BBSRC support for Industrial and Bioenergy

Dr Colin Miles What is UK Research and Innovation (UKRI) ?

• UKRI is the new funding organisation for research and innovation in the UK.

• UK Research and Innovation launched in April 2018.

• UKRI comprises seven UK research councils, Innovate UK and a new organisation, Research , working closely with its partners in the devolved administrations UKRI Strategic Prospectus : Objectives

UKRI objectives:

− Pushing the frontiers of human knowledge − Delivering economic impact and prosperity − Creating social and cultural impact − Providing the best foundation and environment for research and innovation − Delivering and being accountable as an outstanding organisation

What does BBSRC do ?

Invests in world- Invests in class bioscience bioscience training research in UK & skills for the next Universities & generation of Institutes bioscientists

Drives the widest possible social & Promotes public economic impact dialogue on from our bioscience bioscience BBSRC Forward Look for UK Bioscience

Advancing the frontiers of bioscience discovery

Understanding Transformative the rules of life technologies

Tackling strategic challenges Bioscience for Bioscience for Bioscience for renewable an integrated sustainable resources and understanding agriculture and food clean growth of health

Building strong foundations Collaboration, People Infrastructure partnerships and talent and KE BBSRC Vision and Strategy: IBBE (2013-16) VISION:

UK bioscience research delivering new products and processes for manufacturing in the Bioeconomy, driving economic growth in the UK and worldwide.

STRATEGY:

Public Policy

International Funders Innovate UK BBSRC PoC Funds Research NIBB BIVs Councils

IB Catalyst Commercialisation Scale-up & Demonstration 13 BBSRC Networks in IB Catalyst Industrial Biotechnology & Funding programme involving Bioenergy BBSRC, EPSRC, Innovate UK £18M funding for 2014-19 £76M funding for 2014-16 BBSRC NIBB (2014-2019)

Biorefining

Bioprocessing Novel Chassis HVC/Natural Products

Biocatalysis Cross Cutting

www.bbsrc.ac.uk/bbsrcnib | [email protected]

BBSRC NIBB: Growing the UK IBBE Community 2014-2019

3020+ UK academic members @ 140+ UK institutions

UK plc across supply & value chains 820+ [micro-SMEs to multinationals]u

115+ UK community-led meetings

£12.9M invested in pump-priming projects + £ 37% industrial contributions

Based on data collection up to January 2018 UKRI investments in Synthetic

BrisSynBio – Bristol Led by: Professor Dek Woolfson,

SBRC Nottingham Led by: Professor Nigel Minton, The University of Nottingham

OpenPlant – Cambridge and John Innes Centre Led by: Professor , and Professor Dale Sanders, John Innes Centre WISB – Warwick Led by: Professor John McCarthy, The University of Warwick

SYNBIOCHEM – Manchester Led by: Professor Nigel Scrutton, The University of Manchester

UK Centre for Mammalian Research – Edinburgh Led by: Professor Susan Rosser, The University of Edinburgh

Successes…….. High Value Chemicals from Unavoidable Food Waste

Frontiers of Knowledge Economy

Orange pulp waste Grapefruit flavour £ Society (2009) (2017) GREEN BIOLOGICS AND CHEMICALS FROM WASTE

IB Catalyst Round 1: CLEAVE technology for Clostridium strain development.

BBSRC NIBB BIV/PoC and IB Catalyst Round 4: overcoming solventogenic stress resulting in more efficient production.

• GreenFlame: pure n-Butanol (Consumer product)

• Beauty Secrets: pure Acetone (Personal care product)

• Xylitol food and personal care product Policy Impacts from BBSRC NIBB 2014-2019

Feedstock transitions 2020-2050 Feedstock Transitions 2020-2050 Next steps……. BBSRC Vision and Strategy for IBBE (2019-2024) VISION:

UK bioscience research delivering new products and processes for sustainable manufacturing in the Bioeconomy, driving economic growth in the UK and worldwide.

STRATEGY:

Public Policy

International Funders/ EU Innovate UK BBSRC PoC Funds Research NIBB BIVs Councils

Global Commercialisation Challenges Funds Scale-up & Demonstration

6 BBSRC Networks in Global Challenges and Newton Industrial Biotechnology & Fund Bioenergy 3 year funding programmes £11M funding for 2019-2014 Currently including BBSRC, EPSRC, Innovate UK £15M funding for 2019-22 Six new Networks (2019-2024)……

Algae-UK: Exploiting the algal treasure trove Professor Saul Purton University College, London

Biomass Biorefinery Network (BBNet) Professor Simon McQueen Mason,

Carbon Recycling: Converting waste derived GHG into chemicals, fuels and animal feed (CCNet) Professor Nigel Minton, University of Nottingham

Elements of Bioremediation, Biomanufacturing & Bioenergy (E3B): Professor Nigel Robinson, Durham University

Environmental Biotechnology Network (EBNet) Professor Sonia Heaven, University of Southampton

High Value Biorenewables (HVB) Network Professor Ian Graham, University of York

What are the options for future developments?

• Global Challenges Research Fund (from 2020 onwards). • Newton Fund: Partnership (from 2020 onwards). • UKRI Future Leader Fellowships. • Further links through (eg) BBNet and BBSRC International Partnership funding. BBSRC support for Industrial Biotechnology and Bioenergy

Questions? Newton-Bhabha Fund: Industrial Waste Challenge • Collaborative activity to use cutting-edge solutions to reduce industrial waste in India launched in 2017.

• Projects to address reducing industrial waste and the valorisation of waste using biotechnology in one or more of these 5 sectors:

1. Leather/tanning/textiles 2. Municipal solid waste 3. Paper and pulp 4. Sewage 5. Sugar cane

• Open to both academic and business-led consortia

Newton-Bhabha UK-India Industrial Waste 2018-2021

Proposal Priority area Lead India Partner

Economic non-food sugar from variable Municipal solid waste University of Leeds Institute of Chemical mixed solid waste for high value Technology (ICT) chemical products Mumbai

Valorising Waste from Sugar Cane and Sugarcane Queen's University Vasantdada Sugar Associated Industries via Innovations in Belfast Institute Pre-treatment, Biotransformation and Process Intensification

BIOREVIEW: Biorefining Value from Sugarcane Aberystwyth University CSIR-Indian Institute of Industrial Waste Chemical Technology,

Integrated biorefinery for converting Paper/pulp The University of CSIR - Indian Institute paper mill waste into chemical wealth Manchester of Petroleum (waste-2-wealth)

Reducing industrial waste from Sugarcane University of York International Center for sugarcane processing in India Genetic Engineering and Biotechnology New Generation of Bioplastics from Agricultural Residues (Lignin) Frontiers of Knowledge Economy Society

Aromatic feedstock chemicals for Durable plastics generated polymerisation from waste 2015 2017