„Discovery Consists of Looking at the Same Thing As Everyone Else and Thinking Something Different.”

„Discovery consists of looking at the same thing as everyone else and thinking something different.”

Albert Szent-Györgyi Nobel laurate (1893-1996)

19th Budapest nephrology School 2012. 08. 26-31

WELCOME TO BUDAPEST Prof. Dr. László Rosivall DSc.

Head of Department of Pathophysiology, International Nephrology Research and Training Center, Doctoral School of Basic Medicine at Semmelweis University, Hungarian Kidney Foundation WELCOME TO BUDAPEST Prof. Dr. László Rosivall DSc.

Head of Department of Pathophysiology, International Nephrology Research and Training Center, Doctoral School of Basic Medicine at Semmelweis University, Hungarian Kidney Foundation Content

1.) Hungary at a Glance 2.) Why Hungary? 3.) Peculiarities of Budapest Nephrology School

Mini review, Special view,

On Big issue, For you! Hungary at a Glance

Established 896, The first Christian King was coronated in 1001

„sacred crown”

Hungarian coronation St. Stephen (970-1038) jewels Hungary at a Glance

Territory: 93 000 km2 „Are you aware that there is a language that because of its constructive ability Population: < 10 million and the harmony of its rythm I have (demographic ratio <1) placed on the same level as Greek and Population density: ~100 person/ Latin? It is the Hungarian language! I km2 know the poems of the new Hungarian poets and their musics has completely Official language: Hungarian enchanted me.” (Finno-Ugrian) Cardinal Giuseppe Mezzofanti (1774 – 1849) European Union, 2004 Watts transaction of the Phylological Soc. 1855 Hungary at a Glance Hungarian origin Nobel Laureates: 17

Fülöp Lénárd (1862-1947) physics 1905 Róbert Bárány (1876-1936) medicine 1914 Richard A. Zsigmondy (1865-1929) chemistry 1925 Albert Szent-Györgyi ( 1893-1986) medicine 1937 György Hevesy (1885-1966) chemisty 1943 Isidor Isaac Rabi (1898-1988) physics 1944 György Békésy (1899-1972) medicine 1961 Jenő Wigner (1902-1995) physics 1963 Dénes Gábor (1900-1979) physics 1971 Daniel Carleton Gajdusek (1923-08) medicine 1976 Milton Friedman (1912-2006) economy 1976 Elie Wiesel (1928- peace 1986 János Polányi (1929- chemistry 1986 György Oláh (1927- chemistry 1994 János Harsányi (1920-2000) economy 1994 Imre Kertész (1929- literature 2002 Ferenc Hersko (1937- chemistry 2004

Country-wise distribution of Nobel prize until 2006

Countries with Most Golden Medals Summer Olympics Some Hungarian Scientists:

Farkas and János Bolyai mathematics (1775-1856, 1802-1860) Tivadar Puskás physics (1844-1893) Tódor Kármán physics (1898-1988) Neumann János mathematics (1903-1957) Jenő Wigner atomic physics (1902-1995) Leo Szilárd atomic physics (1898-1964) Ede Teller atomic physics (1908-2003) Pál Erdős mathematics (1913-1996) Rubik Ernő architect (1944 - Arts, Musicians

Ferenc Liszt Ferenc Erkel Ferenc Lehár Imre Kálmán Zoltán Kodály Ernő Dohnányi Béla Bartók János Ferencsik György Solti György Ligeti Lajtha László Zoltán Kocsis Background - History of the Hungarian nephrology - Strong start at turn of 19th/20th century

von Sándor Korányi 1866 - 1944

FIRST:

- applied freezing point reduction to measure osmotic activity of urine

- measured renal function by concentrating ability

- coined the term „renal insufficiency” and „hypostenuria”

History of Nephrology Pictures from Portraits of Pioneers in European Nephrology

Interviews by Giorgina B. Piccoli Images by Gilberto Richiero With a text by Giorgio Cattaneo MELLI, Turin, 2012 Speciality of Hungarian Nephrology

- Postgradual education, 46 PhD in NRTC, Budapest (1994-) - Holistic, bio-psycho-socio-spiritual approach, - Special rehabilitation, Patient-run dialysis unit - Psychonephrolgy practice and Bálint-Groups for Dialysis Nurses - Idea of World Kidney Day - Hungarian Kidney Foundataion, Budapest Nephrology School

- Brake in further development of nephrology at eighties

- Establishment of Hungarian Kidney Foundation 1987

Establishment of Hungarian Kidney Foundation

Established: Strategic plans: In 1987 by Laszlo Rosivall - provision of grants by applications - establishment of Nephrology Type: Research and Training Centre, 1990 Charity, public foundation - academic nucleus by inter-departmental network Aim: - training young talented nephrologists To support the development at international levels of education, research and - establishment of PhD program, 1993 clinical practice of nephrology - establishment of an international refreshing course, 1994 - establishment of Awards Idea of Budapest Nephrology School - early nineties: HKF and ISN Suggestion to Ike to support a regional education center in Central Europe to foster the development of nephrology in ex-socialist countries

Benefit - low cost - convenient location - easy follow up - easy understanding

Outcome Education and training of critical number of physicians and researchers from Hungary and neighbouring countries: Training of about 1000 physicians at postgraduate level and 150 at graduate level About the School Wonderful international faculty

T. Andreoli Faculty Members of the BNS (127) I.D. Sclöndorff A. MacLeod J. Balla A. Falus N. Ismail H. Schmidt-Gayk O. Mehls J. M. Bargman Cs. Farsang B. Iványi G. Schulman D. C. Mendelssohn C. Baylis J. Feehally K. Jager K. Skorecki A. Meyrier P. Bárány M. Fischereder J. Járay E. Slatopolsky I. Mucsi P. D. Bell L. G. Fine V-M. Kahari S. Sonkodi S. Mustata W. van Biesen J. Floege K. Kauser G. Spasovski G. A. Müller R. Blantz A. Fogo D. Kerjaschki A.Spät H. Mürer B. M. Brenner D. Fouque Z. Stevanovic J. T. Kielstein J. Nagy M. E. De Broe M. Geiszt I. Kiss D. Naimark T. Szabó R. de Châtel P. Gergely H. Klinkmann S. Nielsen B. Szamosfalvi D. Cohen D. Goldsmith E. Kolossváry M. Novák M. Tapolyai R. Oberbauer E. Cole M. S. Goligorsky G. Kovács V. Tesar K. Olgaard A. J. Collins S. Goral Cs. P. Kovesdy A.Tislér H. H. Parving R. Coppo J. G. Grunfeld J. Titze R. T. Krediet M. Paul W. Couser S. Halperin S. W. Tobe K. Kurokawa F. Perner Á. Haris A. Covic S. Van Laecke J. Peti-Peterdi T. Tóth L. Harper P. Csermely R. Pisoni T. Tulassay U. Heemann N. Lameire A. Davison J. Rees S. Vas A. Heidland R. Langer E. Ritz Gy. Deák J. H. Helderman A. Logan P. Venetianer B. Rodríguez-Iturbe G. Devins G. Hercz N. Levin J. J. Weening P. Ronco J. Dirks L. Hunyadi M. Little A. Wiecek L. Rosivall E. J. Holtzman F. Locatelli T. B. Drücke B. Rutkowski I. Wittman A. Horváth G. M. London Cs. Dzsinich I. Rychlik D. De Zeeuw F. Luft K-U. Eckardt A. Iaina B. Sarkadi P. Å. Zillén

Thomas E. Andreoli (1935–2009)

„Thomas E. Andreoli, a towering figure of American medicine, died on 14 April 2009. He was Distinguished Professor and Chair Emeritus of Internal Medicine at the University of Arkansas for Medical Sciences College of Medicine and past president of both the International Society of Nephrology and the American Society of Nephrology. Although he retired as chair in 2004, he remained fully engaged in teach ing and attending on the clinical service. At the time of his death he was editing the eighth edition of his beloved Andreoli and Carpenter's Cecil Essentials of Medicine.” KI Participants - from the region - now from all over the world Education of more than 1000 nephrologists

Participant’s Countries (57) from 4 Continents

Albania Egypt Kasachstan Romania Algeria England Kenya Russia Austria Estonia Latvia Serbia and Bahrein France Libya Montanegro Belarus Germany Lithuania Slovenia Belgium Greece Macedonia Slovakia Bosnia and India Moldova South Africa Herzegovina Indonesia Mongolia Sri Lanka Brazil Iran Netherlands Sweden Bulgaria Israel New Zealand Switzerland Canada Italy Nigeria Turkey China Japan Norway Ukraine Croatia Jordan Pakistan United Kingdom Czech Repubilc Jugoslavia Poland USA Denmark Venezuela Portugal

Support: HKF, ISN, ERA-EDTA scholarships, lecturers ERA-EDTA and Hungarian Kidney Foundation Fellows

PhD Students ERA-EDTA Fellows

HR Josipovic, Josipa HU Abhari, Sina

HU Dégi, Arianna HU Gombos, Petra

HU Hegedűs, Péter Hungarian Kidney Foundation HU Mészáros, Krisztina Fellows HU Németh, Adrienn HR Kruzljak, Vladimir HU Szalay, Csaba SE Nešić, Aleksandar HU Várady, Tímea

This year:

- 25th Anniversary of the Hungarian Kidney Foundation - 19th Anniversary of the Establishment of the Budapest Nephrology School

- 7th World Kidney Day

- 10th International Symposium on Wine and Health

- Poster Presentation

- Faculty, Fellows, Accreditation, Book, Evaluation, Certification

Faculty of the 19th Budapest Nephrology School

Ernő Péter Botos János Peti-Peterdi Marc E. De Broe György Reusz Monika Gooz Eberhard Ritz Simin Goral Steven Rosansky Ágnes Haris László Rosivall J. Harold Helderman Gerald Schulman Béla Iványi Goce Spasovski István Kiss Balázs Szamosfalvi Csaba P. Kovesdy Ágoston Szél Róbert Langer Jens Titze Friedrich C. Luft Tibor Tóth István Mucsi Tivadar Tulassay Márta Novák Andrzej Wiecek Rainer Oberbauer

Thomas E. Andreoli Eberhard Ritz László Rosivall

655 pages, 2nd edit. ISBN 963 218 8322 State Printing Co Budapest, 2006 Accreditation

The 19th Budapest Nephrology School is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) for 30 European CME credits (ECMEC's).

The Course includes 46 hour scientific lectures and a final examination which can be locally evaluated according to national standards (in Hungary it is equal to 50 CME credits). Please have it always with you, and fill it out time to time Certification will be only given to those who

- actively participate - are always present - fullfil the evaluation forms Commentary

„… Budapest School … one of the best of its kind. We congratulate …” Jan J. Weening, ISN Past President

„…As a President of ERA-EDTA association I’m very proud that our Society is a sponsor of the Budapest Nephrology School …” Francesco Locatelli, Past President of ERA-EDTA

„ … The Semmelweis University under the dedicated leadership of Professor Rosivall has developed the tradition of an annual Nephrology Summer School in Budapest… The panel of experts is impressive and has included some of the top leaders of nephrology in the world…” Eberhard Ritz, ISN Past President, Andrzej Wiecek, ERA-EDTA CME Council

„Great work, worth to recommend to colleagues.” A participant The Hungarian Wisdom St. Stephen, King of Hungary (969-1038): „Concerning the Reception of Foreigners, and the Support of Strangers.

In strangers and men from abroad there is such great utility that it can be held worthy the sixth place in regal dignity.

For as strangers come from diverse regions of the provinces, they bring with them diverse languages and usages, and diverse learning and arms, all of which not only adorn the royal palace and render magnificent the court, but also abash the arrogance of aliens. For a kingdom of one tongue, or of one custom, is weak and fragile.

Wherefore I bid you, my son, support those persons with a good will, and treat them fairly, that they may prefer to continue with you rather than to live elsewhere.”