DOCSLIB.ORG

Antibodies Products

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Antibodies Products Chapter 2 : Gentaur Products List • Human Signal peptidase complex catalytic subunit • Human Sjoegren syndrome nuclear autoantigen 1 SSNA1 • Human Small proline rich protein 2A SPRR2A ELISA kit SEC11A SEC11A ELISA kit SpeciesHuman ELISA kit SpeciesHuman SpeciesHuman • Human Signal peptidase complex catalytic subunit • Human Sjoegren syndrome scleroderma autoantigen 1 • Human Small proline rich protein 2B SPRR2B ELISA kit SEC11C SEC11C ELISA kit SpeciesHuman SSSCA1 ELISA kit SpeciesHuman SpeciesHuman • Human Signal peptidase complex subunit 1 SPCS1 ELISA • Human Ski oncogene SKI ELISA kit SpeciesHuman • Human Small proline rich protein 2D SPRR2D ELISA kit kit SpeciesHuman • Human Ski like protein SKIL ELISA kit SpeciesHuman SpeciesHuman • Human Signal peptidase complex subunit 2 SPCS2 ELISA • Human Skin specific protein 32 C1orf68 ELISA kit • Human Small proline rich protein 2E SPRR2E ELISA kit kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal peptidase complex subunit 3 SPCS3 ELISA • Human SLAIN motif containing protein 1 SLAIN1 ELISA kit • Human Small proline rich protein 2F SPRR2F ELISA kit kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal peptide CUB and EGF like domain • Human SLAIN motif containing protein 2 SLAIN2 ELISA kit • Human Small proline rich protein 2G SPRR2G ELISA kit containing protein 2 SCUBE2 ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal peptide CUB and EGF like domain • Human SLAM family member 5 CD84 ELISA kit • Human Small proline rich protein 3 SPRR3 ELISA kit containing protein 3 SCUBE3 ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal recognition particle 14 kDa protein SRP14 • Human SLAM family member 6 SLAMF6 ELISA kit • Human Small proline rich protein 4 SPRR4 ELISA kit ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal recognition particle 19 kDa protein SRP19 • Human SLAM family member 7 SLAMF7 ELISA kit • Human Small subunit of serine palmitoyltransferase A ELISA kit SpeciesHuman SpeciesHuman C14orf147 ELISA kit SpeciesHuman • Human Signal recognition particle 54 kDa protein SRP54 • Human SLAM family member 8 SLAMF8 ELISA kit • Human Small subunit of serine palmitoyltransferase B ELISA kit SpeciesHuman SpeciesHuman C3orf57 ELISA kit SpeciesHuman • Human Signal recognition particle 68 kDa protein SRP68 • Human SLAM family member 9 SLAMF9 ELISA kit • Human Small subunit processome component 20 homolog ELISA kit SpeciesHuman SpeciesHuman UTP20 ELISA kit SpeciesHuman • Human Signal recognition particle 72 kDa protein SRP72 • Human SLC2A4 regulator SLC2A4RG ELISA kit • Human Small ubiquitin related modifier 1 SUMO1 ELISA kit ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal recognition particle 9 kDa protein SRP9 • Human SLIT and NTRK like protein 1 SLITRK1 ELISA kit • Human Small ubiquitin related modifier 2 SUMO2 ELISA kit ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal recognition particle receptor subunit alpha • Human SLIT and NTRK like protein 2 SLITRK2 ELISA kit • Human Small ubiquitin related modifier 3 SUMO3 ELISA kit SRPR ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal recognition particle receptor subunit beta • Human SLIT and NTRK like protein 3 SLITRK3 ELISA kit • Human Small ubiquitin related modifier 4 SUMO4 ELISA kit SRPRB ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal transducer and activator of transcription 5B • Human SLIT and NTRK like protein 4 SLITRK4 ELISA kit • Human Small VCP p97 interacting protein SVIP ELISA kit STAT5B ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signal transducing adapter molecule 1 STAM • Human SLIT and NTRK like protein 5 SLITRK5 ELISA kit • Human Smith Magenis syndrome chromosomal region ELISA kit SpeciesHuman SpeciesHuman candidate gene 5 protein SMCR5 ELISA kit SpeciesHuman • Human Signal transducing adapter molecule 2 STAM2 • Human SLIT and NTRK like protein 6 SLITRK6 ELISA kit • Human Smith Magenis syndrome chromosomal region ELISA kit SpeciesHuman SpeciesHuman candidate gene 7 protein SMCR7 ELISA kit SpeciesHuman • Human Signal transduction protein CBL C CBLC ELISA kit • Human Slit homolog 1 protein SLIT1 ELISA kit • Human Smith Magenis syndrome chromosomal region SpeciesHuman SpeciesHuman candidate gene 7 protein like SMCR7L ELISA kit • Human Signal induced proliferation associated 1 like • Human Slit homolog 3 protein SLIT3 ELISA kit SpeciesHuman protein 1 SIPA1L1 ELISA kit SpeciesHuman SpeciesHuman • Human Smith Magenis syndrome chromosomal region • Human Signal induced proliferation associated 1 like • Human SLIT ROBO Rho GTPase activating protein 1 candidate gene 8 protein SMCR8 ELISA kit SpeciesHuman protein 2 SIPA1L2 ELISA kit SpeciesHuman SRGAP1 ELISA kit SpeciesHuman • Human Smoothelin SMTN ELISA kit SpeciesHuman • Human Signal induced proliferation associated 1 like • Human SLIT ROBO Rho GTPase activating protein 2 • Human Smoothelin like protein 1 SMTNL1 ELISA kit protein 3 SIPA1L3 ELISA kit SpeciesHuman SRGAP2 ELISA kit SpeciesHuman SpeciesHuman • Human Signal induced proliferation associated protein 1 • Human SLIT ROBO Rho GTPase activating protein 3 • Human Smoothelin like protein 2 SMTNL2 ELISA kit SIPA1 ELISA kit SpeciesHuman SRGAP3 ELISA kit SpeciesHuman SpeciesHuman • Human Signaling lymphocytic activation molecule SLAMF1 • Human Smad nuclear interacting protein 1 SNIP1 ELISA kit • Human Smoothened homolog SMO ELISA kit ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Signaling threshold regulating transmembrane • Human Small acidic protein C11orf58 ELISA kit • Human Sn1 specific diacylglycerol lipase alpha DAGLA adapter 1 SIT1 ELISA kit SpeciesHuman SpeciesHuman ELISA kit SpeciesHuman • Human Signal regulatory protein beta 1 SIRPB1 ELISA kit • Human Small conductance calcium activated potassium • Human Sn1 specific diacylglycerol lipase beta DAGLB SpeciesHuman channel protein 1 KCNN1 ELISA kit SpeciesHuman ELISA kit SpeciesHuman • Human Signal regulatory protein beta 2 SIRPB2 ELISA kit • Human Small conductance calcium activated potassium • Human SNARE associated protein Snapin SNAPIN ELISA SpeciesHuman channel protein 3 KCNN3 ELISA kit SpeciesHuman kit SpeciesHuman • Human Signal regulatory protein delta SIRPD ELISA kit • Human Small EDRK rich factor 1 SERF1A ELISA kit • Human SNF related serine threonine protein kinase SNRK SpeciesHuman SpeciesHuman ELISA kit SpeciesHuman • Human Signal regulatory protein gamma SIRPG ELISA kit • Human Small EDRK rich factor 2 SERF2 ELISA kit • Human snRNA activating protein complex subunit 1 SpeciesHuman SpeciesHuman SNAPC1 ELISA kit SpeciesHuman • Human Signal transducing adaptor protein 1 STAP1 ELISA • Human Small G protein signaling modulator 1 SGSM1 • Human snRNA activating protein complex subunit 2 kit SpeciesHuman ELISA kit SpeciesHuman SNAPC2 ELISA kit SpeciesHuman • Human Signal transducing adaptor protein 2 STAP2 ELISA • Human Small G protein signaling modulator 2 SGSM2 • Human snRNA activating protein complex subunit 3 kit SpeciesHuman ELISA kit SpeciesHuman SNAPC3 ELISA kit SpeciesHuman • Human Sin3 histone deacetylase corepressor complex • Human Small G protein signaling modulator 3 SGSM3 • Human snRNA activating protein complex subunit 4 component SDS3 SUDS3 ELISA kit SpeciesHuman ELISA kit SpeciesHuman SNAPC4 ELISA kit SpeciesHuman • Human Sine oculis binding protein homolog SOBP ELISA • Human Small glutamine rich tetratricopeptide repeat • Human snRNA activating protein complex subunit 5 kit SpeciesHuman containing protein alpha SGTA ELISA kit SpeciesHuman SNAPC5 ELISA kit SpeciesHuman • Human Single Ig IL 1 related receptor SIGIRR ELISA kit • Human Small glutamine rich tetratricopeptide repeat • Human SNRPN upstream reading frame protein SNURF SpeciesHuman containing protein beta SGTB ELISA kit SpeciesHuman ELISA kit SpeciesHuman • Human Single minded homolog 1 SIM1 ELISA kit • Human Small muscular protein SMPX ELISA kit • Human Snurportin 1 SNUPN ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human SNW domain containing protein 1 SNW1 ELISA kit • Human Single minded homolog 2 SIM2 ELISA kit • Human Small nuclear protein PRAC PRAC ELISA kit SpeciesHuman SpeciesHuman SpeciesHuman • Human Sodium and chloride dependent betaine transporter • Human Single strand selective monofunctional uracil DNA • Human Small nuclear ribonucleoprotein E SNRPE ELISA SLC6A12 ELISA kit SpeciesHuman glycosylase SMUG1 ELISA kit SpeciesHuman kit SpeciesHuman • Human Sodium and chloride dependent creatine • Human Single stranded DNA binding protein 2 SSBP2 • Human Small nuclear ribonucleoprotein F SNRPF ELISA transporter 1 SLC6A8 ELISA kit SpeciesHuman ELISA kit SpeciesHuman kit SpeciesHuman • Human Sodium and chloride dependent GABA transporter • Human Single stranded DNA binding protein 3 SSBP3 • Human Small nuclear ribonucleoprotein G SNRPG ELISA 1 SLC6A1 ELISA kit SpeciesHuman ELISA kit SpeciesHuman kit SpeciesHuman • Human Sodium and chloride dependent GABA transporter • Human Single stranded DNA binding protein 4 SSBP4 • Human Small nuclear ribonucleoprotein Sm D1 SNRPD1 2 SLC6A13 ELISA kit SpeciesHuman ELISA kit SpeciesHuman ELISA kit SpeciesHuman • Human Sodium and chloride dependent GABA transporter • Human Single stranded DNA binding protein mitochondrial • Human Small nuclear ribonucleoprotein Sm D2 SNRPD2 3 SLC6A11 ELISA kit SpeciesHuman SSBP1 ELISA kit SpeciesHuman ELISA kit SpeciesHuman • Human Sodium and chloride dependent glycine transporter • Human Sister chromatid cohesion protein DCC1 DSCC1 • Human Small nuclear ribonucleoprotein Sm
Load more

Recommended publications
  • Propranolol-Mediated Attenuation of MMP-9 Excretion in Infants with Hemangiomas
    Supplementary Online Content Thaivalappil S, Bauman N, Saieg A, Movius E, Brown KJ, Preciado D. Propranolol-mediated attenuation of MMP-9 excretion in infants with hemangiomas. JAMA Otolaryngol Head Neck Surg. doi:10.1001/jamaoto.2013.4773 eTable. List of All of the Proteins Identified by Proteomics This supplementary material has been provided by the authors to give readers additional information about their work. © 2013 American Medical Association. All rights reserved. Downloaded From: https://jamanetwork.com/ on 10/01/2021 eTable. List of All of the Proteins Identified by Proteomics Protein Name Prop 12 mo/4 Pred 12 mo/4 Δ Prop to Pred mo mo Myeloperoxidase OS=Homo sapiens GN=MPO 26.00 143.00 ‐117.00 Lactotransferrin OS=Homo sapiens GN=LTF 114.00 205.50 ‐91.50 Matrix metalloproteinase‐9 OS=Homo sapiens GN=MMP9 5.00 36.00 ‐31.00 Neutrophil elastase OS=Homo sapiens GN=ELANE 24.00 48.00 ‐24.00 Bleomycin hydrolase OS=Homo sapiens GN=BLMH 3.00 25.00 ‐22.00 CAP7_HUMAN Azurocidin OS=Homo sapiens GN=AZU1 PE=1 SV=3 4.00 26.00 ‐22.00 S10A8_HUMAN Protein S100‐A8 OS=Homo sapiens GN=S100A8 PE=1 14.67 30.50 ‐15.83 SV=1 IL1F9_HUMAN Interleukin‐1 family member 9 OS=Homo sapiens 1.00 15.00 ‐14.00 GN=IL1F9 PE=1 SV=1 MUC5B_HUMAN Mucin‐5B OS=Homo sapiens GN=MUC5B PE=1 SV=3 2.00 14.00 ‐12.00 MUC4_HUMAN Mucin‐4 OS=Homo sapiens GN=MUC4 PE=1 SV=3 1.00 12.00 ‐11.00 HRG_HUMAN Histidine‐rich glycoprotein OS=Homo sapiens GN=HRG 1.00 12.00 ‐11.00 PE=1 SV=1 TKT_HUMAN Transketolase OS=Homo sapiens GN=TKT PE=1 SV=3 17.00 28.00 ‐11.00 CATG_HUMAN Cathepsin G OS=Homo
    [Show full text]
  • Evolution, Expression and Meiotic Behavior of Genes Involved in Chromosome Segregation of Monotremes
    G C A T T A C G G C A T genes Article Evolution, Expression and Meiotic Behavior of Genes Involved in Chromosome Segregation of Monotremes Filip Pajpach , Linda Shearwin-Whyatt and Frank Grützner * School of Biological Sciences, The University of Adelaide, Adelaide, SA 5005, Australia; fi[email protected] (F.P.); [email protected] (L.S.-W.) * Correspondence: [email protected] Abstract: Chromosome segregation at mitosis and meiosis is a highly dynamic and tightly regulated process that involves a large number of components. Due to the fundamental nature of chromosome segregation, many genes involved in this process are evolutionarily highly conserved, but duplica- tions and functional diversification has occurred in various lineages. In order to better understand the evolution of genes involved in chromosome segregation in mammals, we analyzed some of the key components in the basal mammalian lineage of egg-laying mammals. The chromosome passenger complex is a multiprotein complex central to chromosome segregation during both mitosis and meio- sis. It consists of survivin, borealin, inner centromere protein, and Aurora kinase B or C. We confirm the absence of Aurora kinase C in marsupials and show its absence in both platypus and echidna, which supports the current model of the evolution of Aurora kinases. High expression of AURKBC, an ancestor of AURKB and AURKC present in monotremes, suggests that this gene is performing all necessary meiotic functions in monotremes. Other genes of the chromosome passenger complex complex are present and conserved in monotremes, suggesting that their function has been preserved Citation: Pajpach, F.; in mammals.
    [Show full text]
  • Supplementary Table 1: Adhesion Genes Data Set
    Supplementary Table 1: Adhesion genes data set PROBE Entrez Gene ID Celera Gene ID Gene_Symbol Gene_Name 160832 1 hCG201364.3 A1BG alpha-1-B glycoprotein 223658 1 hCG201364.3 A1BG alpha-1-B glycoprotein 212988 102 hCG40040.3 ADAM10 ADAM metallopeptidase domain 10 133411 4185 hCG28232.2 ADAM11 ADAM metallopeptidase domain 11 110695 8038 hCG40937.4 ADAM12 ADAM metallopeptidase domain 12 (meltrin alpha) 195222 8038 hCG40937.4 ADAM12 ADAM metallopeptidase domain 12 (meltrin alpha) 165344 8751 hCG20021.3 ADAM15 ADAM metallopeptidase domain 15 (metargidin) 189065 6868 null ADAM17 ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) 108119 8728 hCG15398.4 ADAM19 ADAM metallopeptidase domain 19 (meltrin beta) 117763 8748 hCG20675.3 ADAM20 ADAM metallopeptidase domain 20 126448 8747 hCG1785634.2 ADAM21 ADAM metallopeptidase domain 21 208981 8747 hCG1785634.2|hCG2042897 ADAM21 ADAM metallopeptidase domain 21 180903 53616 hCG17212.4 ADAM22 ADAM metallopeptidase domain 22 177272 8745 hCG1811623.1 ADAM23 ADAM metallopeptidase domain 23 102384 10863 hCG1818505.1 ADAM28 ADAM metallopeptidase domain 28 119968 11086 hCG1786734.2 ADAM29 ADAM metallopeptidase domain 29 205542 11085 hCG1997196.1 ADAM30 ADAM metallopeptidase domain 30 148417 80332 hCG39255.4 ADAM33 ADAM metallopeptidase domain 33 140492 8756 hCG1789002.2 ADAM7 ADAM metallopeptidase domain 7 122603 101 hCG1816947.1 ADAM8 ADAM metallopeptidase domain 8 183965 8754 hCG1996391 ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma) 129974 27299 hCG15447.3 ADAMDEC1 ADAM-like,
    [Show full text]
  • Supplementary Table S4. FGA Co-Expressed Gene List in LUAD
    Supplementary Table S4. FGA co-expressed gene list in LUAD tumors Symbol R Locus Description FGG 0.919 4q28 fibrinogen gamma chain FGL1 0.635 8p22 fibrinogen-like 1 SLC7A2 0.536 8p22 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 DUSP4 0.521 8p12-p11 dual specificity phosphatase 4 HAL 0.51 12q22-q24.1histidine ammonia-lyase PDE4D 0.499 5q12 phosphodiesterase 4D, cAMP-specific FURIN 0.497 15q26.1 furin (paired basic amino acid cleaving enzyme) CPS1 0.49 2q35 carbamoyl-phosphate synthase 1, mitochondrial TESC 0.478 12q24.22 tescalcin INHA 0.465 2q35 inhibin, alpha S100P 0.461 4p16 S100 calcium binding protein P VPS37A 0.447 8p22 vacuolar protein sorting 37 homolog A (S. cerevisiae) SLC16A14 0.447 2q36.3 solute carrier family 16, member 14 PPARGC1A 0.443 4p15.1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha SIK1 0.435 21q22.3 salt-inducible kinase 1 IRS2 0.434 13q34 insulin receptor substrate 2 RND1 0.433 12q12 Rho family GTPase 1 HGD 0.433 3q13.33 homogentisate 1,2-dioxygenase PTP4A1 0.432 6q12 protein tyrosine phosphatase type IVA, member 1 C8orf4 0.428 8p11.2 chromosome 8 open reading frame 4 DDC 0.427 7p12.2 dopa decarboxylase (aromatic L-amino acid decarboxylase) TACC2 0.427 10q26 transforming, acidic coiled-coil containing protein 2 MUC13 0.422 3q21.2 mucin 13, cell surface associated C5 0.412 9q33-q34 complement component 5 NR4A2 0.412 2q22-q23 nuclear receptor subfamily 4, group A, member 2 EYS 0.411 6q12 eyes shut homolog (Drosophila) GPX2 0.406 14q24.1 glutathione peroxidase
    [Show full text]
  • (SLC3A2) Sustains Amino Acid and Nucleotide Availability for Cell Cycle
    www.nature.com/scientificreports OPEN CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression Received: 16 April 2019 Sara Cano-Crespo1, Josep Chillarón2, Alexandra Junza3,4, Gonzalo Fernández-Miranda1, Accepted: 13 September 2019 Judit García5,6, Christine Polte7, Laura R. de la Ballina 8,9, Zoya Ignatova7, Óscar Yanes 3,4, Published: xx xx xxxx Antonio Zorzano 1,4,10, Camille Stephan-Otto Attolini 1 & Manuel Palacín1,6,10 CD98 heavy chain (CD98hc) forms heteromeric amino acid (AA) transporters by interacting with diferent light chains. Cancer cells overexpress CD98hc-transporters in order to meet their increased nutritional and antioxidant demands, since they provide branched-chain AA (BCAA) and aromatic AA (AAA) availability while protecting cells from oxidative stress. Here we show that BCAA and AAA shortage phenocopies the inhibition of mTORC1 signalling, protein synthesis and cell proliferation caused by CD98hc ablation. Furthermore, our data indicate that CD98hc sustains glucose uptake and glycolysis, and, as a consequence, the pentose phosphate pathway (PPP). Thus, loss of CD98hc triggers a dramatic reduction in the nucleotide pool, which leads to replicative stress in these cells, as evidenced by the enhanced DNA Damage Response (DDR), S-phase delay and diminished rate of mitosis, all recovered by nucleoside supplementation. In addition, proper BCAA and AAA availability sustains the expression of the enzyme ribonucleotide reductase. In this regard, BCAA and AAA shortage results in decreased content of deoxynucleotides that triggers replicative stress, also recovered by nucleoside supplementation. On the basis of our fndings, we conclude that CD98hc plays a central role in AA and glucose cellular nutrition, redox homeostasis and nucleotide availability, all key for cell proliferation.
    [Show full text]
  • Abnormal Spermatogenesis and Reduced Fertility in Transition Nuclear Protein 1-Deficient Mice
    Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice Y. Eugene Yu*†,Yun Zhang*, Emmanual Unni*‡, Cynthia R. Shirley*, Jian M. Deng§, Lonnie D. Russell¶, Michael M. Weil*, Richard R. Behringer§, and Marvin L. Meistrich*ʈ Departments of *Experimental Radiation Oncology, and §Molecular Genetics, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030-4095; and ¶Department of Physiology, Southern Illinois University, School of Medicine, Carbondale, IL 62901 Edited by Richard D. Palmiter, University of Washington School of Medicine, Seattle, WA, and approved February 22, 2000 (received for review May 3, 1999) Transition nuclear proteins (TPs), the major proteins found in (15), suggesting some functional relationship between the three chromatin of condensing spermatids, are believed to be important proteins exists. Tnp1, however, is on a separate chromosome and for histone displacement and chromatin condensation during is not clearly related to the other three proteins. mammalian spermatogenesis. We generated mice lacking the ma- In vitro, TP1 decreases the melting temperature of DNA (16) jor TP, TP1, by targeted deletion of the Tnp1 gene in mouse and relaxes the DNA in nucleosomal core particles (17), which embryonic stem cells. Surprisingly, testis weights and sperm pro- led to the proposal that TP1 reduces the interaction of DNA duction were normal in the mutant mice, and only subtle abnor- with the nucleosome core. In contrast, TP2 increases the malities were observed in sperm morphology. Electron microscopy melting temperature of DNA and compacts the DNA in revealed large rod-like structures in the chromatin of mutant step nucleosomal cores, suggesting that it is a DNA-condensing 13 spermatids, in contrast to the fine chromatin fibrils observed in protein (18).
    [Show full text]
  • Supplementary Table 1
    Supplementary Table 1. Phosphoryl I-Area II-Area II-Debunker III-Area Gene Symbol Protein Name Phosphorylated Peptide I-R2 I-Debunker score II-R2 III-R2 ation Site Ratio Ratio score Ratio 92154 ABBA-1 Actin-bundling protein with BAIAP2 homologyK.TPTVPDS*PGYMGPTR.A S601 1.76 0.95 0.999958250 1.18 0.98 0.999971836 0.98 0.98 92154 ABBA-1 Actin-bundling protein with BAIAP2 homologyR.AGS*EECVFYTDETASPLAPDLAK.A S612 1.40 0.99 0.999977464 1.03 0.99 0.999986373 1.00 0.99 92154 ABBA-1 Actin-bundling protein with BAIAP2 homologyK.GGGAPWPGGAQTYS*PSSTCR.Y S300 0.49 0.98 0.999985406 0.97 0.99 0.999983906 2.03 0.97 23 ABCF1 ATP-binding cassette sub-family F memberK.QQPPEPEWIGDGESTS*PSDK.V 1 S22 1.09 0.98 0.872361494 0.81 1.00 0.847115585 0.97 0.97 27 ABL2 Isoform IA of Tyrosine-protein kinase ABL2K.VPVLIS*PTLK.H S936 0.76 0.98 0.999991559 1.06 0.99 0.999989547 0.99 0.96 3983 ABLIM1 Actin binding LIM protein 1 R.TLS*PTPSAEGYQDVR.D S433 1.27 0.99 0.999994010 1.16 0.98 0.999989861 1.11 0.99 31 ACACA acetyl-Coenzyme A carboxylase alpha isoformR.FIIGSVSEDNS*EDEISNLVK.L 1 S29 1.23 0.99 0.999992898 0.72 0.99 0.999992499 0.83 0.99 65057 ACD Adrenocortical dysplasia protein homologR.TPS*SPLQSCTPSLSPR.S S424 1.51 0.90 0.999936226 0.82 0.88 0.997623142 0.46 0.93 22985 ACIN1 Apoptotic chromatin condensation inducerK.ASLVALPEQTASEEET*PPPLLTK.E in the nucleus T414 0.90 0.92 0.922696554 0.91 0.92 0.993049132 0.95 0.99 22985 ACIN1 Apoptotic chromatin condensation inducerK.ASLVALPEQTAS*EEETPPPLLTK.E in the nucleus S410 1.02 0.99 0.997470008 0.80 0.99 0.999702808 0.96
    [Show full text]
  • Lecture9'21 Chromatin II
    Genetic Organization -Chromosomal Arrangement: From Form to Function. Chapters 9 & 10 in Genes XI The Eukaryotic chromosome – Organized Structures -banding – Centromeres – Telomeres – Nucleosomes – Euchromatin / Heterochromatin – Higher Orders of Chromosomal Structure 2 Heterochromatin differs from euchromatin in that heterochromatin is effectively inert; remains condensed during interphase; is transcriptionally repressed; replicates late in S phase and may be localized to the centromere or nuclear periphery Facultative heterochromatin is not restricted by pre-designated sequence; genes that are moved within or near heterochromatic regions can become inactivated as a result of their new location. Heterochromatin differs from euchromatin in that heterochromatin is effectively inert; remains condensed during interphase; is transcriptionally repressed; replicates late in S phase and may be localized to the centromere or nuclear periphery Facultative heterochromatin is not restricted by pre-designated sequence; genes that are moved within or near heterochromatic regions can become inactivated as a result of their new location. Chromatin inactivation (or heterochromatin formation) occurs by the addition of proteins to the nucleosomal fiber. May be due to: Chromatin condensation -making it inaccessible to transcriptional apparatus Proteins that accumulate and inhibit accessibility to the regulatory sequences Proteins that directly inhibit transcription Chromatin Is Fundamentally Divided into Euchromatin and Heterochromatin • Individual chromosomes can be seen only during mitosis. • During interphase, the general mass of chromatin is in the form of euchromatin, which is slightly less tightly packed than mitotic chromosomes. TF20210119 Regions of compact heterochromatin are clustered near the nucleolus and nuclear membrane Photo courtesy of Edmund Puvion, Centre National de la Recherche Scientifique Chromatin: Basic Structures • nucleosome – The basic structural subunit of chromatin, consisting of ~200 bp of DNA wrapped around an octamer of histone proteins.
    [Show full text]
  • THE DEVELOPMENT of CHEMICAL METHODS to DISCOVER KINASE SUBSTRATES and MAP CELL SIGNALING with GAMMA-MODIFIED ATP ANALOG-DEPENDENT KINASE-CATALYZED PHOSPHORYLATION By
    Wayne State University Wayne State University Dissertations 1-1-2017 The evelopmeD nt Of Chemical Methods To Discover Kinase Substrates And Map Cell Signaling With Gamma-Modified Atp Analog- Dependent Kinase-Catalyzed Phosphorylation Dissanayaka Mudiyanselage Maheeka Madhubashini Embogama Wayne State University, Follow this and additional works at: https://digitalcommons.wayne.edu/oa_dissertations Part of the Analytical Chemistry Commons, and the Biochemistry Commons Recommended Citation Embogama, Dissanayaka Mudiyanselage Maheeka Madhubashini, "The eD velopment Of Chemical Methods To Discover Kinase Substrates And Map Cell Signaling With Gamma-Modified Atp Analog-Dependent Kinase-Catalyzed Phosphorylation" (2017). Wayne State University Dissertations. 1698. https://digitalcommons.wayne.edu/oa_dissertations/1698 This Open Access Dissertation is brought to you for free and open access by DigitalCommons@WayneState. It has been accepted for inclusion in Wayne State University Dissertations by an authorized administrator of DigitalCommons@WayneState. THE DEVELOPMENT OF CHEMICAL METHODS TO DISCOVER KINASE SUBSTRATES AND MAP CELL SIGNALING WITH GAMMA-MODIFIED ATP ANALOG-DEPENDENT KINASE-CATALYZED PHOSPHORYLATION by DISSANAYAKA M. MAHEEKA M. EMBOGAMA DISSERTATION Submitted to the Graduate School of Wayne State University, Detroit, Michigan in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY 2017 MAJOR: CHEMISTRY (Biochemistry) Approved By: Advisor Date DEDICATION To my beloved mother, father, husband, daughter and sister. ii ACKNOWLEGEMENTS Many people have helped me during the past five years of earning my PhD. I would like to take this opportunity to convey my gratitude to them. First and foremost, I would like to thank my research supervisor Dr. Mary Kay Pflum for being the greatest mentor that I have met so far.
    [Show full text]
  • The VE-Cadherin/Amotl2 Mechanosensory Pathway Suppresses Aortic InAmmation and the Formation of Abdominal Aortic Aneurysms
    The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inammation and the formation of abdominal aortic aneurysms Yuanyuan Zhang Karolinska Institute Evelyn Hutterer Karolinska Institute Sara Hultin Karolinska Institute Otto Bergman Karolinska Institute Maria Forteza Karolinska Institute Zorana Andonovic Karolinska Institute Daniel Ketelhuth Karolinska University Hospital, Stockholm, Sweden Joy Roy Karolinska Institute Per Eriksson Karolinska Institute Lars Holmgren ( [email protected] ) Karolinska Institute Article Keywords: arterial endothelial cells (ECs), vascular disease, abdominal aortic aneurysms Posted Date: June 15th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-600069/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms Yuanyuan Zhang1, Evelyn Hutterer1, Sara Hultin1, Otto Bergman2, Maria J. Forteza2, Zorana Andonovic1, Daniel F.J. Ketelhuth2,3, Joy Roy4, Per Eriksson2 and Lars Holmgren1*. 1Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden. 2Department of Medicine Solna, BioClinicum, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. 3Department of Cardiovascular and Renal Research, Institutet of Molecular Medicine, Univ. of Southern Denmark, Odense, Denmark 4Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm,
    [Show full text]
  • Supp Table 6.Pdf
    Supplementary Table 6. Processes associated to the 2037 SCL candidate target genes ID Symbol Entrez Gene Name Process NM_178114 AMIGO2 adhesion molecule with Ig-like domain 2 adhesion NM_033474 ARVCF armadillo repeat gene deletes in velocardiofacial syndrome adhesion NM_027060 BTBD9 BTB (POZ) domain containing 9 adhesion NM_001039149 CD226 CD226 molecule adhesion NM_010581 CD47 CD47 molecule adhesion NM_023370 CDH23 cadherin-like 23 adhesion NM_207298 CERCAM cerebral endothelial cell adhesion molecule adhesion NM_021719 CLDN15 claudin 15 adhesion NM_009902 CLDN3 claudin 3 adhesion NM_008779 CNTN3 contactin 3 (plasmacytoma associated) adhesion NM_015734 COL5A1 collagen, type V, alpha 1 adhesion NM_007803 CTTN cortactin adhesion NM_009142 CX3CL1 chemokine (C-X3-C motif) ligand 1 adhesion NM_031174 DSCAM Down syndrome cell adhesion molecule adhesion NM_145158 EMILIN2 elastin microfibril interfacer 2 adhesion NM_001081286 FAT1 FAT tumor suppressor homolog 1 (Drosophila) adhesion NM_001080814 FAT3 FAT tumor suppressor homolog 3 (Drosophila) adhesion NM_153795 FERMT3 fermitin family homolog 3 (Drosophila) adhesion NM_010494 ICAM2 intercellular adhesion molecule 2 adhesion NM_023892 ICAM4 (includes EG:3386) intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)adhesion NM_001001979 MEGF10 multiple EGF-like-domains 10 adhesion NM_172522 MEGF11 multiple EGF-like-domains 11 adhesion NM_010739 MUC13 mucin 13, cell surface associated adhesion NM_013610 NINJ1 ninjurin 1 adhesion NM_016718 NINJ2 ninjurin 2 adhesion NM_172932 NLGN3 neuroligin
    [Show full text]
  • Transporters
    Alexander, S. P. H., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A., & CGTP Collaborators (2019). The Concise Guide to Pharmacology 2019/20: Transporters. British Journal of Pharmacology, 176(S1), S397-S493. https://doi.org/10.1111/bph.14753 Publisher's PDF, also known as Version of record License (if available): CC BY Link to published version (if available): 10.1111/bph.14753 Link to publication record in Explore Bristol Research PDF-document This is the final published version of the article (version of record). It first appeared online via Wiley at https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14753. Please refer to any applicable terms of use of the publisher. University of Bristol - Explore Bristol Research General rights This document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/red/research-policy/pure/user-guides/ebr-terms/ S.P.H. Alexander et al. The Concise Guide to PHARMACOLOGY 2019/20: Transporters. British Journal of Pharmacology (2019) 176, S397–S493 THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters Stephen PH Alexander1 , Eamonn Kelly2, Alistair Mathie3 ,JohnAPeters4 , Emma L Veale3 , Jane F Armstrong5 , Elena Faccenda5 ,SimonDHarding5 ,AdamJPawson5 , Joanna L Sharman5 , Christopher Southan5 , Jamie A Davies5 and CGTP Collaborators 1School of Life Sciences,
    [Show full text]