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SKU# Product Description TP300009 Recombinant Protein of Human

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SKU# Product description TP300009 Recombinant protein of human protein phosphatase methylesterase 1 (PPME1) TP300010 Recombinant protein of human small nuclear ribonucleoprotein 25kDa (U11/U12) (SNRNP25) TP300016 Recombinant protein of human chromosome 14 open reading frame 166 (C14orf166) TP300018 Recombinant protein of human leucine carboxyl methyltransferase 1 (LCMT1), transcript variant 1 TP300019 Recombinant protein of human HMP19 protein (HMP19) TP300033 Recombinant protein of human mitochondrial ribosomal protein L11 (MRPL11), nuclear gene encoding mitochondrial protein, transcript variant 1 TP300035 Recombinant protein of human exosome component 3 (EXOSC3), transcript variant 1 TP300036 Recombinant protein of human hypothetical protein HSPC152 (HSPC152) TP300049 Recombinant protein of human transmembrane protein 208 (TMEM208) TP300051 Recombinant protein of human dynein, light chain, roadblock-type 1 (DYNLRB1) TP300052 Recombinant protein of human mitochondrial ribosomal protein L18 (MRPL18), nuclear gene encoding mitochondrial protein TP300054 Recombinant protein of human ribosomal protein L36 (RPL36), transcript variant 2 TP300055 Recombinant protein of human methyltransferase like 11A (METTL11A) TP300071 Recombinant protein of human spastic paraplegia 21 (autosomal recessive, Mast syndrome) (SPG21), transcript variant 1 TP300076 Recombinant protein of human dysbindin (dystrobrevin binding protein 1) domain containing 2 (DBNDD2), transcript variant 1 TP300079 Recombinant protein of human SCAN domain containing 1 (SCAND1), transcript variant 2 TP300091 Recombinant protein of human zinc finger protein 581 (ZNF581) TP300093 Recombinant protein of human TTK protein kinase (TTK) TP300099 Recombinant protein of human COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) (COX16) TP300102 Recombinant protein of human linker for activation of T cells family, member 2 (LAT2), transcript variant 2 TP300104 Recombinant protein of human aspartyl aminopeptidase (DNPEP) TP300129 Recombinant protein of human chromosome 12 open reading frame 11 (C12orf11) TP300130 Recombinant protein of human DnaJ (Hsp40) homolog, subfamily C, member 17 (DNAJC17) TP300132 Recombinant protein of human REC8 homolog (yeast) (REC8), transcript variant 1 TP300140 Recombinant protein of human ankyrin repeat and zinc finger domain containing 1 (ANKZF1), transcript variant 2 TP300142 Recombinant protein of human WD repeat containing, antisense to TP53 (WRAP53), transcript variant 1 TP300145 Purified recombinant protein of Homo sapiens LAG1 homolog, ceramide synthase 2 (LASS2), transcript variant 2 TP300158 Recombinant protein of human PIH1 domain containing 1 (PIH1D1) TP300160 Recombinant protein of human chromosome 9 open reading frame 95 (C9orf95), transcript variant 1 TP300163 Recombinant protein of human zinc finger protein 692 (ZNF692), transcript variant 2 TP300164 Recombinant protein of human chromosome 1 open reading frame 56 (C1orf56) TP300165 Recombinant protein of human gem (nuclear organelle) associated protein 8 (GEMIN8), transcript variant 2 TP300169 Recombinant protein of human chromosome 21 open reading frame 59 (C21orf59) TP300178 Recombinant protein of human F-box and leucine-rich repeat protein 12 (FBXL12) TP300203 Purified recombinant protein of Homo sapiens copine I (CPNE1), transcript variant 7 TP300210 Recombinant protein of human aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) (AKR1C3) TP300216 Recombinant protein of human DnaJ (Hsp40) homolog, subfamily B, member 11 (DNAJB11) TP300217 Recombinant protein of human GTP binding protein 6 (putative) (GTPBP6) TP300221 Recombinant protein of human cellular retinoic acid binding protein 2 (CRABP2) TP300235 Recombinant protein of human programmed cell death 10 (PDCD10), transcript variant 1 TP300237 Recombinant protein of human protein kinase C and casein kinase substrate in neurons 2 (PACSIN2) TP300238 Recombinant protein of human chromosome 14 open reading frame 1 (C14orf1) TP300239 Recombinant protein of human transmembrane protein 14B (TMEM14B), transcript variant 1 TP300240 Recombinant protein of human ubiquitin-conjugating enzyme E2C (UBE2C), transcript variant 4 TP300241 Recombinant protein of human SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) (SUMO3) TP300243 Recombinant protein of human RUN and SH3 domain containing 1 (RUSC1), transcript variant 4 TP300246 Recombinant protein of human UDP-glucose pyrophosphorylase 2 (UGP2), transcript variant 2 TP300249 Recombinant protein of human RAB31, member RAS oncogene family (RAB31) TP300252 Recombinant protein of human COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) (COPS6) TP300256 Recombinant protein of human UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) TP300260 Recombinant protein of human YKT6 v-SNARE homolog (S. cerevisiae) (YKT6) TP300267 Recombinant protein of human COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) (COPS8), transcript variant 2 TP300276 Recombinant protein of human HIV-1 Tat interactive protein 2, 30kDa (HTATIP2), transcript variant 2 TP300279 Recombinant protein of human polymerase (RNA) III (DNA directed) polypeptide C (62kD) (POLR3C) TP300280 Recombinant protein of human protein phosphatase 1, regulatory (inhibitor) subunit 2 (PPP1R2) TP300289 Recombinant protein of human ATG4 autophagy related 4 homolog B (S. cerevisiae) (ATG4B), transcript variant 1 TP300290 Recombinant protein of human tuftelin interacting protein 11 (TFIP11), transcript variant 1 TP300291 Recombinant protein of human TEL2, telomere maintenance 2, homolog (S. cerevisiae) (TELO2) TP300302 Recombinant protein of human aldo-keto reductase family 1, member A1 (aldehyde reductase) (AKR1A1), transcript variant 1 TP300303 Recombinant protein of human WD repeat domain 1 (WDR1), transcript variant 1 TP300307 Recombinant protein of human Ras homolog enriched in brain (RHEB) TP300317 Recombinant protein of human DiGeorge syndrome critical region gene 6-like (DGCR6L) TP300321 Recombinant protein of human angiopoietin-like 7 (ANGPTL7) TP300334 Recombinant protein of human family with sequence similarity 32, member A (FAM32A) TP300344 Recombinant protein of human thioredoxin-like 1 (TXNL1), transcript variant 1 TP300353 Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) (PSMB8), transcript variant 1 TP300356 Recombinant protein of human nucleolar and coiled-body phosphoprotein 1 (NOLC1) TP300361 Recombinant protein of human general transcription factor IIF, polypeptide 2, 30kDa (GTF2F2) TP300368 Recombinant protein of human eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1) TP300369 Recombinant protein of human enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1), nuclear gene encoding mitochondrial protein TP300383 Recombinant protein of human retinoic acid receptor responder (tazarotene induced) 2 (RARRES2) TP300385 Recombinant protein of human uroporphyrinogen III synthase (UROS) TP300389 Recombinant protein of human torsin family 1, member A (torsin A) (TOR1A) TP300398 Purified recombinant protein of Homo sapiens four and a half LIM domains 2 (FHL2), transcript variant 4 TP300400 Recombinant protein of human zinc finger protein 174 (ZNF174), transcript variant 2 TP300403 Recombinant protein of human coronin, actin binding protein, 2A (CORO2A), transcript variant 1 TP300405 Recombinant protein of human vesicle-associated membrane protein 8 (endobrevin) (VAMP8) TP300409 Recombinant protein of human tumor suppressing subtransferable candidate 1 (TSSC1) TP300414 Recombinant protein of human structure specific recognition protein 1 (SSRP1) TP300423 Recombinant protein of human ribosomal protein L38 (RPL38), transcript variant 2 TP300425 Recombinant protein of human ribosomal protein L14 (RPL14), transcript variant 2 TP300432 Recombinant protein of human RAB6A, member RAS oncogene family (RAB6A), transcript variant 1 TP300446 Recombinant protein of human oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (OGDH), nuclear gene encoding mitochondrial protein, transcript variant 1 TP300454 Recombinant protein of human megakaryocyte-associated tyrosine kinase (MATK), transcript variant 3 TP300471 Recombinant protein of human GDP-mannose 4,6-dehydratase (GMDS) TP300501 Recombinant protein of human ADP-ribosylation factor-like 2 (ARL2) TP300507 Recombinant protein of human adrenomedullin (ADM) TP300510 Recombinant protein of human HIRA interacting protein 3 (HIRIP3) TP300512 Recombinant protein of human calcium homeostasis modulator 2 (CALHM2), transcript variant 1 TP300515 Recombinant protein of human procollagen C-endopeptidase enhancer (PCOLCE) TP300520 Recombinant protein of human dynein, axonemal, light chain 4 (DNAL4) TP300525 Recombinant protein of human ribosomal protein S6 kinase, 70kDa, polypeptide 2 (RPS6KB2) TP300528 Recombinant protein of human guanidinoacetate N-methyltransferase (GAMT), transcript variant 1 TP300531 Recombinant protein of human dual specificity phosphatase 14 (DUSP14) TP300535 Purified recombinant protein of Homo sapiens leptin receptor overlapping transcript-like 1 (LEPROTL1), transcript variant 1 TP300537 Recombinant protein of human stanniocalcin 2 (STC2) TP300539 Recombinant protein of human calpain 6 (CAPN6) TP300545 Recombinant protein of human RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae) (RER1) TP300551 Recombinant protein of human 3'-phosphoadenosine 5'-phosphosulfate
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    REVIEW pubs.acs.org/CR The Metabolic Serine Hydrolases and Their Functions in Mammalian Physiology and Disease Jonathan Z. Long* and Benjamin F. Cravatt* The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States CONTENTS 2.4. Other Phospholipases 6034 1. Introduction 6023 2.4.1. LIPG (Endothelial Lipase) 6034 2. Small-Molecule Hydrolases 6023 2.4.2. PLA1A (Phosphatidylserine-Specific 2.1. Intracellular Neutral Lipases 6023 PLA1) 6035 2.1.1. LIPE (Hormone-Sensitive Lipase) 6024 2.4.3. LIPH and LIPI (Phosphatidic Acid-Specific 2.1.2. PNPLA2 (Adipose Triglyceride Lipase) 6024 PLA1R and β) 6035 2.1.3. MGLL (Monoacylglycerol Lipase) 6025 2.4.4. PLB1 (Phospholipase B) 6035 2.1.4. DAGLA and DAGLB (Diacylglycerol Lipase 2.4.5. DDHD1 and DDHD2 (DDHD Domain R and β) 6026 Containing 1 and 2) 6035 2.1.5. CES3 (Carboxylesterase 3) 6026 2.4.6. ABHD4 (Alpha/Beta Hydrolase Domain 2.1.6. AADACL1 (Arylacetamide Deacetylase-like 1) 6026 Containing 4) 6036 2.1.7. ABHD6 (Alpha/Beta Hydrolase Domain 2.5. Small-Molecule Amidases 6036 Containing 6) 6027 2.5.1. FAAH and FAAH2 (Fatty Acid Amide 2.1.8. ABHD12 (Alpha/Beta Hydrolase Domain Hydrolase and FAAH2) 6036 Containing 12) 6027 2.5.2. AFMID (Arylformamidase) 6037 2.2. Extracellular Neutral Lipases 6027 2.6. Acyl-CoA Hydrolases 6037 2.2.1. PNLIP (Pancreatic Lipase) 6028 2.6.1. FASN (Fatty Acid Synthase) 6037 2.2.2. PNLIPRP1 and PNLIPR2 (Pancreatic 2.6.2.
  • A Novel Keratin 12 Mutation in a German Kindred with Meesmann's

    A Novel Keratin 12 Mutation in a German Kindred with Meesmann's

    Br J Ophthalmol 2000;84:527–530 527 A novel keratin 12 mutation in a German kindred Br J Ophthalmol: first published as 10.1136/bjo.84.5.527 on 1 May 2000. Downloaded from with Meesmann’s corneal dystrophy L D Corden, O Swensson, B Swensson, R Rochels, B Wannke, H J Thiel, W H I McLean Abstract inherited disorder aVecting the corneal epithe- Aim—To study a kindred with Mees- lium of both eyes.1–3 It manifests in early child- mann’s corneal dystrophy (MCD) to de- hood and is characterised by myriads of termine if a mutation within the cornea intraepithelial microcysts of variable distribu- specific K3 or K12 genes is responsible for tion and density. The microcysts are best seen the disease phenotype. by retroillumination and slit lamp Methods—Slit lamp examination of the examination.45 Further clinical signs of the cornea in four members of the kindred disease are recurrent punctate erosions with lacrimation and photophobia. Symptoms in- Epithelial Genetics was carried out to confirm the diagnosis Group, Human of MCD. The region encoding the helix clude blurred vision and foreign body sensa- Genetics Unit, initiation motif (HIM) of the K12 polypep- tion. Histologically, the corneal epithelium Department of tide was polymerase chain reaction (PCR) appears irregularly thickened and contains Molecular and Cellular amplified from genomic DNA derived numerous vacuolated suprabasal cells.6–8 In Pathology, Ninewells addition, there is intraepithelial cyst formation Medical School, from aVected individuals in the kindred. Dundee DD1 9SY PCR products generated were subjected to with accumulated periodic acid SchiV (PAS) L D Corden direct automated sequencing.