Program Book

The Genetics Society of America Conferences

55th Annual Drosophila Research Conference March 26–30, 2014 • San Diego, CA PROGRAM GUIDE

2014 Drosophila Program Cover.indd 1 1/21/14 11:33 AM

Meeting Organizers

Daniela Drummond-Barbosa, Johns Hopkins University Elissa Lei, NIH/National Institute of Diabetes and Digestive and Kidney Diseases Mihaela Serpe, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development Mark Van Doren, Johns Hopkins University

Drosophila Board of Directors

Officers President Amy Bejsovec President-Elect 2014 Ken Irvine President-Elect 2015 David Bilder Past-President 2012 Michael O’Connor Past-President 2011 Liz Gavis & Elections Chair Treasurer Deborah Andrew

Regional Representatives International Representatives

Canada Laura Nilson Australia/Oceana Gary Hime Great Lakes Helen Salz Asia Shigeo Hiyashi Northwest Leo Pallanck Europe Daniel St. Johnston Southeast Steve Crews Latin America Mariana Melani California Angelika Stathopoulos Heartland Giovanni Bosco Primary Undergraduate Institution New England Eric Baehrecke Representative Mid-Atlantic Jessica Triesman Midwest Seth Blair Alexis Nagengast

Sponsored by: The Genetics Society of America 9650 Rockville Pike, Bethesda, Maryland 20814-3998 Telephone: (301) 634-7300 • Fax: (301) 634-7079 E-mail: [email protected] • Web site: genetics-gsa.org Conference Web site: genetics-gsa.org/drosophila/2014

Table of Contents

Schedule of Events ...... 3 Town & Country Resort & Conference Center Map ...... 8 General Information ...... 9 Education Opportunities ...... 11 Awards Larry Sandler Memorial Lecture ...... 12 The Victoria Finnerty Memorial Fund for Undergraduate Travel Award ...... 12 The DeLill Nasser Award for Professional Development in Genetics ...... 13 Poster Award Competition ...... 13 Sponsors & Exhibitors ...... 14 Posters and Exhibits Map ...... 19 Opening General Session and Plenary Sessions ...... 20 Workshops ...... 22 Concurrent Platform Sessions ...... 28 Poster Sessions ...... 42 Speaker and Author Index ...... 81 Keyword Index ...... 104 Flybase Genetic Index to Abstracts ...... 109

Future Meeting Dates

2015 2016 2017 2018 March 4-8 July 13-17 March 29-April 2 April 11-15 Chicago, IL Orlando, FL San Diego, CA Philadelphia, PA

SCHEDULE OF EVENTS

WEDNESDAY, March 26

11:00 am - 5:00 pm GSA Trainee Boot Camp Royal Palm Ballroom 4 Additional registration required 12:00 noon - 6:00 pm Ecdysone Workshop Pacific Ballroom Salon 3 Organizers: Ginger Carney, Texas A & M University; and Laurie von Kalm, University of Central Florida 3:00 pm - 6:30 pm Speaker Ready Room Terrace Salon 3 3:00 pm - 6:00 pm Drosophila Board of Directors Meeting Pacific Ballroom Salon 1 3:30 pm - 9:00 pm Registration and Book/T-Shirt Pick Up Open Atlas Foyer 5:00 pm - 7:00 pm GSA Special Interest Group Mixer Royal Palm Ballroom 5-6 5:00 pm - 12:00 am Posters Open Grand Exhibit Hall 7:00 pm - 9:15 pm Opening General Session Atlas Ballroom Moderators: Mark Van Doren, Johns Hopkins University, Baltimore, Maryland; and Elissa Lei, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 7:00 pm Welcome and Opening Remarks Mark Van Doren, Johns Hopkins University, Baltimore, Maryland 7:10 pm GSA Welcome and Update Adam Fagen, Genetics Society of America, Bethesda, Maryland 7:20 pm Larry Sandler Awardee Introduction Mark Van Doren, Johns Hopkins University, Baltimore, Maryland 7:25 pm Larry Sandler Lecture 7:55 pm Keynote Introduction Elissa Lei, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 8:00 pm Science, Biology, and the World’s Future Bruce Alberts, UCSF, San Francisco, CA 9:00 pm Presentation of George W. Beadle Award to Hugo Bellen, Baylor College of Medicine/HHMI 9:00 pm – 11:00 pm Mixer/Reception Grand Plaza Sponsored by the journals GENETICS and G3: Genes|Genomes|Genetics

SCHEDULE OF EVENTS

THURSDAY, March 27 12:01 am - 12:00 am Posters Open Grand Exhibit Hall 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 7:15 am - 8:30 am How To Get Published Breakfast Golden Pacific Ballroom Ticket required 7:15 am - 8:30 am Continental Breakfast Atlas Foyer 8:00 am - 5:00 pm Registration and Book/T-Shirt Pick Up Open Atlas Foyer 8:30 am - 12:00 noon Plenary Session I Atlas Ballroom Moderator: Daniela Drummond-Barbosa, Johns Hopkins University, Baltimore, Maryland 8:30 am Image Award Presentation David Bilder, University of California, Berkeley 8:35 am Controlling Morphogen Gradients Arthur D. Lander, Dept Dev Cell Biol and Dept of Biomedical Engineering, Univ California, Irvine, Irvine, CA 9:05 am Fat Cadherins in Growth, Planar Polarity and Mitochondrial Activity Helen McNeill, Lunenfeld-Tanenbaum Institute, Mt Sinai Hospital, Toronto, ON, Canada; Dept. Molecular Genetics, University of Toronto Toronto, Canada 9:35 am Epigenetic Regulation of Drosophila Male Germ Cell Differentiation Xin Chen, Dept Biol, Johns Hopkins Univ, Baltimore, MD 10:05 am Break 10:30 am X marks the spot: Targeting the X Chromosome During Dosage Compensation Erica N. Larschan, Molec Biol, Cellular Biol & Biochem, Brown Univ, Providence, RI 11:00 am Circuit Mechanisms Underlying Behavioral Decisions and Motor Program Sequencing in Ecdysis Benjamin H. White, Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD 11:30 am The Molecular Evolution of Morphology and Behavior David L. Stern, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA 8:30 am - 12:30 pm The Genetics Conference Experience Pacific Ballroom Salon 2 By invitation 12:45 pm - 2:00 pm GSA Career Luncheon Royal Palm Ballroom 4 Ticket required 1:00 pm - 5:00 pm FlyBase & Galaxy Demo Room Open for Tutorials & Royal Palm Ballroom 1-3 Discussions Presentations: 2:00-2:15 pm: Human Health Related models in Drosophila 2:20-2:35 pm: Using and Querying high throughput data 2:40-2:55 pm: Galaxy toolset for Drosophila genomics 2:00 pm - 4:00 pm Exhibits Open & Poster Presentations Grand Exhibit Hall 4:30 pm - 6:30 pm Concurrent Platform Sessions

Cell Division & Growth Control Town & Country Neural Development Golden West Organogenesis & Gametogenesis California 6:30 pm - 8:00 pm Undergrad Mixer Tiki Pavilion 8:00 pm - 11:00 pm Exhibits Open & Poster Viewing Grand Exhibit Hall

SCHEDULE OF EVENTS

FRIDAY, March 28 12:01 am - 12:00 am Posters Open Grand Exhibit Hall 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 8:15 am - 5:00 pm Registration and Book/T-Shirt Pick Up Open Atlas Foyer 8:30 am - 10:15 am Concurrent Platform Sessions

Cell Cycle & Cell Death Town & Country Evolution & Quantitative Genetics I Golden West Pattern Formation California 10:15 am - 10:45 am Break Atlas Foyer 10:45 am - 12:30 pm Concurrent Platform Session

Cell Biology & Cytoskeleton Town & Country Evolution & Quantitative Genetics II Golden West Chromatin & Epigenetics California 12:45 pm - 1:45 pm GSA Advocacy Lunch Royal Palm Ballroom 4 Ticket required 1:00 pm - 6:00 pm FlyBase & Galaxy Demo Room Open for Tutorials & Royal Palm Ballroom 1-3 Discussions Presentations: 3:15-3:30 pm: Human Health Related models in Drosophila 3:35-3:50 pm: Using and Querying high throughput data 3:55-4:10 pm: Galaxy toolset for Drosophila genomics 1:30 pm - 4:00 pm Undergraduate Plenary Session and Workshop Royal Palm Ballroom 5-6 Organizers: Alexis Nagengast, Widener University; and Beth Ruedi, Genetics Society of America, Bethesda, Maryland 1:45 pm - 3:45 pm Concurrent Workshops

Flies on Drugs - Screening for Therapeutics in Drosophila Pacific Ballroom Salons Organizers: Daniela Zarnescu, University of Arizona, Tucson; 4-5 and Tin Tin Su, University of Colorado, Boulder Developmental Mechanics Pacific Ballroom Salon 3 Organizers: Guy Tanentzapf, University of British Columbia, Vancouver Canada; and Rodrigo Fernandez-Gonzalez, University of Toronto, Canada Drosophila Male Fertility as a Cell Biological Model Pacific Ballroom Salon 7 Organizers: Julie Brill, The Hospital for Sick Children, Toronto, Canada; and Mariana Wolfner, Cornell University, Ithaca, New York The Practice and Promise of CRISPR/Cas9-mediated Pacific Ballroom Salon 1 Genome Engineering Organizers: Melissa Harrison, University of Wisconsin, Madison; Kate O'Connor-Giles, University of Wisconsin, Madison; and Jill Wildonger, University of Wisconsin, Madison Extracellular Epithelial Barriers Pacific Salon 6 Organizers: Edward Blumenthal, Marquette University, Milwaukee, Wisconsin; and Bernard Moussian, University of Tuebingen, Germany 2:00 pm - 4:00 pm Dedicated Exhibit Time Grand Exhibit Hall 4:30 pm - 6:30 pm Concurrent Platform Sessions

Physiology, Organismal Growth & Aging Town & Country Techniques & Resources Golden West RNA Biology California 8:00 pm - 11:00 pm Exhibits Open & Poster Presentations Grand Exhibit Hall

SCHEDULE OF EVENTS

SATURDAY, March 29 12:01 am - 10:00 pm Posters Open Grand Exhibit Hall 7:00 am - 3:00 pm Speaker Ready Room Terrace Salon 3 8:15 am - 3:00 pm Registration and Book/T-Shirt Pick Up Open Atlas Foyer 8:30 am - 10:15 am Concurrent Platform Sessions Cell Biology & Signal Transduction Town & Country Drosophila Models of Human Disease I Golden West Regulation of Gene Expression I California 10:15 am - 10:45 am Break Atlas Foyer 10:45 am - 12:30 pm Concurrent Platform Sessions Organelles & Trafficking Town & Country Drosophila Models of Human Disease II Golden West Gene Expression & Chromatin II California 1:30 pm - 3:30 pm Exhibits Open & Poster Presentations Grand Exhibit Hall 4:00 pm - 6:00 pm Concurrent Platform Sessions

Immunity & Pathogenesis Town & Country Neurophysiology & Behavior Golden West Stem Cells California 6:45 pm - 8:45 pm Concurrent Workshops

Drosophila Metabolomics Workshop Golden Pacific Ballroom Organizers: Thomas Merritt, Laurentian University, Sudbury, Canada; Daniel Promislow, University of Washington, Seattle; and Jason Tennessen, Indiana University, Bloomington Wound Healing and Regeneration Pacific Ballroom Salon 3 Organizers: Adrian Halme, University of Virginia School of Medicine, Charlottesville; and Rachel Smith-Bolton, University of Illinois, Urbana-Champaign Data-driven Mathematical Modeling in Drosophila as a Pacific Ballroom Salon 7 Tool for Discovery Organizer: David M Umulis, Purdue University, West Lafayette, Indiana Drosophila Research and Pedagogy at Primarily Pacific Ballroom Salons 4-5 Undergraduate Institutions (PUI) Organizers: Scott Ferguson, SUNY, Fredonia, New York; Jennifer Kennell, Vassar College, Poughkeepsie, New York; David M Roberts, Franklin & Marshall College, Lancaster, PA; and Josefa Steinhauer, Yeshiva University, New York Genetic, Genomic & Informatic Resources for Non- Pacific Ballroom Salon 1 melanogaster Drosophilidae Organizers: William Gelbart, Harvard University, Cambridge, Massachusetts; and Therese Markow, University of California, San Diego 7:00 pm - 10:00 pm Exhibits Open & Poster Viewing Grand Exhibit Hall 9:15 pm - 11:15 pm Concurrent Workshops

Everything You Ever Wanted to Know About Sex Pacific Ballroom Salon 3 Organizers: Artyom Kopp, University of California, Davis; and Michelle Arbeitman, Florida State University, Tallahassee Feeding Behavior, Nutrition and Metabolism Golden Pacific Ballroom Organizers: Tânia Reis, University of Colorado School of Medicine, Aurora; and William W Ja, The Scripps Research Institute, Jupiter, Florida Centrosomes and Cilia in Cell Division and Disease Pacific Ballroom Salon 7 Organizers: Tim Megraw, Florida State University, Tallahassee; and Tomer Avidor-Reiss, University of Toledo, Ohio 6

SCHEDULE OF EVENTS

SUNDAY, March 30 8:30 am - 12:00 noon Plenary Session II Atlas Ballroom Moderator: Mihaela Serpe, NIH/National Institute of Child Health and Human Development, Bethesda, Maryland 8:30 am Poster Award Presentation Mihaela Serpe, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland 8:35 am Charting the Genotype-Phenotype Map: Lessons from Drosophila Trudy F. Mackay, Dept Biological Sciences, North Carolina State Univ, Raleigh, NC 9:05 am Walking the Highwire from Synaptic Growth to the Axon Injury Response Pathway Aaron DiAntonio, Dept of Developmental Biology, Washington University School of Medicine, St. Louis, MO 9:35 am piRNAs Function for the Safeguard of Germline Genome Toshie Kai, Temasek Lifesciences Laboratory/Dept. Biological Science, National University of Singapore, Singapore 10:05 am Break 10:30 am Multiple Layers of Complexity in the Regulation of the Bithorax Complex Francois Karch, Dept Genetic and Evolution, Univ Geneva, Geneva, Switzerland 11:00 am Cardiomyopathy Models Rolf Bodmer, Development and Agi, Sanford-Burnham Medical Research Institute, La Jolla, CA 11:30 am The Conflicted Existence of the Mitochondrial Genome Patrick H. O'Farrell, Dept Biochemistry, Univ California, San Francisco, CA

RESORT MAP

GENERAL INFORMATION

 Badges Badges are required for admission to all sessions, the opening mixer, and the posters and exhibits in the Grand Exhibit Hall. Security officers will not allow individuals without badges to enter the Grand Exhibit Hall. If you lose your badge, a replacement may be requested at the Registration and Information Counters during posted registration hours. Badges may not be used by anyone other than the registered attendee. Each attendee must have his/her own badge.

 Employment Opportunities/Seeking Employment Notices – Convention Registration Desk, Atlas Foyer Individuals and institutions offering or seeking employment may post notices and résumés on the "Employment Opportunities" bulletin boards set up near the Registration and Information Counters at the Convention Registration Desk. Be sure to stop by the GSA Booth and ask about the new Jobs Board now online at www.geneticscareers.org

 FlyBase Demonstrations – Royal Palms Salons 1-3 FlyBase and Galaxy (galaxyproject.org ) jointly invite all Conference registrants to come to the demo room to learn how to make the best use of the new FlyBase & Galaxy tools and features for your research and teaching. Throughout the afternoon, other than the scheduled group presentations noted below, FlyBase & Galaxy personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions. Any thoughts on improvements we can make to FlyBase are gratefully appreciated.

Thursday 1:00pm - 5:00pm Demo room open for tutorials and discussions

Presentations: 2:00pm-2:15pm: "Human health related models in Drosophila" 2:20pm-2:35pm: "Using and querying high throughput data" 2:40pm-2:55pm: “Galaxy toolset for Drosophila genomics Friday 1:00pm - 6:00pm Demo room open for tutorials and discussions

Presentations: 3:45pm-4:00pm: "Human health related models in Drosophila" 4:05pm-4:20pm: "Using and querying high throughput data" 4:25pm-4:40pm: “Galaxy toolset for Drosophila genomics

 Internet Access – Conference Center Complimentary high speed internet access is available in the Atlas Ballroom foyer.

 Meals Please note that two meals are included in the meeting registration: the Opening Mixer on Wednesday night (with heavy hors d’oeuvres and a cash bar) and the Continental Breakfast on Thursday morning. All other meals are not included in your conference registration. For all other meals you may choose from options within the hotel (including grab and go food kiosks located in the meeting area for breakfast and lunch) or at nearby locations. Fashion Valley Shopping Center is conveniently located via footbridge behind the Royal Palm Tower and features fast-food and a variety of restaurants.

 Message Boards – Convention Registration Area Message boards will be located near the Registration and Information Counters.

 Parking Parking is available at the Town & Country Resort & Conference Center at a rate of $10 per with in/out privileges.

 Photography Absolutely no photography is allowed in the exhibit hall/poster display areas.

 Poster Sessions and Exhibits – Grand Exhibit Hall All posters will be displayed in the Grand Exhibit Hall. The Hall will be open to Conference registrants on a 24-hour basis beginning at 5:00 pm, Wednesday, March 26, until 10:00 pm, Saturday, March 29. Security will be posted at the entrance to the Hall and only individuals with official Drosophila Conference registration badges will be admitted. All attendees are responsible for their own personal items and should not leave things unattended. Guest pass applications may be made at the registration counter during regular registration hours.

GENERAL INFORMATION

Exhibit representatives will be in their booths: Thursday, March 27: 2:00 pm–4:00 pm and 8:00 pm–11:00 pm Friday, March 28: 2:00 pm–4:00 pm and 8:00 pm–11:00 pm Saturday, March 29: 1:30 pm–3:30 pm and 7:00 pm–10:00 pm

Authors are expected to be present at their boards according to the following schedule: Thursday, March 27: 2:00 pm–3:00 pm Even-Numbered Posters 3:00 pm–4:00 pm Odd-Numbered Posters 8:00 pm–11:00 pm Open poster viewing (Authors not required to be present)

Friday, March 28 2:00 pm–4:00 pm Open poster viewing (Authors not required to be present) 8:00 pm–9:00 pm “C” posters 9:00 pm–10:00 pm “B” posters 10:00 pm–11:00 pm “A” posters

Saturday, March 29: 1:30 pm-2:30 pm Odd-Numbered Posters 2:30 pm-3:30 pm Even-Numbered Posters 7:00 pm–10:00 pm Open poster viewing (Authors not required to be present)

All posters must be removed from poster boards no later than 11:00 pm on Saturday, March 29. After that time, remaining posters will be removed by vendors and may be lost or thrown away. The GSA Administrative Office does not take responsibility for posters that are not removed by 11:00 pm on Saturday.

 Registration, Book and T-Shirt Pickup – Ballroom Foyer Conference registration and book pickup will be open as follows: Wednesday, March 26 3:30 pm–9:00 pm Thursday, March 27 8:00 am–5:00 pm Friday, March 28 8:30 am–5:00 pm Saturday, March 29 8:30 am–3:00 pm

Note that attendees must be registered before attending the Opening General Session on Wednesday, March 26, 7:00 pm in order to attend that session.

Those who purchased t-shirts can pick them up at any time during normal registration hours but BEFORE noon on March 29. A limited number of additional t-shirts have been ordered and will be available for sale onsite.

 Speaker Ready Room – Terrace Salon 3 All Speakers are required to load and check their presentation at least four hours (preferably the day before) in advance of the start of the session (not your specific time slot but the overall session time) in the Speaker Ready Room. Here is a schedule of the times that the Speaker Ready Room will be open:

Wednesday, March 26 3:00 pm-6:30 pm Thursday, March 27 7:00 am-3:00 pm Friday, March 28 7:00 am-3:00 pm Saturday, March 29 7:00 am-3:00 pm

IMPORTANT – Even if you have loaded your presentation before the conference you still must check in at the Speaker Ready Room. Presentations cannot be loaded in the meeting rooms.

EDUCATION OPPORTUNITIES

GSA is actively expanding our educational programming, which includes a web portal for peer-reviewed genetics education resources, career development programs for trainees, workshops, and much more. Part of this education initiative is developing a consistent set of educational programs for all GSA conferences. Currently, the infrastructure of the programming includes programs for undergraduate researchers; graduate student and postdoctoral trainees; genetics students at local undergraduate institutions; and genetics educators.

Wednesday, March 26 11:00 am-5:00 pm: GSA Trainee Boot Camp (advanced registration required) - Royal Palm Salon 4 Open to Grad students and Postdocs only Based on feedback from trainees both in focus groups and individual conversations, GSA is hosting a pre-conference “bootcamp” with a series of professional development workshops. Advance registration required.

5:00-7:00 pm: GSA Education Special Interest Group Mixer/Pedagogy Workshop – Royal Palm Salon 5-6 Faculty with a passion for genetics education are encouraged to attend this mixer, where they can mix and mingle with other educators. Current members of the Education SIG can catch up on actions taken by GSA with regards to the education initiative, and those who are not yet SIG members can learn about the Education SIG. Information about GSA PREP, the Primers in GENETICS, and other education-related opportunities will also be discussed. From 6:00-7:00, we will have a workshop with four 15-minute presentations focused on pedagogy and best practices in education.

Thursday, March 27 8:30 am – 12:30 pm: “The Genetics Conference Experience” – Pacific Salon 2 Invitation Only The GSA Genetics Conference Experience provides students from genetics classes at local undergraduate institutions with the unique opportunity to observe distinguished career scientists present their current research in a conference setting. The students, accompanied by their professor, will receive a background lecture and participate in an interactive discussion before attending part of a plenary session. This informative and engaging program is meant to give students a glimpse into the real world of genetic research, and is NOT intended for students who are already involved in scientific research, but rather will provide students with the opportunity to learn about current scientific research outside of a textbook, witness the communication of scientific research first-hand, and ideally will foster an interest in furthering their science education.

12:45-2:00 pm: GSA Career Luncheon – Pacific Salon 3 The GSA Career Luncheon is an excellent opportunity for undergraduates, graduate students, and postdoctoral fellows to have informal conversations with senior career scientists regarding the unique challenges and rewards of a scientific career. The luncheon is organized by topic table. Topics may include things like: transition to independence, work-family balance, teaching at undergraduate institutions, careers outside traditional academia, the job search, the postdoc search, choosing the right graduate advisor, etc.

6:30-8:00 pm: Undergraduate Mixer – Tiki Pavilion Undergraduate researchers attending the conference will network on their own, forming a peer-group that will help provide lasting support for the remainder of the conference. Advance registration required.

Friday, March 28 1:30 – 4:00 pm: Plenary Session and Workshop for Undergraduate Researchers – Royal Palm Ballroom 5/6 Undergraduate conference attendees will attend an “Undergraduate Plenary Session” from 1:30-2:45 pm, with two talks presented at a level appropriate for an undergraduate audience. From 3:00-4:00 pm, undergraduates will have a chance to talk to a panel of graduate students about applications, interviewing, admission, choosing a lab, and quality of life in graduate school.

Saturday, March 29 6:45 – 8:45 pm: Drosophila Research and Pedagogy at Primarily Undergraduate Institutions (PUI) – Pacific Salon 4/5 This workshop focuses on increasing the quality and visibility of Drosophila research performed at primarily undergraduate institutions (PUIs) and facilitating faculty and students in these endeavors. The goals include: 1) Encouraging undergraduate research by providing a forum for students to make oral presentations; 2) Connecting people interested in this career path with current PUI faculty; 3) Establishing a network among current PUI faculty to promote discussion and provide support on professional issues that differ from those at large institutions; 4) Sharing concepts and techniques that encourage the integration of Drosophila as a teaching tool in the classroom and laboratory.

AWARDS

Larry Sandler Memorial Lecture

The Larry Sandler Memorial Lecture was established in 1988 by the colleagues, friends and students of Dr. Larry Sandler after his untimely death in February 1987. The award serves to honor Dr. Sandler for his many contributions to Drosophila genetics and his exceptional dedication to the training of Drosophila biologists. Any student completing his Ph.D. in an area of Drosophila research in the calendar year preceding the annual Drosophila Research Conference is eligible and may be nominated by his/her dissertation advisor. The Selection Committee for 2014 includes Chair, Marc Freeman, and committee, Erika Bach, Mike Buszczak, Sara Cherry, and Harmit Malik. The Committee reviews nominations, reads the dissertations of the finalists, and selects the awardee.

Past recipients of this honor are:

Bruce Edgar, 1988 James Wilhelm, 2001 Kate Harding, 1989 Matthew C. Gibson, 2002 Michael Dickinson, 1990 Sinisa Urban, 2003 Maurice Kernan, 1991 Sean McGuire, 2004 Doug Kellogg, 1992 Elissa Hallem, 2005 David Schneider, 1993 Daniel Ortiz-Barrientos, 2006 Kendal Broadie, 1994 Yu-Chiun Wang, 2007 David Begun, 1995 Adam A. L. Friedman, 2008 Chaoyong Ma, 1996 Timothy Weil, 2009 Abby Dernburg, 1997 Leonardo Barbosa Koerich, 2010 Nir Hacohen, 1998 Daniel Babcock, 2011 Terence Murphy, 1999 Stephanie Chen, 2012 Bin Chen, 2000 Weizhe Hong, 2013

The Victoria Finnerty Memorial Fund for Undergraduate Travel Award

This fund, which honors the memory of Victoria Finnerty, has been established to support travel costs for undergraduates engaged in research to attend the Annual Drosophila Research Conference. Vickie, who died in February 2011, was a long- time member of the Genetics Society of America and served the Drosophila community and the Genetics community at large in many capacities.

A wonderful geneticist, Vickie’s ground-breaking work as a graduate student used high resolution recombination analysis to dissect gene structure. This set the stage for a 35 year career in which she excelled as a gifted teacher as well as research scientist.

Congratulations to this year’s winners:

Daniel A. Friedman, Univ of California, Davis AnnJosette Ramirez, Arcadia Univ Nancy J. Levansailor, SUNY - Fredonia Zachary L. Sebo, Univ of Missouri - Kansas City Katharine Majeski, Kennesaw State Univ Letitia Thompson, The College of New Jersey Aidan L. McParland, Univ of New England Daniel M. Wong, Univ of California, Los Angeles Marvin Nayan, Univ of Washington Chenling Xu, Univ of California, Davis Trung T. Phan, Univ of Washington

To make a tax deductible contribution, send your check to the attention of Adam Fagen, Executive Director, The Genetics Society of America, 9650 Rockville Pike, Bethesda, MD 20814-3998. Please write “Finnerty Fund” in the memo portion of the check. Or you can make an online donation by visiting www.genetics-gsa.org.

AWARDS

The DeLill Nasser Award for Professional Development in Genetics

The DeLill Nasser Award for Professional Development in Genetics was established by The Genetics Society of America in mid-2001 in honor of the late DeLill Nasser, who served for 22 years as the program director of the Eukaryotic Genetics Section at the National Science Foundation.

The award fund, made possible by contributions from her family and friends. It recognizes Dr. Nasser’s contributions to the field of genetics and her strong support of young scientists. Travel and tuition awards will be made annually to allow graduate students and postdoctoral trainees to attend meetings or enroll in laboratory courses.

So far this year 11 awards were given, four of which were used to attend the Drosophila Research Conference. DeLill Nasser Awards have two rounds of applications per year; one for courses and conferences occurring between January 1 and June 30, and another for courses and conferences occurring between July 1 and December 31. Monitor the GSA e-News and homepage (www.genetics-gsa.org) for updates regarding application windows.

The GSA encourages all of its members and friends to donate. Please make your check payable to The Genetics Society of America and send it to Adam Fagen, Executive Director, GSA, 9650 Rockville Pike, Bethesda, MD 20814-3998. Please write “Nasser Fund” on the bottom left of the check.

Poster Award Competition

Posters are an important component of the Drosophila meeting and the Poster Award appropriately highlights the work that goes into a professional presentation of outstanding science.

Nine awards will be given for the best poster designs. First ($500), second ($300) and third ($200) place prizes will be given to the undergraduate students, graduate students and postdocs judged to have the best posters. Both scientific merit and clarity of presentation will be evaluated. To be eligible, your poster must be displayed from 11:00 pm on March 26 through 10:00 pm on March 29, 2014. Additionally, your poster number, which will be preset, should not be moved or covered. Posters that are removed, not displayed or don’t adhere to poster display guidelines will not be considered.

This competition is only open to students and postdocs who are members of GSA. PI's are not eligible.

If you are a session chair you should submit your selections for top undergraduate, graduate and postdoc in your section via e-mail to Ela Serpe at [email protected] by 7:00 p.m. on Friday, March 28. Please put “poster awards” in the subject line.

Award Winners – Please bring and display your posters in the Atlas Ballroom Foyer on Sunday, March 30 by 7:00 a.m. (boards will be available beginning at 5:00 p.m. on Saturday, March 29). Your award will be presented during the Sunday morning Plenary Session.

SPONSORS AND EXHIBITORS

We would like to thank the following companies for their support of the 55th Annual Drosophila Research Conference . Please visit the exhibits in the Grand Exhibit Hall and take advantage of the opportunity to see the new products, publications and services available from these companies.

GRAND SPONSOR

EVENT SPONSORS

The journals GENETICS and G3: Genes|Genomes|Genetics Sponsors of the Opening Reception on Wednesday, March 26

SPONSORS AND EXHIBITORS

Archon Scientific Booth #209 Carl Zeiss Microscopy, LLC Booth #117 2236B Ferrell Rd. One Zeiss Drive Durham, NC 27704 Thornwood, NY 10594 Phone: 919/627-7751 Phone: 800/233-2343 Fax: 908/923-8241 E-mail: [email protected] E-mail: [email protected] URL: www.zeiss.com/microscopy URL: www.ArchonScientific.com As the world's only manufacturer of light, X-ray and Quality fly food - ready-made on demand. electron microscopes, ZEISS offers tailor-made microscope systems for 3D imaging in biomedical Azer Scientific, Inc. Booth #306 research, life sciences and healthcare. A well-trained 189 Twin Couny Road sales force, an extensive support infrastructure and a Morgantown, PA 19543 responsive service team enable customers to use their Phone: 610/524-5810 ZEISS microscopes to their full potential. Fax: 610/901-3046 E-mail: [email protected] Darwin Chambers Company Booth #212 URL: AzerSci.com 2945 Washington Ave. St. Louis, MO 63103 Azer Scientific is the one source for all of your Phone: 877/783-6774 drosophila lab needs, from bottles and vials, to our Fax: 877/783-6774 fly food and anesthetizing equipment! Our friendly E-mail: [email protected] and knowledgeable team is always available to help URL: www.darwinchambers.com with your drosophila needs. Stop by our booth to learn more! Darwin Chambers specializes in providing custom insect rearing chambers and rooms. Our liquid- BioCold Environmental, Inc. Booth #107 circuited cooling with electric reheat increases energy 239 Seebold Spur efficiency, and minimizes corrosion concerns. Built- Fenton, MO 63026 in redundancy in our thermoelectric systems provides Phone: 636/349-0300 unsurpassed reliability. Other advantages are reduced Fax: 636/349-0419 noise and vibration, durability, and ease of E-mail: [email protected] maintenance. Options include diurnal lighting and URL: www.biocold.com/drc ultrasonic humidification.

For 15 years, BioCold Environmental has been a leader in Drosophila incubator innovation. Stop by our booth to learn how Peltier solid-state cooling makes compressor failures and refrigerant leaks a thing of the past. With a 3-year bumper to bumper warranty, BioCold incubators offer industry-leading performance and reliability starting under $7,000.

SPONSORS AND EXHIBITORS

Drosophila Genomics Resource Center (DGRC) Genetic Services Inc. Booth #109 Booth #215 One Kendall Square, Bldg. 300 1001 E 3rd Street, Indiana University Cambridge, MA 02139 Bloomington, IN 47408 Phone: 617/872-3135 Phone: 812/855-7577 Fax: 617/252-9119 Fax: 812/856-9340 E-mail: [email protected] E-mail: [email protected] URL: www.geneticservices.com URL: https://dgrc.cgb.indiana.edu Genetic Services Inc. offers a variety of services for The Drosophila Genomics Resource Center the Drosophila Community including P-element and (http://www.dgrc.cgb.indiana.edu) serves the site directed injections, fosmid, Bac and mimic Drosophila community by collecting and distributing injections, transgenic production, Talen and Crispr clones and cell lines of general interest and by mutant stock production, mosquito injections, fly assisting the community in using these materials. food production, stock maintenance, in vitro Visit our booth for information about upcoming mutagenesis, DNA and RNA preparation and more. services or to speak to DGRC personnel about our Let us speed up your research and make your lab materials. more competitive!

Genesee Scientific Booths #213/312 Genetics Society of America Booth #207 8430 Juniper Creek Lane 9650 Rockville Pike San Diego, CA 92126 Bethesda, MD 20814-3998 Phone: 800/789-5550 Phone: 301-634-7371 Fax: 888/789-0444 Fax: 301/634-7079 E-mail: [email protected] E-mail: [email protected] URL: www.geneseesci.com URL: www.genetics-gsa.org

Don’t miss new additions to Genesee’s Come explore the resources and opportunitities that comprehensive “Flystuff™” catalog (available GSA has to offer including education, career worldwide) featuring the new INVICTUS™ development, and policy; meet members of the GSA Drosophila-specific incubator; new advancements on staff and leadership; and find out about publishing in our patented vial reload system, the environmentally GENETICS and G3: Genes|Genomes|Genetics. responsible and cost effective alternative to pre- racked vials; and also our latest innovations in NightSea Booth #314 Drosophila Anesthesiology! We offer interactive 34 Dunelm Rd. demonstrations and expert consultation. Bedford, MA 01730 Phone: 781/791-9508 Fax: 781/791-9519 E-mail: [email protected] URL: www.nightsea.com

NIGHTSEA features its popular, economical system that adapts existing stereo microscopes for fluorescence. Widely used in the Drosophila community for screening and sorting transgenic flies, and for undergraduate education and K-12 outreach. Visit our booth to see four excitation/emission combinations and a new product for creating darkness around your microscope.

SPONSORS AND EXHIBITORS

Parter Medical Products, Inc. Booth #206 Rainbow Transgenic Flies Inc. Booth #214 17015 Kingsview Avenue 3251 Corte Malpaso, Suite 506 Carson, CA 90746 Camarillo, CA 93012 Phone: 800/666-8282 Phone: 805/482-2277 Fax: 310/327-8601 Fax: 805/482-1152 E-mail: [email protected] E-mail: [email protected] URL: www.partermedical.com URL: www.rainbowgene.com

Parter Medical is the leading manufacturer of high Located in beautiful California, RTF has been quality plasticware for Drosophila research. Our serving Drosophila fly community since 2004. Top disposable/reusable vials and bottles are made in a quality of transgenic fly services and customer wide selection of sizes, materials, and packaging satisfaction are our ultimate goal. We offer choices. All of our products are manufactured for competitive price, fast turn-around time and optimum durability and offer excellent value. Stop by guaranteed rate of transformation, which make RTF and see why our fresh ideas lead to great Drosophila an affordable and reliable resource for your research products. needs.

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Percival Scientific's cutting edge technology is at the Sable Systems International is the widely cited, core of our commitment to delivering the best international standard in high resolution metabolic products on the market today. This commitment is screening and calorimetry. Our systems can measure clear with the Percival DR-36 and DR-41 Series Drosophila gas exchange in real time. Technical which are dedicated to offer the best features for support is by published experts in insect Drosophila research. respirometry. Please drop by our booth and discuss what we can do for your research. Powers Scientific, Inc. Booth #115 P O Box 268 Union Biometrica, Inc. Booth #216 Pipersville, PA 18947 84 October Hill Rd. Phone: 215/230-7100 Holliston, MA 01706 Fax: 215/230-7200 Phone: 508/893-3115 E-mail: [email protected] Fax: 508/893-8044 URL: www.powersscientific.com E-mail: [email protected] URL: www.unionbio.com Powers Scientific, Inc. - offering Drosophila growth chambers with coated coils in 6 sizes (from 6-55 c.f. Union Biometrica Large Particle Flow Cytometers capacity) with four levels of temperature, humidity automate the analysis, sorting & dispensing of and lighting control to fit the application and price objects too big/fragile for traditional cytometers, e.g., range. Mosquito, Sand Fly and c. Elegans growth small model organisms like Drosophila, large cells / chambers also available. cell clusters, and beads. COPAS or BioSorter with interchangeable modules cover the full 10-1500μm range and are ideal for shared instrument grants.

SPONSORS AND EXHIBITORS

Vienna Drosophila RNAi Center Booth #308 The VDRC is a non-profit research organization Dr. Bohr - Gasse 3 maintaining and distributing over 40,000 transgenic Vienna, Austria 1030 fly stocks to the world-wide Drosophila community. Phone: +43 1 7962324 7027 Current stocks include a genome-wide RNAi Fax: 43 17904422 4546 collection and Vienna Tiles Gal4 lines. We welcome E-mail: [email protected] donations of new resources and are open to URL: www.vdrc.at collaborations for further development.

POSTERS AND EXHIBITS FLOORPLAN

OPENING AND PLENARY SESSIONS

Wednesday, March 26 7:00 PM–9:15 PM Thursday, March 27 8:30 AM–12:00 NOON

Opening General Session Plenary Session I

Co-Moderators: Mark Van Doren, Johns Hopkins Moderator: Daniela Drummond-Barbosa, Johns University, Baltimore, Maryland and Elissa Lei, Hopkins University, Baltimore, Maryland NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland Room: Atlas Ballroom

Room: Atlas Ballroom Presentations:

Presentations: 8:30 am Image Award Presentation. David Bilder. University of California, Berkeley. 7:00 pm Welcome and Opening Remarks. Mark Van Doren. Johns Hopkins University, Baltimore, 8:35 am Controlling Morphogen Gradients. Arthur Maryland. D. Lander. Dept Dev Cell Biol and Dept of Biomedical Engineering, Univ California, Irvine, 7:10 pm GSA Welcome and Update. Adam Fagen. Irvine, CA. Genetics Society of America, Bethesda, Maryland. 9:05 am Fat Cadherins in Growth, Planar Polarity 7:20 pm Larry Sandler Award Presentation. Ken and Mitochondrial Activity. Helen McNeill. Irvine. Rutgers University, Waksman Institute, Lunenfeld-Tanenbaum Institute, Mt Sinai Hospital , Piscataway, New Jersey. Toronto, ON, Canada; Dept. Molecular Genetics, University of Toronto Toronto, Canada. 7:25 pm Larry Sandler Lecture. 9:35 am Epigenetic Regulation of Drosophila Male 7:55 pm Keynote Introduction. Elissa Lei. Germ Cell Differentiation. Xin Chen. Dept Biol, NIH/National Institute of Diabetes and Digestive and Johns Hopkins Univ, Baltimore, MD. Kidney Diseases, Bethesda, Maryland. 10:05 am - Break 8:00 pm Science, Biology, and the World’s Future. Bruce Alberts. UCSF, San Francisco, CA. 10:30 am X Marks the Spot: Targeting the X Chromosome During Dosage Compensation. Erica 9:00 pm Presentation of George W. Beadle Award N. Larschan. Molec Biol, Cellular Biol & Biochem, to Hugo Bellen, Baylor College of Medicine/HHM). Brown Univ, Providence, RI.

11:00 am Circuit Mechanisms Underlying Behavioral Decisions and Motor Program Sequencing in Ecdysis. Benjamin H. White. Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD.

11:30 am The Molecular Evolution of Morphology and Behavior. David L. Stern. Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA.

OPENING AND PLENARY SESSIONS

Notes Sunday, March 30 8:30 AM–12:00 NOON

Plenary Session II

Moderator: Mihaela Serpe, NIH/National Institute of Child Health and Human Development, Bethesda, Maryland

Room: Atlas Ballroom

Presentations:

8:30 am Poster Award Presentation. Mihaela Serpe. NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.

8:35 am Charting the Genotype-Phenotype Map: Lessons from Drosophila. Trudy F. Mackay. Dept Biological Sciences, North Carolina State Univ, Raleigh, NC.

9:05 am Walking the Highwire from Synaptic Growth to the Axon Injury Response Pathway. Aaron DiAntonio. Dept of Developmental Biology, Washington University School of Medicine, St. Louis, MO.

9:35 am piRNAs Function for the Safeguard of Germline Genome. Toshie Kai. Temasek Lifesciences Laboratory/Dept. Biological Science, National University of Singapore, Singapore.

10:05 am - Break

10:30 am Multiple Layers of Complexity in the Regulation of the Bithorax Complex. Francois Karch. Dept Genetic and Evolution, Univ Geneva, Geneva, Switzerland.

11:00 am Cardiomyopathy Models. Rolf Bodmer. Development and Agi, Sanford-Burnham Medical Research Institute, La Jolla, CA.

11:30 am The Conflicted Existence of the Mitochondrial Genome. Patrick H. O'Farrell. Dept Biochemistry, Univ California, San Francisco, CA.

WORKSHOPS

Wednesday, March 26 12:00 NOON–6:00 PM Friday, March 28 1:45 PM–3:45 PM

Ecdysone Workshop Flies on Drugs - Screening for Therapeutics in Drosophila

Room: Pacific Ballroom Salon 3 Room: Pacific Ballroom Salons 4-5 Organizers: Ginger Carney, Texas A&M Organizers: Daniela Zarnescu, University of University, and Arizona, Tucson, and Laurie von Kalm, University of Central Tin Tin Su, University of Colorado, Florida Boulder

The Ecdysone Workshop welcomes all those Recent successes using Drosophila for drug screening interested in insect endocrinology. Importantly, this have brought attention to the fly as an emerging workshop is a forum to discuss the role of different model that holds great promise for the rapid hormones (e.g., 20-hydroxyecdysone, juvenile discovery of high quality therapeutic leads. Talks hormone, peptide hormones, insulin) and the from expert speakers will focus on the challenges and crosstalk between their signaling pathways. The opportunities of screening for therapeutics in the fly. topics covered include, but are not limited to, Topics will include screening approaches using hormone synthesis and secretion, and hormonal various paradigms ranging from behavior to cancer to control of transcription, differentiation, neurodegeneration models. A summary discussion morphogenesis, growth, metabolism, timing and will focus on identifying opportunities and challenges behavior. Platform talks of 15 minutes will be associated with using Drosophila for drug discovery, selected from interested applicants and grouped into and strategies for increasing its visibility with sessions, with each session highlighted by an invited funding agencies and pharmaceutical companies. speaker. To apply and/or receive the final program, please email the organizers ([email protected] or [email protected]). Friday, March 28 1:45 PM–3:45 PM

Developmental Mechanics Friday, March 28 1:30 PM–4:00 PM Room: Pacific Ballroom Salon 3 Undergraduate Plenary Session and Workshop Organizers: Guy Tanentzapf, University of British Columbia, Vancouver Canada, and Room: Royal Palm Ballroom 5-6 Rodrigo Fernandez-Gonzalez, University Organizers: Alexis Nagengast, Widener University, of Toronto, Canada and Beth Ruedi, Genetics Society of D'Arcy Thompson, in his seminal book on growth America, Bethesda, Maryland and form, proposed that physical forces play a central role in animal development. Over the last twenty Undergraduate conference attendees will attend an years, the establishment of tools to measure and "Undergraduate Plenary Session" from 1:30-2:45 pm, manipulate mechanical forces in living organisms has with two talks presented at a level appropriate for an demonstrated that indeed mechanical forces influence undergraduate audience. From 3:00-4:00 pm, molecular dynamics and cell behaviors during tissue undergraduates will have a chance to talk to a panel morphogenesis. In this workshop, we will review the of graduate students about applications, interviewing, most recent technical advances to visualize and admission, choosing a lab, and quality of life in quantify force generation during Drosophila graduate school. development, and we will discuss the latest results demonstrating the interplay between physical forces, molecular dynamics and tissue morphogenesis.

WORKSHOPS

Friday, March 28 1:45 PM–3:45 PM Friday, March 28 1:45 PM–3:45 PM

Drosophila Male Fertility as a Cell Biological Extracellular Epithelial Barriers Model Room: Pacific Salon 6 Room: Pacific Ballroom Salon 7 Organizers: Edward Blumenthal, Marquette Organizers: Julie Brill, The Hospital for Sick University, Milwaukee, Wisconsin, and Children, Toronto, Canada, and Bernard Moussian, University of Mariana Wolfner, Cornell University, Tuebingen, Germany Ithaca, New York Tissues exposed to potentially hostile environments This workshop will showcase the exciting progress in produce protective extracellular barriers such as the Drosophila male fertility research, and at the same external and tracheal cuticle, the eggshell, and the time highlight how the special features of the midgut peritrophic matrix. In the past few years, Drosophila male reproductive system provide a using the fruit fly as a model organism, a growing powerful way to dissect cell biological processes of body of research has examined the molecular and general importance. After a brief historical overview, genetic mechanisms of barrier formation. This the workshop will feature talks that focus on novel workshop will feature presentations and discussion cellular mechanisms that underlie Drosophila covering the biochemistry, cell biology, and genetics spermatogenesis and male fertility. Topics will of barrier synthesis and stabilization and techniques include recent advances in understanding the available for studying the properties of these biogenesis and function of sperm and accessory gland structures. organelles, mitochondrial morphogenesis, microtubule organization, individualization, exosome biology, and paternal contributions to embryogenesis. Saturday, March 29 6:45 PM–8:45 PM

Drosophila Metabolomics Workshop Friday, March 28 1:45 PM–3:45 PM Room: Golden Pacific Ballroom The Practice and Promise of CRISPR/Cas9- Organizers: Thomas Merritt, Laurentian mediated Genome Engineering University, Sudbury, Canada, and Daniel Promislow, University of Room: Pacific Ballroom Salon 1 Washington, Seattle, and Organizers: Melissa Harrison, University of Jason Tennessen, Indiana University, Wisconsin, Madison, and Bloomington Kate O'Connor-Giles, University of Wisconsin, Madison Metabolomics is emerging as a powerful arm of the 'omics' world, linking genetic and environmental The bacterial CRISPR/Cas9 system was recently factors with downstream phenotypes and adapted for genome editing in many organisms, metabolomic studies are becoming increasingly including Drosophila. The workshop will highlight common in Drosophila research. The "Drosophila the rapid advances in how this exciting new system is metabolomics workshop" seeks to promote a shared being used for genome engineering and encourage approach to developing new methods in Drosophila- discussion of methods for expanding the utility of focused metabolomics research. This workshop is an this technology. Speakers will present their work on outgrowth of the recently created International topics including optimizing the system in Drosophila, Drosophila Metabolomics Curation Consortium, balancing efficiency and specificity, and expanding which aims to facilitate metabolomics research by its application for generating a range of genome promoting standardization and sharing of protocols, modifications. Following the talks, a question-and- results and best practices. Workshop discussion answer discussion forum will promote a dynamic topics will include: potential reference fly strains, exchange of ideas on creative strategies for future standardized controls and conditions, data analysis applications. and data storage, and current metabolomic studies.

WORKSHOPS

Saturday, March 29 6:45 PM–8:45 PM Saturday, March 29 6:45 PM–8:45 PM

Wound Healing and Regeneration Drosophila Research and Pedagogy at Primarily Undergraduate Institutions (PUI) Room: Pacific Ballroom Salon 3 Organizers: Adrian Halme, University of Virginia Room: Pacific Ballroom Salons 4-5 School of Medicine, Charlottesville, and Organizers: Scott Ferguson, SUNY, Fredonia, New Rachel Smith-Bolton, University of York, and Illinois, Urbana-Champaign Jennifer Kennell, Vassar College, Poughkeepsie, New York Drosophila has become an important model system for understanding both wound healing and This workshop focuses on increasing the quality and regeneration of tissues and organs. The goal for this visibility of Drosophila research performed at workshop is to bring together presentations of recent primarily undergraduate institutions (PUIs) and work from researchers studying tissue repair in facilitating faculty and students in these endeavors. diverse contexts. This workshop will highlight and The goals include: 1) Encouraging undergraduate encourage discussion of the themes in this field research by providing a forum for students to make including, but not limited to: the roles of stem cells, oral presentations; 2) Connecting people interested in cell biological and mechanical mechanisms, and this career path with current PUI faculty; 3) inflammatory and innate immune systems in tissue Establishing a network among current PUI faculty to repair and regeneration in different developmental promote discussion and provide support on and adult tissues. professional issues that differ from those at large institutions; 4) Sharing concepts and techniques that encourage the integration of Drosophila as a teaching Saturday, March 29 6:45 PM–8:45 PM tool in the classroom and laboratory.

Data-driven Mathematical Modeling in Drosophila as a Tool for Discovery Saturday, March 29 6:45 PM–8:45 PM

Room: Pacific Ballroom Salon 7 Genetic, Genomic and Informatic Resources for Non-melanogaster Drosophilidae Organizer: David M Umulis, Purdue University, West Lafayette, Indiana Room: Pacific Ballroom Salon 1 The integration of mathematical modeling with Organizers: William Gelbart, Harvard University, diverse imaging strategies in Drosophila has led to a Cambridge, Massachusetts, and number of new discoveries in the areas of network Therese Markow, University of inference, the mechanics of morphogenesis, spatial California, San Diego pattern formation, cell-fate determination, among many others. In this workshop we investigate how Many species of the family Drosophilidae are researchers are bridging the gaps between actively used for studies of evolution, population experimental data and mathematical models to variation and ecology and comparative functional inform our understanding of mechanism and drive analyses (as well as for many other purposes). Given discovery in Drosophila. Specific topics include limitations on available resources for reference Model-Based Optimal Design of Experiments (MB- strains and mutations at the Drosophila Species Stock ODE), the integration of data into model design and Center and for informatics support at FlyBase, it is optimization, and the mathematical modeling of essential to develop a community-supported morphogenesis. consensus on priorities for these resources and to think about other resources that may be needed. This workshop is intended to provide a forum for discussion of possible options and priorities at this critical juncture in our rapidly expanding assemblage of information.

WORKSHOPS

Saturday, March 29 9:15 PM–11:15 PM Saturday, March 29 9:15 PM–11:15 PM

Everything You Ever Wanted to Know About Sex Centrosomes and Cilia in Cell Division and Disease Room: Pacific Ballroom Salon 3 Organizers: Artyom Kopp, University of California, Room: Pacific Ballroom Salon 7 Davis, and Organizers: Tim Megraw, Florida State University, Michelle Arbeitman, Florida State Tallahassee, and University, Tallahassee Tomer Avidor-Reiss, University of Toledo, Ohio The workshop will cover the molecular genetics, development, neurobiology, genomics, evolution, and This workshop will unite the centrosome and cilium population genetics of sexual dimorphism, with an research community at a rare forum focused on the emphasis on cross-disciplinary interactions. centrosome/cilium complex and its role in cell Presentations by invited speakers and selected division, stem cell biology, development and disease. abstracts from each discipline will be followed by moderated discussions. The speakers are encouraged to summarize the key ideas behind their research for people working in other fields, outline the main unsolved questions, offer their opinions about future directions, and suggest connections that could be built with other disciplines.

Saturday, March 29 9:15 PM–11:15 PM

Feeding Behavior, Nutrition and Metabolism

Room: Golden Pacific Ballroom Organizers: Tânia Reis, University of Colorado School of Medicine, Aurora, and William W Ja, The Scripps Research Institute, Jupiter, Florida

Drosophila has become as a powerful model system for studying how diet and nutrition can influence a wide range of metabolic processes. This workshop is designed to assemble a diverse group of presentations that highlight recent advances in the field of nutrition and metabolism. The goal of this workshop is to foster discussions and encourage collaborations among individuals interested in topics ranging from food intake as a fundamental parameter of metabolism to the effects of diet on energy storage and utilization.

SCHEDULE OF EVENTS, EXHIBITOR LIST, REGISTRANT LIST, AND MORE

AVAILABLE ON YOUR SMARTPHONE

m.dros-conf.org

To use the above QR code, go to your app store or you can go to www.mobile-barcodes.com to find the QR code reader for your mobile phone. Click on the reader to get further instructions and a quick link to download the application. Install the application on your device.

To the Organizers and Session Chairs who spent countless hours reviewing abstracts and developing the program. Organizers

Daniela Drummond-Barbosa Elissa Lei Mihaela Serpe Mark Van Doren

Session Chairs

Christian Bökel Susan Harbison Vincenzo Pirrotta Gabrielle Boulianne Volker Hartenstein James Posakony Mike Buszczak Robin Hiesinger Noreen Reist Laura Buttitta Tom Kornberg Amanda Simcox Maya Capelson Martin Kreitman Michelle Starz-Gaiano Sue Celniker Charles Langley Carl Thummel Sara Cherry Paul Lasko Tina Tootle Rachel Cox Chi-Hon Lee Esther Verheyen Cassandra Extavour Pierre Leopold Kevin White Nathalie Franc Michael Levine Tian Xu Amin Ghabrial John Manak Bing Zhang Kent Golic Terry Orr-Weaver Rui Zhou Alex Gould Lori Pile

CONCURRENT PLATFORM SESSIONS THURSDAY, MARCH 27 4:30-6:30 PM Presenting author is in bold. Full abstracts can be found online.

Cell Division and Growth Control Neural Development

Co-Moderators: Laura Buttitta, University of Michigan, and Alex Co-Moderators: Robin Hiesinger, UT Southwestern, Dallas, Texas Gould, MRC National Institute for Medical Research, London, UK and James Posakony, University of California, San Diego

Room: Town & Country Room: Golden West

1 - 4:30 9 - 4:30 Re-replication during Follicle Cell Gene Amplification causes Chromatin modulation in structural and functional refinement of replication fork instability and requires double-strand break repair. fru+ ORN circuits in Drosophila. Pelin C. Volkan1,2,3, Doug Jessica L. Alexander, Terry L. Orr-Weaver. Whitehead Inst for Olsen1, Catherine Hueston2, Qingyun Li1, Jianni Wu4. 1) Duke Biomedical Research/Dept. of Biology, MIT, Cambridge, MA. University, Department of Biology, Durham, NC; 2) Duke University, Department of Neurobiology, Durham, NC; 3) Duke 2 - 4:45 Institute of Brain Sciences; 4) Duke Univeristy, Undergraduate Regulation of cilium and centrosome function by rootletin. Jieyan Program in Neuroscience, Durham, NC. Chen, Timothy Megraw. Biomedical Sciences, Florida State University, Tallahassee, FL. 10 - 4:45 Intravital 2-photon imaging and computational modeling reveal 3 - 5:00 simple pattern formation rules underlying neural superposition. The Drosophila orthologue of human GOLPH3 is required for Egemen Agi1,5, Marion Langen2,5, Dylan Altschuler2,3, Lani Wu2,4, contractile ring formation and membrane trafficking during Steven Altschuler2,4, Peter Robin Hiesinger1,2,4. 1) Department of cytokinesis. Maria Grazia Giansanti1, Giorgio Belloni2, Gianni Physiology, Univ of Texas Southwestern Med Center, Dallas; 2) Colotti1, Vincenzo Mattei3, Anna Frappaolo1, Grazia Daniela Green Center for Systems Biology, Dept of Pharmacology, Raffa2, Margaret T. Fuller4, Stefano Sechi1. 1) IBPM, Consiglio Simmons Cancer Center, Univ of Texas Southwestern Medical Nazionale delle Ricerche, Rome, Italy; 2) Dipartimento di Biologia Center, Dallas; 3) STARS program, Univ of Texas Southwestern e Biotecnologie, Università Sapienza, Rome, Italy; 3) Laboratory Med Center, Dallas; 4) Co-corresponding; 5) Equal contribution. of Experimental and Environmental Pathology, Sabina Universitas, Rieti, Italy; 4) Departments of Developmental Biology and 11 - 5:00 Genetics, Stanford University School of Medicine, Stanford, USA. Role of microRNA machinery in dendrite patterning. Marvin Nayan1, Charlie Kim2, Jay Parrish1. 1) Dept. of Biology, 4 - 5:15 University of Washington, Seattle, WA; 2) Division of Adenosine is a paracrine homeostatic signal affecting growth of Experimental Medicine, University of California San Francisco, wts tumor clones. Michal Zurovec, Roman Sidorov, Lucie Kucerova. Biology Centre CAS, Ceske Budejovice, Czech 12 - 5:15 Republic. Drosophila Mitofusin affects mitochondrial trafficking, steroid- hormone production and NMJ maturation. Hector Sandoval1, Chi- 5 - 5:30 Kuang Yao1,4, Kuchuan Chen2, Taraka Donti1, Manish Jaiswal3, Growth control by the conserved Aac11/Api5 anti-apoptotic Yong-Qi Lin3,5, Shinya Yamamoto1,2, Brett Graham1, Hugo protein. Can Zhang1, Wenjian Xu2, Alexey Veraksa2, Kenneth Bellen1,2,3. 1) Human and Molecular Genetics; 2) Program in Moberg1. 1) Department of Cell Biology, Emory University, Development Biology; 3) Howard Hughes Medical Institute, Atlanta, GA; 2) Department of Biology, University of BCM, Houston, TX; 4) Academia Sinica, Institute Institute of Massachusetts Boston, Boston, MA. Biological Chemistry, Taipei, Taiwan; 5) Garvan Institute of Medical Research, Neuroscience Program, Sidney, Australia. 6 - 5:45 The Drosophila TNF receptor Grindelwald couples loss of cell 13 - 5:30 polarity with neoplastic growth. Julien Colombani1, Ditte Crimpy enables discrimination of pre and postsynaptic pools of a Andersen1, Krittalak Chakrabandhu1, Michael Röthlisberger2, BMP at the NMJ. Rebecca James1, Kendall Hoover1, Chris Anne-Odile Hueber1, Konrad Basler2, Pierre Leopold1. 1) Wilson1, Kristi Wharton2, Ed Levitan3, Heather Broihier1. 1) University of Nice Sophia Antipolis, CNRS UMR7277, INSERM Neurosciences, Case Western Reserve University, Cleveland, OH; U1091, Intitute of Biology Valrose, Nice, France; 2) Inst of 2) Molecular Biology, Cell Biology, and Biochemistry, Molecular Life Sciences, Univ of Zurich, Zurich, Switzerland. Providence, Brown University, RI; 3) Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA. 7 - 6:00 An evolutionarily conserved role for plexins during epithelial 14 - 5:45 wound repair in Drosophila and zebrafish. Sa Kan Yoo1,2, Iswar Local BMP signaling sculpts synapse development at the Hariharan1. 1) UC-Berkeley, Berkeley, CA; 2) Miller institute, Drosophila neuromuscular junction. Mikolaj J. Sulkowski, UC-Berkeley, Berkeley, CA. Mihaela Serpe. NICHD, National Insts of Health, Bethesda, MD.

8 - 6:15 15 - 6:00 Src64 generates a gradient of tyrosine phosphorylation and Xbp1-Independent Ire1 Signaling Is Required for Photoreceptor controls actin dynamics during incomplete cytokinesis in the Differentiation and Rhabdomere Morphogenesis in Drosophila. Drosophila male germline. Asmund H. Eikenes1,2, Catherine Sem Dina S. Coelho1, Fátima Cairrão1, Xiaomei Zeng2, Elisabete Wegner1,2, Lene Malerød1,2, Andreas Brech1,2, Knut Liestøl2, Pires1, Ana V. Coelho1, David Ron3, Hyung Don Ryoo2, Pedro M. Harald Stenmark1,2, Kaisa Haglund1,2. 1) Department of Domingos1. 1) Instituto de Tecnologia Química e Biológica, 2780- Biochemistry, Institute for Cancer Research, Oslo University 157 Oeiras, Oeiras, Portugal; 2) Department of Cell Biology, New Hospital, Montebello, Oslo, Norway; 2) Centre for Cancer York University School of Medicine; 3) Metabolic Research Biomedicine, Faculty of Medicine, University of Oslo, Laboratory and NIHR Cambridge Biomedical Research Centre, Montebello, Oslo, Norway. University of Cambridge, Addenbrooke’s Hospital.

CONCURRENT PLATFORM SESSIONS THURSDAY, MARCH 27 4:30-6:30 PM Presenting author is in bold. Full abstracts can be found online.

16 - 6:15 An E3 ubiquitin ligase regulates neural-specific glycosylation in Notes the Drosophila embryo. Nickita Mehta, Mary Sharrow, Katherine Tiemeyer, Toshiko Katoh, Michael Tiemeyer. Biochemistry and Mol. Biology, Complex Carbohydrate Research Center, UGA, Athens, GA.

Organogenesis and Gametogenesis

Co-Moderators: Rachel Cox, Uniformed Services University of the Health Sciences, Bethesda, Maryland and Amin Ghabrial, University of Pennsylvania, Philadelphia

Room: California 17 - 4:30 Alien, a highly conserved COP9 Signalosome (CSN) subunit, maintains the cellular microenvironment for germline cells in testes of Drosophila melanogaster. Yue Qian, Chun Ng, Cordula Schulz. Cellular Biology, University of Georgia, Athens, GA.

18 - 4:45 Loss of the nuclear envelope protein Otefin causes germline stem cell death due to activation of Checkpoint kinase 2. Lacy J. Barton, Kaylee E. Lovander, Melinda J. Martin, Pamela K. Geyer. Dept Biochemistry, Univ Iowa, Iowa City, IA.

19 - 5:00 Steroid Signaling and SREBP coordinate germline lipid accumulation with dietary nutrients in Drosophila. Matt Sieber1,2, Allan Spradling1,2. 1) Emrbyology, Carnegie Institution for Science, Baltimore, MD; 2) HHMI.

20 - 5:15 A secretion-based mechanism for basement membrane remodeling during egg chamber elongation. Adam J. Isabella1,2, Sally Horne- Badovinac1,2. 1) Committee on Development, Regeneration, and Stem Cell Biology; 2) Department of Molecular Genetics & Cell Biology, University of Chicago, Chicago, IL.

21 - 5:30 Sunday Driver (Syd/JIP3) and JNK Signaling are Required for Myogenesis and Muscle Function. Victoria K. Schulman1,2, Eric S. Folker2, Mary K. Baylies1,2. 1) Weill Cornell Graduate School of Medical Sciences, New York, NY; 2) Sloan-Kettering Institute, New York, NY.

22 - 5:45 Org-1-Tup expressing alary muscles and "new" related muscles in the thorax connect different internal organs in the developing embryo. Laetitia Bataillé1, Hadi Boukhatmi1, Christoph Schaub2, Ingolf Reim2, Jean-Louis Frendo1, Manfred Frasch2, Alain Vincent1. 1) Developmental Biology Center, CNRS/Université de Toulouse, Toulouse, France; 2) Dept of Biology, University of Erlangen-Nuremberg, Erlangen Germany.

23 - 6:00 Mipp1 (Multiple Inositol Polyphosphate Phosphatase) dephosphorylates Inositol polyphosphates extracellularly to facilitate filopodia formation. Yim Ling Cheng, Deborah Andrew. Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD.

24 - 6:15 Caudal visceral mesoderm (CVM) cell migration is regulated by sphingolipids. Angelike M. Stathopoulos, Young-Kyung Bae. Div Biol, MC 114-96, Caltech, Pasadena, CA.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 8:30-10:15 AM Presenting author is in bold. Full abstracts can be found online.

Cell Cycle and Cell Death Evolution and Quantitative Genetics I

Co-Moderators: Nathalie Franc, The Scripps Institute, La Jolla, Co-Moderators: Susan Harbison, National Heart, Lung, and Blood California and Terry Orr-Weaver, Whitehead Institute, NIH, Bethesda, Maryland and Martin Kreitman, Institute/Massachusetts Institute of Technology, Cambridge University of Chicago, Illinois

Room: Town & Country Room: Golden West

25 - 8:30 32 - 8:30 Protein phosphatase 2A promotes cell cycle exit. Dan Sun, Laura Frequent sex chromosome transitions in Dipterans. Beatriz Buttitta. Molecular, Cellular and Developmental Biology, Vicoso, Doris Bachtrog. UC Berkeley, Berkeley, CA. University of Michigan, Ann Arbor, MI.

33 - 8:45 26 - 8:45 Female-expressed de novo genes in Drosophila. Li Zhao, David J. Coordination of Zygotic Genome Activation and the DNA Damage Begun. Dept of Evolution and Ecology, Univ of California Davis, Response at the MBT. Shelby A. Blythe, Eric F. Wieschaus.

Molecular Biology, Princeton University, Princeton, NJ. 34 - 9:00

Evolution of H3K27me3-marked chromatin in Drosophila is linked 27 - 9:00 to patterns of gene duplication and diversification. Robert Widespeard post-transcriptional changes control cell cycle Arthur1,2, Lijia Ma2,3, Matthew Slattery2,3,4, Rebecca Spokony2,3, alteration at the oocyte-to-embryo transition in Drosophila. Iva Alexander Ostapenko2,3, Nicholas Negre2,3,5, Kevin White1,2,3. 1) Kronja1, Bingbing Yuan1, Stephen Eichhorn1,2, Kristina Dzeyk3, Ecology and Evolution, University of Chicago 2) Institute for Jeroen Krijgsveld3, David Bartel1,2, Terry Orr-Weaver1,2. 1) Genomics and Systems Biology, University of Chicago and Whitehead Institute for Biomedical Research, Cambridge, MA; 2) Argonne National Laboratory, Chicago, Illinois, 3) Department of Department of Biology, MIT, Cambridge, MA; 3) European Human Genetics, University of Chicago 4) Department of Molecular Biology Laboratory, Heidelberg, Germany. Biomedical Sciences, University of Minnesota Medical School,

Duluth, 5). Université de Montpellier 2 and INRA, UMR1333 28 - 9:15 DGIMI, F-34095 Montpellier, France. Dying cells protect survivors from radiation-induced cell death.

TinTin Su, Amber Bilak, Lyle Uyetake. MCD Biology, University 35 - 9:15 of Colorado, Boulder, CO. Unusual Haplotype Structure and Reduced Recombination in

Chromosomal Rearrangements in Populations of Drosophila 29 - 9:30 pseudoobscura. Zach Fuller1, Gwilym Haynes1, Shannon A steroid-controlled global switch in sensitivity to apoptosis during Duggan2, Dianhuiz Zhu2, Stephen Richards2, Stephen Schaeffer1. Drosophila development. Yunsik Kang1, Arash Bashirullah2. 1) 1) The Pennsylvania State University, University Park, PA; 2) Lab Genetics, Univ Wisconsin-Madison, Madison, WI; 2) Sch Baylor College of Medicine, Houston, TX. Pharmacy, Univ Wisconsi-Madison, Madison, WI.

36 - 9:30 30 - 9:45 A novel cysteine-clamp gene establishes head-to-tail polarity in the The follicle cells non-autonomously contribute to the midge Chironomus riparius. Jeff Klomp1, Derek Athy1, Chun Wai developmental programmed cell death of the nurse cells during Kwan1, Natasha Bloch2, Thomas Sandmann3, Steffen Lemke4, Urs Drosophila oogenesis. Allison K. Timmons, Albert A. Schmidt-Ott1. 1) Dept. of Organismal Biology and Anatomy, Mondragon, Claire E. Schenkel, Jon Iker Etchegarary, Jeffrey University of Chicago; 2) Dept. of Ecology and Evolution, Taylor, Olivia Rudnicki, Kim McCall. Boston University, Boston, University of Chicago; 3) German Cancer Research Center MA. (DKFZ), Im Neuenheimer Feld 280, Heidelberg, Germany; 4)

Centre for Organismal Studies, Im Neuenheimer Feld 230, 31 - 10:00 Heidelberg, Germany. Starvation-induced Sbf/MTMR13 and Rab21 activity promotes

VAMP8 autophagosome-lysosome fusion. Steve Jean, Sarah Cox, 37 - 9:45 Amy Kiger. Division of Biological Sciences, University of Signatures of polygenic adaptation from common natural variants California San Diego, San Diego, CA. in egg size evolution in experimentally evolved Drosophila melanogaster. Aashish R. Jha1,2,3, Cecelia M. Miles4, Nodia Lippert4, Christopher D. Brown5, Kevin P. White1,2,3, Martin Kreitman1,3. 1) Institute for Genomics and Systems Biology, The University of Chicago; 2) Department of Ecology and Evolution, The University of Chicago, 3) Department of Human Genetics, The University of Chicago; 4) Department of Biology, Augustana College, Sioux Falls, SD; 5) Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

38 - 10:00 Genomics and the molecular basis of hybrid incompatibilities. Nitin Phadnis1, Emily Baker2, Jacob Kitzman3, Kimberly Frizzell1, Emily Hsieh4, Jay Shendure3, Harmit Malik4,5. 1) Department of Biology, University of Utah, Salt Lake City; 2) University of Wisconsin, Madison; 3) University of Washington, Seattle; 4) Fred Hutchinson Cancer Research Center, Seattle; 5) Howard Hughes Medical Institute.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 8:30-10:15 AM Presenting author is in bold. Full abstracts can be found online.

Pattern Formation Notes

Co-Moderators: Thomas Kornberg, University of California, San Francisco and Amanda Simcox, Ohio State University, Columbus

Room: California 39 - 8:30 Trunk cleavage is essential for Drosophila terminal patterning and occurs independently of Torso-like. Michelle A. Henstridge1, Travis K. Johnson1,2, James C. Whisstock2, Coral G. Warr1. 1) School of Biological Sciences, Monash University, Clayton VIC 3800 Australia; 2) Department of Biochemistry and Molecular Biology, Monash University, Clayton VIC 3800 Australia.

40 - 8:45 Myosin ID controls Planar Cell Polarity for proper Left/Right asymmetry. Nicanor Gonzalez-Morales, Jean-Baptiste Coutelis, Charles Géminard, Delphine Cérézo, Stephane Noselli. Institut de Biologie Valrose, iBV, University of Nice, CNRS, Inserm, NICE Cedex 2, France.

41 - 9:00 Dispersion via cytonemes: how the Hedgehog gradient forms in the Drosophila wing imaginal disc. Weitao Chen, Thomas Kornberg. Cardiovascular Research Institute, UCSF, San Francisco, CA.

42 - 9:15 A wing margin enhancer at nab is limited by dorsal-ventral, anterior-posterior, and distal-proximal signals in Drosophila wing imaginal discs. Albert Erives, Elizabeth Stroebele. Biology, University of Iowa, Iowa City, IA.

43 - 9:30 Using a Synthetic Gene Network to Model and Understand the Effects of Shuttling on Gene Expression Patterns. Ashley Ann Jermusyk, Gregory T. Reeves. North Carolina State University, Raleigh, NC.

44 - 9:45 Dynamic aspects of Bcd gradient formation contributing to scaling and robustness. Alexander V. Spirov1,2, David M. Holloway3. 1) Computer Science and CEWIT, Stony Brook University, NY, USA; 2) The Sechenov Institute of Evolutionary Physiology and Biochemistry, RAS, St-Petersburg, Russia; 3) Mathematics, British Columbia Institute of Technology, Burnaby, BC, Canada.

45 - 10:00 Hedgehog signaling regulates mechanical tension along the Drosophila anteroposterior compartment boundary. Katrin Rudolf1, Maryam Aliee2, Frank Jülicher2, Christian Dahmann1. 1) Technische Universität Dresden, Institute of Genetics, 01062 Dresden, Germany; 2) Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 10:45 AM-12:30 PM Presenting author is in bold. Full abstracts can be found online.

Cell Biology and Cytoskeleton Evolution and Quantitative Genetics II

Moderator: Michelle Starz-Gaiano, University of Maryland, Co-Moderators: Cassandra Extavour, Harvard University, Baltimore County Cambridge, Massachusetts and Charles Langley, University of California, Davis Room: Town & Country 46 - 10:45 Room: Golden West Mechanical force induced adherens junctions remodeling. Mo Weng1, Eric Wieschaus1,2. 1) Howard Hughes Medical Institute; 2) 53 - 10:45 Molecular Biology, Princeton University, Princeton, NJ. Genetic architecture of foraging behavior in natural Drosophila melanogaster population. Grace Y. C. Lee1, Wanhao Chi2, Qian 47 - 11:00 Yang1, Wei Du3, Susie A. Turkson2, Nicholas VanKuren1, Xiaoxi Cellular and molecular mechanisms of epithelial organization in Zhuang2, Manyuan Long1. 1) Department Ecology and Evolution, the Drosophila embryo. Masako Tamada, Jennifer Zallen. University of Chicago, Chicago, IL; 2) Department of Howard Hughes Medical Institute and Developmental Biology Neurobiology, University of Chicago, Chicago, IL; 3) Department Program, Sloan-Kettering Institute, NY. of Biology, Wayne State University.

48 - 11:15 54 - 11:00 Prickle/Spiny-legs isoforms control the polarity of the apical Quantitative genetics of caffeine resistance in Drosophila microtubule network in PCP. Katherine Sharp1,2, Jessica melanogaster. Chad A. Highfill, Michael A. Najarro, Stuart J. Olofsson1, Maja Matis1, Bomsoo Cho1, Jeffrey Axelrod1. 1) Macdonald. Department of Molecular Biosciences, University of Pathology, Stanford University School of Medicine, Stanford, CA; Kansas, Lawrence, KS. 66045. 2) Genetics, Stanford University School of Medicine, Stanford, CA. 55 - 11:15 Using engineered deletions in the study of behavioral evolution 49 - 11:30 between Drosophila species. Wesley G. Cochrane, Veronica A. Myonuclear shape and architecture is maintained by cooperative Cochrane, Thomas L. Turner. EEMB, UCSB, Santa Barbara, CA. activities between Spectraplakin-EB1 and Nesprin that link the microtubule network to the nuclear cytoskeleton. Shuoshuo 56 - 11:30 Wang, Talila Volk. Weizmann Institute of Science, Rehovot, Genome-wide association of Drosophila melanogaster nutritional Israel. responses to gut microbiota. John Chaston, Adam Dobson, Peter Newell, Chun-nin Wong, David Sannino, Sara Ali, Angela 50 - 11:45 Douglas. Cornell University - Entomology, Ithaca, NY. Myosin II-mediated mechanosensory response generates cortical resistance to podosome invasion in Drosophila myoblat fusion. Ji 57 - 11:45 Hoon Kim1, Yixin Ren2, Shuo Li1, Yee Kee2, Douglas Robinson2, Quantitative Characterization of Natural Variation in Elizabeth Chen1. 1) Molecular Biology and Genetics, Johns Heterochromatin of Drosophila melanogaster. Kevin H.-C. Wei, Hopkins University , Baltimore, MD; 2) Cell Biology, Johns Daniel A. Barbash, Andrew G. Clark. Molecular Biology and Hopkins University, Baltimore, MD. Genetics, Cornell, Ithaca, NY.

51 - 12:00 58 - 12:00 Clueless/dGRASP dependent unconventional protein secretion Selective and demographic determinants of latitudinal variation in differentiates the delivery of αPS2 integrin from that of βPS allele frequency in North American Drosophila melanogaster. integrin in the Drosophila muscle. Zongheng Wang1, Ze Liu1, Alan O. Bergland1, Ray Tobler3, Emily Behrman2, Katherine Nicole Green2, Catherine Rabouille3, Erika Geisbrecht1,2. 1) School O'Brien2, Josefa Gonzales4, Paul Schmidt2, Dmitri Petrov1. 1) of Biological Sciences, University of Missouri-Kansas City, Stanford, Stanford, CA; 2) University of Pennsylvania, Kansas City, MO; 2) Department of Biochemistry and Molecular Philadelphia, PA; 3) Institut de Biologia Evolutiva, Barcelona, Biophysics, Kansas State University, Manhattan, KS; 3) Hubrecht Spain; 4) Institute for Population Genetics, Vienna, Austria. Institute-KNAW & University Medical Center Utrecht, Utrecht, The Netherlands. 59 - 12:15 Convergent balancing selection on an antimicrobial peptide in 52 - 12:15 Drosophila. Robert L. Unckless, Virginia1 M. Howick, Brian P. Prostaglandins temporally regulate actin remodeling during Lazzaro. Entomology, Cornell University, Ithaca, NY. Drosophila oogenesis. Andrew Spracklen1, Daniel Kelpsch1, Xiang Chen1, Cassandra Spracklen2, Tina Tootle1. 1) Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA; 2) Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 10:45 AM-12:30 PM Presenting author is in bold. Full abstracts can be found online.

Chromatin and Epigenetics Notes

Moderator: Vincenzo Pirrotta, Rutgers University, Piscataway, New Jersey

Room: California

60 - 10:45 Identification of new regulators of three dimensional Polycomb organization by a microscopy-based genome-wide RNAi screen. Giacomo Cavalli, Inmaculada Gonzalez, Julio Mateos, Aubin Thomas. Institute of Human Genetics, CNRS, Montpellier, France.

61 - 11:00 Spatial and Temporal Dynamics of Heterochromatin DSB Repair: Novel Role of Nuclear Pores. Taeyun Ryu1, Hannah Hopp1, Ryan Kunitake1, Kate Bowlin1, Preethi V. Palagani1, Lars Israel2, Alex Imhof2, Gary H. Karpen3, Irene Chiolo1. 1) Molecular and Computational Biology Department, University of Southern California, Los Angeles, CA; 2) Ludwig Maximilian University of Munich, Germany; 3) Genome Dynamics Department, Lawrence Berkeley National Laboratory, Berkeley, CA.

62 - 11:15 Tet, the 5-methylcytosine oxidase, is essential in Drosophila. Fei Wang1,2, Svetlana Minakhina1,2, Tatyana Naryshkina1,2, Curtis Schauder1,2, Brinda Banerji1,2, Ruth Steward1,2. 1) Waksman Institute, Piscataway, NJ; 2) Rutgers University.

63 - 11:30 The role of Drosophila chromatin remodeling factor CHD1 in replication-independent chromatin assembly and in chromosome organization. Alexander Y. Konev, Anna A. Makase, Natalia V. Belyakova, Natalia L. Ronzhina, Maria A. Ignatyeva. Department of Radiation and Molecular Biophysics, St. Petersburg Nuclear Physics Institute, Gatchina, Leningrad District, Russian Federation.

64 - 11:45 Simple Sequence Repeats in Gene Regulation. Jaya Krishnan, Rakesh Mishra. Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India.

65 - 12:00 Transgenerational inheritance of nutrition-induced genome rearrangements. John C. Aldrich, Keith A. Maggert. Department of Biology, Texas A&M University, College Station, TX.

66 - 12:15 Maternal Haploid, the Drosophila ortholog of human Spartan, is required for the integrity of paternal chromosomes at fertilization. Laetitia Delabaere, Guillermo Orsi, Laure Sapey-Triomphe, Béatrice Horard, Pierre Couble, Benjamin Loppin. CGphiMC, CNRS UMR5534, Université Claude Bernard Lyon1, Villeurbanne, France.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 4:30-6:30 PM Presenting author is in bold. Full abstracts can be found online.

Physiology, Organismal Growth and Techniques and Resources Aging Co-Moderators: Kent Golic, University of Utah, Salt Lake City and Kevin White, University of Chicago, Illinois Co-Moderators: Pierre Leopold, Universite Nice Sophia Antipolis,

France and Carl Thummel, University of Utah, Salt Lake City Room: Golden West

Room: Town & Country 75 - 4:30

CIRPSR/Cas9-catalyzed homology-directed repair for complex 67 - 4:30 genome engineering in Drosophila. Kate M. O'Connor-Giles1,2, The Drosophila fat body controls nutrient flux via transcriptional Scott J. Gratz1, Fiona P. Ukken2, C. Dustin Rubinstein2. 1) mechanisms. Laura Palanker Musselman1, Jill Fink1, Zeke Laboratory of Genetics, University of Wisconsin, Madison, WI; 2) Maier2, Michael Brent2, Thomas Baranski1. 1) Endocrinology, Laboratory of Cell and Molecular Biology, University of Metabolism, and Lipid Research, Washington University School of Wisconsin, Madison, WI. Medicine, St. Louis, MO; 2) Department of Computer Science,

Washington University School of Medicine. 76 - 4:45

Expanding applications of CRISPR/Cas9 technology. Shu Kondo, 68 - 4:45 Ryu Ueda. National Institute of Genetics, Mishima, Japan. Suppression of insulin secretion by the decretin hormone

Limostatin. Ronald Wakim Alfa1,2, Sangbin Park1, Kathleen-Rose 77 - 5:00 Skelly1, Lutz Kockel1, Seung K. Kim1,3,4. 1) Developmental A highly efficient and specific gene mutagenesis technology for Biology, Stanford University School of Medicine, Stanford, CA; 2) Drosophila melanogaster. Jiang Xu1,2, Xingjie Ren1, Lu-Ping Neuroscience Program, Stanford University School of Medicine, Liu1,2, Jian-Quan Ni1. 1) Gene Regulatory Laboratory, School of Stanford, CA; 3) Howard Hughes Medical Institute, Stanford Medicine, Tsinghua University, Beijing 100084, China; 2) University School of Medicine, Stanford, CA; 4) Department of Tsinghua Fly Center, Tsinghua University, Beijing 100084, China. Medicine (Oncology), Stanford University School of Medicine,

Stanford, CA. 78 - 5:15

Golic+: Gene targeting during Oogenesis with Lethality Inhibitor 69 - 5:00 and CRISPR/Cas9. Hui-Min Chen1,2, Tzumin Lee1. 1) HHMI: Activin signaling mediates muscle-to-adipose communication in a Janelia Farm, Ashburn, VA; 2) Department of Neurobiology, mitochondria dysfunction-mediated obesity model. Wei Song, University of Massachusetts Medical School, Worcester, MA. Xiaochun Ni, Yanhui Hu, Edward Owusu-Ansah, Jonathan Zirin,

Norbert Perrimon. Genetics Dept, Harvard Medical School, 79 - 5:30 Boston, MA. The Genome Disruption Project: Protein tagging and gene

inactivation using MiMIC. Sonal Nagarkar Jaiswal1, Paolo 70 - 5:15 Mangahas1, Koen Venken1,6, Stephanie Anguiano-Zarate1, An organismal role of Dp53 in metabolic adaptation to nutrient Theodore Busby III1, Yuchun He3, Benjamin Booth5, Karen deprivation. Lara Barrio, Andrés Dekanty, Marco Milán. Institute Schulze3, Robert Levis4, Allan Spradling3,4, Roger Hoskin5, Hugo for Research in Biomedicine, Barcelona, Spain. Bellen1,2,3. 1) Molecular and Human Genetics, Baylor college of

medicine, Houston, TX; 2) Program in Developmental 71 - 5:30 Biology,BCM, Houston, TX; 3) Howard Hughes Medical Institute; Innate immune signaling in the Drosophila fat body blocks DILP 4) Department of Embryology, Carnegie Institution for Science, signaling by uncoupling PI(3,4,5)P production and Akt activation. 3 Baltimore, MD; 5) Life Sciences Division, LBNL, Berkeley, CA; Michelle L. Bland1, Moshe D. Bitterman2, Morris J. Birnbaum2. 1) 6) Verna and Marrs McLean Department of Biochemistry and Department of Pharmacology, University of Pennsylvania, Molecular Biology,BCM, Houston, TX. Charlottesville, VA; 2) Department of Medicine, University of

Pennsylvania, Philadelphia, PA. 80 - 5:45

An efficient and inexpensive method to generate customized 72 - 5:45 phiC31 landing sites. Jon-Michael Knapp, Phuong M. Chung, Feeding and fasting signals converge on LKB1 and SIK3 pathway Julie H. Simpson. HHMI/Janelia Farm Research Campus, to regulate lipid homeostasis in Drosophila. Sekyu Choi1, Ashburn, VA. Jongkyeong Chung1,2,3. 1) National Creative Research Initiatives

Center for Energy Homeostasis Regulation, Seoul, South Korea; 2) 81 - 6:00 Institute of Molecular Biology and Genetics, Seoul, South Korea; Quantitative phenotyping of Drosophila larvae crawling with 3) School of Biological Sciences, Seoul National University, predictive power. Maximilian N. Guenther, George T. Shubeita. Seoul, South Korea. Center for Nonlinear Dynamics and Department of Physics,

Institute for Cellular and Molecular Biology, The University of 73 - 6:00 Texas at Austin, Austin, Tx 78712. Metabolic pathways contributing to increased longevity in

Drosophila. Lauren A. Reynolds, Kimberly A. Hughes. Biology, 82 - 6:15 Florida State University, Tallahassee, FL. Light-induced elimination of protein function in vivo. Dave Stein.

Department of Molecular Biosciences, University of Texas, 74 - 6:15 Austin, TX. Or22a and Or22b Are Both Involved in the Regulation of Fruit Fly Longevity. Ceyda Bilgir1, Xiowen Chu2, Scott Pletcher1. 1) Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI; 2) Huffington Center on Aging, Baylor College of Medicine, Houston, TX.

CONCURRENT PLATFORM SESSIONS FRIDAY, MARCH 28 4:30-6:30 PM Presenting author is in bold. Full abstracts can be found online.

90 - 6:15 RNA Biology Ribosomal protein RACK1 is a specific host factor required for IRES-mediated translation of fly and human viruses. Carine Meignin1, Karim Majzoub1, Mohamed Lamine Hafirassou2, Co-Moderators: Susan Celniker, Lawrence Berkeley National Stefano Marzi3, Franck Martin3, Thomas Baumert2, Catherine Laboratory, California and Paul Lasko, McGill University, Schuster2, Jean-Luc Imler1. 1) IBMC UPR9022, University of Montreal, Canada Strasbourg, Strasbourg, France; 2) UMR 1110, University of

Strasbourg, Strasbourg, France Institut de Virologie; 3) IBMC Room: California UPR9002, University of Strasbourg, Strasbourg, France.

83 - 4:30 Diversity and Dynamics of the Drosophila Transcriptome. James B. Brown, The Celniker modENCODE Transcription Consortium. Notes Genome Dynamics, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA.

84 - 4:45 Suppressor of sable [Su(s)] and its partner Wdr82 promote the production of short unstable RNAs from Hsp70-αβ elements. Lillie L. Searles1,2, Paul Brewer-Jensen1, Lonna Mollison2, Carrie B. Wilson1, John Abernethy1, Samantha Card1. 1) Dept Biol, Univ North Carolina, Chapel Hill; 2) Curriculum in Genetics and Mol Biol, Univ North Carolina, Chapel Hill.

85 - 5:00 Smg5 is critical for multiple NMD pathways. Jonathan O. Nelson1, Dominique Förster2, Stefan Luschnig2, Mark M. Metzstein1. 1) Human Genetics, Univ of Utah, Salt Lake City; 2) IMLS, Univ of Zurich, Switzerland.

86 - 5:15 Unusual origin of Drosophila RNase P RNA from the intron of a pol II-regulated transcript. Sathiya Narayanan Manivannan1, Lien Lai2, Venkat Gopalan1,2,3, Amanda Simcox1,3. 1) Molecular Cellular Developmental Biology program, Ohio State Univ, Columbus; 2) Dept of Chemistry and Biochemistry, Ohio State Univ, Columbus; 3) Dept of Molecular Genetics, Ohio State Univ, Columbus.

87 - 5:30 Regulated stop codon readthrough yields C-terminal protein extensions in Drosophila melanogaster. Joshua G. Dunn1,2,3,4, Catherine K. Foo1,2,3, Nicolette G. Belletier5, Elizabeth R. Gavis5, Jonathan S. Weissman1,2,3,4. 1) Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, CA; 2) California Institute of Quantitative Biosciences, San Francisco, CA; 3) Howard Hughes Medical Institute, UCSF; 4) Center for RNA Systems Biology, UCSF and University of California, Berkeley, CA; 5) Department of Molecular Biology, Princeton University, NJ.

88 - 5:45 IRES-Mediated Translation of grk mRNA During Drosophila Oogenesis. Jacob A. Merle, Danielle E. Hindes, Malachi A, Blundon, Maya D. Mills, Matthew A. Fountain, Scott B. Ferguson. Departments of Biology, Chemistry and Biochemistry, SUNY Fredonia, Fredonia, NY.

89 - 6:00 piRNAs and epigenetic conversion in Drosophila . Catherine Hermant, Antoine Boivin, Laure Teysset, Augustin de Vanssay, Valérie Delmarre, Christophe Antoniewski, Stephane Ronsseray. Laboratoire de Biologie du Développement- UMR7622-CNRS- Université Pierre Marie Curie, Paris.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 8:30-10:15 AM Presenting author is in bold. Full abstracts can be found online.

Cell Biology and Signal Transduction Drosophila Models of Human Disease I

Co-Moderators: Christian Böekel, Technische Universitat, Co-Moderators: Tian Xu, Yale University, New Haven, Dresden, Germany and Esther Verheyen, Simon Fraser University, Connecticut and Bing Zhang, University of Missouri, Columbia Burnaby, Canada Room: Golden West Room: Town & Country 98 - 8:30 Role of the microbiota in a Drosophila model of intestinal barrier 91 - 8:30 dysfunction. Rebecca Clark, David Walker. Dept. of Integrative Calpain A regulates NFkappaB function during embryogenesis and Biology and Physiology, UCLA, Los Angeles, CA. the immune response by limited Cactus proteolysis. Marcio Fonetenele1,2, Maira Cardoso1, Bomyi Lim4, Daniela Oliveira1, 99 - 8:45 David Perlman3, Trudi Schupbach3,5, Helena Araujo1,2. 1) Institute The formation of Hopscotch-induced hemocyte tumors requires the for Biomedical Sciences, Fed Univ Rio de Janeiro, Rio de Janeiro, JAK/STAT transcriptional target Gα73B. Martin P. Zeidler, Nina Brazil; 2) National Institute for Molecular Entomology - Bausek. Biomedical Science, The University of Sheffield, INCT/INEM, Brazil; 3) Molecular Biology Department, Princeton Sheffield, United Kingdom. University; 4) Lewis Sigler Institute for Integrative Genomics, Princeton University; 5) Howard Hughes Medical Institute. 100 - 9:00 The Transposon Storm Hypothesis of Neurodegeneration. Joshua 92 - 8:45 T. Dubnau1, Nabanita Chatterjee1, Rebeca Borges1,2, Lisa Krug1,3, GTPase Regulatory Proteins control Organ Size through Hippo Lisa Prazak1, Will Donovan1,3, Anais Julien1,4. 1) Cold Spring Signalling. Lucas G. Dent1,2, Kieran F. Harvey1. 1) Cell Growth Harbor Lab, Cold Spring Harbr, NY; 2) The Undergraduate and Proliferation Laboratory, Peter MacCallum Cancer Centre, Program on Genomic Sciences of the Nacional Autonomous Melbourne, VIC, Australia; 2) Pathology, University Of University of Mexico; 3) Watson School of Biological Sciences, Melbourne, Melbourne, VIC, Australia. Cold Spring Harbor Laboratory; 4) Magistère de Génétique Graduate Program at Université Paris Diderot, Sorbonne Paris 93 - 9:00 Cité, France. Cytoneme-mediated contact-dependent transport of the Drosophila Decapentaplegic signaling protein. Sougata Roy, Hai Huang, 101 - 9:15 Thomas B. Kornberg. Cardiovascular Research Institute, Regulatory Network in Diet-induced Obesity and Lipotoxic University of California San Francisco, San Francisco, CA. Cardiomyopathy. Soda Diop, Rolf Bodmer. Development and Aging Program, Sanford Burnham Medical Research Institute, La 94 - 9:15 Jolla, CA. ERK interactome perturbations induced by mutations of docking domains. Liu Yang1, Alan Futran2, A. James LInk2, Stanislav Y. 102 - 9:30 Shvartsman2, Alexey Veraksa1. 1) Biology, UMass Boston, TDP-43 neurotoxicity is modulated by Fragile X Protein and Boston, MA; 2) Chemical and Biological Engineering, Princeton Futsch in a Drosophila model of Amyotrophic Lateral Sclerosis. University, Princeton, NJ. Alyssa Coyne1,2,3, Shizuka Yamada1,2,3, Patricia Estes1,2,3, Donovan Lockwood1,2,3, Michael Hart4, Brian Freibaum5, Joel Cassel6, Allen 95 - 9:30 Reitz6, J. Paul Taylor5, Aaron Gitler4, Daniela Zarnescu1,2,3. 1) A novel Talin-dependent mechanism mediates clustering of Department of Molecular and Cellular Biology, University of integrin adhesion receptors to reinforce tissue architecture. Emily Arizona, Tucson, AZ; 2) Department of Neuroscience, University E. Lostchuck1, Stephanie J. Ellis1, Benjamin T. Goult2, Mohamed of Arizona, Tucson, AZ; 3) Department of Neurology, University Bouaouina3, Michael J. Fairchild1, David A. Calderwood3, Guy of Arizona, Tucson, AZ; 4) Department of Genetics, Stanford Tanentzapf3. 1) Cell and Physiological Sciences, University of University, Stanford, CA; 5) Department of Neurobiology, St. Jude British Columbia, Vancouver, British Columbia, Canada; 2) Dept. Children's Research Hospital, Memphis, TN; 6) ALS Biopharma of Biochemistry, University of Leicester; 3) Dept. of LLC, Philadelphia, PA. Pharmacology, Yale University School of Medicine. 103 - 9:45 96 - 9:45 Investigating Resistance and Tolerance to Cancer. Adler R. The surprising case of Wingless or how not to be a morphogen. Dillman, David S. Schneider. Microbiology and Immunology, Luis Alberto Baena-Lopez, Cyrille Alexandre, Jean-Paul Stanford, Stanford, CA. Vincent. Developmental Biology, NIMR. MRC. London, United Kingdom. 104 - 10:00 Flies and humans with prickle mutations exhibit similar epilepsy 97 - 10:00 syndromes. Salleh Ehaideb1,2, Atulya Iyengar2, Katie Cranston2, Mechanisms of Notch-Src synergy in Drosophila. Diana M. Ho, Alexander G. Bassuk3, David Gubb4, Chun-Fang Wu2, J. Robert S. K. Pallavi, Spyros Artavanis-Tsakonas. Dept. of Cell Biology, Manak1,2,3. 1) Interdisciplinary Graduate Program in Genetics, Harvard Medical School, Boston, MA. University of Iowa, Iowa City, IA; 2) Department of Biology, University of Iowa, Iowa City, IA; 3) Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA; 4) Centre National de la Recherche Scientifique, Institut de Biologie Moléculaire et Cellulaire, Strasbourg Cedex, France.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 8:30-10:15 AM Presenting author is in bold. Full abstracts can be found online.

Regulation of Gene Expression I Notes

Co-Moderators: Michael Levine, University of California, Berkeley and Lori Pile, Wayne State University, Detroit, Michigan

Room: California

105 - 8:30 Genome-wide binding of K50 family transcription factors. Rhea R. Datta1, Jia Ling1, Leila Shokri2, Anastasia Vedenko2, Martha L. Bulyk2, Steve Small1. 1) Dept of Biology, New York Univ; 2) Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA.

106 - 8:45 Co-option of a Hox-regulated network underlies a morphological novelty in Drosophila melanogaster. Mark Rebeiz, William Glassford, Chas Elliot, Winslow Johnson. Biological Sciences, University of Pittsburgh, PIttsburgh, PA.

107 - 9:00 A simple model of gradient interpretation can explain the precise pattern of even skipped in the Drosophila embryo. Garth R. Ilsley1, Jasmin Fisher2,3, Rolf Apweiler4, Angela H. DePace5, Nicholas M. Luscombe1,6,7. 1) Okinawa Inst of Science and Technology Graduate Univ, Japan; 2) Microsoft Research Cambridge, UK; 3) Dept of Biochemistry, Univ of Cambridge, UK; 4) European Molecular Biology Laboratory, European Bioinformatics Inst, Wellcome Trust Genome Campus, UK; 5) Dept of Systems Biology, Harvard Medical School, Boston, MA; 6) UCL Genetics Institute, Dept of Genetics, Evolution and Environment, Univ College London, UK; 7) London Research Inst, Cancer Research UK.

108 - 9:15 Zelda potentiates morphogen binding in the early embryo. Sun Melody Foo1, Yujia Sun1, Bomyi Lim2,3, Kai Chen4, Ruta Ziukaite1, Julia Zeitlinger4, Stanislav Shvartsman2,3, Christine Rushlow1. 1) Dept of Biology, New York; 2) Dept of Chemical and Biological Engineering, Princeton University, NJ; 3) Lewis- Sigler Inst for Integrative Genomics, Princeton Univ, Princeton, NJ; 4) Stowers Inst for Medical Research, Kansas City, MO.

109 - 9:30 Spatial expression of a comprehensive set of Drosophila transcription factors reveals novel insights into regulatory networks. Erwin Frise1, Ann Hammonds1, Siqi Wu1,2, Antony Joseph1,2, Richard Weiszmann1, William Fisher1, Bin Yu2, Susan Celniker1. 1) BDGP/Genome Dynamics, Lawrence Berkeley National Labs, Berkeley, CA; 2) Dept. of Statistics, UCB, Berkeley, CA.

110 - 9:45 Direct Quantification of Transcriptional Regulation at an Endogenous Gene Locus. Heng Xu1,3, Anna Sokac1, Ido Golding1,2,3. 1) Dept of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX; 2) Center for Theoretical Biological Physics, Rice Univ, Houston, TX; 3) Center for the Physics of Living Cells, Univ of Illinois at Urbana- Champaign.

111 - 10:00 Characterizing the dynamics of Yan polymerization, DNA binding and transcriptional repression during RTK-regulated cell fate transitions. Jean-Francois Boisclair Lachance1,3, Nicolás Peláez2,3, Arnau Gavalda2,3, Luís Amaral2,3, Richard Carthew2,3, Ilaria Rebay1,3. 1) University of Chicago; 2) Northwestern University, Evanston, IL; 3) Chicago Center for Systems Biology.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 10:45 AM-12:30 PM Presenting author is in bold. Full abstracts can be found online.

Organelles and Trafficking Drosophila Models of Human Disease II

Moderator: Tina Tootle, University of Iowa, Iowa City Co-Moderators: Gabrielle Boulianne, Hospital for Sick Children, Toronto, Canada and John Manak, University of Iowa, Iowa City Room: Town & Country Room: Golden West 112 - 10:45 Abl/Enabled signaling regulates Golgi architecture in vivo. 119 - 10:45 Ramakrishnan Kannan, Irina Kuzina, Joy Gu, Edward Giniger. A novel gene, SAD, is required for axonal integrity in aging - a National Inst of Neurological Disorder and Stroke, National discovery from an unbiased genetic screen using the Drosophila Institute of Health, Bethesda, MD. wing as a model. Yanshan Fang1, Xu Cao1, Xiuyin Teng2, Qinqin Li1, Yongqing Zhu2, Nancy Bonini2. 1) SIOC, IRCBC, Chinese 113 - 11:00 Academy of Sciences, Shanghai, China; 2) HHMI, Univ of Clathrin-mediated endocytosis promotes embryonic wound repair Pennsylvania, Philadelphia, PA. in Drosophila. Miranda V. Hunter1, Rodrigo Fernandez- Gonzalez1,2,3. 1) Department of Cell and Systems Biology, 120 - 11:00 University of Toronto, Toronto, Ontario, Canada; 2) Institute of Quantification of Drosophila insulin reveals genetic mechanisms Biomaterials and Biomedical Engineering, University of Toronto, of human diabetes risk. Sangbin Park, Ronald W. Alfa, Sydni M. Toronto, Ontario, Canada; 3) Developmental and Stem Cell Topper, Grace E. S. Kim, Lutz Kockel, Seung K. Kim. Biology Program, The Hospital for Sick Children, Toronto, Developmental Biology, Stanford University School of Medicine, Ontario, Canada. Standford, CA.

114 - 11:15 121 - 11:15 Kelch functions as a ubiquitin E3 ligase required for ovarian ring Common responses of Drosophila and mammalian cells to novel canal growth. Andrew Hudson, Lynn Cooley. Dept Genetics, lipid-lowering drugs. Kseniya Golovnina1, Kirsten Tschapalda2,3, Yale Univ Sch Medicine, New Haven, CT. Zhuyin Li4, Min Shen4, Matthew Boxer4, Brian Oliver1, Mathias Beller2. 1) NIH/NIDDK, Bethesda, MD; 2) Institute for 115 - 11:30 Mathematical Modeling of Biological Systems, Heinrich Heine An AP-1-dependent E-Cadherin recycling defect reveals a role for University, Düsseldorf, Germany; 3) Department of Chemical E-Cadherin in ring canals anchoring in Drosophila germline cysts. Biology, Max Planck Institute of Molecular Physiology, Nicolas Loyer, Irina Kolotuev, Roland Le Borgne. IGDR, Rennes, Dortmund, Germany; 4) NIH/NCATS, Rockville, MD. France. 122 - 11:30 116 - 11:45 Exploiting Drosophila as a platform to develop anti-amyloid Mitotic Spatial Organization and Structural Morphology of the strategies. Pedro Fernandez-Funez1,2, Jonantan Sanchez-Garcia1, Endoplasmic Reticulum are Independently Regulated. Zane J. Swati Khare1, Alfonso Martin-Peña1, Diego Rincon-Limas1,2. 1) Bergman, Justin D. Mclaurin, Blake Riggs. Biology, San Dept Neurology, Univ Florida, Gainesville, FL; 2) McKnight Francisco State University, San Francisco, CA. Brain Institute, Genetics Institute, and Center for Translational Research on Neurodegenerative Disorders. 117 - 12:00 Rab GTPases and BMP signalling regulate exosome secretion by 123 - 11:45 controlling distinct endolysosomal trafficking events in Drosophila H+ Efflux Enables Cancer Cell Behaviors. Bree K. Grillo-Hill, secondary cells. Siamak Redhai, Laura Corrigan, Aaron Leiblich, Mario Esquivel, Diane L. Barber. Cell and Tissue Biology, Univ Shih-Jung Fan, Mark Wainwright, Carina Gandy, Sumeth Perera, California, San Francisco, San Francisco, CA. Deborah Goberdhan, Clive Wilson. Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United 124 - 12:00 Kingdom. Characterization of the leukemogenesis activity of the human Nup98-HoxA9 oncoprotein using Drosophila as a model system. 118 - 12:15 Gwenaelle Gavory, Caroline Baril, Gawa Bidla, Marc Therrien. Fbxl7 is an F-box protein that functions with the atypical cadherin IRIC, University of Montreal, Montreal, Quebec, Canada. Fat to control tissue size and shape. Justin A. Bosch, Taryn Sumabat, Kevin Gandhi, Iswar K. Hariharan. Molecular and Cell 125 - 12:15 Biology, University of California - Berkeley, Berkeley, CA. Mitochondrial i-AAA protease deficiency leads to neuromuscular degeneration through apoptotic cell death. Yun Qi, Hong Xu. GDBC, NHLBI, Bethesda, MD.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 10:45 AM-12:30 PM Presenting author is in bold. Full abstracts can be found online.

Gene Expression and Chromatin II Notes

Moderator: Maya Capelson, University of Pennsylvania, Philadelphia

Room: California

126 - 10:45 A new paternal effect lethal is required to prime paternal chromatin for embryonic mitosis. Mia T. Levine1, Helen M. Vander Wende1, Harmit S. Malik1,2. 1) Division of Basic Sciences, Fred Hutchinson Cancer Research Center Seattle, WA; 2) HHMI.

127 - 11:00 The Epigenome of Evolving Drosophila Neo-Sex Chromosomes: Dosage Compensation and Heterochromatin Formation. Qi Zhou1, Chris Ellison1, Vera Kaiser1, Artyom Alekseyenko2, Andrey Gorchakov2,3, Doris Bachtrog1. 1) Integrative Biology, University of California, Berkeley, Berkeley, CA; 2) Department of Genetics, Harvard Medical School; 3) Institute of Molecular and Cellular Biology, Novosibirsk, Russia.

128 - 11:15 The weak shall lead the strong: Low-affinity transcription factor binding sites in morphogen gradient responses and enhancer evolution. David Lorberbaum1,2, Andrea Ramos1,2, Victoria Blake1, Charles Katzman1, David Parker1, Christina Swanson1,3, Scott Barolo1,2. 1) Dept. of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, MI; 2) Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, MI; 3) Current address: Dept. of Biology, UNC Chapel Hill, NC.

129 - 11:30 Analysis of transcription factors binding footprints at developmental enhancers using ChIP-nexus, a novel ChIP-exo protocol. Qiye He1, Jeff Johnston1, Julia Zeitlinger1,2. 1) Stowers Institute for Medical Research, Kansas City, MO; 2) The University of Kansas School of Medicine, Department of Pathology and Laboratory Medicine, Kansas City, KS.

130 - 11:45 K27me3 and CTCF demarcate cis-regulatory domains in the Drosophila bithorax complex. Sarah K. Bowman1,2, Aimee M. Deaton1,2, Peggy Wang1, Heber Domingues3, Robert E. Kingston1,2, Welcome Bender3. 1) Massachusetts General Hospital, Dept. of Molecular Biology, Boston, MA; 2) Harvard Medical School, Dept. of Genetics, Boston, MA; 3) Harvard Medical School, Dept. of Biological Chemistry and Molecular Pharmacology, Boston, MA.

131 - 12:00 Intrinsically random decisions and interchromosomal communication control stochastic expression in the fly eye. Robert J. Johnston. Department of Biology, Johns Hopkins University, Baltimore, MD.

132 - 12:15 The function of Zelda in establishing early embryonic genome organization. Katharine N. Schulz1, Daniel J. McKay2, Danielle C. Hamm1, Jason D. Lieb3, Melissa M. Harrison1. 1) Dept. of Biomolecular Chemistry, University of Wisconsin, Madison, WI; 2) Dept. of Biology, The University of North Carolina, Chapel Hill, NC; 3) Dept. of Molecular Biology, Princeton University, Princeton, NJ.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 4:00-6:00 PM Presenting author is in bold. Full abstracts can be found online.

Immunity and Pathogenesis Neurophysiology and Behavior

Co-Moderators: Sara Cherry, University of Pennsylvania, Co-Moderators: Chi-Hon Lee, National Institute of Child Health Philadelphia and Rui Zhou, Sanford-Burnham Medical Research and Human Development, NIH, Bethesda, Maryland and Noreen Institute, San Diego, California Reist, Colorado State University, Fort Collins

Room: Town & Country Room: Golden West

133 - 4:00 141 - 4:00 PVR controls the antiviral ERK pathway in the Drosophila gut. Taste of fatty acids - a new modality in Drosophila. Pavel Masek, Christine L. Sansone, Jie Xu, Ari Yasunaga, Beth Gordesky- Alex Keene. Biology Department, University of Nevada Reno, Gold, Sara Cherry. Microbiology, University of Pennsylvania, Reno, NV. Philadelphia, PA. 142 - 4:15 134 - 4:15 Acoustic Duetting During Courtship in Drosophila virilis. Kelly Epigenetic regulation of the antiviral Jak-Stat pathway by the M. LaRue1,2, Gordon J. Berman1,3, Tristan Perez1,2, Georgia histone methyltransferase G9a in Drosophila. Sarah Merkling, Guan1,2, David L. Stern4, Mala Murthy1,2. 1) Molecular Biology, Walter Bronkhorst, Gijs Overheul, Jamie Kramer, Annette Princeton University, Princeton, NJ; 2) Princeton Neuroscience Schenck, Ronald van Rij. Radboud University Nijmegen Medical Institute, Princeton University, Princeton, NJ; 3) Lewis Sigler Center, Nijmegen Institute for Molecular Life Sciences, Nijmegen, Institute for Integrative Genomics, Princeton University, Princeton, The Netherlands. NJ; 4) Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA. 135 - 4:30 Extracellular adenosine regulates complex host-pathogen 143 - 4:30 interactions through the energy release for the immune response. Genetic and molecular bases of noxious cold detection in Tomas Dolezal1,2, Adam Bajgar2, Katerina Kucerova2, Lucie Drosophila larvae. Kevin Armengol1, Heather Turner2, Srividya Jonatova2, David Schneider1. 1) Microbiology and Immunology, C. Iyer1, Luis Sullivan1, Eswar P. R. Iyer1, Christian Landry2, Stanford University School of Medicine, Stanford, CA; 2) Faculty Michael J. Galko2, Daniel N. Cox1. 1) Krasnow Institute, School of of Science, University of South Bohemia in Ceske Budejovice, Systems Biology, George Mason University, Fairfax, VA; 2) Dept. Czech Republic. of Biochemistry & Molecular Biol, Dept. of Genetics, UT MD Anderson Cancer Center, Houston, TX. 136 - 4:45 Drosophila-associated microbes promote host protein metabolism 144 - 4:45 to rescue lifespan and development during malnutrition. Ryuichi Translational profiling of clock cells reveals circadianly Yamada, William Ja. Metabolism and Aging, The Scripps synchronized protein synthesis. Yanmei Huang, Joshua Ainsley, Research Institute, Jupiter, FL. Leon Reijmers, F. Rob Jackson. Department of Neuroscience, Tufts University School of Medicine, Boston, MA. 137 - 5:00 The serine protease homolog novi is involved in sensing of 145 - 5:00 pathogenic Gram positive bacteria. Jelena Patrnogic, Vincent Synaptic microcircuits control Drosophila sleep and arousal. Divya Leclerc, Jean-Marc Reichhart. Institut de Biologie Moléculaire et Sitaraman1,2, Yoshinori Aso2, Gerald Rubin2, Michael Nitabach1,2. Cellulaire, CNRS UPR9022, 15 rue René Descartes, Strasbourg, 1) Yale University School of Medicine, New Haven, CT; 2) Janelia France. Farm Research Campus, HHMI Ashburn, VA.

138 - 5:15 146 - 5:15 Origin, anatomy and proliferative capacity of adult hemocytes in Serotonin motivates feeding behavior and appetitive memory Drosophila. Kalpana Makhijani1, Brandy Alexander1, Christa performance in Drosophila. Stephanie D. Albin1, Karla R. Rhiner4, Eduardo Moreno4, Katja Brückner1,2,3. 1) Dept. Cell and Kaun1,2, Phuong Chung1, Jon-Michael Knapp1, Ulrike Heberlein1, Tissue Biology; 2) Broad Center of Regeneration Medicine and Julie H. Simpson1. 1) HHMI Janelia Farm, Ashburn, VA; 2) Stem Cell Research; 3) CVRI; University of California San Brown University, Providence, RI. Francisco, CA; 4) University of Bern, Switzerland. 147 - 5:30 139 - 5:30 A novel high-throughput mechanical nociception paradigm Protein restriction enhances anti-bacterial immunity through Target suggests a role for neuropeptides in nociception behavior. W. D. of Rapamycin and posttranslational regulation of Myc by protein Tracey, Melissa Gottron, Ken Honjo. Dept Anesthesiology, Duke phosphatase 2A. Jung-Eun Lee, Scott Pletcher. University of Univ Med Ctr, Durham, NC. Michigan, Ann Arbor, MI. 148 - 5:45 140 - 5:45 Drosophila larvae establish a radish-dependent anesthesia resistent Cholera toxin disrupts intestinal epithelial integrity by inhibiting memory after aversive olfactory conditioning. Annekathrin junctional transport. Annabel E. Guichard1, Beatriz Cruz Widmann, Andreas Thum. Biology, University, Konstanz, Moreno1, Berenice Aguilar2, Nina van Sorge2, Jennifer Kuang1, Germany. Adrianne Kurkciyan1, Zhipeng Wang4, Saiyu Hang4, Guillaume Pineton de Chambrun3, Declan McCole3, Paula Watnick4, Victor Nizet2, Ethan Bier1. 1) Dept Biology, Univ California, San Diego, La Jolla, CA; 2) Dept Pediatrics, Univ California, San Diego, La Jolla, CA; 3) Dept Medicine, Univ California, San Diego, La Jolla, CA; 4) Children's Hospital, Boston, MA 02115.

CONCURRENT PLATFORM SESSIONS SATURDAY, MARCH 29 4:00-6:00 PM Presenting author is in bold. Full abstracts can be found online.

Stem Cells Notes

Co-Moderators: Michael Buszczak, UT Southwestern, Dallas, Texas and Volker Hartenstein, University of California, Los Angeles

Room: California

149 - 4:00 dFezf/Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors. Derek Janssens1, Hideyuki Komori2, Daniel Grbac2, Cheng-Yu Lee2,3,4. 1) Program in Cellular and Molecular Biology; 2) Life Sciences Institute; 3) Department of Internal Medicine; 4) Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.

150 - 4:15 Neuroblasts transiently express differentiation factor Prospero in nucleus during entry into quiescence. Sen-Lin Lai1,3, Chris Q. Doe1,2,3. 1) HHMI; 2) Institute of Molecular Biology; 3) Institute of Neuroscience, University of Oregon, Eugene, OR 97403.

151 - 4:30 Notch signaling and FoxA collaborate to maintain intestinal stem cells in Drosophila adult midgut. Qing Lan, Min Cao, Huaqi Jiang. Developmental Biology, UT Southwestern Medical Center, Dallas, TX.

152 - 4:45 Somatic mutation drives genetic heterogeneity and spontaneous neoplasia in the aging intestine. Katarzyna Siudeja, Patricia Skorski, Allison Bardin. Genetics and Developmental Biology Unit, Institut Curie, Paris, France.

153 - 5:00 Muscle niche ensures survival and reactivation of dormant Adult Muscle Precursors in Drosophila. Krzysztof Jagla, Rajaguru Aradhya. GReD, INSERM U1103, CNRS UMR6293, Clermont- Ferrand, France.

154 - 5:15 EGFR Regulates Epithelial Follicle Stem Cell Polarity to Facilitate Asymmetric Division. Angela Castanieto, Todd Nystul. University of California San Francisco, San Francisco, CA.

155 - 5:30 Wnt signaling in escorts cells regulate germ cell differentiation in drosophila ovary. Su Wang1,2, Ting XIe1,2. 1) Xie's Lab, Stowers Inst Medical Research, Kansas City, MO; 2) University of Kansas Medical Center, Department of Anatomy and Cell biology, Kansas City, KS.

156 - 5:45 An insulin-independent requirement for the adiponectin receptor homolog in the maintenance of Drosophila melanogaster germline stem cells. Kaitlin Laws1, Leesa Sampson1, Daniela Drummond- Barbosa1. 1) Department of Biochemistry and Molecular Biology; Johns Hopkins Bloomberg School of Public Health; Baltimore, MD; .

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

POSTER LEGEND

Cell Biology and Cytoskeleton ...... 157A-215B

Cell Biology and Signal Transduction ...... 216C-259A

Cell Cycle and Death ...... 260B-277A

Cell Division and Growth Control ...... 278B-317B

Physiology, Organismal Growth, and Aging ...... 318C-369C

Gametogenesis and Organogenesis ...... 370A-414C

Stem Cells ...... 415A-447C

Immunity and Pathogenesis ...... 448A-466A

Neural Development ...... 467B-495C

Neurophysiology and Behavior ...... 496A-540C

Drosophila Models of Human Diseases ...... 541A-625A

Evolution and Quantitative Genetics ...... 626B-703A

Pattern Formation ...... 704B-722B

Regulation of Gene Expression ...... 723C-774C

Chromatin and Epigenetics ...... 775A-824B

RNA Biology ...... 825C-850A

Techniques and Resources ...... 851B-885C

Educational Initiatives ...... 886A-891C

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Cell Biology and Cytoskeleton 168C Molecular dissection of the PINCH-RSU1 interaction in Drosophila. Julie L. Kadrmas1,2, Stephen M. Pronovost1. 1) Huntsman Cancer Institute; 2) Oncological Sci, Univ Utah, Salt 157A Lake City, UT. The role of Orc6 in septin complex functions in Drosophila. Katarina Akhmetova1,2, Maxim Balasov1, Richard Huijbregts1, 169A Igor Chesnokov1. 1) Biochemistry and Molecular Genetics, UAB, Flapwing may Function with Ena during Head Involution and Birmingham, AL; 2) Institute of Cytology and Genetics, Dorsal Closure. Rebecca LeShay, Julie Gates. Biology Dept., Novosibirsk, Russia. Bucknell University, Lewisburg, PA.

158B 170B Tubulation and furrow ingression during epithelial formation is Identifying a Kelch-Cullin3 ubiquitin ligase substrate. Katelynn directed by Rab8. J. Todd Blankenship, Lauren Mavor, Zach M. Mannix, Andrew Hudson, Lynn Cooley. Genetics Dept., Yale Zuo. Biological Sciences, University of Denver, Denver, CO. University, New Haven, CT.

159C 171C NMNAT Regulates Neuronal Microtubule Assembly State. The role of microtubule-based motor proteins in Drosophila bristle Jennifer M. Brazill, Brandon M. Kitay, Yousuf O. Ali, R. Grace development. Anna Melkov, Yasmin Simchoni, Anna Bakhart, Zhai. Molecular and Cellular Pharmacology, University of Miami Uri Abdu. Ben Gurion University, Israel, Beer Sheva, Israel. Miller School of Medicine, Miami, FL. 172A 160A Asymmetric distribution of the homophilic cell surface molecule Functions of tropomyosin in vivo. Aeri Cho, Denise Montell. Echinoid polarizes the actin cytoskeleton. Arsida Nocka, Laura University of California, Santa Barbara, Santa Barbara, CA. Nilson. Biology Department, McGill University, Montreal, Quebec, Canada. 161B Drak is required for actomyosin assembly or organization during 173B Drosophila cellularization. Ashish B. Chougule1, Mary Catherine Epithelial Cell Alignment: A model of concerted cell shape Hastert2, Jeffrey H. Thomas1. 1) Cell Biology and Biochemistry, changes. Katy Lauren Ong, Stephen DiNardo. Cell and TTUHSC, Lubbock, TX; 2) Biological Sciences Imaging Center, Developmental Biology, University of Pennsylvania, Philadelphia, TTU, Lubbock, TX. PA.

162C 174C Ena and Dynein Light Chain 90F may Function Together during The conserved transmembrane proteoglycan Perdido/Kon-tiki is 1 Head Involution. Brittany Duran, Julie Gates. Biology Dept., essential for myofibrillogenesis. Juan José Pérez-Moreno , 2 1 Bucknell University, Lewisburg, PA. Marcus Bischoff , María Dolores Martín-Bermudo , Beatriz 1 Estrada . 1) Centro Andaluz de Biología del Desarrollo 163A (CSIC/UPO), Seville, Spain; 2) Biomolecular Sciences Building, Garz may Function with Ena During Epithelial Morphogenesis. University of St Andrews, Scotland, UK. Rachel Franz, Julie Gates. Biology Dept., Bucknell University, Lewisburg, PA. 175A Ovhts-RC modulates cytoplasmic actin filaments in developing 164B oocytes. Nancy J. Pokrywka. Dept of Biology, Vassar College, Presenilin and GSK-3β control motor-cargo movement on Poughkeepsie, NY. microtubules. Kunsang Dolma, Gary Iacobucci, Kan Hong Zheng, Joseph White, Shermali D. Gunawardena. Biological Sciences, 176B SUNY at Buffalo, Buffalo, NY. The role for Spire in phosphoinositide-regulated hemocyte membrane trafficking and cortical remodeling. Anette 165C Pykalainen, Amy Kiger. Biology, University of California, San Integrin regulation of filopodia during muscle migration. Yoshiko Diego, 9500 Gilman Dr., La Jolla, 92093 CA. Inoue1,3, Jenny Gallop1,3, Nicholas Brown1,2. 1) The Gurdon Institute, Cambridge, United Kingdom; 2) Dept. of Biochemistry, 177C University of Cambridge; 3) Dept. of PDN, University of The role of ER-specific proteins reticulon, lunapark, and atlastin in Cambridge. the early Drosophila melanogaster embryo. Amanda M. Sims, Rachel Coombs, Blake Riggs. San Francisco State University 1600 166A Holloway Avenue San Francisco, CA 94132. A genetic screen to identify dominant modifiers of Abl signaling during cell migration. Megan Jackson, Kristina M. Reiss, 178A Christopher S. Moline, Traci L. Stevens. Biology, Randolph- Coordination of Rho family GTPase activities to orchestrate Macon College, Ashland, VA. cytoskeleton responses during cell wound repair. Jeffrey M. Verboon, Maria Abreu-Blanco, Susan Parkhurst. Fred Hutchinson 167B Cancer Research Institute, Seattle, WA. Exploring the role of α-Actinin and Cheerio during Ventral Furrow Invagination and Dorsal Closure. Jaime Jurado-Gomez1, Michael 179B Tworoger2, Adam C. Martin2, Nicole Gorfinkiel1. 1) Centro Coordinating the pulsed and ratcheted contractions that drive Biologia Molecular 'Severo Ochoa', Madrid, Spain; 2) Department collective apical constrictions during Drosophila gastrulation. 1 2 of Biology, Massachusetts Institute of Technology, Cambridge, Shicong Xie , Adam Martin . 1) PhD program in Computational & Massachusetts, USA. Systems Biology, Massachusetts Institute of Technology,

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Cambridge, MA; 2) Department of Biology, Massachusetts 190A Institute of Technology, Cambridge, MA. A genetic screen identifies Rab35 and membrane trafficking regulators that control Transverse-tubule membrane remodeling 180C required for muscle function. Naonobu Fujita, Wilson Huang, PIP2 regulates stability of cleavage furrow-associated proteins Amy Kiger. Section of Cell and Developmental Biology, UCSD, during cytokinesis. Sukriye Yildirim1, Lacramioara Fabian1, San Diego, CA. Raymond Wong1,2, Ho-Chun Wei1, Gordon Polevoy1, Julie A. Brill1,2,3. 1) CELL BIOLOGY PROGRAM, THE HOSPITAL FOR 191B SICK CHILDREN; 2) INSTITUTE OF MEDICAL SCIENCE, Rabs and Vacuoles : The role of Abd-B in male accessory glands UNIVERSITY OF TORONTO; 3) DEPARTMENT OF trafficking. Elodie Prince1, Marko Brankatschk2, Dragan MOLECULAR GENETICS, UNIVERSITY OF TORONTO. Gligorov1, Robert K. Maeda1, Suzanne R. Eaton2, François Karch1. 1) Genetics & Evolution, University of Geneva, GENEVA, GE, 181A Switzerland; 2) Max Planck Institute of Molecular Cell Biology The Role of the Drosophila Formin Frl in the Establishment of and Genetics, Dresden, Germany. Planar Cell Polarity. Austen A. Barnett1, Saw-Myat Maung1, Gretchen Dollar1, Cathie Pfleger2, Andreas Jenny1. 1) Molecular 192C and Developmental Biology, Albert Einstein College of Medicine, Egalitarian links oskar mRNA to motor complexes in Drosophila Yeshiva University, New York, NY; 2) Department of Oncological oocyte. Paulomi B. Sanghavi1, Caryn Navarro2, Graydon Sciences, Icahn School of Medicine, Mt. Sinai Hospital, New Gonsalvez1. 1) Cellular Biology and Anatomy, Georgia Regents York, NY. University, Augusta, GA; 2) Biomedical Genetics Boston University School of Medicine, Boston, MA 02118. 182B The polarity protein aPKC physically interacts with Nuf regulating 193A vesicle trafficking. Francisco J. Calero, Sol Sotillos. CABD, The role of N-Cadherin in myoblast adhesion and its regulation Seville (Spain). during fusion. Carina Braukmann1, Christine Dottermusch- Heidel1, Verena Groth2, Julia Hamp1, Marco Rust3, Susanne-Filiz 183C Önel1. 1) Developmental Biology, Philipps Universität Marburg, Structure-function analysis of Crumbs. Shradha Das, Elisabeth Marburg, Hessen, Germany; 2) Christian-Albrechts-Universität zu Knust. Max Planck Institute-CBG, Dresden, Saxony, Germany. Kiel, Institut für Humanernährung und Lebensmittelkunde, Molekulare Prävention, Kiel, Germany; 3) Institut für 184A Physiologische Chemie, Philipps Universität Marburg, Hessen, The Role of Cell Polarity in the Engulfment of Dying Germ Cells. Germany. Sarah E. Kleinsorge1, Sandy Serizier2, Tracy Meehan2, Jeffrey Taylor2, Kim McCall2. 1) GPGG, BUSM, Boston, MA; 2) Dept of 194B Biology, Boston University, Boston, MA. Exocyst complex are required for fusion of dense exocytotic rods to lacuna membrane in Drosophila nephrocytes to maintain highly 185B dynamic endocytic cycling. Fujian Zhang1, Ying Zhao1, Tiffany Characterization of novel interactors of the Drosophila Crumbs Chang1, Yufang Cao1, Katherine Muir1, Zhe Han1,2. 1) Dept. of complex. Ya-Huei Lin, Elisabeth Knust. MPI-CBG, Dresden, Internal Medicine, University of Michigan, Ann Arbor, MI; 2) Germany. Sanford Burnham Medical Research Institute, La Jolla, CA.

186C 195C The Drosophila planar polarity gene multiple wing hairs regulates Dynamin acts downstream of Tramtrack69 in the Drosophila ovary actin cytoskeleton. Qiuheng Lu, Dorothy Schafer, Paul Adler. to promote epithelial tube expansion. Nathaniel C. Peters, Celeste Biology Department, Department of Cell Biology and A. Berg. Department of Genome Sciences / Molecular and Cellular Morphogenesis and Regenerative Medicine Institute, University of Biology Program, University of Washington, Seattle, WA. Virginia, Charlottesville, Virginia, 22904. 196A 187A Endophilin B is required for the Drosophila oocyte to endocytose Apical Localization of the Integrin Heterodimer, αPS3βPS, yolk downstream of Oskar. Yi-Cheng Tsai1, Wei Chiang1, Willisa Promotes Engulfment and Cell Corpse Processing in the Liou4, Wei-Hao Lee1, Yu-Wei Chang1, Pei-Yu Wang2,3, Yi-Chen Drosophila Ovary. Tracy Meehan1, Allison Timmons1, Sarah Li1, Tsubasa Tanaka5, Akira Nakamura5, Li-Mei Pai1,2,3. 1) Kleinsorge2, Jeffrey Taylor1, Sarah Yunes1, Kimberly McCall1. 1) Graduate Institute of Biomedical Sciences, Chang Gung Department of Biology, Boston University, Boston, MA; 2) University, Tao-Yuan, Taiwan; 2) Department of Biochemistry, Graduate Program in Genetics and Genomics, Boston University, Chang Gung University, Tao-Yuan, Taiwan; 3) Chang Gung Boston, MA. Molecular Medicine Research Center, Chang Gung University, Tao-Yuan, Taiwan; 4) Department of Anatomy, College of 188B Medicine, Chang Gung University, Tao-Yua; 5) Department of Cell polarity and Notch signaling - an "EXTRA" job for Crumbs. Germline Development, Division of Organogenesis, Institute of Linda Nemetschke, Elisabeth Knust. Max Planck Institute of Molecular Embryology and Genetics, Kumamoto University 2-2-1 Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, Honjo, Kumamoto 860-0811 Japan. Dresden, Germany. 197B 189C Dop/MAST2 kinase promotes protrusion formation during the A Flamingo isoform lacking part of the Flamingo extracellular collective migration of border cells. George Aranjuez1,2, Alistair domain can send PCP signals in Fz -independent manner. Jun Wu, Langlands3, Arno Müller3, Jocelyn McDonald1,2. 1) Molecular Marek Mlodzik. Dept. of Developmental and Regenerative Genetics, Cleveland Clinic Foundation, Cleveland, OH; 2) Biology, Icahn Sch Medicine at Mount Sinai, New York, NY Genetics and Genome Sciences, Case Western Reserve University, 10029. Cleveland, OH; 3) Cell and Developmental Biology, University of Dundee, UK.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

198C 206B Mechanical feedback through E-cadherin amplifies guidance Functional analysis of Cell-ECM adhesion during Dorsal Closure signaling in collective border cell migration. Danfeng Cai1,2, using quantitative imaging and mathematical modeling. Katharine Mohit Prasad1,3, Shann-Ching Chen4, Li He1,5, Xiaobo Wang1,6, Goodwin, Stephanie Ellis, Emily Lostchuck, Qiming Wang, James Valerie Choesmel-Cadamuro6, Jessica Sawyer1,7, Gaudenz Feng, Guy Tanentzapf. University of British Columbia, Danuser8, Denise Montell1,2. 1) Department of Biological Vancouver, Canada. Chemistry, Johns Hopkins University, Baltimore, MD; 2) Molecular, Cellular and Developmental Biology Department 207C University of California, Santa Barbara, CA; 3) Department of Analysis of the role of talin in force-mediated regulation of Biological Sciences, IISER-Kolkata, West Bengal 741252, India; integrin turnover. Gudlaug K. Hakonardottir1, Raibatak Das3, 4) Life Technologies, South San Francisco, CA; 5) Department of Pablo Lopez1, Stefan Czerniecki1, Daniel Coombs2, Guy Genetics, Harvard Medical School, Boston, MA; 6) Université P. Tanentzapf1. 1) Department of Cellular and Physiological Sabatier Toulouse III, 31062 Toulouse cedex9. FRANCE; 7) Sciences, University of British Columbia, Life Science Institute, Department of Pharmacology and Cancer Biology, Duke 2350 Health Sciences Mall, Vancouver, British Columbia V6T University School of Medicine, Durham, NC; 8) Department of 1Z3, Canada; 2) Department of Mathematics and Institute of Cell Biology, Harvard Medical School, Boston, MA. Applied Mathematics, 1984 Mathematics Road, University of British Columbia, Vancouver, British Columbia V6T 1Z2, Canada; 199A 3) Integrative Biology, University of Colorado Denver, Denver, Epithelial rotation promotes the global alignment of contractile CO. actin filaments during Drosophila egg chamber elongation. Maureen P. Cetera1, Guillermina R. Ramirez-San Juan1, Patrick 208A W. Oakes1, Lindsay Lewellyn1,3, Michael J. Fairchild2, Guy The stability of the integrin adhesion complex is modulated by Tanentzapf2, Margaret L. Gardel1, Sally Horne-Badovinac1. 1) mechanical force. Pablo López Ceballos1, Guðlaug Katrín University of Chicago, Chicago, IL; 2) University of British Hákonardóttir1, Stefan Czerniecki1, Alejandra Herrera Reyes2, Columbia, Vancouver, BC, Canada; 3) Butler University, Raibatak Das3, Daniel Coombs2, Guy Tanentzapf1. 1) Cellular and Indianapolis, IN. Physiological Sciences, University of British Columbia, Vancouver, BC; 2) Mathematics, University of British Columbia, 200B Vancouver, BC; 3) Integrative Biology, University of Colorado Cytoskeletal and signaling factors act non-autonomously to Denver, Denver, CO. regulate dorsal appendage morphogenesis. Sandra G. Zimmerman, Celeste A. Berg. Deptartment of Gemone Sciences, 209B University of Washington, Seattle, WA. PDZ-GEF/Rap1 regulate dynamic cell adhesion during border cell collective migration. Ketki Sawant1,2, George Aranjuez1,3, Jocelyn 201C McDonald1,2,3. 1) Molecular Genetics, Lerner research institute, Regulation of Eyes shut trafficking and rhabdomere separation by cleveland, OH; 2) Cleveland State university, Cleveland , Ohio; 3) O-glucose. Amanda Haltom1,2, Tom Lee2, Beth Harvey3, Jessica Department of Genetics, School of Medicine, case Western Leonardi2,4, Yi-Jiun Chen5, Yang Hong5, Robert Haltiwanger3, Reserve University, OH. Hamed Jafar-Nejad1,2,4. 1) Program in Genes and Development, University of Texas Health Science Center, Houston, TX; 2) 210C Department of Molecular and Human Genetics, Baylor College of Automated multidimensional image analysis reveals a role for Abl Medicine, Houston, TX; 3) Department of Biochemistry and Cell in embryonic wound repair. Teresa Zulueta-Coarasa1, Rodrigo Biology, Stony Brook University, Stony Brook, NY; 4) Program in Fernandez-Gonzalez1,2,3. 1) Institute of Biomaterials and Developmental Biology, Baylor College of Medicine, Houston, Biomedical Engineering, University of Toronto, Toronto, ON; 2) TX; 5) Department of Cell Biology and Physiology, University of Department of Cell and Systems Biology, University of Toronto, Pittsburgh School of Medicine, Pittsburgh, PA. Toronto, ON; 3) Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON. 202A Actomyosin contraction assists lumen formation and expansion in 211A Drosophila photoreceptor cells. Jing Nie, Simpla Mahato, Andrew Quantification of mechanical force driving left-right asymmetric Zelhof. Department of Biology, Indiana University Bloomington, morphogenesis of the embryonic gut. Mai Adachi1, Naotaka Bloomington, IN. Nakazawa1,2, Reo Maeda2, Shukei Sugita3, Takeo Matsumoto3, Kenji Matsuno1. 1) Biological Sciences, Osaka University, 203B Toyonaka, Japan; 2) Biological Science & Technology, Tokyo Investigating the role of Mmp1 in cell migration using a larval University of Science, Katsushika, Japan; 3) Mechanical epidermis wound healing model. Erica Shannon, Joshua Clanton, Engineering, Nagoya Institute of Technology, Nagoya, Japan. Andrea Page-McCaw. Vanderbilt University Medical Center, Nashville, TN. 212B Huntingtin transports a novel class of vesicles on Drosophila larval 204C axons. Joseph White, Shruthi Srinivasan, Kan Hong Zheng, Differential Roles of Dock Family Members in Development. Shermali D. Gunawardena. Biological Sciences, SUNY at Bridget H. Biersmith1, Erika R. Geisbrecht1,2. 1) University of Buffalo, Buffalo, NY. Missouri - Kansas City, Kansas City, MO; 2) Kansas State Univerity, Manhattan, KS. 213C An analysis of maternally expressed Blastoderm specific gene 25D 205A in oogenesis and early Drosophila embryogenesis. Michelle A. Novel, tension-responsive adhesive structures mediate cell Kowanda1, Stephanie Yee1, Julie Bergalet2, Michal Wieczorek1, attachment to the ECM during dorsal closure. Stephanie J. Ellis, Gary Brouhard1, Eric Lécuyer2, Paul Lasko1. 1) McGill University, Katie Goodwin, Emily Lostchuck, Guy Tanentzapf. Cellular and Montreal, Quebec, Canada; 2) Institut de Recherches Cliniques de Physiological Sciences, University of British Columbia, Montréal, Montreal, Canada. Vancouver, BC, Canada.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

214A 223A Dynamic Actin-based Extensions Mediate Myoblast Fusion in Testing the models: Direct binding of β-catenin to the 20 amino Developing Flight Muscles. Dagan Segal, Benny Shilo, Eyal acid repeats of APC is dispensible for Wnt regulation. Robert Schejter. Department of Molecuar Genetics, Weizmann Institute of Yamulla, Eric Kane, Alexandra Moody, Kristin Politi, Andrew Science, Rehovot, Israel. Foley, David Roberts. Franklin & Marshall College, Lancaster, PA. 215B Fondue and Tiggrin Interaction at Muscle-Muscle Attachments. 224B Nicole Green1, Nadia Odell2, Clara Bazjek3, Shufei Zhuang4, A pilot screen for deficiencies that alter wing phenotypes from Mitch Dushay3, Erika Geisbrecht1. 1) Biochemistry & Molecular overexpression of a hyperactive Smad gene. Leeda Barikzi1,2, Biophysics Dept., Kansas State University, Manhattan, KS; 2) Cell Carla Cortez1,2, Lina Truong1,2, Laurel Raftery1. 1) School of Life Biology & Biophysics Dept., University of Missouri-Kansas City, Sciences, University of Nevada, Las Vegas, NV; 2) Authors Kansas City, MO; 3) Biology Dept., Illinois Institute of contributed equally to this work. Technology, Chicago, IL; 4) University of Kansas Cancer Center, Kansas University Medical Center, Kansas City, KS. 225C BMP signaling and extracellular matrix in the pupal wing are regulated by the receptor guanylyl cyclase Gyc76C and the cGMP-

dependent kinase Foraging. Justin Schleede, Seth S. Blair. Dept Cell Biology and Signal Transduction Zoology, Univ Wisconsin, Madison, WI.

226A 216C An Inwardly Rectifying K+ channel regulates Dpp Release. Giri Hyperphosphorylation and high levels of activity of the GPCR Raj Dahal, Emily Bates. Developmental Biology-PEDS, Univ Smoothened are regulated by the Fused kinase. Isabelle Becam1, Colorado Denver Anschutz Medical Campus, Aurora, CO. Matthieu Sanial1, Line Hofmann1, Julien Béhague1, Vanessa Gourhand1, Robert Holmgren2, Anne Plessis1. 1) Institut Jacques 227B Monod, CNRS, Univ Paris Diderot, F-75205 Paris, France; 2) Mad linker phosphorylation controls the range of BMP activity in Dept. of Mol. Biosc., Northwestern Univ., Evanston, IL 60208- the wing imaginal disc. Edward Eivers, Marlyn Rios, Matthew 3500, USA. Juarez, Fletcher Przybyla, Daniel Lee, Ashley Su, Abigail Aleman. Department of Biological Sciences, California State University Los 217A Angeles, Los Angeles, CA. 90032-8201. USA. Phosphorylation of the Smo tail is controlled by membrane localization and is dispensable for clustering. Adam P. Kupinski2, 228C Isabel Raabe1, Marcus Michel1, Christian Boekel1. 1) CRTD, TU A Novel Role for UDP-GlcNAc in Dpp Signal Antagonism. Dresden, Dresden, Germany; 2) Faculty of Biological Sciences, Matthew J. Moulton, Gregory B. Humphreys, Anthea Letsou. University of Leeds, Leeds LS2 9JT, UK. Human Genetics, University of Utah, Salt Lake City, UT.

218B 229A Characterization of a novel Wnt signaling factor regulating tissue Linker domain phosphorylation of Mad reduces its activity, homeostasis in the intestine of Drosophila melanogaster. Anna- independent of effects on protein levels. Seema Patel, Travis Lisa Boettcher, Teresa Eichenlaub, Jun Zhou, Michael Boutros. Parsons, Alexi Brooks, Laurel Raftery. School of Life Sciences, Division of Signaling and Functional Genomics, German Cancer University of Nevada, Las Vegas, Las Vegas, NV. Research Center, Heidelberg, Baden-Wurttemberg, Germany. 230B 219C Identification of novel maternal neurogenic genes that are potential Self-association of the APC tumor suppressor is required for the components of Notch signaling in Drosophila. Takuma Gushiken1,2, Kenjiroo Matsumoto2, Ryo Hatori2, Tomoko assembly, stability and activity of the Wnt signaling destruction 2 2 2 complex. Ezgi Kunttas-Tatli1, David Roberts2, Brooke M. Yamakawa , Takeshi Sasamura , Kenji Matsuno . 1) Department McCartney1. 1) Department of Biological Sciences, Carnegie of Biological Science and Technology, Tokyo University of Mellon University, Pittsburgh, PA 15213; 2) Department of Science, Japan; 2) Department of Biological Science, Osaka Biology, Franklin and Marshall College, Lancaster, PA 17604. university, Japan.

220A 231C Xylose is a novel ligand-specific regulator of Notch signaling in Genetic control of cardiac inflow tract formation. Dalea Nodal, 1 1,2 Gloriana Trujillo, Richard Cripps. Biology, Univ New Mexico, Drosophila. Tom Van Lee , Hamed Jafar-Nejad . 1) Department Albuquerque, NM. of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 2) Program in Developmental Biology, Baylor 221B College of Medicine, Houston, TX. An in vivo kinome and phosphatome RNAi screen in the Drosophila wing imaginal disc identifies a novel regulator of 232A Wnt/Wg secretion. Tirthadipa Pradhan, Esther Verheyen. Roles of glycan modifications of Notch receptor in Drosophila SSB7152,MBB, Simon Fraser Unversity, Burnaby, BC, Canada. Notch signaling. Kenjiroo Matsumoto, Akira Ishio, Takeshi Sasamura, Tomoko Yamakawa, Kenji Matsuno. Biological 222C Science, Osaka University, Toyonaka, Osaka, Japan. Drosophila Matrix Metalloproteinase 2 inhibits Wingless signaling and the proliferation of follicle stem cells via processing of Dally- 233B like protein. Xiaoxi Wang, Andrea Page-McCaw. Vanderbilt Drosophila TRAF2 physically interacts with Notch receptor and University Medical Center, Nashville, TN. downregulates its signaling activity. Abhinava K. Mishra, Nalani Sachan, Ashim Mukherjee. Molecular and Human Genetics, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Institute for Genomics and Systems Biology and Department of 234C Human Genetics, University of Chicago, Illinois, USA; 4) Animal Functions of a neurogenic gene, pecanex in Notch signaling. Genetics, Interfaculty Institute for Cell Biology, University of Tomoko Yamakawa, Yu Atsumi, Shiori Kubo, Kenji Matsuno. Tübingen, Germany; 5) Research Center for Environmental Osaka Univ, Osaka, Japan. Genomics, Organization of Advanced Science and Technology, Kobe University, Japan. 235A Ack regulates Dock localization to promote Drosophila 245B spermatogenesis. Abbas Abdallah, James Clemens, Henry Chang. Inhibition of JNK pathway by Myc under stress in Drosophila. Purdue University, West Lafayette, IN. Jiuhong Huang1,2, Li He2, Norbert Perrimon2, Lei Xue1. 1) School of Life Science and Technology, Tongji University, Shanghai, 236B China; 2) Department of Genetics, Harvard Medical School, Rap1 and PDZ-GEF contribute to the apical localization of the Boston, MA. Sevenless receptor tyrosine kinase during Drosophila eye development. Caroline Baril, Martin Lefrançois, Marc Therrien. 246C IRIC-University of Montreal, Montreal, PQ, Canada. Raw-Mediated JNK Signaling Antagonism: Keeping hyperactive JNK signaling in check. Molly C. Jud, Anthea Letsou. Human 237C Genetics, University of Utah, Salt Lake City, UT. Investigation of novel epidermal growth factor receptor target genes implicated in multiple aspects of Drosophila development. 247A Luke Dombert, Kristopher Krawchuk, Sean Thomas, Connor Rab GTPases and their role in glue secretion in the larval salivary Zale, Lisa Kadlec. Department of Biology, Wilkes University, gland. Kathryn Lantz, Christopher Hardy, Andrew Andres. Wilkes-Barre, PA. University of Nevada, Las Vegas, LAS VEGAS, NV.

238A 248B Screening for novel PLCγ inhibitors in Drosophila melanogaster. Dual functionality of O-GlcNAc transferase is required for Chitra Naidu, Claire Rosenwasser, Todd Rosenberg, Michelle Drosophila development. Daniel N. Mariyappa1, Xiaowei Latino, Justin Thackeray. Biology Department, Clark University, Zheng1, Arno Muller2, Daan van Aalten1,3. 1) MRC Protein Worcester, MA. Phosphorylation Unit, College of Life Sciences, University of Dundee, Dundee, Angus, United Kingdom; 2) Division of Cell and 239B Developmental Biology, College of Life Sciences, University of The dorsal ridge: a TGF-alpha-like mediated morphological Dundee, Dundee, Angus, United Kingdom; 3) Division of novelty on the Drosophila eggshell. Matthew G. Niepielko, Nir Molecular Microbiology, College of Life Sciences, University of Yakoby. CCIB, Rutgers University, Camden, NJ. Dundee, Dundee, Angus, United Kingdom.

240C 249C PVR receptor tyrosine kinase is required for dorsal closure in Hemocyte-mediated repair: promoting retinal repair with MANF. parallel with JNK signaling. Rebecca Garlena1, Ashley Lennox2, Joana Neves, Deepak Lamba, Heinrich Jasper. Buck Institute for Beth Stronach1. 1) Dept Micro & Mol Genetics, Univ Pittsburgh Research on Aging, Novato, CA. Sch Medicine, Pittsburgh, PA; 2) Dept Mol Genetics & Micro, Duke Univ Med Cntr, Durham, NC. 250A PS2 Integrins are important for glia cell migration into the eye 241A imaginal disc. Ligia Tavares, Emiliana Pereira, Rui Traquete, Src-kinases and ERK activate distinct responses to Stitcher Andreia Correia, Nuno Amaral, João B. Relvas, Paulo S. Pereira. receptor tyrosine kinase signaling during wound healing in IBMC, Porto, Porto, Portugal. Drosophila. Vasilios Tsarouhas, Liqun Yao, Christos Samakovlis. Molecular Biosciences, The Wenner-Gren Institute, Stockholm 251B University, Stockholm, Sweden. A novel tool to monitor and specifically manipulate cells in which Yorkie is nuclear. Ryohei Yagi, Marc Debrunner, Franz Mayer, 242B Konrad Basler. Institute of Molecular Life Sciences, University of An in vivo RNAi screen identifies new regulators of invasive cell Zürich, Zürich, Switzerland. specification. Afsoon Saadin, Michelle Starz-Gaiano. University of Maryland Baltimore County, Baltimore, MD. 252C Characterization of the subcellular localization of BMP receptors. 243C Ilaria Alborelli, Markus Affolter. Biozentrum, Basel, Switzerland. Localization of Insulin Receptor Function in Metabolic Regulation of Sleep. Wesley L. Bollinger1, Katelyn Offerdahl1, Pavel Masek1, 253A Yoon-Joon Kim2, Alex Keene1. 1) Biology, University of Nevada, JNK and DPP act in a feed-forward loop to achieve robustness Reno, Reno, NV; 2) Life Science, Gwangju University, Gwangju, during Dorsal Closure. Antoine Ducuing, Bertrand Mollereau, South Korea. Stephane Vincent. LBMC, Ecole Normale Supérieure de Lyon, Lyon, France. 244A Pri peptides mediate ecdysone developmental timing for epidermal 254B morphogenesis. Helene Chanut-Delalande1,2, Yoshiko The Polarized Deposition of Basement Membrane Proteins Hashimoto5, Anne Pélissier-Monier1,2, Rebecca Spokony3, Azza Depends on Phosphatidylinositol Synthase and the Levels of Dib1,2, Jérôme Bohère1,2, Yvan Latapie1,2, Philippe Valenti1,2, Phosphatidylinositol 4,5-bisphosphate. Olivier Devergne, Karen Cédric Polesello1,2, Bernard Moussian4, Kevin White3, Serge Tsung, Gail Barcelo, Trudi Schüpbach. HHMI/Molecular Biology, Plaza1,2, Yugi Kageyama5, François Payre1,2. 1) Centre de Biologie Princeton University, Princeton, NJ. du Développement, Toulouse, France; 2) CNRS, UMR5547, Centre de Biologie du Développement, Toulouse, France; 3)

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

255C 264C An examination of the requirement for septate junction Evaluating the requirement of Mcm10’s expanded CTD in D. components during morphogenesis in Drosophila melanogaster. melanogaster. Michael C. Reubens, Tim W. Christensen. Sonia Hall, Beth Jarvis, Robert Ward. Molecular Biosciences, Biology, East Carolina University, Greenville, NC. University of Kansas, Lawrence, KS. 265A 256A Investigating the Interaction of RecQL4 and Mcm10 in Drosophila The Drosophila T-box Transcription Factor Midline Functions melanogaster. Wayne Rummings, Michael Reubens, Lucas within the Insulin Receptor Activated Signaling Pathway to Hopkins, Tim Christensen. Biology, East Carolina University, Regulate Interommatidial Bristle Formation and Cell Survival. Greenville, NC. Sandra M. Leal, Qichuan Chen, Sudeshna Das, Yan Zong, Robert Smith, Kelly Odom, Wisam Buti, Brielle Menegazzi. Dept 266B Biological Sci, Univ Southern Mississippi, Hattiesburg, MS. Essential role of the BLM helicase in syncytial cycles. Eric P. Stoffregen1, Kathryn P. Kohl1,2, Susan McMahon1, Jeff 257B Sekelsky1,2. 1) Department of Biology, University of North Functional specificity in highly conserved Drosophila zinc Carolina, Chapel Hill, NC 27599; 2) Curriculum in Genetics and transport genes. Christopher D. Richards, Jessica Lye, Richard Molecular Biology. Burke. School of Biological Science, Monash University, Melbourne, Australia. 267C Intrinsic and extrinsic signals activate neural stem cell apoptosis 258C through coordinated cell death gene expression. Richa Arya, Digitor, an Essential Protein with Homology to Mammalian Tatevik Keshishyan, Kristin White. CBRC, MGH/HARVARD, ATMIN is Involved in Brain Development and Oxidative Stress CHARLESTOWN, MA. Pathways in Drosophila. Saheli Sengupta, Changfu Yao, Uttama Rath, Jack Girton, Jorgen Johansen, Kristen Johansen. 268A Biochemistry, Biophysics & Molecular Biology, Iowa State The role of pro-apoptotic genes in the developing Drosophila optic University, Ames, IA. lobe cell death. Hidenobu Tsujimura1, Ayaka Tsutsumi1, Kengo Beppu1, Yu Togane1, Yusuke Hara1, Hiromi Akagawa1,2, Ryo 259A Iiduka1. 1) Dept Dev Biol, Tokyo Univ Agric & Tech, Fuchu-si, Drosophila Acinus: A Genetic Link Between Autophagy and Tokyo, Japan; 2) Department of Biological Production Science, Hippo Signaling. Lauren K. Tyra1, Nilay Nandi1, Gabrielle Tokyo University of Agriculture and Technology. Zuniga2, Cecilia Esquivel3, Helmut Krämer1. 1) Neuroscience, UT Southwestern Medical Center, Dallas, TX; 2) SURF Program, UT 269B Southwestern Medical Center, Dallas, TX; 3) STARS Program, Drosophila MOF and genome stability: a chromatin modifier to the UT Southwestern Medical Center, Dallas, TX. rescue. Arpita Sarkar1, Sncvl Pushpavalli1, Manika Pal-Bhadra1, Utpal Bhadra2. 1) chemical biology, IICT, Hyderabad, Andhra Pradesh, India; 2) Centre for Cellular and Molecular

Biology,Hyderabad. Cell Cycle and Cell Death 270C NuA4 Acts as a Timer in the Transition to a Postmitotic State. 260B Kerry Flegel, Olga Grushko, Kelsey Bolin, Ellen Griggs, Laura Mitotic role of SCFSkp2 in maintaining genome stability. Biju Buttitta. University of Michigan, Ann Arbor, MI. Vasavan, Nilanjana Das, Andrew Swan. Biological Sciences, University of Windsor, Windsor, Ontario, Canada. 271A Regulation of cell death in the Drosophila ovary by Snail family 261C genes. Victoria Kathryn Jenkins, Kim McCall. Department of The roles of mir-2a in Drosophila eye development. Su-Wen Biology, Boston University, Boston, MA. Cheng2,3, Y. Henry Sun2,3, Yu-Chen Tsai1. 1) Dept Life Science, Tung-hai Univ, Taichung, Taiwan; 2) Institute of Genetics, Yang- 272B Ming Unv, Taipei, Taiwan; 3) Institute of Mol., Bio., Academia Salvador-Warts-Hippo pathway in a developmental checkpoint monitoring Helix-Loop-Helix regulation. Lan-Hsin Wang1, Sinica, Taipei, Taiwan. 1,2,3 Nicholas Baker . 1) Genetics Dept, Albert Einstein College of 262A Medicine, NY; 2) Developmental and Molecular Biology Dept, Evaluating the Roles of Blm and rtel in Homologous Albert Einstein College of Medicine; 3) Ophthalmology and Visual Recombination in D. melanogaster. Christopher Rota, Susan Sciences Dept, Albert Einstein College of Medicine. McMahan, Jeff Sekelsky. Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC. 273C The Drosophila effector caspase Dcp-1 regulates mitochondrial 1,2 263B dynamics and autophagic flux via SesB. Sharon M. Gorski , Lindsay DeVorkin1,2, Nancy Erro Go1,2, Claire Hou1,2, Annie Mutations in C-terminal domain of Orc6 affect origin recognition 1 1,2 complex function. Maxim Balasov1, Franziska Bleichert2, Michael Moradian , Gregg B. Morin . 1) Genome Sciences Centre, British Botchan3, James Berger3, Igor Chesnokov1. 1) Department of Columbia Cancer Agency, Vancouver, BC, Canada; 2) Molecular Biochemistry and Molecular Genetics, University of Alabama at Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Birmingham School of Medicine; 2) Miller Institute for Basic Canada. Research in Science, University of California, Berkeley; 3) Department of Molecular and Cell Biology, University of California, Berkeley.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

274A 284B A novel Fizzy/Cdc20-dependent mechanism suppresses necrosis in Synaptonemal Complex Protein c3G is required for regulating neural stem cells. Chaoyuan Kuang1, Krista Golden2, John crossover frequency. John R. Merriam. Dept Molec/Cell/Dev Damrath2, Claudio Simon2, Laura Buttitta5, Cheng-Yu Lee1,2,3,4. 1) Biol, Univ California, Los Angeles, CA. Program in Cellular and Molecular Biology; 2) Life Sciences Institute; 3) Department of Internal Medicine; 4) Department of 285C Cell and Developmental Biology, University of Michigan Medical Effects of SMC3 RNAi knockdown in Drosophila male meiosis. School; 5) Department of Molecular, Cellular and Developmental Avik Mukherjee. Genome Science and Technology, University of Biology, University of Michigan, Ann Arbor. Tennessee, Knoxville, TN.

275B 286A Quantitative Analysis of Drosophila Embryonic Epidermal A splice variant of centrosomin (Cnn) converts mitochondria into Development. Cody E. Narciso1, Jessica Freeman1, Jochen MTOCs to facilitate sperm tail elongation. Jieyan Chen, Timothy Kurswe2, Alexander Fletcher2, Jeremiah Zartman1. 1) University of Megraw. Biomedical Sciences, Florida State University, Notre Dame, IN; 2) Wolfson Centre for Mathematical Biology, Tallahassee, FL. Mathematical Institute, University of Oxford, Oxford, U K. 287B 276C The PCL acts as a sperm centriolar precursor during fertilization. Dmp53 interacts with the Hippo pathway to regulate cell Atul Khire1, Stephanie Blachon2, Tomer Avidor-Reiss1. 1) proliferation and apoptosis. Shilpi Verghese1, Amit Singh1,2,3, Department Biological Sciences, The University of Toledo, Madhuri Kango-Singh1,2,3. 1) Department of Biology, University of Toledo, OH-43606; 2) Hybrigenics, 3-5 impasse Reille, 75014 Dayton, OH; 2) Center for Tissue Regeneration and Engineering at PARIS. Dayton (TREND); 3) Premedical Programs, Univ of Dayton, OH . 288C 277A Isoform-specific functions of Mud/NuMA mediate binucleation of Cell death as a defence against cytosolic DNA in Drosophila. Drosophila male accessory gland cells. Kiichiro Taniguchi1, Nazarii Vitak1, Karyn Johnson2, David Sester1, Katryn Stacey1. 1) Akihiko Kokuryo2,3, Takao Imano2,3, Ryunosuke Minami4, Hideki School of Chemistry and Molecular Biosciences, University of Nakagoshi4, Takashi Adachi-Yamada1,2,3. 1) Dept. Life Sci., Fac. Queensland, Brisbane, QLD, Australia; 2) School of Biological Sci., Gakushuin University, Tokyo, Japan; 2) Inst. Biomol. Sci., Sciences, University of Queensland, Brisbane, QLD, Australia. Gakushuin University, Tokyo, Japan; 3) Dept. Biol., Grad. Sch. Sci., Kobe University, Kobe, Japan; 4) Grad. Sch. Nat. Sci./Tech., Okayama University, Okayama, Japan.

Cell Division and Growth Control 289A Small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines. Miranda 1 1 2 1 278B Burnette , Jonathan Chen , Jun Li , Jeremiah Zartman . 1) Examination of the ER-specific Rab10 GTPase on ER partitioning Department of Chemical and Biomolecular Engineering, during mitosis. Elliott Holt, Zane Bergman, Blake Riggs. Biology, University of Notre Dame, Notre Dame, IN; 2) Department of San Francisco State University, San Francisco, CA. Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame IN. 279C Spindle Matrix Formation is Required for Cyclin B Localization, 290B Nuclear Envelope Breakdown, and Cell Cycle Progression. Jorgen Troponin-I localizes cell polarity signals and is required for tumor Johansen, Changfu Yao, Jack Girton, Kristen Johansen. Biochem, growth. Sergio Casas-Tinto, Alberto Ferrus. Cajal Institute, Biophys & Molec Biol, Iowa State Univ, Ames, IA. Madrid, Spain.

280A 291C Drosophila cytokinesis proteins regulate meiotic spindle assembly A screen for Tribbles interacting genes using FijiWings, a toolkit and homologue bi-orientation in oocytes. Arunika Das, Kim for semi-automated wing morphometric analysis. Leonard L. McKim. Waksman Institute,Rutgers University, New Jersey. Dobens, Anna Shipman. Sch Biological Sci, Univ Missouri, Kansas City, Kansas City, MO. 281B Proposed cohesin complexes in Drosophila meiosis. Mercedes R. 292A Healing a fly by increasing cell size through polyploidization and Gyuricza, Kathryn B. Landy, Kim S. McKim. Waksman Institute, 1 1,2 Rutgers University, Piscataway, NJ. fusion. Vicki Losick , Allan Spradling . 1) Dept Embryology, Carnegie Institution for Science, Baltimore, MD; 2) Howard 282C Hughes Medical Institute. Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development. Eric Joyce, C.- 293B ting (Ting) Wu. Department of Genetics, Harvard Medical School, CG10126 is a downstream target of EGFR signaling. Qian Nie, Boston, MA. Susan Spencer. Department of Biology, Saint Louis, MO.

283A 294C Non-autonomous tissue growth by endocytic regulation of Eiger Analysis of Meiotic functions of Sisters Unbound Reveals 1,2 1 1 and Ras signaling. Kyoko Takino , Shizue Ohsawa , Tatsushi Similarities to Drosophila Cohesion Proteins. Badri Krishnan , 1,3 Sharon Thomas1, Igor Zhulin2, Hirotsugu Yamada1, Rihui Yan1, Igaki . 1) Lab. of Genetics, Kyoto Univ. Grad. Sch. of Biostu, Bruce McKee1. 1) BCMB , University of Tennessee Knoxville, Kyoto, Kyoto, Japan; 2) Division of Genetics, Kobe Univ. Grad. Knoxville, TN; 2) Department of Microbiology, University of Sch. of Med; 3) PRESTO, Japan Science and Technology Agency. Tennessee, Knoxville.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

295A 306C Identification and study of new genes involved in epithelial growth Mosaic Ribosomal protein S6 deficiency: a Minute mouse model and morphogenesis. Parvathy Venugopal, Vincent Mirouse. for studying cell competition. Laina Freyer, Nicholas E. Baker, GReD, Clermont University, CNRS UMR 6293, INSERM U1103, Bernice E. Morrow. Genetics, Albert Einstein College of Clermont-Ferrand, France. Medicine, Bronx, NY.

296B 307A Regulation of Hippo signaling by EGFR-MAPK signaling through A Transcriptional profiling approach to identify genes defining the Ajuba family proteins. Venu Reddy Bommireddy Venkata1,2, loser cell identity in cell competition. Iwo Kucinski, Eugenia Ken Irvine2. 1) KS 338D, ACTREC, TMH, Navi Mumbai, Piddini. Gurdon Inst, University of Cambridge, Cambridge, U K. Maharastra, India; 2) Waksman Institute, Rutgers University, Piscatway, NJ 08854. 308B Mechanical processing of differential cell division during epithelial 297C cell competition. Alice Tsuboi1, Shizue Ohsawa2, Kenji Matsuno1, Nitric oxide signaling in the prothoracic gland regulates growth Tatsushi Igaki2, Koichi Fujimoto1. 1) Graduate School Of Science, coordination during the regeneration checkpoint. Jacob Jaszczak, Osaka Univ., toyonaka, Japan; 2) Graduate School Of Biostudies, Jacob Wolpe, Anh Dao, Adrian Halme. Department of Cell Kyoto Univ., Sakyo-ku, Japan. Biology, University of Virginia School of Medicine, Charlottesville, VA. 309C A Drosophila model to study signaling and intercellular 298A interactions that Promote Aggressive Tumorigenesis. Indrayani Genetic control of tissue specific growth in the larval trachea of Waghmare1, Shilpi Verghese1, Austin Roebke3, Amit Singh1,2,3, Drosophila. Paulo Leal, Brett Bohmann, Cyril Cook, Alex Madhuri Kango-Singh1,2,3. 1) Univ of Dayton, OH; 2) Center for Matlock, Robert Ward. Dept. of Molecular Biosciences, University Tissue Regeneration and Engineering at Dayton (TREND), Univ of Kansas Lawrence, KS. of Dayton, OH; 3) Premedical Programs, Univ of Dayton, OH.

299B 310A Non-cell autonomous tumor progression driven by cell cycle Identification of factors regulating regenerative growth in arrest. Nakamura Mai1, Ohsawa Shizue1, Igaki Tatsushi1,2. 1) Drosophila imaginal discs. Syeda Nayab Fatima Abidi, Amanda Kyoto University, Kyoto, Sakyo-ku, Japan; 2) PRESTO, JST, Brock, Sumbul Jawed Khan, Rachel Smith-Bolton. CDB, UIUC, Japan. Urbana, IL.

300C 311B Identification of new Fat-Dachsous signaling regulators in growth Pattern reorganization occurs independently of cell division during control. Yifei Zhang, Xing Wang, Seth Blair. Zoology Dept, UW Drosophila wing disc regeneration in situ. Sandra Diaz-Garcia1, Madison, Madison, WI. Antonio Baonza2. 1) Division of Biological Sciences, Univ of California, San Diego; 2) Centro de Biología Molecular Severo 301A Ochoa, Universidad Autonoma de Madrid. Madrid, Spain. Dynein Light Chain 1 (DLC1) is required for normal growth in Drosophila Melanogaster. Daniel Allyn Barron, Kenneth Moberg. 312C Dept Cell Biol, Emory Univ Sch Med, Atlanta, GA. Control of cell division during epithelial repair. Telmo Pereira, Marco Antunes, Antonio Jacinto. CEDOC - Centre for Studies in 302B Chronic Diseases, Lisboa, Portugal. Regenerative signals regulate the timing of epithelial tumor development through ecdysone signaling. Thu Tran, Rebecca 313A Garrett, Rajan Bhandari, Adrian Halme. Cell Biology, University Nucleoporin Nup98 is required for normal tissue growth and cell of Virginia, Charlottesville, VA. cycle regulation. Kiriaki Kanakousaki, Olga Grushko, Laura Buttitta. Molecular, Cellular and Developmental Biology, 303C University of Michigan, Ann Arbor, MI. Disc overgrown (Dco) as a player in Drosophila haematopoiesis. Lucie Jonatova, Tomas Dolezal. University of South Bohemia, 314B Ceske Budejovice, Czech Republic. Uncovering the principles of organ regeneration in Drosophila using whole-genome transcription profiling. Sumbul Jawed 304A Khan, Syeda Nayab Fatima Abidi, Yuan Tian, Rachel K. Smith- d-Csk regulates growth via the Hippo signaling pathway. Hailey J. Bolton. Cell and Developmental Biology, University of Illinois at Kwon1, Indrayani Waghmare1, Shilpi Verghese1, Madhuri Kango- Urbana Champaign, Urbana, IL. Singh1,2,3. 1) Department of Biology, University of Dayton, Dayton, OH; 2) Center for Tissue Regeneration and Engineering at 315C Dayton, Dayton, OH; 3) Premedical Programs, University of Chameleon: a mutant with an increased frequency of notum-to- Dayton, Dayton, OH 45469. wing transdetermination. Melanie I. Worley, Iswar K. Hariharan. Molec & Cell Biol, Univ California, Berkeley, Berkeley, CA. 305B A role for Spaetzle in sensing and signaling during cell 316A competition. Lale Alpar1, Cora Bergantiños2, Marc Amoyel2, Zonda: a novel gene involved in autophagy and growth control. Laura A. Johnston2. 1) Biological Sciences, Columbia University, Mariana Melani1, Nuria Romero1, Julieta Acevedo1, Joel Perez New York, NY; 2) Genetics and Development, Columbia Perri1, Eleonora Sorianello1, Ayelen Valko1, Milton Aguilera2, University, New York, NY. Maria Colombo2, Pablo Wappner1. 1) Fundacion Instituto Leloir- CONICET, Buenos Aires, Argentina; 2) Instituto de Histología y Embriología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo-CONICET, Mendoza, Argentina.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

317B 327C Muscle organizer cells regulate myoblast proliferation during adult Seipin promotes adipose tissue fat storage through the ER Ca2+- myogenesis in Drosophila. Kumar Vishal, Mary Turvy, Kevin ATPase SERCA. Junfeng Bi, Wei Wang, Zhonghua Liu, Xun Venczel, Lindsay Grainger, Joyce Fernandes. Department of Huang. Institute of Genetics and Developmental Biology, CAS, Zoology, Maimi University, Oxford, OH. Beijing, China.

328A The Roles of Endocannabinoids and Their Chemical Relatives in Physiology, Organismal Growth, and Regulating Drosophila melanogaster Metabolism. Ruth A. Bishop. Biology, The University of Alabama, Shreveport, LA. Aging 329B Metabolism and Locomotion in Anoxic Drosophila. Viviane 1 2 1 1 318C Callier , Steven C. Hand , Jacob B. Campbell , Jon F. Harrison . Mating-Reward Reverses the Effects of Pheromone Perception in 1) Arizona State University, Tempe, AZ; 2) Louisiana State Drosophila. Zachary M. Harvanek1,2, Christi M. Gendron1, Brian University, Baton Rouge, LA. Y. Chung1, Scott D. Pletcher1. 1) Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI; 2) Medical 330C Dietary and Genetic Regulation of Longevity and Neuronal Scientist Training Program, University of Michigan, Ann Arbor. 1,2,3 1 Function in Drosophila. Eric Ratliff , Madhulika Achal , Roxanne Kotzebue1,2, Arysa Gonzalez1,2,3, Ruth Mauntz1,3, Kim 319A 1,3 Drosophila embryogenesis scales uniformly across temperature in Finley . 1) Shiley BioScience Center, San Diego State University, diverse species. Steven G. Kuntz1,2, Michael B. Eisen1,2,3. 1) QB3, San Diego, CA; 2) Dept. Biology, SDSU; 3) Expression Drug UC Berkeley, CA; 2) Dept of Molecular and Cell Biology, UC Designs, LLC., SDSU, San Diego, CA. Berkeley, CA; 3) Howard Hughes Medical Institute, UC Berkeley. 331A 320B Genetic and metabolic bases of thermal plasticity in Drosophila. Role of ADI1 in regulation of ER stress. Wei-Cheng Lin, Li-Mei Luke A. Hoekstra, Kristi L. Montooth. Dept Biol, Indiana Univ, Pai. Chang-Gung University, Tao-Yuan, Taiwan. Bloomington, IN.

321C 332B Heat stress disrupts key events in early embryonic development. Lost in translation: a mitonuclear interaction affecting metabolism, stress resistance and aging associated with mitochondrial tRNA Brent L. Lockwood, Kristi L. Montooth. Biology, Indiana 1 2 University, Bloomington, IN. mutations. Marissa A. Holmbeck , David M. Rand . 1) Bio-Med, Brown University, Providence, RI; 2) Ecology and Evolutionary 322A Biology, Brown University, Providence RI, USA. Oxidative stress and the fly metabolome. Thomas JS Merritt, Jose M. Knee. Chemistry & Biochemistry, Laurentian University, 333C Sudbury, Ontario, Canada. Regulation of energy metabolism by the nuclear receptor DHR78. Stefanie M. Marxreiter, Carl S. Thummel. Human Genetics, 323B University of Utah, Salt Lake City, UT. The Fruit Fly: A Tractable System to Study Cold Tolerance. Daniel Ricketti1, David Luor1, Kosha Parikh1, Nuray Sariaydin1, 334A Mohammad Khan1, Alessio Russomanno1, Daniel Shain1,2, Nir Regulation of glucose homeostasis by dsir2 in Drosophila Yakoby1,2. 1) Biology Dept, Rutgers, The State University of New melanogaster. Rebecca A. Somer, Carl S. Thummel. Human Jersey, Camden; 2) Center for Computational and Integrative Genetics, University of Utah, Salt Lake City, UT. Biology, Rutgers, The State University of New Jersey, Camden. 335B 324C Rapamycin increases mitochondrial efficiency by mtDNA- dependent reprogramming of mitochondrial metabolism in A Role for Drosophila p38 MAP Kinase in Protein Homeostasis. 1 2 1 2 3 Drosophila. Eugenia Villa-Cuesta , Marissa Holmbeck , David Sarah Ryan , Amelia M. Burch , Subhabrata Sanyal , Alysia D. 2 Vrailas-Mortimer1. 1) Biological Sciences, University of Denver, Rand . 1) BIOLOGY, DEPARTMENT OF, Adelphi University, Denver, CO; 2) Department of Cell Biology, Emory University, Garden City, NY; 2) Department of Ecology and Evolutionary Atlanta, GA; 3) BiogenIdec, Boston, MA. Biology, Brown University, RI, USA.

325A 336C Hypoxia-induced insulin resistance and associated lipid Comparing Nutrient Restrictions and its Effects on Metabolic Output in Drosophila melanogaster. Rebecca A. Vaders1, Alexis metabolism defects in Drosophila melanogaster. Daniel Wong, 1,2 Julian Martinez-Agosto. Department of Human Genetics, A. Nagengast . 1) Chemistry, Widener University, Chester, PA; University of California, Los Angeles, Los Angeles, CA. 2) Biochemistry, Widener University, Chester, PA.

326B 337A Desiccation regulates innate immunity via ecdysone signaling in Mio and bigmax act in the brain to control feeding and metabolism Drosophila Malpighian tubules. Wenjing Zheng1, Ana in Drosophila. James E. Docherty, Sarah M. Rosenheck, Joseph Hernandez1, Florintina Rus2, Neal Silverman2, Marc Tatar1. 1) E. Manno, Jacqueline E. McDermott, Justin R. DiAngelo. Biology, Ecology and Evolutionary Biology Department, Brown University, Hofstra University, Hempstead, NY. Providence, RI, USA; 2) Division of Infectious Diseases, Department of Medicine, Univ of Massachusetts Medical, Worcester, MA,.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

338B 346A The Role of dTORC1 on Muscle Development, Function and Met/Gce is a bona fide juvenile hormone receptor. Marek Longevity in Drosophila. Isabelle Hatfield1, Erika Yates1, Jindra1,2, Jean-Philippe Charles3, Vlastimil Smykal1, Mirka Lawrence Reiter2,3, Dave Bridges1,3. 1) Department of Physiology, Uhlirova4, Ron Hill2. 1) Dept Gen, Biol Ctr ASCR, Ceske University of Tennessee Health Science Center, Memphis, TN; 2) Budejovice, Czech Republic; 2) Animal, Food and Health Department of Neurology, University of Tennessee Health Science Sciences, CSIRO, North Ryde NSW, Australia; 3) Université de Center, 855 Monroe Avenue, Memphis, Tennessee 38163; 3) Bourgogne, Dijon, France; 4) Institute for Genetics, CECAD Children's Foundation Research Institute, Le Bonheur Children's Cologne, University of Cologne, Cologne, Germany. Hospital, Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Memphis, TN 38103. 347B Drosophila neurotrophin Spätzle5 is required for ecdysone 339C synthesis. Qiuxiang Ou, Brian Phelps, Kirst King-Jones. The Effect of Bacteria on Oviposition Preference of Drosophila Biological Sciences, University of Alberta, Edmonton, Alberta, melanogaster. Geon Ho Kim, Peter Newell, Angela Douglas. Canada. Entomology, Cornell University, Ithaca, NY. 348C 340A The effects of Bisphenol A (BPA) and Bisphenol S (BPS) on The Modified Effects of Bisphenol A (BPA) in Response to growth and development in Drosophila: A comparative study. Dietary Composition. Ashley L. Parker, Trisha M. Zintel, Amber Amber K. Weiner, Trisha M. Zintel, Ashley L. Parker, K. Weiner, AnnJosette Ramirez, Sheryl T. Smith. Biology, Arcadia AnnJosette Ramirez, Sheryl T. Smith. Biology, Arcadia University, Glenside, PA. University, Glenside, PA.

341B 349A Identification of Neurosensory Mechanism for Dietary Protein by Nocturnin (curled) is involved in the regulation of ecdysone Drosophila melanogaster. Jennifer Ro1, Gloria Pak2, Scott D. production via interaction with Drosophila Hormone Receptor 4. Pletcher3. 1) Cellular and Molecular Biology, University of Jie Zeng, Qiuxiang Ou, Kirst King-Jones. Biological Sciences, Michigan, Ann Arbor, MI; 2) College of Literature, Science and University of Alberta, Edmonton, Alberta, Canada. the Arts, University of Michigan, Ann Arbor, MI; 3) Molecular and Integrative Physiology, University of Michigan, Ann Arbor, 350B MI. Exposure of D. melanogaster larvae to BDE-47 is associated with altered larval growth and delayed pupal development. Trisha M. 342C Zintel, Ashley L. Parker, Amber K. Weiner, AnnJosette Ramirez, Rapamycin reduces Drosophila longevity under low nutrition. Shane A. Harris, Sheryl T. Smith. Biology Dept, Arcadia Eugenia Villa-Cuesta1, Rand David2. 1) BIOLOGY, University, Glenside, PA. DEPARTMENT OF, Adelphi University, Garden City, NY; 2) Department of Ecology and Evolutionary Biology, Brown 351C University, Providence, RI , USA. Does Rapamycin improve lifespan and healthspan? A test with multiple mitonuclear genotpyes and dietary treatments. James A. 343A Mossman, Julia Donner, Denise Croote, Russyan Mark Mabeza, Influence of gene duplication on a critical hormone signaling Matthew Min, Michele Koh, Neha Mehta, Emma Blake, Eugenia pathway in Drosophila. Aaron Baumann, Raechel Warner, Villa Cuesta, David Rand. Ecology and Evolutionary Biology, Michael Texada, Hui-Min Chen, James Truman, Lynn Riddiford. Brown University, Providence, RI. Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA. 352A The Role of miR-310s in ovarian soma in response to dietary 344B conditions. Omer Cicek, Halyna Shcherbata. MPRG of Gene The Drosophila Neuropeptide F Circuit Integrates Sleep and Expression and Signaling, Max Planck Institute, Goettingen, Feeding Behavior to Regulate Aging. Brian Y. Chung1, Jenny Germany. Ro2, Kylie Miller3, Scott D. Pletcher1. 1) Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, 353B MI; 2) Cellular and Molecular Biology Graduate Program, A proteomic screen towards identifying fat body factors University of Michigan Medical School, Ann Arbor, MI; 3) transmitting nutritional status to stem cell lineages in the College of Literature, Science, and the Arts, University of Drosophila ovary. Shinya Matsuoka1,3, Alissa Armstrong1,3, Michigan, Ann Arbor, MI. Leesa Sampson1, Kaitlin Laws1, Robert Cole2, Daniela Drummond-Barbosa1. 1) Biochemistry and Molecular Biology, 345C JHU Bloomberg School of Public Health, Baltimore, MD; 2) Mass The steroid deficiency protein Ecdysoneless is a pre-mRNA Spectrometry and Proteomics Facility, JHU School of Medicine, splicing factor. Ann-Katrin Claudius1, Patrizia Romani2, Tobias Baltimore, MD; 3) These authors contributed equally. Lamkemeyer3, Marek Jindra4, Mirka Uhlirova1. 1) Institute for Genetics, CECAD Cologne, University of Cologne, Cologne, 354C Germany; 2) Dipartimento di Biologia Evoluzionistica The regulation of muscle function by Mio in Drosophila. Sperimentale, Università di Bologna, Bologna, Italy; 3) Proteomics Grzegorz Polak, Justin R. DiAngelo. Department of Biology, Facility, CECAD, University of Cologne, Cologne, Germany; 4) Hofstra Univ, Hempstead, NY. Biology Center, Academy of Sciences of the Czech Republic, Ceske Budejovice, Czech Republic. 355A Analysis of βν integrin mutant showing a premature aging phenotype in Drosophila adult midgut. Takashi Okumura1,2, Koji Takeda1, Kiichiro Taniguchi1, Takashi Adachi-Yamada1. 1) Dept of Life Science, Gakushuin University; 2) Department of Physics, Faculty of Science and Engineering, Waseda University.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

367A 356B A DGRP screen to identify host response factors to growth Salivary gland subcellular organization and regulatory promotion effect mediated by Lactobacillus plantarum. Dali Ma, conservation in Anopheles mosquitoes. Michael B. Wells, Claire-Emmanuelle Indelicato, François Leulier. Institut de Deborah J. Andrew. Cell Biology, Johns Hopkins University Genomique Fonctionnelle de Lyon, ENS de Lyon, Lyon, France. School of Medicine, Baltimore, MD. 368B 357C Characterization of Bacterial factors underlying Drosophila - Insulin signaling related function of Tribbles during Drosophila Lactobacilli mutualistic interactions. Gilles Storelli1, Jumamurat development. Rahul Das, Zach Sebo, Leonard Dobens. Cell & Bayjan2, Roland Siezen2, Sacha Van Hijum2, François Leulier1. 1) Molecular Biology, University of Missouri-Kansas City, Kansas Institute of Functional Genomics Lyon (IGFL), CNRS UMR5242, City, MO 64110. Ecole Normale Supérieure de Lyon, Lyon, France; 2) Nijmegen Centre for Molecular Life Sciences, CMBI, Nijmegen, The 358A Netherlands. Effect of insulin signaling on sexual attractiveness and performance. Tatyana Y. Fedina, Scott D. Pletcher. Molecular & 369C Integrative Physiology, University of Michigan, Ann Arbor, MI. Transcription factors FTZ-F1 and Blimp-1 in fat body control the pupal development and eclosion timing in Drosophila. Hitoshi 359B Ueda1,2, Abdel-Rahman Sultan2. 1) Dept Biol, Okayama Univ, Quantitative Analysis of the Effects of Insulin and Tor Signalling Okayama, Japan; 2) The Grad. Sch. Nat. Sci. and Tech. Okayama on Ageing in Drosophla. Corinna Hopfen1, Nicole Philippi1, Univ. Okayama, Japan. 1,2 Linda Partridge . 1) Max-Planck Institut for Biology of Ageing, Joseph-Stelzmann-Straβe 9b, 50931, Cologne, NRW, Germany; 2) Gametogenesis and Organogenesis Institute of Healthy Ageing, and G.E.E., UCL, Gower Street, London, WC1E 6BT, UK.

360C 370A Regulatory mechanism of the nutrient-dependent expression of Histone H1 Linker-Like and Transition Proteins involved in Drosophila insulin-like peptide gene. Naoki Okamoto, Takashi chromatin condensation in Drosophila. Zain A. Alvi, Tin-Chun Nishimura. Center for Developmental Biology (CDB), RIKEN, Chu, Angela V. Klaus. Department of Biological Sciences, Seton Kobe, Hyogo, Japan. Hall University, South Orange, NJ 07079.

361A 371B The nutritional geometry of insulin shapes the landscape of aging. Genetic analysis of the spermeye region. Stephen Anderson, Stephanie Post1, Marc Tatar1,2. 1) Molecular Biology, Cell Steven Hernandez, Ujwala Gosavi, Chris Bazinet. Biological Biology and Biochemistry, Brown University, Providence, RI; 2) Sciences, St. John's University, Queens, NY. Ecology and Evolutionary Biology, Brown University, Providence, RI. 372C Nuclear and chromatin remodeling events during spermiogenesis 362B are modulated by phosphoinositide levels. Lacramioara Fabian1, Exploring the interface of endoplasmic reticulum stress and insulin Julie Brill1,2. 1) Program in Cell Biology, Hospital for Sick signal transduction. Zachary Sebo, Rahul Das, Leonard Dobens. Children, Toronto, Canada; 2) Department of Molecular Genetics, Division of Molecular Biology and Biochemistry, UMKC, Kansas University of Toronto, Toronto, M5S 1A8, Canada. City, MO. 373A 363C Essential roles for Profilin in the soma of the fly testes. Michael Genetic regulation of regeneration. Robin Harris, Joshua Saul, Fairchild, Guy Tanentzapf. Cell and Developmental Biology, Iswar Hariharan. MCB, University of California, Berkeley, University of British Columbia, Vancouver, British Columbia, Berkeley, CA. Canada.

364A 374B Interaction proteomics identify a novel translational repressor Probing glycine metabolism in Drosophila. Ujwala Ashok Gosavi, complex involved in p38MAPK-mediated control of Christopher Bazinet. St Johns University, Jamaica, Queens, NY. myoproteostasis. Vladimir Belozerov1, Helen McNeill2, Arthur Hilliker1, John McDermott1. 1) Biology, York University, Toronto, 375C ON, Canada; 2) Samuel Lunenfeld Research Institute, Mount Sinai Identification of genes involved in spermatid morphogenesis. Hospital, Toronto, ON, Canada. Dorota B. Grabowska, Arshag Mooradian, Kaushik Roychoudhury, Kathryn G. Miller. Department of Biology, 365B Washington University, 1Brookings Drive St.Louis, MO 63130. Genetic and Morphological Characterization of Male Reproductive Senescence. Michelle Giedt, Douglas Harrison. Biology 376A Department, University of Kentucky, Lexington, KY. Phosphatidylinositol 4,5-bisphosphate is required for axoneme assembly in Drosophila melanogaster spermatids. Alind Gupta1, 366C Lacramioara Fabian2, Julie Brill1,2. 1) Department of Molecular Hypoxia effects on survival, fecundity and media of Drosophila. Genetics, University of Toronto, Toronto, M5S 1A8, Canada; 2) Jon F. Harrison, Saundra Schlessinger, Taylor Biddulph, Program in Cell Biology, The Hospital for Sick Children, Toronto, Stephanie Heinrich, Nicole Holden, Katrina Ramsey. School of M5G 0A4, Canada. Life Sciences, Arizona State University, Tempe, AZ.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

377B 388A Tudor-SN interacts with Piwi in regulating spermatogenesis in Finding Novel “expressways” for gurken Translation. John W. Drosophila. Hsueh-Yen Ku1, Vamsi Gangaraju1,2, Na Liu1, Haifan Hasper, Austie F. Lawrence, Scott B. Ferguson. Biology, SUNY Lin1. 1) Stem Cell Center and Dept of Cell Biology, Yale Univ Fredonia, Fredonia, NY. School of Medicine, New Haven, CT; 2) Dept of Biochemistry and Molecular Biology, Medical Univ of South Carolina, Charleston. 389B Direct regulation of broad by the Notch pathway affects timing of 378C follicle cell development during Drosophila oogenesis. Dongyu Ectopic expression of male germline-specific RpL22e-like in Jia, Wu-Min Deng. Department of Biological Science, Florida RpL22e-depleted flies rescues embryonic lethality but causes State University, Tallahassee, FL. reduced longevity and fertility. Catherine Mageeney, Michael Kearse, Jennifer Colquhoun, Vassie Ware. Dept. of Biological 390C Sciences, Lehigh University, Bethlehem, PA 18015. Investigating Function and Composition of Follicle Cell Ring Canals in Drosophila. Ronit Kaufman1, Peter McLean1, Lynn 379A Cooley1,2,3. 1) Department of Genetics, Yale School of Medicine, Lipid signaling in spermatogenesis. Eli Miller, Geulah Ben-David, 333 Cedar Street, New Haven, CT 06520; 2) Department of Cell Josefa Steinhauer. Department of Biology, Yeshiva University, Biology, Yale School of Medicine, 333 Cedar Street, New Haven, New York, NY. CT 06520; 3) Department of Molecular, Cellular, and Developmental Biology (MCDB), Yale University, 260 Whitney 380B Avenue, New Haven, CT 06510. Analyzing the critical role of Pskl, a sperm protein, in Drosophila fertilization. Trung Phan, Barbara Wakimoto. Biology, University 391A of Washington, Seattle, WA. asteroid is required for oocyte determination and DNA repair. Julie A. Merkle, Trudi Schüpbach. HHMI/Molecular Biology, 381C Princeton University, Princeton, NJ. The testis-enriched ATP synthase subunit d paralog Ms(2)1400 is required for Nebenkern organization and elongation in Drosophila 392B spermatogenesis. Eric M. Sawyer, Lindsay Regruto, Olivia The effects of mad2 deficiency on Drosophila female meiosis. Brown, Yihharn Hwang, Lauren Ivey, Karen G. Hales. Department David M. Osiecki, William D. Gilliland. Department of Biological of Biology, Davidson College, Davidson, NC. Sciences, DePaul University, Chicago, IL.

382A 393C Functional analysis of novel dual localization AAA proteins Nmd Cbl regulates endoreplication by controlling cytoophidia. Li-Mei and CG4701 in mitochondrial, microtubule, and contractile ring Pai, Pei-Yu Wang. Dept Biochem & Molec Biol, Chang-Gung dynamics in Drosophila spermatogenesis. Bethany L. Wagner, Univ, Tao-Yuan, Taiwan. Devon E. Harris, Sarah C. Pyfrom, Jessica L. Gerard, Melissa E. Lorenzo, James J. Winkle, Karen G. Hales. Department of 394A Biology, Davidson College, Davidson, NC. Deciphering Thioredoxin function during Drosophila oogenesis. Boryana Petrova1, Zachary Whitfield1,2, Terry Orr-Weaver1,2. 1) 383B Whitehead Institute, Cambridge, MA 02142; 2) Dept. of Biology, Roles of individual subunits of the testis meiotic arrest complex in Massachusetts Institute of Technology, Cambridge, MA 02142. transcriptional control. Simona Caporilli, Robert Pickering, Daphne Davies, Helen White-Cooper. Sch Biosci, Cardiff Univ, 395B Cardiff, United Kingdom. Ectopic expression of caspase-resistant B-type lamin in the germline results in aberrant nuclear architecture and morphology 384C of mature oocytes. Alla Yalonetskaya, Elizabeth Tanner, Margaret Nuclear hormone receptor Eip78C controls ovarian germline stem Barkett, Jeanne Peterson, Kimberly McCall. Department of cell niche formation and follicle growth and survival. Elizabeth T. Biology, Boston University, Boston, MA. Ables1,2, Kelly E. Bois2, Caroline A. Garcia1, Daniela Drummond- Barbosa2. 1) Dept. of Biology, East Carolina University, 396C Greenville, NC; 2) Dept. of Biochemistry and Molecular Biology, Investigation of the Roles of Proteins that Alter Phosphorylation Johns Hopkins University School of Public Health, Baltimore, State upon Egg Activation in Drosophila melanogaster. Zijing MD. Zhang, Amber Krauchunas, Carolyn Milano, Mariana Wolfner. Molecular Biology and Genetics, Cornell University, Ithaca, NY. 385A The roles of Cyclins A, B and B3 in Drosophila female meiosis. 397A Mohammed R. Bourouh, Zhihao Guo, Rajdeep Dhaliwal, The functional and structural analysis of germline Tudor protein Sucheta Sinha. Biological Sciences, University of Windsor, complex. Ming Gao, Patrick McCluskey, Yanyan Lin, Alexey Windsor, Ontario, Canada. Arkov. Murray State University, Murray, KY.

386B 398B Sea2, a conserved SEA/GATOR2 complex component, is required A genomic analysis of doublesex (dsx) targets and function in sex for oogenesis in Drosophila. Weili Cai, Youheng Wei, John Reich, determination. E. Jimenez1, E. Clough2, C. Whitworth1,2, Y. Kim3, Mary Lilly. NICHD, National Institutes of Health, Besthesda, MD. M. Goodwin4, L. Hempel2, H. Pavlou4, Z. Chen2, D. Sturgill2, R. Dale5, H. Smith6, T. Przytycka3, S. Goodwin4, M. Van Doren1, B. 387C Oliver2. 1) JHU, Baltimore, MD; 2) Sect. Dev. Gen., Lab. Cell. Purity of essence: a new E3 ubiquitin ligase family member in Dev. Bio., NIDDK, NIH, Bethesda, MD; 3) Comp. Biol. Branch, Drosophila oogenesis. Paromita Gupta1, Christopher Bazinet1, NCBI, NLM, NIH, Bethesda, MD; 4) Dep. Phys., Anat. Gen., U Janet Rollins2. 1) Biological Sciences, St John's University, New Oxford, UK; 5) Lab. Cell. Dev. Bio., NIDDK, NIH, Bethesda, York, NY; 2) College of Mount Saint Vincent, New York, NY. MD; 6) Gen. Core, NIH, Bethesda, MD.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

399C 410B The grappa gene is target of the Doublesex transcription factors The role of Fd64a in salivary gland migration and muscle and is required for sex differentiation and gonad development. organization. Caitlin D. Hanlon. Cell Biol, Johns Hopkins Med Satish Kumar, Emily Clough, Cale Whitworth, Brian Oliver, Inst, Baltimore, MD. Doublesex Consortium. Section of Developmental Genomics, Laboratory of Cellular and Developmental Biology, National 411C Institute of Diabetes and Digestive and Kidney Diseases, National Live imaging of muscle development in akirin mutants. Katharine Institutes of Health, Bethesda, MD. Majeski, Fatima Ali, Scott Nowak. Dept. of Biology and Physics, Kennesaw State University, Kennesaw, GA. 400A Investigating the role of Sex Lethal in the germline of Drosophila 412A Melanogaster. Shekerah Primus, Mark Van Doren. Department Traffic Jam controls the architecture of the ovarian germline stem of Biology, Johns Hopkins University, Baltimore, MD. cell niche. Xi Chen, Trupti Panchal, Dorothea Godt. Dept. of Cell and System Biology, University of Toronto, Toronto, Canada. 401B Mechanism and targets of a seminal protein proteolysis cascade in 413B Drosophila. Frank W. Avila, Brooke A. LaFlamme, Kevin Snapshots of gene expression during pupal wing development lead Michalski, Mariana F. Wolfner. Dept Mol Biol & Gen, Cornell to insights about cuticle and chitin deposition. Lukasz F. Univ, Ithaca, NY. Sobala1,2, Paul N. Adler1. 1) University of Virginia, Charlottesville, VA; 2) Lodz University of Technology, Lodz, PL. 402C Nup50 is a lineage-specific nucleoporin required for germ cell 414C differentiation. Jonah Cool1, Leanne Jones2, Martin Hetzer1. 1) Matrix metalloproteinase is required for ovulation and corpus MCBL, Salk Institute, La Jolla, CA; 2) MCDB, UCLA, Los luteum formation in Drosophila. Jianjun Sun1, Lylah Deady1, Angeles, CA. Sarah Mosure1, Allan Spradling2. 1) Dept of Physiology & Neurobiology, Univ of Connecticut, Storrs; 2) Dept of 403A Embryology, Carnegie Inst for Science/ HHMI, Baltimore, MD. Identification of novel Akirin-interacting factors during embryonic myogenesis. Austin Howard, Katharine Majeski, Shelby

Johnston, Aayushi Bhagwanji, Scott Nowak. Dept. of Biology and Physics, Kennesaw State University, Kennesaw, GA. Stem Cells

404B Non-canonical roles for Yorkie, Drosophila Inhibitor of Apoptosis 415A 1, and DrICE in epithelial tube size control. Renee M. Robbins, The Hippo pathway controls follicle stem cell maintenance in the Samantha C. Gbur, Greg J. Beitel. Molecular Biosciences, Drosophila ovary. Ta-Hsing Hsu1, Jenn-Yah Yu1,2. 1) Department Northwestern Univ, Evanston, IL. of Life Sciences, Institute of Genomic Sciences, National Yang- Ming University, Taipei, Taiwan; 2) Brain Research Center, 405C National Yang-Ming University, Taipei, Taiwan. Machine learning classification of cell-specific cardiac enhancers uncovers developmental subnetworks regulating progenitor cell 1,3 416B division and cell fate specification. S. M. Ahmad , B. W. Function of Perlecan in the Drosophila Ovary. Alfonsa Diaz Busser1,3, D. Huang2,3, E. J. Cozart1, S. Michaud1, X. Zhu1, N. 1 2 1 Torres, John Pearson, Acaimo Gonzalez Reyes. Centro Andaluz Jeffries , I. Ovcharenko , A. M. Michelson . 1) NHLBI, NIH, de Biologia del Desarrollo, Sevilla, Spain. Bethesda, MD; 2) NLM, NIH, Bethesda, MD; 3) Equally contributing authors. 417C Piwi is a key regulator of the testicular stem cell niche in 406A Drosophila . Jacob M. Gonzalez, Haifan Lin. Yale Stem Cell Characterization of the Role of BTB Family Proteins in Embryonic Center, Yale University, New Haven, CT. Gonad Formation. Jennifer C. Jemc, Andrew Droste, Diane Silva, Christopher Lenkeit. Dept. of Biology, Loyola University Chicago, 418A Chicago, IL. Snail is required for maintenance of male germline stem cells. Gary R. Hime1, Aviv Gafni1, Arjun Chahal1, Agnes Gany1, Franca 407B Casagranda1, Kate L. Loveland2, Helen E. Abud2. 1) Anatomy and Cadherin 99C regulates apical expansion and cell rearrangement Neuroscience, University of Melbourne, Parkville, Victoria, during epithelial tube elongation. Se-Yeon Chung, Deborah Australia; 2) Anatomy and Developmental Biology, Monash Andrew. Dept Cell Biol, Johns Hopkins Univ, Baltimore, MD. University, Clayton, Victoria, Australia.

408C 419B The Role of tbc-1 in Drosophila Salivary Gland Development. A novel DnaJ domain protein activates integrin signaling to Dorothy M. Johnson, Deborah J. Andrew. Cell Biology, Johns maintain stem cell niche in Drosophila. Joo-Yeun Lee. University Hopkins School Medicine, Baltimore, MD. of Southern California.

409A 420C Phantom and Shade, two enzymes essential for ecdysone DNA damage disrupts stem cell-niche interaction and biosynthesis, play a critical role in the control of border cell differentiation program in the Drosophila ovary. Xing Ma1,2, migration in Drosophila. Lauren Anllo, Elena Domanitskaya, Xiaoqing Song1, Trieu Do1, Ting Xie1,2. 1) Stowers Institute for Trudi Schüpbach. HHMI/Dept. of Molecular Biology, Medical Research, Kansas city, MO; 2) University of Kansas PRINCETON UNIVERSITY, PRINCETON, NJ. Medical Center Kansas City, KS.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

432C 421A The Trithorax (Trx) histone methyl transferase complex maintains Aging-induced Notch signaling suppresses adhesiveness of neural stem cell heterogeneity in Drosophila larval brain. germline stem cells to the niche via E-cadherin. Chen-Yuan Hideyuki Komori1, Qi Xiao2, Cheng-Yu Lee1,2,3. 1) Center for Tseng1,2, Shih-Han Kao1, Chih-Ling Wan1, Yueh Cho1, Shu-Yun Stem Cell Biology, Life Sciences Institute,; 2) Depertment of Cell Tung3, Hwei-Jan Hsu1. 1) Institute of Cellular and Organismic and Developmental Biology,; 3) Division of Molecular Medicine Biology, Academia Sinica, Taipei 11529, Taiwan; 2) Graduate and Genetics, Department of Internal Medicine, University of Institute of Life Sciences, National Defense Medical Center, Taipei Michigan Medical School, Ann Arbor, MI. 11490, Taiwan; 3) Genomic Core Facility, Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan. 433A Role of p21-activated kinase Mbt in proliferation of central brain 422B neuroblasts with special focus on the mushroom body neuroblasts. Cellular and molecular regulation of stem cell niche quiescence. Juliane Melzer2, Karoline F. Kraft1, Rolf Urbach1, Thomas Leah J. Greenspan, Phylis Hetie, Erika Matunis. Cell Biology, Raabe2. 1) Institute of Genetics, University of Mainz, Mainz, Johns Hopkins School of Medicine, Baltimore, MD. Germany; 2) Institute for Medical Radiation and Cell Research, University of Würzburg, Würzburg, Germany. 423C The receptor tyrosine kinase Pvr in the Drosophila testis stem cell 434B niche. Kenneth Hammer, Judith Leatherman. Biological Drosophila Phosphotyrosyl Phosphatase Activator (PTPA) Sciences, University of Northern Colorado, Greeley, CO. Facilitates Miranda dephosphorylation in Early Mitosis and Regulates its Asymmetric Localization in Dividing Neuroblasts. 424A Fan Zhang1, Zhenxing Huang2, Hongcun Bao1, Huashan Wang3, Niche signaling regulates stem cell survival under stress-induced Yu Cai4,5, Xiaohang Yang1. 1) College of Life Sciences, Zhejiang conditions in the Drosophila testis niche. Salman Hasan, Phylis University, Hang Zhou, China; 2) Yong Loo Lin School of Hétié, Erika Matunis. Johns Hopkins Medical Institute, Baltimore, Medicine, National University of Singapore; 3) National MD. Neuroscience Institute, Singapore; 4) Temasek Life Sciences Laboratory, Singapore; 5) Department of Biological Sciences, 425B National University of Singapore, Singapore. The Jak-STAT target Chinmo prevents sex transdifferentiation of adult stem cells in the Drosophila testis. Qing Ma1, Matthew 435C Wawersik2, Erika Matunis1. 1) Cell Biology, Johns Hopkins Univ, split-ends : a novel regulator of adult stem cells in Drosophila Baltimore, MD; 2) Biology Dept, The Col of William & Mary, intestine. Maheva Andriatsilavo1, Carolina N. Perdigoto1,2, Williamsburg, VA. François Schweisguth2, Allison Bardin1. 1) Genetic and Developmental Biology unit, Institut Curie, PARIS, France; 2) 426C GDD unit, Institut Pasteur, Paris France. BMP signaling is required in the Drosophila testis cyst stem cells. James Major, Judith Leatherman. School of Biological Sciences, 436A University of Northern Colorado, Greeley, CO. Plasticity in Stem Cell Division Pattern and a Negative Feedback Slit-Robo2 Signaling Determine the Secretory EE Cell Fate in the 427A Adult Drosophila Posterior Midgut. Xiankun Zeng, Steven Hou. Apontic Functions as a Feedback Inhibitor of STAT to Maintain Stem Cell Regulation and Animal Aging Section, NCI, NIH, Niche Integrity and Limit Stem Cell Populations. Amanda J. Frederick National Laboratory, Frederick, MD. Monahan, Michelle Starz-Gaiano. Biological Sciences, University of Maryland, Baltimore County, Baltimore, MD. 437B EGFR Signaling Mediates Intestinal Stem Cell Proliferation via 428B Capicua Regulated Genes in Drosophila. Yinhua Jin, Bruce Role of Notch Signaling in Stem Cell Lineages of Testes. Chun Edgar. ZMBH-DKFZ, Heidelberg, Germany, Germany. Leung Ng, Cordula Schulz. Department of Cellular Biology, University of Georgia, Athens, GA. 438C dWDR40a regulates the mitosis-to-endoreplication transition in the 429C intestinal stem cell lineage. Jihyun Kim1, Dae-sung Hwangbo2, The Wnt signaling and cytoskeletal regulator APC2 controls stem Heinrich Jasper1,2. 1) The Buck Institute for Research on Aging; 2) cell niche size, architecture, and stem cell number in the University of Rochester. Drosophila ovary. Stacie L. Oliver, Brooke M. McCartney. Department of Biological Sciences, Carnegie Mellon University, 439A Pittsburgh, PA 15213. Regulation of pH homeostasis in the Drosophila gastrointestinal tract. Hongjie Li1,2, Yanyan Qi1, Heinrich Jasper1,2. 1) Buck 430A Institute for Research on Aging, Novato, CA, USA; 2) Department Ecdysone Regulation of Stem Cell Maintenance in the Drosophila of Biology, University of Rochester, Rochester, NY, USA. Testis Niche. Yijie Li, Qing Ma, Erika Matunis. Johns Hopkins Medical Inst, Baltimore, MD. 440B Regulation of intestinal stem cells by the Snail family 431B transcriptional repressor Escargot. Mariano A. Loza-Coll1,2, Stem cell division in the testis is affected by environmental Sharsti S. Sandall2, Tony Southall3,4, Andrea Brand3,4, D. Leanne rhythms and sleep duration. Natalia M. Tulina1, Jung Hsuan Jones1,2. 1) Molecular, Cell and Developmental Biology, Chen1, Wen-Feng Chen2, Amita Sehgal2. 1) Fox Chase Cancer University of California, Los Angeles, Los Angeles, CA; 2) The Center, Philadelphia, PA; 2) HHMI, Unviversity of Pennsylvania, Salk Institute for Biological Studies, La Jolla, CA; 3) The Gurdon Philadelphia. Institue, Cambridge, UK; 4) The University of Cambridge, Cambridge, UK.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

441C 451A Targeted control of mRNA stability reestablishes quiescence in Damage induced expression of antimicrobial peptides via the Imd Drosophila intestinal stem cells. Lindy McClelland1,2, Heinrich pathway in Drosophila larvae. Takayuki Kuraishi1,2, Aki Hori1, Jasper1, Benoît Biteau2. 1) The Buck Institute for Research on Shoichiro Kurata1. 1) Graduate School of Pharmaceutical Sciences, Aging, Novato, CA; 2) University of Rochester Medical Center. Tohoku University, Sendai, Japan; 2) PRESTO, Japan Science and Technology (JST). 442A Expression and Function of Group B Sox gene function in adult 452B intestinal stem cells. Joanna Taborda, John Nambu. Biology, Spatial and temporal variation in innate immunity. Emily Louise Florida Atlantic Univeristy, Jupiter, Fl. Behrman1, Virgina Howick2, Brian Lazzaro2, Paul Schmidt1. 1) University of Pennsylvania, Philadelphia, PA; 2) Cornell 443B University, Ithaca, NY. Regulation of String during Drosophila intestinal stem cell proliferation. Jinyi Xiang, Bruce Edgar. Cell growth and 453C proliferation, DKFZ-ZMBH Alliance, Heidelberg, Germany. Innate Immune Memory Increases Drosophila melanogaster Resistance to the Lethal Insect Pathogen Xenorhabdus 444C nematophila. Adler R. Dillman1, Marta Andres-Terre2, Brittney Adaptation of Drosophila hematopoiesis through sensory neuron Nguyen1, David S. Schneider1. 1) Department of Microbiology and stimulation. Kalpana Makhijani1, Brandy Alexander1, Sophia Immunology, Stanford, Stanford, CA; 2) Department of Petraki1, Stephanie Wachner1,4, Michael O’Connor5, Katja Immunology, Stanford, Stanford, CA. Brückner1,2,3. 1) Dept. Cell & Tissue Biol; 2) Broad Center of Regeneration Medicine and Stem Cell Research; 3) CVRI; 454A University of California San Francisco, CA; 4) University of Sting Governs An Evolutionarily Conserved Innate Immune Heidelberg, Germany; 5) Department of Genetics, Cell Biology Pathway. Alan G. Goodman, Brandon M. Kitay, Keiko Konno, and Development, University of Minnesota, Minneapolis, MN. Hiroyasu Konno, R. Grace Zhai, Glen N. Barber. University of Miami School of Medicine, Miami, FL. 445A Cell competition leads to active selection of fitter stem cells and 455B their progeny in adult homeostatic tissues. Golnar Kolahgar, Lifespan extension by promoting immune homeostasis and Saskia Suijkerbuijk, Enzo Poirier, Sarah Mansour, Benjamin limiting commensal dysbiosis in the Drosophila intestine. Linlin Simons, Eugenia Piddini. Gurdon Institute, University of Guo1,2, Jason Karpac1, Susan Tran3, Heinrich Jasper1,2,3. 1) Buck Cambridge, Cambridge, United Kingdom. Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945- 1400, USA; 2) Department of Biomedical 446B Genetics, University of Rochester Medical Center, 601 Elmwood Novel genes involved in the maintenance of hematopoietic Avenue, Rochester, NY 14642, USA; 3) Department of Biology, progenitors. Bama Charan Mondal, Cory Evans, Utpal Banerjee. University of Rochester, River Campus Box 270211, Rochester, Molecular Cell and Developmental Biology, University of NY, 14627, USA. California, Los Angeles, Los Angeles, CA. 456C 447C Low Doses of Iron-Oxide Nanoparticles have a Detrimental Effect Investigating the role of cell competition in Wnt-induced on Reproduction and Development. Benjamin W. Henderson1, tumorigenesis. Saskia JE Suijkerbuijk, Golnar Kolahgar, Hunter Dean2, Rami R. Ajjuri1, Yuping Bao2, Janis M. O'Donnell1. Eugenia Piddini. The Wellcome Trust/Cancer Research UK 1) Department of Biological Sciences, Box 870344, University of Gurdon Institute, Cambridge, United Kingdom. Alabama, Tuscaloosa, AL 35487; 2) Department of Chemical and Biological Engineering The University of Alabama Box 870203 Tuscaloosa, AL 35487-0203.

Immunity and Pathogenesis 457A Gut immune response against Gram-positive bacteria. Aki Hori1, Takayuki Kuraishi1,2, Shoichiro Kurata1. 1) Tohoku University, 448A Sendai, Japan; 2) PRESTO, Japan Science and Technology (JST). Flow cytometry in detecting blood cell populations during an immune challenge. Laura Vesala1, Ines Anderl1, Dan Hultmark1,2. 458B 1) Institute of Biomedical Technology,University of Tampere, A Drosophila immune response against RasV12-induced altered self. Robert Krautz1, Thomas Hauling2, Robert Markus1, Anne Tampere, Finland; 2) Department of Molecular Biology, 3 1 University of Umeå, Umeå, Sweden. Volkenhoff , Ulrich Theopold . 1) Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, 449B Stockholm, Sweden; 2) Karolinska Institute Science Park, The Pallbearer-SCF complex degrades RpS6 and regulates actin to SciLifeLab, Solna, Sweden; 3) Institute of Neuro- and Behavioral promote apoptotic cell clearance. Hui Xiao1, James Thompson2, Biology, University of Münster, Münster, Germany. John R. Yates Jr. III2, Nathalie C. Franc1. 1) The Department of Immunology & Microbial Science, The Scripps Research Institute, 459C La Jolla, CA; 2) Department of Chemical Physiology, The Scripps A novel dual role for Notch signaling in maintenance of Research Institute, La Jolla, CA. lamellocyte progenitors and innate immunity to parasitoid wasps in Drosophila. Chiyedza Small1,2,3, Johnny Ramroop2,3, Maria 2 2 2,3 2,3 450C Otazo , Lawrence Huang , Shireen Saleque , Shubha Govind . 1) JAK/STAT signaling in Drosophila somatic muscles is involved in Dept. of Biology, Medgar Evers College, CUNY, 1638 Bedford cellular immune response against parasitoid wasp infection. Hairu Ave, Brooklyn, NY, 11225; 2) Dept. of Biology, City College of Yang, Jesper Kronhamn, Dan Hultmark. Umeå University, Umeå, New York, CUNY, 160 Convent Avenue, NY, NY 10031; 3) The Sweden. Graduate Center, CUNY.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

460A 470B Impact of prolonged hypergravity on the immune response of An RNAi screen to identify extracellular signals required in axonal Drosophila melanogaster. William D. Wade, Sharmila targeting in the visual system. Justine Oyallon, Sergio Bhattacharya. NASA Ames, Moffett Field, CA. Astigarraga, Gina Lee, Brie Wamsley, Felix Simon, Vincent Parillaud, Jessica Treisman. New York University School of 461B Medicine, Skirball Institute of Biomolecular Medicine, New York, Physiological trade-offs during chronic infection. Moria C. NY. Chambers, Sarah Khalil, Brian P. Lazzaro. Entomology, Cornell University, Ithaca, NY. 471C Nejire/CBP regulates dendritic complexity by modulating the 462C localization of Dar1. Sarah G. Clark, Myurajan Rubaharan, M. Natural Variation Among Drosophila Melanogaster Populations in Jennifer Van, Srividya C. Iyer, Daniel N. Cox. Krasnow Institute, Response to Beauveria bassiana Exposure. Jessica Y. Chen, School of Systems Biology, George Mason University, Fairfax, Jessica I. Gabrielian, Vivian Lu, Ju-Yin Hsu, Mishan D. VA. Rambukwella, Matthew Salomon, Daniel Campo. Molecular and Computational Biology, University of Southern California, Los 472A Angeles, CA. Dissecting the role of autophagy in mediating sensory neuron dendrite homeostasis. Lacey Graybeal, Srividya C. Iyer, Eswar P. 463A R. Iyer, Caroline Thomas, Myurajan Rubaharan, Daniel N. Cox. Effects of Metabolism and Stress on Immune Defense: Krasnow Institute, School of Systems Biology, George Mason Investigating the Molecular Crosstalk between Metabolism, Stress, University, Fairfax, VA. and the Immune System. Katia Sotelo-Troha1, Nicolas Buchon2, Brian Lazzaro2. 1) Department of Biological & Biomedical 473B Sciences, Cornell University, Ithaca, NY; 2) Department of Silencing of the Drosophila ortholog of SOX5 in neurons leads to Entomology, Cornell University, Ithaca, NY. impaired dendrite differentiation and olfactory perception. Airong Li, Adele Bubnys, Rebecca Tate, Rudolph Tanzi. Genetics and 464B Aging Research Unit, MassGeneral Institute for Factors that influence Wolbachia titer in Drosophila simulans and Neurodegenerative Diseases, Massachusetts General Hospital and Drosophila melanogaster. Marissa Cloutier, Jack Manquen, Harvard Medical School, Charlestown, MA. Roger Albertson. Biology Dept, Albion College, Albion, MI. 474C 465C FoxO regulates dendritic morphology and MT organization. James The impact of nutrients on intracellular Wolbachia titer. Laura R. Sears, Heather Broihier. Neurosciences, Case Western Reserve Serbus1, Pamela White2, Roger Albertson3, Amanda Rabe2, University, Cleveland, OH. William Sullivan2. 1) Biological Sciences, OE210, Florida International University, Miami, FL; 2) MCD Biology, Sinsheimer 475A 319, University of California, Santa Cruz, CA; 3) Biology Balancing dendrite-epidermis and dendrite-ECM interactions for Department, Putnam 262, Albion College, Albion, MI. dendrite morphogenesis. Conrad M. Tenenbaum, Mala Misra, Elizabeth Gavis. Molecular Biology, Princeton University, 466A Princeton, NJ. Genome-wide RNAi screen for host factors that regulate Wolbachia titer. Pamela M. White1, Laura R. Serbus2, William 476B Sullivan1. 1) Molecular, Cell, and Developmental Biology Sexual identity affects the development and mature function of a University of California, Santa Cruz 1156 High Street Santa Cruz, defined neural circuit in Drosophila melanogaster. Parag Bhatt, CA 95064; 2) Department of Biological Sciences, OE210 Florida Harsha Swamy, Selma Avdagic, Wendi Neckameyer. International University 11200 SW 8th St Miami, FL 33199. Pharmcological and Physiological Science, Saint Louis University School of Medicine, St Louis, MO.

477C Neural Development Collapsin response mediator protein (CRMP) is required for presynaptic development in R7 photoreceptor neurons. Sarah Casper, Tory Herman. Institute of Molecular Biology, University 467B of Oregon, Eugene, OR. An RNAi screen identifies a new determinant of R7 photoreceptor axon targeting. Jessica Douthit, Sergio Astigarraga, Jessica 478A Treisman. Department of Cell Biology and Kimmel Center for The transmembrane domain of Neto engages the glutamate Biology and Medicine at the Skirball Institute, New York receptors and enables their clustering at the Drosophila NMJ. Qi University School of Medicine, New York, NY. Wang, Young-Jun Kim, Oghomwen Igiesuorobo, Mihaela Serpe. NICHD/NIH,Bethesda,MD. 468C Slit/Robo-mediated axon guidance in Tribolium and Drosophila. 479B Tim Evans. Biological Sciences, University of Arkansas, Expression profiling of R7 and R8 photoreceptors during Fayetteville, AR. development of the D. melanogaster eye. Stefan A. Koestler, Arzu Celik-Fuss. Department of Molecular Biology and Genetics, 469A Bogazici University, Istanbul, Turkey. The Drosophila formin dDAAM is required for axon growth in the developing mushroom body. Rita Gombos, József Mihály. Biological Research Centre, Hungarian Academy of Sciences, Szeged, Csondrad, Hungary.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

480C Davis1, Mark A. Melton2, Rachana R. Chandran3, Napoleon Studying the eye differentiation in the Drosophila transcriptome. Butler1, Lan Jiang3. 1) Dept of Biological Sciences, North Carolina Manon Quiquand1, Nicholas E. Baker1, Dachuan Zhang1, Jackie State Univ, Raleigh, NC; 2) Dept of Biological and Physical Han2, Shengbao Suo2, Nan Qiao2, Matthew Slattery3, Kevin Sciences, Saint Augustine's Univ, Raleigh, NC; 3) Dept of White3. 1) Albert Einstein College of Medicine, Bronx, NY; 2) Biological Sciences, Oakland University, Rochester, MI. Institute for Computational Biology, Shanghai; 3) Institute for Genomics and System Biology, Chicago, IL. 489C Investigating the effect of Odd-skipped (Odd) loss-of-function on 481A neuronal specification in Drosophila melanogaster. Mena Farag, Combinatorial rules of precursor specification underlying olfactory Camilla Larsen, Peter Levy. MRC Centre for Developmental neuron diversity. Pelin C. Volkan1,2,3, Qingyun Li1, Tal Soo HA4, Neurobiology, King's College London, London, United Kingdom. Sumie Okuwa1, Yiping Wang1, Qian Wang5, S. Sean Millard6. 1) Department of Biology, Duke University, Durham, NC; 2) 490A Department of Neurobiology, Duke University, Durham, NC; 3) Investigating the molecular mechanism of Crimpy-mediated Duke Institute of Brain Sciences; 4) Department of Biomedical presynaptic Gbb signaling at the NMJ. Kendall Hoover, Rebecca Science, College of Natural Science, Daegu University, 15 Naeri, James, Heather Broihier. Department of Neurosciences, Case Jillyang, Gyeongsan, Gyeongbuk 712-714, South Korea; 5) The Western Reserve University School of Medicine, Cleveland, OH Pratt School of Engineering, Duke University, Durham, NC; 6) 44106. School of Biomedical Sciences, The University of Queensland, BNE, QUEENSLAND. 491B Characterizing a novel FoxO-dependent neurotrophic pathway. 482B Colleen McLaughlin, Heather Broihier. Neurosciences, Case Genetic interaction of alan shepard (shep) in neuronal remodeling Western Reserve University , Cleveland , OH. during metamorphosis. Dahong Chen, Randall Hewes. Department of Biology, University of Oklahoma, Norman, OK. 492C Connecting dCORL CNS expression and behavioral defects in 483C dCORL mutants. Norma Takaesu1, Agapi Dimitriadou2, Janine Lineage-related neuronal wiring properties of the Drosophila brain. Quijano1, Estela Arciniega1, Nancy Tran1, Carsten Duch3, Christos Volker Hartenstein1, Jennifer Lovick1, Stephan Saalfeld2, Pavel Consoulas2, Stuart Newfeld1. 1) Sch Life Sci, Arizona State Univ, Tomancak2, Albert Cardona3. 1) MCDB, UCLA, Los Angeles, CA; Tempe, AZ; 2) Lab Experimental Physiology, Univ. Athens 2) Max Planck Institute of Molecular Cell Biology and Genetics, Medical School, Athens, Greece; 3) Inst. Neurobiology, Johannes Dresden, Germany; 3) Janelia Farm Research Campus, Howard Gutenberg Univ. Mainz, Germany. Hughes Medical Institute, Ashburn, Virginia, USA. 493A 484A Characterizing the Role of E-cadherin in Neuroblast Maintenance. Linking cell surface receptor to microtubule: Tubulin folding Alexis A. Reyes. Vanguard University, Costa Mesa, CA. cofactor D mediates Dscam functions during neuronal morphogenesis. Misako Okumura1, Chisako Sakuma1, Masayuki 494B Miura1,2, Takahiro Chihara1,2. 1) Department of Genetics, Graduate Characterization of Group B Sox genes in Development of Adult School of Pharmaceutical Sciences, University of Tokyo; 2) Core Nervous System. Shweta Singh, John Nambu. Biology, Florida Research for Evolutional Science and Technology, Japan Science Atlantic University, Jupiter, FL. and Technology Agency. 495C 485B Multi-potent Intermediate Progenitor Cells Are Present Analysis of Retinal Basal Glial cell Drivers from Janelia Gal4 Throughout All Pupa Stage In Drosophila melanogaster. Elizabeth Lines in Drosophila Melanogaster. Yen-Ching Chang1,2, Y. Henry R. Swezey. Vanguard University, Costa Mesa, CA. Sun1,2. 1) Instituition of Moleuclar biology, Sinica, Taipei, Taipei, Taiwan; 2) Department of Life sciences and Institute of Genome sciences, National Yang-Ming University, Taipei, Taiwan, Republic of China. Neurophysiology and Behavior

486C RNAi screening for investigation of retinal basal glia development. 1,2 1,2 496A Tsao Chia-Kang , Sun Y. Henry . 1) Institute of Molecular Dopamine homeostasis is essential for daily activity and movement Biology, Academia Sinica, Taipei, Taiwan, Republic of China; 2) behavior in Drosophila melanogaster - a model system to study Department of Life Sciences and Institute of Genome Sciences, neurological disorders. Anathbandhu Chaudhuri1, Courtney National Yang-Ming University, Taipei, Taiwan, Republic of Cunningham1, Mary Jane Krotzer1, Janis O'Donnell2, Natraj China. Krishnan3. 1) Department of Natural Sciences, Stillman College, Tuscaloosa, AL; 2) Biological Sciences, University of Alabama, 487A Tuscaloosa, 35487, AL; 3) Department of Biochemistry, Remodeling of peripheral glial ensheathment during Mississippi State University, MS 39762. metamorphosis - a role for the EGF signaling pathway. Matthew Siefert, Soumya Banerjee, Hayley Gibson, Tara Fallah, Joyce 497B Fernandes. Department of Zoology, Miami University, Oxford, Changes in Acetylcholine Release Alter Locomotion and Touch OH. Response Timing in Drosophila. Gabriel Gutierrez1, David Krantz1, Natalie Kendall2, Toshi Kitamoto3, Hakeem Lawal1,2. 1) 488B Department of Psychiatry, David Geffen School of Medicine at A Comparison of Midline and Tracheal Gene Regulation during UCLA, Los Angeles CA; 2) Neuroscience Program, Department of Drosophila Development. Patricia A. Estes1, Sarah K. R. Long1, 1 1 1 Biology, Delaware State University, Dover 3) Department of Eric Fulkerson , Rebecca Breese , Giovanna Hernandez , Cara Anesthesia, Carver College of Med, University of Iowa, Iowa City.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

498C 507C The endosomal Hook protein is required for histamine recycling in Localization of aversive gustatory memory. Kurtresha Worden1, the Drosophila visual system. Mokhlasur Rahman, Helmut Yoshi Aso2, Gerald Rubin2, Alex Keene1, Pavel Masek1. 1) Kramer. Department of Neuroscience, UT Southwestern Medical University of Nevada, Reno, Sparks, NV; 2) HHMI JFRC, Center at Dallas, Dallas, TX. Ashburn, VA.

499A 508A Control of Body Size by TGF-Beta Signaling. Lindsay Moss- Male-Specific Fruitless Isoforms Target Neurodevelopmental Taylor1, Michael O'Connor2. 1) Molecular, Cellular, Genes to Specify a Sexually Dimorphic Nervous System. Megan Developmental Biology and Genetics Program, University of C. Neville1, Tetsuya Nojima1, Elizabeth Ashley1, Darren Parker2, Minnesota, Minneapolis, MN; 2) Department of Genetics, Cell Tony Southall3, Andrea Brand3, Steven Russell4, Michael Ritchie2, Biology and Development, University of Minnesota, Minneapolis, Stein Aerts5, Stephen Goodwin1. 1) Physiology, Anatomy and MN. Genetics, University of Oxford, Oxford, United Kingdom; 2) Centre for Biological Diversity, University of St Andrews, St 500B Andrews; 3) The Gurdon Institute and Department of Physiology, Determination of the location of action of isoflurane in the Development and Neuroscience, University of Cambridge; 4) Drosophila brain. Christina M. Colosimo1, Anna James1, Krista Department of Genetics, University of Cambridge, Downing Pearman1, Michelle Peters2, Michael J. Murray3, Gerald B. Call1. Street, Cambridge; 5) Laboratory of Computational Biology, 1) Arizona College of Osteopathic Medicine, Midwestern Department of Human Genetics, University of Leuven. University, Glendale, AZ; 2) Glendale Community College, Glendale, AZ; 3) Dept of Anesthesiology, Scottsdale, AZ. 509B Investigation into the molecular-genetic basis of Drosophila 501C melanogaster female post-mating behaviors. Nicole R. Newell1, Photoreceptor neuron function requires a conserved Ncc69- Joyce L. Kao2, Kjong-Van Lehmann2, Karrie D. Dudek1, activating kinase cascade specifically in glia. Drew Stenesen1, Christopher L. Souders1, Peter Poon2, Daniel Campo2, Matthew Jeffrey Schellinger2, Aylin Rodan2, Helmut Krämer1. 1) Salomon2, Peter L. Chang2, Tevfik Hamdi Kitapci2, Justin M. Department of Neuroscience, UT Southwestern Medical Center, Fear3, Justin E. Dalton1, Alison M. Morse3, Simon Tavaré2, Lauren Dallas, Texas; 2) Department of Internal Medicine, UT McIntyre3, Sergey Nuzhdin2, Michelle N. Arbeitman1. 1) Southwestern Medical Center, Dallas, Texas. Department of Biomedical Sciences, Florida State University, Tallahassee, FL; 2) Molecular and Computational Biology, 502A University of Southern California, Los Angeles, CA; 3) Minibrain kinase promotes efficient synaptic vesicle recycling. Department of Molecular Genetics and Microbiology, University Chun-Kan Chen1,2, Catherine Bregere1, Jeremy Paluch3, Dion of Florida, Gainesville, FL. Dickman3, Karen Chang1,4. 1) Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA; 2) Dept. 510C Biochemistry & Molecular Biology, University of Southern Modeling the circadian oscillator protein network in Drosophila California, Los Angeles, CA; 3) Dept. of Neurobiology, University melanogaster. Vu Lam, Ying Li, Jonathan Diehl, Joanna Chiu. of Southern California, Los Angeles, CA; 4) Dept. Cell & Entomology and Nematology, UC Davis, Davis, CA. Neurobiology, University of Southern California, Los Angeles. 511A 503B A novel Bayesian approach to social structure uncovers cryptic An EP Overexpression Screen for Genetic Modifiers of rab7- regulation of group dynamics. Brad R. Foley1, Julia B. Salz1, Dependent Neurodegeneration in Drosophila Nervous System. Sergey V. Nuzhdin1, Paul Marjoram2. 1) Molecular and Wei-Hung Jung1, Smita Cherry2, Jennifer Jin2, Robin Hiesinger2, Computational Biology, University of Southern California, Los Chih-Chiang Chan1. 1) Department of Physiology, National Angeles, CA; 2) Keck School of Preventative Medicine, University Taiwan University, Taipei, Taiwan; 2) Department of Physiology, of Southern California, Los Angeles, CA. University of Texas Southwestern Medical Center, Dallas, TX, USA. 512B The blood-brain barrier regulates ecdysone signalling in the CNS, 504C affecting neurophysiology and behaviour. Samantha Hindle1, The domain of synaptotagmin implicated in autoimmunity is not Souvinh Orng1, Michael DeSalvo1, Elena Dolgikh2, Hiroshi required for synaptic function. Michael D. Getzy1, Carin A. Ishimoto3, Fahima Mayer1, Toshihiro Kitamoto3, Matt Jacobson2, Loewen2, Laurie M. Biela1, Noreen E. Reist1. 1) Biomedical Roland Bainton1. 1) Department of Anesthesia, University of Sciences, Colorado State University, Fort Collins, CO; 2) Genetics, California San Francisco, CA; 2) Department of Pharmaceutical University of Wisconsin, Madison, WI. Chemistry, University of California San Francisco, CA; 3) Department of Anesthesia, University of Iowa, IA. 505A Functional Role of Mushroom Body Neurons in Courtship 513C Conditioning. Shelby A. Montague, Yoshinori Aso, Gerald M. Screening for a receptor for the Drosophila seminal fluid protein, Rubin, Bruce S. Baker. HHMI Janelia Farm Research Campus, ovulin. Jennifer Apger McGlaughon, Brooke A. LaFlamme, Ashburn, VA. Mariana F. Wolfner. Cornell University, Ithaca, NY.

506B 514A A novel role for Notch signaling in alcohol reward memory. Arjun Steroid signaling modulates nociception in Drosophila Ray1, Reza Azanchi2, Yoshi Aso3, Gerry Rubin3, Ulrike melanogaster. Aidan L. McParland, Mona Roesler, Geoffrey K. Heberlein3, Karla Kaun2. 1) Molecular Biology, Cell Biology and Ganter. Biology, University of New England, Biddeford, ME. Biochemistry, Brown University, Providence, RI; 2) Neuroscience , Brown University, Providence, RI; 3) HHMI Janelia Farm Research Campus, Ashburn, VA.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

515B 526A Ecdysis Triggering Hormone acts on neurons to both positively Dopaminergic pathways innervating Mushroom Bodies are and negatively regulate wing expansion. Rebecca Vaadia, Feici involved in olfactory responses in Drosophila melanogaster. Diao, Benjamin H. White. Laboratory of Molecular Biology, Nicolás Fuenzalida-Uribe, Jorge M. Campusano. Departamento NIMH, Bethesda, MD. de Biología Celular y Molecular, Universidad Católica de Chile, Santiago, Chile. 516C Ecdysteroid plays a role in Drosophila nociception. Gwendolyn 527B Davis Vesenka, Geoffrey K. Ganter. Biology Department, Genome-wide Association Mapping of Natural Variation in Odor- University of New England, Biddeford, ME. guided Behavior in Drosophila. Elizabeth B. Brown1, John E. Layne1, Cheng Zhu2, Anil G. Jegga3,4, Stephanie M. Rollmann1. 1) 517A Department of Biological Sciences, University of Cincinnati, Behavioral Analysis of the Pruritus Response in Drosophila Cincinnati, OH; 2) Department of Computer Science, University of melanogaster. Ciny John, Edward Kempf, John Nambu. Cincinnati, OH; 3) Division of Biomedical Informatics, Cincinnati Department of Biological Sciences, Charles E. Schmidt College of Children's Hospital Medical Center, Cincinnati, OH; 4) Science, Florida Atlantic University, Jupiter, FL. Department of Pediatrics, University of Cincinnati, Cincinnati, OH. 518B Roles for jim lovell in larval feeding behavior and embryonic 528C development. Kathleen M. Beckingham, Fanli Zhou, Cheng Molecular and Physiological Characterization of Drosophila Wang. Dept Biochem & Cell Biol, Rice Univ, Houston, TX. melanogaster 4th Order Olfactory Neurons. Amanda J. Crocker1,2, Coleen Murphy2,3, Mala Murthy1,2. 1) Princeton 519C Neuroscience Institute, Princeton University, Princeton, NJ; 2) Quantitative Genetics of Food Intake in Drosophila melanogaster. Molecular Biology, Princeton University, Princeton, NJ; 3) Lewis Megan Garlapow1, David Threadgill2, Trudy Mackay1. 1) Sigler Institute, Princeton University, Princeton, NJ. Program in Genetics, Dept of Biological Sciences, College of Science, North Carolina State Univ, Raleigh, NC; 2) Dept of 529A Veterinary Pathobiology, Texas A&M Univ, College Station, TX. Variation in epistatic interactions that modify olfactory behavior in the Drosophila melanogaster Genetic Reference Panel. Xiaofang 520A He1,2, Shanshan Zhou1, Genevieve E. Evans1, Trudy F. C. The Anatomy and Function of Enteric Neurons. Marion Hartl, Mackay1, Robert R. H. Anholt1. 1) Biological Sciences, North Dafni Hadjieconomou, Irene Miguel-Aliaga. Gut Signalling and Carolina State University, Raleigh, NC; 2) Department of Metabolism, MRC Hammersmith Campus, London, United Entomology, South China Agricultural University, Guangzhou Kingdom. 510642, China.

521B 530B Selection for starvation resistance promotes sleep and inhibits Inhibition and activation of key olfactory pathways promotes both foraging behaviors in Drosophila. Pavel Masek1, Lauren attraction and avoidance. Dyan MacWilliam, Anandasankar Ray. Reynolds2, Wesley Bollinger1, Catriona Moody1, Aradhana Dept. of Entomology, University of California, Riverside, CA. Mehta1, Allen Gibbs2, Alex Keene1. 1) Dept of Biology, University of Nevada, Reno, NV; 2) School of Life Sciences, 531C University of Nevada, Las Vegas, NV, 89154. Conservation of innate olfactory avoidance pathways across Drosophila species. Christine K. Pham1, Anandasankar Ray2. 1) 522C Interdepartmental Neuroscience Program, University of California, Neural translin Regulates Metabolic Control of Sleep. Maria E. Riverside, Riverside, CA; 2) Entomology Department, University Yurgel1, Kaz Murakami1, Aradhna Mehta1, Justin DiAngelo2, of California, Riverside, Riverside, CA. Pavel Masek1, Alex C. Keene1. 1) University of Nevada, Reno, 1664 N. Virginia Street, Reno, NV 89557; 2) Hofstra University, 532A 900 Fulton Avenue, Hempstead, NY, 11549. Acids modulate bitter and sweet taste in Drosophila. Yan Chen, Hubert Amrein. Molecular and Cellular Medicine, Texas A&M 523A Health Science Center, College Station, TX. Acute hypergravity alters locomotor behavior and causes physiological stress in Drosophila melanogaster. Ravikumar 533B Hosamani1, Jarret Weinrich2, Curran Reddy1, Sharmila Molecular Basis of Sugar Sensing in Drosophila. Ahmet E. Bhattacharya1. 1) NASA Ames Research Center, Mountain View, Yavuz1, Shinsuke Fujii1, Christopher Jagge1, Jesse Slone2, CA; 2) Weill Medical College of Cornell University, NY. Xiangyu Song3, Hubert Amrein1. 1) Molecular & Cellular Medicine, Texas A&M HSC, College Station, TX; 2) Department 524B of Biology, Vanderbilt University, Nashville, TN; 3) P&G BJTC, Intracellular calcium signaling specifies dopaminergic neurons Beijing, China. required for wing coordination during Drosophila flight. Sufia Sadaf, Sanjay Sane, Gaiti Hasan. National Centre for Biological 534C Sciences, TIFR, Bangalore-560065, India. Distinct neuronal circuits regulate sleep and wake within Drosophila mushroom body. Nan Chen1, Divya Sitaraman1,2, 525C Yoshinori Aso1, Wyatt Korff1, Michael Nitabach1,2, Gerald Rubin1. stallone and balboa are DEG/ENaC genes required for mechanical 1) Howard Hughes Medical Institute Janelia Farm Research nociception in Drosophila larvae. Stephanie Mauthner1, Richard Campus, Ashburn, VA; 2) Yale University School of Medicine, Hwang2, Qi Xiao2, W. Daniel Tracey1,2,3. 1) Univ Prog Genetics Dept. of Cellular and Molecular Physiology, New Haven, CT and Genomics, Duke University, Durham, NC; 2) Department of 06511. Neurobiology, Duke University, Durham, NC; 3) Department of Anesthesiology, Duke University Medical Center, Durham, NC.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

535A 544A A Hard-wired Glutamatergic Circuit Pools and Relays UV Signals A Drosophila Brain Tumor Model to Study Interclonal to Mediate Spectral Preference in Drosophila. Thangavel Interactions. Austin Roebke3, Indrayani Waghmare1, Madhuri Karuppudurai1, Tzu-Yang Lin1, Benjamin White2, Marco Gallio3, Kango-Singh1,2,3. 1) Department of Biology, University of Dayton, Thomas Pohida4, Chi-Hon Lee1. 1) NIH/NICHD, Bethesda, MD; Dayton, OH 45469; 2) Center for Tissue Regeneration and 2) NIH/NIMH, Bethesda, MD; 3) Northwestern University, Engineering at Dayton (TREND), University of Dayton, Dayton, Evanston, IL; 4) NIH/CIT, Bethesda, MD. OH 45469; 3) Premedical Programs, University of Dayton, Dayton, OH 45469. 536B CO2 Effects on Subsequent Anesthesia. Nathan R. 545B Bartholomew1, Gerald B. Call2. 1) Biomedical Sciences, Dm-Myb regulation of cell cycle genes is independent of NURF. Midwestern University, Glendale, AZ; 2) Dept of Pharmacology, Juan Santana1, Mrutyunjaya Parida2, Abby Long3, Jonathan Arizona College of Osteopathic Medicine, Midwestern University, Birdsall3, Kealie Rogers3, Martin Aguilera3, Kar Men Mah3, Scott Glendale, AZ. McDermott3, J. Robert Manak1,2,3,4. 1) Interdisc Grad Program in Genetics, University of Iowa, Iowa City, IA; 2) Interdisc Grad 537C Program in Informatics; 3) Dept Biology; 4) Dept Pediatrics, Sucrose-only diets suppress seizure-like activity (SLA) and shorten Carver College of Medicine. recovery time following SLA in the Bang-sensitive (BS) paralytic mutants easily-shocked and technical knockout. Kris Burner, 546C Daniel Kuebler. Biology, Franciscan University, Steubenville, OH. Screening of medicinal plant extracts from Nepal, in cancer models of Drosophila. Bhupal G. Shrestha1,2, Parthiv H. Patel2, Bruce 538A Edgar2. 1) Biotechnology, Kathmandu University, Dhulikhel, Contrasting influences of Drosophila white/mini-white on ethanol Kathmandu, Nepal; 2) DKFZ-ZMBH Alliance, University of sensitivity in two different behavioral assays. Robin Chan1,2, Heidelberg, Germany. Jacquie Delohyt2,3, Lara Lewellyn2, Matt Hewitt2, Kristyn Sennett2, Scarlett Coffman2, Jill Bettinger4,5, John Warrick6, Mike 547A Grotewiel1,2,3,5. 1) Molecular Biology and Genetics Program; 2) Identification and characterization of cancer-relevant genes in a Human and Molecular Genetics; 3) Neuroscience Program; 4) Drosophila tumor model. Janine Toggweiler, Maria Willecke, Pharmacology and Toxicology; 5) Virginia Commonwealth Konrad Basler. Institute of Molecular Life Sciences, University of University Alcohol Research Center, Virginia Commonwealth Zurich, Zurich, Switzerland. University, Richmond, VA; 6) Department of Biology, University of Richmond, Richmond, VA. 548B Size and Growth Regulation in Development and Cancer. Tian 539B Xu, Chiswili Chabu, Sangil Lee. Dept Gen, HHMI, Yale Univ, Directional Preference in Drosophila. Taylor A. James, Eli D. New Haven, CT. Zachary, Spicie M. Davis, Michael J. Baltzley, Kristin L. Latham. Western Oregon University, Monmouth, OR. 549C Diverse transcriptional cardiac aging profiles lead to similar 540C decline in heart function. Leah Cannon1, Anthony Cammarato1, Systematic Profiling and Functional Characterization of rab Sanford Bernstein2, Alexander Zambon2, Rolf Bodmer1. 1) GTPases in Drosophila Brain and Malpighian Tubules. Cheng- Development and Aging, Sanford-Burnham Medical Research Wen Hsieh1, Chung-Chih Liu1, Smita Cherry3, Jennifer Jin3, June- Institute, La Jolla, CA; 2) University of California, San Diego. Tai Wu2, Robin Hiesinger3, Chih-Chiang Chan1. 1) Graduate Institute of Physiology, National Taiwan University, Taipei, 550A Taiwan; 2) Graduate Institute of Molecular Medicine, National Tau-induced mitochondrial dysfunction mediates cardiomyopathy Taiwan University, Taipei, Taiwan; 3) Department of Physiology, in Drosophila model. Sreehari Kalvakuri1, Adriana Trujillo2, UT Southwestern Medical Center, Dallas, Texas, USA. Sanford I. Bernstein2, Rolf Bodmer1, Girish C. Melkani2. 1) Aging and Development Program, Sanford Burnham Medical Research Institute, San Diego, CA 92037; 2) Department of Biology,

Molecular Biology and SDSU Heart Institutes, San Diego State Drosophila Models of Human Diseases University San Diego, CA 92182.

551B 541A Cardiac Remodeling Mechanisms. Karen Ocorr. Dept The JAK-STAT signaling pathway mediates the effects of ethanol Neuroscience & Aging, Burnham Inst Medical Research, La Jolla, on development and adult behavior. Kimberly D. McClure, Gina CA. Trotto, Gabriella Ceresa, Maria Barajas, Joseph Skopek. Department of Biology, Elmhurst College, Elmhurst, IL. 552C Drosophila heart model to study the genetic basis underlying 542B Ischemia/Reperfusion-induced cardiac injury: Combinatorial Targeting the Spindle Assembly Checkpoint gene, Mad2, and function of Hif1α and Hsp23. Sarah Piloto, Rolf Bodmer. small molecule inhibitors using synthetic lethality. Shamim A. Development and Aging, Sanford-Burnham Medical Research Butt, Blake Riggs. San Francisco State University, 1600 Holloway Institute, La Jolla, CA. Ave, San Francisco, CA. 553A 543C Methylene blue as a therapeutic compound in Drosophila models Cachexia-like Wasting Induced by Malignant Tumors in of Huntington’s disease. Herve Tricoire, Raheleh Heidari, Elodie Drosophila. Alejandra Figueroa-Clarevega, David Bilder. Martin, Veronique Monnier, Amandine Palandri. Unité de Biologie Molecular and Cell Biology, UC Berkeley, Berkeley, CA. Fonctionnelle et Adaptative (BFA, Univ Paris Diderot, Sorbonne Paris Cité, PARIS, France.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Behavioral and Developmental Genetics, VIB Center for the 554B Biology of Disease, University of Leuven, Leuven, Belgium; 3) Modeling Ceramide-Induced Lipotoxic Cardiomyopathy. Stanley Neuroscience Department, Janssen Research and Development, a M. Walls1, Greg L. Harris2, Rolf Bodmer1. 1) Development, Aging Division of Janssen Pharmaceutica NV, Beerse, Belgium. and Regeneration Program, Sanford-Burnham Med. Res. Institute, San Diego, CA; 2) Department of Biology, San Diego State 563B University, San Diego CA. A Drosophila model of neurometabolic disease yields insights into therapeutic treatments for Adrenoleukodystropy. Hannah B. 555C Gordon, Anthea Letsou. Department of Human Genetics, Characterization of sialic acid synthase mutants rescued by a University of Utah, Salt Lake City, UT. transgene expressed in the insulin producing cells: loss of sialic acid in IPC cells is a model for Type II diabetes. Aiden Nguyen, 564C Ilhan Akan, John Nguyen, Karen Palter. Biology, Temple Proteotoxicity in Drosophila: Relevance of the Drosophila Tau University, Philadelphia, PA. Protein. Marianna K. Gorsky1,2, Sylvie Burnouf1, Sebastian Grönke1, Jacqueline Dols1, Linda Partridge1,2. 1) Max Planck 556A Institute for Biology of Ageing, Cologne, NRW, Germany; 2) Phytochemical Withanolide A (WL-A) : A potent suppressor of Cologne Excellence Cluster on Cellular Stress Responses in Aging Huntington's disease in transgenic Drosophila model. Namita Associated Diseases (CECAD), University of Cologne, Cologne, Agrawal, Chongtham Anjalika. Dept of Zoology, University of Germany. Delhi, Delhi, India. 565A 557B Investigating genetic interactions between proteins in the PI3K- Juvenile Exposure to the Herbicide Paraquat Result in Long-Term AKT signaling pathway and molecular motors. Timothy Hansen, Consequences in Parkinson's Disease. Rami R. Ajjuri, James Shermali Gunawardena. Biological Sciences, University at Anderson, De'Anna Trunnell, Ryan Colaianni, Janis O'Donnell. Buffalo, Buffalo, NY. Biological Sciences, University of Alabama, Tuscaloosa, AL. 566B 558C Role of Calcium channels in fungal volatile organic compound- PI3K-induced Synaptogenesis Prevents β-Amyloid Neurotoxicity. mediated neurotoxicity. Arati A. Inamdar, Joan W. Bennett. Mercedes Arnés1, Sergio Casas-Tintó1, Ángel Acebes1,2, Alberto Department of Plant Biology and Pathology, Rutgers, The State Ferrús1. 1) Cajal Institute, Madrid, Spain; 2) Centro de University of New Jersey, New Brunswick, NJ. Investigaciones Biomédicas de Canarias (CIBICAN) La Laguna, Tenerife, Spain. 567C Drosophila eye model to understand role of signaling pathways in 559A Aβ42 mediated neurodegeneration. Madison N. Irwin1, Kristine Dexamethasone induces heat shock response and slows down Garcia1, Madhuri Kango-Singh1,2,3, Amit Singh1,2,3. 1) Department disease progression in mouse and fly models of Huntington’s of Biology, University of Dayton, 300 College Park Drive, Dayton, disease. Megha Maheshwari1, Supriya Bhutani1, Aniruddha Das1, OH; 2) Premedical Program, University of Dayton, 300 College Rajarshi Mukherjee1, Ankit Sharma1, Yoshihiro Kino2, Nobuyuki Park Drive, Dayton, OH; 3) Center for Tissue Regeneration and Nukina2, Nihar Jana1. 1) National Brain Research Centre, Gurgaon, Engineering at Dayton (TREND), University ofDayton, Dayton, Haryana, India; 2) Structural Neuropathology Laboratory, Riken OH. Brain Science Institute, Wako-shi, Saitama-351-0198, Japan. 568A 560B MULAN E3 ligase interacts with PINK1 in regulating Characterization of dnr1 in Drosophila: linking innate immune mitochondrial dynamics and mitophagy in a Drosophila response to neurodegeneration. Yang Cao1, Stanislava Parkinson’s disease model. Sreehari Kalvakuri1, Ryo Yonashiro2, Chtarbanova-Rudlof1, Andrew Petersen2, Barry Ganetzky1. 1) Zhihao Wu3, Bingwei Lu3, Claudio Joazeiro2, Rolf Bodmer1. 1) Laboratory of Genetics, University of Wisconsin-Madison, Development and aging program, Sanford Burnham Medicalsearch Madison, WI; 2) Molecular and Cellular Pharmacology Program, Institute, San Diego, CA; 2) Department of Cell Biology, The University of Wisconsin-Madison, Madison, WI. Scripps Research Institute, CB168, 10550 North Torrey Pines Road, La Jolla, California 92037, USA; 3) Department of 561C Pathology, Stanford University School of Medicine, Stanford, Role of Transcriptional Co-Activator CREB Binding Protein in California 94305, USA. Amyloid Beta 42 Mediated Neurodegeneration. Timothy L. Cutler1,2, Oorvashi Roy Puli3, Meghana Tare3, Michael T. Moran3, 569B Greg Mancini3, Madhuri Kango-Singh1,3,4, Amit Singh1,3,4. 1) A non-neural Drosophila model for NMDA receptor-mediated Premedical Programs, University of Dayton, 300 College Park excitotoxic cell death. Michael Lehmann, Brandy Ree. Dept Drive, Dayton, OH; 2) University Honors Program, University of Biological Sci, Univ Arkansas, Fayetteville, AR. Dayton, 300 College Park Drive, Dayton, OH; 3) Department of Biology, University of Dayton, 300 College Park Drive, Dayton, 570C OH; 4) Center for Tissue Regeneration and Engineering at Dayton Mitochondrial induced oxidative damage in neurons activates JNK (TREND), University of Dayton, 300 College Park Drive, Dayton, and SREBP, induces lipid droplet accumulation in neuronal OH. support cells, and promotes neurodegeneration. Lucy Liu1, Ke Zhang2, Hector Sandoval3, Vafa Bayat4, Zhihong Li3, Shinya 562A Yamamoto3,4, Manish Jaiswal3, Richard Palmiter5,6, Albert Aneuploidy by Mitotic Spindle Defects Drives Tau-mediated Quintana5,6, Brett Graham3, Hugo Bellen6,7. 1) Department of Neurodegeneration in Drosophila. Bart Dermaut1, Marc Neuroscience, Baylor College of Medicine, Houston, TX; 2) Gistelinck2, Nicolas Malmanche1, Pierre Dourlen1, Cloé Dupont1, Structural and Computational Biology & Molecular Biophysics Dieder Moechars3, Patrick Callaerts2. 1) Institut Pasteur de Lille, Graduate Program, Baylor College of Medicine, Houston, TX; 3) Inserm U744, University of Lille 2, Lille, France; 2) Laboratory of Department of Molecular and Human Genetics, Baylor College of

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Medicine, Houston, TX; 4) Program in Developmental Biology, 580A Baylor College of Medicine, Houston, TX; 5) Department of A genetic screen for identifying novel genes involved in Biochemistry, University of Washington, Seattle, WA; 6) Howard neurodegeneration. Amy Pribadi, Shizuka Yamada, Megan Hughes Medical Institute; 7) Jan and Dan Duncan Neurological Huynh, Michael Chen, Ashley Boehringer, Daniela Zarnescu. Research Institute, Baylor College of Medicine, Houston, TX. University of Arizona, Tucson, AZ.

571A 581B Locating E-cadherin and Glial Cells in the Brain of the Drosophila The influence of mis-regulating dJNK in a Drosophila model of melanogaster During the Pupal Stage. Michael J. Lum. Vanguard Machado-Joseph Disease. Catherine Romberger, John Warrick. University of Southern California, Costa Mesa, CA. University of Richmond, Richmond, VA.

572B 582C Insights into Alzheimer’s disease from NMR metabolomics of Aβ- Uncovering Prion Protein Stability. Jonatan Sanchez-Garcia, expressing Drosophila. Anders Malmendal1, Stanislav Ott2, Diego Rincon-Limas, Pedro Fernandez-Funez. Univ of Florida, Damian Crowther2. 1) Department of Biomedical Science, Gainesville, FL. University of Copenhagen, Denmark; 2) Department of Genetics, University of Cambridge, United Kingdom. 583A Role of Signaling Pathways in Aβ42 mediated neurodegeneration. 573C Ankita Sarkar1, Amit Singh1,2,3. 1) Department of Biology, FoxO modulates neurotoxicity in a Drosophila model of ALS. University of Dayton, 300 College Park Drive,Dayton, OH; 2) Andrés A. Morera1, Daniela Zarnescu1,2,3. 1) Department of Premedical Program, University of Dayton, 300 College Park Molecular and Cell Biology, University of Arizona, Tucson, AZ; Drive, Dayton,OH; 3) Center for Tissue Regeneration and 2) Department of Neuroscience, University of Arizona, Tucson, Engineering at Dayton (TREND), University of Dayton, Dayton, AZ; 3) Department of Neurology, University of Arizona, Tucson, OH. AZ. 584B 574A Aggregate formation in the central nervous system of drosophila Structural and functional organization of a nucleus under stress in after a brief reduction in proteasome activity. Thomas Schmidt- Drosophila melanogaster: the role of the limk1 gene. Ekatherina Glenewinkel, Marlon Jansen, Chun-Hung Yeh, Annie Cheng, Jie Nikitina1,2, Anna Medvedeva1,3, Vladimir Pronikov2, Elena Gao, Eugene Lempert, Karina Perlaza. Dept Biological Sci, Hunter Savvateeva-Popova1,3. 1) Pavlov Institute of Physiology, St Col & Grad Ctr., City Univ New York, New York, NY. Petersburg, Russian Federation; 2) Herzen State Pedagogical University, St Petersburg, Russian Federation; 3) St Petersburg 585C State University, St Petersburg, Russian Federation. Probing integrin signaling in neuronal maintenance in flies. Mumine Senturk1, Shinya Yamamoto2, Manish Jaiswal3, Nele 575B Haelterman1, Hugo Bellen1,2,3,4. 1) Program in Developmental Mitochondrial abnormalities and nicotine treatment in a familial Biology, Baylor College of Medicine, Houston, TX; 2) Department model of Parkinson's disease. Morolake Odumosu1, Gerald Call2, of Molecular and Human Genetics, Baylor College of Medicine, Lori Buhlman1. 1) Biomedical Science, Midwestern University, Houston, TX; 3) HHMI; 4) Department of Neuroscience; Glendale, AZ; 2) Arizona College of Osteopathic Medicine, Neurological Research Institute at Baylor College of Medicine, Glendale, AZ. Houston, TX.

576C 586A Glial function of pak3 and draper show overlapping but distinct Nebula/DSCR1 Ameliorates APP-Induced Learning and Memory regulation of spastin neuronal synaptic bouton formation. Emily F. Impairments. Jillian L. Shaw, Karen T. Chang. Zilkha Ozdowski, Nina T. Sherwood. Dept Biol, Duke Univ, Durham, Neurogenetic Institute, University of Southern California, NC. Neuroscience Graduate Program. 587B 577A Investigating initiation of Cdk5-associated neurodegeneration. Using an Androgen Receptor-Humanized-Drosophila to Study the Joshua Spurrier1,2, Kristina McLinden1, Edward Giniger1. 1) Molecular Pathology of Spinal Bulbar Muscular Atrophy. Conor NINDS, National Institutes of Health, Bethesda, MD; 2) CMDB, Barker2, Stephanie Yee3, Paul Lasko3, Mark Trifiro1, Miltiadis Johns Hopkins University, Baltimore, MD. Paliouras1. 1) Medicine, Lady Davis Institute for Medical Research - Jewish General Hospital, Montreal, QC, Canada; 2) 588C Department of Cell Biology and Anatomy McGill University Role of Isocitrate Dehydrogenase in retinal degeneration in Montreal, QC, Canada; 3) Department of Biology McGill Drosophila melanogaster. Berrak A. Ugur1, Manish Jaiswal2,3, University Montreal, QC, Canada. Shinya Yamamoto2, Nele Haelterman1, Hector Sandoval2, Hugo Bellen1,2,3,4,5. 1) Developmental Biology, Baylor College of 578B Medicine, Houston, TX; 2) Department of Molecular and Human Implication of mutant Huntingtin protein (mHtt) in Huntington’s Genetics, Baylor College of Medicine, Houston, TX; 3) Howard disease pathogenesis in transgenic Drosophila. Nidhi Paliwal, Hughes Medical Institute; 4) Department of Neuroscience, Baylor Namita Agrawal. Department of Zoology, University of Delhi, College of Medicine, Houston, TX; 5) Jan and Dan Duncan Delhi, India. Neurological Institute at Baylor College of Medicine, Houston, Texas. 579C The Effects of Genetic Manipulation of Synaptotagmin 1 in a 589A Drosophila model of Machado-Joseph Disease. Rachel Pearcy, FoxO Mediates APP-Induced AICD-Dependent Cell Death. Lei John Warrick. University of Richmond, Richmond, VA. Xue, Xingjun Wang, Zhiqiang Wang. Tongji Univ, Shanghai, China.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

590B Investigation of the Role of Endoplasmic Reticulum in Motor 600C Neuron Axons. Belgin Yalcin, Niamh O'Sullivan, Martin pointed and vap Mediate Ethanol-Related Mortality in a Stofanko, Cahir O'Kane. Department of Genetics, University of Drosophila melanogaster Model of Fetal Alcohol Syndrome. Peter Cambridge, Cambridge, United Kingdom. Luu. biology, San Jose State University, San Jose, CA.

591C 601A A screen for RNA Binding Proteins as Modulators of TDP-43 Defining the phenotypic specificity of Schimke immuno-osseous toxicity in a Drosophila Model of ALS. Shizuka B. Yamada1, dysplasia. Marie Morimoto1, Clara Myung1, Kimberly Beirnes1, Amy Pribadi1, Megan Huynh1, Michael Chen1, Nakia Keita1, Linh Andrew Gormley2, Christy Mayfield3, Behzad Najafian4, David Pham1, Ashley Boehringer1, Daniela C. Zarnescu1,2. 1) MCB, Parham5, Zhongxin Yu6, Kunho Choi1, Yan Huang1, Kyoung Sang University of Arizona, Tucson, AZ; 2) Neuroscience, University of Cho7, Thomas Lücke8, Cornelius Boerkoel1. 1) Department of Arizona, Tucson, AZ. Medical Genetics, UBC, Vancouver, BC, Canada; 2) Department of Pediatrics, UOHSC, Oklahoma City, OK; 3) Warren Clinic, 592A Tulsa, OK; 4) Department of Pathology, UW, Seattle, WA; 5) Defining Spinal Muscular Atrophy Gene Networks in Drosophila. Department of Pathology, Children’s Hospital Los Angeles and Takakazu Yokokura1, Elizabeth McNeill2, Andreia Fonseca3, Keck School of Medicine, USC, Los Angeles, CA; 6) Department Maureen Lynes4, Seiko Yoshikawa1, Tamar Chobanyan1,2, Howard of Pathology, UOHSC, Oklahoma City, OK; 7) Department of Chang2, Douglas Dimlich2, Anindua Sen2, Spyros Artavanis- Biological Sciences, Konkuk University, Seoul, Republic of Tsakonas2, Lee Rubin4, Margarida Gama Carvalho3, David Van Korea; 8) Department of Neuropediatrics, University Children's Vactor1,2. 1) Okinawa Institute of Science and Technology, Hospital, Ruhr-University, Bochum, Germany. Okinawa, Japan; 2) Dept Cell Biology, Harvard Medical School, Boston, MA; 3) Bio-FIG, Faculty of Science, University of Lisbon, 602B Lisbon, Portugal; 4) Harvard University, Dept Stem Cell and Exposure of larvae to Perfluorooctanoic acid (PFOA) causes Regenerative Biology, Cambridge, MA. dysregulation of the dTOR signaling pathway in Drosophila melanogaster. AnnJosette Ramirez1, Edward Wolff2, Trisha 593B Zintel1, Amber Weiner1, Ashley Parker1, Kristin Johndreau1, Kara Proteomic Analysis of Huntingtin Interacting Network Using Bennett1, Caroline Rachfalski1, Sheryl T. Smith1. 1) Biology, Drosophila. Zhen Xu1,4, Dongsheng Chen1,4, Zhihua Chen1,4, Arcadia University, Glenside, PA; 2) Math and Computer Science, Yanning Rui1,4, Antonio Tito1,3,4, Sheng Zhang1,2,3,4. 1) Center for Arcadia University, Glenside, PA. Metabolic & Degenerative Diseases, The Brown Foundation Institute of Molecular Medicine; 2) Department of Neurobiology 603C and Anatomy; 3) The Graduate School of Biomedical Sciences Dube3a expression levels affect motor neuron axonal propagation (GSBS); 4) The University of Texas Health Science Center at and resting potential. Lawrence T. Reiter1,2, Colleen Valdez1, Houston (UTHEALTH), 1825 Pressler Street, Houston, TX 77030. Reese Scroggs2. 1) Neurology, UTHSC, Memphis, TN; 2) Anatomy and Neurobiology, UTHSC, Memphis, TN. 594C Transgenerational effect of diet on metabolic phenotypes. Kelly 604A Dew-Budd, Laura Reed. Department of Biological Sciences, Drosophila as a Simple Model to Test Dark Toxicity and Tolerance University of Alabama, Tuscaloosa, AL. of Potential Photodynamic Therapy Agents. Joshua Yoho1,4, Colette Stroh4, Shawn Swavey4, Madhuri Kango-Singh1,2,3. 1) 595A Biology, University of Dayton, Dayton, OH; 2) Center for Tissue Modulation of lipid droplet accumulation in the larval midgut of Regeneration and Engineering at Dayton (TREND); 3) Premedical Drosophila. Ron Dubreuil, Bianca Diaconeasa. Dept Biological Programs, University of Dayton, Dayton; 4) Chemistry, University Sci, Univ Illinois at Chicago, Chicago, IL. of Dayton, Dayton, OH.

596B 605B The Effects of Laminin A Mutation on Metabolic Syndrome in Role of miRNAs in Drosophila model for Muscular Dystrophy. Drosophila melanogaster. Matthew B. Kieffer, Joana Hubickey, Evgeniia V. Edeleva, April K. Marrone, Halyna R. Shcherbata. Laura K. Reed. University of Alabama, Tuscaloosa, AL. Max Planck Insitute for Biophysical Chemistry, Goettingen, Germany. 597C The influence of gene Cam on life span, moving activity and 606C Ca2+ concentration in dystrophy mutants of Drosophila Epigenetic regulation of lipase activity establishes a postnatal melanogaster.. Natalia Holub, Vasylyna Borutska, Chrystyna protection from high-fat diet induced obesity and heart Dronska, Yaroslava Chernyk. Departament of Genetics and dysfunction. Ryan Tyge Birse1, Fabian Filipp1,2, Rolf Bodmer1. 1) Biotechnology, Ivan Franko National University, Lviv, Ukraine. Program of Development and Aging, Sanford-Burnham Medical Research Institute, La Jolla, CA; 2) School of Natural Sciences, 598A University of California Merced, Merced, CA. A whole genome enhancer/suppressor screen for Dube3a interacting genes involved in autism. Addison E. Jezek1, 607A Lawrence T. Reiter2. 1) Rhodes College, Memphis, TN; 2) A Drosophila Model of Wolfram Syndrome Disease. Chan Hsiao- Department of Neurology, UTHSC, Memphis, TN. Yen1,2, Chen Yi-Chun1, Kuo Tzer-Min2, Lin Wan-Hsuan2, Li Jian- Chiuan2, Wang Horng-Dar1, Chen Chun-Hong2. 1) Institute of 599B Biotechnology, Department of Life Science, National Tsing Hua Modeling aberrant behavior of autism spectrum disorders in University, Hsinchu, Taiwan; 2) Institute of Molecular and UBE3A mutations. Matthew Lollar1, Rami Ajjuri1, Larry Reiter2, Genomic Medicine,National Health Research Institutes, Zhunan, Janis O'Donnell1. 1) Biological Sciences, University of Alabama, Miaoli, Taiwan. Tuscaloosa, AL; 2) Department of Neurology, University of Tennessee Health Science Center, Memphis, TN.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

608B Laboratory of Molecular Neurobiology, K.U. Leuven/VIB Center Analysis of transgenerational effects of Bisphenol A (BPA) in for the Biology of Disease, Leuven, Belgium; 2) Brainwave Ltd, Drosophila melanogaster. Ashley M. Labdik, Amber K. Weiner, University of Edinburgh, UK; 3) Laboratory of Behavioral and Trisha M. Zintel, AnnJosette Ramirez, Sheryl T. Smith. Arcadia Developmental Genetics, K.U. Leuven/VIB Center for the Biology University, Glenside, PA. of Disease, Leuven, Belgium.

609C 619A Effects of the Mediterranean Diet on Metabolic Phenotypes. dPKD2 trafficking in Drosophila sperm. Weizhe Li, Stacey Jordyn Lee Merriam, Laura Reed. Department of Biological Bridges, Terry Watnick. Department of Medicine, University of Sciences, University of Alabama, Tuscaloosa, AL. Maryland, Baltimore, MD.

610A 620B Cytoplasmic Protein Aggregation as a Trigger For LMNA Suppression of TOR pathway ameliorates skeletal muscle defects Associated Muscle Dystrophy. Jessica Ponce1, Dylan Thiemann2, in a Drosophila model of Huttingtons disease. Jennifer A. Suggs, Grant Young2, George Dialynas3, Lori Wallrath1,2. 1) Samvel Avagyan, Raul Ramos, Anju Melkani, Sanford I. Interdisciplinary Program in Genetics, University of Iowa, Iowa Bernstein, Girish C. Melkani. Department of Biology, Molecular City, IA; 2) Department of Biochemistry, University of Iowa, Iowa Biology and Heart Institutes, San Diego State University San City, IA; 3) Stowers Institute for Medical Research, Kansas City, Diego, CA 92182. MO. 621C 611B Modeling nerve injury in a long-lived Drosophila larval system. Genetic Basis of Genotype-by-Environment (GxE) Interactions for Daniel L. Miller, Barry Ganetzky. Department of Genetics weight in Drosophila melanogaster. A. Cigdem Tunckanat, Leah University of Wisconsin Madison 425 Henry Mall Madison, WI Leonard, Julie Jarnigan, Andrea Davidson, Laura Reed. 53706. Department of Biological Sciences, University of Alabama, Tuscaloosa, AL. 622A Behavioral models analogous to rodent depressive-like behaviors. 612C Wendi S. Neckameyer, Selma Avdagic, Andres Nieto, Kelly Drosophila Mitochondrial Pyruvate Carrier mutants display defects Hainz, Anisa Tabtiang, Sarah Chan. Dept Pharmac & Physiol Sci, in carbohydrate homeostasis and hallmarks of diabetes. Dona St Louis Univ School Med, St Louis, MO. Roonalika Wisidagama, Daniel K. Bricker, Carl S. Thummel. Department of Human Genetics, University of Utah, Salt Lake 623B city, UT. Effects of ethanol exposure on developmental time and survival in Drosophila. Victoria A. Pray1,2, Rachel A. Lyman1,2, Raveena M. 613A Chhabria2, Lenovia J. McCoy1, Tatiana V. Morozova1,2, Robert R. Oxidative stress as a consequence of ethanol exposure in H. Anholt1,2, Trudy F. C. Mackay1,2. 1) Biological Sciences, developing Drosophila. Anthony J. Bortolazzo, Jodie Wu, Naomi NCSU, Raleigh, NC; 2) W.M. Keck Center for Behavioral Fieger, David Do, Theresa Logan-Garbisch, Audrey Ford, Hilal Biology, NCSU, Raleigh, NC. Jarrar, Rachael French. Biological Sciences, San Jose State University , San Jose , CA. 624C Functional Modeling of Human Muscle Tauopathies in Drosophila. 614B Eric Ratliff2, Jennifer A. Suggs1, Kim D. Finley2, Sanford I. Rapamycin as a potential treatment for succinate dehydrogenase Bernstein1, Girish C. Melkani1. 1) Department of Biology, mutants in Drosophila melanogaster. Frances Fan, Eugenia Villa- Molecular Biology and Heart Institutes, San Diego State Cuesta. Biology Department, Adelphi University, Garden City, University San Diego, CA 92182; 2) Donald P. Shiley BioScience NY. Center, San Diego State University, San Diego, CA 92182.

615C 625A Determinants of Frailty in Drosophila. Mariann M. Gabrawy1,2, Expression of polyQ aggregates in non neuronal cells leads to Mehnaz A. Khan1, Peter M. Abadir2, Jeff Leips1. 1) Biological developmental anomalies in Drosophila melanogaster. Suman Sciences, UMBC, Baltimore, MD; 2) Division of Geriatric Yadav, Madhu G. Tapadia. CYTOGENETICS LABORATORY, Medicine, Johns Hopkins Medical Institute, Baltimore, MD. ZOOLOGY, BANARAS HINDU UNIVERSITY, VARANASI, 221005, UTTAR PRADESH, India. 616A Mutations in von Hippel Lindau Enhances Susceptibility to

Paraquat and Exarcebates Neuroinflammatory and Hypoxia Responses. Marleshia Dorcell Hall, Anna Moyer, Erin Mcminn, Evolution and Quantitative Genetics Emily Peel, Janis O'Donnell. Department of Biological Sciences, University of Alabama, Tuscaloosa, AL. 626B 617B Multiple DNA motifs contribute to variation in recombination Nephrocyte as a model to identify and study renal disease genes. 1,2 1 1 1 1 localization across the Drosophila genome. Andrew Adrian , Fujian Zhang , Tiffany Chang , Ying Zhao , Katherine Muir , Zhe 1,3 1,2 Josep Comeron . 1) Department of Biology, University of Iowa, Han . 1) Internal Med, Univ Michigan, Ann Arbor, MI; 2) Iowa City, IA; 2) Interdisciplinary Program in Bioinformatics, Sanford Burnham Medical Research Institute, La Jolla, CA. University of Iowa; 3) Interdisciplinary Program in Genetics, University of Iowa. 618C CYFIP1 functions in brain: insights into Autism and Intellectual Disabilities. Alexandros Kanellopoulos1, Lysimachos Zografos2, Douglas Armstrong2, Patrick Callaerts3, Claudia Bagni1. 1)

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

627C 637A Nucleotide Polymorfism of Enhancer Region of DRAS1 Gene in Evolution of Germline Stem Cell Regulating Genes in Drosophila The Drosophila Virilis Sibling Species Group. Sivoplyas ananassae: Testing the Wolbachia pipientis conflict hypothesis. Ekaterina2, Chekunova Anna1, Proshakov Prokhor1, Barsukov Jae Young Choi, Charles Aquadro. Dept of Molecular Biology Maxim2, Sorokina Svetlana1, Mitrofanov Vladimir1, Kutuzova and Genetics, Cornell University, Ithaca, NY. Nina2. 1) Russian Academy of Sciences Koltzov Institute of Developmental Biology; 2) FSFEI of HPE Moscow State 638B Pedagogical University (MSPU). Life History Determinants: Physiological Mechanisms of Egg Dumping in Drosophila melanogaster Using Extreme Phenotypes 628A and Genetic Mapping. Ashley A. Gilchrist1, Laura Reed2, Trish Muller F elements maintain a distinctive pattern of gene structure Moore3. 1) Ashley Gilchrist Biological Sciences, University of over 40 million years of evolution. Wilson Leung1, Christopher Alabama, Tuscaloosa, AL; 2) Laura Reed PhD, Dept. Biology, Shaffer1, Jeremy Buhler2, Sarah Elgin1, Faculty & Students of the UA; 3) Trish Moore PhD, Department of Entomology, University Genomics Education Partnership. 1) Dept Biology, Washington of Georgia. Univ, St Louis, MO; 2) Dept Computer Science & Engineering, Washington Univ, St. Louis, MO. 639C Differences in regulatory variability between sexes and ’X’s, in D. 629B simulans. Rita M. Graze1,6, Lauren M. McIntyre1,2, Alison M. Genome-wide effect of 785 generations of parallel adaptation in Morse1, Brett M. Boyd5, Sergey V. Nuzhdin3, Marta L. Wayne4. 1) replicate populations of Drosophila melanogaster. Mark A. Department of Molecular Genetics and Microbiology, University Phillips1, Anthony D. Long1,2, Lee F. Greer1,2, Laurance D. of Florida, Gainesville, FL; 2) Department of Statistics, University Mueller1,2, Michael R. Rose1. 1) Ecology and Evolutionary of Florida, Gainesville, FL; 3) Section of Molecular and Biology, University of California, Irvine, CA; 2) Genescient Computational Biology, Department of Biological Sciences, Corporation, Fountain Valley, CA 92708. University of Southern California, Los Angeles, CA; 4) Department of Biology, University of Florida, Gainesville, FL; 5) 630C Florida Museum of Natural History, University of Florida, Domesticated genes from PIF transposable elements in Drosophila Gainesville, FL; 6) Biological Sciences, Auburn University, melanogaster. Diwash Jangam1, Cedric Feschotte2, Esther Auburn, AL. Betrán1. 1) Biology, University of Texas at Arlington, Arlington, TX; 2) Human Genetics, University of Utah, Salt Lake City, UT. 640A Whole genome sequencing of Drosophila melanogaster from the 631A southeast United States and Caribbean Islands to investigate Genome of Scaptomyza flava, a leaf mining drosophilid. Richard admixture in North America. Joyce Y. Kao, Matt P. Salomon, Asif Lapoint, Noah Whiteman. Dept of Ecology and Evolutionary Zubair, Daniel Campo. Biological Sciences, University of Biology, University of Arizona, Tucson, AZ. Southern California, Los Angeles, CA.

632B 641B Regulatory impacts of tandem duplications in Drosophila yakuba. The genetic basis of high-altitude adaptation in Drosophila Rebekah L. Rogers, Ling Shao, Kevin Thornton. Ecology and melanogaster. Justin B. Lack, John Pool. Laboratory of Genetics, Evolutionary Biology, Thornton Lab, Irvine, CA. University of Wisconsin-Madison, Madison, WI.

633C 642C A Novel Dataset for Identifying Sex-Biased Genes in Drosophila. Clinal patterns of genomic variation and their demographic Nicholas VanKuren1,2, Maria Vibranovski2,3. 1) Committee on implications in D. melanogaster and D. simulans. Heather Genetics, Genomics, and Systems Biology, The University of Machado1, Alan Bergland1, Katherine O'Brien2, Emily Behrman2, Chicago, Chicago, IL, USA; 2) Department of Ecology and Paul Schmidt2, Dmitri Petrov1. 1) Biology, Stanford University, Evolution, The University of Chicago, Chicago, IL, USA; 3) Palo Alto, CA; 2) Department of Biology, University of Departamento de Genética e Biologia Evolutiva, Instituto de Pennsylvania, Philadelphia, PA. Biociências, Universidade de São Paulo, São Paulo, Brazil. 643A 634A Recent colonization history of the invasive drosophilid Zaprionus Drosophila simulans wRi Wolbachia variants differ by multi-gene indianus in Mexico and Central America. Therese Ann Markow1,2, duplications in a natural population. Chenling Xu, Chris Smith. Giovanni Hanna2, Juan R. Riesgo-Escovar3, Maxi Polihronakis Evolution and Ecology, UC Davis, Davis, CA. Richmond2, Nestor Octavio Nazario-Yepiz1, Mariana Ramírez- Loustalot-Laclette1, Javier Carpinteyro-Ponce1, Edward Pfeiler4. 1) 635B Laboratorio Nacional de Genómica para la Biodiversidad, Directional asymmetry of the Drosophila wing as a target of CINVESTAV Irapuato, Irapuato, Guanajuato, C.P. 36821 Mexico; evolution of bilateral traits. Denis Anisiforov, Alexey Kulikov, 2) Division of Biological Sciences, University of California, San Oleg Lasebny. Russian Academy of Sciences, Koltzov Diego, La Jolla, CA 92093, USA; 3) Departamento de INSTITUTE of DEVELOPMENTAL BIOLOGY , Moscow, Neurobiología del Desarrollo y Neurofisiología, Instituto de Russian Federation. Neurobiología, Universidad Nacional Autónoma de México, Querétaro, C.P. 76230, México; 4) Centro de Investigación en 636C Alimentación y Desarrollo, A.C., Unidad Guaymas, Apartado Genomic basis of parallel evolution of dark pigmentation in high- Postal 284, Guaymas, Sonora, 85480, México. altitude populations of Drosophila melanogaster in Africa. Héloïse Bastide, Amir Yassin, Justin Lack, Evan Johanning, John Pool. 644B Laboratory of Genetics, University of Wisconsin-Madison, Identifying functional elements and species-specific gain and loss Madison, WI. of function from population genomic data. Daniel R. Schrider, Andrew D. Kern. Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

645C 655A “Molecular fossils” and genetic diversity of ancestral population of Study of function of two young nuclear transport retrogenes (Dntf- D.virilis. Svetlana Y. Sorokina1, Sergej V. Bukhanov1, Denis A. 2r and Ran-like). Susana Domingues, Erica Eckstrand, Esther Romanov2, Boris V. Andrianov2. 1) Genetics, Koltzov Betrán. The University of Texas at Arlington, Arlington, TX. INSTITUTE of DEVELOPMENTAL BIOLOGY RAS, Moscow, Russian Federation; 2) Vavilov INSTITUTE of GENERAL 656B GENETICS RAS, Moscow, Russian Federation. Molecular evolution of the proteins comprising the synaptonemal complex in the Drosophila genus. Lucas Hemmer, Justin 646A Blumenstiel. Ecology and Evolutionary Biology, Univ of Kansas. Regulation of developmental timing in the Drosophila embryo. Cynthia Staber, Axel Shum, Samuel Meier, Julia Zeitlinger. 657C Stowers Institute for Medical Research, Kansas City, MO. The insect order Diptera as framework to assess the genetics of morphological divergence. Steffen Lemke, Silvia Urbansky, 647B Francesca Caroti, Lucas Schütz. Centre for Organismal Studies, Latitudinal variation in sleep in Drosophila melanogaster. Nicolas Universität Heidelberg, Heidelberg, Germany. Svetec1, Perot Saelao1, Joanna Chiu2, David Begun1. 1) Department of Evolution & Ecology, UC Davis, Davis, CA; 2) 658A Department of Entomology and Nematology, UC Davis, CA. Evolution of the maternally deposited mRNA pool in the Drosophila egg. Susan E. Lott. Department of Evolution and 648C Ecology, University of California, Davis, Davis, CA. What gene expression can tell us about selective forces driving chromosome evolution. Gwilym Haynes1, Zachary Fuller1, 659B Shannon Duggan2, Stephen Richards2,3, Stephen Schaeffer1. 1) Evolution of shape and sense in male Drosophila prolongata. Biology, Pennsylvania State University, State College, PA; 2) David Luecke, Artyom Kopp. Center for Population Biology, Human Genome Sequencing Center, Baylor College of Medicine, University of California - Davis, Davis, CA. One Baylor Plaza, Houston TX 77030; 3) Chevron, Houston, TX. 660C 649A Coordinated cis- and trans-regulatory changes along the dpp DNA copy number evolution in Drosophila modENCODE cell pathway correlate with a derived wing phenotype in D. sechellia. lines. Hangnoh Lee, Brian Oliver, modENCODE. National Richard W. Lusk1, Nuala Bobowski2, Alberto Civetta2, Cassandra Institute of Diabetes, Digestive, and Kidney Diseases, National Kirkland1, Emily Valice1, Patricia Wittkopp1, Ian Dworkin3. 1) Institutes of Health, Bethesda, MD. Ecology & Evolutionary Biology, University of Michigan, Ann Arbor, MI; 2) Dept. of Biology, University of Winnipeg, 650B Winnipeg, MB, Canada; 3) Dept. of Zoology, Michigan State The Evolution of Breakpoint Sequences in Drosophila University, East Lansing, MI. pseudoobscura. Haley E. Randolph1, Megan E. Lee1, Geovanny C. Montoya1, Atousa Jahanshahi1, Shannon Duggan2, Dianhuiz 661A Zhu2,3, Stephen Richards2, Stephen W. Schaeffer1. 1) Biology, The Conservation of long intergenic noncoding RNAs (lincRNAs) Pennsylvania State University, University Park, PA; 2) Human between D. pseudoobscura and D. melanogaster: expression is key. Genome Sequencing Center, Baylor College of Medicine, One Kevin G. Nyberg, Carlos A. Machado. Biology Department, Baylor Plaza, Houston TX; 3) Chevron, 1500 Louisiana St, University of Maryland, College Park, MD. Houston, Texas. 662B 651C Molecular mechanism behind the evolution of a novel sex-specific The ovipositor of an invasive pest, Drosophila suzukii, provides trait. Gavin R. Rice1, Olga Barmina1, Michelle Arbeitman2, Daniel insight into the evolution of an adaptive novelty. Joel Atallah, Friedman1, Artyom Kopp1. 1) Evolution and Ecology, University Raul Salazar, Lisa Teixeira, George Zaragoza, Artyom Kopp. of California at Davis, Davis, CA; 2) College of Medicine, Florida Evolution & Ecology, University of California - Davis, Davis, CA. State University, Tallahassee, FL.

652A 663C Microsatellite repeat instability fuels evolution of embryonic What does it take to evolve an enhancer? Saurabh Sinha1,2, enhancers in Hawaiian Drosophila. Andrew S. Brittain, Elizabeth Thyago S. P. C. Duque1. 1) Department of Computer Science, Stroebele, Albert Erives. University of Iowa, Dept. of Biology, University of Illinois, Urbana, IL; 2) Institute for Genomic Iowa City, IA 52242, USA. Biology, University of Illinois, Urbana, IL.

653B 664A Dorsocross is a putative target for morphological divergence in fly Gene expression profiling of Drosophila testis. Toshiyuki embryos. Francesca Caroti, Steffen Lemke. Molecular Takano-Shimizu, Masatoshi Tomaru, Masahide Watanabe. Developmental Biology & Physiology, Center for Organismal Drosophila Genetic Resource Center, Kyoto Institute of Studies (COS), Heidelberg, Baden-Württemberg, Germany. Technology, Kyoto.

654C 665B Genome of Drosophila arizonae and its divergence from D. Comparative transcriptomics of X chromosome meiotic drive in mojavensis. Javier Carpinteyro Ponce1, Fernando Peñaloza2, Drosophila simulans. Shu Fang1, Wei-Chung Yu1, David Alejandro Sanchez2, Cei Abreu-Goodger1, Therese Markow1,3. 1) Ogereau2, Ching-Ho Chang3, Quentin Helleu2, Chau-Ti Ting3, LANGEBIO, CINVESTAV Irapuato, Irapuato, Guanajuato, Catherine Montchamp-Moreau2. 1) Biodiversity Research Center, Mexico; 2) Unidad Universitaria de Apoyo Bioinformático, Academia Sinica, Taiwan, ROC; 2) Laboratoire Evolution, Instituto de Biotecnología, UNAM, Cuernavaca, Morelos. México; Génomes & Spéciation, UPR9034 - CNRS, France; 3) Department 3) Division of Biological Sciences, UCSD, La Jolla, CA. of Life Science, Natl Taiwan University, Taipei, Taiwan, ROC.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

666C Study of segmentation using Dermestes maculatus as a non-model 677B organism. Jie Xiang1,2, Leslie Pick1,2. 1) Dept of Entomology, The genetics of convergent evolution. Sarah A. Signor1, Artyom Univ. of Maryland-College Park, College Park, MD; 2) Program in Kopp2. 1) University of Southern California, Los Angeles, CA; 2) Molecular & Cell Biology, Univ. of Maryland-College Park. University of California, Davis, Davis, CA.

667A 678C How does selection at tyrosine hydroxylase (pale) drive melanism Divergence of water balance mechanisms in two sibling species in high-altitude Ethiopian Drosophila melanogaster? Amir (Drosophila simulans and D. melanogaster ): effects of growth Yassin, Héloïse Bastide, John Pool. Laboratory of Genetics, temperatures. Divya Singh, Ravi Parkash. M.D.UNIVERSITY, University of Wisconsin-Madison, Madison, WI. ROHTAK, HARYANA, India.

668B 679A QTL affecting genotype-by-diet interactions of larval triglyceride Mapping natural variation in courtship song to the gene level using levels. Alison F. Adams, Kelly J. Dew-Budd, Laura K. Reed. the Drosophila Synthetic Population Resource. Thomas L. Department of Biological Sciences, The University of Alabama, Turner, Alison Pischedda, Wes G. Cochrane, Veronica A. Tuscaloosa, AL. Cochrane. Ecology Evolution and Marine Biology Dept, University of California, Santa Barbara. 669C Genomic basis of parallel seasonal variation in stress tolerance 680B traits in Drosophila melanogaster and D. simulans. Alan O. Reproductive barriers in a hybrid zone of Drosophila Bergland1, David Enard1, Felicia King1, Jamilla Akhund-Zade1,2, melanogaster. Joyce Y. Kao, Sergey V. Nuzhdin. Biological Dmitri Petrov1. 1) Stanford University, Stanford, CA; 2) Cornell Sciences, University of Southern California, Los Angeles, CA. University, Ithica, NY. 681C 670A Investigating genomic divergence in the Asian fruit fly Drosophila Climatic adaptations of life-history traits in outdoor field cage and nasuta complex. Wynn K. Meyer, Doris Bachtrog. Integrative laboratory populations of Drosophila melanogaster. Veer Bhan. Biology, University of California, Berkeley, Berkeley, CA. Department of Biotechnology, UIET, M D University, Rohtak, Haryana, India. 682A Genome-wide scans reveal a young candidate speciation gene in 671B Drosophila athabasca. Karen M. Wong Miller1, Michael Naturally Occurring Variations in Food Intake in Drosophila Eisen1,2,3, Doris Bachtrog1. 1) Integrative Biology, University of melanogaster. Matthew John Eveland, Hayley Leuch, Maria De California, Berkeley, Berkeley, CA; 2) Department of Molecular Luca. Nutrition Sciences, University of Alabama, Birmingham, and Cell Biology, University of California, Berkeley, CA; 3) Birmingham, AL. Howard Hughes Medical Institute, University of California, Berkeley, CA. 672C Bayesian multi-phenotype genome-wide association methods for 683B experimental designs of arbitrary complexity. Anthony The role of fungal interactions in the host-plant specialization of Greenberg1,2, Jason Mezey1, Susan McCouch1,2, Jean-Luc Hawaiian Drosophila. Allison Quan1, Patrick O'Grady2, Michael Yannink3. 1) Biostatistics and Computational Biology, Cornell Eisen1. 1) Department of Molecular and Cell Biology, UC University, Ithaca, NY; 2) Plant Breeding and Genetics, Cornell Berkeley, Berkeley, CA; 2) Department of Environmental Science, University, Ithaca, NY; 3) USDA-ARS, Robert W. Holley Center, Policy & Management, UC Berkeley, Berkeley, CA. Ithaca, NY. 684C 673A Radiation of the Drosophila nannoptera species group in Mexico. The relationship between sleep and evolutionary fitness in Michael Lang1, Maxi Polihronakis Richmond2, Andrea E. Drosophila melanogaster . Amanda Lobell, Susan Harbison. Acurio3, Therese A. Markow2,4, Virginie Orgogozo1. 1) CNRS Laboratory of Systems Genetics, Division of Intramural Research, UMR7592, Institut Jacques Monod, Paris, France; 2) University of National Heart, Lung and Blood Institute, Bethesda, MD. California, San Diego, USA; 3) Universitat Autònoma de Barcelona, Barcelona, Spain; 4) Laboratorio Nacional de 674B Genomica de la Biodiversidad, CINVESTAV, Irapuato, Mexico. What is the best design to understand gene regulatory networks? Lauren M. McIntyre1, Sergey Nuzhdin2. 1) Dept Molec Gen & 685A Micro, Univ Florida, Gainesville, FL; 2) University of Southern Bioinformatic Analysis of Odorant-Binding Proteins from an California, Los Angeles CA. Emerging Agricultural Pest, Drosophila suzukii. Herbert Lee, Jessica Wu-Woods, Daniel Woods. Inscent, Inc., Irvine, CA. 675C Mapping divergent pupation behavior between Drosophila 686B melanogaster and D. simulans. Alison Pischedda, Michael The transposable element Bari-Jheh mediates oxidative stress Shahandeh, Thomas Turner. Department of Ecology, Evolution response in Drosophila. Josefa Gonzalez, Lain Guio, Lidia Mateo, and Marine Biology, University of California, Santa Barbara, Anna Ullastres, Maite Barron. Institute of Evolutionary Biology, Santa Barbara, CA. Barcelona, Barcelona, Spain.

676A Genes of Attraction: Mapping male preference for a species- specific female pheromone in Drosophila. Michael Shahandeh, Alison Pischedda, Thomas Turner. Ecology, Evolution and Marine Biology, University of California, Santa Barbara, CA.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

687C Genome-wide analysis of positive selection in an herbivorous 698B drosophilid. Andrew Gloss, Richard Lapoint, Noah Whiteman. Pathogen pressures increase the rate of meiotic recombination in University of Arizona, Tucson, AZ. Drosophila. Dallas Criscoe1, Erin Keebaugh2, Shelly Skolfield2, Todd Schlenke2, Nadia Singh1. 1) Department of Biological 688A Sciences, North Carolina State University, Raleigh, NC; 2) Soft shoulders ahead: on the problem of differentiating between Department of Biology, Emory University, Atlanta, GA. hard and soft sweeps. Andrew D. Kern1, Daniel R. Schrider1, Fabio Mendes2, Matthew Hahn2. 1) Dept of Genetics, Rutgers 699C University, Piscataway, NJ; 2) Dept of Biology, Indiana Sexual dimorphism in extent and mechanisms of resistance to University, Bloomington, IN. infections shows that the Bateman principle does not apply to Drosophila immunity. David Duneau, Brian Lazzaro. 689B Entomology, Cornell University, Ithaca, NY. Transmission of mitochondrial mutations and action of purifying selection in Drosophila. Hansong Ma1, Hong Xu2, Patrick 700A O'Farrell1. 1) Department of Biochemistry & Biophysics, UCSF, Divergence of desiccation-related traits in two Drosophila species San Francisco, CA; 2) National Heart, Lung, and Blood Institute, of the takahashii subgroup from the western Himalayas. Babita Molecular Genetics Lab, Bethesda, MD 20892. Kajla, Ravi Parkash. Department of Genetics, M. D.UNIVERSITY, ROHTAK, Haryana, India. 690C Direct and correlated responses to laboratory selection for body 701B melanisation in Drosophila melanogaster: support for the Divergence of water balance mechanisms and acclimation melanisation-desiccation resistance hypothesis. Seema Ramniwas, potential in body color morphs of a tropical rainforest Drosophila Ravi Parkash. GENETICS, M. D.UNIVERSITY, ROHTAK, India. species. Chanderkala Lambhod, Ravi Parkash. M.D.UNIVERSITY, ROHTAK, haryana, India. 691A The effect of linked selection on Approximate Bayesian estimation 702C of demographic parameters. Alexander G. Shanku, Andrew D. Seasonal changes in humidity impact drought resistance in tropical Kern. Department of Genetics, Rutgers University, Piscataway, NJ. Drosophila leontia: testing developmental effects of thermal versus humidity changes. Poonam Ranga, Ravi Parkash. GENETICS, 692B MAHARSHI DAYANAND UNIVERSITY, ROHTAK, India. The contributions of epistasis and biochemical plasticity to ethanol tolerance across life stages. Brandon S. Cooper, P. Signe White, 703A Kristi L. Montooth. Biology, Indiana University, Bloomington, IN. MiRNA transcriptome follows different evolutionary trajectories at the onset of Drosophila metamorphosis. Shu-Dan Yeh1, Marcin 693C von Grotthuss1, Vivek Jayaswal2, José Ranz1. 1) Ecology and Understanding the influence of diet and gut microflora on host Evolutionary Biology, UC Irvine, Irvine, CA; 2) School of behavior and mate preferences in Drosophila melanogaster. Mathematics and Statistics, The University of Sydney, Sydney, Michael A. Najarro, Thomas L. Turner. Dept. of Ecology, Australia. Evolution, and Marine Biology, University California Santa Barbara, Santa Barbara, CA.

694A Pattern Formation Genetic and plastic effects on body melanisation in a cold adapted drosophilid -Drosophila takahashii. Shama Singh. ZOOLOGY, UNIVERSITY OF DELHI, DELHI, India. 704B Novel Interactions between the NF-κB and BMP Signaling 695B Pathways in the D. melanogaster Embryo. Sophia Carrell, Mitonuclear epistasis and the transcriptional response to hypoxia. Alexander Thomas, Jeramey Friedman, Gregory Reeves. Chemical David M. Rand, Yawei Ge, Nicholas Jourjine, James Mossman. and Biomolecular Engineering, North Carolina State University, Ecology & Evolutionary Biol, Brown Univ, Providence, RI. Raleigh, NC.

696C 705C Yeast metabolic state mediates attraction of wild Drosophila 1 Differential cell response to Epidermal Growth Factor Receptor melanogaster to suitable breeding sites. Kelly M. Schiabor , 1 1,2 (EGFR) signalling in the ovary. Scott De Vito , Jean François Michael B. Eisen . 1) Molecular and Cell Biology, University of Boisclair Lachance2, Mariana Fregoso Lomas1, Laura Nilson1. 1) California, Berkeley, Berkeley, CA; 2) Howard Hughes Medical Deparment of Biology, McGill University, Montreal, QC, Canada; Institute, Bethesda, MD. 2) Ben May Department for Cancer Research, University of Chicago, Chicago, Il. 697A Robust genome-wide analysis of metabolic phenotypes in 706A Drosophila melanogaster using a panel of hybrid genotypes 1 A role for ABCF2 in early morphogenetic patterning. Rachel containing a common haplotype. Kjong-Van Lehmann , Peter 1 2 3 1 2 2 2 2 Harney , Byron Williams , Mike Hayes , Arida Dhanaswar , Poon , Daniel Campo , Matthew Salomon , Peter Chang , Tevik 1 1 4 4 2 3 3 4 Danielle Beekman , Clinton Rice , Karla Daniels , David Soll , Hamdi Kitapci , Justin Fear , Alison Morse , Michelle Arbeitman , 3 1 1 3 5 2 2 Daniel Weeks , Jan Fassler , Albert Erives . 1) Dept. of Biology, Lauren McIntyre , Simon Tavare , Sergey Nuzhdin , John Tower . University of Iowa, Iowa City, IA; 2) Interdisciplinary Program in 1) Memorial Sloan Kettering Cancer, New York, NY; 2) Genetics, University of Iowa, Iowa City, IA; 3) Dept. of University of Southern California, Los Angeles, CA; 3) University Biochemistry, University of Iowa, Iowa City, IA; 4) of Florida, Gainesville, FL; 4) Florida State University, Developmental Studies Hybridoma Bank, University of Iowa, Tallahassee, FL; 5) Cancer Research, Cambridge, UK. Iowa City, IA.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

707B 717C Self-organized shuttling: generating sharp dosro-ventral polarity in Cytoneme-mediated Notch signaling between wing disc myoblasts the early Drosophila embryo. Michal Haskel-Ittah, Danny Ben- and trachea. Hai Huang, Sougata Roy, Thomas Kornberg. Zvi, Merav Branski-Arieli, Eyal Schejter, Naama Barkai, Benny Cardiovascular Research Institute, UCSF, San Francisco, CA. Shilo. molecular genetics, weizmann institute, Rehovot, Israel. 718A 708C Dual role for Dpp in early wing disc development in regulating Maternal Torso-like functions post terminal patterning to control EGFR and Wg signaling. Sathiya Narayanan Manivannan1, Drosophila gastrulation. Travis K. Johnson1,2, James C. Amanda Simcox1,2. 1) Molecular Cellular Developmental Biology, Whisstock1, Coral G. Warr2. 1) Biochemistry and Molecular The Ohio State University, Columbus, OH; 2) The Department of Biology, Monash University, Clayton, Victoria, Australia; 2) Molecular Genetics, The Ohio State University, Columbus, OH. School of Biological Sciences, Monash University, Clayton, Victoria, Australia. 719B Pan-leg developmental regulators control pro-thoracic leg specific 709A Scr expression. Christopher L. McCallough, Ece Eksi, Emily R. Role of BMP signaling in serosa and amnion development of the Wyskiel, Teresa V. Orenic. Dept Biological Sci, Univ Illinois at phorid fly Megaselia abdita. Chun Wai Kwan, Urs Schmidt-Ott. Chicago, Chicago, IL. Dept. of Organismal Biology and Anatomy, Univ of Chicago. 720C 710B Modeling dorsoventral patterning of the Drosophila embryo in The Regulation of Dorsoventral Patterning in the Early Drosophila silico reveals critical details overlooked by fluorescence imaging Embryo. Ruta Ziukaite. New York University, New York, NY. studies. Michael D. O'Connell, Gregory T. Reeves. Chemical & Biomolecular Engineering, North Carolina State University, 711C Raleigh, NC. Compartments in the second tracheal metamere of Drosophila larva. Prashanth Rao, Li Lin, Sougata Roy, Thomas Kornberg. 721A CVRI, UCSF, San Francisco, CA. Lethal (2) Essential for Life Gene Regulates Lateral Muscle Shapes During Embryonic Development. Teresa Jagla, Inga 712A Wojtowicz, Krzysztof Jagla. GReD, INSERM U1103, CNRS The Drosophila T-box Transcription Factor Midline Functions UMR6293, Clermont, FD, France. within the Notch-Delta Signaling Pathway to Specify Sensory Organ Precursor Cell Fates and Regulates Cell Survival within the 722B Eye Imaginal Disc. Sandra M. Leal, Sudeshna Das, Qichuan Gene regulatory domains controlling eggshell patterning are Chen, Joseph Saucier, Brandon Drescher, Sarah Morgan, John enriched within the first intron. Nicole Pope1, Maira Farhat2, Forstall, Andrew Meriwether, Randy Toranzo. Dept Biological Robert Marmion1, Nir Yakoby1,2. 1) CCIB Rutgers University- Sci, Univ Southern Mississippi, Hattiesburg, MS. Camden, Camden, NJ; 2) Biology Rutgers University-Camden, Camden, NJ. 713B defective proventriculus (dve), a new member of DV patterning in the eye. Oorvashi Roy G. Puli1, Takeshi Yorimitsu3, Madhuri Kango-Singh1,2,4, Hideki Nakagoshi3, Amit Singh1,2,4. 1) Regulation of Gene Expression Department of Biology, University of Dayton, 300 College Park Drive, Dayton, OH; 2) Premedical Program, University of Dayton, 300 College Park Drive, Dayton, OH; 3) School of Natural Science 723C and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita- The tfiia-s-2 gene is a germline-specific homolog of the small ku, Okayama 700-8530, Japan; 4) Center for Tissue Regeneration subunit of the General Transcription Factor TFIIA. Maura and Engineering at Dayton (TREND), University of Dayton, Coughlin, Kevin Wons, Leah Hirschman, Cynthia Cain, Mark Dayton, OH. Hiller. Biological Sciences, Goucher College, Baltimore, MD.

714C 724A Role of growth regulatory pathway in eye development and Identification of phosphorylation sites of the transcription factor differentiation. Erika L. Wittkorn1, Kristine Garcia1, Madhuri 1,2,3 1,2,3 MEF2 in vivo. Ashley A. DeAguero, Melanie Adams, Marilyn Kango-Singh , Amit Singh . 1) Department of Biology, Cisneros, Richard M. Cripps. Biology, University of New Mexico, University of Dayton, 300 College Park Drive, Dayton, OH; 2) Albuquerque, NM. Premedical Program, University of Dayton, 300 College Park Drive, Dayton, OH; 3) Center for Tissue Regeneration and 725B Engineering at Dayton (TREND), University of Dayton, Dayton, Determining general and male-specific functions of the essential OH. protein CLAMP in Drosophila Melanogaster. Jennifer Johnson, Erica Larschan. Brown University, Providence, RI. 715A A genetic screen in wing imaginal discs for regeneration mutants. 726C Amanda R. Brock, Rachel K. Smith-Bolton. Cell and Regulation of a conserved Class I/ Class V Helix-Loop-Helix Developmental Biology, University of Illinois at Urbana- (HLH) Gene Regulatory Network. Ke Li, Nicholas Baker. Champaign, Urbana, IL. Genetics, Albert Einstein College of Medicine, Bronx, NY.

716B 727A Evolution of dipteran wing vein patterning. Valentino M. Gantz, The molecular basis of enhancer-promoter choice. Jia Ling, Xiang-Ru Xu, Ethan Bier. Biological Sciences, University of Theresa Apoznanski, Jinshuai Cao, Stephen Small. Department of California San Diego, La Jolla, CA. Biology, New York University, New York, NY.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

738C 728B Novel Gli-independent regulation of Hedgehog target enhancers KDM5 interacts with Foxo to modulate cellular levels of oxidative via Gli binding sites. Andrea Isabel Ramos1, Scott Barolo1,2. 1) stress. Xingyin Liu, Christina Greer, Julie Secombe. Genetics, Program in Cellular and Molecular Biology,; 2) Department of Albert Einstein Med College, Bronx, NY. Cell and Developmental Biology, University of Michigan, Ann Arbor, MI. 729C Genome-wide analysis of tissue-specific effector genes in the 739A Drosophila embryo. Malini Natarajan, Samuel Meier, Jeff Identification of novel STAT92E target genes in hematopoiesis Johnston, Julia Zeitlinger. Stowers Institute for Medical Research, using in silico methods. Aditi Vyas1, Rami Al-Ouran2, Lonnie Kansas City, MO. Welch2, Soichi Tanda1. 1) Dept. of Biological Sciences, Ohio University, Athens, OH; 2) School of Electrical Engineering and 730A Computer Science, Ohio University, Athens, OH. Identification of New Wingless Targets in Drosophila via ChIP- seq. Claudia Rockel, Konrad Basler. University of Zürich, Zürich, 740B Switzerland. The Mechanistic Basis for the Conservation of Enhancer Grammar Elements. Jenny E. Atanasov, James W. Posakony. Division of 731B Biological Sciences-CDB, UCSD, La Jolla, CA. Differential utilization of TATA Box-Binding Protein (TBP) and TBP-related Factor 1 (TRF1) at different classes of RNA 741C polymerase III promoters. Neha Verma1, Ko-Hsuan Hung2, Jin The Effects of Poly-Glutamine Tract Variation on Protein-Protein Joo Kang2, William Stumph2. 1) Dept. of Biology, San Diego State Interactions in Enhanceosomes. Danielle Beekman, Clinton Rice, University, San Diego, CA 92182; 2) Dept. of Chemistry and Megan Bowman, Rachel Harney, Albert Erives. Dept. of Biology, Biochemistry, San Diego State University, San Diego, CA 92182. University of Iowa, Iowa City, IA, 52242, USA.

732C 742A Measuring polymerase dynamics with multi-color fluorescent in Non-additive cis-regulatory interactions underlie pair-rule situ hybridization. Shawn C. Little1, Mikhail Tikhonov2, Eric F. regulation of Drosophila wingless at the blastoderm stage. Wieschaus1, Thomas Gregor2. 1) Department of Molecular Biology Kimberly Bell1,2, Kevin Chen1, Jinelle Wint1,3, J. Peter Gergen1. 1) / HHMI, Princeton University, Princeton, NJ; 2) Joseph Henry Department of Biochemistry and Cell Biology and the Center for Laboratories of Physics / Lewis-Sigler Institute for Integrative Developmental Genetics, Stony Brook University, Stony Brook, Genomics, Princeton University, Princeton, NJ. NY; 2) Graduate Program in Genetics, Stony Brook University, Stony Brook, NY; 3) Graduate Program in Biochemistry and Cell 733A Biology, Stony Brook University, Stony Brook, NY. Dual roles of TAK1 in the important dengue vector Aedes aegypti. Shin-Hong Shiao. Department of Parasitology, National Taiwan 743B University, Taipei, Taipei, Taiwan. Identification and analysis of regulatory elements at the endogenous apterous locus. Dimitri Bieli1, Oguz Kanca1, Fisun 734B Hamaratoglu-Dion2, Daryl Gohl3, Paul Schedl3, Martin Müller1, A Targeted RNAi Screen of Maternally Deposited Cofactors in the Markus Affolter1. 1) University of Basel, Biozentrum, Basel, Drosophila Embryo. Adam N. Carte1,2, Max V. Staller2, Meghan Switzerland; 2) University of Lausanne, Switzerland; 3) Princeton D. Bragdon2, Ben Vincent2, Zeba B. Wunderlich2, Angela H. University, NJ. DePace2. 1) West Virginia University, Morgantown, WV; 2) Department of Systems Biology, Harvard Medical School, Boston, 744C MA. Cis-regulatory elements controlling fiber-specific expression of muscle structural gene Troponin C at 41C. Maria Chechenova, 735C Sara Maes, Richard Cripps. Biol, Univ New Mexico, Albuquerque, The bromodomain protein tBRD-1 interacts with two new NM. members of the BET family and is required for gene activation in male germ cells. Ina Theofel, Tim Hundertmark, Renate 745A Renkawitz-Pohl, Christina Rathke. Developmental Biology, The activity of the en/inv imaginal disc enhancer depends on the Philipps Universität Marburg, Marburg, Hessen, Germany. genomic neighborhood. Yuzhong Cheng, Judith Kassis. Program in Genomics of Differentiation, NICHD, NIH, Bethesda MD 736A 20892. Dissecting the mechanism of Capicua- and Groucho-mediated repression in the terminal patterning system. Marta Forés1, Leiore 746B Ajuria1, Núria Samper1, Sergio González-Crespo1, Rona Tunable Control of Transcriptional Enhancers Using TAL- Grossman2, Ze'ev Paroush2, Gerardo Jiménez1,3. 1) IBMB-CSIC, Effectors: Computing Back the Magic. Justin Crocker1, Garth Parc Cientific de Barcelona, Barcelona, Spain; 2) Dept. of Ilsley2,3, David Stern1. 1) HHMI Janelia Farm, Ashburn, VA; 2) Developmental Biology and Cancer Research, IMRIC, The European Molecular Biology Laboratory, European Bioinformatics Hebrew University, Jerusalem, Israel; 3) ICREA, Barcelona, Institute, Wellcome Trust Genome Campus, Cambridge, United Spain. Kingdom; 3) Okinawa Institute of Science and Technology Graduate University, Japan. 737B INO80-dependent regression of transcriptional responses regulates 747C developmental timing in Drosophila. Sarah Neuman, Robert Ihry, Global analysis of early nervous system specification. Lea Arash Bashirullah. University of Wisconsin-Madison, Madison, Daempfling, Robert P. Zinzen. BIMSB, MDC Berlin, Berlin, WI. Berlin, Germany.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

748A 757A Decoding the regulatory grammar at homeotic gene enhancers. Dissecting the cis-regulatory DNA that controls the POU-domain Robert Drewell1,3,4, Lauren Winkler4, Jessica Kurata4, Michael transcription factor genes, pdm-1 and pdm-2. Jermaine Ross1,2, Nevarez4, Lily Li4, Jacqueline Dresch2. 1) Department of Biology, Kuzin Alexander1, Thomas Brody1, Ward F. Odenwald1. 1) NIH, Amherst College, Amherst, MA; 2) Department of Mathematics, Bethesda, MD; 2) Brown University, Providence, RI. Amherst College, Amherst, MA, 01002; 3) Department of Biological Sciences, Mount Holyoke College, South Hadley, MA, 758B 01075; 4) Biology Department, Harvey Mudd College, Claremont, Spalt major directly regulates seven-up expression in Drosophila CA, 91711. oenocytes. Kathryn M. Ryan, Richard M. Cripps. Dept Biol, Univ New Mexico, Albuquerque, NM. 749B Identifying the enhancer region for singles bar expression in 759C Drosophila melanogaster myoblasts. Brayon Fremin, Tonya Deciphering the logic of Su(H)-dependent Notch-target enhancers. Brunetti, Richard Cripps. Biology Dept, UNM, Albuquerque, NM. Elizabeth Stroebele, Xin Yuan, Christian Noblett, Andrew Brittain, Albert Erives. Dept. of Biology, University of Iowa, Iowa 750C City, IA 52242, USA. Evolution of sex comb enhancers in the HOX gene Scr. Daniel Friedman, Olga Barmina, Artyom Kopp. Department of Evolution 760A and Ecology, University of California, Davis, Davis, CA. Multiple cis-regulatory elements regulate eyes absent expression in the developing retina. Bonnie Weasner, Justin Kumar. 751A Department of Biology, Indiana University, Bloomington, IN. The Abdominal-A Hox factor acts in the EGF signal receiving cell to promote oenocyte formation. Lisa M. Gutzwiller, David Li- 761B Kroeger, Brian Gebelein. Dev Biol, Cincinnati Children's Hosp, The Regulation and origin of sexually dimorphic segment number Cincinnati, OH. in Drosophila abdomen. Shun Yan, Wei Wang, John Yoder. University of Alabama, Tuscaloosa, AL. 752B Do regulatory interactions that result in repression of transcription 762C elongation dominantly interfere with activation by other enhancers The Chromatin Regulator Sin3A Buffers Transcriptional Changes at the same promoter? Michael L. Higgins1, Lisa Prazak2, Haiyue in the Somatic Musculature. Krista C. Dobi1, Marc S. Halfon2, Zhang3, John Peter Gergen4. 1) Graduate Program in Biochemistry Mary K. Baylies1. 1) Dept Dev Biol, Sloan-Kettering Inst, New and Structural Biology, Stony Brook University, Stony Brook, NY; York, NY; 2) Dept Biochemistry, SUNY Buffalo, Buffalo, NY. 2) Cold Spring Harbor Laboratory, Cold Spring Harbor, Stony Brook NY; 3) Nanjing University, Nanjing, China; 4) Department 763A of Biochemistry and Cell Biology and the Center for Krüppel regulation of hunchback increases reliability of mid- Developmental Genetics. embryo expression patterning. David M. Holloway1, Alexander V. Spirov2,3. 1) Dept Mathematics, British Col Inst Tech, Burnaby, 753C BC, Canada; 2) CEWIT and Computer Science, Stony Brook Tissue-specific cis-regulatory interactions in early Drosophila University, New York, USA; 3) Sechenov Institute of Evolutionary development. Sabrina Krueger, Robert P. Zinzen. BIMSB, MDC Physiology and Biochemistry St. Petersburg, Russia. Berlin, Berlin, Germany. 764B 754A Natural variation on the expression of developmentally essential Establishment of chromatin states during maternal to zygotic gene even-skipped in Drosophila melaogaster. Pengyao Jiang1, transition in Drosophila embryos. Xiao-Yong Li1, Melissa Michael Ludwig1, Martin Kreitman1,2, John Reinitz1,3. 1) Ecology Harrison2, Tommy Kaplan3, Michael Eisen1,4. 1) Howard Hughes & Evolution, University of Chicago, Chicago, IL; 2) Committee on Medical Institute, University of California, Berkeley, CA; 2) Dept Genetics, Genomics and Systems Biology, The University of of Biomolecular Chemistry, University of Wisconsin, Madison, Chicago, Chicago, IL; 3) Molecular Genetics & Cell Biology, The WI; 3) School of Computer Science and Engineering, The Hebrew University of Chicago, Chicago, IL. University of Jerusalem, Jerusalem 91904, Israel; 4) Dept of Molecular and Cell Biology, Dept of Integrative Biology, QB3 765C Institute, University of California, Berkeley, CA. In vivo interpretation of morphogen gradients in neural development. Agnieszka Klawiter, Robert P. Zinzen. BIMSB, 755B MDC Berlin, Berlin, Germany. Tinman and Pannier Regulate a Mef2 Shadow Enhancer in the Drosophila Heart. TyAnna L. Lovato, Cheryl A. Sensibaugh, 766A Kirstie L. Swingle, Melody M. Martinez, Richard M. Cripps. Biol, Regulation of ligand transcription mediates signaling pathway Univ New Mexico, Albuquerque, NM. crosstalk. Noemie Ammeux1, Ben Housden1, Norbert Perrimon1,2. 1) Department of Genetics, Harvard Medical School, Boston, MA; 756C 2) Howard Hughes Medical Institute, 77 Avenue Louis Pasteur, Complex Cis-Regulation of the Drosophila Genome: Insights from Boston, MA. the modENCODE Project. Steve W. Miller1, Nicholas Negre2, Matthew Slattery2, Chris Bristow3, Jia Chen2, Rachel Selfon3, Lijia 767B Ma2, Manolis Kellis3, Kevin P. White2, James W. Posakony1. 1) FlyBase Gene Model Annotations: The Rule-Benders. Madeline Div of Bio/CDB, UCSD, San Diego, CA; 2) Institute for Genomics Crosby, Gil dos Santos, Sian Gramates, Beverley Matthews, Susan & Systems Biology, Dept of Human Genetics, Univ of Chicago, E. St. Pierre, David Emmert, Pinglei Zhou, Andrew Schroeder, Chicago, IL; 3) Comp Sci and Artificial Intelligence Lab, Broad Kathleen Falls, Susan Russo, William Gelbart, FlyBase Inst of MIT and Harvard, Cambridge MA. Consortium. FlyBase, Harvard University, Cambridge, MA.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

768C 778A Expression of the RpL22e family: Evidence for tissue-specific Nucleosomes shape DNA polymorphism and divergence. Sasha A. post-translational modification of RpL22e-like in the fly eye. Brett Langley1, Charles H. Langley2, Gary H. Karpen1,3. 1) Life W. Gershman, Michael G. Kearse, Vassie C. Ware. Biological Sciences Division, Lawrence Berkeley National Laboratory, Sciences, Lehigh University, Bethlehem, PA. Berkeley, CA; 2) University of California, Davis, Department of Evolution and Ecology, Davis, CA; 3) University of California, 769A Berkeley, Department of Molecular and Cellular Biology, An editing-independent function for the Drosophila dADAR Berkeley, CA. mRNA truncated isoform during rnp-4f 5’-UTR intron splicing regulation. Sushmita Ghosh, Yaqi Wang, John Cook, Lea Chhiba, 779B Jack Vaughn. Biology, Miami University, Oxford, OH. The Influence of the Chd1 on puffing pattern in polytene chromosomes during drosophila development. Anna Makase, 770B Alexander Konev. St. Petersburg Nuclear Physics Institute, Allele spesific expression in heterozygous D. melanogaster Gatchina, Russian Federation. embryos. Tevfik H. Kitapci, Srna Vlaho, Jessica Gabrielian, Daniel Campo, Sergey Nuzhdin. Molecular and Computational 780C Biology, USC, Los Angeles, CA. HP1B’s role in gene regulation and chromatin structure. Louis Watanabe, Nicole Riddle. Biology, University of Alabama at 771C Birmingham, Birmingham, AL. Is there evidence for Dosage Compensation in Strepsiptera? Shivani Mahajan, Doris Bachtrog. Integrative Biology, 781A University of California , Berkeley, US. Structure-Function Studies of Drosophila Myb-Interacting Protein Mip120. MeiHsin Cheng1, Laura Andrejka2, Joseph Lipsick1,2,3. 1) 772A Genetics, Stanford University , Stanford, CA; 2) Pathology, Role of regulatory small peptides in the control of gene expression Stanford University , Stanford, CA; 3) Biology, Stanford during cell morphogenesis. Emilie Benrabah1,2, Jennifer Zanet1,2, University , Stanford, CA. Tongchao Li3, Hugo Bellen3, Francois Payre1,2, Serge Plaza1,2. 1) Centre de Biologie du development, Universite Paul Sabatier, 782B Toulouse, France; 2) CNRS UMR5547, Toulouse, France; 3) Neocentromere formation in Drosophila. Jason T. Palladino, Baylor College of Medicine, Houston, Texas, USA. Barbara Mellone. Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT. 773B Alternative splicing of Drosophila nmnat functions as a switch 783C between NAD synthetic and neuroprotective functions. Kai Ruan, Analyzing the co-evolution of CENP-A, CAL1, and centromeric Chong Li, Shaoyun Zang, R.Grace Zhai. MCP, Miller School of DNA in Drosophila. Leah Rosin, Barbara Mellone. Molecular and Medicine, University of Miami, Miami, FL. Cell Biology, University Of Connecticut, Storrs, CT.

774C 784A FlyBase Gene Model Annotations: Impact of High Throughput Monitoring the influence of CHD1 on histone dynamics in Data. Susan E. St. Pierre, Beverley Matthews, Madeline Crosby, Drosophila melanogaster. Michael A. Erb, Jennifer A. Gil dos Santos, Sian Gramates, David Emmert, Pinglei Zhou, Armstrong. W.M. Keck Science Department, Claremont McKenna Andrew Schroeder, Kathleen Falls, Susan Russo, William Gelbart, College, Claremont, CA. FlyBase Consortium. FlyBase, Harvard University, Cambridge, MA. 785B A candidate screen to identify factors important for CHD1 in Drosophila melanogaster. Sharon Kim, Jennifer Armstrong. Chromatin and Epigenetics W.M. Keck Science Department, Scripps College, Claremont, CA.

786C

The role of centromeric protein misregulation in aneuploidy and 775A cancer. Nicole L. Beier1,2, Gary H. Karpen1,2. 1) Department of The chromatin landscape of Drosophila: comparisons between Molecular and Cell Biology, University of California, Berkeley, sexes, species, and chromosomes. Emily Brown, Doris Bachtrog. Berkeley, CA; 2) Department of Genome Biology, Life Sciences Department of Integrative Biology, University of California, Division, Lawrence Berkeley National Laboratory, Berkeley, CA. Berkeley, Berkeley, CA.

787A 776B Understanding the regulation of expression and stability of the How does Ago2 contribute to dosage compensation in Drosophila SIN3 isoforms. Ashlesha M. Chaubal, Ambikai Gajan, Lori Pile. melanogaster? Nikita Deshpande, Victoria Meller. Department of Biological Sciences, Wayne State University, Detroit, MI. Biological Sciences, Wayne State University, Detroit, MI.

788B 777C The signature of repressed enhancers during Drosophila pattern The Genetic Basis of Paris Sex-Ratio Drive in Drosophila formation. Nina Koenecke1,2, Samuel Meier1, Jeffrey Johnston1, simulans. Quentin Helleu1,2, Pierre Gérard1, David Ogereau1, Julia Zeitlinger1,3. 1) Stowers Institute for Medical Research, Benjamin Prud'homme3, Catherine Montchamp-Moreau1. 1) Kansas City, MO, USA; 2) The Open University, UK; 3) Laboratoire Evolution Génomes & Spéciation, CNRS, Gif sur University of Kansas Medical Center, Department of Pathology Yvette, France; 2) Université Paris XI, Orsay, France; 3) Institut de and Cell Biology, Kansas City, KS, USA. Biologie du Developpement de Marseille-Luminy, Aix-Marseille

Université, Marseille, France.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

789C 797B Histone H3S10 Phosphorylation by the JIL-1 Kinase in Pericentric Novel Roles of Helicases in Preventing Aberrant Recombination Heterochromatin and on the 4th Chromosome Creates a Composite Repair in Heterochromatin. Taehyun Ryu, Kate Bowlin, Devika H3S10phK9me2 Epigenetic Mark. Chao Wang, Yeran Li, Weili Das, Irene Chiolo. Molecular and Computational Biology Cai, Xiaomin Bao, Jack Girton, Jorgen Johansen, Kristen Department, University of Southern California, Los Angeles, CA. Johansen. Biochemistry, Biophysics & Mol Biol, Iowa State University, Ames, IA. 798C Identification and Characterization of Novel Regulators of 790A Heterochromatin Structure and Function. Joel Swenson1,2, Serafin Drosophila Rm62 and SU(VAR)3-9 complex targeted by a 5’ non Colmenares2, Sylvain Costes3, Gary Karpen1,2. 1) Molec & Cell coding midsized RNA for Heterochromatin assembly. Indira Biol, Univ California-Berkeley, Berkeley, CA; 2) Department of Bag1, Manika Pal-Bhadra1, J. Boeke3, Axel Imhof3, Utpal Bhadra2. Genome Dynamics, Lawrence Berkeley National Laboratory, 1) Centre for Chemical Biology, Indian Institute of Chemical Berkeley, CA; 3) Department of Cancer and DNA Damage Technology, Tarnaka, Uppal road, Hyderabad 500007, Andhra Response, Lawrence Berkeley National Laboratory, Berkeley, CA. Pradesh, India; 2) Functional Genomics and Gene Silencing Group, Centre for Cellular and Molecular Biology, Hyderabad- 799A 500007, India; 3) 3Munich Center of Integrated Protein Science Illuminating the onset of late replication and and Adolf-Butenandt Institute, Ludwig Maximilians University of heterochromatinization of particular repetitive sequences during Munich, Munich, Germany. Drosophila embryogenesis using TALE-lights. Kai Yuan, Tony Shermoen, Patrick O'Farrell. Biochemistry & Biophysics, UCSF, 791B San Francisco, CA. Understanding Heterochromatin: Determination of DNA Elements That Influence Gene Expression. April Bauer, Sarah Elgin. 800B Department of Biology, Washington University, St. Louis, MO. Dissection of a domain border in the bithorax complex. Welcome Bender. BCMP Dept, Harvard Medical Sch, Boston, MA. 792C Heterochromatin Function and Dynamics by the KDM4A 801C Demethylase. Serafin U. Colmenares1, Sasha Langley1, Cameron Mechanism of Homie insulator-mediated long-range interaction. Kennedy1, Irene Chiolo2, Joel Swenson1, Axel Imhof3, Gary Miki Fujioka, James B. Jaynes. Biochemistry & Molecular Karpen1. 1) Genome Dynamics, Lawrence Berkeley National Lab, Biology, Thomas Jefferson University, Philadelphia, PA. Berkeley, CA; 2) Dept of Biological Sciences, University of Southern California, Los Angeles, CA; 3) Adolf Butenandt Institut, 802A University of Munich, Germany. The RNA-binding protein CIP3 antagonizes gypsy chromatin insulator function in a tissue-specific manner. Matthew R. King, 793A Leah H. Matzat, Ryan K. Dale, Su Jun Lim, Elissa P. Lei. Targeting Heterochromatin Formation in Drosophila. Sarah C. R. Laboratory of Cellular and Developmental Biology, NIDDK, NIH, Elgin, Monica Sentmanat, Kiri Ulmschneider, Tingting Gu. Dept Bethesda, MD. Biology, Washington Univ, St Louis, MO. 803B 794B The chromatin state-dependent TRL binding conservation in Development of a single break system to study DNA damage Drosophila species. Lijia Ma1, Matthew Slattery2, Nicolas Negre3, repair in heterochromatin. Aniek Janssen1,2, Jan LaRocque3, Gary Robert Arthur1, Rebecca Spokony1, Sasha Ostapenko1, Ryan Karpen1,2. 1) Genome Dynamics, Life Sciences Division, Ptashkin1, Jennifer Zieba1, Kevin White1. 1) University of Chicago, Lawrence Berkeley National Laboratory, Berkeley, CA; 2) Chicago, IL., US; 2) University of Minnesota, Duluth, MN., US; 3) Department of Molecular and Cell Biology, University of University of Montpellier, Montpellier, France. California Berkeley, Berkeley, California, USA; 3) Department of Human Science, School of Nursing & Health Studies, Georgetown 804C University, Washington DC, USA. Cis-elements mediating epigenetic regulation of eyeless locus in Drosophila melanogaster. Shreekant Verma, Rashmi U. Pathak, 795C Rakesh K. Mishra. Centre for Cellular and Molecular Biology - Centromeric variation in natural populations of Drosophila CSIR, Hyderabad-07, India. melanogaster. Charles H. Langley1, Gary H. Karpen2,3, Sasha A, Langley2. 1) Dept, of Evolution and Ecology, Univ California - 805A Davis, Davis, CA; 2) Life Sciences Division, Lawrence Berkeley De novo establishment of PcG-mediated repression. Jumana S. National Laboratory, Berkeley, CA; 3) University of California, AlHaj Abed, Rick Jones. Southern Methodist University, Dallas, Berkeley, Department of Molecular and Cellular Biology, TX. Berkeley, CA. 806B 796A Cyclin G, a link between epigenetic regulation of gene expression Ator, a Novel AT-hook Protein Co-purifies with Chromator and and developmental stability? Camille Dupont1, Delphine Localizes to the Chromocenter and Interband Regions of Polytene Dardhalon-Cuménal1, Valérie Ribeiro1, Vincent Debat2, Frédérique Chromosomes. Yeran Li1, Peng Wang2, Changfu Yao1, Jack Peronnet1, Neel B. Randsholt1. 1) UMR7622 - Developmental Girton1, Vincent Archambault2, Kristen Johansen1, Jorgen Biology, CNRS-UPMC, Paris, France; 2) UMR7205 - OSEB, Johansen1. 1) Biochemistry, Biophysics & Molecular Biology, Systematic and Evolution, CNRS-MNHN, Paris, France. Iowa State University, Ames, IA; 2) Institut de Recherche en Immunologie et en Cancérologie, Montreal, Canada.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

807C 818B Deciphering the functions of Ino80, a chromatin remodeling Trans--Activation: A New Epigenetic Phenomenon Responsible protein, in Drosophila development. Mohsen Ghasemi1, Vasanthi for Transcriptional Memory. Davide Corona, Maria Cristina Dasari2, Shruti Jain1, Narendra Pratap Singh2, Rakesh K. Mishra2, Onorati, Walter Arancio. STEBICEF, Universita di Palermo, Vani Brahmachari1. 1) Dr. B. R. Ambedkar Center for Biomedical Palermo, Italy. Research, Delhi University, Delhi, India; 2) Centre for Cellular and Molecular Biology, Hyderabad, India. 819C Presence of assymetic CpC methylation in Drosophila 808A melanogaster. Deepti D. Deobagkar1,2, Chitra Pannikar1, Polycomb group regulation of engrailed and invected. Judith A. Abhyankar Varada1, Deshmukh Saniya1. 1) Zoology, University of Kassis, Sandip De, Yuzhong Cheng. NICHD/NIH, Bethesda, MD. Pune, Pune, India, 411007; 2) Bioinformatics center, University of Pune, Pune, India, 411007. 809B Identifying new Polycomb group genes by screening for mutations 820A that disrupt pairing-sensitive silencing. James A. Kennison. Identifying the Genetic Components of Hybrid Sterility in Genomics of Differentiation, Eunice Kennedy Shriver National Drosophila virilis. Mauricio Galdos1,2, Alex Erwin1, Chris Institute of Child Health and Human Development, NIH, Bethesda, Harrison1, Justin Blumenstiel1. 1) Ecology and Evolutionary MD. Biology, The University of Kansas, Lawrence, KS; 2) Molecular Biosciences, The University of Kansas, Lawrence, KS. 810C Genome-wide functions for Polycomb complexes. Hun-Goo Lee1, 821B Yuri Schwartz2, Tatyana Kahn2, Amanda Simcox3, Vincenzo Defining the roles of chromatin environment in DNA replication Pirrotta1. 1) Molecular Biology and Biochemistry Dept, Rutgers origin activation. Brian Hua1,2, Terry Orr-Weaver1,2. 1) Whitehead University, Piscataway, NJ; 2) Molecular Biology Dept, Umeå Institute, Cambridge, MA; 2) MIT Biology, Cambridge, MA. University, Umeå, Sweden; 3) Molecular Genetics Dept, Ohio State University, Columbus, OH. 822C Evaluation of genes required for cell survival after telomere loss. 811A Rebeccah Kurzhals1, Cory Parks1, Hailey Lowery1, Jenny Dynamic and differential targeting of Polycomb complexes during Atanasov2, Zachary Lee3. 1) Department of Biology, Southeast Drosophila development. Anne-Marie Martinez, Anna Delest, Missouri State University, Cape Girardeau, MO; 2) University of Aubin Thomas, Bernd Schuttengruber, Samy Sakr, Giacomo California San Diego, California 92093; 3) University of Utah, Salt Cavalli. Institute of Human Genetics, CNRS, Montpellier, Lake City, UT 84112. Languedoc-Roussillon, France. 823A 812B The SUUR Chromatin Protein Promotes Underreplication Through Polycomb/ Trithorax group proteins collaborate with Inhibition of Replication Fork Progression. Jared T. Nordman1, Heterochromatin protein 1 to regulate Drosophila gene expression. Elena Kozhevnikova2, Peter Verrijzer2, Alexey Pindyurin3, Janel Rodriguez, Jamila Horabin. Biomedical Science, Florida Evgeniya Andreyeva4, Victor Shloma4, Igor Zhimulev4, Terry L. State University, Tallahassee, FL. Orr-Weaver1,5. 1) Orr-Weaver Lab, Whitehead Inst, Cambridge, MA; 2) Erasmus Univ. Med. Center, Rotterdam, Netherlands; 3) 813C Netherlands Cancer Institute, Amsterdam, Netherlands; 4) Russian A screen of chromatin modifier mutants in Drosophila wing disc Acad. Sciences, Novosibirsk, Russia; 5) Dept. of Biology, regeneration using a non-surgical ablation system. Yuan Tian, Massachusetts Institute of Technology, Cambridge, MA. Rachel Smith-Bolton. Cell & Developmental Biology, University of Illinois Urbana-Champaign, Urbana, IL. 824B Faithful Transmission of Paternal Telomeres Ensured by a Sperm- 814A Specific Chromosomal Protein. Takuo Yamaki1, Glenn Yasuda2, What makes the X unique: an X-clusive sequence story. Sonal S. Barbara Wakimoto1. 1) Department of Biology, University of Joshi, Victoria H. Meller. Department of Biological Sciences, Washington, Seattle, WA 98195; 2) Department of Biology, Wayne State University, Detroit, MI. Seattle University, Seattle, WA 98122.

815B The function of the dosage compensation protein, CLAMP, at the RNA Biology histone locus body. Leila E. Rieder, Anna Zeidman, Erica Larschan. Molecular Biology, Cellular Biology and Biochemistry, Brown University, Providence, RI. 825C MicroRNA-mediated Regulation of Apoptosis in Drosophila. 816C 1,2 2 2,4 Cohesin-independent connections between sister chromatids and Chao-Yi Chen , Jian-Chiuan Li , Kun-Nan Tsai , Chi-Chuan Li2,5, Hsi-Ju Chen2, Haixia Huang3, Wan-Hsuan Lin2, Bruce A. their relationship to homolog pairing. Tharanga Niroshini 3 2,3 Senaratne, Eric Joyce, Chao-ting Wu. Genetics, Harvard Medical Hay , Chun-Hong Chen . 1) Institute of Molecular and Cellular School, Boston, MA. Biology, National Taiwan University, Taipei, Taiwan; 2) Division of Molecular and Genomic Medicine, National Health Research 817A Institutes, Zhunan Mioali, Taiwan, Taiwan; 3) Division Of Investigating the role of chromatin remodeler CHD1 in the Biology, Mc 156-29, California Institute Of Technology, nucleolus of D. melanogaster. Lauren S. Siems, Jennifer Pasadena, CA. USA; 4) Institute of Molecular Medicine, National Armstrong. Biology, Scripps College, Claremont, CA. Tsing Hua University, Hsinchu, Taiwan; 5) Institute of Biotechnology, National Tsing Hua University, Hsinchu, Taiwan.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

826A 834C MicroRNAs regulates the neuronal and developmental timing. Core snRNP splicing factor SmD1 modulates RNA interference in Chu-Ya Cheng1, Kun-Nan Tsai1,2, Jian-Chiuan Li1, Hung-Hsiang Drosophila. Xiao-Peng Xiong1, Krishna Kurthkoti1, Kung-Yen Yu3, Chun-Hong Chen1. 1) Institute of Molecular and Genomic Chang1, Gianluigi Lichinchi1, Nabanita De2, Anette Schneemann3, Medicine, National Health Research Institutes, Zhunan, Taiwan; 2) Ian J. MacRae2, Tariq M. Rana1, Norbert Perrimon4, Rui Zhou1. 1) Institute of Molecular Medicine, National Tsing Hua University, Program for RNA Biology, Sanford-Burnham Medical Research Hsinchu, Taiwan; 3) Institute of Cellular and Organismic Biology, Institute, La Jolla, CA; 2) Department of Integrative Structural and Academia Sinica, Taipei, Taiwan. Computational Biology; 3) Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA; 4) Howard 827B Hughes Medical Institute, Department of Genetics, Harvard Unbiased screening by conditional competitive inhibition reveals Medical School, Boston, MA. novel functions of conserved Drosophila miRNAs during development and adult behavior. Elizabeth M. McNeill1, Tudor A. 835A Fulga1,6, Richard Binari2, Julia Yelick1, Alexandra Blanche1, Circular RNA transcripts in Drosophila melanogaster Matthew Booker2, Michael Schnall-Levin2, Yong Zhao2, Todd development. Shannon Hateley1, Lior Pachter1,2, Michael Eisen1,3. DeLuca3, Fernando Bejarano4, Zhe Han5, Eric C. Lai4, Dennis 1) Department of Molecular and Cell Biology, University of Wall3, Norbert Perrimon2, David Van Vactor1. 1) Cell Biology, California, Berkeley, CA; 2) Department of Mathematics, Harvard Medical School, Boston, MA; 2) Genetics, Harvard University of California, Berkeley, CA; 3) Howard Hughes Medical School, Boston, MA; 3) Systems Biology, Harvard Medical Institute, University of California, Berkeley, CA. Medical School, Boston, MA; 4) Developmental Biology, Sloan- Kettering Institute, New York, NY; 5) Internal Medicine- 836B Molecular Medicine, Genetics and Cell and Developmental Acal, a long non-coding RNA that collaborates with Raw to Biology, University of Michigan Medical School, Ann Arbor, MI; downregulate JNK signaling during dorsal closure. Luis Daniel 6) Weatherall Institute of Molecular Medicine, Radcliffe Ríos-Barrera, Juan Riesgo-Escovar. Dev Biology., Neurobiology Department of Medicine, University of Oxford, Oxford, UK. Inst, Univ Nacional Autónoma de México, Querétaro, Juriquilla, Mexico. 828C Sexual divergence by global and coordinated reductions in 837C microRNA abundance and 3'UTR length in spermatogenesis. Tropomyosin protein expression is regulated by a novel coding Yang Shen1, Bitao Qiu1, Chung-I Wu1,2,3. 1) State Key Laboratory region determinant. Nathan Boin, Jessica Williams, Aaron N. of Biocontrol, School of Life Sciences, Sun Yat-sen University, Johnson. Dept of Integrative Biology, University of Colorado Guang Zhou, P.R. China; 2) Department of Ecology and Denver, Denver, CO. Evolution, Univeristy of Chicago, Chicago, USA; 3) Laboratory of Disease Genomics and Individualized Medicine, Beijing Institute 838A of Genomics, Chinese Academy of Sciences, Beijing, P.R. China. Analysis of the nuclear localisation of castor-mRNA in Drosophila melanogaster. Antje Juengling1, Melanie Homberg2, Kathrin 829A Fischer1, Joachim Urban1. 1) Institute of Genetics, University of Genome-wide microRNA screening reveals that the evolutionary Mainz, Mainz, Germany; 2) TRM Leipzig, Dpt. for Cell and conserved microRNA-9a regulates body growth by targeting Development Biology, Leipzig, Germany. sNPFR1/NPYR. Yoon Seok Suh1,2, Kweon Yu1,2. 1) Bionano Research Center, KRIBB, Daejeon, South Korea; 2) Department of 839B Functional Genomics, KUST, Daejeon, South Korea. Identification of a conserved motif in mRNAs that localize to RNA islands during Drosophila embryogenesis. Stephanie Yee1, 830B Michelle Kowanda1, Xiao Li2, Quaid Morris3, Howard Lipshitz2, Characterization of subtelomeric regions involved in transposable Eric Lecuyer4, Paul Lasko1. 1) Biology, McGill University, element repression in Drosophila melanogaster. Amna Asif- Montreal, Quebec, Canada; 2) Molecular Genetics, University of Laidin. Université Pierre et Marie Curie, Paris, France. Toronto, Toronto, Ontario, Canada; 3) Computer Science, University of Toronto, Toronto, Ontario, Canada; 4) RNA Biology, 831C Institut de Recherches Cliniques de Montreal, Montreal, Quebec, Primary processing and Aub homotypic ping-pong cycle are acting Canada. in Drosophila primary spermatocytes to produce piRNAs. Emilie Quenerch'du1,2, Amit Anand1, Toshie Kai1,2. 1) Temasek Life 840C Sciences Laboratory, Singapore; 2) National University of Distinct neural mRNA decay kinetics in Drosophila Singapore, Department of Biological Sciences, Singapore. embryogenesis. Dana A. Burow, Maxine Umeh, Michael Cleary. Quantitative and Systems Biology, University of California, 832A Merced, Merced, CA. Cosuppression of Adh gene in Drosophila melanogaster by insertion of inducible transgene follows typical RNAi pathway. 841A Debabani Roy Chowdhury, Utpal Bhadra. Functional Genomics Stable intronic sequence RNAs (sisRNAs) in Drosophila Group, Centre for Cellular and Molecular Biology, Uppal Road, melanogaster. Jun Wei Pek, Eugene Gardner, Joseph Gall. Hyderabad - 500007, INDIA. Embryology, Carnegie Institution, Baltimore, MD.

833B 842B Dietary Restriction and the effects of the Syndecan gene on life New RNA-seq and RNAi data on the function of alternatively span in Drosophila. Thanhlong G. Tran1, Maria De Luca2, Jeff spliced exons in the complex Drosophila dumpy gene. Amber Leips1. 1) Dept of Biological Science, UMBC, Baltimore, MD; 2) Carmon, Ross MacIntyre. Dept Molec Biol & Genetics, Cornell Dept of Nutrition Sciences, University of Alabama at Birmingham, Univ, Ithaca, NY. Birmingham, AL.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

843C 853A Analysis of alternative splicing in Drosophila using RNA-sequence Ultrastructural characterization of cytokinesis and abscission in data. Lauren Gibilisco, Qi Zhou, Shivani Mahajan, Doris polarized epithelia cells using advanced TEM approaches. Irina Bachtrog. University of California, Berkeley, Berkeley, CA. Kolotueva, Emeline Daniel, Roland Le Borgne. IGDR, Rennes, France. 844A Decreased expression of 9G8 and sex determination genes alter 854B lipid droplet morphology and triglyceride levels in larvae. Bijal C. Microfluidic culturing for studying morphogenesis and gastrulation Kakrecha1, Robert M. Gingras3, Spencer Ng2, Justin R. in live Drosophila embryos. Thomas J. Levario1, Bomyi Lim2, DiAngelo3, Alexis Nagengast2. 1) Biology, Widener Univ, Chester, Jiyuan Ding1, Stanislav Y. Shvartsman2, Hang Lu1. 1) School of PA; 2) Biochemistry and Chemistry, Widener Univ, Chester, PA; Chemical and Biomolecular Engineering, Georgia Institute of 3) Biology, Hofstra Univ, Hempstead, NY. Technology, Atlanta, GA; 2) School of Chemical and Biological Engineering and Lewis-Sigler Institute for Integrative Genomics, 845B Princeton University, Princeton, NJ. A phylogenetic study of Drosophila splicing assembly chaperone RNP-4F associated U4-/U6-snRNA: a revised secondary structure. 855C Jack C. Vaughn, Sushmita Ghosh, Jing Chen. Dept Biology, The Transgenic RNAi Project (TRiP): new resources, online tools Miami Univ, Oxford, OH. and validation data. Ian T. Flockhart1, Yanhui Hu1, Charles Roesel1,3, Richelle Sopko1, Marianna Foos1, Colleen Kelley1, 846C Noemie Ammeux1, Norbert Perrimon1,2, Stephanie E. Mohr1, A new non-spliceosomal nuclear intron class in Drosophila rnp-4f. Lizabeth Perkins1. 1) Harvard Med Sch, Boston, MA; 2) HHMI, Yaqi Wang, Sushmita Ghosh, Angila Simone, Amy Feiber, Jack Boston, MA; 3) Northeastern U, Boston MA. Vaughn. Biology, Miami University, Oxford, OH. 856A 847A Development of novel CRISPR tools for genome editing in The effect of ALS-associated TDP-43 mutations on active Drosophila. Benjamin E. Housden1, Yanhui Hu1, Charles Roesel3, translation of specific RNAs using polysome profiling and RNA- Ian Flockhart1, Shuailiang Lin1, Colleen Kelley1, Rong Tao1, seq. Scott G. Daniel1, Antony Pearson1, Daniela C. Zarnescu1,2,3. Michael Buckner1, Laura Holderbaum1, Stephanie Mohr1, Norbert 1) Molecular and Cellular Biology Dept, University of Arizona, Perrimon1,2. 1) Department of Genetics, Harvard Medical School, Tucson, AZ; 2) Neuroscience Dept, University of Arizona, Tucson, Boston, MA; 2) Howard Hughes Medical Institute, Harvard AZ; 3) Neurology Dept, University of Arizona, Tucson, AZ. Medical School, Boston, MA; 3) Northeastern University, Boston, MA. 848B Orb and Wispy cooperate in the cytoplasmic polyadenylation of 857B grk mRNA during oogenesis. Amanda Norvell, Lauren Langbein, Genome engineering and RNAi resources at the Drosophila RNAi Kristen Randolph, Letitia Thompson. Dept Biol, Col of New Screening Center. Stephanie E. Mohr1, Yanhui Hu1, Ian T. Jersey, Ewing, NJ. Flockhart1, Quentin Gilly1, Michael Buckner1, Benjamin E. Housden1, Gerald Marsischky1, Charles Roesel1,2, Shuailiang Lin1, 849C Bahar Yilmazel1, Kirstin Rudd1, Norbert Perrimon1,3. 1) Dept Gen, gurken (grk) mRNA is alternatively polyadenylated. Letitia Harvard Med Sch, Boston, MA; 2) Northeastern University, Thompson, Amanda Norvell. Biology, The College of New Boston, MA; 3) Howard Hughes Medical Institute, Boston, MA. Jersey, Ewing, NJ. 858C 850A A versatile toolbox for CRISPR/Cas-mediated engineering of the The RNA export pathway and regulation of tissue specific gene Drosophila genome. Fillip Port1, Hui-Min Chen2, Tzumin Lee2, expression. Simona Caporilli, Yachuan Yu, Jianqiao Jiang, Helen Simon Bullock1. 1) MRC Laboratory of Molecular Biology, White-Cooper. Sch Biosci, Cardiff Univ, Cardiff, United Cambridge, United Kingdom; 2) Janelia Farm Research Campus, Kingdom. HHMI, Ashburn, VA.

859A High performance gene expression profiling of D melanogaster, Techniques and Resources and host-parasite interactions. MM Kańdula1, S. Shridhar1, N. Stralis-Pavese1, DP Kreil1,2. 1) Chair of Bioinformatics, BOKU

University, Vienna, Austria; 2) School of Life Sciences, University of Warwick, U.K. 851B Three-dimension magnetic resonance microscopy of the 860B Drosophila brain at 10 micron isotropic resolution. Pedro New methods for translational profiling of sensory neurons of 1,2 2 2,3 Fernandez-Funez , Choong Lee , Steve Blackband . 1) Dept Drosophila larvae. Andrew Bellemer1, Sherry Tang2, W. Daniel Neurology, Univ Florida, Gainesville, FL; 2) Dept. Neuroscience, Tracey1,3,4. 1) Department of Anesthesiology, Duke University, Univ. of Florida, Gainesville, FL; 3) National High Magnetic Field Durham, NC; 2) Department of Biology, Duke University, Laboratory. Durham, NC; 3) Department of Neurobiology, Duke University, Durham, NC; 4) Department of Cell Biology, Duke University, 852C Durham, NC. Computational tissue labeling: Tissue and Cellular Recognition in 1 Developing Drosophila Embryos. Soile V. E. Keränen , Jonathan 861C 2 2 1 2 T. Barron , Pablo Arbeláez , Mark D. Biggin , Jitendra Malik , A Synthetic Non-amplyfing RNAseq Carrier. Peter A. Combs1, 1 David W. Knowles . 1) Lawrence Berkeley National Laboratory, Michael B. Eisen2,3. 1) Biophysics Grad Group, UC Berkeley, CA; Berkeley, CA; 2) University of California Berkeley, Berkeley, CA. 2) Molecular and Cell Biology, UC Berkeley, CA; 3) HHMI, UC Berkeley, CA.

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

Qian Sun1,2, Thomas Brody3, Jieping Ye1,2, Sudhir Kumar1,4. 1) 862A Center for Evolutionary Medicine and Informatics, Biodesign Large-scale identification of chemically induced mutations in Institute, Arizona State University, Tempe, AZ; 2) School of Drosophila melanogaster . Nele A. Haelterman1, Lichun Jiang2, Computing, Informatics, and Decision Systems Engineering, Yumei Li2, Vafa Bayat1,3, Berrak Ugur1, Kai Li Tan1, Ke Zhang4, Arizona State University, Tempe, AZ; 3) National Institutes of Danqing Bei2, Bo Xiong1, Wu-Lin Charng1, Hector Sandoval2, Health, Neural Cell-Fate Determinants Section, Bethesda, MD; 4) Shinya Yamamoto1,2, Manish Jaiswal2,5, Koen J. T. Venken1,6, Rui School of Life Sciences, Arizona State University, Tempe, AZ. Chen1,2, Hugo J. Bellen1,2,4,5. 1) Developmental Biology Program, Baylor College of Medicine, Houston, TX; 2) Department of 870C Molecular and Human Genetics, Baylor College of Medicine, A website consolidating multiple Drosophila species genome data. Houston, Tx; 3) Medical Scientist Training Program, Baylor Virginie Orgogozo. Institut Jacques Monod, CNRS UMR7592, College of Medicine, Houston, Tx; 4) Program in Structural and Paris, France. Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Tx; 5) Howard Hughes Medical Institute; 6) 871A Department of Biochemistry and Molecular Biology, Baylor A proposed standardized Drosophila thoracico-abdominal College of Medicine, Houston, Tx. ganglion nomenclature. Douglas Armstrong2, Jana Börner4, Gwyneth Card1, Robert Court2,3, Marta Costa5, Michael 863B Dickinson6, Carsten Duch7, Wyatt Korff1, Richard Mann8, David Prediction of genetic interactions from high-throughput RNA-Seq Merritt9, Rod Murphey4, Shigehiro Namiki1, Andrew Seeds1, of Drosophila deletion collections. Hangnoh Lee1, Dong-Yeon David Shepherd3, Troy Shirangi1, John Tuthill10, James Truman1, Cho2, Steven Russell3, Teresa Przytycka2, Brian Oliver1. 1) Darren Williams11. 1) HHMI- Janelia Farm; 2) School of National Institute of Diabetes, Digestive, and Kidney Diseases, Informatics, U. of Edinburgh; 3) School of Biol. Sci, Bangor National Institutes of Health, Bethesda, MD; 2) National Center University; 4) Biological Sciences, Florida Atlantic University; 5) for Biotechnology Information, National Institutes of Health, Dept. of Genetics, U. of Cambridge; 6) Dept. of Biology, U. of Bethesda, MD; 3) Department of Genetics, University of Washington; 7) Univ. of Mainz; 8) Biochemistry and Molecular Cambridge, Cambridge, United Kingdom. Biophysics, Columbia University; 9) School of Biological Sciences, The University of Queensland; 10) Department of 864C Neurobiology, Harvard Medical School; 11) MRC Centre for High-speed robotic system for handling live non-anesthetized adult Developmental Neurobiology, King's College London. Drosophila melanogaster for biological research. Joan Savall1,2, Eric Tatt Wei Ho1,3, Mark Schnitzer1,2. 1) James H. Clark Center 872B for Biomedical Engineering & Sciences, Stanford University, High rates of background mutagenesis induced by the hsFLP-FRT Stanford, CA; 2) Howard Hughes Medical Institute, Stanford targeted deletion method. David R. Andrew1,2, Robert Kraft2, University, Stanford, CA; 3) University Teknologi PETRONAS, Alvin J. Clark2, Judith Tello2, Monica Chaung2, Elise Blackmore2, Malaysia. Frank Valdes2, Linda L. Restifo1,2. 1) Center for Insect Science, University of Arizona, Tucson, AZ; 2) Department of 865A Neuroscience, University of Arizona, Tucson, AZ. Modeling a gene's expression from its intergenic sequence. Md A. Hassan Samee1, Tara Lydiard-Martin3, Angela DePace3, Saurabh 873C Sinha1,2. 1) Dept of Comp Sci, Univ of Illinois, Urbana, IL; 2) Regulated, inducible Cre for spatio-temporal mosaic analysis in Institute for Genomic Biology, Univ of Illinois, Urbana, IL; 3) Drosophila. Sougata Roy, Songmei Liu, Frank Hsiung, Thomas B. Dept of Systems Biology, Harvard Med School, Boston, MA. Kornberg. Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA. 866B Automated Image Annotation of Drosophila Embryos. Qian 874A Sun1,2, Stuart Newfeld3, Sudhir Kumar1,3,4, Jieping Ye1,2. 1) Center RMCE in Drosophila tissue-culture cells. Amanda Simcox, for Evolutionary Medicine and Informatics, Biodesign Institute, Thomas Jacobsen, Sathiya Manivannan, Bhavani Selvaraj. Dept Arizona State University, Tempe, AZ; 2) School of Computing, Molec Gen, Ohio State Univ, Columbus, OH. Informatics, and Decision Systems Engineering, Arizona State University, Tempe, AZ; 3) School of Life Sciences, Arizona State 875B University, Tempe, AZ; 4) Center of Excellence in Genomic Visualization of Sqd-grk Interactions in Live Drosophila Oocytes Medicine Research, King Abdulaziz Univ, Jeddah, Saudi Arabia. Using Tri-molecular Fluorescence Complementation. Nancy J. Levensailor, Steven J. Gangloff, Alicia R. Watson, Dane M. 867C Buenton, Nathanael R. Terwilliger, Scott B. Ferguson. Department Annotation of genes on the Drosophila biarmipes dot chromosome of Biology, SUNY Fredonia, Fredonia, NY. using comparative genomics. Alison Dubé, Benjamin Reid, Genevieve St. Martin, Tiffany Turner, James E. J. Bedard. 876C Department of Biology, University of the Fraser Valley, Analysis of temperature sensitivity of nine Rho1 alleles. Nicole K. Abbotsford, BC, Canada. Barnette1, Lauren Stone2, Laurence von Kalm1. 1) Biology, University of Central Florida, Orlando, FL; 2) Rollins College, 868A Winter Park, FL. GeneSeer Aids Drug Discovery by Exploring Evolutionary Relationships Between Genes Across Genomes. Douglas D. 877A Fenger, Matthew Shaw, Philip Cheung, Tim Tully. Bioinformatics Drosophila Habitat Developed to Support Research on the Department, Dart NeuroScience, San Diego, CA. International Space Station. Sharmila Bhattacharya, Matthew Lera, Ravikumar Hosamani. Space Biosciences Division, NASA 869B Ames Res Ctr, Mail stop 236-5. Moffett Field, CA 94035. FlyExpress 6: Discovering cis-regulatory motifs by integrative analysis of sequence and spatiotemporal patterns of expression. Charlotte E. Konikoff1, Bremen Braun1, Maxwell Sanderford1,

POSTER SESSIONS See Page 10 for presentation schedule. Poster board number and presenter are in bold. Full abstracts can be found online.

878B 887B Characterization of histidine decarboxylase bearing an internal An interdisciplinary project-based approach using Drosophila FLAG epitope in Drosophila melanogaster . Anthony Hage1, genetics and cell biology to improve reasoning, problem solving Maxwell Mianecke2, Andra Trapp1, Deb Burg1, Martin G. Burg1,2. and foundational knowledge in high school students. Sonia Hall1, 1) Biomedical Sciences, Grand Valley State Univ., Allendale, MI; Camden Hanzlick-Burton2. 1) Molecular Biosciences, University 2) Cell and Molecular Biology, Grand Valley State Univ., of Kansas, Lawrence, KS; 2) Olathe Northwest High School, Allendale, MI. Olathe, KS.

879C 888C Survey or Drosophila species on Santa Catalina Island. Joyce Y. A genetic screen for new dis3 alleles in Drosophila. Hemlata Kao, Sergey V. Nuzhdin. Biological Sciences, University of Mistry1, Mark Snee2, James Skeath2. 1) Dept of Biology, Widener Southern California, Los Angeles, CA. University, Chester, PA; 2) Dept of Genetics, Washington University Medical School, St Louis, MO. 880A Novel vectors for tracking multiple transgenes within a single 889A Drosophila strain. David Li-Kroeger1, Hugo Bellen1,2,3. 1) Using an undergraduate course to map and clone adult visible Molecular and Human Genetics, Baylor College of Medicine, mutations. Eric P. Spana. Department of Biology, Duke Houston, TX; 2) Graduate Program in Developmental Biology, University, Durham, NC. Baylor College of Medicine, Houston, TX; 3) Howard Hughes Medical Institue, Baylor College of Medicine, Houston, TX. 890B The Genomics Education Partnership: Implementing a Research- 881B Based Genomics Project for Undergraduates. S. Elgin1, C. New stocks at the Bloomington Drosophila Stock Center. Annette Bazinet2, J. Bedard3, M. Burg4, J. DiAngelo5, C. Jones6, L. L. Parks, Kevin R. Cook, Thom C. Kaufman, Kathy A. Matthews. Kadlec7, J. Leatherman8, H. Mistry9, A. Nagengast9, L. Reed10, NL Bloomington Drosophila Stock Center, Dept. of Biology, Indiana Reeves11, J. Sanford12, C. Small13, S. Smith14, L. Zhou15, C. University, Bloomington, IN. Shaffer1, W. Leung1, D. Lopatto16. 1) Washington U St Louis, MO; 2) St John's U, NY; 3) U Fraser Valley, BC; 4) Grand Valley St U, 882C MI; 5) Hofstra U, NY; 6) Moravian Col, PA; 7) Wilkes U, PA; 8) Geometric morphometric analysis reveals opposing effects of PVR U Northern Colorado, CO; 9) Widener U, PA; 10) U Alabama- and JNK signaling on thorax morphology. Lewis Baker1, Rebecca Tusc, AL; 11) Mt San Jacinto Col, CA; 12) Ohio Northern U, OH; Garlena1, Trish Parsons2, Seth Weinberg2, Beth Stronach1. 1) 13) Medgar Evers Col, NY; 14) Arcadia U, PA; 15) U Pittsburg, Dept Micro & Mol Genetics, Univ Pittsburgh Sch Medicine, PA; 16) Grinnell Col, IA. Pittsburgh, PA; 2) Dept Oral Biology, Univ Pittsburgh Sch Dental Medicine, Pittsburgh, PA. 891C Implementation of the Genomics Education Partnership (GEP) 883A Project at a Community College. Nick L. Reeves1, Céline Gerber1, An intersectional genetic approach that is interoperable with Astrid Russell1, Gabriel A. Sanchez1, Ursula Simonoski1, Curtis C. existing GAL4 lines. Shamprasad Varija Raghu1, Claudia Smith1, Robert Haywood1, Maureen Njuguna1, Wilson Leung2, Barros1, Farhan Mohammad1, Joanne Lam1, Sadhna Sahani1, Adam Christopher D. Shaffer2, Sarah C. R. Elgin2. 1) Biological Claridge-Chang1,2. 1) Program in Neuroscience and Behavior, Sciences, Mt. San Jacinto College, Menifee, CA; 2) Biology Duke-NUS Graduate Medical School, Singapore; 2) Institute for Department, Washington University, St Louis, MO. Molecular and Cell Biology, Singapore.

884B Weak imaginal disc GAL4 drivers can be used to express toxic UAS responder constructs throughout development. Minpei Wang, Mariah Pero, Laurence von Kalm. Department of Biology, University of Central Florida, Orlando, FL.

885C National BioResource Project “Drosophila” --- Fly Stock Centers Consortium in Japan. Masayoshi Watada1, Toshiyuki Takano2, Muneo Matsuda3, Ryo Akashi4, Ryu Ueda5. 1) Dept Biol, Fac Sci, Ehime Univ, Matsuyama, Ehiem, Japan; 2) Drosophila Genetic Resource Center, Kyoto Institute of Technology, Japan; 3) School of Medicine, Kyorin University, Japan; 4) Frontier Science Research Center, University of Miyazaki, Japan; 5) Genetic Resource Center, National Institute of Genetics, Japan.

Educational Initiatives

886A Melanogaster...Catch the fly! The video game. Josefa Gonzalez1, Roberto Torres2. 1) Institute of Evolutionary Biology, Barcelona, Barcelona, Spain; 2) Torresdecomunicacion, Barcelona, Spain.

SPEAKER AND AUTHOR INDEX

This index includes names and speakers for the Opening General Session and for Plenary Sessions I and II, and names of all authors of programmed abstracts. The number following the author’s name refers to the abstract program number. A, B, or C following a number indicates a poster presentation. The presenting author of an abstract is noted with an asterisk. Please note that the complete abstracts are available at http://www.genetics- gsa.org/drosophila/2014/pages/abstracts.shtml

Al-Ouran, Rami, 739A Alpar, Lale, 305B* Altschuler, Dylan, 10 A Altschuler, Steven, 10 Alvi, Zain A., 370A* Abadir, Peter M., 615C Amaral, Luís, 111 Abdallah, Abbas, 235A* Amaral, Nuno, 250A Abdu, Uri, 171C Ammeux, Noemie, 766A*, 855C Abernethy, John, 84 Amoyel, Marc, 305B Abidi, Syeda Nayab Fatima, 310A*, 314B Amrein, Hubert, 532A, 533B Ables, Elizabeth T., 384C* Anand, Amit, 831C Abreu-Blanco, Maria, 178A Anderl, Ines, 448A Abreu-Goodger, Cei, 654C Andersen, Ditte, 6 Abud, Helen E., 418A Anderson, James, 557B Acebes, Ángel, 558C Anderson, Stephen, 371B* Acevedo, Julieta, 316A Andrejka, Laura, 781A Achal, Madhulika, 330C Andres, Andrew, 247A Acurio, Andrea E., 684C Andres-Terre, Marta, 453C Adachi, Mai, 211A* Andrew, David R., 872B* Adachi-Yamada, Takashi, 288C, 355A Andrew, Deborah, 23, 407B Adams, Alison F., 668B* Andrew, Deborah J., 356B, 408C Adams, Melanie, 724A Andreyeva, Evgeniya, 823A Adler, Paul, 186C Andrianov, Boris V., 645C Adler, Paul N., 413B Andriatsilavo, Maheva, 435C* Adrian, Andrew, 626B* Anguiano-Zarate, Stephanie, 79 Aerts, Stein, 508A Anholt, Robert R. H., 529A, 623B Affolter, Markus, 252C, 743B Anisiforov, Denis, 635B* Agi, Egemen, 10* Anjalika, Chongtham, 556A Agrawal, Namita, 556A*, 578B Anllo, Lauren, 409A* Aguilar, Berenice, 140 Anna, Chekunova, 627C Aguilera, Martin, 545B Antoniewski, Christophe, 89 Aguilera, Milton, 316A Antunes, Marco, 312C A. Hay, Bruce, 825C Apoznanski, Theresa, 727A Ahmad, S. M., 405C* Apweiler, Rolf, 107 Ainsley, Joshua, 144 Aquadro, Charles, 637A Ajjuri, Rami, 599B Aradhya, Rajaguru, 153 Ajjuri, Rami R., 456C, 557B* Arancio, Walter, 818B Ajuria, Leiore, 736A Aranjuez, George, 197B*, 209B Akagawa, Hiromi, 268A Araujo, Helena, 91* Akan, Ilhan, 555C Arbeitman, Michelle, 662B, 697A Akashi, Ryo, 885C Arbeitman, Michelle N., 509B Akhmetova, Katarina, 157A* Arbeláez, Pablo, 852C Akhund-Zade, Jamilla, 669C Archambault, Vincent, 796A Alberts, Bruce, Opening General Session* Arciniega, Estela, 492C Albertson, Roger, 464B, 465C Arkov, Alexey, 397A Albin, Stephanie D., 146* Armengol, Kevin, 143* Alborelli, Ilaria, 252C* Armstrong, Alissa, 353B Aldrich, John C., 65* Armstrong, Douglas, 618C, 871A Alekseyenko, Artyom, 127 Armstrong, Jennifer, 785B, 817A Aleman, Abigail, 227B Armstrong, Jennifer A., 784A Alexander, Brandy, 138, 444C Arnés, Mercedes, 558C* Alexander, Jessica L., 1* Artavanis-Tsakonas, Spyros, 97, 592A Alexander, Kuzin, 757A Arthur, Robert, 34*, 803B Alexandre, Cyrille, 96 Arya, Richa, 267C* Alfa, Ronald W., 120 Ashley, Elizabeth, 508A Alfa, Ronald Wakim, 68* Asif-Laidin, Amna, 830B* AlHaj Abed, Jumana S., 805A* Aso, Yoshi, 506B, 507C Ali, Fatima, 411C Aso, Yoshinori, 145, 505A, 534C Ali, Sara, 56 Astigarraga, Sergio, 467B, 470B Ali, Yousuf O., 159C Atallah, Joel, 651C* Aliee, Maryam, 45 Atanasov, Jenny, 822C

SPEAKER AND AUTHOR INDEX

Atanasov, Jenny E., 740B* Bayat, Vafa, 570C, 862A Athy, Derek, 36 Bayjan, Jumamurat, 368B Atsumi, Yu, 234C Baylies, Mary K., 21, 762C Avagyan, Samvel, 620B Bazinet, C., 890B Avdagic, Selma, 476B, 622A Bazinet, Chris, 371B Avidor-Reiss, Tomer, 287B Bazinet, Christopher, 374B, 387C Avila, Frank W., 401B* Bazjek, Clara, 215B Axelrod, Jeffrey, 48 Becam, Isabelle, 216C* Azanchi, Reza, 506B Beckingham, Kathleen M., 518B* Bedard, J., 890B Bedard, James E. J., 867C Beekman, Danielle, 706A, 741C* B Begun, David, 647B Begun, David J., 33 Bachtrog, Doris, 32, 127, 681C, 682A, 771C, 775A, 843C Béhague, Julien, 216C Bae, Young-Kyung, 24 Behrman, Emily, 58, 642C Baena-Lopez, Luis Alberto, 96* Behrman, Emily Louise, 452B* Bag, Indira, 790A* Bei, Danqing, 862A Bagni, Claudia, 618C Beier, Nicole L., 786C* Bainton, Roland, 512B Beirnes, Kimberly, 601A Bajgar, Adam, 135 Beitel, Greg J., 404B Baker, Bruce S., 505A Bejarano, Fernando, 827B Baker, Emily, 38 Bell, Kimberly, 742A* Baker, Lewis, 882C Bellemer, Andrew, 860B* Baker, Nicholas, 272B, 726C Bellen, Hugo, 12, 79, 570C, 585C, 588C, 772A, 880A Baker, Nicholas E., 306C, 480C Bellen, Hugo J., 862A Bakhart, Anna, 171C Beller, Mathias, 121 Balasov, Maxim, 157A, 263B* Belletier, Nicolette G., 87 Baltzley, Michael J., 539B Belloni, Giorgio, 3 Banerjee, Soumya, 487A Belozerov, Vladimir, 364A* Banerjee, Utpal, 446B Belyakova, Natalia V., 63 Banerji, Brinda, 62 Ben-David, Geulah, 379A Bao, Hongcun, 434B Bender, Welcome, 130, 800B* Bao, Xiaomin, 789C Bennett, Joan W., 566B Bao, Yuping, 456C Bennett, Kara, 602B Baonza, Antonio, 311B Benrabah, Emilie, 772A Barajas, Maria, 541A Ben-Zvi, Danny, 707B Baranski, Thomas, 67 Beppu, Kengo, 268A Barbash, Daniel A., 57 Berg, Celeste A., 195C, 200B Barber, Diane L., 123 Bergalet, Julie, 213C Barber, Glen N., 454A Bergantiños, Cora, 305B Barcelo, Gail, 254B Berger, James, 263B Bardin, Allison, 152, 435C Bergland, Alan, 642C Barikzi, Leeda, 224B* Bergland, Alan O., 58*, 669C* Baril, Caroline, 124, 236B* Bergman, Zane, 278B Barkai, Naama, 707B Bergman, Zane J., 116* Barker, Conor, 577A Berman, Gordon J., 142 Barkett, Margaret, 395B Bernstein, Sanford, 549C Barmina, Olga, 662B, 750C Bernstein, Sanford I., 550A, 620B, 624C Barnett, Austen A., 181A* Betrán, Esther, 630C, 655A Barnette, Nicole K., 876C* Bettinger, Jill, 538A Barolo, Scott, 128*, 738C Bhadra, Utpal, 269B, 790A, 832A Barrio, Lara, 70* Bhagwanji, Aayushi, 403A Barron, Daniel Allyn, 301A* Bhan, Veer, 670A* Barron, Jonathan T., 852C Bhandari, Rajan, 302B Barron, Maite, 686B Bhatt, Parag, 476B* Barros, Claudia, 883A Bhattacharya, Sharmila, 460A, 523A, 877A* Bartel, David, 27 Bhutani, Supriya, 559A* Bartholomew, Nathan R., 536B* Bi, Junfeng, 327C* Barton, Lacy J., 18* Biddulph, Taylor, 366C Bashirullah, Arash, 29, 737B Bidla, Gawa, 124 Basler, Konrad, 6, 251B, 547A, 730A Biela, Laurie M., 504C Bassuk, Alexander G., 104 Bieli, Dimitri, 743B* Bastide, Héloïse, 636C*, 667A Bier, Ethan, 140, 716B Bataillé, Laetitia, 22 Biersmith, Bridget H., 204C* Bates, Emily, 226A Bietenhader, Mailis, Plenary Session I Bauer, April, 791B* Biggin, Mark D., 852C Baumann, Aaron, 343A* Bilak, Amber, 28 Baumert, Thomas, 90 Bilder, David, 543C Bausek, Nina, 99 Bilgir, Ceyda, 74*

SPEAKER AND AUTHOR INDEX

Binari, Richard, 827B Bregere, Catherine, 502A Birdsall, Jonathan, 545B Brent, Michael, 67 Birnbaum, Morris J., 71 Brewer-Jensen, Paul, 84 Birse, Ryan Tyge, 606C* Bricker, Daniel K., 612C Bischoff, Marcus, 174C Bridges, Dave, 338B Bishop, Ruth A., 328A* Bridges, Stacey, 619A Biteau, Benoît, 441C Brill, Julie, Plenary Session I, 372C, 376A Bitterman, Moshe D., 71 Brill, Julie A., 180C Blachon, Stephanie, 287B Bristow, Chris, 756C Blackband, Steve, 851B Brittain, Andrew, 759C Blackmore, Elise, 872B Brittain, Andrew S., 652A* Blair, Seth, 300C Brock, Amanda, 310A Blair, Seth S., 225C* Brock, Amanda R., 715A* Blake, Emma, 351C Brody, Thomas, 757A, 869B Blake, Victoria, 128 Broihier, Heather, 13*, 474C, 490A, 491B Blanche, Alexandra, 827B Bronkhorst, Walter, 134 Bland, Michelle L., 71* Brooks, Alexi, 229A Blankenship, J. Todd, 158B* Brouhard, Gary, 213C Bleichert, Franziska, 263B Brown, Christopher D., 37 Bloch, Natasha, 36 Brown, Elizabeth B., 527B* Blumenstiel, Justin, 656B, 820A Brown, Emily, 775A* Blundon, Malachi A,, 88 Brown, James B., 83* Blythe, Shelby A., 26* Brown, Nicholas, 165C Bobowski, Nuala, 660C Brown, Olivia, 381C Bodmer, Rolf, Plenary Session II*, 101, 549C, 550A, 552C, 554B, Brückner, Katja, 138*, 444C* 568A, 606C Brunetti, Tonya, 749B Boehringer, Ashley, 580A, 591C Bubnys, Adele, 473B Boeke, J., 790A Buchon, Nicolas, 463A Boekel, Christian, 217A* Buckner, Michael, 856A, 857B Boerkoel, Cornelius, 601A Buenton, Dane M., 875B Boettcher, Anna-Lisa, 218B* Buhler, Jeremy, 628A Bohère, Jérôme, 244A Buhlman, Lori, 575B Bohmann, Brett, 298A Bukhanov, Sergej V., 645C Boin, Nathan, 837C Bullock, Simon, 858C Bois, Kelly E., 384C Bulyk, Martha L., 105 Boisclair Lachance, Jean-Francois, 111* Burch, Amelia M., 324C Boisclair Lachance, Jean François, 705C Burg, Deb, 878B Boivin, Antoine, 89 Burg, M., 890B Bolin, Kelsey, 270C Burg, Martin G., 878B Bollinger, Wesley, 521B Burke, Richard, 257B Bollinger, Wesley L., 243C* Burner, Kris, 537C* Bommireddy Venkata, Venu Reddy, 296B* Burnette, Miranda, 289A* Bonini, Nancy, 119 Burnouf, Sylvie, 564C Booker, Matthew, 827B Burow, Dana A., 840C* Booth, Benjamin, 79 Busby III, Theodore, 79 Borges, Rebeca, 100 Busser, B. W., 405C Börner, Jana, 871A Buti, Wisam, 256A Bortolazzo, Anthony J., 613A* Butler, Napoleon, 488B Borutska, Vasylyna, 597C Butt, Shamim A., 542B* Bosch, Justin A., 118* Buttitta, Laura, 25, 270C, 274A, 313A Botchan, Michael, 263B Bouaouina, Mohamed, 95 Boukhatmi, Hadi, 22 Bourouh, Mohammed R., 385A* C Boutros, Michael, 218B Bowlin, Kate, 61, 797B Cai, Danfeng, 198C* Bowman, Megan, 741C Cai, Weili, 386B*, 789C Bowman, Sarah K., 130* Cai, Yu, 434B Boxer, Matthew, 121 Cain, Cynthia, 723C Boyd, Brett M., 639C Cairrão, Fátima, 15 Bragdon, Meghan D., 734B Calderwood, David A., 95 Brahmachari, Vani, 807C Calero, Francisco J., 182B* Brand, Andrea, 440B, 508A Call, Gerald, 575B Brankatschk, Marko, 191B Call, Gerald B., 500B, 536B Branski-Arieli, Merav, 707B Callaerts, Patrick, 562A, 618C Braukmann, Carina, 193A* Callier, Viviane, 329B Braun, Bremen, 869B Cammarato, Anthony, 549C Brazill, Jennifer M., 159C* Campbell, Jacob B., 329B* Brech, Andreas, 8 Campo, Daniel, 462C, 509B, 640A, 697A, 770B Breese, Rebecca, 488B Campusano, Jorge M., 526A

SPEAKER AND AUTHOR INDEX

Cannon, Leah, 549C* Chen, Jing, 845B Cao, Jinshuai, 727A Chen, Jonathan, 289A Cao, Min, 151 Chen, Jung Hsuan, 431B Cao, Xu, 119 Chen, Kai, 108 Cao, Yang, 560B* Chen, Kevin, 742A Cao, Yufang, 194B Chen, Kuchuan, 12 Caporilli, Simona, 383B, 850A Chen, Michael, 580A, 591C Card, Gwyneth, 871A Chen, Nan, 534C* Card, Samantha, 84 Chen, Qichuan, 256A, 712A Cardona, Albert, 483C Chen, Rui, 862A Cardoso, Maira, 91 Chen, Shann-Ching, 198C Carmon, Amber, 842B* Chen, Weitao, 41* Caroti, Francesca, 653B*, 657C Chen, Wen-Feng, 431B Carpinteyro Ponce, Javier, 654C* Chen, Xi, 412A* Carpinteyro-Ponce, Javier, 643A Chen, Xiang, 52 Carrell, Sophia, 704B* Chen, Xin, Plenary Session I* Carte, Adam N., 734B* Chen, Yan, 532A* Carthew, Richard, 111 Chen, Yi-Jiun, 201C Casagranda, Franca, 418A Chen, Z., 398B Casas-Tinto, Sergio, 290B* Chen, Zhihua, 593B Casas-Tintó, Sergio, 558C Cheng, Annie, 584B Casper, Sarah, 477C* Cheng, Chu-Ya, 826A* Cassel, Joel, 102 Cheng, MeiHsin, 781A* Castanieto, Angela, 154* Cheng, Su-Wen, 261C Cavalli, Giacomo, 60*, 811A Cheng, Yim Ling, 23* Celik-Fuss, Arzu, 479B Cheng, Yuzhong, 745A*, 808A Celniker, Susan, 109 Chernyk, Yaroslava, 597C Celniker modENCODE Transcription Consortium, 83 Cherry, Sara, 133 Ceresa, Gabriella, 541A Cherry, Smita, 503B, 540C Cérézo, Delphine, 40 Chesnokov, Igor, 157A, 263B Cetera, Maureen P., 199A* Cheung, Philip, 868A Chabu, Chiswili, 548B Chhabria, Raveena M., 623B Chahal, Arjun, 418A Chhiba, Lea, 769A Chakrabandhu, Krittalak, 6 Chi, Wanhao, 53 Chambers, Moria C., 461B* Chia-Kang, Tsao, 486C* Chan, Chih-Chiang, 503B, 540C Chiang, Wei, 196A Chan, Robin, 538A Chihara, Takahiro, 484A Chan, Sarah, 622A Chiolo, Irene, 61*, 792C, 797B Chandran, Rachana R., 488B Chiu, Joanna, 510C, 647B Chang, Ching-Ho, 665B Cho, Aeri, 160A* Chang, Henry, 235A Cho, Bomsoo, 48 Chang, Howard, 592A Cho, Dong-Yeon, 863B Chang, Karen, 502A* Cho, Kyoung Sang, 601A Chang, Karen T., 586A Cho, Yueh, 421A Chang, Kung-Yen, 834C Chobanyan, Tamar, 592A Chang, Peter, 697A Choesmel-Cadamuro, Valerie, 198C Chang, Peter L., 509B Choi, Jae Young, 637A* Chang, Tiffany, 194B, 617B Choi, Kunho, 601A Chang, Yen-Ching, 485B* Choi, Sekyu, 72* Chang, Yu-Wei, 196A Chougule, Ashish B., 161B* Chanut-Delalande, Helene, 244A* Christensen, Tim, 265A Charles, Jean-Philippe, 346A Christensen, Tim W., 264C Charng, Wu-Lin, 862A Chtarbanova-Rudlof, Stanislava, 560B Chaston, John, 56* Chu, Tin-Chun, 370A Chatterjee, Nabanita, 100 Chu, Xiowen, 74 Chaubal, Ashlesha M., 787A* Chung, Brian Y., 318C, 344B* Chaudhuri, Anathbandhu, 496A* Chung, Jongkyeong, 72 Chaung, Monica, 872B Chung, Phuong, 146 Chechenova, Maria, 744C* Chung, Phuong M., 80 Chen, Chao-Yi, 825C* Chung, Se-Yeon, 407B* Chen, Chun-Hong, 825C, 826A Chun-Hong, Chen, 607A Chen, Chun-Kan, 502A Cicek, Omer, 352A* Chen, Dahong, 482B* Cisneros, Marilyn, 724A Chen, Dongsheng, 593B Civetta, Alberto, 660C Chen, Elizabeth, 50 Clanton, Joshua, 203B Chen, Hsi-Ju, 825C Claridge-Chang, Adam, 883A Chen, Hui-Min, 78*, 343A, 858C Clark, Alvin J., 872B Chen, Jessica Y., 462C Clark, Andrew G., 57 Chen, Jia, 756C Clark, Rebecca, 98* Chen, Jieyan, 2*, 286A* Clark, Sarah G., 471C*

SPEAKER AND AUTHOR INDEX

Claudius, Ann-Katrin, 345C* Dalton, Justin E., 509B Cléard, Fabienne, Plenary Session II Damrath, John, 274A Cleary, Michael, 840C Daniel, Emeline, 853A Clemens, James, 235A Daniel, Scott G., 847A* Clough, E., 398B Daniels, Karla, 706A Clough, Emily, 399C Danuser, Gaudenz, 198C Cloutier, Marissa, 464B* Dao, Anh, 297C Cochrane, Veronica A., 55, 679A Dardhalon-Cuménal, Delphine, 806B Cochrane, Wes G., 679A Das, Aniruddha, 559A Cochrane, Wesley G., 55* Das, Arunika, 280A* Coelho, Ana V., 15 Das, Devika, 797B Coelho, Dina S., 15* Das, Nilanjana, 260B Coffman, Scarlett, 538A Das, Rahul, 357C*, 362B Colaianni, Ryan, 557B Das, Raibatak, 207C, 208A Cole, Robert, 353B Das, Shradha, 183C* Colmenares, Serafin, 798C Das, Sudeshna, 256A, 712A Colmenares, Serafin U., 792C* Dasari, Vasanthi, 807C Colombani, Julien, 6* Datta, Rhea R., 105* Colombo, Maria, 316A David, Rand, 342C Colosimo, Christina M., 500B* Davidson, Andrea, 611B Colotti, Gianni, 3 Davies, Daphne, 383B Colquhoun, Jennifer, 378C Davis, Cara, 488B Combs, Peter A., 861C* Davis, Spicie M., 539B Comeron, Josep, 626B De, Nabanita, 834C Consoulas, Christos, 492C De, Sandip, 808A Cook, Cyril, 298A Deady, Lylah, 414C Cook, John, 769A DeAguero, Ashley A., 724A* Cook, Kevin R., 881B Dean, Hunter, 456C Cool, Jonah, 402C* Deaton, Aimee M., 130 Cooley, Lynn, 114, 170B, 390C Debat, Vincent, 806B Coombs, Daniel, 207C, 208A Debrunner, Marc, 251B Coombs, Rachel, 177C Dekanty, Andrés, 70 Cooper, Brandon S., 692B* Delabaere, Laetitia, 66* Corona, Davide, 818B* Delest, Anna, 811A Correia, Andreia, 250A Delmarre, Valérie, 89 Corrigan, Laura, 117 Delohyt, Jacquie, 538A Cortez, Carla, 224B De Luca, Maria, 671B, 833B Costa, Marta, 871A DeLuca, Steven Z., Plenary Session II Costes, Sylvain, 798C DeLuca, Todd, 827B Couble, Pierre, 66 Deng, Wu-Min, 389B Coughlin, Maura, 723C* Dent, Lucas G., 92* Court, Robert, 871A Deobagkar, Deepti D., 819C* Coutelis, Jean-Baptiste, 40 DePace, Angela, 865A Cox, Daniel N., 143, 471C, 472A DePace, Angela H., 107, 734B Cox, Sarah, 31 Dermaut, Bart, 562A* Coyne, Alyssa, 102* DeSalvo, Michael, 512B Cozart, E. J., 405C Deshpande, Nikita, 776B* Cranston, Katie, 104 de Vanssay, Augustin, 89 Cripps, Richard, 220A, 744C, 749B Devergne, Olivier, 254B* Cripps, Richard M., 724A, 755B, 758B De Vito, Scott, 705C* Criscoe, Dallas, 698B* DeVorkin, Lindsay, 273C Crocker, Amanda J., 528C* Dew-Budd, Kelly, 594C* Crocker, Justin, 746B* Dew-Budd, Kelly J., 668B Croote, Denise, 351C Dhaliwal, Rajdeep, 385A Crosby, Madeline, 767B*, 774C Dhanaswar, Arida, 706A Crowther, Damian, 572B Diaconeasa, Bianca, 595A Cruz Moreno, Beatriz, 140 Dialynas, George, 610A Cunningham, Courtney, 496A DiAngelo, J., 890B Cutler, Timothy L., 561C* DiAngelo, Justin, 522C Czerniecki, Stefan, 207C, 208A DiAngelo, Justin R., 337A, 354C, 844A DiAntonio, Aaron, Plenary Session II* Diao, Feici, 515B Diaz-Garcia, Sandra, 311B* D Diaz Torres, Alfonsa, 416B* Dib, Azza, 244A Daempfling, Lea, 747C* Dickinson, Michael, 871A Dahal, Giri Raj, 226A* Dickman, Dion, 502A Dahmann, Christian, 45 Diehl, Jonathan, 510C Dale, R., 398B Dillman, Adler R., 103*, 453C* Dale, Ryan K., 802A Dimitriadou, Agapi, 492C

SPEAKER AND AUTHOR INDEX

Dimlich, Douglas, 592A Ekaterina, Sivoplyas, 627C* DiNardo, Stephen, 173B Eksi, Ece, 719B Ding, Jiyuan, 854B Elgin, S., 890B* Diop, Soda, 101* Elgin, Sarah, 628A*, 791B Do, David, 613A Elgin, Sarah C. R., 793A*, 891C Do, Trieu, 420C Elliot, Chas, 106 Dobens, Leonard, 357C, 362B Ellis, Stephanie, 206B Dobens, Leonard L., 291C* Ellis, Stephanie J., 95, 205A* Dobi, Krista C., 762C* Ellison, Chris, 127 Dobson, Adam, 56 Emmert, David, 767B, 774C Docherty, James E., 337A* Enard, David, 669C Doe, Chris Q., 150 Erb, Michael A., 784A* Dolezal, Tomas, 135*, 303C Erives, Albert, 42*, 652A, 706A, 741C, 759C Dolgikh, Elena, 512B Erro Go, Nancy, 273C Dollar, Gretchen, 181A Erwin, Alex, 820A Dolma, Kunsang, 164B Esquivel, Cecilia, 259A Dols, Jacqueline, 564C Esquivel, Mario, 123 Domanitskaya, Elena, 409A Estes, Patricia, 102 Dombert, Luke, 237C* Estes, Patricia A., 488B* Domingos, Pedro M., 15 Estrada, Beatriz, 174C Domingues, Heber, 130 Etchegarary, Jon Iker, 30 Domingues, Susana, 655A* Evans, Cory, 446B Donner, Julia, 351C Evans, Genevieve E., 529A Donovan, Will, 100 Evans, Tim, 468C* Donti, Taraka, 12 Eveland, Matthew John, 671B* dos Santos, Gil, 767B, 774C Dottermusch-Heidel, Christine, 193A Doublesex Consortium, 399C Douglas, Angela, 56, 339C F Dourlen, Pierre, 562A Douthit, Jessica, 467B* Fabian, Lacramioara, 180C, 372C*, 376A Dresch, Jacqueline, 748A Fabian, Lacramiora, Plenary Session I Drescher, Brandon, 712A Faculty & Students of the Genomics Education Partnership, 628A Drewell, Robert, 748A* Fairchild, Michael, 373A* Dronska, Chrystyna, 597C Fairchild, Michael J., 95, 199A Droste, Andrew, 406A Fallah, Tara, 487A Drummond-Barbosa, Daniela, 156, 353B, 384C Falls, Kathleen, 767B, 774C Du, Wei, 53 Fan, Frances, 614B* Dubé, Alison, 867C* Fan, Shih-Jung, 117 Dubnau, Joshua T., 100* Fang, Shu, 665B Dubreuil, Ron, 595A* Fang, Yanshan, 119* Duch, Carsten, 492C, 871A Farag, Mena, 489C* Ducuing, Antoine, 253A Farhat, Maira, 722B Dudek, Karrie D., 509B Fassler, Jan, 706A Duggan, Shannon, 35, 648C, 650B Fear, Justin, 697A Duneau, David, 699C* Fear, Justin M., 509B Dunn, Joshua G., 87* Fedina, Tatyana Y., 358A* Dupont, Camille, 806B* Feiber, Amy, 846C Dupont, Cloé, 562A Feng, James, 206B Duque, Thyago S. P. C., 663C Fenger, Douglas D., 868A* Duran, Brittany, 162C* Ferguson, Scott B., 88*, 388A, 875B Dushay, Mitch, 215B Fernandes, Joyce, 317B, 487A Dworkin, Ian, 660C Fernandez-Funez, Pedro, 122*, 582C, 851B* Dzeyk, Kristina, 27 Fernandez-Gonzalez, Rodrigo, 113, 210C Ferrus, Alberto, 290B Ferrús, Alberto, 558C E Feschotte, Cedric, 630C Fieger, Naomi, 613A Figueroa-Clarevega, Alejandra, 543C* Eaton, Suzanne R., 191B Filipp, Fabian, 606C Eckstrand, Erica, 655A Fink, Jill, 67 Edeleva, Evgeniia V., 605B* Finley, Kim, 330C* Edgar, Bruce, 437B, 443B, 546C Finley, Kim D., 624C Ehaideb, Salleh, 104* Fischer, Kathrin, 838A Eichenlaub, Teresa, 218B Fisher, Jasmin, 107 Eichhorn, Stephen, 27 Fisher, William, 109 Eikenes, Asmund H., 8* Flegel, Kerry, 270C* Eisen, Michael, 682A, 683B, 754A, 835A Fletcher, Alexander, 275B Eisen, Michael B., 319A, 696C, 861C Flockhart, Ian, 856A Eivers, Edward, 227B* Flockhart, Ian T., 855C*, 857B

SPEAKER AND AUTHOR INDEX

FlyBase Consortium, 767B, 774C Gardner, Eugene, 841A Foley, Andrew, 223A Garlapow, Megan, 519C* Foley, Brad R., 511A* Garlena, Rebecca, 240C, 882C Folker, Eric S., 21 Garrett, Rebecca, 302B Fonetenele, Marcio, 91 Gates, Julie, 162C, 163A, 169A Fonseca, Andreia, 592A Gavalda, Arnau, 111 Foo, Catherine K., 87 Gavis, Elizabeth, 475A Foo, Sun Melody, 108* Gavis, Elizabeth R., 87 Foos, Marianna, 855C Gavory, Gwenaelle, 124* Ford, Audrey, 613A Gbur, Samantha C., 404B Forés, Marta, 736A Ge, Yawei, 695B Forstall, John, 712A Gebelein, Brian, 751A Förster, Dominique, 85 Geisbrecht, Erika, 51, 215B Fountain, Matthew A., 88 Geisbrecht, Erika R., 204C Franc, Nathalie C., 449B Gelbart, William, 767B, 774C Franz, Rachel, 163A* Géminard, Charles, 40 Frappaolo, Anna, 3 Gendron, Christi M., 318C Frasch, Manfred, 22 Gerard, Jessica L., 382A Freeman, Jessica, 275B Gérard, Pierre, 777C Fregoso Lomas, Mariana, 705C Gerber, Céline, 891C Freibaum, Brian, 102 Gergen, John Peter, 752B Fremin, Brayon, 749B* Gergen, J. Peter, 742A French, Rachael, 613A Gershman, Brett W., 768C* Frendo, Jean-Louis, 22 Getzy, Michael D., 504C Freyer, Laina, 306C* Geyer, Pamela K., 18 Friedman, Daniel, 662B, 750C* Ghasemi, Mohsen, 807C* Friedman, Jeramey, 704B Ghosh, Sushmita, 769A*, 845B, 846C Frise, Erwin, 109* Giansanti, Maria Grazia, 3* Frizzell, Kimberly, 38 Gibbs, Allen, 521B Fuenzalida-Uribe, Nicolás, 526A* Gibilisco, Lauren, 843C* Fujii, Shinsuke, 533B Gibson, Hayley, 487A Fujimoto, Koichi, 308B Giedt, Michelle, 365B* Fujioka, Miki, 801C* Gilchrist, Ashley A., 638B* Fujita, Naonobu, 190A* Gilliland, William D., 392B Fulga, Tudor A., 827B Gilly, Quentin, 857B Fulkerson, Eric, 488B Gingras, Robert M., 844A Fuller, Margaret T., 3 Giniger, Edward, 112, 587B Fuller, Zach, 35* Girton, Jack, 258C, 279C, 789C, 796A Fuller, Zachary, 648C Gistelinck, Marc, 562A Futran, Alan, 94 Gitler, Aaron, 102 Glassford, William, 106 Gligorov, Dragan, 191B Gloss, Andrew, 687C* G Goberdhan, Deborah, 117 Godt, Dorothea, 412A Gabrawy, Mariann M., 615C* Gohl, Daryl, 743B Gabrielian, Jessica, 770B Golden, Krista, 274A Gabrielian, Jessica I., 462C* Golding, Ido, 110 Gafni, Aviv, 418A Golovnina, Kseniya, 121* Gajan, Ambikai, 787A Gombos, Rita, 469A* Galdos, Mauricio, 820A* Gonsalvez, Graydon, 192C Galetti, Sandrine, Plenary Session II Gonzales, Josefa, 58 Galko, Michael J., 143 Gonzalez, Arysa, 330C Gall, Joseph, 841A Gonzalez, Inmaculada, 60 Gallio, Marco, 535A Gonzalez, Jacob M., 417C* Gallop, Jenny, 165C Gonzalez, Josefa, 686B*, 886A* Gama Carvalho, Margarida, 592A González-Crespo, Sergio, 736A Gandhi, Kevin, 118 Gonzalez-Morales, Nicanor, 40 Gandy, Carina, 117 Gonzalez Reyes, Acaimo, 416B Ganetzky, Barry, 560B, 621C Goodman, Alan G., 454A* Gangaraju, Vamsi, 377B Goodwin, Katharine, 206B* Gangloff, Steven J., 875B Goodwin, Katie, 205A Ganter, Geoffrey K., 514A, 516C Goodwin, M., 398B Gantz, Valentino M., 716B* Goodwin, S., 398B Gany, Agnes, 418A Goodwin, Stephen, 508A Gao, Jie, 584B Gopalan, Venkat, 86 Gao, Ming, 397A* Gorchakov, Andrey, 127 Garcia, Caroline A., 384C Gordesky-Gold, Beth, 133 Garcia, Kristine, 567C, 714C Gordon, Hannah B., 563B* Gardel, Margaret L., 199A Gorfinkiel, Nicole, 167B

SPEAKER AND AUTHOR INDEX

Gormley, Andrew, 601A Haltom, Amanda, 201C* Gorski, Sharon M., 273C* Hamaratoglu-Dion, Fisun, 743B Gorsky, Marianna K., 564C* Hamm, Danielle C., 132 Gosavi, Ujwala, 371B Hammer, Kenneth, 423C* Gosavi, Ujwala Ashok, 374B* Hammonds, Ann, 109 Gottron, Melissa, 147 Hamp, Julia, 193A Goult, Benjamin T., 95 Han, Jackie, 480C Gourhand, Vanessa, 216C Han, Zhe, 194B*, 617B*, 827B Govind, Shubha, 459C Hand, Steven C., 329B Grabowska, Dorota B., 375C* Hang, Saiyu, 140 Graham, Brett, 12, 570C Hanlon, Caitlin D., 410B* Grainger, Lindsay, 317B Hanna, Giovanni, 643A Gramates, Sian, 767B, 774C Hansen, Timothy, 565A* Gratz, Scott J., 75 Hanzlick-Burton, Camden, 887B Graybeal, Lacey, 472A* Hara, Yusuke, 268A Graze, Rita M., 639C* Harbison, Susan, 673A Grbac, Daniel, 149 Hardy, Christopher, 247A Green, Nicole, 51, 215B* Hariharan, Iswar, 7, 363C Greenberg, Anthony, 672C* Hariharan, Iswar K., 118, 315C Greenspan, Leah J., 422B* Harney, Rachel, 706A*, 741C Greer, Christina, 728B Harris, Devon E., 382A Greer, Lee F., 629B* Harris, Greg L., 554B Gregor, Thomas, 732C Harris, Robin, 363C* Griggs, Ellen, 270C Harris, Shane A., 350B Grillo-Hill, Bree K., 123* Harrison, Chris, 820A Grönke, Sebastian, 564C Harrison, Douglas, 365B Grossman, Rona, 736A Harrison, Jon F., 329B, 366C* Grotewiel, Mike, 538A* Harrison, Melissa, 754A Groth, Verena, 193A Harrison, Melissa M., 132 Grushko, Olga, 270C, 313A Hart, Michael, 102 G. Tapadia, Madhu, 625A Hartenstein, Volker, 483C* Gu, Joy, 112 Hartl, Marion, 520A* Gu, Tingting, 793A Harvanek, Zachary M., 318C* Guan, Georgia, 142 Harvey, Beth, 201C Gubb, David, 104 Harvey, Kieran F., 92 Guenther, Maximilian N., 81* Hasan, Gaiti, 524B Guichard, Annabel E., 140* Hasan, Salman, 424A* Guio, Lain, 686B Hashimoto, Yoshiko, 244A Gunawardena, Shermali, 565A Haskel-Ittah, Michal, 707B* Gunawardena, Shermali D., 164B*, 212B* Hasper, John W., 388A* Guo, Linlin, 455B* Hastert, Mary Catherine, 161B Guo, Zhihao, 385A Hateley, Shannon, 835A* Gupta, Alind, 376A* Hatfield, Isabelle, 338B* Gupta, Paromita, 387C* Hatori, Ryo, 230B Gushiken, Takuma, 230B* Hauling, Thomas, 458B Gutierrez, Gabriel, 497B Hayes, Mike, 706A Gutzwiller, Lisa M., 751A* Haynes, Gwilym, 35, 648C* Gyuricza, Mercedes R., 281B* Haywood, Robert, 891C He, Li, 198C, 245B He, Qiye, 129 He, Xiaofang, 529A* H He, Yuchun, 79 Heberlein, Ulrike, 146, 506B HA, Tal Soo, 481A Heidari, Raheleh, 553A Hadjieconomou, Dafni, 520A Heinrich, Stephanie, 366C Haelterman, Nele, 585C, 588C Helleu, Quentin, 665B, 777C* Haelterman, Nele A., 862A* Hemmer, Lucas, 656B* Hafirassou, Mohamed Lamine, 90 Hempel, L., 398B Hage, Anthony, 878B* Henderson, Benjamin W., 456C* Haglund, Kaisa, 8 Henstridge, Michelle A., 39* Hahn, Matthew, 688A Herman, Tory, 477C Hainz, Kelly, 622A Hermant, Catherine, 89* Hákonardóttir, Guðlaug Katrín, 208A Hernandez, Ana, 326B Hakonardottir, Gudlaug K., 207C* Hernandez, Giovanna, 488B Hales, Karen G., 381C, 382A Hernandez, Steven, 371B Halfon, Marc S., 762C Herrera Reyes, Alejandra, 208A Hall, Marleshia Dorcell, 616A* Hetie, Phylis, 422B Hall, Sonia, 255C*, 887B* Hétié, Phylis, 424A Halme, Adrian, 297C, 302B* Hetzer, Martin, 402C Haltiwanger, Robert, 201C Hewes, Randall, 482B

SPEAKER AND AUTHOR INDEX

Hewitt, Matt, 538A Hultmark, Dan, 448A, 450C Hiesinger, Peter Robin, 10 Humphreys, Gregory B., 228C Hiesinger, Robin, 503B, 540C Hundertmark, Tim, 735C Higgins, Michael L., 752B* Hung, Ko-Hsuan, 731B Highfill, Chad A., 54* Hunter, Miranda V., 113* Hill, Ron, 346A Huynh, Megan, 580A, 591C Hiller, Mark, 723C Hwang, Richard, 525C Hilliker, Arthur, 364A Hwang, Yihharn, 381C Hime, Gary R., 418A* Hwangbo, Dae-sung, 438C Hindes, Danielle E., 88 Hindle, Samantha, 512B* Hirschman, Leah, 723C Ho, Diana M., 97* I Ho, Eric Tatt Wei, 864C Hoekstra, Luke A., 331A* Iacobucci, Gary, 164B Hofmann, Line, 216C Igaki, Tatsushi, 294C, 308B Holden, Nicole, 366C Igiesuorobo, Oghomwen, 478A Holderbaum, Laura, 856A Ignatyeva, Maria A., 63 Holloway, David M., 44, 763A* Ihry, Robert, 737B Holmbeck, Marissa, 335B Iiduka, Ryo, 268A Holmbeck, Marissa A., 332B* Ilsley, Garth, 746B Holmgren, Robert, 216C Ilsley, Garth R., 107* Holt, Elliott, 278B* Imano, Takao, 288C Holub, Natalia, 597C* Imhof, Alex, 61 Homberg, Melanie, 838A Imhof, Axel, 790A, 792C Hong, Yang, 201C Imler, Jean-Luc, 90 Honjo, Ken, 147 Inamdar, Arati A., 566B* Hoover, Kendall, 13, 490A* Indelicato, Claire-Emmanuelle, 367A Hopfen, Corinna, 359B* Inoue, Yoshiko, 165C* Hopkins, Lucas, 265A Irvine, Ken, 296B Hopp, Hannah, 61 Irwin, Madison N., 567C* Horabin, Jamila, 812B Isabella, Adam J., 20* Horard, Béatrice, 66 Ishimoto, Hiroshi, 512B Hori, Aki, 451A, 457A* Ishio, Akira, 232A Horne-Badovinac, Sally, 20, 199A Israel, Lars, 61 Horng-Dar, Wang, 607A Ivey, Lauren, 381C Hosamani, Ravikumar, 523A*, 877A Iyengar, Atulya, 104 Hoskin, Roger, 79 Iyer, Eswar P. R., 143, 472A Hou, Claire, 273C Iyer, Srividya C., 143, 471C, 472A Hou, Steven, 436A* Housden, Ben, 766A Housden, Benjamin E., 856A*, 857B Howard, Austin, 403A* J Howick, Virgina, 452B Howick, Virginia1 M., 59 Hsiao-Yen, Chan, 607A* Ja, William, 136 Hsieh, Cheng-Wen, 540C Jacinto, Antonio, 312C* Hsieh, Emily, 38 Jackson, F. Rob, 144 Hsiung, Frank, 873C Jackson, Megan, 166A* Hsu, Hwei-Jan, 421A Jacobsen, Thomas, 874A Hsu, Ju-Yin, 462C Jacobson, Matt, 512B Hsu, Ta-Hsing, 415A* Jafar-Nejad, Hamed, 201C, 231C Hu, Yanhui, 69, 855C, 856A, 857B Jagge, Christopher, 533B Hua, Brian, 821B* Jagla, Krzysztof, 153*, 721A Huang, D., 405C Jagla, Teresa, 721A* Huang, Hai, 93, 717C* Jahanshahi, Atousa, 650B Huang, Haixia, 825C Jain, Shruti, 807C Huang, Jiuhong, 245B* Jaiswal, Manish, 12, 570C, 585C, 588C, 862A Huang, Lawrence, 459C James, Anna, 500B Huang, Wilson, 190A James, Rebecca, 13, 490A Huang, Xun, 327C James, Taylor A., 539B* Huang, Yan, 601A Jana, Nihar, 559A Huang, Yanmei, 144* Jangam, Diwash, 630C* Huang, Zhenxing, 434B Jansen, Marlon, 584B Hubickey, Joana, 596B Janssen, Aniek, 794B* Hudson, Andrew, 114*, 170B Janssens, Derek, 149 Hueber, Anne-Odile, 6 Jarnigan, Julie, 611B Hueston, Catherine, 9 Jarrar, Hilal, 613A Hughes, Kimberly A., 73 Jarvis, Beth, 255C Huijbregts, Richard, 157A Jasper, Heinrich, 249C, 438C, 439A, 441C, 455B

SPEAKER AND AUTHOR INDEX

Jaszczak, Jacob, 297C* Kajla, Babita, 700A* Jayaswal, Vivek, 703A Kakrecha, Bijal C., 844A* Jaynes, James B., 801C Kalvakuri, Sreehari, 550A*, 568A* Jean, Steve, 31* Kanakousaki, Kiriaki, 313A* Jeffries, N., 405C Kanca, Oguz, 743B Jegga, Anil G., 527B Kańdula, MM, 859A Jemc, Jennifer C., 406A* Kane, Eric, 223A Jenkins, Victoria Kathryn, 271A* Kanellopoulos, Alexandros, 618C* Jenny, Andreas, 181A Kang, Jin Joo, 731B Jermusyk, Ashley Ann, 43* Kang, Yunsik, 29* Jezek, Addison E., 598A* Kango-Singh, Madhuri, 276C, 304A, 309C, 544A, 561C, 567C, Jha, Aashish R., 37* 604A, 713B, 714C Jia, Dongyu, 389B* Kannan, Ramakrishnan, 112* Jian-Chiuan, Li, 607A Kao, Joyce L., 509B Jiang, Huaqi, 151* Kao, Joyce Y., 640A*, 680B*, 879C* Jiang, Jianqiao, 850A Kao, Shih-Han, 421A Jiang, Lan, 488B Kaplan, Tommy, 754A Jiang, Lichun, 862A Karch, François, 191B Jiang, Pengyao, 764B* Karch, Francois, Plenary Session II* Jimenez, E., 398B* Karpac, Jason, 455B Jiménez, Gerardo, 736A* Karpen, Gary, 792C, 794B, 798C Jin, Jennifer, 503B, 540C Karpen, Gary H., 61, 778A, 786C, 795C Jin, Yinhua, 437B* Karuppudurai, Thangavel, 535A Jindra, Marek, 345C, 346A* Kassis, Judith, 745A Joazeiro, Claudio, 568A Kassis, Judith A., 808A* Johanning, Evan, 636C Katoh, Toshiko, 16 Johansen, Jorgen, 258C, 279C*, 789C, 796A Katzman, Charles, 128 Johansen, Kristen, 258C, 279C, 789C, 796A Kaufman, Ronit, 390C* John, Ciny, 517A* Kaufman, Thom C., 881B Johndreau, Kristin, 602B Kaun, Karla, 506B Johnson, Aaron N., 837C* Kaun, Karla R., 146 Johnson, Dorothy M., 408C* Kearse, Michael, 378C Johnson, Jennifer, 725B* Kearse, Michael G., 768C Johnson, Karyn, 277A Kee, Yee, 50 Johnson, Travis K., 39, 708C* Keebaugh, Erin, 698B Johnson, Winslow, 106 Keene, Alex, 141, 243C, 507C, 521B* Johnston, Jeff, 129, 729C Keene, Alex C., 522C Johnston, Jeffrey, 788B Keita, Nakia, 591C Johnston, Laura A., 305B Kelley, Colleen, 855C, 856A Johnston, Robert J., 131* Kellis, Manolis, 756C Johnston, Shelby, 403A Kelpsch, Daniel, 52 Jonatova, Lucie, 135, 303C* Kempf, Edward, 517A Jones, C., 890B Kendall, Natalie, 497B Jones, D. Leanne, 440B Kennedy, Cameron, 792C Jones, Leanne, 402C Kennison, James A., 809B* Jones, Rick, 805A Keränen, Soile V. E., 852C* Joseph, Antony, 109 Kern, Andrew D., 644B, 688A*, 691A Joshi, Sonal S., 814A* Keshishyan, Tatevik, 267C Jourjine, Nicholas, 695B Khalil, Sarah, 461B Joyce, Eric, 282C*, 816C Khan, Mehnaz A., 615C Juarez, Matthew, 227B Khan, Mohammad, 323B Jud, Molly C., 246C* Khan, Sumbul Jawed, 310A, 314B* Juengling, Antje, 838A* Khare, Swati, 122 Jülicher, Frank, 45 Khire, Atul, 287B* Julien, Anais, 100 Kieffer, Matthew B., 596B* Jung, Wei-Hung, 503B* Kiger, Amy, 31, 176B, 190A Jurado-Gomez, Jaime, 167B* Kim, Charlie, 11 Juriscova, Andrea, Plenary Session I Kim, Geon Ho, 339C* Kim, Grace E. S., 120 Kim, Ji Hoon, 50* Kim, Jihyun, 438C* K Kim, Seung K., 68, 120 Kim, Sharon, 785B* Kadlec, L., 890B Kim, Y., 398B Kadlec, Lisa, 237C Kim, Yoon-Joon, 243C Kadrmas, Julie L., 168C* Kim, Young-Jun, 478A Kageyama, Yugi, 244A King, Felicia, 669C Kahn, Tatyana, 810C King, Matthew R., 802A Kai, Toshie, 831C King-Jones, Kirst, 347B, 349A Kaiser, Vera, 127 Kingston, Robert E., 130

SPEAKER AND AUTHOR INDEX

Kino, Yoshihiro, 559A Kulikov, Alexey, 635B Kirkland, Cassandra, 660C Kumar, Justin, 760A Kitamoto, Toshi, 497B Kumar, Satish, 399C* Kitamoto, Toshihiro, 512B Kumar, Sudhir, 866B, 869B Kitapci, Tevfik H., 770B* Kunitake, Ryan, 61 Kitapci, Tevfik Hamdi, 509B Kunttas-Tatli, Ezgi, 219C* Kitapci, Tevik Hamdi, 697A Kuntz, Steven G., 319A* Kitay, Brandon M., 159C, 454A Kupinski, Adam P., 217A Kitzman, Jacob, 38 Kuraishi, Takayuki, 451A*, 457A Klaus, Angela V., 370A Kurata, Jessica, 748A Klawiter, Agnieszka, 765C* Kurata, Shoichiro, 451A, 457A Kleinsorge, Sarah, 187A Kurkciyan, Adrianne, 140 Kleinsorge, Sarah E., 184A* Kurswe, Jochen, 275B Klomp, Jeff, 36* Kurthkoti, Krishna, 834C Knapp, Jon-Michael, 80*, 146 Kurzhals, Rebeccah, 822C* Knee, Jose M., 322A Kuzina, Irina, 112 Knowles, David W., 852C Kwan, Chun Wai, 36, 709A* Knust, Elisabeth, 183C, 185B, 188B Kwon, Hailey J., 304A* Kockel, Lutz, 68, 120 Koenecke, Nina, 788B* Koestler, Stefan A., 479B* Koh, Michele, 351C L Kohl, Kathryn P., 266B Kokuryo, Akihiko, 288C Labdik, Ashley M., 608B* Kolahgar, Golnar, 445A*, 447C Lack, Justin, 636C Kolotuev, Irina, 115 Lack, Justin B., 641B* Kolotueva, Irina, 853A* LaFlamme, Brooke A., 401B, 513C Komori, Hideyuki, 149, 432C* Lai, Eric C., 827B Kondo, Shu, 76* Lai, Lien, 86 Konev, Alexander, 779B Lai, Sen-Lin, 150* Konev, Alexander Y., 63* Lam, Joanne, 883A Konikoff, Charlotte E., 869B* Lam, Vu, 510C* Konno, Hiroyasu, 454A Lamba, Deepak, 249C Konno, Keiko, 454A Lambhod, Chanderkala, 701B* Kopp, Artyom, 651C, 659B, 662B, 677B, 750C Lamkemeyer, Tobias, 345C Korff, Wyatt, 534C, 871A* Lan, Qing, 151 Kornberg, Thomas, 41, 711C, 717C Landry, Christian, 143 Kornberg, Thomas B., 93, 873C Landy, Kathryn B., 281B Kotzebue, Roxanne, 330C Lang, Michael, 684C* Kowanda, Michelle, 839B Langbein, Lauren, 848B Kowanda, Michelle A., 213C* Langen, Marion, 10 Kozhevnikova, Elena, 823A Langlands, Alistair, 197B Kraft, Karoline F., 433A* Langley, Charles H., 778A, 795C* Kraft, Robert, 872B Langley, Sasha, 792C Kramer, Helmut, 498C Langley, Sasha A., 778A* Krämer, Helmut, 259A, 501C Langley, Sasha A,, 795C Kramer, Jamie, 134 Lantz, Kathryn, 247A* Krantz, David, 497B Lapoint, Richard, 631A*, 687C Krauchunas, Amber, 396C LaRocque, Jan, 794B Krautz, Robert, 458B* Larschan, Erica, 725B, 815B Krawchuk, Kristopher, 237C Larschan, Erica N., Plenary Session I* Kreil, DP, 859A Larsen, Camilla, 489C Kreitman, Martin, 37, 764B LaRue, Kelly M., 142* Krijgsveld, Jeroen, 27 Lasebny, Oleg, 635B Krishnan, Badri, 283A* Lasko, Paul, 213C, 577A, 839B Krishnan, Jaya, 64* Latapie, Yvan, 244A Krishnan, Natraj, 496A Latham, Kristin L., 539B Kronhamn, Jesper, 450C Latino, Michelle, 238A Kronja, Iva, 27* Lawal, Hakeem, 497B* Krotzer, Mary Jane, 496A Lawrence, Austie F., 388A Krueger, Sabrina, 753C* Laws, Kaitlin, 156*, 353B Krug, Lisa, 100 Layne, John E., 527B Ku, Hsueh-Yen, 377B* Lazzaro, Brian, 452B, 463A, 699C Kuang, Chaoyuan, 274A Lazzaro, Brian P., 59, 461B Kuang, Jennifer, 140 Leal, Paulo, 298A* Kubo, Shiori, 234C Leal, Sandra M., 256A*, 712A* Kucerova, Katerina, 135 Leatherman, J., 890B Kucerova, Lucie, 4 Leatherman, Judith, 423C, 426C Kucinski, Iwo, 307A* Le Borgne, Roland, 115, 853A Kuebler, Daniel, 537C Leclerc, Vincent, 137

SPEAKER AND AUTHOR INDEX

Lecuyer, Eric, 839B Lichinchi, Gianluigi, 834C Lécuyer, Eric, 213C Lieb, Jason D., 132 Lee, Cheng-Yu, 149*, 274A*, 432C Liestøl, Knut, 8 Lee, Chi-Hon, 535A* Li-Kroeger, David, 751A, 880A* Lee, Choong, 851B Lilly, Mary, 386B Lee, Daniel, 227B Lim, Bomyi, 91, 108, 854B Lee, Gina, 470B Lim, Su Jun, 802A Lee, Grace Y. C., 53* Lin, Haifan, 377B, 417C Lee, Hangnoh, 649A*, 863B* Lin, Li, 711C Lee, Herbert, 685A* Lin, Shuailiang, 856A, 857B Lee, Hun-Goo, 810C* Lin, Tzu-Yang, 535A Lee, Joo-Yeun, 419B* Lin, Wan-Hsuan, 825C Lee, Jung-Eun, 139* Lin, Wei-Cheng, 320B* Lee, Megan E., 650B Lin, Ya-Huei, 185B* Lee, Sangil, 548B Lin, Yanyan, 397A Lee, Tom, 201C Lin, Yong-Qi, 12 Lee, Tom Van, 231C* Ling, Jia, 105, 727A* Lee, Tzumin, 78, 858C LInk, A. James, 94 Lee, Wei-Hao, 196A Liou, Willisa, 196A Lee, Zachary, 822C Lippert, Nodia, 37 Lefrançois, Martin, 236B Lipshitz, Howard, 839B Lehmann, Kjong-Van, 509B, 697A* Lipsick, Joseph, 781A Lehmann, Michael, 569B* Little, Shawn C., 732C* Lei, Elissa P., 802A* Liu, Chung-Chih, 540C* Leiblich, Aaron, 117 Liu, Lucy, 570C* Leips, Jeff, 615C, 833B Liu, Lu-Ping, 77 Lemke, Steffen, 36, 653B, 657C* Liu, Na, 377B Lempert, Eugene, 584B Liu, Songmei, 873C Lenkeit, Christopher, 406A Liu, Xingyin, 728B* Lennox, Ashley, 240C Liu, Ze, 51 Leonard, Leah, 611B Liu, Zhonghua, 327C Leonardi, Jessica, 201C Lobell, Amanda, 673A* Leopold, Pierre, 6 Lockwood, Brent L., 321C* Lera, Matthew, 877A Lockwood, Donovan, 102 LeShay, Rebecca, 169A* Loewen, Carin A., 504C Letsou, Anthea, 228C, 246C, 563B Logan-Garbisch, Theresa, 613A Leuch, Hayley, 671B Lollar, Matthew, 599B* Leulier, François, 367A, 368B Long, Abby, 545B Leung, W., 890B Long, Anthony D., 629B Leung, Wilson, 628A, 891C Long, Manyuan, 53 Levario, Thomas J., 854B* Long, Sarah K. R., 488B Levensailor, Nancy J., 875B* Lopatto, D., 890B Levine, Mia T., 126* Lopez, Pablo, 207C Levis, Robert, 79 López Ceballos, Pablo, 208A* Levitan, Ed, 13 Loppin, Benjamin, 66 Levy, Peter, 489C Lorberbaum, David, 128 Lewellyn, Lara, 538A Lorenzo, Melissa E., 382A Lewellyn, Lindsay, 199A Losick, Vicki, 292A* Li, Airong, 473B* Lostchuck, Emily, 205A, 206B Li, Chi-Chuan, 825C Lostchuck, Emily E., 95* Li, Chong, 773B Lott, Susan E., 658A* Li, Hongjie, 439A* Lovander, Kaylee E., 18 Li, Jian-Chiuan, 825C, 826A Lovato, TyAnna L., 755B* Li, Jun, 289A Loveland, Kate L., 418A Li, Ke, 726C* Lovick, Jennifer, 483C Li, Lily, 748A Lowery, Hailey, 822C Li, Qingyun, 9, 481A Loyer, Nicolas, 115* Li, Qinqin, 119 Loza-Coll, Mariano A., 440B* Li, Shuo, 50 Lu, Bingwei, 568A Li, Tongchao, 772A Lu, Hang, 854B Li, Weizhe, 619A* Lu, Qiuheng, 186C* Li, Xiao, 839B Lu, Vivian, 462C Li, Xiao-Yong, 754A* Lücke, Thomas, 601A Li, Yeran, 789C, 796A* Ludwig, Michael, 764B Li, Yi-Chen, 196A Luecke, David, 659B* Li, Yijie, 430A* Lum, Michael J., 571A* Li, Ying, 510C Luor, David, 323B Li, Yumei, 862A Luschnig, Stefan, 85 Li, Zhihong, 570C Luscombe, Nicholas M., 107 Li, Zhuyin, 121 Lusk, Richard W., 660C*

SPEAKER AND AUTHOR INDEX

Luu, Peter, 600C* Martin, Franck, 90 Lydiard-Martin, Tara, 865A Martin, Melinda J., 18 Lye, Jessica, 257B Martín-Bermudo, María Dolores, 174C Lyman, Rachel A., 623B Martinez, Anne-Marie, 811A* Lynes, Maureen, 592A Martinez, Melody M., 755B Martinez-Agosto, Julian, 325A Martin-Peña, Alfonso, 122 Marxreiter, Stefanie M., 333C* M Marzi, Stefano, 90 Masek, Pavel, 141*, 243C, 507C, 521B, 522C Ma, Dali, 367A* Mateo, Lidia, 686B Ma, Hansong, Plenary Session II, 689B* Mateos, Julio, 60 Ma, Lijia, 34, 756C, 803B* Matis, Maja, 48 Ma, Qing, 425B*, 430A Matlock, Alex, 298A Ma, Xing, 420C* Matsuda, Muneo, 885C Mabeza, Russyan Mark, 351C Matsumoto, Kenjiroo, 230B, 232A* Macdonald, Stuart J., 54 Matsumoto, Takeo, 211A Machado, Carlos A., 661A Matsuno, Kenji, 211A, 230B, 232A, 234C, 308B Machado, Heather, 642C* Matsuoka, Shinya, 353B* MacIntyre, Ross, 842B Mattei, Vincenzo, 3 Mackay, Trudy, 519C Matthews, Beverley, 767B, 774C Mackay, Trudy F., Plenary Session II* Matthews, Kathy A., 881B Mackay, Trudy F. C., 529A, 623B Matunis, Erika, 422B, 424A, 425B, 430A MacRae, Ian J., 834C Matzat, Leah H., 802A MacWilliam, Dyan, 530B* Maung, Saw-Myat, 181A Maeda, Reo, 211A Mauntz, Ruth, 330C Maeda, Robert K., Plenary Session II, 191B Mauthner, Stephanie, 525C* Maes, Sara, 744C Mavor, Lauren, 158B Mageeney, Catherine, 378C* Maxim, Barsukov, 627C Maggert, Keith A., 65 Mayer, Fahima, 512B Mah, Kar Men, 545B Mayer, Franz, 251B Mahajan, Shivani, 771C*, 843C Mayfield, Christy, 601A Mahato, Simpla, 202A McCall, Kim, 30, 184A, 271A Maheshwari, Megha, 559A McCall, Kimberly, 187A, 395B Mai, Nakamura, 299B* McCallough, Christopher L., 719B* Maier, Zeke, 67 McCartney, Brooke M., 219C, 429C Majeski, Katharine, 403A, 411C* McClelland, Lindy, 441C* Major, James, 426C* McClure, Kimberly D., 541A* Majzoub, Karim, 90 McCluskey, Patrick, 397A Makase, Anna, 779B* McCole, Declan, 140 Makase, Anna A., 63 McCouch, Susan, 672C Makhijani, Kalpana, 138, 444C McCoy, Lenovia J., 623B Malerød, Lene, 8 McDermott, Jacqueline E., 337A Malik, Harmit, 38 McDermott, John, 364A Malik, Harmit S., 126 McDermott, Scott, 545B Malik, Jitendra, 852C McDonald, Jocelyn, 197B, 209B Malmanche, Nicolas, 562A McGlaughon, Jennifer Apger, 513C* Malmendal, Anders, 572B* McIntyre, Lauren, 509B, 697A Manak, J. Robert, 104, 545B McIntyre, Lauren M., 639C, 674B* Mancini, Greg, 561C McKay, Daniel J., 132 Mangahas, Paolo, 79 McKee, Bruce, 283A Manivannan, Sathiya, 874A McKim, Kim, 280A Manivannan, Sathiya Narayanan, 86*, 718A* McKim, Kim S., 281B Mann, Richard, 871A McLaughlin, Colleen, 491B* Mannix, Katelynn M., 170B* Mclaurin, Justin D., 116 Manno, Joseph E., 337A McLean, Peter, 390C Manquen, Jack, 464B McLinden, Kristina, 587B Mansour, Sarah, 445A McMahan, Susan, 262A Mariyappa, Daniel N., 248B* McMahon, Susan, 266B Marjoram, Paul, 511A Mcminn, Erin, 616A Markow, Therese, 654C McNeill, Elizabeth, 592A Markow, Therese A., 684C McNeill, Elizabeth M., 827B* Markow, Therese Ann, 643A McNeill, Helen, Plenary Session I*, 364A Markus, Robert, 458B McParland, Aidan L., 514A* Marmion, Robert, 722B McQuibban, Angus, Plenary Session I Marrone, April K., 605B Medvedeva, Anna, 574A Marsischky, Gerald, 857B Meehan, Tracy, 184A, 187A* Martin, Adam, 179B Megraw, Timothy, 2, 286A Martin, Adam C., 167B Mehta, Aradhana, 521B Martin, Elodie, 553A Mehta, Aradhna, 522C

SPEAKER AND AUTHOR INDEX

Mehta, Neha, 351C Montchamp-Moreau, Catherine, 665B, 777C Mehta, Nickita, 16* Montell, Denise, 160A, 198C Meier, Samuel, 646A, 729C, 788B Montooth, Kristi L., 321C, 331A, 692B Meignin, Carine, 90* Montoya, Geovanny C., 650B Melani, Mariana, 316A* Moody, Alexandra, 223A Melkani, Anju, 620B Moody, Catriona, 521B Melkani, Girish C., 550A, 620B*, 624C Mooradian, Arshag, 375C Melkov, Anna, 171C* Moore, Trish, 638B Meller, Victoria, 776B Moradian, Annie, 273C Meller, Victoria H., 814A Moran, Michael T., 561C Mellone, Barbara, 782B, 783C Moreno, Eduardo, 138 Melton, Mark A., 488B Morera, Andrés A., 573C* Melzer, Juliane, 433A Morgan, Sarah, 712A Mendes, Fabio, 688A Morimoto, Marie, 601A* Menegazzi, Brielle, 256A Morin, Gregg B., 273C Meriwether, Andrew, 712A Morozova, Tatiana V., 623B Merkle, Julie A., 391A* Morris, Quaid, 839B Merkling, Sarah, 134* Morrow, Bernice E., 306C Merle, Jacob A., 88 Morse, Alison, 697A Merriam, John R., 284B* Morse, Alison M., 509B, 639C Merriam, Jordyn Lee, 609C* Mossman, James, 695B Merritt, David, 871A Mossman, James A., 351C* Merritt, Thomas JS, 322A* Moss-Taylor, Lindsay, 499A* Metzstein, Mark M., 85 Mosure, Sarah, 414C Meyer, Wynn K., 681C* Moulton, Matthew J., 228C* Mezey, Jason, 672C Moussian, Bernard, 244A Mianecke, Maxwell, 878B Moyer, Anna, 616A Michalski, Kevin, 401B Mueller, Laurance D., 629B Michaud, S., 405C Muir, Katherine, 194B, 617B Michel, Marcus, 217A Mukherjee, Ashim, 233B Michelson, A. M., 405C Mukherjee, Avik, 285C* Miguel-Aliaga, Irene, 520A Mukherjee, Rajarshi, 559A Mihály, József, 469A Muller, Arno, 248B Milán, Marco, 70 Müller, Arno, 197B Milano, Carolyn, 396C Müller, Martin, 743B Miles, Cecelia M., 37 Murakami, Kaz, 522C Millard, S. Sean, 481A Murphey, Rod, 871A Miller, Daniel L., 621C* Murphy, Coleen, 528C Miller, Eli, 379A* Murray, Michael J., 500B Miller, Karen M. Wong, 682A* Murthy, Mala, 142, 528C Miller, Kathryn G., 375C Mutero, Annick, Plenary Session II Miller, Kylie, 344B Myung, Clara, 601A Miller, Steve W., 756C* Mills, Maya D., 88 Min, Matthew, 351C Minakhina, Svetlana, 62 N Minami, Ryunosuke, 288C Mirouse, Vincent, 295A Nagarkar Jaiswal, Sonal, 79* Mishra, Abhinava K., 233B* Nagengast, A., 890B Mishra, Rakesh, 64 Nagengast, Alexis, 844A Mishra, Rakesh K., 804C, 807C Nagengast, Alexis A., 336C Misra, Mala, 475A Naidu, Chitra, 238A* Mistry, H., 890B Najafian, Behzad, 601A Mistry, Hemlata, 888C* Najarro, Michael A., 54, 693C* Miura, Masayuki, 484A Nakagoshi, Hideki, 288C, 713B Mlodzik, Marek, 189C Nakamura, Akira, 196A Moberg, Kenneth, 5, 301A Nakazawa, Naotaka, 211A modENCODE, 649A Nambu, John, 442A, 494B, 517A Moechars, Dieder, 562A Namiki, Shigehiro, 871A Mohammad, Farhan, 883A Nandi, Nilay, 259A Mohr, Stephanie, 856A Narciso, Cody E., 275B* Mohr, Stephanie E., 855C, 857B* Naryshkina, Tatyana, 62 Moline, Christopher S., 166A Natarajan, Malini, 729C* Mollereau, Bertrand, 253A Navarro, Caryn, 192C Mollison, Lonna, 84 Nayan, Marvin, 11* Monahan, Amanda J., 427A* Nazario-Yepiz, Nestor Octavio, 643A* Mondal, Bama Charan, 446B* Neckameyer, Wendi, 476B Mondragon, Albert A., 30 Neckameyer, Wendi S., 622A* Monnier, Veronique, 553A Negre, Nicholas, 34, 756C Montague, Shelby A., 505A* Negre, Nicolas, 803B

SPEAKER AND AUTHOR INDEX

Nelson, Jonathan O., 85* Oliveira, Daniela, 91 Nemetschke, Linda, 188B* Oliver, B., 398B Neuman, Sarah, 737B* Oliver, Brian, 121, 399C, 649A, 863B Nevarez, Michael, 748A Oliver, Stacie L., 429C* Neves, Joana, 249C* Olofsson, Jessica, 48 Neville, Megan C., 508A* Olsen, Doug, 9 Newell, Nicole R., 509B* Önel, Susanne-Filiz, 193A Newell, Peter, 56, 339C Ong, Katy Lauren, 173B* Newfeld, Stuart, 492C*, 866B Onorati, Maria Cristina, 818B Ng, Chun, 17 Orenic, Teresa V., 719B Ng, Chun Leung, 428B* Orgogozo, Virginie, 684C, 870C* Ng, Spencer, 844A Orng, Souvinh, 512B Nguyen, Aiden, 555C* Orr-Weaver, Terry, 27, 394A, 821B Nguyen, Brittney, 453C Orr-Weaver, Terry L., 1, 823A Nguyen, John, 555C Orsi, Guillermo, 66 Ni, Jian-Quan, 77 Osiecki, David M., 392B* Ni, Xiaochun, 69 Ostapenko, Alexander, 34 Nie, Jing, 202A* Ostapenko, Sasha, 803B Nie, Qian, 293B* O'Sullivan, Niamh, 590B Niepielko, Matthew G., 239B* Otazo, Maria, 459C Nieto, Andres, 622A Ott, Stanislav, 572B Nikitina, Ekatherina, 574A* Ou, Qiuxiang, 347B*, 349A Nilson, Laura, 172A, 705C Ovcharenko, I., 405C Nina, Kutuzova, 627C Overheul, Gijs, 134 Nishimura, Takashi, 360C Owusu-Ansah, Edward, 69 Nitabach, Michael, 145, 534C Oyallon, Justine, 470B* Nizet, Victor, 140 Ozdowski, Emily F., 576C* Njuguna, Maureen, 891C Noblett, Christian, 759C Nocka, Arsida, 172A* Nodal, Dalea, 220A* P Nojima, Tetsuya, 508A Nordman, Jared T., 823A* Pachter, Lior, 835A Norvell, Amanda, 848B*, 849C Page, Jennifer L., Plenary Session II Noselli, Stephane, 40* Page-McCaw, Andrea, 203B, 222C Nowak, Scott, 403A, 411C Pai, Li-Mei, 196A, 320B, 393C* Nukina, Nobuyuki, 559A Pak, Gloria, 341B Nuzhdin, Sergey, 509B, 674B, 697A, 770B Palagani, Preethi V., 61 Nuzhdin, Sergey V., 511A, 639C, 680B, 879C Palandri, Amandine, 553A Nyberg, Kevin G., 661A* Palanker Musselman, Laura, 67* Nystul, Todd, 154 Pal-Bhadra, Manika, 269B, 790A Paliouras, Miltiadis, 577A* Paliwal, Nidhi, 578B* O Palladino, Jason T., 782B* Pallavi, S. K., 97 Palmiter, Richard, 570C Oakes, Patrick W., 199A Palter, Karen, 555C O'Brien, Katherine, 58, 642C Paluch, Jeremy, 502A O'Connell, Michael D., 720C* Panchal, Trupti, 412A O'Connor, Michael, 499A Pannikar, Chitra, 819C O’Connor, Michael, 444C Parham, David, 601A O'Connor-Giles, Kate M., 75* Parida, Mrutyunjaya, 545B Ocorr, Karen, 551B* Parikh, Kosha, 323B Odell, Nadia, 215B Parillaud, Vincent, 470B Odenwald, Ward F., 757A Park, Sangbin, 68, 120* Odom, Kelly, 256A Parkash, Ravi, 678C, 690C, 700A, 701B, 702C O'Donnell, Janis, 496A, 557B, 599B, 616A Parker, Ashley, 602B O'Donnell, Janis M., 456C Parker, Ashley L., 340A*, 348C, 350B Odumosu, Morolake, 575B* Parker, Darren, 508A O'Farrell, Patrick, 689B, 799A Parker, David, 128 O'Farrell, Patrick H., Plenary Session II* Parkhurst, Susan, 178A Offerdahl, Katelyn, 243C Parks, Annette L., 881B* Ogereau, David, 665B, 777C Parks, Cory, 822C O'Grady, Patrick, 683B Paroush, Ze'ev, 736A Ohsawa, Shizue, 294C, 308B Parrish, Jay, 11 Okamoto, Naoki, 360C* Parsons, Travis, 229A O'Kane, Cahir, 590B Parsons, Trish, 882C Okumura, Misako, 484A* Partridge, Linda, 359B, 564C Okumura, Takashi, 355A Patel, Parthiv H., 546C Okuwa, Sumie, 481A Patel, Seema, 229A*

SPEAKER AND AUTHOR INDEX

Pathak, Rashmi U., 804C Pope, Nicole, 722B* Patrnogic, Jelena, 137* Port, Fillip, 858C* Pavlou, H., 398B Posakony, James W., 740B, 756C Payre, François, 244A Post, Stephanie, 361A* Payre, Francois, 772A Pradhan, Tirthadipa, 221B* Pearcy, Rachel, 579C* Prasad, Mohit, 198C Pearman, Krista, 500B Pratap Singh, Narendra, 807C Pearson, Antony, 847A Pray, Victoria A., 623B* Pearson, John, 416B Prazak, Lisa, 100, 752B Peel, Emily, 616A Pribadi, Amy, 580A*, 591C Pek, Jun Wei, 841A* Primus, Shekerah, 400A* Peláez, Nicolás, 111 Prince, Elodie, 191B* Pélissier-Monier, Anne, 244A Prokhor, Proshakov, 627C Peñaloza, Fernando, 654C Pronikov, Vladimir, 574A Perdigoto, Carolina N., 435C Pronovost, Stephen M., 168C Pereira, Emiliana, 250A Prud'homme, Benjamin, 777C Pereira, Paulo S., 250A Przybyla, Fletcher, 227B Pereira, Telmo, 312C Przytycka, T., 398B Perera, Sumeth, 117 Przytycka, Teresa, 863B Perez, Tristan, 142 Ptashkin, Ryan, 803B Pérez-Moreno, Juan José, 174C* Puli, Oorvashi Roy, 561C Perez Perri, Joel, 316A Puli, Oorvashi Roy G., 713B* Perkins, Lizabeth, 855C Pushpavalli, Sncvl, 269B Perlaza, Karina, 584B Pyfrom, Sarah C., 382A Perlman, David, 91 Pykalainen, Anette, 176B* Pero, Mariah, 884B Peronnet, Frédérique, 806B Perrimon, Norbert, 69, 245B, 766A, 827B, 834C, 855C, 856A, 857B Q Peters, Michelle, 500B Peters, Nathaniel C., 195C* Qi, Yanyan, 439A Petersen, Andrew, 560B Qi, Yun, 125* Peterson, Jeanne, 395B Qian, Yue, 17* Petraki, Sophia, 444C Qiao, Nan, 480C Petrov, Dmitri, 58, 642C, 669C Qiu, Bitao, 828C Petrova, Boryana, 394A* Quan, Allison, 683B* Pfeiler, Edward, 643A Quenerch'du, Emilie, 831C* Pfleger, Cathie, 181A Quijano, Janine, 492C Phadnis, Nitin, 38* Quintana, Albert, 570C Pham, Christine K., 531C* Quiquand, Manon, 480C* Pham, Linh, 591C Phan, Trung, 380B* Phelps, Brian, 347B Philippi, Nicole, 359B R Phillips, Mark A., 629B Pick, Leslie, 666C Pickering, Robert, 383B Raabe, Isabel, 217A Piddini, Eugenia, 307A, 445A, 447C Raabe, Thomas, 433A Pile, Lori, 787A Rabe, Amanda, 465C Piloto, Sarah, 552C* Rabouille, Catherine, 51 Pindyurin, Alexey, 823A Rachfalski, Caroline, 602B Pineton de Chambrun, Guillaume, 140 Raffa, Grazia Daniela, 3 Pires, Elisabete, 15 Raftery, Laurel, 224B, 229A Pirrotta, Vincenzo, 810C Rahman, Mokhlasur, 498C* Pischedda, Alison, 675C*, 676A, 679A Rambukwella, Mishan D., 462C Plaza, Serge, 244A, 772A* Ramirez, AnnJosette, 340A, 348C, 350B, 602B*, 608B Plessis, Anne, 216C Ramírez-Loustalot-Laclette, Mariana, 643A Pletcher, Scott, 74, 139 Ramirez-San Juan, Guillermina R., 199A Pletcher, Scott D., 318C, 341B, 344B, 358A Ramniwas, Seema, 690C* Pohida, Thomas, 535A Ramos, Andrea, 128 Poirier, Enzo, 445A Ramos, Andrea Isabel, 738C* Pokrywka, Nancy J., 175A* Ramos, Raul, 620B Polak, Grzegorz, 354C* Ramroop, Johnny, 459C Polesello, Cédric, 244A Ramsey, Katrina, 366C Polevoy, Gordon, 180C Rana, Tariq M., 834C Polihronakis Richmond, Maxi, 643A, 684C Rand, David, 335B, 351C Politi, Kristin, 223A Rand, David M., 332B, 695B* Ponce, Jessica, 610A* Randolph, Haley E., 650B* Pool, John, 636C, 641B, 667A Randolph, Kristen, 848B Poon, Peter, 509B, 697A Randsholt, Neel B., 806B

SPEAKER AND AUTHOR INDEX

Ranga, Poonam, 702C* Roesler, Mona, 514A Ranz, José, 703A Rogers, Kealie, 545B Rao, Prashanth, 711C* Rogers, Rebekah L., 632B* Rath, Uttama, 258C Rollins, Janet, 387C Rathke, Christina, 735C Rollmann, Stephanie M., 527B Ratliff, Eric, 330C, 624C* Romani, Patrizia, 345C Ray, Anandasankar, 530B, 531C Romanov, Denis A., 645C Ray, Arjun, 506B* Romberger, Catherine, 581B* Rebay, Ilaria, 111 Romero, Nuria, 316A Rebeiz, Mark, 106* Ron, David, 15 Reddy, Curran, 523A Ronsseray, Stephane, 89 Redhai, Siamak, 117* Ronzhina, Natalia L., 63 Ree, Brandy, 569B Rose, Michael R., 629B Reed, L., 890B Rosenberg, Todd, 238A Reed, Laura, 594C, 609C, 611B, 638B Rosenfeld, Robyn, Plenary Session I Reed, Laura K., 596B, 668B Rosenheck, Sarah M., 337A Reeves, Gregory, 704B Rosenwasser, Claire, 238A Reeves, Gregory T., 43, 720C Rosin, Leah, 783C* Reeves, Nick L., 891C* Ross, Jermaine, 757A* Reeves, NL, 890B Rossier, Mikaël, Plenary Session II Regruto, Lindsay, 381C Rota, Christopher, 262A* Reich, John, 386B Röthlisberger, Michael, 6 Reichhart, Jean-Marc, 137 Roy, Sougata, 93*, 711C, 717C, 873C* Reid, Benjamin, 867C Roychoudhury, Kaushik, 375C Reijmers, Leon, 144 Roy Chowdhury, Debabani, 832A* Reim, Ingolf, 22 Ruan, Kai, 773B* Reinitz, John, 764B Rubaharan, Myurajan, 471C, 472A Reiss, Kristina M., 166A Rubin, Gerald, 145, 507C, 534C Reist, Noreen E., 504C* Rubin, Gerald M., 505A Reiter, Larry, 599B Rubin, Gerry, 506B Reiter, Lawrence, 338B Rubin, Lee, 592A Reiter, Lawrence T., 598A, 603C* Rubinstein, C. Dustin, 75 Reitz, Allen, 102 Rudd, Kirstin, 857B Relvas, João B., 250A Rudnicki, Olivia, 30 Ren, Xingjie, 77 Rudolf, Katrin, 45* Ren, Yixin, 50 Rui, Yanning, 593B Renkawitz-Pohl, Renate, 735C Rummings, Wayne, 265A* Restifo, Linda L., 872B Rus, Florintina, 326B Reubens, Michael, 265A Rushlow, Christine, 108 Reubens, Michael C., 264C* Russell, Astrid, 891C Reyes, Alexis A., 493A* Russell, Steven, 508A, 863B Reynolds, Lauren, 521B Russo, Susan, 767B, 774C Reynolds, Lauren A., 73* Russomanno, Alessio, 323B Rhiner, Christa, 138 Rust, Marco, 193A Ribeiro, Valérie, 806B Ryan, Kathryn M., 758B* Rice, Clinton, 706A, 741C Ryan, Sarah, 324C Rice, Gavin R., 662B* Ryoo, Hyung Don, 15 Richards, Christopher D., 257B* Ryu, Taehyun, 797B* Richards, Stephen, 35, 648C, 650B Ryu, Taeyun, 61 Ricketti, Daniel, 323B* Riddiford, Lynn, 343A Riddle, Nicole, 780C* Rieder, Leila E., 815B* S Riesgo-Escovar, Juan, 836B Riesgo-Escovar, Juan R., 643A Saadin, Afsoon, 242B* Riggs, Blake, 116, 177C, 278B, 542B Saalfeld, Stephan, 483C Rincon-Limas, Diego, 122, 582C Sachan, Nalani, 233B Rios, Marlyn, 227B Sadaf, Sufia, 524B* Ríos-Barrera, Luis Daniel, 836B* Saelao, Perot, 647B Ritchie, Michael, 508A Sahani, Sadhna, 883A Ro, Jennifer, 341B* Sakr, Samy, 811A Ro, Jenny, 344B Sakuma, Chisako, 484A Robbins, Renee M., 404B* Salazar, Raul, 651C Roberts, David, 219C, 223A Saleque, Shireen, 459C Robinson, Douglas, 50 Salomon, Matthew, 462C, 509B, 697A Rockel, Claudia, 730A* Salomon, Matt P., 640A Rodan, Aylin, 501C Salz, Julia B., 511A Rodriguez, Janel, 812B* Samakovlis, Christos, 241A Roebke, Austin, 309C, 544A* Samee, Md A. Hassan, 865A* Roesel, Charles, 855C, 856A, 857B Samper, Núria, 736A

SPEAKER AND AUTHOR INDEX

Sampson, Leesa, 156, 353B Sechi, Stefano, 3 Sanchez, Alejandro, 654C Secombe, Julie, 728B Sanchez, Gabriel A., 891C Seeds, Andrew, 871A Sanchez-Garcia, Jonantan, 122 Segal, Dagan, 214A* Sanchez-Garcia, Jonatan, 582C* Sehgal, Amita, 431B Sandall, Sharsti S., 440B Sekelsky, Jeff, 262A, 266B Sanderford, Maxwell, 869B Selfon, Rachel, 756C Sandmann, Thomas, 36 Selvaraj, Bhavani, 874A Sandoval, Hector, 12*, 570C, 588C, 862A Sem Wegner, Catherine, 8 Sane, Sanjay, 524B Sen, Anindua, 592A Sanford, J., 890B Senaratne, Tharanga Niroshini, 816C* Sanghavi, Paulomi B., 192C* Sengupta, Saheli, 258C* Sanial, Matthieu, 216C Sennett, Kristyn, 538A Saniya, Deshmukh, 819C Sensibaugh, Cheryl A., 755B Sannino, David, 56 Sentmanat, Monica, 793A Sansone, Christine L., 133* Senturk, Mumine, 585C* Santana, Juan, 545B* Serbus, Laura R., 465C*, 466A Sanyal, Subhabrata, 324C Serizier, Sandy, 184A Sapey-Triomphe, Laure, 66 Serpe, Mihaela, 14, 478A Sariaydin, Nuray, 323B Sester, David, 277A Sarkar, Ankita, 583A* Shaffer, C., 890B Sarkar, Arpita, 269B* Shaffer, Christopher, 628A Sasamura, Takeshi, 230B, 232A Shaffer, Christopher D., 891C Saucier, Joseph, 712A Shahandeh, Michael, 675C, 676A* Saul, Joshua, 363C Shain, Daniel, 323B Savall, Joan, 864C* Shanbhag, Riya, Plenary Session I Savvateeva-Popova, Elena, 574A Shanku, Alexander G., 691A* Sawant, Ketki, 209B* Shannon, Erica, 203B* Sawyer, Eric M., 381C* Shao, Ling, 632B Sawyer, Jessica, 198C Sharma, Ankit, 559A Schaeffer, Stephen, 35, 648C Sharp, Katherine, 48* Schaeffer, Stephen W., 650B Sharrow, Mary, 16 Schafer, Dorothy, 186C Shaw, Jillian L., 586A* Schaub, Christoph, 22 Shaw, Matthew, 868A Schauder, Curtis, 62 Shcherbata, Halyna, 352A Schedl, Paul, 743B Shcherbata, Halyna R., 605B Schejter, Eyal, 214A, 707B Shen, Min, 121 Schellinger, Jeffrey, 501C Shen, Yang, 828C* Schenck, Annette, 134 Shendure, Jay, 38 Schenkel, Claire E., 30 Shepherd, David, 871A Schiabor, Kelly M., 696C* Shermoen, Tony, 799A Schleede, Justin, 225C Sherwood, Nina T., 576C Schlenke, Todd, 698B Shiao, Shin-Hong, 733A* Schlessinger, Saundra, 366C Shilo, Benny, 214A, 707B Schmidt, Paul, 58, 452B, 642C Shipman, Anna, 291C Schmidt-Glenewinkel, Thomas, 584B* Shirangi, Troy, 871A Schmidt-Ott, Urs, 36, 709A Shizue, Ohsawa, 299B Schnall-Levin, Michael, 827B Shloma, Victor, 823A Schneemann, Anette, 834C Shokri, Leila, 105 Schneider, David, 135 Shrestha, Bhupal G., 546C* Schneider, David S., 103, 453C Shridhar, S., 859A Schnitzer, Mark, 864C Shubeita, George T., 81 Schrider, Daniel R., 644B*, 688A Shum, Axel, 646A Schroeder, Andrew, 767B, 774C Shvartsman, Stanislav, 108 Schulman, Victoria K., 21* Shvartsman, Stanislav Y., 94, 854B Schulz, Cordula, 17, 428B Sidorov, Roman, 4 Schulz, Katharine N., 132* Sieber, Matt, 19* Schulze, Karen, 79 Siefert, Matthew, 487A* Schupbach, Trudi, 91 Siems, Lauren S., 817A* Schüpbach, Trudi, 254B, 391A, 409A Siezen, Roland, 368B Schuster, Catherine, 90 Signor, Sarah A., 677B* Schuttengruber, Bernd, 811A Silva, Diane, 406A Schütz, Lucas, 657C Silverman, Neal, 326B Schwartz, Yuri, 810C Simchoni, Yasmin, 171C Schweisguth, François, 435C Simcox, Amanda, 86, 718A, 810C, 874A* Scroggs, Reese, 603C Simon, Claudio, 274A Searles, Lillie L., 84* Simon, Felix, 470B Sears, James, 474C* Simone, Angila, 846C Sebo, Zach, 357C Simonoski, Ursula, 891C Sebo, Zachary, 362B* Simons, Benjamin, 445A

SPEAKER AND AUTHOR INDEX

Simpson, Julie H., 80, 146 Stofanko, Martin, 590B Sims, Amanda M., 177C* Stoffregen, Eric P., 266B* Sing, Anson, Plenary Session I Stone, Lauren, 876C Singh, Amit, 276C, 309C, 561C, 567C, 583A, 713B, 714C Storelli, Gilles, 368B* Singh, Divya, 678C* St. Pierre, Susan E., 767B, 774C* Singh, Nadia, 698B Stralis-Pavese, N., 859A* Singh, Shama, 694A* Stroebele, Elizabeth, 42, 652A, 759C* Singh, Shweta, 494B* Stroh, Colette, 604A Sinha, Saurabh, 663C*, 865A Stronach, Beth, 240C*, 882C* Sinha, Sucheta, 385A Stumph, William, 731B Sitaraman, Divya, 145*, 534C Sturgill, D., 398B Siudeja, Katarzyna, 152* Su, Ashley, 227B Skeath, James, 888C Su, TinTin, 28* Skelly, Kathleen-Rose, 68 Suggs, Jennifer A., 620B, 624C Skolfield, Shelly, 698B Sugita, Shukei, 211A Skopek, Joseph, 541A Suh, Yoon Seok, 829A* Skorski, Patricia, 152 Suijkerbuijk, Saskia, 445A Slattery, Matthew, 34, 480C, 756C, 803B Suijkerbuijk, Saskia JE, 447C* Slone, Jesse, 533B SUlkowski, Mikolaj J., 14* Small, C., 890B Sullivan, Luis, 143 Small, Chiyedza, 459C* Sullivan, William, 465C, 466A Small, Stephen, 727A Sultan, Abdel-Rahman, 369C Small, Steve, 105 Sumabat, Taryn, 118 Smith, Chris, 634A Sun, Dan, 25* Smith, Curtis C., 891C Sun, Jianjun, 414C* Smith, H., 398B Sun, Qian, 866B*, 869B Smith, Robert, 256A Sun, Y. Henry, 261C, 485B Smith, S., 890B Sun, Yujia, 108 Smith, Sheryl T., 340A, 348C, 350B, 602B, 608B Suo, Shengbao, 480C Smith-Bolton, Rachel, 310A, 813C Svetec, Nicolas, 647B* Smith-Bolton, Rachel K., 314B, 715A Svetlana, Sorokina, 627C Smykal, Vlastimil, 346A Swamy, Harsha, 476B Snee, Mark, 888C Swan, Andrew, 260B Sobala, Lukasz F., 413B* Swanson, Christina, 128 Sokac, Anna, 110 Swavey, Shawn, 604A Soll, David, 706A Swenson, Joel, 792C, 798C* Somer, Rebecca A., 334A* Swezey, Elizabeth R., 495C* Song, Wei, 69* Swingle, Kirstie L., 755B Song, Xiangyu, 533B Song, Xiaoqing, 420C Sopko, Richelle, 855C Sorianello, Eleonora, 316A T Sorokina, Svetlana Y., 645C* Sotelo-Troha, Katia, 463A* Taborda, Joanna, 442A* Sotillos, Sol, 182B Tabtiang, Anisa, 622A Souders, Christopher L., 509B Takaesu, Norma, 492C Southall, Tony, 440B, 508A Takano, Toshiyuki, 885C Spana, Eric P., 889A* Takano-Shimizu, Toshiyuki, 664A* Spencer, Susan, 293B Takeda, Koji, 355A* Spirov, Alexander V., 44*, 763A Takino, Kyoko, 294C* Spokony, Rebecca, 34, 244A, 803B Tamada, Masako, 47* Spracklen, Andrew, 52* Tan, Kai Li, 862A Spracklen, Cassandra, 52 Tanaka, Tsubasa, 196A Spradling, Allan, 19, 79, 292A, 414C Tanda, Soichi, 739A Spurrier, Joshua, 587B* Tanentzapf, Guy, 95, 199A, 205A, 206B, 207C, 208A, 373A Srinivasan, Shruthi, 212B Tang, Sherry, 860B Staber, Cynthia, 646A* Taniguchi, Kiichiro, 288C*, 355A Stacey, Katryn, 277A Tanner, Elizabeth, 395B Staller, Max V., 734B Tanzi, Rudolph, 473B Starz-Gaiano, Michelle, 242B, 427A Tao, Rong, 856A Stathopoulos, Angelike M., 24* Tare, Meghana, 561C Stein, Dave, 82* Tatar, Marc, 326B, 361A Steinhauer, Josefa, 379A Tate, Rebecca, 473B Stenesen, Drew, 501C* Tatsushi, Igaki, 299B Stenmark, Harald, 8 Tavare, Simon, 697A Stern, David, 746B Tavaré, Simon, 509B Stern, David L., Plenary Session I*, 142 Tavares, Ligia, 250A* Stevens, Traci L., 166A Taylor, Jeffrey, 30, 184A, 187A Steward, Ruth, 62 Taylor, J. Paul, 102 St. Martin, Genevieve, 867C Teixeira, Lisa, 651C

SPEAKER AND AUTHOR INDEX

Tello, Judith, 872B Tully, Tim, 868A Tenenbaum, Conrad M., 475A* Tunckanat, A. Cigdem, 611B* Teng, Xiuyin, 119 Tung, Shu-Yun, 421A Terwilliger, Nathanael R., 875B Turkson, Susie A., 53 Texada, Michael, 343A Turner, Heather, 143 Teysset, Laure, 89 Turner, Thomas, 675C, 676A Thackeray, Justin, 238A Turner, Thomas L., 55, 679A*, 693C Theofel, Ina, 735C* Turner, Tiffany, 867C Theopold, Ulrich, 458B Turvy, Mary, 317B Therrien, Marc, 124, 236B Tuthill, John, 871A Thiemann, Dylan, 610A Tworoger, Michael, 167B Thomas, Alexander, 704B Tyra, Lauren K., 259A* Thomas, Aubin, 60, 811A Tzer-Min, Kuo, 607A Thomas, Caroline, 472A Thomas, Jeffrey H., 161B Thomas, Sean, 237C Thomas, Sharon, 283A U Thompson, James, 449B Thompson, Letitia, 848B, 849C* Ueda, Hitoshi, 369C* Thornton, Kevin, 632B Ueda, Ryu, 76, 885C Threadgill, David, 519C Ugur, Berrak, 862A Thum, Andreas, 148 Ugur, Berrak A., 588C* Thummel, Carl S., 333C, 334A, 612C Uhlirova, Mirka, 345C, 346A Tian, Yuan, 314B, 813C* Ukken, Fiona P., 75 Tiemeyer, Katherine, 16 Ullastres, Anna, 686B Tiemeyer, Michael, 16 Ulmschneider, Kiri, 793A Tikhonov, Mikhail, 732C Umeh, Maxine, 840C Timmons, Allison, 187A Unckless, Robert L., 59* Timmons, Allison K., 30* Urbach, Rolf, 433A Ting, Chau-Ti, 665B* Urban, Joachim, 838A Tito, Antonio, 593B Urbansky, Silvia, 657C Tobler, Ray, 58 Uyetake, Lyle, 28 Togane, Yu, 268A Toggweiler, Janine, 547A* Tomancak, Pavel, 483C Tomaru, Masatoshi, 664A V Tootle, Tina, 52 Topper, Sydni M., 120 Toranzo, Randy, 712A Vaadia, Rebecca, 515B* Torres, Roberto, 886A Vaders, Rebecca A., 336C* Tower, John, 697A Valdes, Frank, 872B Tracey, W. D., 147* Valdez, Colleen, 603C Tracey, W. Daniel, 525C, 860B Valenti, Philippe, 244A Tran, Nancy, 492C Valice, Emily, 660C Tran, Susan, 455B Valko, Ayelen, 316A Tran, Thanhlong G., 833B* Van, M. Jennifer, 471C Tran, Thu, 302B van Aalten, Daan, 248B Trapp, Andra, 878B Vander Wende, Helen M., 126 Traquete, Rui, 250A Van Doren, M., 398B Treisman, Jessica, 467B, 470B Van Doren, Mark, 400A Tricoire, Herve, 553A* Van Hijum, Sacha, 368B Trifiro, Mark, 577A VanKuren, Nicholas, 53, 633C Trotto, Gina, 541A van Rij, Ronald, 134 Trujillo, Adriana, 550A van Sorge, Nina, 140 Trujillo, Gloriana, 220A Van Vactor, David, 592A, 827B Truman, James, 343A, 871A Varada, Abhyankar, 819C Trunnell, De'Anna, 557B Varija Raghu, Shamprasad, 883A* Truong, Lina, 224B Vasavan, Biju, 260B* Tsai, Kun-Nan, 825C, 826A Vaughn, Jack, 769A, 846C Tsai, Yi-Cheng, 196A* Vaughn, Jack C., 845B* Tsai, Yu-Chen, 261C* Vedenko, Anastasia, 105 Tsarouhas, Vasilios, 241A* Venczel, Kevin, 317B Tsatskis, Yonit, Plenary Session I Venken, Koen, 79 Tschapalda, Kirsten, 121 Venken, Koen J. T., 862A Tseng, Chen-Yuan, 421A* Venugopal, Parvathy, 295A* Tsuboi, Alice, 308B* Veraksa, Alexey, 5, 94 Tsujimura, Hidenobu, 268A* Verboon, Jeffrey M., 178A* Tsung, Karen, 254B Verghese, Shilpi, 276C*, 304A, 309C Tsutsumi, Ayaka, 268A Verheyen, Esther, 221B Tulina, Natalia M., 431B* Verma, Neha, 731B*

100

SPEAKER AND AUTHOR INDEX

Verma, Shreekant, 804C* Warr, Coral G., 39, 708C Verrijzer, Peter, 823A Warrick, John, 538A, 579C, 581B Vesala, Laura, 448A* Watada, Masayoshi, 885C* Vesenka, Gwendolyn Davis, 516C* Watanabe, Louis, 780C Vibranovski, Maria, 633C* Watanabe, Masahide, 664A Vicoso, Beatriz, 32* Watnick, Paula, 140 Villa-Cuesta, Eugenia, 335B*, 342C*, 614B Watnick, Terry, 619A Villa Cuesta, Eugenia, 351C Watson, Alicia R., 875B Vincent, Alain, 22* Wawersik, Matthew, 425B Vincent, Ben, 734B Wayne, Marta L., 639C Vincent, Jean-Paul, 96 Weasner, Bonnie, 760A* Vincent, Stephane, 253A* Weeks, Daniel, 706A Vishal, Kumar, 317B* Wei, Ho-Chun, 180C Vitak, Nazarii, 277A* Wei, Kevin H.-C., 57* Vladimir, Mitrofanov, 627C Wei, Youheng, 386B Vlaho, Srna, 770B Weinberg, Seth, 882C Volk, Talila, 49 Weiner, Amber, 602B Volkan, Pelin C., 9*, 481A* Weiner, Amber K., 340A, 348C*, 350B, 608B Volkenhoff, Anne, 458B Weinrich, Jarret, 523A von Grotthuss, Marcin, 703A Weissman, Jonathan S., 87 von Kalm, Laurence, 876C, 884B Weiszmann, Richard, 109 Vrailas-Mortimer, Alysia D., 324C* Welch, Lonnie, 739A Vyas, Aditi, 739A* Wells, Michael B., 356B* Weng, Mo, 46* Wharton, Kristi, 13 Whisstock, James C., 39, 708C W White, Benjamin, 535A White, Benjamin H., Plenary Session I*, 515B Wachner, Stephanie, 444C White, Joseph, 164B, 212B Wade, William D., 460A* White, Kevin, 34, 244A, 480C, 803B Waghmare, Indrayani, 304A, 309C*, 544A White, Kevin P., 37, 756C Wagner, Bethany L., 382A* White, Kristin, 267C Wainwright, Mark, 117 White, Pamela, 465C Wakimoto, Barbara, 380B, 824B White, Pamela M., 466A* Walker, David, 98 White, P. Signe, 692B Wall, Dennis, 827B White-Cooper, Helen, 383B*, 850A* Wallrath, Lori, 610A Whiteman, Noah, 631A, 687C Walls, Stanley M., 554B* Whitfield, Zachary, 394A Wamsley, Brie, 470B Whitworth, C., 398B Wan, Chih-Ling, 421A Whitworth, Cale, 399C Wang, Chao, 789C* Widmann, Annekathrin, 148* Wang, Cheng, 518B Wieczorek, Michal, 213C Wang, Fei, 62* Wieschaus, Eric, 46 Wang, Huashan, 434B Wieschaus, Eric F., 26, 732C Wang, Lan-Hsin, 272B* Willecke, Maria, 547A Wang, Minpei, 884B* Williams, Byron, 706A Wang, Peggy, 130 Williams, Darren, 871A Wang, Pei-Yu, 196A, 393C Williams, Jessica, 837C Wang, Peng, 796A Wilson, Carrie B., 84 Wang, Qi, 478A* Wilson, Chris, 13 Wang, Qian, 481A Wilson, Clive, 117 Wang, Qiming, 206B Winkle, James J., 382A Wang, Shuoshuo, 49* Winkler, Lauren, 748A Wang, Su, 155* Wint, Jinelle, 742A Wang, Wei, 327C, 761B Wisidagama, Dona Roonalika, 612C* Wang, Xiaobo, 198C Wittkopp, Patricia, 660C Wang, Xiaoxi, 222C* Wittkorn, Erika L., 714C* Wang, Xing, 300C Wojtowicz, Inga, 721A Wang, Xingjun, 589A Wolff, Edward, 602B Wang, Yaqi, 769A, 846C* Wolfner, Mariana, 396C Wang, Yiping, 481A Wolfner, Mariana F., 401B, 513C Wang, Zhipeng, 140 Wolpe, Jacob, 297C Wang, Zhiqiang, 589A Wong, Chun-nin, 56 Wang, Zongheng, 51* Wong, Daniel, 325A* Wan-Hsuan, Lin, 607A Wong, Raymond, 180C Wappner, Pablo, 316A Wons, Kevin, 723C Ward, Robert, 255C, 298A Woods, Daniel, 685A Ware, Vassie, 378C Worden, Kurtresha, 507C* Ware, Vassie C., 768C Worley, Melanie I., 315C* Warner, Raechel, 343A Wu, Chao-ting, 816C

101

SPEAKER AND AUTHOR INDEX

Wu, Chun-Fang, 104 Yates Jr. III, John R., 449B Wu, Chung-I, 828C Yavuz, Ahmet E., 533B* Wu, C.-ting (Ting), 282C Ye, Jieping, 866B, 869B Wu, Jianni, 9 Yee, Stephanie, 213C, 577A, 839B* Wu, Jodie, 613A Yeh, Chun-Hung, 584B Wu, Jun, 189C* Yeh, Shu-Dan, 703A* Wu, June-Tai, 540C Yelick, Julia, 827B Wu, Lani, 10 Y. Henry, Sun, 486C Wu, Siqi, 109 Yi-Chun, Chen, 607A Wu, Zhihao, 568A Yildirim, Sukriye, 180C* Wunderlich, Zeba B., 734B Yilmazel, Bahar, 857B Wu-Woods, Jessica, 685A Yoder, John, 761B Wyskiel, Emily R., 719B Yoho, Joshua, 604A* Yokokura, Takakazu, 592A* Yonashiro, Ryo, 568A Yoo, Sa Kan, 7* X Yorimitsu, Takeshi, 713B Yoshikawa, Seiko, 592A Xiang, Jie, 666C* Young, Grant, 610A Xiang, Jinyi, 443B* Yu, Bin, 109 Xiao, Hui, 449B* Yu, Hung-Hsiang, 826A Xiao, Qi, 432C, 525C Yu, Jenn-Yah, 415A Xie, Shicong, 179B* Yu, Kweon, 829A Xie, Ting, 420C Yu, Wei-Chung, 665B XIe, Ting, 155 Yu, Yachuan, 850A Xiong, Bo, 862A Yu, Zhongxin, 601A Xiong, Xiao-Peng, 834C Yuan, Bingbing, 27 Xu, Chenling, 634A* Yuan, Kai, 799A* Xu, Heng, 110* Yuan, Xin, 759C Xu, Hong, Plenary Session II, 125, 689B Yunes, Sarah, 187A Xu, Jiang, 77* Yurgel, Maria E., 522C* Xu, Jie, 133 Xu, Tian, 548B* Xu, Wenjian, 5 Z Xu, Xiang-Ru, 716B Xu, Zhen, 593B Xue, Lei, 245B, 589A* Zachary, Eli D., 539B Zale, Connor, 237C Zallen, Jennifer, 47 Zambon, Alexander, 549C Y Zanet, Jennifer, 772A Zang, Shaoyun, 773B Yadav, Suman, 625A* Zaragoza, George, 651C Yagi, Ryohei, 251B* Zarnescu, Daniela, 102, 573C, 580A Yakoby, Nir, 239B, 323B, 722B Zarnescu, Daniela C., 591C, 847A Yalcin, Belgin, 590B* Zartman, Jeremiah, 275B, 289A Yalonetskaya, Alla, 395B* Zeidler, Martin P., 99* Yamada, Hirotsugu, 283A Zeidman, Anna, 815B Yamada, Ryuichi, 136* Zeitlinger, Julia, 108, 129*, 646A, 729C, 788B Yamada, Shizuka, 102, 580A Zelhof, Andrew, 202A Yamada, Shizuka B., 591C* Zeng, Jie, 349A* Yamakawa, Tomoko, 230B, 232A, 234C* Zeng, Xiankun, 436A Yamaki, Takuo, 824B* Zeng, Xiaomei, 15 Yamamoto, Shinya, 12, 570C, 585C, 588C, 862A Zhai, R.Grace, 773B Yamulla, Robert, 223A* Zhai, R. Grace, 159C, 454A Yan, Rihui, 283A Zhang, Can, 5* Yan, Shun, 761B* Zhang, Dachuan, 480C Yang, Hairu, 450C* Zhang, Fan, 434B* Yang, Liu, 94* Zhang, Fujian, 194B, 617B Yang, Qian, 53 Zhang, Haiyue, 752B Yang, Xiaohang, 434B Zhang, Ke, 570C, 862A Yannink, Jean-Luc, 672C Zhang, Sheng, 593B* Yao, Changfu, 258C, 279C, 796A Zhang, Yifei, 300C* Yao, Chi-Kuang, 12 Zhang, Zijing, 396C* Yao, Liqun, 241A Zhao, Li, 33* Yassin, Amir, 636C, 667A* Zhao, Ying, 194B, 617B Yasuda, Glenn, 824B Zhao, Yong, 827B Yasunaga, Ari, 133 Zheng, Kan Hong, 164B, 212B Yates, Erika, 338B Zheng, Wenjing, 326B* Zheng, Xiaowei, 248B

102

SPEAKER AND AUTHOR INDEX

Zhimulev, Igor, 823A Zhou, Fanli, 518B Zhou, Jun, 218B Zhou, L., 890B Zhou, Pinglei, 767B, 774C Zhou, Qi, 127*, 843C Zhou, Rui, 834C* Zhou, Shanshan, 529A Zhu, Cheng, 527B Zhu, Dianhuiz, 35, 650B Zhu, X., 405C Zhu, Yongqing, 119 Zhuang, Shufei, 215B Zhuang, Xiaoxi, 53 Zhulin, Igor, 283A Zieba, Jennifer, 803B Zimmerman, Sandra G., 200B* Zintel, Trisha, 602B Zintel, Trisha M., 340A, 348C, 350B*, 608B Zinzen, Robert P., 747C, 753C, 765C Zirin, Jonathan, 69 Ziukaite, Ruta, 108, 710B* Zografos, Lysimachos, 618C Zong, Yan, 256A Zubair, Asif, 640A Zulueta-Coarasa, Teresa, 210C* Zuniga, Gabrielle, 259A Zuo, Zach, 158B Zurovec, Michal, 4*

103

KEYWORD INDEX

The following index is composed of keywords selected by presenting authors from a list on the Abstract Submission Site. Abstract program numbers follow each keyword.

Cell Biology and Cytoskeleton morphogens necrosis 93 252C 274A cell adhesion 46 204C 205A 206B 207C 208A 209B notch transcriptional regulation 210C 97 230B 231C 232A 233B 234C 26 270C 271A 272B

other signaling cell polarity Cell Division and Growth 48 181A 182B 183C 184A 185B 186C 91 95 243C 244A 245B 246C 247A 187A 188B 189C 248B 249C 250A 251B Control

receptor tyrosine kinase/phosphatase cytoskeleton autophagy 94 235A 236B 237C 238A 239B 240C 49 50 52 112 114 157A 158B 159C 316A 241A 160A 161B 162C 163A 164B 165C

166A 167B 168C 169A 170B 171C cell competition stress 172A 173B 174C 175A 176B 177C 305B 306C 307A 308B 309C 258C 178A 179B 180C

cell growth tgfbeta endocytosis 4 289A 290B 291C 292A 293B 294C 117 224B 225C 226A 227B 228C 229A 113 193A 194B 195C 196A 295A

wingless endoplasmic reticulum centrosome 96 218B 219C 220A 221B 222C 223A 116 2 286A 287B

zinc extracellular matrix cytokinesis 257B 201C 202A 203B 3 8 288C

intracellular transport Cell Cycle and Cell Death meiosis 31 51 115 190A 191B 192C 280A 281B 282C 283A 284B 285C

apoptosis live imaging 275B mitosis 47 211A 212B 213C 214A 278B 279C

autophagy migration 273C muscle development 197B 198C 199A 200B 317B

caspases muscle attachment 29 regeneration 215B 310A 311B 312C 313A 314B 315C checkpoint Cell Biology and Signal Transduction 260B tissue growth 5 118 296B 297C 298A 299B 300C death mutants/genes autophagy 28 30 267C 268A tumor suppressors and oncogenes 259A 1 6 301A 302B 303C 304A

developmental modulation canalization/robustness 27 261C 253A Chromatin and Epigenetics

DNA repair cell polarity 262A chromatin assembly 254B 63 66 781A 782B 783C

DNA replication hedgehog 263B 264C 265A 266B chromatin structure 216C 217A 130 775A 776B 777C 778A 779B 780C

growth hippo 276C cytosine hydroxymethylation 92 62

inhibitors of apoptosis (iaps) insulin receptor 269B DNA methylation 256A 819C

innate immunity JAK/STAT 277A DNA replication 242B 821B 823A

kinase/phosphatase/cyclin morphogenesis 25 dosage compensation 255C 814A 815B

104

KEYWORD INDEX genome instability drug discovery k-12 curriculum 65 604A 886A 887B heterochromatin epilepsy 61 126 127 790A 791B 792C 793A 104 Evolution and Quantitative 794B 795C 796A 797B 798C 799A Genetics frailty histone variants and modifications 615C chromosome structural variation 786C 787A 788B 789C 35 648C 649A 650B hypoxia insulators/boundary elements 616A ecological Adaptations in Drosophila 64 800B 801C 802A 803B 804C Species intestinal dysbiosis 702C nuclear organization 98

817A epistasis metabolism 695B pairing/transvection 606C 607A 608B 609C 610A 611B

816C 612C evolution and development

36 37 651C 652A 653B 654C 655A polycomb/trithorax complexes mitochondrial disorders 656B 657C 658A 659B 660C 661A 60 805A 806B 807C 808A 809B 810C 614B 662B 663C 664A 665B 666C 667A 811A 812B 813C

nerve injury evolutionary parasitology remodeling complexes 621C 699C 784A 785B

neural degeneration fitness RNA epigenetic memory 100 102 119 122 125 556A 557B 558C 686B 818B 559A 560B 561C 562A 563B 564C

565A 566B 567C 568A 569B 570C genome evolution telomere 571A 572B 573C 574A 575B 576C 32 33 34 626B 627C 628A 629B 630C 822C 577A 578B 579C 580A 581B 582C 631A 632B 633C 634A 583A 584B 585C 586A 587B 588C telomere capping 589A 590B 591C 592A 593B genome-wide association 824B 697A non neuronal degeneration transposable element regulation 625A genotype-by-environment interaction 820A 692B 693C 694A obesity

101 121 594C 595A 596B phylogenetics Drosophila Models of Human 684C 685A Diseases oxidative stress

613A physiology addiction 700A 701B polycystic kidney disease 541A 619A population variation alcohol sensitivity 57 58 635B 636C 637A 638B 639C renal disease 623B 640A 641B 642C 643A 644B 645C 617B 646A 647B anxiety and depression skeletal muscle, aggregation, muscle 622A quantitative traits metabolism 53 54 55 668B 669C 670A 671B 672C 620B behaviour 673A 674B 675C 676A 677B 678C

618C 679A skeletal muscle, proteostasis,

glycophagy cancer recombination 624C 99 103 123 124 542B 543C 544A 545B 698B

546C 547A 548B small RNAs selection 605B cardiovascular disease 59 687C 688A 689B 690C 691A 549C 550A 551B 552C 553A 554B Educational Initiatives speciation developmental disorders 38 680B 681C 682A 683B 597C 598A 599B 600C 601A 602B 603C college/university curriculum systems biology 888C 889A 696C diabetes 120 555C genome projects transcriptome evolution 890B 891C 703A

105

KEYWORD INDEX

Gametogenesis and microbiota homones Organogenesis 136 499A

Wolbachia hormones cell differentiation 464B 465C 466A 512B 513C 514A 515B 516C 402C ion channels cell migration Neural Development 500B 501C 23 24 409A 410B axon guidance learning/memory ectodermal derivatives 10 467B 468C 469A 470B 148 505A 506B 507C 407B 408C CNS locomotion/flight endodermal derivatives 16 488B 489C 490A 491B 492C 493A 523A 524B 404B 494B magnetic orientation gene expression dendrites 539B 413B 11 471C 472A 473B 474C 475A malpighian tubules germline stem cell niche glia 540C 412A 485B 486C 487A mechanosensation live imaging neuroblasts 147 525C 411C 495C neurotransmitters mesodermal derivatives neuronal morphogenesis 496A 497B 498C 21 22 405C 406A 15 482B 483C 484A olfaction oogenesis neuronal specification 527B 528C 529A 530B 531C 18 20 384C 385A 386B 387C 388A 9 479B 480C 481A 389B 390C 391A 392B 393C 394A pharmacology 395B 396C synaptogenesis 536B 12 13 14 476B 477C 478A ovulation seizures 414C 537C Neurophysiology and pre-gametogenic germ cell Behavior synaptic function development 502A 503B 504C 397A aggression sex determination 511A Pattern Formation 398B 399C 400A behavior axis specification 538A sex-specific traits and molecules 39 40 704B 705C 706A 707B 708C

401B 709A 710B chemosensation

526A somatic cell differentiation canalization/robustness

403A 44 circadian rhythms

144 510C spermatogenesis compartments and boundaries

17 370A 371B 372C 373A 374B 375C 45 711C circuits 376A 377B 378C 379A 380B 381C 145 534C 535A 382A 383B eye disc

712A 713B 714C cold nociception

Immunity and Pathogenesis 143 leg disc

719B courtship and mating cellular immunity 142 508A 509B 138 448A 449B 450C muscle pattern

721A feeding behavior host/pathogen interaction 146 518B 519C 520A 521B 522C 135 140 461B 462C 463A networks

43 grooming behavior humoral immunity 517A 451A oogenesis

722B gustation innate immunity 141 532A 533B 133 134 137 139 452B 453C 454A 455B predictive modelling

456C 457A 458B 459C 460A 720C

106

KEYWORD INDEX wing disc RNA binding proteins short ORF coding gene in 41 42 715A 716B 717C 718A 837C transcriptional control 772A RNA export Physiology, Organismal Growth, and 850A splicing regulation Aging 769A RNA localization developmental timing 838A 839B transcription 369C initiation/elongation/termination rnase P RNA 732C 733A dietary restriction 86 351C siRNA/RNAi Stem Cells endocrine function 90 832A 833B 834C 343A 344B 345C 346A 347B 348C blood stem cells 349A 350B splicing and its regulation 444C 842B 843C 844A 845B 846C hypoxia cell competition 366C stability/turnover 445A 447C 84 85 840C 841A insulin signaling follicle stem cell 67 71 357C 358A 359B 360C 361A translation and its regulation 154 415A 362B 87 88 847A 848B 849C germline stem cell intestinal mutualism Regulation of Gene Expression 155 156 416B 417C 418A 419B 420C 368B 421A metabolism activators/coactivators gut stem cells 19 68 69 72 73 327C 328A 329B 330C 734B 735C 151 152 435C 436A 437B 438C 439A 331A 332B 333C 334A 335B 440B 441C 442A 443B alternative splicing microbiota 773B hematopoietic progenitor cells 367A 446B core promoters and general nutrient sensing transcription factors neural stem cells 337A 338B 339C 340A 341B 342C 105 723C 724A 725B 726C 727A 728B 149 150 432C 433A 434B 729C 730A 731B nutrition niche and other local signaling 56 336C dosage compensation 153 422B 423C 424A 425B 426C 427A 771C 428B 429C olfaction 74 enhancers systemic factors 106 128 129 132 740B 741C 742A 743B 430A 431B p38MAPK controls myoproteostasis 744C 745A 746B 747C 748A 749B 364A 750C 751A 752B 753C 754A 755B 756C 757A 758B 759C 760A 761B Techniques and Resources physiology of adult organs 352A 353B 354C 355A 356B gene model annotation computational algorithms

767B 774C 865A 866B regeneration

7 363C ligand genes databases

766A 871A reproductive senescence

365B MZT , ASE epitope labeling

770B 878B stress response

70 318C 319A 320B 321C 322A 323B pattern formation gene disruption and targeting 324C 325A 326B 107 108 109 131 762C 763A 764B 765C 75 76 77 78 79 82 856A 857B 858C

RNA Biology post translational modification high-throughput phenotyping 768C 81 864C long non-coding RNAs quantitative measurement imaginal disc 83 835A 836B 110 884B miRNA repressors/corepressors microarrays 825C 826A 827B 828C 829A 111 736A 737B 738C 739A 859A piRNA 89 830B 831C

107

KEYWORD INDEX microscopy 851B 852C 853A 854B molecular interactions 875B morphometric analysis 882C neural circuits 883A next-generation sequencing 860B 861C 862A 863B phic31 transgenesis 80 recombination systems 872B 873C 874A resources 881B rho1, temperature sensitive allele 876C

RNAi 855C spaceflight 877A species survey 879C stocks 885C transgenesis vectors 880A webtools 867C 868A 869B 870C

108

FLYBASE GENETIC INDEX TO ABSTRACTS

This is an index of genes mentioned in the abstracts. The current FlyBase-approved gene symbol is given in each case; non-current symbol synonyms or full names used in the abstracts are not indexed.

The index was prepared computationally based solely on the FBgn & gene symbol information provided by authors during abstract submission. FlyBase has performed a cross-check between the FBgn and gene symbol provided to ensure the intended gene is indexed. FlyBase is not responsible for any omissions from the index where authors did not provide information, nor for any incorrect indexing where genes stated to feature in an abstract do not actually appear.

Indexed terms are in bold. Numbers following each term refer to abstract program numbers: 1--156 are platform presentations and 157 and beyond are poster presentations.

14-3-3ε ...... 279C c(3)G ...... 284B 656B Crag ...... 254B α-Spec ...... 429C Ca-P60A ...... 327C crb ...... 183C 185B 407B abd-A ...... 267C cact ...... 82 91 720C CrebA ...... 561C Abd-B ...... 761B Cad96Ca ...... 241A cry ...... 344B Abl ...... 163A 166A Cad99C ...... 407B CS-2 ...... 413B Ack ...... 235A cal1 ...... 783C CtBP ...... 739A Acn ...... 259A CalpA ...... 91 CTCF ...... 800B Acp26Aa ...... 401B 513C Cap ...... 281B 285C ctp ...... 258C Acp36DE ...... 401B caps ...... 93 CTPsyn ...... 393C Act5C ...... 202A cas ...... 757A cu ...... 349A Actβ ...... 69 444C 499A 891C Cat ...... 613A Cul-3 ...... 114 Actn ...... 167B caup ...... 660C cv ...... 225C Adgf-A ...... 4 135 Cbl ...... 393C cv-c ...... 225C AdipoR ...... 156 Cdc42 ...... 187A CycB ...... 279C AdoR ...... 4 135 CDC45L...... 823A Cyp12d1-d ...... 54 AGO2 ...... 90 100 776B Ced-12 ...... 30 187A Cyp12d1-p ...... 54 AGO3 ...... 831C CG10126 ...... 293B d ...... 118 Akt1 ...... 71 357C CG11864 ...... 401B da ...... 151 726C ald ...... 279C CG12320 ...... 345C Dana\GF12453 ...... 637A aly ...... 383B CG13442 ...... 371B Dana\GF12772 ...... 637A ap ...... 42 743B CG14207 ...... 324C Dana\GF17434 ...... 637A Apc ...... 447C CG14962 ...... 258C Dana\GF18428 ...... 637A Apc2 ... 219C 223A 429C 447C CG1667 ...... 454A Dana\GF22451 ...... 637A aPKC ...... 182B CG16758 ...... 319A Dana\GF25200 ...... 637A apt ...... 427A CG1737 ...... 796A Dana\nos ...... 637A ara ...... 660C Cg25C ...... 225C dbb ...... 563B Ark ...... 29 CG32016 ...... 891C dco ...... 303C arm ...... 219C CG32088 ...... 283A Dcp-1 ...... 268A 273C armi ...... 797B CG3499 ...... 125 Dcr-1 ...... 11 ast ...... 391A CG4078 ...... 262A 797B dgrn ...... 61 Atg1 ...... 620B CG4221 ...... 118 Dhc64C ...... 21 171C 192C aub ...... 831C CG43444 ...... 62 dia ...... 41 93 186C 429C Axn ...... 219C CG4500 ...... 563B dl ..... 91 108 704B 707B 720C babo ...... 69 CG4552 ...... 408C 741C 759C baf ...... 18 CG5210 ...... 200B Dl ...... 231C 405C 652A ban ...... 28 CG6701 ...... 797B Dlc90F ...... 162C baz ...... 172A CG6767 ...... 527B dlg1 ...... 255C bcd .. 36 44 105 107 110 805A CG7261 ...... 484A Dll ...... 42 bgm ...... 563B CG7813 ...... 381C dlp ...... 222C bigmax ...... 337A CG8108 ...... 798C dm ...... 153 245B Blimp-1 ...... 369C CG9281 ...... 706A dock ...... 235A Blm ...... 262A 266B CG9996 ...... 231C dop ...... 197B bmm...... 72 Chd1 ...... 63 785B 817A dor ...... 30 bnl ...... 23 cher ...... 167B dpp ...... 42 93 117 128 225C br ...... 389B CHES-1-like ...... 405C 226A 253A 420C 660C 704B brat ...... 149 chic ...... 373A 718A 720C 759C brk ...... 42 253A 660C CHIP ...... 324C Dpt ...... 59 brm ...... 149 813C Chro ...... 796A Drak ...... 161B bru-3 ...... 53 ci ...... 128 891C drk ...... 241A Bsg25D ...... 213C cic ...... 94 437B 736A Drp1 ...... 12 550A 624C bsk ...... 21 30 240C 253A cid ...... 783C drpr ...... 30 187A 576C 309C 544A 836B Clamp ...... 815B ds ...... 40 48 118 Btk29A ...... 241A clu ...... 51 Dscam1 ...... 484A btl ...... 23 coil ...... 815B dsx ...... 398B 399C 659B bwk ...... 200B comr ...... 383B 662B 750C 761B 844A by ...... 208A cona ...... 656B dve ...... 713B c(2)M ...... 281B 656B cora ...... 255C 475A Dyak\GE13145 ...... 632B

109

FLYBASE GENETIC INDEX TO ABSTRACTS

Dyak\GE17463 ...... 632B gt ...... 805A Mcm10 ...... 264C 265A Dyak\GE20773 ...... 632B Gyc76C ...... 225C Mcr ...... 255C Dyak\GE21054 ...... 632B H15 ...... 705C Med ...... 42 704B Dyak\GE25391 ...... 632B hb ...... 107 110 732C 805A MED1 ...... 734B Dyak\GE25985 ...... 632B HDAC4 ...... 72 MED31 ...... 734B Dyak\GE25995 ...... 632B Hdc ...... 878B Mef2 ...... 749B E(bx) ...... 545B hh ...... 41 128 217A mei-41 ...... 26 88 E(spl)mα-BFM ...... 740B Him ...... 405C Met ...... 343A 346A E(z) ...... 805A HipHop ...... 822C mid ...... 705C eas ...... 537C hoip ...... 837C Mio ...... 337A 354C Eb1 ...... 49 200B hop ...... 99 705C 739A mip120 ...... 781A ecd ...... 345C HP1b ...... 780C mip40 ...... 383B EcR ...... 302B HP1c ...... 780C Mipp1 ...... 23 ed ...... 172A HP1e ...... 126 mir-2a-1 ...... 261C Efr ...... 232A hpo ...... 92 308B mir-310 ...... 352A Egfr ...... 293B Hr4 ...... 349A mir-311 ...... 352A egl ...... 192C Hsap\APP ...... 589A mir-312 ...... 352A egr ...... 315C Hsap\TARDBP ...... 591C mir-313 ...... 352A eIF-4a ...... 250A hts ...... 175A mirr ...... 195C 758B Eip78C ...... 384C htt ...... 593B 620B Mmp1 ...... 203B 298A 414C emc ...... 726C Ice ...... 29 268A Mmp2 ...... 222C 225C 414C en ...... 745A 808A ics ...... 168C mmy ...... 228C ena ...... 52 162C 163A 169A Idgf3 ...... 200B mnb ...... 502A Ent2 ...... 4 Idgf4 ...... 200B Msp-300 ...... 49 erm ...... 149 Idgf5 ...... 200B Mst77F ...... 370A esg ...... 271A, 418A if ...... 250A mt:CoI ...... 643A eve ...... 107 734B 764B 801C Ilk ...... 208A Mtor ...... 279C exo70 ...... 194B Ilp2 ...... 120 mud ...... 288C exo84 ...... 194B Ilp6 ...... 153 Mul1 ...... 568A ey ...... 804C Ilp8 ...... 297C mwh ...... 186C eyg ...... 261C Ino80 ...... 737B 807C Myb ...... 405C 545B eys ...... 202A InR ...... 67 Myo31DF ...... 40 211A Fak ...... 165C inv ...... 808A mys ...... 95 165C 174C 187A fd102C ...... 891C Ire1 ...... 15 205A 208A 250A fd64A ...... 410B Irk2 ...... 226A N ...... 42 97 140 153 231C fj ...... 48 ix ...... 734B 232A 234C 261C 267C 405C fkh ...... 151 Jheh1 ...... 686B 459C 506B 652A 706A 741C flw ...... 169A Jheh2 ...... 686B 759C fne ...... 475A JIL-1 ...... 789C nab ...... 42 fog ...... 46 Jra ...... 246C nac ...... 232A fon ...... 215B jumu ...... 405C Nc ...... 29 268A for ...... 225C Jupiter ...... 253A Ncc69 ...... 501C foxo .... 357C 474C 589A 728B kay ...... 187A Ndg ...... 405C fray ...... 501C kel ...... 114 429C nes ...... 379A fru ...... 508A Khc ...... 21 171C neur ...... 529A ft ...... 48 118 kkv ...... 413B Nhe2 ...... 123 ftz ...... 734B kn ...... 660C Nipped-B ...... 281B ftz-f1 ...... 369C kni ...... 716B 805A Nmdar1 ...... 569B fu ...... 216C kon ...... 174C nmo ...... 14 fuss ...... 492C 891C Kr ...... 732C 734B 805A nonC ...... 85 futsch ...... 847A l(1)G0156 ...... 588C Nos ...... 297C fz ...... 189C l(2)efl ...... 721A NPF ...... 344B fzy ...... 274A 279C l(2)gl ...... 302B 458B NPFR ...... 344B G9a ...... 134 Lam ...... 18 395B Nrg ...... 93 Gαf ...... 99 LamC ...... 610A Nrx-IV ...... 255C 475A garz ...... 163A LanB2 ...... 225C Ntf-2r ...... 655A gbb ...... 14 lea ...... 468C nub ...... 757A gce ...... 343A 346A lid ...... 728B 787A nuf ...... 182B Gdi ...... 247A lkb1 ...... 72 numb ...... 149 Git ...... 165C lok ...... 18 88 420C 822C Nup98-96 ...... 313A Gli ...... 255C lola ...... 406A nwk ...... 14 GluRIIA ...... 14 lov ...... 518B Nxt1 ...... 850A GMR ...... 598A Lsd-2 ...... 595A oc ...... 105 gpp ...... 399C Mad .... 14 42 224B 229A 426C odd ...... 489C Grasp65 ...... 51 704B orb ...... 848B grim ...... 267C 268A mad2 ...... 279C 392B ord ...... 281B 656B grk ...... 88 239B 388A 848B Marcal1 ...... 601A org-1 ...... 22 849C 875B Marf ...... 12 osa ...... 813C gro ...... 734B 736A mbc ...... 204C osk ...... 805A GS ...... 613A mbt ...... 433A Ote ...... 18

110

FLYBASE GENETIC INDEX TO ABSTRACTS oys ...... 379A robo3 ...... 468C snRNA:U6:96Ab ...... 731B p38b ...... 324C 364A Roc2 ...... 16 snRNA:U6:96Ac ...... 731B p53 ...... 274A 822C rok ...... 50 Socs36E ...... 427A pain ...... 147 RpA-70 ...... 26 Sod ..... 322A 550A 613A 624C Pak3 ...... 576C RpL22 ...... 378C sog ...... 720C Pal2 ...... 147 RpL22-like ...... 378C spas ...... 576C pan ...... 891C RpL7A ...... 250A spen ...... 435C para ...... 147 rpr ...... 29 267C 268A spg ...... 204C park ...... 568A 575B RpS3 ...... 307A 445A spir ...... 176B pasha ...... 11 RpS3A ...... 891C spn-B ...... 388A 391A Pax ...... 195C rti ...... 3 spok ...... 345C Pc ...... 60 805A 811A rumi ...... 231C spz ...... 305B 707B PCNA ...... 799A ry ...... 613A sqd ...... 848B 875B pcx ...... 234C RyR ...... 327C sqh ...... 46 161B 179B 202A Pdk1...... 71 S ...... 391A sr ...... 128 pdm2 ...... 757A S6k ...... 620B Src42A ...... 97 241A PDZ-GEF ...... 236B SA ...... 281B Src64B ...... 8 97 241A peb ...... 414C sage ...... 356B ss ...... 131 phm ...... 409A salm ...... 23 716B 758B stan ...... 189C pho ...... 805A 807C salr ...... 716B Stat92E .... 99 427A 705C 739A Pi3K92E ...... 71 santa-maria ...... 458B stau ...... 44 Piezo ...... 147 Sas ...... 555C stck ...... 168C Pink1 ...... 568A sas ...... 407B stg ...... 443B Pis ...... 254B sca ...... 506B sti ...... 280A piwi ...... 377B SCAR ...... 41 stv ...... 324C pk ...... 48 104 scb ...... 187A 205A Su(H) ...... 42 128 405C 652A pnt ...... 600C Scr ...... 659B 750C 706A 739A 759C polo ...... 405C scrib ...... 309C su(Hw) ...... 800B Poxn...... 659B SdhB ...... 614B su(s) ...... 84 ppk ...... 147 sec10 ...... 194B Su(var)20561 780C 798C 799A prom ...... 202A sec15 ...... 140 194B Su(var)3-9 ...... 789C pros ...... 150 sec3 ...... 194B SuUR ...... 823A Prp8 ...... 345C sec5 ...... 194B sv ...... 128 ptc ...... 41 128 sec6 ...... 194B svp ...... 67 758B Pten ...... 474C sec8 ...... 194B sxc ...... 248B Ptpmeg ...... 569B Seipin ...... 327C Sxl ...... 400A 812B Pvf1 ...... 240C 882C Sema-2a ...... 410B syd ...... 21 Pvr ...... 240C 882C Sema-5c ...... 529A synj ...... 502A Pxt ...... 52 Ser ...... 231C Syt1 ...... 504C PyK ...... 88 sesB ...... 273C Syx7 ...... 302B pzg ...... 796A sev ...... 236B tai ...... 346A R ...... 236B sff ...... 16 tau ...... 550A 624C Rab1 ...... 247A sgg ...... 583A Tbp ...... 731B Rab10 ...... 20 278B shark ...... 200B TBPH ...... 100 Rab11 ...... 117 140 247A shd ...... 409A Tdc2 ...... 144 Rab23 ...... 352A shg ...... 46 140 198C TER94 ...... 801C Rab35 ...... 117 247A shi ...... 93 195C th ...... 29 424A Rab5 ...... 30 shot ...... 49 Thd1 ...... 891C Rab7 ...... 30 117 503B Sik3 ...... 72 Tie ...... 28 Rab8 ...... 158B sima ...... 616A Tig ...... 215B Rac2...... 200B Sin3A ...... 762C 787A Timp ...... 225C Rack1 ...... 90 364A sing ...... 749B Tis11 ...... 441C Ran ...... 279C Skeletor ...... 258C tj ...... 412A Ran-like ...... 655A skl ...... 268A tko ...... 537C raptor ...... 338B sktl ...... 376A tkv ...... 252C 253A 660C 704B Ras85D ...... 309C 458B 874A sl ...... 238A Tl ...... 71 91 707B 720C raw ...... 246C 836B sli ...... 468C tll ...... 734B Rcd-1r ...... 34 slp1 ...... 752B Tm1 ...... 160A 200B RecQ4 ...... 265A slpr ...... 882C Tm2 ...... 837C ref(2)P ...... 324C SMC1 ...... 281B Tollo ...... 16 Rfabg ...... 595A 891C Smc5 ...... 61 797B tomb ...... 383B Rh3 ...... 131 Smg5 ...... 85 tor ...... 39 708C Rh4 ...... 131 Smg6 ...... 85 Tor ...... 465C 620B rhea ...... 95 205A 207C 208A Smn ...... 592A toy ...... 891C Rho1 ...... 50 99 280A 876C smo ...... 216C 217A Tpl94D ...... 370A RhoGDI ...... 200B 617B Smox ...... 69 444C TpnC41C ...... 744C rib ...... 406A smt3 ...... 61 tra ...... 844A rictor ...... 71 sna ...... 271A 418A 720C tra2 ...... 844A rl ...... 94 Snr1 ...... 813C Trap1 ...... 550A 624C robo ...... 468C snRNA:U6:96Aa ...... 731B trbl ...... 291C 357C

111

FLYBASE GENETIC INDEX TO ABSTRACTS

Trf ...... 731B trk ...... 39 Trl ...... 803B trol ...... 225C 416B Tsc1 ...... 338B tsl ...... 39 708C 805A tsr ...... 280A ttk ...... 195C tud ...... 397A Tudor-SN ...... 377B tup ...... 22 twi ...... 741C 759C Ube3a ...... 598A 599B 603C uif ...... 298A Upf1...... 85 Upf2...... 85 Upf3...... 85 Vang ...... 189C vap ...... 600C vfl ...... 26 42 108 132 754A Vhl ...... 616A vkg ...... 20 vn ...... 660C 718A vtd ...... 281B W ...... 268A Wdr82 ...... 84 wg ...... 96 128 302B 309C 363C 544A 583A 718A whd ...... 613A wisp ...... 848B Wnk ...... 501C wor ...... 271A wts ...... 4 wuc ...... 383B wupA ...... 290B x16 ...... 844A Xbp1 ...... 15 Ybb ...... 65 yki .... 92 118 251B 309C 544A yrt ...... 475A zfh1 ...... 426C Zfrp8 ...... 62 zip ...... 46 50 202A Zip42C.1 ...... 257B Zip42C.2 ...... 257B Zip88E ...... 257B Zip89B ...... 257

112

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