DOCSLIB.ORG

ASP NEWSLETTER VOLUME 51, ISSUE 4 PAGE 2 Ōmura: 2015 Nobel Laureate in Medicine Memoriam: David J

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
ASP NEWSLETTER VOLUME 51, ISSUE 4 PAGE 2 Ōmura: 2015 Nobel Laureate in Medicine Memoriam: David J The American Society Discovering Nature’s of Molecular Potential PharmacognosyThe ASP Newsletter: Volume 51, Issue 4 ASP Fellow Ōmura In Memoriam Awarded Nobel Prize David J. Slatkin By Drs. James B. McAlpine and David J. Newman By Drs. Paul L. Schiff Jr., Melany Puglisi-Weening, and John H. Cardellina II r. Satoshi Ōmura was one of three n November 16, 2015 Nobel Prize 2015, David Joseph winners in Physiol- Slatkin, PhD, for- Dogy or Medicine. The ASP mer Treasurer and was “ahead of the game,” Olongtime Honorary Member as he was the Norman of the ASP, passed away R. Farnsworth awardee after a long battle with Par- at the 2013 ASP Annual kinson’s disease. Many ASP Meeting for his superb members are likely to think work in antibiotics and of David as the long time related compounds; he ASP Treasurer who was a also became an ASP Fel- driving force in growing the Drs. McAlpine and Ōmura. low as a result of this Society’s financial holdings, award by the Society. It is propitious that ASP recognized his stature but Professor Slatkin was Dr. David Slatkin before the award of the Nobel Prize for Medicine this year for his also one of the country’s work on the avermectin/ivermectin class of microbial metabolites, most influential pharma- sharing the award with Dr. William Campbell, originally from Merck cists, spending most of his career making tremendous Sharp and Dohme, (one half the award to these two gentlemen) and contributions to pharmocognosy and pharmacy education. the other half to Dr. Tu Youyou for her work on artemisinin. Born in Brooklyn, New York, David was the third of four Dr. Ōmura has the phenomenal number of 1,108 cited docu- children of Max and Bertha (Schwartz) Slatkin. He grew ments in Scopus, a total citation count of 25,420 (as of Novem- up in Scarsdale, New York, and graduated from Scarsdale ber) and an h factor of 68 (since 1996). These figures demon- High School. He earned baccalaureate degrees from Wayne strate the immense effect that he has had during his scientific State University, Detroit, Michigan, and Mercer University’s career investigating molecules from terrestrial microbes. Southern School of Pharmacy, Atlanta, before pursuing Dr. Ōmura was born in July of 1935 and has the distinction of hav- Masters and PhD degrees from the School of Pharmacy, continued on page 3 continued on page 3 See ‘Snow on Red Plum Blossoms’ p.7 ASP Travel Awards Deadline p.17 IN THIS ISSUE: WINTER 2015 Editor’s Corner 2 Fun With Pharmacognosy 16 Meet a New Member 21 Mitscher Honorary Issue 6 3D Printing for the Natural Products Laboratory New Members 22 Snow on Red Plum Blossoms 7 ASP Travel Awards 17 Conference Calendar 23 JNPC2016 in Copenhagen 12 Pharmacognosy Field Notes 18 Brief News from Washington 24 ASP Interim Meeting: Oxford, Mississippi 13 Chatham Fellowship From the Archives 26 ASP Past Secretary Keller: 14 ASP Fellows 19 The Nobel Prize and the ASP 30 Years of Loyal Service What Are We Missing www.pharmacognosy.us EDITOR’S CORNER EMPLOYMENT SERVICE was truly a momentous time in history for the 2015 discipline of pharmacognosy. The Nobel Prize The Society offers a in Physiology or Medicine was awarded to scientists placement service to aid who conducted pharmacognosy research that led to our members in seeking cures for parasitic diseases. As I traveled to China positions or employees. in late 2015, I was struck by the amount of press This service is available that one of these Nobel Laureates, Tu Youyou, only to ASP members and received in her country. I saw newspapers and is free to both the appli- magazines with major front page articles on her cant and the employer. accomplishments in discovering a new cure for For more information see malaria from the wormwood plant. I was most the services website. impressed that a small gift shop in the Drum www.pharmacognosy.us/jobs/ Tower Hutong area of Beijing had a specimen of Artemisia on display with a note congratulating Youyou Tu on her Nobel work in phytochemistry. Pharmacognosy is certainly being appreciated by people more widely thanks to this recognition from the Swedish Academy. NEWSLETTER This Nobel announcement also marked the first time in which a member of the Ameri- STAFF can Society of Pharmacognosy was recognized with a Nobel Prize. ASP Fellow, Dr. Satachi Ōmura, was presented with this honor in Stockholm, Sweden in December 2015, and ASP Treasurer, Dr. James McAlpine, was on hand to witness this historic event for the Society Edward J. Kennelly, Ph.D. and for the pharmacognosy world at large. Our lead article, written by ASP Fellow Dave Editor-In-Chief Newman, along with Dr. McAlpine, goes into detail about Dr. Ōmura’s research in natural Amy C. Keller, Ph.D. products that produced a drug that has ultimately almost eradicated river blindness. Drug Assistant Editor discovery with such significant impact on human health is a goal many ASP members Nancy Novick dream of, but only a few have been able to achieve. Design & Production In addition to celebrating this Nobel achievement, we also mark the death of Dr. David Devhra BennettJones Slatkin. David served the Society for decades as our Treasurer. In the old days when we Gordon Cragg, Ph.D. mailed in checks for ASP dues, David was the first person many of us interacted with in Kevin Tidgewell, Ph.D. the Society. I attended the memorial service for David in November in suburban Chicago, ASP Newsletter Committee and I was struck by his commitment to his lovely family, his work as founding dean of three The contribution deadlines are: colleges of pharmacy, his synagogue, and the American Society of Pharmacognosy. ASP Spring Issue Feb. 15 was an integral part of David’s life professionally, but also personally. Speaking with his Summer Issue May 15 wife, she recalled family vacations that revolved around ASP meetings, and the Slatkin din- Fall Issue Aug. 15 ingroom table filled with ASP newsletters that would be labeled and mailed out from their Winter Issue Nov. 15 home in the days before email. I am very grateful to David and the entire Slatkin family for Please send information to: their devotion to the ASP, and I am honored that the Slatkin family asked that contributions Edward J. Kennelly, Ph.D. be made in his honor to the ASP Foundation. I have already done so, and I hope that other Editor In Chief, ASP Newsletter members who knew David well will also consider doing this. http://www.pharmacognosy. Department of Biological Sciences us/what-is-pharmacognosy/the-asp-foundation/ David’s legacy in ASP will live on in many Lehman College, CUNY ways, including the hard work of his daughter, Laura Stoll, as ASP Business Manager. 250 Bedford Park Blvd. West We honor another long-time ASP member, former ASP Secretary Dr. Bill Keller, for his de- Bronx, NY 10468 cades of work for the Society. Bill has stepped down as Secretary in 2015, and his work for 718-960-1105 the Society is considered in a piece by Dr. Douglas Kinghorn. As you plan your conference attendance for 2016, I hope you will consider going to 9th Joint Natural Products Confer- [email protected] ence, to be held in Copenhagen, Denmark, from July 24-27. ASP will be one of the hosts of ISSN 2377-8520 (print) this joint meeting, and it is a great way to make contacts with our European colleagues in ISSN 2377-8547 (online) pharmacognosy. If you are not able to make it to Europe this summer, please consider com- ing to the the joint 16th International Conference on the Science of Botanicals with the ASP Interim Meeting, to be held in Oxford, Mississippi, April 11-14. I hope 2016 is a wonderful Above: Beijing gift shop display of and productive year for you, and I hope to see you in Copenhagen or Oxford. Artemisia annua with hand written note about 2015 Nobel Prize awarded to Tu Dr. Edward J. Kennelly Youyou for her work on this species. THE ASP NEWSLETTER VOLUME 51, ISSUE 4 PAGE 2 Ōmura: 2015 Nobel Laureate in Medicine Memoriam: David J. Slatkin continued from page 1 continued from page 1 ing not one, but two PhDs, the first in Pharmaceuti- University of Mississippi (Ole Miss), Oxford, Mississippi. It was cal Sciences from the University of Tokyo, Tokyo, there at Ole Miss that a young assistant professor, Dr. Paul Japan, in 1968 and the second in Chemistry from Schiff, first met David and worked with him on several projects the Tokyo University of Science, Tokyo, Japan, his that eventually became an important part of David’s doctoral alma mater, in 1970. Aside from two years as a re- dissertation research; these projects involved a study of the search associate at the Yamanashi University, Kofu, constituents of Cocculus carolinus roots and Cannabis sativa Japan, he has spent the whole of his scientific career at the Kitasa- roots. Dr. Schiff recalls his first impressions of David as “… to Institute, Tokyo, Japan, first as a researcher, then rising through intelligent; focused; energetic; ambitious; likeable; and pos- the ranks until his appointment as President in 1990, followed by sessing an unmistakable kinesis in his actions and manner.” appointment as President Emeritus from 2008 to 2012, and is cur- Wherever “Slats” was, things were happening! rently a “Distinguished Emeritus Professor and Special Coordinator He joined the faculty at Northeast Louisiana University School of the Research Project for Drug Discovery from Natural Products of Pharmacy, Monroe, Louisiana, in 1971.
Load more

Recommended publications
  • 書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
    書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S.
    [Show full text]
  • Simulating Physics with Computers
    International Journal of Theoretical Physics, VoL 21, Nos. 6/7, 1982 Simulating Physics with Computers Richard P. Feynman Department of Physics, California Institute of Technology, Pasadena, California 91107 Received May 7, 1981 1. INTRODUCTION On the program it says this is a keynote speech--and I don't know what a keynote speech is. I do not intend in any way to suggest what should be in this meeting as a keynote of the subjects or anything like that. I have my own things to say and to talk about and there's no implication that anybody needs to talk about the same thing or anything like it. So what I want to talk about is what Mike Dertouzos suggested that nobody would talk about. I want to talk about the problem of simulating physics with computers and I mean that in a specific way which I am going to explain. The reason for doing this is something that I learned about from Ed Fredkin, and my entire interest in the subject has been inspired by him. It has to do with learning something about the possibilities of computers, and also something about possibilities in physics. If we suppose that we know all the physical laws perfectly, of course we don't have to pay any attention to computers. It's interesting anyway to entertain oneself with the idea that we've got something to learn about physical laws; and if I take a relaxed view here (after all I'm here and not at home) I'll admit that we don't understand everything.
    [Show full text]
  • NO TRONO DA CIÊNCIA I: MULHERES NO NOBEL DA FISIOLOGIA OU MEDICINA (1947-1988) Elas Proferiramduranteassolenidadesdepremiação
    TEMA EM DESTAQUE NO TRONO DA CIÊNCIA I: MULHERES NO NOBEL DA FISIOLOGIA OU MEDICINA (1947-1988) LUZINETE SIMÕES MINELLA RESUMO NO TRONO DA CIÊNCIA I: MULHERES NO NOBEL DA FISIOLOGIA OU MEDICINA (1947-1988) FISIOLOGIA CIÊNCIA I: MULHERES NO NOBEL DA NO TRONO DA O artigo reflete sobre as trajetórias das cinco cientistas que receberam o Nobel na Fisiologia ou Medicina entre 1947 e 1988, abordadas como as pioneiras dessa área no curso desta premiação criada em 1901. Numa perspectiva balizada pelos avanços da crítica feminista à ciência, dos campos de gênero e ciências e da história das ciências, o artigo sintetiza vários aspectos ligados às origens e formação dessas mulheres, ressaltando as interferências de gênero na construção das suas carreiras. A discussão visa a contribuir para o debate sobre a categoria feminização. Foram consultadas várias fontes, entre elas o site do prêmio no qual podem ser encontradas suas autobiografias, bem como os discursos e palestras que elas proferiram durante as solenidades de premiação. MULHERES • PRÊMIO NOBEL • FISIOLOGIA • MEDICINA IN THE REALM OF SCIENCE I: WOMEN NOBEL PRIZE IN PHYSIOLOGY OR MEDICINE (1947-1988) ABSTRACT The article discusses the path of the five women scientists who received the Nobel Prize in Physiology or Medicine, between 1947 and 1988, regarded as pioneers in this area in the course of this award created in 1901. In a perspective marked by advances in feminist criticism of science, in the fields of gender and science and the history of science, this article summarizes various aspects linked to the v.47 n.163 p.70-93 jan./mar.
    [Show full text]
  • Spring-8 Highlights 2014
    Three‐way Meeting 2015 27th ‐28th Feb. 2015 SPring‐8 Highlights 2014 Photo by Shigeki Tsujimoto Masaki Takata RIKEN SPring‐8 Center 1 How SPring‐8 really works? What is benefits of Science? 2 It was important to map SPring‐8 in society as well as science community. 3 Overview • Building Brand • Expanding Cooperation • Increasing Awareness • Shaping Future 4 Building Brand • Tissue Engineering • Critical Materials Strategy • Quantum Nano Dynamics • SR Magnetism • Nano Applications 5 Tissue Engineering Cardiac Regenerative Nobel Laureate Therapy Using Cell Sheets S. Yamanaka Integration of iPSC‐cardiomyocytes in the Heart non‐invasive investigation of regional beating of cardiac muscle Prof. Yoshiki Sawa Dept. of Cardiovascular Surgery Osaka University iPSC‐CMs‐ transplanted heart day 14 Showing synchronized contraction of the iPSC‐CMs sham‐operated in the sheet. heart Arrows indicate timing of end diastole. SAXS: Regional beating of Rat heart CT‐1353 Accepted 12/20/2014 for publication in “Cell Transplantation” 6 Critical Materials Strategy Elements Strategy Initiative Center for Magnetic Materials (ESICMM) Smart Visualization for Domain Engineering Kazuhiro Hono A key tool to quest for Dy‐free Nd‐Fe‐B Permanent Magnets NIMS Fellow Director of Magnetic Materials Unit BL25SU: Soft X‐ray Soft X‐ray Nano Spectroscopy Beamline; BL25SU Nano Application Since 2014 7 Critical Materials Strategy Elements Strategy Initiative Center for Magnetic Materials (ESICMM) Micro Magnetic Simulation Concerted with SPring‐8 A key tool to quest for Dy‐free Nd‐Fe‐B Permanent Magnets Shinji Tsuneyuki University of Tokyo, Computational Materials Science Initiative Domain information upgrades a simulation technology. K‐Computer H. Sepehri-Amin et al., 8 Scripta Mater.
    [Show full text]
  • Race in the Age of Obama Making America More Competitive
    american academy of arts & sciences summer 2011 www.amacad.org Bulletin vol. lxiv, no. 4 Race in the Age of Obama Gerald Early, Jeffrey B. Ferguson, Korina Jocson, and David A. Hollinger Making America More Competitive, Innovative, and Healthy Harvey V. Fineberg, Cherry A. Murray, and Charles M. Vest ALSO: Social Science and the Alternative Energy Future Philanthropy in Public Education Commission on the Humanities and Social Sciences Reflections: John Lithgow Breaking the Code Around the Country Upcoming Events Induction Weekend–Cambridge September 30– Welcome Reception for New Members October 1–Induction Ceremony October 2– Symposium: American Institutions and a Civil Society Partial List of Speakers: David Souter (Supreme Court of the United States), Maj. Gen. Gregg Martin (United States Army War College), and David M. Kennedy (Stanford University) OCTOBER NOVEMBER 25th 12th Stated Meeting–Stanford Stated Meeting–Chicago in collaboration with the Chicago Humanities Perspectives on the Future of Nuclear Power Festival after Fukushima WikiLeaks and the First Amendment Introduction: Scott D. Sagan (Stanford Introduction: John A. Katzenellenbogen University) (University of Illinois at Urbana-Champaign) Speakers: Wael Al Assad (League of Arab Speakers: Geoffrey R. Stone (University of States) and Jayantha Dhanapala (Pugwash Chicago Law School), Richard A. Posner (U.S. Conferences on Science and World Affairs) Court of Appeals for the Seventh Circuit), 27th Judith Miller (formerly of The New York Times), Stated Meeting–Berkeley and Gabriel Schoenfeld (Hudson Institute; Healing the Troubled American Economy Witherspoon Institute) Introduction: Robert J. Birgeneau (Univer- DECEMBER sity of California, Berkeley) 7th Speakers: Christina Romer (University of Stated Meeting–Stanford California, Berkeley) and David H.
    [Show full text]
  • Baruch S. Blumberg 1925–2011
    Baruch S. Blumberg 1925–2011 A Biographical Memoir by W. Thomas London ©2014 National Academy of Sciences. Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. BARUCH SAMUEL BLUMBERG July 28, 1925–April 5, 2011 Elected to the NAS, 1975 Baruch S. Blumberg was a research scientist who received the Nobel Prize for Physiology or Medicine for his discovery of the Australia antigen, one of the most important advances in the field of Hepatology. Known to everyone as Barry, he was an unlikely person to have made the discoveries that had such a huge impact on public health, liver disease, infectious disease and virology. Barry was not a virologist, a hepatologist, an infectious disease specialist, or an epidemiologist. He had minimal clin- ical training in medicine and no formal training in those other disciplines. He was, in fact, more of a 19th century natural scientist than a 20th century laboratory or clin- ical scientist. Finding the cause of viral hepatitis was not what he had in mind when he began his research career. By W. Thomas London Yet Barry’s discovery, made with teams in Philadelphia and Bethesda, led to the virtual elimination of transfusion-related hepatitis B in most parts of the world, and was essential to the identification of hepatitis A, C, D, and E viruses. When he identified the Australia antigen as the outer coat of the previously unidentified hepatitis B virus, it was the prelude to the invention of the first vaccine to prevent infection with the virus, the demonstration of its association with acute and chronic hepatitis B, cirrhosis, and liver cancer, and ultimately the prevention of liver cancer.
    [Show full text]
  • Prehľad Dejín Biológie, Lekárstva a Farmácie
    VYSOKOŠKOLSKÁ UČEBNICA UNIVERZITA PAVLA JOZEFA ŠAFÁRIKA V KOŠICIACH PRÍRODOVEDECKÁ FAKULTA Katedra botaniky Prehľad dejín biológie, lekárstva a farmácie Martin Bačkor a Miriam Bačkorová Košice 2018 PREHĽAD DEJÍN BIOLÓGIE, LEKÁRSTVA A FARMÁCIE Vysokoškolská učebica Prírodovedeckej fakulty UPJŠ v Košiciach Autori: 2018 © prof. RNDr. Martin Bačkor, DrSc. Katedra botaniky, Prírodovedecká fakulta, UPJŠ v Košiciach 2018 © RNDr. Miriam Bačkorová, PhD. Katedra farmakognózie a botaniky, UVLF v Košiciach Recenzenti: doc. RNDr. Roman Alberty, CSc. Katedra biológie a ekológie, Fakulta prírodných vied, UMB v Banskej Bystrici doc. MVDr. Tatiana Kimáková. PhD. Ústav verejného zdravotníctva, Lekárska fakulta, UPJŠ v Košiciach Vedecký redaktor: prof. RNDr. Beňadik Šmajda, CSc. Katedra fyziológie živočíchov, Prírodovedecká fakulta, UPJŠ v Košiciach Technický editor: Mgr. Margaréta Marcinčinová Všetky práva vyhradené. Toto dielo ani jeho žiadnu časť nemožno reprodukovať, ukladať do in- formačných systémov alebo inak rozširovať bez súhlasu majiteľov práv. Za odbornú a jazykovú stránku tejto publikácie zodpovedajú autori. Rukopis neprešiel redakčnou ani jazykovou úpravou Tento text vznikol aj vďaka materiálnej pomoci z projektu KEGA 012UPJŠ-4/2016. Vydavateľ: Univerzita Pavla Jozefa Šafárika v Košiciach Dostupné od: 22. 10. 2018 ISBN 978-80-8152-650-3 OBSAH PREDHOVOR ................................................. 5 1 STAROVEK ................................................ 6 1.1 Zrod civilizácie ........................................................8
    [Show full text]
  • The Research Imperative Arnold Theiler Memorial Lecture 2017
    The Research Imperative Arnold Theiler Memorial Lecture 2017 Robert O. Gilbert, FRCVS Professor, Ross University School of Veterinary Medicine Professor Emeritus, Cornell University Outline • Personal research in postpartum uterine disease of dairy cows • Reflections on research more generally • Production animal research • Research in veterinary practice • Academic practice • Private practice • The research imperative • For Society and the Profession • For Universities • For individuals Up to circa 1990 • Most agreed “endometritis” was bad for reproduction • Several disagreed • Miller HV, et al., Bov.Pract. 1980 • Griffin, Hartigan & Nunn, Theriogenology, 1974 a,b • Diagnosis • N. America: palpation and visible exudate • Incidence < 20 % • Europe: vaginoscopy • Incidence ~ 40 % Maurice E. “Pete” White Editor, Cornell Veterinarian Creator, “Consultant” Bovine Endometritis: The burden of proof. Cornell Vet., 1992 Endometrial cytology Endometrial cytology Endometritis • Cows at 40 – 60 days postpartum • End of voluntary waiting period • 5 dairy herds in Central New York • Endometrial cytology • No further involvement in management • Followed up via dairy records Endometritis Survival Analysis Effect of Endometritis at 7 weeks 1.0 Endometritis-negative Endometritis-positive 0.8 0.6 122 days 158 days P = 0.002 Proportion Open 0.4 30% censored 0.2 P = 0.003 18% censored 0.0 0 50 100 150 200 250 300 350 Time (Days) Some central questions • Which pathogens are primarily responsible for endometritis? • Which metabolic and immune factors mediate susceptibility to and pathogenesis of endometritis? • How does endometritis mediate infertility? Which pathogens cause endometritis? • Most cows have postpartum uterine bacterial infection • Only a subset develops disease • Extensively studied by conventional means • Mixed postpartum population initially judged to be insignificant (Griffin, Hartigan, Nunn, 1974) • Persistence of Trueperella pyogenes beyond 21 days detrimental to fertility • Synergistic action of T.
    [Show full text]
  • An Incomplete Bibliography of Publications in Historia Scientiarum (International Journal of the History of Science Society of Japan)
    An Incomplete Bibliography of Publications in Historia Scientiarum (International Journal of the History of Science Society of Japan) Nelson H. F. Beebe University of Utah Department of Mathematics, 110 LCB 155 S 1400 E RM 233 Salt Lake City, UT 84112-0090 USA Tel: +1 801 581 5254 FAX: +1 801 581 4148 E-mail: [email protected], [email protected], [email protected] (Internet) WWW URL: http://www.math.utah.edu/~beebe/ 27 December 2018 Version 1.03 Title word cross-reference $124.00 [Hij90]. $29.00 [Bur93a]. 3[+]1=8 [Hol03]. $49.95 [Yaj07]. 7 × 7 e `eme ieme th [Yam10]. 9 [Mur94]. [Gui86, Pen04, Yos81a]. [DP88].P [Ano94b]. ≈ n 2 2 [Pen04]. π [HKY89, Nak94a, Vol94]. π 3(1=8) [Mur92b]. i=1 xi = x [Ras94a]. × [Har87b]. 0 [Hig01a, Izu05, Miu03, Mor04b, Sat05, She06a, She06b]. 0-19-860665-6 [Sat05]. 0-19-927016-3 [Izu05]. 0-520-24607-1 [Yaj07]. 0-691-11445-5 [She06b]. 0-8018-8235-4 [She06a]. 0-86078-668-4 [Hig01a]. 000 [Sas81b]. 00FF [Yos82]. 02/06/2000 [Has01]. 1 [Kaw93a, Oka98, Yos98]. 10 [Høy03, Yos81c]. 10th [Suz81]. 11 [Hay94]. 12/02/1906 [Has01]. 1475/76 [Hig01b]. 1500 [Ito83]. 15073 [Mur05b]. 1 2 16th [Maa91]. 17 [Sat86, Sat87]. 1700 [Nak83]. 17th [Maa91, Oh14, Yin13]. 18.5cm [Har87b]. 1843 [Ito16]. 1847 [Nak00a]. 1847/48 [Nak00a]. 1880s [Kim08a]. 18th [Ano94b, Kaw11, Kob02, Lor86, Nag80, Oh14, Nak98, THI17]. 18th-century [Kob02]. 19 [Nis92]. 190F [Yos98]. 1920s [Bro07, Kan13, Kim08b]. 1930 [Yaj07]. 1930s [Bro89, Kan13]. 1940 [Fur97]. 1940s [Mat98, YW05]. 1950s [HR15, Yam09]. 1955 [Nis92]. 1960s [FH12].
    [Show full text]
  • WOMEN in STEM WORD SEARCH Learn About Women Scientists Who Broke MARY JACKSON Boundaries and Made Important Discoveries Credit: NASA
    WOMEN IN STEM WORD SEARCH Learn about women scientists who broke MARY JACKSON boundaries and made important discoveries Credit: NASA V WANGARIMAATHAIMEQNW QAWAZSXEDCFRVGHAITIA XMLONOSKCAJYRAMRRPLL ZAPELNMTIOPYBNMYUIKK ORBINJANEGOODALLCRNC NYDBATRKJLXDTOCEEAAO IGOAQSIDFYOWRNBAICRT KONGHJMNOQPEVAMKRHFN GLNZXCAVALNLLUQEAEDI DDABNMEWETRLYXKYMLNL OASPOIJUIIEFERLDSCIC HRTAZWEESKXRAEQTSALC YOREYAMTREPPEOGAIRAM HSIWEEIXRYATYSUJMSSA TSCESOSRAHYNMPHIKOOR OAKIDSOATGPMOERKINRA RVLFAPNRNRTUYOUYOUQB OWAERTEYMDGUOFXBCVOR DENXOBIVANDANASHIVAA MMDYLADDRANYAMEIRAMB Answer key on page 4 Alice Ball Mae Jemison Rachel Carson Barbara McClintock Marie Curie Rosalind Franklin Bertha Parker Marie Maynard Daly Tu Youyou Donna Strickland Maria Goeppert Mayer Valentina Tereshkova Dorothy Hodgkin Mary Golda Ross Vandana Shiva Jane Goodall Mary Jackson Wangari Maathai An agency of the Lise Meitner Mary Leakey Government of Ontario WOMEN IN STEM WORD SEARCH Learn about women scientists who broke MAE JEMISON boundaries and made important discoveries Credit: NASA 1. Marie Curie (1867-1934) Polish-born French physicist and chemist. She was the first woman to be awarded a Nobel Prize (Physics), in 1903, for her research on X-rays and radioactivity, and the first person to be awarded a second Nobel Prize (Chemistry), in 1911, for her discovery of the elements polonium and radium. 2. Lise Meitner (1878-1968) Austrian-born nuclear physicist. Her research led to the discovery of uranium fission, for which only her male colleague, Otto Hahn, was awarded the Nobel Prize in 1945. 1n 1997, an element was named meitnerium (Mt) in her honour. 3. Alice Ball (1892-1916) Black American chemist. She developed the first effective treatment for leprosy, later known as the Ball Method, which was widely used for over thirty years until the introduction of sulfone drugs. 4. Maria Goeppert Mayer (1906-1972) German-born American mathematician and physicist.
    [Show full text]
  • KITCHEN CHEMISTRY Bijeta Roynath & Prasanta Kumar Sahoo
    Test Your Knowledge KITCHEN CHEMISTRY Bijeta Roynath & Prasanta Kumar Sahoo 1. The common cooking fuel, Liquefied Petroleum Gas 10. Which of the following could be produced by the gas (LPG), is a mixture of two hydrocarbons. These are: stove? (a) Methane and Butane (b) Propane and Butane (a) Nitrogen Oxides (b) Sulphur dioxides (c) Oxygen and Hydrogen (d) Hexane and Propane (c) Carbon monoxide (d) Dihydrogen oxide 2. Hydrocarbons in LPG are colourless and odourless. 11. Which of the following chemical is found in dish- Therefore, a strong smelling agent added to LPG washing detergent? cylinders to detect leakage is: (a) Carbon monoxide (b) Chlorine (a) Ethyl mercaptan (b) Nitrous oxide (c) Sulphur dioxide (d) Lithium (c) Hydrogen sulfide (d) Chloroform 12. Proteins help build our body and carbohydrates 3. Chemical irritant produced during chopping an provide energy to the body. The protein and onion (Allium cepa) which makes our eye weepy is: carbohydrate found in milk are: (a) Allinase (b) Sulfoxide (a) Albumin and maltose (b) Pepsin and sucrose (c) Syn-propanethial-S-oxide (d) Allyl mercaptan (c) Collagen and fructose (d) Casein and lactose 4. The powerful anti-inflammatory and antioxidant 13. Salt readily absorbs water from the surroundings. properties of haldi or turmeric (Curcuma longa) are Sprinkling salt on salad releases water from it after due to presence of: few seconds. The process is: (a) Curcumin (b) Gingerol (a) Osmosis (b) Adsorption (c) Cymene (d) Capsaicin (c) Dehydration (d) Oxidation 5. The active ingredient in chilli peppers (Capsicum) 14. Washing hands before eating prevents illness which produces heat and burning sensation in the by killing germs.
    [Show full text]
  • Research Organizations and Major Discoveries in Twentieth-Century Science: a Case Study of Excellence in Biomedical Research
    A Service of Leibniz-Informationszentrum econstor Wirtschaft Leibniz Information Centre Make Your Publications Visible. zbw for Economics Hollingsworth, Joseph Rogers Working Paper Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research WZB Discussion Paper, No. P 02-003 Provided in Cooperation with: WZB Berlin Social Science Center Suggested Citation: Hollingsworth, Joseph Rogers (2002) : Research organizations and major discoveries in twentieth-century science: A case study of excellence in biomedical research, WZB Discussion Paper, No. P 02-003, Wissenschaftszentrum Berlin für Sozialforschung (WZB), Berlin This Version is available at: http://hdl.handle.net/10419/50229 Standard-Nutzungsbedingungen: Terms of use: Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Documents in EconStor may be saved and copied for your Zwecken und zum Privatgebrauch gespeichert und kopiert werden. personal and scholarly purposes. Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle You are not to copy documents for public or commercial Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich purposes, to exhibit the documents publicly, to make them machen, vertreiben oder anderweitig nutzen. publicly available on the internet, or to distribute or otherwise use the documents in public. Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, If the documents have been made available under an Open gelten abweichend von diesen Nutzungsbedingungen die in der dort Content Licence (especially Creative Commons Licences), you genannten Lizenz gewährten Nutzungsrechte. may exercise further usage rights as specified in the indicated licence. www.econstor.eu P 02 – 003 RESEARCH ORGANIZATIONS AND MAJOR DISCOVERIES IN TWENTIETH-CENTURY SCIENCE: A CASE STUDY OF EXCELLENCE IN BIOMEDICAL RESEARCH J.
    [Show full text]