 Morgan Chapman ON Lucas Kessler SK Sal Salvaggio BC Smokin’ Embers AB David Arbuthnot ON Roger Charest QC Jonathan Kleinsasser MB Joyce Santos BC Team Bleiwas ON Tim Blom NB Eric Choi BC Tracy Koluk AB Rejean Savard QC United Construction AB Doug Coleman ON Jake Coady AB Fern Landry ON Luke Schoonderwoerd ON $25,000-$49,999 Scott Davis ON Rick Columbia ON Marc Larocque ON Soren Schou BC Alpine ON Colin Findlay MB Ricky Cormier NB Wayne Lavold AB Reese Shufelt ON Basintek - For the HELLth of it AB Helen Kearns ON John Crawley AB Dawn Leder AB Bryan Simister AB BDO Bikers AB Chris Kieser AB John Cuddie ON Paul Lefebvre AB John Simone ON Bunsen Honeydews AB David Knight ON Ken Cudmore AB Alli LeithoffAB Barry Sullivan AB C.T. Soil’s Mighty Celtic Warriors ON André Lespérance QC Christian Cyr QC Wayne Lessard ON Kevin Tamblyn AB CN QC Timothy Mahoney AB Geneviève Cyrenne QC Nancy Lessard ON Gail Taylor AB Connect2EndMS AB David G. Palmer ON Matthew Dasilva ON Nancy Lester ON Candice Thomas ON Copper Pedalers BC Barry Taylor AB Robert Decker AB Corinne Lotoski AB Christiane Thouin QC Croix Bleue Medavie QC Andrea Trigg AB Tom Dennehy AB Ellen MacGregor AB Marjorie Tibbitts ON Crystal Spring Team MB Arthur Weingarden ON Christie deSouza ON John Makris SK Shaylen Toews AB Cyclepaths MB Julie Dranitsaris ON Juan Manrique AB Faut l’Fer QC DILLON HIGHway ROLLERS ON 21 Friends of Jo-Anne MB $20,000-$24,999 Stacie Sarbaugh Sillworks Gallaghers Grape Escape BC Blazing Saddle Sores SK Luke Schoonderwoerd Sun Life Financial Gears & Beers AB, ON Casson’s Crew AB Transworld Management Ltd. The Canadian Brewhouse Glen’s Titans Never Tire AB Guys and Gals A 1000 Plus ON David & Mary Lynne Wilton The Great-West Life Assurance Company Gluteus to the Maximus ON Jasper Steel Panthers AB Anonymous The International Brotherhood of Electrical Greatful Tread of Great-West Life MB Just Soar AB $5,000-$9,999 Workers I Ride Cause I Can ON Le Kosh Group QC Bennett Jones LLP The Morris and Beverly Baker Foundation Inch by Inch AB Les Générations XYZ QC Canadian Tire Prince Albert Christiane Thouin Industrial Pedalers MB MASS SYNERGY MB Carnivora Tropic Air Systems ITC Skylines AB Mastronardi Produce ON Carter Ford LLP Jeff Turenne Journey for Jani ON Mattamy’s MS Walk for Angela ON CN Valero Energy Keep on Truckin’ ON Misterlegou QC Conam Charitable Foundation Vigilance Santé Kiss MS Goodbye AB Pirate Ship AB Ian Cubitt WHS Foundation MB L’Équipe qui a du chien QC Rozzi’s Riders Marc Daigneault Willis Towers Watson Spicers Canada ON Libro Freewheelers ON Delaney Capital Management Frank & Elaine Wilson Spokes People AB London Life Cycles ON EJS Investments Corp. Yves Giard et André Pearson - 24 h de dek Team Kearns ON Énergir, the new Gaz Métro Loose Sprockets NS hockey Pearson-Giard Team ML QC Equitable Life of Canada Mighty Spinners AB Anonymous (6) Team Spirit ON Fednav Miles for Mo ON The C-Trains ON Fondation Santé Saint-Laurent inc. ON Miles for Smiles The Kitchener BreakAways ON Hon. Michael M. Fortier, P.C. MS AIN’T PURDY AB The Rolling Cause AB FTE Drilling MyButts-Eh-King SK The Spokespeople AB Genzyme Canada MyélinisAction ON Wheelie Good Times NS Go Connect On the Run AB Top Event Donors Greystone Managed Investments PD Slow Riders AB Groupe Leclair We thank the following donors Renew Raging Rollers AB Groupe Tremblay Participants SG Front Forks AB who made an extraordinary gift of Mario Hart enjoying the ride SPinning wheels QC $5,000 or more to an event participant Antonella Iannitti Stellas and Glens and Bikes oh my ON in 2017. Industrial Construction Investments Inc. during MS Bike. Steps for the Cure ON $50,000+ IUPAT Sus Scrofas AB RBC Foundation Ivanhoé Cambridge Team Addison BC Jer’s Corporation $10,000-$49,999 Team Anderson Craft Ales ON KingSett Capital Aimia Team Chris AB Scott Kitching & Barb Van Walleghem Alan & Roula Rossy Family Foundation Team Eramosa ON Les Entreprises Michel Marchand inc. Classique de golf Prémoulé Team Julia AB Allan Markin CN Employees’ and Pensioners’ Community Metro Kopansky Team LAH QC Fund MOD Developments Inc. Team Nervous AB Devon Funtimers Hockey Club MR Menswear Team Stein Club ON Dr. Christopher Moore Dentistry Professional Frank Murgic Teva Canada Innovation/Solutions Corp. NAV CANADA Partagées QC Ember Resources Mike Neumann The Bulger Backers AB Chuck Hartlen Karen Penrice Tour de Ands AB In Memory of Pearl Kirsch RBC Ualberta Bears AB Investors Group RBC Capital Markets VIA Rail Canada QC ITC Management Inc. Roadmap Capital Inc. Vol-au-vent QC Pengrowth Energy Corporation Rona Lespérance West Island Roadrunners QC Patrick Priestner Round Table Management Ltd. Wheelie Awesome Live Wires NS R & D Drywall Inc. SAT Consuling & Construction Inc. 22 Hoffmann-La Roche Ltd NAT I Challenge MS Event Sponsors, IBM Software Sales, Canada NAT Cause Marketing K+S Potash Canada SK From running a marathon to organizing a garage sale, Knight Automotive Group SK Little Short Stop Stores Ltd. ON&NU I Challenge MS empowers individuals to raise money and Corporate Mandarin Restaurants ON&NU in meaningful ways for Canadians living with multiple Manitoba Liquor & Lotteries MB Partners Manulife Financial ON&NU sclerosis. We are pleased to recognize the passionate McKinsey ON&NU individuals who helped raise and inspire contributions of Medavie Blue Cross NAT Through cause marketing campaigns, $20,000 or more to the MS Society of Canada’s critical Morneau Shepell ON&NU employee support, and sponsorship of Mr. Lube Foundation NAT work this past year. our programs and events, thank you Novartis Pharmaceuticals Canada ON&NU, QC Old Dutch Foods Ltd. ON&NU Christine and Carol’s Wedding QC to our corporate partners who make PCL Contructors Canada Inc. NAT Darren Haydar Charity Golf Tournament ON an impact in the lives of Canadians Pizzaville ON&NU Federation Charity Golf Classic AB Plus 1 NAT Golden Gala - by Centutry 21 ON affected by multiple sclerosis. Purolator ATL Hume - Targa Race ON PwC NAT IBEW Local 258 BC A&W Food Services of Canada NAT RBC NAT Let’s Rock n’ Roll MS Away ON Air Canada QC RBC Foundation NAT Nerves of Steel- Jenna Pace & Friends ON Biogen Canada NAT Sanofi GenzymeNAT Night to Fight MS ON Bioscript Solutions NAT Santé Naturelle Adrien Gagnon QC North Peace MS Trail Ride AB Brinks Inc. NAT SAQ QC Pearl Gloves ON D+H Ltd. ON&NU Saskatchewan Blue Cross SK Real and Deal ON Desjardins Group QC Scotiabank NAT Tamarack Ottawa Race Weekend Scotiabank Charity Challenge ON Drive Medical NAT Sentinel Storage AB&NWT, ATL EMD Inc. NAT SimEx Iwerks Entertainment ON&NU Ernst & Young QC Student Works Painting NAT Fairmont Royal York ON&NU Sugoi NAT Erin diagnosed with MS in 2017. Frida Fine Jewellery ATL Sun Life Financial ATL Google NAT Teva Canada Innovation NAT

95 CKNB ATL CTV Northern ON&NU Media Partners 97.3 The Wave ATL Global BC&Y 989 XFM ATL Golden West Radio SK A big thank you to our media Bell Media AB&NWT, ATL, BC&Y Harvard Broadcasting SK Big Dog SK Intrigue Media ON&NU partners for helping promote Black Press BCY MZ Media ON&NU involvement in the MS Society of CHSJ Country 94.1 ATL Newcap Radio (Capital 96.3) AB&NWT Canada’s fundraising events and CJVR/CK750 SK Rogers (Sonic 102.9) AB&NWT Clear Channel Canada ON&NU Saskatoon Media Group SK increasing awareness of multiple Corus Entertainment AB&NWT, ON&NU Shaw Communications SK sclerosis across the country. CTV Atlantic ATL VOCM ATL

Notation: any omission and/or errors are our own and we would be pleased to hear from any donors we may have missed. Please email us at [email protected]. 23 2017 2016 MULTIPLE SCLEROSIS $ $ Revenue Leadership giving activity SOCIETY OF CANADA Bequests 3,657 2,194 endMS Research and Training Network 106 292 endMS Whatever It Takes 1,167 2,140 Combined Statement of Corporate and Individual Giving, Major Donors 3,735 3,529 Grants from governments 1,234 1,218 Revenue and Expenditures Grants from pharmaceutical companies 519 460 Other grants 552 707 For the year ended December 31, 2017 10,970 10,540 (in thousands of dollars) Signature events 18,139 19,124 Direct marketing 10,919 10,688 Local fundraising initiatives 3,786 3,661 To view our full audited financial statements, Partnership events and campaigns 2,895 2,597 I Challenge MS 1,218 1,586 please visit mssociety.ca/financial Gaming 1,415 1,419 United Way and HealthPartners 1,268 1,608 Public awareness activities 599 657 Sale of goods 189 249 Miscellaneous 431 359 Memberships 33 52 Investment income 765 455 52,627 52,995 Fundraising expenditures Leadership giving 1,725 1,852 Signature events 6,371 6,512 Direct marketing 7,587 7,271 Local fundraising initiatives 2,138 2,153 * In addition to our Partnership events and campaigns 444 448 staple research funding I Challenge MS 323 360 Indirect fundraising program, we invested 2,461 2,259 Gaming 157 189 more than $2.8 million Cost of goods sold 128 174 in MS research through 21,334 21,218 the Multiple Sclerosis Scientific Research Program and administration expenditures Client services 7,256 7,921 Foundation (MSSRF). The Research 7,482 6,257 MSSRF is a legal entity Research - endMS Research and Training Network 106 292 separate from the MS Research - endMS Whatever It Takes 1,435 2,330 Society of Canada, and Public education and awareness 4,619 4,844 we generate separate Chapter and volunteer support and development 3,060 3,480 Government and community relations financial statements for 1,139 1,521 MS clinics - 106 the MSSRF. The MSSRF’s Administration 4,649 5,104 T3010 is available on the 29,746 31,855 CRA website. 51,080 53,073

Surplus (deficiency) of revenue over expenditures before the undernoted 1,547 (78) Gain on sale of real estate 2,182 - Research grant to the Multiple Sclerosis Scientific Research Foundation (1,502) - Fair value change in investments (251) 31 Surplus (deficiency) of revenue over expenditures for the year 1,976 (47) 1-800-268-7582 [email protected] MSSOCIETY.CA

NATIONAL OFFICE NATIONAL EXECUTIVE TEAM NATIONAL BOARD OF DIRECTORS BIOMEDICAL RESEARCH COMMITTEE CLINICAL AND POPULATION HEALTH 250 Dundas Street West, Suite 500 RESEARCH REVIEW COMMITTEE Toronto, Ontario Dr. Pamela Valentine Officers Chair, Dr. Fabio Rossi M5T 2Z5 President & chief executive officer Chair, Ms. Valerie Hussey, C.M. Scientific Officer, Dr. Pere Santamaria Chair, Dr. James Sumowski 416-922-6065 Vice-chair, Mr. François Coupal Scientific Officer, Dr. James Marriott Mr. Louis Adam Treasurer, Mr. John Folka Scientific Reviewers BRITISH COLUMBIA & Executive director, Quebec Division Secretary, Ms. Gayelene Bonenfant Dr. Holly Colognato Scientific Reviewers YUKON DIVISION Dr. Shannon Dunn Dr. Tania Bruno Mr. David Arbuthnot Directors 4720 Kingsway, Suite 1103 Dr. Alyson Fournier Dr. Michelle Cameron National vice-president, shared services Burnaby, British Columbia Mr. John Clifford Dr. Marc Horwitz Dr. Charity Evans V5H 4N2 Ms. Marie-Josée Comtois Dr. Cornelia Laule Dr. John Fisk Mr. Benjamin Davis 604-689-3144 Mr. Rahil Dattu Dr. Fang Liu Dr. Gordon Francis President, Atlantic Division; Dr. Thomas Feasby, C.M. Dr. Trevor Owens Dr. Noam Harel National vice-president, government relations Ms. Bonnie Gleim Dr. Manu Rangachari Dr. Victoria Leavitt ALBERTA & NORTHWEST Mr. Chuck Hartlen Dr. Bhagi Sing Dr. Ruth Ann Marrie TERRITORIES DIVISION Ms. Erin Kuan Mr. Joe Healey Dr. Alan Wilman Dr. Kathy Zackowski 9405 - 50 Street, Suite 150 President, Saskatchewan Ms. Susan Senecal Dr. Robin Yates Hotchkiss Edmonton, Alberta & Manitoba Divisions Ms. Christiane Thouin Community Representatives T6B 2T4 Ms. Jennifer White Community Representatives Ms. Sarah Flohr 780-463-1190 Dr. Karen Lee Dr. Sean Wiltshire Ms. Shannon Bachorick Mr. Jason Love National vice-president, research Ms. Jennifer Charters Ms. Kristen Robillard SASKATCHEWAN DIVISION Honourary Members Ms. Karma Deakin-Harb Ms. Sylvia Leonard 150 Albert Street Mr. Alexander (Sandy) R. Aird Mr. Jordan Rosenblood MS SCIENTIFIC RESEARCH FOUNDATION Regina, Saskatchewan Interim president & chief executive officer (2017); Mr. A. Jeremy Arnold National vice-president, talent, programs & services S4R 2N2 Mr. Frank E.P. Bowman ENDMS PERSONNEL AWARDS Officers 306-522-5600 Ms. Laurie Dennett REVIEW COMMITTEE Ms. Lisa McCoy Chair, Ms. Nancy Love Mr. Garrett Herman Vice-chair, President, Ontario & Nunavut Division Chair, Dr. Bradley Kerr Mr. Robert (Bob) Decker MANITOBA DIVISION Mr. Daniel Larouche Treasurer, Mr. Daniel Larouche / Mr. Dwight 1465 Buffalo Place, Suite 100 Ms. Linda Lumsden Ms. Lori Radke Scientific Reviewers Duncan Winnipeg, Manitoba Mr. Lou Maroun National vice-president, marketing & development Dr. Stephen Czarnuch Secretary, Mr. Robert (Bob) Decker R3T 1L8 Dr. William McIlroy Mr. Reid G. Nicholson Dr. Charity Evans 204-943-9595 Directors Mr. Yves Savoie Mr. R. Neil Wickham Dr. Chase Figley President & chief executive officer (2017) The Honourable Céline Hervieux-Payette Mr. Jim Wolfgang Dr. Nader Ghasemlou ONTARIO & NUNAVUT DIVISION Dr. Denis Gris Ms. Diana Joseph 250 Dundas Street West, Suite 500 Ms. Tania Vrionis Dr. Sari Hannila Mr. Paul Mantini Toronto, Ontario President, British Columbia & Yukon Division MEDICAL ADVISORY COMMITTEE Dr. Catherine Larochelle Mr. David Mindell M5T 2Z5 Dr. Craig Moore Mr. Joseph Randell 416-922-6065 Dr. Garry Wheeler Chair, Dr. Ruth Ann Marrie Dr. Dalia Rotstein Mr. Cory Turner President, Alberta & Northwest Territories Division Dr. David Rudko Mr. Rick Waugh QUEBEC DIVISION Members Dr. Yunyan Zhang Ex-officios 550 Sherbrooke Street West Dr. Nathalie Arbour Ms. Valerie Hussey, C.M. Suite 1010, East Tower Dr. Brenda Banwell Community Representatives Ms. Sylvia Leonard (2017) Montreal, Quebec Dr. Timothy Coetzee Mr. Denis Baribeau Mr. Bruce Richmond (past chair) H3A 1B9 Dr. Samuel David Ms. Lynda Gregson Mr. Yves Savoie (2017) 514-849-7591 Capt. Yanick Drouin Ms. Beverley MacAdam Dr. Thomas Feasby, C.M. Ms. Heidi Pylypjuk Dr. Pamela Valentine Dr. Anthony Feinstein ATLANTIC DIVISION Dr. Marcia Finlayson Executive Director 109 Ilsley Avenue, Unit 1 Ms. Valerie Hussey, C.M. Ms. Lori Radke Dartmouth, Nova Scotia Dr. Wayne Moore B3B 1S8 Dr. Trevor Owens Honourary Patrons 902-468-8230 Dr. Scott Patten Mr. Alexander (Sandy) R. Aird Mr. Cory Turner Ms. Helen Kearns Mr. Lou Maroun Mr. Bruce Richmond Mr. Richard Thompson Mr. David L. Torrey Cover image: Christine Sinclair, Thorns FC; Jessica Fishlock, Reign FC. Photo courtesy of Thorns FC. Photographer: Craig Mitchelldyer.