Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_900188005Cyc: Actinoplanes regularis DSM 43151 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari a reduced CycA1 H + H + cytochrome UQH UQH UQH UQH MQH UQH UQ an amino an amino an amino an amino D-mannose 2 2 2 2 an oxidized 2 an oxidized 2 an oxidized a C4- + phosphate acid acid acid acid aldehydo-D-mannose a branched- K a branched- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- a 2,3,4- c-type c-type CycA1 dicarboxylate phosphate phosphate β K + putrescine α α a C4- an aliphatic an aliphatic α sn-glycerol formate an amino an amino an amino an amino an amino Ni 2+ an amino an amino an amino an amino -D-mannopyranose cytochrome cytochrome cytochrome chain 2+ 2+ 2+ 2+ 2+ chain 2+ 2+ N-acetyl- -D- N-acetyl- -D- phosphate phosphate N-acetyl- -D- 2+ saturated saturated saturated saturated saturated saturated saturated saturated saturated saturated saturated saturated a carbohydrate a carbohydrate a sulfonate (S)-lactate a carbohydrate a carbohydrate a carbohydrate + a carbohydrate a carbohydrate a carbohydrate a carbohydrate Zn Zn Zn Ca D-galactose a sugar a carbohydrate Mo an antibiotic Cd Co a nucleotide a macrolide a macrolide a nucleotide a carbohydrate 3-phosphate Cu an antibiotic molybdate chromate a dipeptide a dipeptide acid acid acid acid acid a carbohydrate acid acid acid acid α-D-mannopyranose amino acid K spermidine amino acid glucosamine glucosamine dicarboxylate sulfonate sulfonate glucosamine an oligopeptide fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid fatty acid predicted predicted predicted predicted predicted ABC predicted predicted ABC ABC ABC ABC transporter ATP-driven ABC RS00190 RS30780 CydB CydB RS09765 RS32935 CydB RS20230 CydB RS39140 RS06635 RS08400 RS08400 RS08400 RS35925 RS08495 KdpB RS18030 RS00685 RS18105 RS18230 RS25800 RS38545 RS25835 RS16300 RS29365 RS30775 RS30885 RS06215 ModB RS33030 RS08500 RS34625 CbiQ GrpE NgcE NgcE RS01555 RS20615 RS32225 RS03955 RS18145 RS33180 RS17825 RS35390 PstS NgcE GrpE RS19265 RS35165 FocA RS36335 RS18395 ModA RS16565 RS21815 RS11155 RS39060 RS20800 RS04025 RS38950 RS40460 RS32770 RS01155 RS02110 RS15875 RS07685 RS17455 transporter transporter transporter transporter RS17080 RS12850 RS06740 RS43690 RS04240 RS23930 RS07700 RS38020 RS05935 RS18570 RS17275 RS17365 of a C4- transporter transporter of an of an of an of an dicarboxylate of K+ of phosphate amino acid amino acid amino acid amino acid α α α D-mannose 6-phosphate a branched- K + a sugar 6- putrescine a branched- N-acetyl- -D- N-acetyl- -D- a C4- an aliphatic an aliphatic phosphate phosphate N-acetyl- -D- formate Ni 2+ a carbohydrate O O a carbohydrate a sulfonate O (S)-lactate O a carbohydrate a carbohydrate MQ UQ a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate Zn 2+ Zn 2+ Zn 2+ Ca 2+ D-galactose a carbohydrate Mo 2+ an antibiotic Cd 2+ Co 2+ a nucleotide a macrolide a macrolide a nucleotide a carbohydrate sn-glycerol Cu 2+ an antibiotic molybdate chromate a dipeptide a dipeptide an amino an amino an amino an amino an amino a carbohydrate an amino an amino an amino an amino H + AtpC H + aldehydo-D-mannose 6-phosphate 2 2 2 2 chain + phosphate chain glucosamine glucosamine phosphate phosphate glucosamine diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate diphosphate K spermidine dicarboxylate sulfonate sulfonate 3-phosphate acid acid acid acid acid an oligopeptide acid acid acid acid β-D-mannopyranose 6-phosphate UQ H O UQ H O UQ H O UQ H O UQH amino acid a C4- + amino acid 2 2 2 2 2 K phosphate α-D-mannopyranose 6-phosphate dicarboxylate an amino an amino an amino an amino acid acid acid acid

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Amino Acid Degradation C1 Compound Utilization and Assimilation glyoxylate cycle a (1->4)-β-D-xylan 6,7-dimethyl-8-(1- a β-D-glucan with a 7,8- a 1-acyl-sn-glycero- a β-D-glucosyl-N D-glucopyranose N-ethylglycine lichenan a cellodextrin L-canavanine acetylxylan canavaninosuccinate a phthalylamide maltotetraose D-glucopyranose maltohexaose maltose cob(II)yrinate a,c-diamide molybdenum cofactor biosynthesis Amine and Polyamine Biosynthesis L-valine degradation I L-histidine degradation I formaldehyde oxidation formaldehyde oligosaccharide D-ribityl)lumazine C3-substituted glucose dihydromonapterin 3-phosphocholine -acylsphingosine maltose RS30950 maltose [2Fe-2S] iron-sulfur cluster biosynthesis superpathway of tetrahydrofolate biosynthesis mycothiol biosynthesis succinate acetyl-CoA L-leucine degradation I glycine riboflavin synthase acetylxylan esterase: endo-1,3(4)- glucosylceramidase: 4-alpha- 4-alpha- biosynthesis II (late VII (THF pathway) oxidation II xylose arginase: argininosuccinate phthalyl amidase: dihydroneopterin lysophospholipase: L-tryptophan oxidase licheninase: cellobiohydrolase: beta-xylosidase: subunit alpha: CHC09_RS18495 beta-glucanase: CHC09_RS12200 glucanotransferase: malQ glucanotransferase: malQ cobalt incorporation) D-glucopyranose spermine biosynthesis (glutathione-dependent) isomerase: CHC09_RS03050 lyase: argH CHC09_RS18430 aldolase: folB CHC09_RS30460 spermidine biosynthesis I val degradation I formaldehyde CHC09_RS21085 CHC09_RS05665 CHC09_RS06125 CHC09_RS15195 a sphingosine cys putrescine his xylA ThiO: thiO CHC09_RS31150 acetate xylan fumarate a substituted amine phthalate 6-(hydroxymethyl) glycolaldehyde sn-glycero-3- a carboxylate D-glucopyranose maltose maltotriose D-glucopyranose maltoheptaose uroporphyrinogen-III L-cysteine desulfurase 6-phosphate glyoxylate malate leu (via anthranilate) formaldehyde urea L-canaline L-canavanine ceramide GTP ATP biosynthesis I isocitrate lyase: histidine ethylamine glyoxylate riboflavin ARP a β-D glucan a β-D glucan -7,8-dihydropterin phosphocholine leu RS01855 leu uroporphyrinogen-III inositol-3- synthase branched-chain branched-chain L-isoleucine degradation I keto-D-fructose a short glucan β-D-cellobiose β-D-xylopyranose cysteine SAM CHC09_RS13210 ammonia- trp C-methyltransferase: cysteine phosphate SAM A: aceB amino acid amino acid a 5,10- a 2,3,4- GTP cyclohydrolase desulfurase: GTP arg isocitrate lyase/ lyase: hutH cobA desulfurase: synthase: S-adenosylmethionine aminotransferase: aminotransferase: tryptophan 2,3- methylenetetrahydrofolate S-(hydroxymethyl) diphosphate RS39690 saturated I FolE: CHC09_RS07250 S-adenosylmethionine phosphoenolpyruvate malate urocanate a 1-(1-alkenyl) CHC09_RS07250 CHC09_RS14460 pyruvoyl- decarboxylase: CHC09_RS02825 CHC09_RS02825 ile dioxygenase: glutathione uridine (2R,3S)-2- UTP 3-oxo-(11Z)- 1-18:1-2- fatty acid bifunctional CHC09_RS09895 decarboxylase: synthase 4-methyl-2- bifunctional 5,10- cellulose a xyloglucan a chitodextrin an aliphatic amine (S)-citramalate (3S)-citryl-CoA decanoyl-CoA acetyl-CoA a ribonucleic acid a maltodextrin D-glucopyranose a xyloglucan cysteine cysteine GTP 3',8- dependent arginine CHC09_RS24245 mutase family protein: branched-chain urocanate kynA methylisocitrate octadecenoyl-CoA lysophosphatidylethanolamine -sn-glycero-3- uroporphyrinogen-III inositol-3- a carboxy- CHC09_RS24245 A: aceB 3-methyl-2- oxopentanoate N-formylkynurenine methylenetetrahydrofolate glutathione- uridine kinase: nucleoside triphosphate 4-alpha- xyloglucanase: desulfurase: GTP desulfurase: cyclase MoaA: decarboxylase: putrescine dAdoMet CHC09_RS06620 amino acid hydratase: endoglucanase: chitinase: primary-amine citramalate methylisocitrate citryl-CoA lyase: acetyl-CoA C- acetyl-CoA C- ribonuclease PH: lysophospholipase: phosphocholine C-methyltransferase/ phosphate adenylated oxobutanoate dehydrogenase/5,10- dependent CHC09_RS12520 xyloglucanase: pyrophosphohydrolase: lysoplasmalogenase: glucanotransferase: malQ CHC09_RS19580 CHC09_RS02960 cyclohydrolase CHC09_RS02960 CHC09_RS22850 dAdoMet CHC09_RS06450 aminotransferase: CHC09_RS24280 CHC09_RS33315 CHC09_RS14155 oxidase: synthase: lyase: CHC09_RS27805 acyltransferase: acyltransferase: CHC09_RS24310 CHC09_RS30460 uroporphyrinogen- synthase: an [L-cysteine [small subunit of spermidine methenyltetrahydrofolate formaldehyde uridine kinase: CHC09_RS19580 CHC09_RS11370 CHC09_RS40265 XLLG xyloglucan XLXG xyloglucan XXLG xyloglucan XXXG xyloglucan I FolE: folE (8S)-3',8-cyclo-7,8- agmatine CHC09_RS02825 [+ 8 isozymes] [+ 4 isozymes] CHC09_RS14010 CHC09_RS02815 CHC09_RS18980 CHC09_RS18545 CHC09_RS18545 a nucleoside sn-glycero-3- sn-glycero-3- maltose a maltodextrin III synthase: CHC09_RS23030 molybdopterin (S)-3-methyl-2- 4-imidazolone- cyclohydrolase: dehydrogenase: CHC09_RS05425 acetyl-CoA oxaloacetate 3-oxododecanoyl- a ribonucleic acid oleate a fatty aldehyde oligosaccharide oligosaccharide oligosaccharide oligosaccharide an S-sulfanyl-[L- 7,8- desulfurase]-S- dihydroguanosine a xyloglucan N,N'- acetate pyruvate succinate UMP diphosphate phosphoethanolamine phosphocholine CHC09_RS05160 D-threo-isocitrate (S)-malate oxopentanoate 5-propanoate CHC09_RS36685 a cellodextrin pyruvate palmitoleoyl-CoA acetyl-CoA cysteine desulfurase] dihydroneopterin superpathway of thiamine diphosphate biosynthesis I sulfanyl-L-cysteine synthase] 5'-triphosphate spermine synthase: agmatinase: isovaleryl-CoA CHC09_RS01560 UMP oligosaccharide diacetylchitobiose an aldehyde CoA precorrin-1 spermidine a 2,3,4- 3'-triphosphate Ins(3)P UDP-N-acetyl- CHC09_RS03820 speB isobutanoyl-CoA imidazolonepropionase: L-kynurenine a 5,10- glutathione- α cyclic pyranopterin diphosphate RS40590 saturated -D-glucosamine CHC09_RS24295 methenyltetrahydrofolate dependent uroporphyrinogen-III monophosphate fatty acid cys putrescine aconitate malate formaldehyde a plant soluble C-methyltransferase: D-inositol-3-phosphate synthase spermine S-methyl-5'-thioadenosine kynureninase: bifunctional 5,10- phosphoenol α (S)-4-hydroxy- 3-oxo-(5Z)- 4-trans-3-oxo- 3-oxo-(7Z)- N-formimino- -maltose cellotetraose a primary amine reduced riboflavin 1-butanesulfonate sec [DNA] D-glucopyranose maltohexaose D-glucopyranose an oligoglycosylglucosylceramide an S-sulfanyl-[cysteine a thiocarboxylated MoaC: moaC hydratase dehydrogenase: 2-methylbutanoyl-CoA dehydrogenase: a tRNA ser asp fumarate heteroglycan cobA 7,8- cysteine glycosyltransferase: 3-methylcrotonyl- kynU methylenetetrahydrofolate pyruvate 2-oxopentanoate dodecenoyl-CoA undecenoyl-CoA tetradecenoyl-CoA desulfurase]-[disordered- [small subunit of cyclic AcnA: acnA CHC09_RS31840 L-glutamate CHC09_RS43410 alkanesulfonate 4-hydroxy-2- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- exodeoxyribonuclease 4-alpha- 4-alpha- endoglycosylceramidase: dihydroneopterin desulfurase: mshA CoA dehydrogenase/5,10- primary-amine flavin reductase: serine--tRNA ligase: L-aspartate oxidase: bifunctional form scaffold molybdopterin pyranopterin methylacrylyl-CoA formiminoglutamate anthranilate pyruvate maltokinase: cellobiohydrolase: monooxygenase: oxovalerate acyltransferase: acyltransferase: acyltransferase: III: xth glucanotransferase: glucanotransferase: malQ CHC09_RS13635 3'-phosphate acetyl/propionyl/ methenyltetrahydrofolate oxidase: CHC09_RS32940 CHC09_RS22785 CHC09_RS21470 uroporphyrinogen-III protein] complex CHC09_RS07250 synthase] phosphate S-formylglutathione kinase: pyk CHC09_RS17685 CHC09_RS05665 CHC09_RS41970 aldolase: dmpG CHC09_RS18545 CHC09_RS18545 CHC09_RS18545 a 2'- malQ 1-O-(2-acetamido- formiminohydrolase: cyclohydrolase: CHC09_RS14010 [+ 10 isozymes] an L-seryl- maltose maltopentaose a ceramide an oligoglycosylglucose C-methyltransferase/ cysteine cysteine enoyl-CoA methylcrotonyl- (3Z)-dec-3- 2-trans- (5Z)- succinate 2-iminosuccinate deoxyribonucleoside [DNA] a plant soluble α NAD phosphorylation speB α-maltose 1- pyruvate sec maltose desulfurase: chorismate 2-deoxy- -D- cis-aconitate oxaloacetate hydratase: CoA carboxylase (E)-2- CHC09_RS01560 β-D-cellobiose sulfite butan-1-al acetaldehyde [tRNA ] acetyl-CoA acetyl-CoA acetyl-CoA 5'-monophosphate heteroglycan a 2,3,4- uroporphyrinogen- desulfurase: molybdopterin pyruvate phosphate an aldehyde riboflavin enoyl-CoA nonenoyl-CoA dodecenoyl-CoA CHC09_RS07250 glucopyranosyl)-1D-myo and dephosphorylation CHC09_RS17360 subunit alpha: methylcrotonoyl-CoA diphosphate RS41805 saturated III synthase: 7,8- aminodeoxychorismate CHC09_RS02960 synthase: Glu a 10- an [L-cysteine -inositol 3-phosphate aconitate CHC09_RS16680 enoyl-CoA fatty acid CHC09_RS05160 cysteine dihydroneopterin synthase, CHC09_RS22895 NAD + enoyl-CoA formyltetrahydrofolate desulfurase]-S- hydratase hydratase: L-cysteine formate desulfurase: component I: pabB hydratase: 3-methylglutaconyl- lipid A 6-trans-3-oxo- a long-linear L-4-hydroxyphenylglycine-L- dihydroneopterin AcnA: acnA CHC09_RS17360 degradation II formyltetrahydrofolate (indol-3-yl) D-glucopyranose a glucan maltotriose α-D-glucopyranose maltopentaose D-glucopyranose precorrin-2 CHC09_RS02960 sulfanyl-L-cysteine CHC09_RS17515 CoA citrate acetamide sarcosine allantoate disaccharide H O diphosphate isethionate (-)-methyl jasmonate an all-trans-retinyl ester α-D-glucan arginyl-D-4-hydroxyphenylglycine- a [cysteine desulfurase]- [+ 2 isozymes] Aminoacyl-tRNA Charging deformylase: purU acetamide 2 tridecenoyl-CoA aldolase: folB cysteine 1-(2-acetamido- molybdopterin citrate synthase: enoyl-CoA 4-alpha- 4-alpha- 4-alpha- 20 (S)-3-hydroxy- aconitate allantoate tetraacyldisaccharide inorganic alkanesulfonate carboxylesterase/ acetyl-CoA C- carboxylesterase/ L-seryl-L 4-hydroxyphenylglycine precorrin-2 (C )- S-sulfanyl-[disordered- 4-amino-4- desulfurase: α alkaline NAD kinase: glycine pyranose oxidase: trypsin: CHC09_RS03600 6-(hydroxymethyl) a ThiS sulfur- 2-deoxy- -D- molybdopterin CHC09_RS12455 isobutanoyl-CoA hydratase: cys formate amidase: amidase: 4'-kinase: pyrophosphatase: monooxygenase: lipase family protein: acyltransferase: glucanotransferase: lipase family protein: glucanotransferase: glucanotransferase: malQ methyltransferase: form scaffold deoxychorismate phosphatase: CHC09_RS36320 acetyl-CoA L-proline degradation hydratase oxidase amidohydrolase: CHC09_RS17135 [+ 2 isozymes] -7,8-dihydropterin CHC09_RS07250 carrier protein glucopyranosyl)- adenylyltransferase: tRNA charging [+ 3 isozymes] CHC09_RS17515 cystathionine CHC09_RS11595 CHC09_RS11595 CHC09_RS12320 CHC09_RS41970 CHC09_RS33810 CHC09_RS18545 malQ CHC09_RS33810 malQ maltose maltotetraose CHC09_RS00505 protein] complex gln AcnA: acnA ThiO: thiO CHC09_RS24285 CHC09_RS21645 D-4-hydroxyphenylglycine-L- a 2,3,4- aminodeoxychorismate cysteine 1D-myo-inositol CHC09_RS30905 ATP-NAD kinase: glutaminyl-tRNA gamma-lyase: 4-trans- L-4-hydroxyphenylglycine-L-arginine cysteine 2-amino-4-hydroxy-6- CHC09_RS22905 arginine-- HMG-CoA (2S,3S)-3-hydroxy-2- 2-dehydro-D- + sulfite glycolaldehyde MeOH (-)-jasmonate acetyl-CoA D-glucopyranose a glucan a fatty acid all-trans-retinol a short glucan a short glucan seryl-L 4-hydroxyphenylglycine lyase: CHC09_RS31315 [+ 5 isozymes] CHC09_RS00280 biosynthesis via citrate methylamine glyoxylate lipid IV phosphate H diphosphate RS37365 saturated (indol-3-yl)acetate A undecenoyl-CoA precorrin-3A desulfurase: hydroxymethyldihydropteridine desulfurase: N-acetyl-1-D-myo- molybdopterin tRNA ligase: methylbutanoyl-CoA pro 2-aminoprop-CHC09_RS02670 D-threo-isocitrate acetate (S)-ureidoglycine glucopyranose aminodeoxychorismate transamidation fatty acid CHC09_RS07250 diphosphokinase: folK CHC09_RS02960 inositol-2-amino- adenine CHC09_RS09175 (S)-3-hydroxy- hydroxymethylglutaryl- proline 2-enoate precorrin-3B lyase: CHC09_RS31320 D-glyceraldehyde (7,8-dihydropterin- a [ThiI sulfur- a carboxy- 2-deoxy-alpha- D- dinucleotide Glu isobutanoate CoA lyase: dehydrogenase: cysteine 3-phosphate + arginine-- synthase: 6-yl)methyl carrier protein]- adenylated- glucopyranoside molybdopterin NADP arg CHC09_RS43185 CHC09_RS05225 3-[(3'-methylthio) D-gluconate 5-cis, 7-trans-3-oxo- 6-cis, 3-oxo- a 1-O-(alk-1-enyl)-sn-glycero- 5,10-methylene- 3-methyl-2- desulfurase: 4-aminobenzoate tRNA ligase: (S)-1-pyrroline- orotidine 5'- D-galactopyranose + a 1,3-β-D-glucan CHC09_RS00495 1-deoxy-D- S-sulfanyl- [ThiS sulfur- Pentose Phosphate Pathways (S)-lactate ferroheme o phenylglyoxylate tRNA Asn asp tryptamine secologanin all-trans-retinyl palmitate a plastoquinone NAD(P)H H CHC09_RS02960 diphosphate deacetylase: mshB superpathway of thiamine diphosphate biosynthesis II molybdenumtransferase hydroxymethylglutaryl- 2-methylacetoacetyl-CoA phosphate propyl]malate 6-phosphate tetradecadienoyl-CoA tridecenoyl-CoA 3-phosphoethanolamine tetrahydromethanopterin oxobutanoate xylulose-5- CHC09_RS03365 an L-arginyl- 5-carboxylate Alcohol Degradation strictosidine acetyl-CoA C- acetyl-CoA C- carboxylesterase/ NAD(P)H-quinone glucan endo-1,3- 3-methyl-2-oxobutanoate an S-sulfanyl-[cysteine tyr L-cysteine carrier protein] MoeA: CHC09_RS04910 an L-glutamyl- CoA lyase: lactate 2- benzoylformate 3-isopropylmalate aspartate-- galactose oxidase: 6-phosphogluconate lysoplasmalogenase: precorrin-3B [tRNA Arg ] (S)-methylmalonate- 2-iminopropanoate orotidine-5'- desulfurase]-S- AIR phosphate GlcN-Ins Gln pentose phosphate pathway acetyl-CoA heme A synthase: CHC09_RS15340 synthase: acyltransferase: acyltransferase: lipase family protein: dehydrogenase: beta-D-glucosidase: CHC09_RS40265 hydroxymethyltransferase: molybdopterin Arg [tRNA ] CHC09_RS19170 phosphate monooxygenase: decarboxylase: dehydrogenase: tRNA(Asn) ligase: dehydrogenase synthase: cys a tRNA semialdehyde CHC09_RS07280 CHC09_RS25510 sn-glycero-3- a 2,3,4- 17 sulfanyl-[disordered- (non-oxidative branch) acetyltransferase: glycerol and glycerophosphodiester degradation CHC09_RS06795 CHC09_RS21170 CHC09_RS02830 CHC09_RS08610 [+ 3 isozymes] (decarboxylating): gnd CHC09_RS25470 CHC09_RS18545 CHC09_RS18545 CHC09_RS33810 CHC09_RS04510 panB precorrin-3B (C )- L-cysteine : 1 D- molybdenumtransferase glutamyl-tRNA decarboxylase: 3-α(S)- (3Z,5E)-dodeca- 4-cis- a fatty aldehyde diphosphate RS05490 saturated form scaffold phosphomethylpyrimidine dxs acetoacetate an L-aspartyl- + D-glucopyranose a 1,3-β-D-glucan phosphoethanolamine methyltransferase: 7,8- MoeA: CHC09_RS22900 D-ribulose CHC09_RS05940 pyrF 6-(methylthio)- D-galacto- D-ribulose acetyl-CoA acetyl-CoA palmitate all-trans-retinol NAD(P) a plastoquinol THMPT 2-dehydropantoate synthase ThiC: myo-inositol 2- cysteine a ThiS sulfur- amidotransferase: 4-aminobutyrate methylmalonate- L-glutamate-5- acetate ferroheme a benzaldehyde [tRNA Asn ] strictosidine 3,5-dienoyl-CoA undecenoyl-CoA fatty acid CHC09_RS00505 protein] complex dihydropteroate 1-deoxy-D- MoO - [+ 7 isozymes] UMP 2-oxohexanoate hexodialdose 5-phosphate cysteine CHC09_RS10850 a thiocarboxy- amino-2-deoxy-α- desulfurase: carrier protein 2 CHC09_RS21755 5-phosphate semialdehyde semialdehyde a glycerophosphodiester glycerol xylulose 5- 2-iminoacetate molybdopterin glutathione aminotransferase, glycine cleavage desulfurase: bifunctional [ThiS-Protein] D-glucopyranoside CHC09_RS07250 pyruvate glycerophosphodiester precorrin-4 phosphate cofactor biosynthesis cysteine-- an L-glutaminyl- mitochondrial: dehydrogenase propanoyl-CoA acetyl-CoA 1-pyrroline-5- glycerol CHC09_RS07250 HMP-P cys ribose 5- ribulose- folylpolyglutamate ligase: cysteine [tRNA Gln ] CHC09_RS36060 (CoA acylating) carboxylate phosphodiesterase: kinase: an O-acetyl- tRNA ligase: a [glycine- cobalt- (2R,3S)-3- 3-[(7'-methylthio) 3-oxo- 4-hydroxybenzoyl- 3-oxo-(6Z,9Z,12Z,15Z,18Z) a sialyloligosaccharide precorrin-4 C(11)- cysteine synthase/ thiazole synthase: CHC09_RS12615 phosphate phosphate 3- : mmsA CHC09_RS22725 propionamide a tRNA Asx an oligopeptide O-acetyl-L-serine thiosulfate ADP-ribose acetyl-CoA methyl (indol-3-yl)acetate (+)-7-epi-jasmonoyl-CoA acetyl-CoA a 1-phosphatidyl-1D-myo-inositol a dihydroceramide bifunctional desulfurase: cys Glu CHC09_RS35140 an L-cysteinyl- dehydrogenase: cleavage complex glpK D-ala precorrin-6A isopropylmalate heptyl]malate asp myristoyl-CoA CoA -tetracosapentaenoyl-CoA methyltransferase: desulfurase: dihydrofolate CHC09_RS10835 a carboxy- isomerase epimerase: 6 S9 family cysteine O-acetyl-ADP- exo-alpha-sialidase: hydroxymethylpyrimidine CHC09_RS02960 glutamate-- Cys (S)-3-amino-2- methylmalonate- CHC09_RS18445 H protein] N - glycine glycerophosphodiester glycerol cobalt-precorrin- 3-isopropylmalate 3-isopropylmalate aspartate-- acetyl-CoA C- acetyl-CoA C- carboxylesterase/ acetyl-CoA C- acetyl-CoA C- inositol phosphorylceramide cobM synthase: deacetylmycothiol [tRNA ] A: rpiA rpe glycine amidase: ribose deacetylase: CHC09_RS32950 a 2,3,4- CHC09_RS02960 an [L-cysteine adenylated- Cys dehydrogenase phosphodiesterase: tRNA(Asn) ligase: peptidase: synthase acyltransferase: acyltransferase: lipase family protein: acyltransferase: acyltransferase: synthase: CHC09_RS01975 a [cysteine kinase/ 2-[(2R,5Z)- D-glyceraldehyde cysteine ligase: a tRNA methylpropanoate semialdehyde lipoyl-L-lysine kinase: 6A reductase: dehydrogenase: dehydrogenase: CHC09_RS38115 desulfurase]-S- [ThiS sulfur- L-threonine degradation IV L-serine degradation Glu CHC09_RS17815 oxidase CHC09_RS11595 CHC09_RS26375 B: cysM CHC09_RS18545 CHC09_RS05725 CHC09_RS18545 CHC09_RS33810 CHC09_RS18545 CHC09_RS18545 [+ 3 isozymes] [+ 2 isozymes] diphosphate RS12910 saturated precorrin-5 desulfurase]-(S- phosphomethylpyrimidine mycothiol 3-phosphate CHC09_RS36700 D-ribose 5- D-xylulose dehydrogenase (aminomethyl- glpK CHC09_RS01110 CHC09_RS02830 CHC09_RS02830 CHC09_RS08610 7,8-dihydrofolate 2-carboxy-4- sulfanyl-L-cysteine carrier protein] dihydrolipoyl ThiO: thiO an L-aspartyl- 4-hydroxybenzoyl- (4Z,7Z,10Z,13Z,16Z)- 3-oxo-2-(cis-2'-pentenyl)- fatty acid sulfanyl) -[disordered- kinase: thiD synthase: [+ 3 isozymes] (CoA acylating) transferring): gcvP cobalt- 4-methyl-2- 10-(methylthio)- a peptide a peptide acetate S-sulfo-L-cysteine acetyl-CoA lauroyl-CoA acetate ADP-D-ribose MeOH (indol-3-yl)acetate acetyl-CoA N-acetylneuraminate an oligosaccharide a 1,2-diacyl-sn-glycerol an inositolphosphodihydroceramide 2 methylthiazol-5(2H 1-deoxy-D- γ-L-glutamyl- phosphate 5-phosphate dehydrogenase: propanoate [tRNA Asx ] acetyl-CoA docosapentaenoyl-CoA cyclopentane-1-(3-oxobutanoyl)-CoA precorrin- form scaffold monoglutamate mshD gly : mmsA thr pyruvate precorrin-6B oxopentanoate 2-oxodecanoate )-ylidene]ethyl xylulose-5- L-cysteine ser lpdA 6A synthase protein] complex HMP-PP cysteine phosphate mycothiol phosphate desulfurtrase: transketolase: L-asparagine L-serine a [glycine- sn-glycerol (deacetylating): glycine gln a [glycine-cleavage synthase: CHC09_RS02960 CHC09_RS07300 degradation I hydrogencarbonate ammonia-lyase: cleavage complex 3-phosphate CHC09_RS00475 oxidase low specificity L- complex H protein] N 6 - an organic a (5Z)-alkan- 3-[(4'-methylthio) a monocarboxylic a [protein] N-terminal- 3-oxo-(9Z)- a dimer of non-adjacent 2'- a [glycine-cleavage thiamine phosphate dxs an L-glutaminyl- [+ 3 isozymes] CHC09_RS29990 H protein] N 6 - α-bilirubin 2-chloromaleylacetate leukotriene-D4 methylsalicylate hydrogencarbonate H + nicotinate PRPP glutathione glycyl-glycine a 7,8-dihydrofolate ThiO: thiO threonine aldolase: 2-aminoprop- aminomethyldihydrolipoyl- glycerol-3- gly molecule 5-enoyl-CoA butyl]malate acid amide formyl-L-methionine hexadecenoyl-CoA deoxycytidine and thymidine in DNA SAM complex H protein] a sulfurated [sulfur carrier] precorrin-6A a [cysteine desulfurase]- synthase: 1-deoxy-D- [tRNA Gln ] L-arginine degradation III a 2,3,4- a thiocarboxy- glutathione asn CHC09_RS08175 2-enoate dihydrolipoyl- phosphate membrane carboxylesterase/ peptide acetyl-CoA C- carbonic anhydrase: nicotinate gamma- deoxyribodipyrimidine N 6 -octanoyl-L-lysine xylulose 5- Gln L-lysine cytochrome P450: 3-isopropylmalate maleylacetate [scaffold protein- dihydrofolate CHC09_RS10820 2-iminoacetate a tRNA D-sedoheptulose D-glyceraldehyde asparaginase: (arginine decarboxylase/ L-lysine glycine bilirubin oxidase: acyl-CoA oxidase: amidase: dipeptidase: lipoyl diphosphate RS36460 saturated precorrin-6A [ThiS-Protein] dehydrogenase: CHC09_RS33050 dehydrogenase: reductase: lipase family protein: deformylase: def acyltransferase: CHC09_RS00210 phosphoribosyltransferase: glutamyltransferase: photo-lyase: (2Fe-2S)] complex thiamine phosphate phosphate 7-phosphate 3-phosphate agmatinase pathway) oxidase CHC09_RS02880 CHC09_RS19155 CHC09_RS11595 CHC09_RS20275 synthase: lipA fatty acid reductase: reductase: AIR CHC09_RS35455 CHC09_RS42285 CHC09_RS02830 CHC09_RS43930 CHC09_RS33810 [+ 2 isozymes] CHC09_RS18545 [+ 3 isozymes] CHC09_RS24355 CHC09_RS29385 CHC09_RS37540 a [glycine-cleavage a cation RS42425 a cation synthase: acetaldehyde ThiO: thiO [+ 21 isozymes] an N-terminal L- (7Z)- γ-L-glutamyl- an unsulfurated CHC09_RS31870 asparaginase: gly arg MeOH salicylate formate acetyl-CoA H O CO NaMN L-cysteinyl-glycine a thymine in DNA a cytosine in DNA 5'-deoxyadenosine met complex H protein] CHC09_RS01110 thiazole synthase: a (2E,5Z)-alka- 7-(methylthio)-2- 5-chloro-3- leukotriene-E4 gly 2 2 [sulfur carrier] CHC09_RS10840 phosphomethylpyrimidine transaldolase: tal aminomethyltransferase: DHAP an alcohol biliverdin-IX-α a monocarboxylate methionyl-[protein] tetradecenoyl-CoA glycylglycine 6 [+ 4 isozymes] CHC09_RS10835 CHC09_RS16535 acetaldehyde 2-iminopropanoate pyruvoyl- glyoxylate 2,5-dienoyl-CoA oxoheptanoate oxoadipate N -lipoyl-L-lysine 10 synthase ThiC: factor 420 gcvP predicted precorrin-6B a [co-chaperone]- N -formyl-tetrahydrofolate biosynthesis asp dependent arginine a tetrahydrofolate CHC09_RS10850 polyglutamylation Glu D-erythrose dehydrogenase ABC [scaffold protein- thiamine 2-[(2R,5Z)- F6P decarboxylase: a sugar a sugar precorrin-6B (C 15 ) adenosylcobalamin salvage from cobinamide II 4-phosphate (acetylating): transporter (2Fe-2S)] complex phosphate 2-carboxy-4- an L-glutamyl- 6-O-α-mycolyl- RNase III mRNA a 3-O-acetylated methyltransferase: a tetrahydrofolate HMP-P oxidized CHC09_RS16910 CHC09_RS06450 2-aryl-2- 3-[(6'-methylthio) an organic 3-oxo-(5Z)- (11Z)-3-oxo- salicyl-6-hydroxy-2- Glu transketolase: L-glutamine agmatine trehalose 6- nicotinamide aminoacetone 4-methylcatechol 5,6-dihydrouracil 3-hydroxy- a [protein]-L-glutamine serotonin of a sugar thiamine- methylthiazol-5(2H coenzyme F -0 [tRNA ] L-phenylalanine degradation I (aerobic) methylmalonate hexyl]malate hydroperoxide tetradecenoyl-CoA hexadecenoyl-CoA processing rhamnogalacturonan I cyclohexene-on-oyl an acetyl-[acp] a malonyl-[acp] CHC09_RS01100 coenzyme420 F420-0:L- glu L-kynurenine predicted phosphate kinase: bifunctional )-ylidene]ethyl cobinamide a tRNA CHC09_RS07300 degradation II acetyl-CoA pyruvate phosphate pyrimidine reductase: acetyl-CoA C- acetyl-CoA C- transglutaminase: substrate rhamnogalacturonan carboxylesterase/ glutamate ligase: primary-amine arylmalonate 3-isopropylmalate alkyl hydroperoxide catechol 2,3- kynureninase: ribonuclease III: beta-ketoacyl-[acyl- CHC09_RS02640 hydroxymethylpyrimidine phosphate [+ 3 isozymes] agmatinase: trehalose- nicotinamidase: acyltransferase: acyltransferase: CHC09_RS32495 acetylesterase: lipase family protein: ABC precorrin-7 a [chaperone-ATP]- factor 420 biosynthesis ATP:cob(I)alamin (6R)-4a-hydroxy- oxidase: decarboxylase: dehydrogenase: reductase: dioxygenase: CHC09_RS09030 carrier-protein] synthase a sugar a sugar methionine kinase/ oxidizedCHC09_RS12255 D-glyceraldehyde speB phosphatase: CHC09_RS24360 CHC09_RS18545 kynU CHC09_RS18545 CHC09_RS02520 CHC09_RS06290 CHC09_RS33810 transporter [co-chaperone]- thiamine gln L-glutamine L-alanine tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin CHC09_RS14010 CHC09_RS19065 CHC09_RS02830 CHC09_RS37175 CHC09_RS19350 pyrimidine reductase: [+ 2 isozymes] RNase III II: CHC09_RS13890 5 adenosyltransferase: 6 a rhamnogalacturonan of a sugar precorrin-7 (C ) synthase: phosphomethylpyrimidine coenzyme F -1 3-phosphate Glycolysis glutamate degradation I otsB (3Z)-dodec- ala 3-hydroxyanthranilate (9Z)- a [protein] N -[(5-hydroxy-1H an mRNA fragment processing 6-hydroxy-2-cyclohexen- [scaffold protein- diphosphate 420 degradation IV dehydratase: 9-(methylthio)- 2-hydroxy-5-methyl-6- CHC09_RS24880 acetyl-CoA acetyl-CoA acetate salicyl alcohol ARP CHC09_RS06920 CHC09_RS03180 putrescine α, α'-trehalose methylglyoxal 3-enoyl-CoA tetradecenoyl-CoA -indol-3-yl)ethyl]-L-glutamine type I one-carboxylate an acetoacetyl-[acp] acyl-carrier protein methyltransferase: kinase: thiD F420-1:γ- isoleucine-- synthase nicotinate 2-arylpropanoate an alcohol uracil product mRNA (2Fe-2S)] complex 2-(2-carboxy-4- L-glutamate CHC09_RS13200 6-α-mycolate 2-oxononanoate oxohexa-2,4-dienoate CHC09_RS01100 methionine adenosylcobinamide glutamyl ligase: tRNA ligase: subunit gln a cation RS12330 a cation 5-amino-6-(D- HMP-PP methylthiazol-5- glycolysis III (from glucose) ala degradation I synthase: CHC09_RS13685 beta: gltD CTP synthase: precorrin-8x ribitylamino) yl)ethyl phosphate CHC09_RS12255 alanine CHC09_RS02950 adenosylcobinamide Glu uracil--L- oxidized isoleucine-- D-glucopyranose CHC09_RS36360 dehydrogenase: ald (6R)-L-erythro-5,6,7,8- L-erythro-7,8- 3-[(5'-methylthio) (R)-3- 5-cis, 7-trans- 3-(N-morpholino) 3-oxo-(7Z)- a 2-O-acetylated 3-oxo-2-(cis-2'-pentenyl)- dihydrofolate amidohydrolase: ile Glu pyruvate a quinone 5-aminolevulinate [EntF L-seryl- orotidine 5'- acetyl-CoA a sulfurated predicted precorrin-8X a [chaperone- tyrosine 4- thiamine phosphate coenzyme F -2 tRNA ligase: [+ 9 isozymes] tetrahydrobiopterin dihydrobiopterin ser pentyl]malate hydroxybutanoate a protein tetradecadienoyl-CoA propanesulfonate a type IV prepilin hexadecenoyl-CoA coenzyme A rhamnogalacturonan I cyclopentane-1-butanoyl-CoA SAM dethiobiotin 420 phosphate [sulfur carrier] ABC an [2Fe-2S] reductase: synthase: CHC09_RS00300 Glu alanine NAD-glutamate alkanesulfonate acetyl-CoA C- carrier protein] rhamnogalacturonan acetyl-CoA C- a sugar methylmutase: ADP]-[disordered- methylphenol CHC09_RS38170 an L-isoleucyl- glucokinase: pyruvate, NADPH:quinone porphobilinogen 3-isopropylmalate 3-hydroxybutyrate neuroendocrine orotate biotin a sugar cluster protein (S)-lactate CHC09_RS31870 dehydrogenase: ald dehydrogenase: L-serine acyl-CoA oxidase: prepilin peptidase: holo-ACP synthase: acetylesterase: transporter cobH form scaffold transferase: fbiC CHC09_RS10820 (R)-1-amino- Ile CHC09_RS08300 monooxygenase: acyltransferase: phosphoribosyltransferase: acyltransferase: serine [tRNA ] pyruvate water dikinase: reductase: synthase: dehydrogenase: dehydrogenase: convertase 1: CHC09_RS24535 CHC09_RS10930 synthase BioB: adenosylcobyrate Ile CHC09_RS03040 ammonia-lyase: CHC09_RS19155 CHC09_RS06290 of a sugar protein] complex 5-amino-5-(4- [+ 4 isozymes] thiamine phosphate 2-propanol O a tRNA CHC09_RS44395 CHC09_RS27345 CHC09_RS05155 CHC09_RS02830 CHC09_RS15870 CHC09_RS28850 CHC09_RS41970 CHC09_RS18545 a holo-[EntF pyrE CHC09_RS18545 CHC09_RS01295 hydrogenobyrinate hydroxymethyltransferase: D-glucopyranose 2-oxoglutarate 3-(N-morpholino) a cleaved type (5Z)- a rhamnogalacturonan 3-oxo-2-(cis-2'-pentenyl)- hydroxybenzyl)- synthase: -2-phosphate CHC09_RS29990 sulfite a peptide acetyl-CoA 3',5'-ADP L-seryl-carrier acetate an unsulfurated CHC09_RS03245 6-phosphate phosphoenol a semiquinone porphobilinogen 8-(methylthio)- acetoacetate a peptide a peptide 2-trans, 5-cis, 7-trans- propanal IV prepilin tetradecenoyl-CoA orotate PRPP type I cyclopentane-1-(3-oxohexanoyl)-CoA met 5'-deoxyadenosine biotin 6-(D-ribitylimino) a 7,8-dihydrofolate a 5-methyltetrahydrofolate CHC09_RS10840 pyruvate protein] [sulfur carrier] a sugar RS15315 a sugar glucose-6- pyruvate 2-oxooctanoate tetradecatrienoyl-CoA biotin RS19545 biotin (2S)-2- -5,6-dihydrouracil serine an [Fe-S cluster a [disordered- phospholactate hydroxymethyltransferase: phosphate biosynthesis form [Fe-S] cluster 7,8-didemethyl- thiamine adenosyl- leucine-- predicted hydrogenobyrinate 2-phospho-L-lactate CHC09_RS09555 leu isomerase: chaperone]-ATP 8-hydroxy-5- cobinamide 5,6-dimethylbenzimidazole a secondary a 2,3,4-saturated (5Z)- 3-oxo-(9Z)- D-xylulose 3-oxo-2-(cis-2'-pentenyl)- UDP-N-acetyl-α-D-muramoyl- ABC scaffold protein] phosphate tRNA ligase: CHC09_RS20305 pyrazinamide octanoyl-CoA 4-hydroxybenzoate 2-hydroxyisobutyramide octanoyl-CoA acetyl-CoA icosapentaenoate coenzyme A acetyl-CoA D-alanyl-D-alanine a,c-diamide guanylyltransferase: deazariboflavin thymidylate phosphate cys alcohol fatty acyl CoA tetradecenoyl-CoA octadecenoyl-CoA VibB coenzyme A 5-phosphate cyclopentane-1-hexanoyl-CoA L-alanyl-γ-D-glutamyl-L-lysine biotin RS22130 biotin a sugar a sugar thiamine- CHC09_RS07915 an L-leucyl- ammonium CO ATP transporter cobaltochelatase cofC synthase: fbiC synthase: GTP:adenosylcobinamide- nicotinate-nucleotide-- Secondary Metabolite Degradation acetyl-CoA C- 2 acetyl-CoA C- phosphoketolase: acyl-CoA synthetase: acetyl-CoA C- UDP-N-acetylmuramoyl- Leu F6P 4-hydroxybenzoate holo-ACP synthase: of a sugar subunit CobN: (2S)-lactyl-2- 7,8-didemethyl- CHC09_RS01470 phosphate kinase: dimethylbenzimidazole [tRNA ] cystathionine amidase: acyl-CoA oxidase: carbonyl reductase: acyl-CoA oxidase: acyl-CoA oxidase: amidase: acyltransferase: acyltransferase: CHC09_RS36840 CHC09_RS36460 acyltransferase: phosphate Leu 3-monooxygenase: carbamate kinase: tripeptide--D-alanyl- predicted CHC09_RS02640 phosphoribosyltransferase: a tRNA gamma-lyase: CHC09_RS10930 CHC09_RS00490 diphospho- 8-hydroxy-5- guanylyltransferase: 6-phosphofructokinase: anhydromuropeptides recycling I CHC09_RS11595 CHC09_RS19155 CHC09_RS18830 CHC09_RS19155 CHC09_RS19155 CHC09_RS31945 CHC09_RS11595 CHC09_RS18545 CHC09_RS38965 CHC09_RS18545 [+ 3 isozymes] [+ 18 isozymes] CHC09_RS18545 D- alanine ligase: thiamine salvage II 3-oxodecanoyl- (7Z)- a holo-[VibB aryl- 3-oxo-2-(cis-2'-pentenyl)- ABC 5'-guanosine deazariboflavin thiamine cobT CHC09_RS08240 Fatty Acid and Lipid Degradation N-acetylglucosamine CHC09_RS02670 carbamoyl 3',5'-ADP D-glyceraldehyde a sugar a sugar cob(II)yrinate CHC09_RS08555 pyrazine-2- (2E)-oct-2- a trans-2- (2E,5Z)- 2-hydroxy-2- acetyl-CoA carrier protein] acetyl phosphate icosapentaenoyl-CoA α CHC09_RS07860 transporter diphosphate GlcNAc-1,6- degradation I a ketone protocatechuate CoA phosphate hexadecenoyl-CoA 3-phosphate cyclopentane-1-(3-oxooctanoyl)-CoA UDP-N-acetyl- -D-muramoyl-L-alanyl- a,c-diamide 4-amino-2-methyl-5- NAD biosynthesis bifunctional 5,10- a (6S)-5- adenosylcobinamide- α-ribazole β-D-fructose 1,6- pyruvate carboxylate enoyl-CoA enoyl-CoA tetradecenoyl-CoA methylpropanoate of a sugar 2-phospho-L- anhMurNAc- γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine pyrimidinemethanol methylenetetrahydrofolate formyltetrahydrofolate GDP 5'-phosphate androstenedione degradation N-acetyl-D- predicted lactate transferase: I (from aspartate) valine--tRNA ligase: bisphosphate fatty acid β-oxidation I γ methylenetetrahydrofolate dehydrogenase/5,10- L-Ala- -D-Glu- glucosamine ABC bifunctional CHC09_RS12260 5-formyltetrahydrofolate CHC09_RS38110 DAP-D-Ala a sugar a sugar reductase [NAD(P)H]: metF methenyltetrahydrofolate acyl carrier protein metabolism val 6-phosphateN-acetylglucosamine- 5-dehydro-2- hydroxymethylpyrimidine cyclo-ligase: adenosylcobinamide- class II fructose- androst-4-ene-3,17-dione a 2,3,4-saturated α 4-hydroxybutanoyl- a [DNA]-3'- a 5'-phospho- + β 5-amino-4- 5 an oxidized transporter asp valine--tRNA ligase: coenzyme A acetoacetate homogentisate a 1,4- -D-glucan 4-guanidinobutyramide uroporphyrinogen-I butanoyl-CoA acetyl-CoA benzylbenzoate [EntB aryl- NAD a -D-mannoside PRPP N -methyltetrahydromethanopterin kinase/ cyclohydrolase: CHC09_RS04930 GDP bisphosphate 6-phosphate L-dopa L-saccharopine CoA deoxy-D-gluconate coenzyme A hydroxyl [DNA] imidazolecarboxyamide coenzyme F of a sugar oxidized L-aspartate CHC09_RS03400 fatty acid carrier protein] 420 CHC09_RS01560 an L-valyl- 3-ketosteroid-delta- 1,6-anhydro-N- deacetylase: nagA 1,4-alpha-glucan acetyl-CoA C- 5-dehydro-2- carboxylesterase/ DNA ligase: beta-mannosidase: adenine 5,10-methylene predicted phosphomethylpyrimidine coenzyme F -0 oxidase: a 5,10- a 5,10- ribazoletransferase: an acyl- Val aldolase: D-glucosamine acetoacetate homogentisate saccharopine uroporphyrinogen holo-ACP synthase: heme b biosynthesis 420 [tRNA ] 1-dehydrogenase: acetylmuramoyl-L- aromatic acid branching acyl-CoA oxidase: amidase: acyltransferase: lipase family protein: CHC09_RS41735 phosphoribosyltransferase: tetrahydromethanopterin Val acyl-CoA 6-phosphate decarboxylase: dehydrogenase: decarboxylase: deoxygluconokinase: CHC09_RS27080 ABC kinase: thiD CHC09_RS21470 methylenetetrahydrofolate methenyltetrahydrofolate CHC09_RS08560 carrier protein a tRNA CHC09_RS37320 alanine amidase: decarboxylase: 1,2-dioxygenase: CHC09_RS10930 a sugar a sugar I (aerobic) CHC09_RS16895 synthetase: protein GlgB: CHC09_RS19155 CHC09_RS11595 CHC09_RS18545 iolC CHC09_RS33810 [+ 2 isozymes] CHC09_RS31545 reductase: 2-iminosuccinate CHC09_RS18510 CHC09_RS06360 CHC09_RS18770 CHC09_RS01490 a holo-[EntB aryl- β transporter bifunctional 5,10- CHC09_RS23080 CHC09_RS26490 CHC09_RS17690 3-oxohexanoyl- 3',5'-ADP NMN AMP [DNA] a non glycosylated -D- CHC09_RS20365 HMP-P 3-ketosteroid-delta- CHC09_RS36460 4-maleyl- allysine 4-hydroxycrotonyl- 5-dehydro-2-deoxy-D- benzyl alcohol benzoate carrier protein] AICAR of a sugar uroporphyrinogen-III methylenetetrahydrofolate adenosylcobalamin Fermentation triose-phosphate acetone Glu 4-guanidinobutanoate coproporphyrinogen I CoA sugar acceptor mannopyranose a reduced 5,10-methylene- an oxidized quinolinate 1-dehydrogenase: [+ 18 isozymes] β dopamine acetoacetate a glycogen CoA gluconate 6-phosphate predicted uroporphyrinogen 5-(2-hydroxyethyl) dehydrogenase/5,10- 5'-phosphate ACP holo-ACP synthase: N-acetyl- -D- L-alanyl-γ-D- α coenzyme F tetrahydromethanopterin bifunctional synthase NadA: isomerase: -D-glucosamine 420 coenzyme F phosphodiesterase: CHC09_RS10930 CHC09_RS17590 glucosamine-1,6- glutamyl-meso-2,6- ABC decarboxylase: hydroxymethylpyrimidine -4-methylthiazole 420 CHC09_RS08480 methenyltetrahydrofolate alanine-- pyruvate fermentation CHC09_RS07345 a 2,3,4-saturated 6-phosphate a sugar a sugar D-glyceraldehyde anhydro-N-acetyl- diaminopimeloyl- transporter CHC09_RS01490 kinase/ cyclohydrolase: CHC09_RS13180 [+ 3 isozymes] tRNA ligase: to ethanol I DHAP androsta-1,4-diene-3,17-dione fatty acyl CoA 3-phosphate β-D-muramate D-alanine 6-trans- 2-(4-hydroxyphenyl) 3-oxo- an apo-[LYS2 L- all-trans- 2-amino-6-[1-hydroxyethyl]- of a sugar coproporphyrinogen III phosphomethylpyrimidine quinolinate CHC09_RS01560 CHC09_RS31330 crotonyl-CoA 7,8-dihydro- 3-ethylmalate a 1,4-α-D-glucan 3-oxo-4-pregnene- oxaloacetate α-D- a carboxylic ester isovalerate ∆ 3 2 glutathione hypoglycin A octaprenyl 4-hydroxybenzoate predicted glyceraldehyde- 3-ketosteroid-9- -cis-∆ -trans- beta-N- LD- 8-oxoguanine 20-carboxyl-CoA tridecenoyl-CoA -2-oxoacetate palmitoyl-CoA 2-aminoadipyl- coenzyme A 7-methyl-7,8-dihydropterin kinase: thiD a reduced a 10- adenosylcobalamin alanine-- pyruvate acyl-CoA 1,4-alpha-glucan glucopyranose ATP carboxylesterase/ 4-methyl-5-(2- nicotinate- ala 3-phosphate acetylhexosaminidase: carboxypeptidase: crotonyl-CoA 8-oxoguanine 3-isopropylmalate acetyl-CoA C- phosphoenolpyruvate benzoylformate acetyl-CoA C- carrier-protein] acetate--CoA gamma- diphosphate 4-hydroxybenzoate 2-amino-4-hydroxy-6- ABC coenzyme F formyltetrahydrofolate tRNA ligase: alpha-hydroxylase: dehydrogenase: enoyl-CoA F6P branching acyl-CoA oxidase: 1-phosphate holo-ACP synthase: a sugar a sugar phosphooxyethyl) 420 acyl-carrier protein dehydrogenase: carboxylase/ acyltransferase: lipase family protein: ligase: acs transporter HMP-PP nucleotide CHC09_RS16950 CHC09_RS14440 isomerase: a (3Z)-alk-3- CHC09_RS23885 CHC09_RS14975 deaminase: dehydrogenase: acyltransferase: carboxykinase (GTP) decarboxylase: glucose-1-phosphate CHC09_RS10930 glutamyltransferase: octaprenyltransferase: hydroxymethyldihydropteridine thiazole CHC09_RS09990 an L-alanyl- formate C- reductase: protein GlgB: CHC09_RS19155 CHC09_RS18545 CHC09_RS33810 a holo-[LYS2 L- of a sugar diphosphorylase gap CHC09_RS36230 enoyl-CoA [+ 2 isozymes] LD- CHC09_RS29545 CHC09_RS02830 CHC09_RS18545 : CHC09_RS04425 CHC09_RS21170 adenylyltransferase: CHC09_RS29385 ubiA diphosphokinase: folK folate transformations I [tRNA Ala ] acetyltransferase: 3-ketosteroid-9- [+ 36enoyl-CoA isozymes] ccrA CHC09_RS17690 2-aminoadipyl- 3',5'-ADP isovaleryl-CoA AMP diphosphate 3-octaprenyl-4- [1-(2-amino-7-methyl-4-oxo- protoporphyrinogen IX (carboxylating) carboxypeptidase: 3,22-dioxochol- 2-trans-6-trans- phosphoenol myristoyl-CoA acetyl-CoA glgC a carboxylate an alcohol L-cysteinyl-glycine hypoglycin B Ala alpha-hydroxylase: 1,6-anhydro-N- (2S)- urate 2-oxovalerate α thiamine phosphate : nadC a tRNA pflB 13-DPG a 2,3,4-saturated hydratase: a trans-2- starch 4-hydroxybenzaldehyde ADP- -D-glucose carrier-protein] hydroxybenzoate 7,8-dihydro-3H-pteridin- CHC09_RS16960 acetyl-β-muramate CHC09_RS24965 ethylmalonyl-CoA 4-en-24-oyl-CoA tridecadienoyl-CoA pyruvate a sugar RS14805 a sugar protoporphyrinogen synthase: a tetrahydrofolate fatty acyl CoA CHC09_RS17360enoyl-CoA L-alanyl-γ-D- 6-yl)]ethyl diphosphate CHC09_RS10820 NaMN menaquinol-9 biosynthesis phosphoglycerate 9α-hydroxyandrosta- oxidase: hemG phosphopantothenate biosynthesis I acetyl-CoA formate enoyl-CoA glutamyl-meso- thiamine phosphate kinase: pgk 1,4-diene-3,17-dione acetyl-CoA acetyl-CoA C- hydratase: diaminopimelate Man GlcNAc - nicotinate-nucleotide α 6-cis- (3R)-3-hydroxy-2-oxo- a [protein]- an organic a single a ribonucleoside 9 2 a single- an L-methionyl- protoporphyrin IX synthase: acetaldehyde acyltransferase: CHC09_RS17515 N-acetyl-D- acryloyl-CoA methylglyoxal cyanophycin a 1,4- -D-glucan a cytosine in DNA hexanoyl-CoA acetyl-CoA (S)-4-amino-5- glu a 10- 7-hydroxylaurate demethylmenaquinol-9 a protein a tRNA L-cysteine hydroperoxide [protein] (isomer Met RS19565 a sugar 3-methyl-2-oxobutanoate adenylyltransferase: formyltetrahydrofolate asn 3-phospho- tridecenoyl-CoA 4 phosphooxybutanoate oxopentanoate stranded DNA triphosphate stranded RNA formyltetrahydrofolate [initiator tRNA ] a sugar CHC09_RS10840 dehydrogenase CHC09_RS18545 muramate 6- crotonyl-CoA 1,4-alpha-glucan acetyl-CoA C- peroxiredoxin: 9A B ) polyribonucleotide acyl-CoA synthetase: ferrochelatase: CHC09_RS38250 deformylase: purU bifunctional D-glycerate glyoxalase: DNA methylase: trypsin: phosphoserine glutamyl-tRNA DNA primase: 1,2,3 alpha-1,2-1,2,3 methionyl-tRNA (acetylating): phosphate carboxylase/ cyanophycinase: branching acyl-CoA oxidase: acyltransferase: CHC09_RS14605 nucleotidyltransferase: CHC09_RS18570 CHC09_RS07055 3-methyl-2-oxobutanoate nicotinate adenine demethylmenaquinone an L-asparaginyl- phosphoglycerate 3-hydroxy-9,10-secoandrosta- CHC09_RS36385 CHC09_RS41345 CHC09_RS03600 transaminase: reductase: CHC09_RS24445 mannosidase: formyltransferase: thiamine Asn CHC09_RS16910 a (3S)-3- N-acetylmuramic β reductase: CHC09_RS31505 protein GlgB: CHC09_RS19155 CHC09_RS18545 [+ 4 isozymes] CHC09_RS01985 [+ 18 isozymes] deferrochelatase/ hydroxymethyltransferase: dinucleotide methyltransferase/2- [tRNA ] mutase: 1,3,5(10)-triene-9,17-dione a 3-oxoacyl-CoA superpathway of -D- [+ 12 isozymes] [+ 4 isozymes] [+ 2 isozymes] CHC09_RS27205 CHC09_RS05170 [+ 3 isozymes] CHC09_RS39160Man GlcNAc - an N-formyl- CHC09_RS31190 Asn hydroxyacyl-CoA acid 6- CHC09_RS17690 3-oxooctanoyl- an L-glutamyl- an ssDNA/RNA β-D- 8 2 a nucleoside a single- peroxidase EfeB: phosphate panB methoxy-6-polyprenyl-1,4- tRNA CHC09_RS05260 glucuronosides degradation ccrA [L-Asp(4-L- a 5-methylcytosine 2-trans,6-cis- 4-phosphooxy- an alcohol a protein disulfide [protein] (isomer L-methionyl- a tetrahydrofolate a sugar RS27635 a sugar NAD+ synthetase, acetaldehyde phosphate (R)-methylmalonyl- (R)-lactate a peptide a peptide CoA Glu diphosphate stranded RNA AMP diphosphate 7-hydroxylauroyl-CoA a 10- benzoquinol methylase a GlgE-glycogen [tRNA ] primer hybrid mannopyranose met CHC09_RS28240 thiamine- NAD+ synthase: 2-phospho- Arg)] dipeptide in DNA tridecadienoyl-CoA L-threonine 8A B ) [initiator tRNA ] 2-dehydropantoate glutamine formyltetrahydrofolate UbiE: CHC09_RS26645 etherase: murQ a β-D-glucuronoside CoA 1,2,3 2,3 phosphate kinase: CHC09_RS08875 NAD(P)- D-glycerate N-acetyl-D- ferroheme b dependent: methionine menaquinol-9 3,4-dihydroxy-9,10-secoandrosta- 3-hydroxybutyryl- CHC09_RS02640 ketopantoate reductase: dependent alcohol glucosamine CHC09_RS08875 synthase: aspartate-- phosphopyruvate 1,3,5(10)-triene-9,17-dione 3-hydroxyacyl-CoA CoA epimerase: a sugar RS28000 a sugar thiamine CHC09_RS25500 bifunctional 5,10- a (6S)-5- dehydrogenase: 6-phosphate 3-oxo- N-acetyl-D- Man GlcNAc - CHC09_RS06920 hydratase: dehydrogenase: CHC09_RS36230 α 8 2 + methylenetetrahydrofolate formyltetrahydrofolate tRNA ligase: D-glucopyranuronate a DNA segment benzaldehyde α-D-ribofuranose a 1,4- -D-glucan maltose a proteinogenic 18-hydroxyoleate diphosphate 2-dehydropantoate NAD CHC09_RS34685 CHC09_RS33130 N-acetylglucosamine- prephenate fMet a protein a tRNA precursor a PII protein UTP (6Z,9Z,12Z,15Z,18Z,21Z) galactosamine [protein] (isomer leukotriene-C4 palmitoyl-CoA a ferrocytochrome b methionine 5-formyltetrahydrofolate CHC09_RS31385 CHC09_RS36230 amino acid 5 2-reductase: dehydrogenase/5,10- [+ 2 isozymes] 6-phosphate ribokinase: 1,4-alpha-glucan alpha-glucosidase/ -tetracosahexaenoyl-CoA 6-phosphate 8A B ) acyl-CoA synthetase: synthase: cyclo-ligase: phosphopyruvate benzaldehyde prephenate formylmethionine Clp protease: ribonuclease D: [protein-PII] acetyl-CoA C- N-acetylglucosamine- 1,2,3 alpha-1,2-2,3 gamma- acyl-CoA desaturase: CHC09_RS33490 5,6-dimethylbenzimidazole methenyltetrahydrofolate aspartate-- (1E,2Z)-3-hydroxy-5,9,17- deacetylase: nagA recombinase CHC09_RS01660 branching alpha-galactosidase: CHC09_RS18570 heme a biosynthesis CHC09_RS02950 CHC09_RS04930 asp ethanol hydratase: dehydrogenase: dehydratase: deformylase: CHC09_RS39125 CHC09_RS01505 uridylyltransferase: acyltransferase: 6-phosphate mannosidase: glutamyltransferase: CHC09_RS12840 biosynthesis I (aerobic) cyclohydrolase: tRNA(Asn) ligase: trioxo-4,5:9,10-disecoandrosta- a (3R)-3- RecA: recA ribokinase: protein GlgB: CHC09_RS14790 [+ 18 isozymes] a sugar RS25860 a sugar β-alanine bifunctional 5,10- CHC09_RS11385 D-glucosamine CHC09_RS05430 CHC09_RS22765 CHC09_RS22490 [+ 6 isozymes] a nucleoside 5'- CHC09_RS02440 CHC09_RS18545 deacetylase: nagA CHC09_RS39160Man GlcNAc - CHC09_RS29385 [+ 4 isozymes] (R)-pantoate bifunctional 5,10-CHC09_RS01560 CHC09_RS08610 an L-aspartyl- 1 (10),2-dien-4-oate hydroxyacyl-CoA aldehydo-D-glucuronate CHC09_RS17690 a tRNA D-galactosamine β-D- 7 2 an α-(γ-L-glutamyl) triacylglycerol 6-phosphate a DNA segment keto- CHC09_RS03015 α [+ 2 isozymes] a uridylylated docosahexaenoyl- serine methylenetetrahydrofolate asp α formate met a (1,6)- -D-glucosyl- a peptide a peptide monophosphate acetyl-CoA acetate [protein] (isomer leukotriene-D4 a ferricytochrome b palmitoleoyl-CoA riboflavin methylenetetrahydrofolate [tRNA ] phosphoenol benzoate -D-ribose 6-phosphate mannopyranose -L-amino acid 5 AMP diphosphate 18-hydroxyoleoyl-CoA ferroheme b degradation phosphoglucosamine glucuronate in reverse phenylpyruvate α D-glucopyranose PII protein CoA hydroxymethyltransferase: dehydrogenase/5,10- asp pyruvate (1,4)- -glucan 7A B ) protoheme IX bifunctional dehydrogenase/5,10- a 5,10- tRNA orientation 5-phosphate 1,2,3 2 pantoate--beta-alanine CHC09_RS03245 methenyltetrahydrofolate folate polyglutamylation mutase: isomerase: a sugar farnesyltransferase: riboflavin kinase/ methenyltetrahydrofolate methenyltetrahydrofolate pyruvate RS24000 a sugar ligase: CHC09_RS21485 cyclohydrolase: a triglyceride CHC09_RS10900 CHC09_RS18005 CHC09_RS07295 FAD synthetase: ribF serine cyclohydrolase: kinase: pyk 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo- triacylglycerol CHC09_RS01560 (2Z,4Z)-2-hydroxyhexa-2,4-dienoate ADP-D-glycero-β- a debranched α a 5'-half-tRNA Man GlcNAc - ferroheme o di-trans,poly-cis-undecaprenyl FMN hydroxymethyltransferase: CHC09_RS01560 a tetrahydrofolate D-glucosamine D-fructuronate (3S,5S)-3,5- an (1,5)- (6Z,9Z,12Z,15Z,18Z,21Z) 7 2 octahydro-1H-inden-4-yl]propanoate lipase: long chain ethanol squalene D-threo-isocitrate α an α-limit dextrin a 3'-half-tRNA isobutanoate 18-hydroxystearate (R)-pantothenate phosphate biosynthesis CHC09_RS09555 D-manno-heptose -limit dextrin L-arabinan -tetracosahexaenoyl-CoA molecule with propanoyl-CoA phosphate protein (isomer pyruvate acyl-CoA synthetase: CHC09_RS23155 1-phosphate polyphosphate diaminohexanoate molecule with a tRNA precursor CTP ATP flavin reductase: tyr tyrosine-- isocitrate ADP-L-glycero-D- glycogen/starch/ L-erythro-3,5- alpha-L- 4-alpha- a 2',3'-cyclic phosphate 7A B ) acetate--CoA acyl-CoA synthetase: a cation RS33645 a cation heme A synthase: polyphosphate catalase: squalene-- a 5'-OH end 1,2,3 alpha-1,2-1 (2E,6E)-farnesyl CHC09_RS32940 serine bifunctional tRNA ligase: CHC09_RS36460 triacylglycerol UDP-N- manno-heptose- alpha-glucan diaminohexanoate arabinofuranosidase: acyl-CoA oxidase: phosphate end CCA tRNA CHC09_RS18570 CHC09_RS07280 pantothenate kinase: IPP a 5,10- CHC09_RS01060 hopene cyclase: dehydrogenase glucanotransferase: 2'-5' RNA ligase: acyltransferase PlsX: mannosidase: ligase: acs diphosphate hydroxymethyltransferase: folylpolyglutamate CHC09_RS30755 [+ 5 isozymes] lipase: acetylglucosamine kinase 2: ppk2 6-epimerase: phosphorylase: CHC09_RS44190 CHC09_RS19155 nucleotidyltransferase: CHC09_RS21460 di-trans,poly-cis- [+ 9 isozymes] a 5-methyltetrahydrofolate an L-tyrosyl- [+ 2 isozymes] CHC09_RS10335 (NADP(+)): dehydrogenase: malQ CHC09_RS03300 CHC09_RS02525 CHC09_RS39160 [+ 18 isozymes] methylenetetrahydrofolate CHC09_RS03245 Tyr [+ 2 isozymes] Man GlcNAc - ferroheme i synthase/ a 10- [tRNA ] (S)-4-hydroxy-2-oxohexanoate 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo- CHC09_RS30610 diphosphorylase/ D-mannonate CHC09_RS11225 CHC09_RS09650 CHC09_RS00715 CHC09_RS21220 [+ 11 isozymes] a α-limit dextrin a ligated tRNA β-D- 6 2 isobutanoyl-CoA AMP diphosphate a tRNA CHC09_RS23040 decaprenylcistransferase: Tyr β (2E,6Z,9Z,12Z,15Z,18Z,21Z) propanoyl phosphate FMNH serine dihydrofolate a tRNA a 1,2-diglyceride glucosamine-1- long chain acetaldehyde hop-22(29)-ene ADP-L-glycero- - α-D-glucopyranose (S)-5-amino-3- α-L- [protein] (isomer containing a AMP diphosphate 18-hydroxystearoyl-CoA (R)-4'-phosphopantothenate uppS 2 formyltetrahydrofolate octahydro-1H-inden-4-yl]propanoyl-CoA 2-oxoglutarate with short branches with a 2'-5' linkage mannopyranose a sugar RS16055 a sugar methylenetetrahydrofolate bifunctional D-manno-heptose 1-phosphate arabinofuranose -tetracosaheptaenoyl-CoA 6A B ) heme A synthase: hydroxymethyltransferase: synthase: bifunctional phosphate N- polyphosphate oxohexanoate 1,2 1 3' CCA end isoprenyl 5,6-dimethylbenzimidazole reductase [NAD(P)H]: metF D-altronate/D- CHC09_RS07280 CHC09_RS09555 CHC09_RS38115 folylpolyglutamate acetyltransferase: transferase: synthase: bluB mannonate pyridoxal 5'-phosphate salvage I synthase/ glmU di-trans,octa-cisCHC09_RS38440 5-hydroxy-3-[(3aS,4S,5R,7aS)- dehydratase: (S)-3- GlcMan GlcNAc Man GlcNAc - a 10- hydroxyferroheme i 4,5- 9 2 a [protein]- 8 2 a 5,10- dihydrofolate tryptophan- 1-propanal pyruvate bifunctional N- histidinol 2'-deoxyribose 5,6-dihydrothymine L-threo-3- a [protein]-L-lysine a peptidoglycan a lipid II 16-hydroxypalmitate a sugar RS19640 a sugar menaquinol-10 biosynthesis -undecaprenyl 5,6-dimethylbenzimidazole menaquinol-11 biosynthesis a tetrahydrofolate 7a-methyl-1,5-dioxo-octahydro- a 2-acylglycerol CHC09_RS14745 MeOH propanoyl-CoA aminobutanoyl- 3-oxopropanoate -[protein] [protein] (isomer formyltetrahydrofolate- methylenetetrahydrofolate synthase: -tRNA biotin ATP dihydroxyphthalate pyrimidine reductase: phenylserine L-glutamine diphosphate pyridoxine pyridoxamine 1H-inden-4-yl]propanoyl-CoA acetylglucosamine- ribokinase: CoA malonic 4,5- alpha-1,2- transglutaminase: 8A B ) peptidoglycan 4a-carbinolamine acyl-CoA synthetase: menaquinol-7 biosynthesis propanal 2-dehydro-3- histidinol catalase: low specificity L- 1,2,3 alpha-1,2-1,2 all-trans- bifunctional CHC09_RS38115 ligase: trpS 1-phosphate CHC09_RS01660 3-aminobutyryl-CoA CHC09_RS09030 mannosidase: glycosyltransferase: 4a-hydroxytetrahydrobiopterin all-trans- undecaprenyl- dehydrogenase: deoxy-D-gluconate dehydrogenase: acyl-CoA oxidase: biotin--[acetyl-CoA- semialdehyde dihydroxyphthalate CHC09_RS32495 mannosidase: CHC09_RS18570 2-carboxy-1,4- 2-carboxy-1,4- pyridoxal pyridoxal folylpolyglutamate tryptophan- CHC09_RS01060 threonine aldolase: all-trans- decaprenyl diphosphate undecaprenyl a 10- Trp uridyltransferase/ CHC09_RS19155 ribokinase: carboxylase] ligase: ammonia-lyase: reductase: pyrimidine reductase: CHC09_RS39160 [+ 2 isozymes] CHC09_RS37030 dehydratase: [+ 18 isozymes] 2-carboxy-1,4- naphthoquinol naphthoquinol kinase PdxY: kinase PdxY: a tRNA CHC09_RS16910 2-dehydro-3- hisD [+ 2 isozymes] decarboxylase: CHC09_RS08175 D-glucosyl- Man GlcNAc - a protein with an CHC09_RS39160Man GlcNAc - di-trans,octa-cis diphosphate diphosphate synthase/ -tRNA glucosamine- CHC09_RS21240 CHC09_RS24880 8 2 β 7 2 CHC09_RS13200 Peptide RS29240 Peptide ferroheme a heptaprenyl phosphatase: formyltetrahydrofolate CHC09_RS03015 CHC09_RS04450 CHC09_RS22050 CHC09_RS42485 6 -D- naphthoquinol CHC09_RS40485 CHC09_RS40485 (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy- deoxygluconokinase: biotinyl-5'- gly benzaldehyde α(1->3)- α- [protein] (isomer N -(γ-glutamyl)- [protein] (isomer -undecaprenyl a peptidoglycan 10 diphosphate CHC09_RS24905 thioredoxin dihydrofolate ligase: trpS an L-tryptophanyl- propanoyl-CoA a 1-monoglyceride 1-phosphate his formaldehyde acryloyl-CoA 2-deoxy-D-ribose thymine mannopyranose an N - AMP diphosphate 16-hydroxypalmitoyl-CoA DMKH2-10 DMKH2-11 7a-methyl-1-oxo-octahydro-1H CHC09_RS00065 adenylate crotonyl-CoA 3-hydroxypropanoate protocatechuate D-mannose 8A B ) L-lysine crosslink 7A B ) diphosphate pathway pyridoxine synthase: [tRNA Trp ] acetyltransferase: 5-phosphate 1,2,3 1,2 1,2 1,2 formyldihydrofolate di-trans,octa-cis- pyridoxamine -inden-4-yl]prop-2-enoyl-CoA demethylmenaquinol-7 5'-phosphate 5'-phosphate CHC09_RS38115 trp CHC09_RS30580 bifunctional undecaprenyl phosphate bifunctional β KDGP an oxidized pyridoxamine 5'- pyridoxamine 5'- pyridoxal oleate -oxidation N-acetyl-α-D- a sugar RS06210 a sugar demethylmenaquinone demethylmenaquinone a 5,10- lipoate biosynthesis menaquinol-6 biosynthesis bifunctional thioredoxin phosphate oxidase: phosphate oxidase: γ (5E)-3-oxo- Man GlcNAc - Man GlcNAc - Man GlcNAc - lipid II (meso pyridoxal methylenetetrahydrofolate glucosamine 2-dehydro-3- α (S)-2- a [DNA]-3'- a 5'-phospho- all-trans- dihomo - 6 2 7 2 7 2 demethylmenaquinone methyltransferase/2- methyltransferase/2- CHC09_RS39730 CHC09_RS39730 and incorporation I glycerol (2E,5Z)- -amylose hydroxyquinol xylan H O a peptide with a acetoacetate seleno-L- kinase PdxY: 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a- 1-phosphate phosphoenol hydroxyl [DNA] retinyl palmitate linolenoyl-CoA 2 dodec-5- [protein] (isomer [protein] (isomer [protein] (isomer diaminopimelate methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- deoxyphosphogluconate dGDP hydroxyglutarate leader sequence homocysteine methyltransferase/2- [+ 6 isozymes] [+ 6 isozymes] CHC09_RS40485 demethylmenaquinol-6 methyl-1-oxo-octahydro-1H-inden- tetradecenoyl-CoA pyruvate 1,4-alpha-glucan L-2- alpha-xylosidase: ATP- carboxylesterase/ acyl-CoA enoyl-CoA 6A B ) 7A B ) 7A B ) containing) acetoacetate- threonine-- UDP-N- aldolase: CHC09_RS00070 hydroxyquinol acetyl-CoA C- signal 1,2 alpha-1,2-1 1,2,3 alpha-1,2-3 1,2 1,2alpha-1,2- peptidoglycan methoxy-6-polyprenyl-1,4- benzoquinol methylase thioredoxin- benzoquinol methylase an octanoyl-[acp] bifunctional 4-yl]-3-hydroxypropanoyl-CoA pyruvate branching hydroxyglutarate CHC09_RS39175 dependent lipase family thioesterase: -CoA ligase: 5-methyltetrahydropteroyltriglutamate- a sugar RS00405 a sugar adenosylcobalamin tRNA ligase: acetylglucosamine D-glyceraldehyde 1,2-dioxygenase: acyltransferase: peptidase I: lepB mannosidase: mannosidase: mannosidase: glycosyltransferase: benzoquinol methylase UbiE: CHC09_RS26645 disulfide UbiE: CHC09_RS26645 lipoate-protein demethylmenaquinone enoyl-CoA pyruvate kinase: pyk protein GlgB: oxidase: alpha-xylosidase: DNA protein: CHC09_RS23415 CHC09_RS12230 - homocysteine S-methyltransferase: salvage from cobalamin menaquinol-8 biosynthesis CHC09_RS31645 diphosphorylase/ 3-phosphate CHC09_RS43925 CHC09_RS18545 [+ 3 isozymes] CHC09_RS39160Man GlcNAc CHC09_RS39160Man GlcNAc CHC09_RS39160Man GlcNAc - lipid II (meso di-trans,octa-cisCHC09_RS37030 UbiE: CHC09_RS26645 reductase: ligase B: methyltransferase/2- hydratase: CHC09_RS17690 CHC09_RS35930 [+ 4 isozymes] (3E)-dec-3- β-D- 5 2 β-D- 6 2 β-D- 6 2 CHC09_RS12950 menaquinol-10 menaquinol-11 CHC09_RS13065 ligase: ligC CHC09_RS33810 acetyl-CoA a leader sequence a peptide -[protein] [protein] (isomer diaminopimelate -undecaprenyl a [lipoyl-carrierCHC09_RS08600 threonine- glucosamine-1- dGTP pyruvate 2-maleylacetate di-homo-γ- mannopyranose -[protein] mannopyranose AMP diphosphate acetoacetyl-CoA trxB PLP methoxy-6-polyprenyl-1,4- thr 3-[(3aS,4S,5R,7aS)-5-hydroxy- CHC09_RS17360 3E,5Z- amylopectin 2-oxoglutarate α-D-xylopyranose [DNA] palmitate a retinol enoyl-CoA mannopyranose menaquinol-7 cob(I)alamin protein] N 6 - -tRNA phosphate N- (isomer 5A ) (isomer 6A ) 6A B ) containing) diphosphate SeMet demethylmenaquinol-8 benzoquinol methylase enoyl-CoA tetradecadienoyl-CoA linolenate 1,2 1,2,3 1,2 2 a sugar RS01160 a sugar ATP:cob(I)alamin octanoyl-L-lysine ligase: thrS an L-threonyl- 7a-methyl-1-oxo-octahydro-1H- acetyltransferase: bifunctional UbiE: CHC09_RS26645 hydratase: adenosyltransferase: lipoyl Thr inden-4-yl]-3-oxopropanoyl-CoA acyl-CoA glmU a reduced demethylmenaquinone menaquinol-6 [tRNA ] Thr CHC09_RS17515 thioesterase: CHC09_RS03180 synthase: a tRNA a glucosylated adenosyl- a dimer of Man GlcNAc - thioredoxin methyltransferase/2- S-(hydroxymethyl) 8 2 a dimer of non-adjacent a 1-phosphatidyl- decaprenyl-diphospho-N- UDP-N-acetyl- adenosylcobalamin lipA CHC09_RS23415 bifunctional N- D-galacturonate degradation I a D-hexose (S)-malate an acyl-CoA H O propanoyl-CoA H O a RNA-DNA hybrid maltoheptaose 2-methylbutanoate phosphoenol glycogenin cobyrinate 2 2 non-adjacent [protein] (isomer α-D-glucosamine methoxy-6-polyprenyl-1,4- a [lipoyl-carrier (S)-3-hydroxy-(5Z) acetylglucosamine- dADP mycothiol 2'-deoxycytidines in DNA 1D-myo-inositol acetylmuramoyl-pentapeptide Peptide RS42095 Peptide 3-[(3aS,4S,5R,7aS)-5-hydroxy- [+ 4 isozymes] pyruvate 1,4-alpha-glucan fumarate hydratase: a,c-diamide S-(hydroxymethyl) acyl-CoA acyl-CoA ribonuclease HI: thymidines in DNA 8A B ) 1-phosphatidylinositol alpha-glucosidase/ acetate- undecaprenyldiphospho- benzoquinol methylase 6 -tetradecenoyl-CoA 1-phosphate aldehydo-D- 1,2,3 alpha-1,2-1,3 deoxyribodipyrimidine protein]-N - acetyl-CoA glucokinase: branching cobyric acid deoxyribodipyrimidine alpha-galactosidase: UbiE: CHC09_RS26645 7a-methyl-1-oxo-octahydro- (3E,5Z)- pyruvate CHC09_RS35120 mycothiol thioesterase: thioesterase: CHC09_RS00370 mannosidase: phosphodiesterase: -CoA muramoylpentapeptide beta-N- lipoyl-L-lysine uridyltransferase/ galacturonate CHC09_RS08300 photo-lyase: photo-lyase: CHC09_RS14790 1H-indene-4-carboxylate tetradecadienoate glucuronate kinase: pyk protein GlgB: class II fumarate synthase: dehydrogenase: CHC09_RS23415 CHC09_RS30345 [+ 2 isozymes] CHC09_RS00725 ligase: acs acetylglucosaminyltransferase: menaquinol-8 ser glucosamine- CHC09_RS39160Man GlcNAc CHC09_RS37540 D-myo-inositol isomerase: CHC09_RS17690 CHC09_RS23500 CHC09_RS24395 a nucleoside 5'- CHC09_RS37540 β-D- 5 2 a 1,2-diacyl- [+ 2 isozymes] murG serine--tRNA ligase: 1-phosphate D-hexose 6- hydratase: aspA [+ 4 isozymes] [+ 4 isozymes] DNA -[protein] 1,2-cyclic 2-methylbutanoyl- decaprenyl-pyrophosphoryl- a sugar RS37705 a sugar CHC09_RS18005 dATP pyruvate a glycogen monophosphate mannopyranose a cytosine in DNA sn-glycerol maltohexaose AMP diphosphate CHC09_RS22785 an L-seryl- acetyltransferase: phosphate fumarate adenosylcobyrate S-formylmycothiol a carboxylate propanoate a thymine in DNA (isomer 5A ) phosphate D-glucopyranose CoA UDP (N-acetylglucosamine)-N- D-tagaturonate 1,2 [tRNA ser ] CHC09_RS30580 acetylmuramyl-(pentapeptide) a tRNA ser tagaturonate superpathway of adenosine Nucleoside and Nucleotide Biosynthesis UDP-N-acetyl- inosine-5'-phosphate biosynthesis I Peptide RS21340 Peptide superpathway of guanosine pyrimidine deoxyribonucleotides de novo biosynthesis I adenine and adenosine salvage III α-D-glucosamine reductase: (S)-2-oxo-4- Man GlcNAc - nucleotides de novo biosynthesis I S-(hydroxymethyl) a long-chain (+)-7-epi- 9 2 a 2-oxo nucleotides de novo biosynthesis I CHC09_RS18000 geranyl chorismate 2-deoxygluconate H O H O 3-sulfocatechol FMNH NAD + a 5-L-glutamyl- maltopentaose phenylacetate UDP-N-acetylglucosamine asp hydroxy-4-carboxy- 2 2 2 [protein] (isomer sarcosine a tetrahydrofolate an amino acid diphosphate bacillithiol acyl-CoA jasmonoyl-CoA [peptide] carboxylate UDP CTP AIR 1-carboxyvinyltransferase: 5-ureidoimidazoline chorismate mutase: 2-deoxy-D- S-(hydroxymethyl) acyl-CoA acyl-CoA catechol 2,3- NADPH-dependent 9A B ) alpha-glucosidase/ phenylacetate- 2-oxoacid:ferredoxin D-altronate class II Camphene 1,2,3 alpha-1,2-1,2,3 sarcosine gamma- asp IMP ribonucleoside- 5-(carboxyamino)imidazole proline-- OHCU alpha-galactosidase: IMP adenine murA CHC09_RS11160 gluconate 3- mycothiol thioesterase: thioesterase: dioxygenase: FMN reductase: mannosidase: dehydrogenase: glutamyltransferase: -CoA ligase: oxidoreductase diphosphate reductase tRNA ligase: fumarate synthase: decarboxylase: CHC09_RS14790 a sugar RS06485 a sugar ribonucleotide synthase: UDP-N-acetylglucosamine altronate chorismate dehydrogenase: dehydrogenase: CHC09_RS30345 CHC09_RS23415 CHC09_RS19350 CHC09_RS28640 CHC09_RS39160 CHC09_RS15635 subunit beta: subunit alpha: CDP purine-nucleoside CHC09_RS11710 hydratase: CHC09_RS06570 (2Z,4E)-2- Man GlcNAc CHC09_RS00585 an αCHC09_RS29385-(5-L- superpathway of pyrimidine deoxyribonucleoside salvage CHC09_RS11645 1-carboxyvinyltransferase: dehydratase: uraD mutase: aroH CHC09_RS06025 CHC09_RS24395 [+ 4 isozymes] [+ 4 isozymes] [+ 9 isozymes] β-D- 5 2 a 5,10- [+ 2 isozymes] CHC09_RS05125 adenylosuccinate IMP dehydrogenase: CHC09_RS09780 phosphorylase: deoD aspA sulfite hydroxyhexa- -[protein] gly a peptide glutamyl)- a reduced ribonucleoside- N5-CAIR proline-- CHC09_RS14535 (-)-camphene 3-dehydro-2- a long-chain (+)-7-epi- + mannopyranose methenyltetrahydrofolate diphosphate AMP phenylacetyl-CoA synthase: CHC09_RS11065 pro Polymeric Compound Degradation murA fumarate (S)-(+)-allantoin prephenate S-formylbacillithiol 2,4-dienedioate H NADH FMN (isomer 5A ) amino acid D-glucopyranose maltotetraose H + ferredoxin [iron- CO an acyl-CoA ribonucleoside- diphosphate reductase 2'-deoxycytidine adenosine tRNA ligase: 2-dehydro- deoxy-D-gluconate fatty acid jasmonate 1,2 2 CHC09_RS37355 [+ 2 isozymes] UDP-N-acetyl-α- sulfur] cluster a cation RS16745 a cation diphosphate reductase: subunit alpha: 5-(carboxyamino)imidazole CHC09_RS02355 an L-prolyl- 3-deoxy-D- adenylosuccinate chitin degradation II (Vibrio) D-glucosamine- CHC09_RS09785 CHC09_RS09780 cytidine deaminase: ribonucleotide mutase: purE adenosine deaminase: [tRNA Pro ] pectin degradation III gluconate synthetase: XMP cellulose and hemicellulose enolpyruvate dUDP CHC09_RS38410 CHC09_RS44185 a tRNA Pro 2-dehydro-3- a 2-O-(α-D-mannosyl)-1- undecaprenyl-diphospho-N [+ 2 isozymes] degradation (cellulolosome) 34 L-gulono- (5Z)- D-firefly CHC09_RS29040 CAIR UDP-N- a cytidine (Z)-hex-3-en-ol a kanamycin H O preuroporphyrinogen a uridine in tRNA a uracil in DNA N-methyl-L- a proteinogenic maltohexaose decanoate γ α cytidine deaminase: dCMP [+ 2 isozymes] chitin deoxygluconokinase: lys L-homoserine dodecenoyl-CoA luciferyl-CoA 2 phosphatidyl-1D-myo-inositol glutathione -acetylmuramoyl-L-alanyl- - UDP-N-acetyl- -D-glucosamine nucleoside dCDP a pectin in tRNA Ile2 1,4-lactone tryptophan amino acid xanthosine-5'- pyrimidine deoxyribonucleotides a (1->4)- acetylenolpyruvoylglucosamine CHC09_RS00065 acyl-CoA CHAT domain- aminoglycoside acyl-CoA uroporphyrinogen- uracil-DNA phosphatidylinositol alpha-glucosidase/ acyl-CoA synthetase: D-glutamyl-L-lysyl- D-alanine a sugar RS09760 a sugar diphosphate kinase: CHC09_RS04705 pectin esterase: tRNA(Ile) gluconolactonase: tRNA dihydrouridine N-methyl-L- gamma- undecaprenyldiphospho- adenylo-succinate phosphate:L- (d)CMP kinase: phosphoribosylaminoimidazolesuccinocarboxamide chitinase: a (1->4)-β-D-xylan β-D-xylan reductase: CHC09_RS35505 cystathionine phosphotransferase: mannoside alpha-galactosidase: nucleoside biosynthesis from CTP inosine CHC09_RS39580 CHC09_RS06595 dehydrogenase: containing protein: thioesterase: III synthase: synthase DusB: glycosylase: tryptophan oxidase: glutamyltransferase: CHC09_RS18570 muramoylpentapeptide beta-N- CHC09_RS23535 CHC09_RS36525 synthase: CHC09_RS22060 CHC09_RS14155 oligosaccharide UDP-N-acetyl- KDGP -lysidine acyltransferase: CHC09_RS14790 adenylosuccinate glutamine amido- diphosphate kinase: 2'-deoxyuridine gluconolactonase: gamma-lyase: CHC09_RS14440 CHC09_RS06555 CHC09_RS13650 CHC09_RS23415 CHC09_RS10885 CHC09_RS10955 [+ 18 isozymes] nucleoside- CTP phenylalanine- [+ 4 isozymes] pectin esterase: α-D-muramate synthetase: CHC09_RS38585 CHC09_RS00580 CHC09_RS29385an α-(γ-L- acetylglucosaminyltransferase: ligase (AMP-forming) CHC09_RS23535 dCDP CHC09_RS02670 [+ 2 isozymes] [+ 8 isozymes] [+ 4 isozymes] [+ 2 isozymes] [+ 3 isozymes] CHC09_RS31615 [+ 2 isozymes] lyase: SAICAR -tRNA ligase CHC09_RS25850 2-dehydro-3- tilS CHC09_RS37710 [+ 36 isozymes] a 5,6-dihydrouridine trp formaldehyde a 2-O-(6-O-acyl-α-D-mannosyl)- L-cysteinyl-glycine glutamyl)-L- ditrans,octacis-undecaprenyldiphospho-murG diphosphate kinase: 34 (2E,5Z)- an apyrimidinic diphosphate decanoyl-CoA CHC09_RS37380 : CHC09_RS11090 nucleoside- thymidine kinase: purine-nucleoside a chitodextrin a lysidine 2-oxobutanoate (3Z)-hex-3- a kanamycin D-firefly luciferin uroporphyrinogen-III uracil D-glucopyranose maltopentaose AMP a sugar RS33025 a sugar CHC09_RS38145 nucleoside subunit beta: a pectate feruloyl esterase: ferulate deoxyphosphogluconate L-gulonate in tRNA 1-phosphatidyl-1D-myo-inositol amino acid UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- diphosphate kinase: CHC09_RS22205 phosphorylase: deoD in tRNA Ile2 dodecenoyl-CoA en-1-yl acetate 3'-phosphate site in DNA diphosphate kinase: adenylosuccinate CHC09_RS31080 a feruloyl- CHC09_RS15860 aldolase: CHC09_RS00070 L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine GMP dUTP CHC09_RS38145 thymidine kinase: CDP UDP-N-acetyl- AMP thymidine CHC09_RS23535 lyase: CHC09_RS37380 superpathway of 5-aminoimidazole phenylalanine- polysaccharide CHC09_RS18840 hypoxanthine a polysaccharide α-D-muramoyl- pyruvate dUTP diphosphatase: dCTP ribonucleoside- ribonucleotide biosynthesis -tRNA ligase nucleoside- phe γ 6-O-cis-keto- a 1-phosphatidyl- a peptide with a [pyruvate a sugar RS30940 a sugar guanylate kinase: CHC09_RS01600 thymidine kinase: AICAR L-alanyl- -D- a pectate wound RNA oleoyl-CoA palmitoleoyl-CoA stearoyl-CoA H O a dipetide with an N- a steryl-ester maltotriose isoprimeverose a 1,4-α-D-glucan linoleate adenylate kinase: diphosphate kinase: diphosphate reductase subunit alpha: a chitodextrin D-galactopyranuronate IPP mycolyl-trehalose 2 dehydrogenase a sulfurated dUMP CHC09_RS22205 glutamyl-meso-2,6- 1D-myo-inositol terminal L-aspartate an N-terminal CHC09_RS31225 PRPP SAM 6 CHC09_RS10750 nucleoside triphosphate CHC09_RS38145 subunit alpha: hypoxanthine CHC09_RS31085 an L-phenylalanyl- isopentenyl- 6-phosphate pectate lyase: RNA helicase: acyl-CoA acyl-CoA acyl-CoA dipeptidase: cholesterol esterase: Xaa-L-proline alpha-glucosidase/ alpha-xylosidase: alpha-glucosidase/ acyl-CoA synthetase: E2 protein] N - [sulfur carrier] thymidine kinase: bifunctional diaminopimelate phosphatidylinositol leucyl predicted pyrophosphohydrolase: CHC09_RS09780 amidophosphoribosyltransferase: Phe a xyloglucan trehalose- CHC09_RS12800 dehydrogenase: CHC09_RS39050 CHC09_RS39620 alpha-galactosidase: CHC09_RS39175 alpha-galactosidase: CHC09_RS36460 octanoyl-L-lysinelipoyl adenylate kinase: thymidylate dCTP phosphoribosylaminoimidazolecarboxamide phosphoribosyltransferase: hpt [tRNA ] a xyloglucan diphosphate CHC09_RS13915 dehydrogenase: thioesterase: kinase: aminopeptidase: CHC09_RS18840 a tRNA Phe cellotetraose hyaluronan degradation phosphatase: CHC09_RS14790 CHC09_RS14790 synthase: ABC CHC09_RS25735 GDP CHC09_RS11370 synthase: [+ 2 isozymes] formyltransferase/IMP cyclohydrolase CHC09_RS37410 Delta-isomerase: [+ 6 isozymes] RNA helicase: CHC09_RS14440 CHC09_RS14440 CHC09_RS30345 [+ 2 isozymes] cholesterol esterase: alpha-xylosidase: [+ 18 isozymes] a sugar a sugar 5-phospho-β- aldehydo-D- CHC09_RS12610 a peptide with CHC09_RS08570 lipA a [pyruvate transporter otsB an unsaturated CHC09_RS26515 [+ 36 isozymes] a 1-phosphatidyl- a proteinogenic CHC09_RS20195 a proteinogenic [+ 2 isozymes] CHC09_RS35930 [+ 2 isozymes] dUMP CHC09_RS01470 dCDP PurH: CHC09_RS11210 D-ribosylamine CHC09_RS37520 [+ 36 isozymes] [+ 4 isozymes] an N-terminal an unsulfurated dehydrogenase of a sugar IMP beta-N- galacturonate trehalose-cis-keto- (2E,9Z)- (2E,9Z)- asp AMP diphosphate linoleoyl-CoA 5'-deoxyadenosine met ADP hyaluronan pectate an unwound RNA stearate 1D-myo-inositol amino acid a sterol a fatty acid amino acid D-glucopyranose maltose α-D-xylopyranose D-glucopyranose D-glucopyranose a 1,4-α-D-glucan 6 thymidylate synthase: phosphoribosylamine- DMAPP mono-mycolate L-proline [sulfur carrier] E2 protein] N FAICAR superpathway of pyrimidine acetylhexosaminidase: glucuronate hyaluronate lyase: oligosaccharide octadecenoyl-CoA hexadecenoyl-CoA 4-phosphate nucleoside ribonucleoside- CHC09_RS01470 xanthine and nucleoside -glycine ligase: isomerase: -lipoyl-L-lysine pyrimidine nucleobases salvage methionine-- CHC09_RS23885 CHC09_RS27025 a sugar RS18025 a sugar diphosphate kinase: diphosphate xanthosine salvage diphosphate kinase: bifunctional CHC09_RS37360 met CHC09_RS18005 3-(4-deoxy-β-D-gluc-4-enuronosyl) ATP ribonucleoside- dTMP ribonucleosides salvage I uracil tRNA ligase: N,N'- [+ 2 isozymes] N,N',N''- CHC09_RS23535 reductase CHC09_RS23535 dCMP phosphoribosylaminoimidazolecarboxamide 6-O-cis-methoxy- 6-phospho CHC09_RS04855 an L-methionyl- diacetylchitobiose triacetylchitotriose -N-acetyl-D-glucosamine a [protein]-L- (5Z)- an (S)-2- an (R)-2- a [2-oxoglutarate- synthase diphosphate nucleoside- subunit alpha: thymidylate kinase: cytidine nucleoside- formyltransferase/IMP cyclohydrolase GAR bifunctional pyr operon D-tagaturonate 5-hydroxy- an aryl sulfate a folate palmitoyl-CoA H O vernolate a colanic acid lipid A-core a penicillin phytenate mycolyl-trehalose ω 2 L-cystathionine D-glucono- dehydrogenase a sulfurated predicted F1 subunit reductase xanthosine dCMP deaminase: transcriptional regulator/uracil [elongator proline ( = 180) tetradecenoyl-CoA halocarboxylate halocarboxylate SAM diphosphate kinase: CHC09_RS09780 CHC09_RS23760 dTMP diphosphate kinase: PurH: CHC09_RS11210 beta-N- L-tryptophan 6 ABC elongator tRNA Met ] 6-phosphate sulfatase: peptidylprolyl acyl-CoA dihydrofolate acyl-CoA HAD family O-antigen 1,5-lactone HAD family penicillin acylase: acyl-CoA synthetase: E2 protein] N - [sulfur carrier] a sugar a sugar epsilon: subunit alpha: cytidine deaminase: CHC09_RS10105 phosphoribosyltransferase: acetylhexosaminidase: epoxide hydrolase: cystathionine CHC09_RS38145 dTMP kinase: purine-nucleoside CHC09_RS38145 tRNA Met 4-deoxy-L-threo-hex- trehalose- aromatic acid CHC09_RS00310 isomerase: dehydrogenase: reductase: thioesterase: hydrolase: ligase domain- hydrolase: CHC09_RS05830 CHC09_RS36460 octanoyl-L-lysinelipoyl transporter atpC CHC09_RS09780 ribonucleoside- thymidylate kinase: N-acetyl-D-glucosamine CHC09_RS38370 gamma-lyase: 6-phosphogluconolactonase: CHC09_RS26910 phosphorylase: CHC09_RS38410 dUMP CHC09_RS31270 CHC09_RS23885 4-enopyranuronate phosphatase: decarboxylase: containing protein: synthase: of a sugar diphosphate CHC09_RS23760 IMP sulfatase: CHC09_RS44385 CHC09_RS14440 CHC09_RS31870 CHC09_RS30345 [+ 2 isozymes] CHC09_RS02670 CHC09_RS36280 pgl CHC09_RS36280 penicillin amidase: [+ 18 isozymes] a [2-oxoglutarate [+ 7 isozymes] ribonucleoside- deoD cytidine deaminase: CMP dCTP uracil [+ 2 isozymes] D-fructuronate otsB CHC09_RS26490 CHC09_RS30640 lipA predicted reductase: dTDP dTMP kinase: thymidylate synthase: FGAR trehalose- CHC09_RS42100 [+ 4 isozymes] [+ 36 isozymes] [+ 4 isozymes] [+ 4 isozymes] (9Z)-12,13- [+ 15 isozymes] [+ 10 isozymes] CHC09_RS01145 an unsulfurated dehydrogenase diphosphate xanthine CHC09_RS04705 phosphoribosyltransferase: N-acetyl-D- a [protein]-L- (2E,5Z)- 2-oxobutanoate cys an (R)-2- D-gluconate an (S)-2- diphosphate AMP phytenoyl-CoA ABC GTP CHC09_RS09785 CHC09_RS01470 serotonin dihydroxyoctadeca- E. coli M 5'-deoxyadenosine met 6 nucleoside CHC09_RS26910 cis-methoxy- a phenol a 7,8-dihydrofolate palmitate a halide anion LPS 6-phosphate a halide anion a carboxylate 6-aminopenicillanate [sulfur carrier] E2 protein] N a sugar a sugar reductase: phosphoribosylformylglycinamidine CHC09_RS04635 lysine- glucosamine proline (ω = 0) tetradecenoyl-CoA 9-enoate hydroxyacid hydroxyarboxylate transporter diphosphate kinase: dTMP adenine and a tRNA Lys mono-mycolate -lipoyl-L-lysine ATP CHC09_RS09785 dTDP uridine synthase subunit PurS: UMP -tRNA of a sugar CHC09_RS23535 adenosine salvage I Inorganic Nutrient Metabolism predicted dGDP nucleoside uridine kinase: guanine and guanosine salvage thymidylate kinase: CHC09_RS37385 (d)CMP kinase: ligase: lysS an L-lysyl- nucleoside- Lys 6-O-trans-keto- 3 ABC diphosphate kinase: CHC09_RS12520 CHC09_RS23760 [+ 2 isozymes] CHC09_RS36525 [tRNA ] a [protein]- a supercoiled (6Z,9Z,12Z,15Z,18Z)- an (R)-2- an N -methyladenine an (S)-2- a sugar a sugar acetyl-CoA cis-vaccenoyl-CoA oleoyl-CoA H O trans-aconitate long chain chitin 4-hydroxyphenylpyruvate pristanate O-acetyl-L- dADP diphosphate kinase: XMP adenosine selenate reduction mycolyl-trehalose duplex DNA 2 halocarboxylate halocarboxylate methanethiol transporter nucleoside CHC09_RS23535 uridine kinase: dTMP kinase: UMP kinase: lys sulfate reduction urea cycle two-component alkanesulfonate monooxygenase L-tyrosine polyphosphate tetracosapentaenoyl-CoA in DNA homoserine CHC09_RS38145 purine-nucleoside FGAM 6-phosphate ATP-dependent acetyl-CoA acyl-CoA acyl-CoA HAD family beta-N- DNA-3- HAD family 4-hydroxyphenylpyruvate acyl-CoA synthetase: of a sugar diphosphate kinase: nucleoside- CHC09_RS05425 guanosine CHC09_RS26910 CHC09_RS02235 III (assimilatory) protein trans-aconitate O-acetylhomoserine phosphorylase: trehalose- DNA helicase: acetyltransferase: dehydrogenase: thioesterase: exopolyphosphatase: acyl-CoA oxidase: hydrolase: acetylhexosaminidase: methyladenine hydrolase: dioxygenase: hppD CHC09_RS18570 nucleoside CHC09_RS23535 dTTP diphosphate kinase: purine-nucleoside dTDP selenate tyrosine kinase: methyltransferase: aminocarboxypropyltransferase/ UMP deoD phosphoribosylformylglycinamidine UDP an alkylsulfonate FMNH phosphatase: CHC09_RS35415 CHC09_RS05940 CHC09_RS14440 CHC09_RS30345 CHC09_RS13405 CHC09_RS19155 CHC09_RS36280 CHC09_RS23885 glycosylase I: CHC09_RS36280 4-hydroxyphenylpyruvate [+ 18 isozymes] diphosphate kinase: CHC09_RS38145 phosphorylase: sulfate sulfate arg ammonium 2 CHC09_RS18710 CHC09_RS31675 cysteine synthase: sulfate RS00780 sulfate nucleoside- cyclo-ligase: CHC09_RS37415 otsB [+ 2 isozymes] CHC09_RS05100 CHC09_RS23535 deoD nucleoside adenine nucleoside diphosphate adenylyltransferase sulfate trehalose- a [protein]- [+ 11 isozymes] [+ 7 isozymes] [+ 36 isozymes] [+ 4 isozymes] (E)-3- (2E,6Z,9Z,12Z,15Z,18Z) [+ 10 isozymes] [+ 10 isozymes] dioxygenase: hppD CHC09_RS34490 diphosphate kinase: histidine-- a single (2E,11Z)- long chain an (R)-2- N-acetyl-D- an apurinic site an (S)-2- AMP diphosphate pristanoyl-CoA dTTP guanine diphosphate kinase: kinase: CHC09_RS23535 his carbamoyl- L-tyrosine acetoacetyl-CoA oleate (methoxycarbonyl) a halide anion chitin 3-methyladenine a halide anion homogentisate nucleoside- CMP phosphorylation AIR tRNA ligase: subunit CysN: adenylyltransferase trans-keto- polyphosphate -tetracosahexaenoyl-CoA glucosamine acetate met CHC09_RS38145 CHC09_RS23535 adenine phosphate stranded DNA octadecenoyl-CoA pent-2-enedioate hydroxyacid within DNA hydroxyarboxylate predicted diphosphate kinase: nucleoside-diphosphate CHC09_RS31520 CHC09_RS04775 subunit CysN: phosphate mono-mycolate CMP phosphoribosyltransferase: an L-histidyl- synthase ABC CHC09_RS38145 nucleoside- kinase: CHC09_RS38145 His CHC09_RS04775 a sugar a sugar dGTP hypoxanthine CHC09_RS31545 [tRNA ] sulfate (d)CMP kinase: His arginase: small subunit: transporter diphosphate kinase: UTP a tRNA adenylyltransferase sulfate CHC09_RS36525 phosphoribosyltransferase: hpt CHC09_RS31255 a [protein]- (7Z)- an insertion sequence 3-oxopentanoyl- of a sugar dATP CHC09_RS38145 subunit CysD: adenylyltransferase CHC09_RS03050 carbonic acid 3-methylcatechol lauroyl-CoA H O NADH maltotetraose a glycogen a dietary all-trans-retinyl ester penicillin G α-linolenate a [formate C CDP AMP argininosuccinate a protein 2 a protein SAM a reduced flavodoxin predicted CTP synthase: NADPH-dependent L-histidine tetradecenoyl-CoA element IS30 CoA acetyltransferase]-glycine dTTP CHC09_RS04780 subunit CysD: lyase: argH carbamoyl- alkanesulfonate carbonic acyl-CoA acyl-CoA NAD(+) acetyl-CoA glycogen/starch/ glycogen/starch/ triacylglycerol lipase: penicillin amidase: acyl-CoA synthetase: ABC nucleoside diphosphate GMP CHC09_RS36360 adenosine 5'- FMN reductase: histidine kinase: catechol 2,3- transposase: Xaa-Pro dipeptidyl- pyruvate a sugar a sugar CHC09_RS04780 L-arginino- phosphate monooxygenase: anhydrase: dehydrogenase: thioesterase: diphosphatase: acetyltransferase: alpha-glucan alpha-glucan CHC09_RS23155 CHC09_RS01145 CHC09_RS36460 transporter kinase: CHC09_RS23535 CTP phosphoselenate L-ornithine CHC09_RS28640 proteasome CHC09_RS23860 dioxygenase: CHC09_RS04660 peptidase: formate-lyase glycine-- APS succinate synthase CHC09_RS41970 CHC09_RS00210 CHC09_RS14440 CHC09_RS30345 CHC09_RS03935 CHC09_RS05940 phosphorylase: phosphorylase: [+ 18 isozymes] of a sugar ATPase: arc [+ 22 isozymes] CHC09_RS19350 [+ 2 isozymes] CHC09_RS34655 triacylglycerol lipase: penicillin acylase: 1-activating nucleoside-diphosphate large [+ 9 isozymes] reduced β- CHC09_RS00715 tRNA ligase: phosphoadenylyl- argininosuccinate a [protein]- [+ 3 isozymes] 2-hydroxy- [+ 36 isozymes] [+ 4 isozymes] an insertion [+ 7 isozymes] CHC09_RS00715 CHC09_RS30610 CHC09_RS05830 enzyme: pflA kinase: CHC09_RS38145 subunit: carB (2E,7Z)- nicotinamide D- AMP a peptide a dipeptide α-D-glucopyranose α-D-glucopyranose AMP diphosphate α-linolenoyl-CoA a [formate C CHC09_RS38565 N-phospho- CO H O 6-oxohepta- laurate sequence IS30 with propanoyl-CoA acetyl-CoA a fatty acid all-trans-retinol phenylacetate 6-aminopenicillanate a flavodoxin sulfate reductase: synthase: argG a peptide 2 2 maltotriose maltotetraose met 5'-deoxyadenosine acetyltransferase]- sulfite RS25415 sulfite L-histidine 2,4-dienoate tetradecenoyl-CoA integrated transposon ribonucleotide 1-phosphate 1-phosphate CTP gly glycine-- selenite CHC09_RS03700 argininosuccinate carbamoyl semiquinone glycin -2-yl radical tRNA ligase: synthase: phosphate sulfate activation CHC09_RS17790 sulfite ornithine Gly CHC09_RS37565 for sulfonation a glycyl-[tRNA ] carbamoyltransferase: a double- 4-trans- 3-[(1- 3S-(4-hydroxyphenyl)-3- 2-carboxymethyl-3- (2E,6Z,9Z,12Z,15Z,18Z) a nascent peptidoglycan with (L- a phosphate DNA with lesion (S)-5-hydroxyisourate a [protein] (L-serine/L- phytosphingosine nigeran maltoheptaose Gly assimilatory sulfite argF cys carboxyvinyl) alanyl-γ-D-glutamyl-meso-2,6- met RS08510 met L-histidine biosynthesis Amino Acid Biosynthesis a tRNA sulfate monoester helix DNA undecenoyl-CoA threonine) phosphate SAM hydroxy-propanoyl-CoA hydroxyphenylpropanoyl-CoA -tetracosahexaenoyl-CoA dGTP superpathway of L-serine L-homoserine reductase (NADPH) mycodextranase: glycogen/starch/ L-lysine biosynthesis I L-arginine biosynthesis II (acetyl cycle) superpathway of L-cysteine L-cysteine biosynthesis selenodiglutathione an aldehyde FMN alkaline DNA helicase: excinuclease protein sphingosine kinase: oxy]benzoateaminofutalosine enoyl-CoA hydratase: enoyl-CoA hydratase: enoyl-CoA hydratase: diaminopimeloyl-D-alanine)LD-carboxypeptidase: tetrapeptide and glycine biosynthesis I biosynthesis : CHC09_RS03705 L-citrulline sulfate cystathionine hydroxyisourate CHC09_RS09645 alpha-glucan deoxyguanosinetriphosphate predicted biosynthesis (mammalian) VI (from L-methionine) phosphatase: CHC09_RS24415 acyl-CoA oxidase: ABC subunit UvrA: phosphatase: CHC09_RS01370 synthase MqnE: CHC09_RS17360 CHC09_RS17360 CHC09_RS17515 CHC09_RS14975 PRPP adenylyltransferase beta-synthase: triphosphohydrolase: ABC CHC09_RS30905 CHC09_RS19155 CHC09_RS13600 hydrolase: uraH sphingosine kinase: mycodextranase: enoyl-CoA hydratase: phosphorylase: enoyl-CoA hydratase: enoyl-CoA hydratase: N-acetylglutamyl- 3-phospho- H O subunit CysN: [+ 4 isozymes] CHC09_RS09185 CHC09_RS26535 CHC09_RS38640 LD-carboxypeptidase: met transporter met asp asp 2 phosphate acquisition CHC09_RS11490 an unwound 2-trans, 4-trans [+ 4 isozymes] (S)-2-oxo-4- CHC09_RS12785 6-amino-6- CHC09_RS00180 CHC09_RS17515 CHC09_RS00715 CHC09_RS17515 CHC09_RS17360 ATP phosphate met met D-glycerate CHC09_RS04775 [+ 3 isozymes] [+ 2 isozymes] met α a nascent peptidoglycanCHC09_RS24965 with of L- phosphoglycerate methionine-- double- -undecadienoyl- DNA without hydroxy-4-carboxy- phytosphingosine deoxyfutalosine nigerosyl-α- -D-glucopyranose (3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z) 2'-deoxyguanosine PPP phosphoribosyltransferase: aspartate kinase: methionine aspartate kinase: met ser an alcohol a [protein] Ser/Thr nigerose 4-coumaroyl-CoA maltohexaose (E)-2-benzylidenesuccinyl-CoA i D-ala (L-alanyl-γ-D-glutamyl-meso- methionine methionine dehydrogenase: tRNA ligase: glutathioselenol taurine degradation IV a phosphate glyphosate degradation II sulfate stranded DNA CoA lesion 5-ureidoimidazoline 1-phosphate (1->4)-D-glucose 1-phosphate -tetracosapentaenoyl-CoA CHC09_RS31115 CHC09_RS21790 adenosyltransferase: CHC09_RS21790 2,6-diaminopimelate) tripeptide CHC09_RS23675 CHC09_RS04855 an L-methionyl- monoester adenylyltransferase adenosyltransferase: CHC09_RS31210 L-aspartyl- bifunctional 1-(5-phospho- L-aspartyl-4-phosphate N-acetyl-gamma- Met subunit CysD: met RS13935 met bifunctional CHC09_RS31210 SAM [+ 2 isozymes] [initiator tRNA ] taurine β-D-ribosyl)-ATP 3-phosphooxypyruvate 4-phosphate Met RNase H/acid glyphosate ornithine glutamyl-phosphate initiator tRNA CHC09_RS04780 (7Z)- (12Z,15Z)-9,10- an N-acetyl-β- taurine dioxygenase: phosphatase: glycine oxidase 4-cis- 3-oxo-2-(cis-2'-pentenyl)- maltopentaose pyruvate phosphoribosyl-ATP aspartate- acetyltransferase/ reductase: SAM APS ala a dipeptide a [protein] Ser/Thr epoxyoctadeca- cys L-homocysteine tributyrin D-hexosaminide isopenicillin N phosphoserine aspartate- CHC09_RS05510 CHC09_RS08955 ThiO: thiO ATP undecenoyl-CoA hexadecenoyl-CoA a malonyl-[acp] cyclopentane-1-octanoyl-CoA a palmitoleoyl-[acp] a malonyl-[acp] diphosphatase: semialdehyde N-acetylglutamate CHC09_RS31015 hydrogen selenide acyl-CoA serine/threonine 12,15-dienoate triacylglycerol lipase: glycogen/starch/ beta-N- penicillin amidase: pyruvate, phosphate acetylglutamate transaminase: semialdehyde taurine dioxygenase: aminomethylphosphonate glyoxylate membrane beta-ketoacyl-[acyl- cystathionine beta-ketoacyl-[acyl- acid phosphatase: adenylyl-sulfate alanine racemase: acyl-CoA oxidase: dehydrogenase: protein kinase: epoxide hydrolase: acyl-CoA oxidase: CHC09_RS30610 alpha-glucan acetylhexosaminidase: a sugar RS00545 a sugar CHC09_RS31120 dehydrogenase: synthase: kinase: argB dehydrogenase: adenylyl cyclase: dipeptidase: carrier-protein] beta-synthase: carrier-protein] CHC09_RS01145 dikinase: ppdK N-acetyl-L- CHC09_RS27205 CHC09_RS25585 CHC09_RS21105 kinase: cysC CHC09_RS31395 CHC09_RS19155 CHC09_RS38370 CHC09_RS19155 CHC09_RS23885 1-(5-phospho-β- CHC09_RS08895 CHC09_RS31010 N-acetyl-L- CHC09_RS08895 CHC09_RS20275 CHC09_RS14440 CHC09_RS35090 triacylglycerol lipase: phosphorylase: penicillin acylase: pyruvate, phosphate glutamate 5- SAH Secondary Metabolite Biosynthesis 2-aminoacetaldehyde phosphate CHC09_RS32115 synthase II: CHC09_RS11490 synthase II: Glu 3-phospho- [+ 3 isozymes] 2-trans, 4-cis- [+ 2 isozymes] 3-oxo-2-(cis-2'-pentenyl) CHC09_RS00715 [+ 2 isozymes] CHC09_RS05830 dikinase: ppdK D-ribosyl)-AMP aspartate- glutamate aspartate- PAPS [+ 4 isozymes] [+ 36 isozymes] a 3- CHC09_RS13890 [+ 35 isozymes] (12Z,15Z)-9,10- L-cystathionine CHC09_RS23155 CHC09_RS13890an (11Z)-3- semialdehyde L-serine a proteinogenic (2E,7Z)- a [protein] (L-serine/L- α-D-glucopyranose an N-acetyl-β- phosphoribosyl- semialdehyde N-acetylornithine semialdehyde undecadienoyl- dihydroxyoctadeca- -cyclopentane-1-(E- butanoate 1,2-dibutyrin maltotetraose an alcohol SAH preQ biosynthesis D-ala cyclic-AMP amino acid oxodocosanoyl- acyl-carrier protein oxooctadec- L-2-aminoadipate 6-aminopenicillanate + 0 myo-inositol CoA hexadecenoyl-CoA threonine) phosphate octa-2-enoyl)-CoA 1-phosphate D-hexosamine diphosphate AMP phosphoenolpyruvate H nitrate RS26035 nitrate AMP dehydrogenase: aminotransferase: dehydrogenase: [acp] 12,15-dienoate 11-enoyl-[acp] cyclohydrolase: CHC09_RS21785 CHC09_RS31000 CHC09_RS21785 biosynthesis bifunctional CHC09_RS07650 adenosylhomocysteinase: D-glucopyranose L-aspartate- ornithine S-ribosyl-L- L-aspartate- GTP 1-(5-phospho-β-D-ribosyl)- CHC09_RS09615 semialdehyde homocysteine ser semialdehyde GTP cyclohydrolase 6-phosphate 6-O-trans- a [lipoyl-carrier (9Z,15Z)-12,13- (1R,6R)-6-hydroxy-2- icosapentaenoyl- a [lysine-biosynthesis-protein ditrans,octacis- nitrate RS32015 nitrate acetyltransferase/ inositol-3- + a nucleoside 3-aci- 5-[(5-phosphoribosylamino) gln 6 NAD 3-methylcatechol enterobactin glycerol a sphingoid base epoxy-octadeca- succinylcyclohexa-2,4- isobutanal γ an acyl-[acyl- superpathway of branched chain amino acid biosynthesis N-acetylglutamate I FolE: phosphate Carboxylate Degradation methoxy-mycolyl- protein] N -[(R) CoA LysW]-C-terminal- -(L-glutamate a malonyl-[acp] a peptidoglycan with undecaprenyldiphospho- methylideneamino]imidazole- 4-hydroxy- ser homoserine propanoyl CoA pyruvate fermentation triphosphate carrier protein] nitropropanoate predicted serine CHC09_RS09895 pyruvate decarboxylation to acetyl CoA trehalose 6- -dihydrolipoyl]- NAD(+) NAD(P)- sphingosine kinase: 9,15-dienoate diene-1-carboxylate acyl-CoA acetaldehyde 5-semialdehyde-2-yl)-L-glutamate nitronate (L-alanyl-γ-D-glutamyl- N-acetyl-(N-acetyl-β-D- 4-carboxamide tetrahydrodipicolinate synthase: L-homocysteine dehydrogenase: synthase: degradation I catechol 2,3- enterochelin nucleoside triphosphate N-acetyl-gamma- beta-ketoacyl-[acyl- ABC carbamoyl- hydroxymethyltransferase: to acetate IV phosphate L-lysine diphosphatase: dependent alcohol CHC09_RS12785 epoxide hydrolase: thioesterase: dehydrogenase monooxygenase: L-lysyl-D-alanyl-D- glucosaminyl)muramoyl- synthase: dapA pyruvate CHC09_RS31010 N-acetyl-L- CHC09_RS03355 GTP CHC09_RS14460 pyruvate 3-oxoadipate trehalose- dihydrolipoyl dioxygenase: esterase: o-succinylbenzoate pyrophosphohydrolase: glutamyl-phosphate carrier-protein] a branched- transporter a branched- bifunctional 1-(5- thr phosphate CHC09_RS03245 CHC09_RS03935 dehydrogenase: CHC09_RS38370 CHC09_RS23415 (acetylating): CHC09_RS15780 γ glycine glycine cyclohydrolase propanoyl-CoA dehydrogenase CHC09_RS19350 CHC09_RS00640 sphingosine kinase: synthase: menC reductase: synthase II: alanine) pentapeptide L-alanyl-peptidoglycan-D-glutamyl-L- RS21525 phosphoribosyl)-5-((5- 4-hydroxy- synthase ornithine L-homocysteine inositol-3- pyruvate a [pyruvate dehydrogenase degradation phosphatase: dehydrogenase: CHC09_RS34685 [+ 2 isozymes] CHC09_RS11370 chain of a chain betaine betaine acetolactate cystathionine serine L-homoserine 7,8- propionyl-CoA cis,cis-2-hydroxy- N-(2,3- CHC09_RS01370 (9Z,15Z)-12,13- [+ 4 isozymes] CHC09_RS16910 CHC09_RS31015 CHC09_RS13890 [+ 2 isozymes] lysyl-D-alanyl-D-alanineglycosyltransferase: tetrahydrodipicolinate I FolE: folE phosphate 6 (acetyl-transferring) otsB lpdA a [lysine-biosynthesis-protein [unspecified a peptidoglycan with amino acid branched- amino acid phosphoribosylamino) threonine large E2 protein] N -lipoyl-L-lysine trehalose- a [lipoyl-carrier NMN AMP a sphingoid a nucleoside 5'- + synthase beta-synthase: hydroxymethyltransferase: dihydroneopterin carboxylase 6-oxohepta- dihydroxybenzoyl) [+ 2 isozymes] dihydroxyoctadeca- 2-succinylbenzoate coenzyme A icosapentaenoate H NADH isobutanoyl-CoA γ CHC09_RS37030di-trans,octa-cis synthase: cystathionine synthase: E1 component 3-oxoadipate 6 LysW]-C-terminal- -(5-phospho- acyl-carrier protein a 3-oxoacyl-[acp] degradation nitrite 3-oxopropanoate (L-alanyl-γ-D-glutamyl- chain methylideneamino)imidazole- ammonia-lyase: subunit: carB 3'-triphosphate trans-methoxy- protein]-N - 2,4-dienoate -L-serine 1-phosphate monophosphate -undecaprenyl CHC09_RS24820 small subunit: CHC09_RS11490 beta-synthase: CHC09_RS09555 subunit beta: formate C- subunit alpha: pdhA 3-oxoadipate L-glyceraldehyde 9,15-dienoate L-glutamyl)-L-glutamate products] L-lysyl-D-alanyl-D- predictedamino acid ABC 4- carboxamide isomerase/ CHC09_RS11600 CHC09_RS23030 mono-mycolate lipoyl-L-lysine diphosphate (2S,4S)-4- CHC09_RS02850 carbamoyl- CHC09_RS11490 6-carboxytetrahydropterin CHC09_RS09080 acetyltransferase: pyruvate CoA-transferase: alanine) pentapeptide a carbohydrate transporter of a carbohydrate hemin RS21130 hemin phosphoribosylanthranilate [+ 2 isozymes] Ins(3)P dihydrolipoyl pyruvate hydroxy-2,3,4,5- [+ 2 isozymes] phosphate gly synthase: pflB CHC09_RS34795 isomerase PriA: [+ 4 isozymes] dehydrogenase a carbohydrate tetrahydrodipicolinate (2Z)-2-aminobut- synthase L-tryptophan biosynthesis L-cystathionine L-cystathionine CHC09_RS19765 (S)-methylmalonyl- dehydrogenase: lpdA CHC09_RS07725 inositol (acetyl-transferring) 3-oxoadipate 966 (9Z,12Z)-15,16- (S)-2-acetolactate 2-enoate small subunit: 6-carboxy-5,6,7,8- CoA (S)-4-amino-5- 1-myristoylglycerol a guanine 3-oxo-2-(cis-2'-pentenyl)- keto- 4-hydroxy- monophosphatase: acetyl-CoA formate CoA-transferase: digallate (S)-dihydroorotate (2S)-ethylmalonyl-CoA a maltodextrin a (3Z)-dodec- a malonyl-[acp] O-acetyl-L-serine hydrogen selenide predicted ABC glycine glycine CHC09_RS31255 L-arginine methylmalonyl- E1 component oxopentanoate ethylphosphate ala in 16S rRNA epoxyoctadeca- cyclopentane-1-butanoyl-CoA phenylpyruvate a malonyl-[acp] a malonyl-[acp] a palmitoyl-[acp] a malonyl-[acp] RS00600 phosphoribulosylformimino- tetrahydrodipicolinate ketol-acid tetrahydropterin CHC09_RS34800 3-phosphate 3-enoyl-[acp] methyl ester a carbohydrate transporter of a carbohydrate gln chorismate cystathionine degradation VI CHC09_RS10220 subunit alpha: tannase/feruloyl glutamate-1- 16S rRNA 9,12-dienoate methylmalonyl-CoA 4-hydroxyphenylpyruvate glycogen/starch/ O-acetylhomoserine betaine betaine AICAR-phosphate reductase: L-proline biosynthesis III CoA phosphate alkaline pyridoxal phosphate- 1-acyl-sn-glycerol- epoxide hydrolase: beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- reductoisomerase: carbamoyl L-ornithine 7-carboxy-7- CHC09_RS34560 3-oxoadipyl-CoA esterase family dihydroorotase: (guanine(966)-N(2) epimerase: mce acyl-CoA oxidase: dioxygenase: hppD alpha-glucan aminocarboxypropyltransferase/ a carbohydrate gamma-lyase: (arginase 2 pathway) [+ 3 isozymes] epimerase: mce acetyltransferase: semialdehyde- phosphatase: dependent 3-phosphate carrier-protein] carrier-protein] carrier-protein] CHC09_RS01970 CHC09_RS02845 phosphate anthranilate synthase: deazaguanine a [pyruvate dehydrogenase CHC09_RS31260 CHC09_RS38370 CHC09_RS19155 phosphorylase: 2-iminobutanoate CHC09_RS02670 β-ketoadipyl- alpha/beta 2,1- CHC09_RS29710 acyltransferase: )-methyltransferase methylmalonyl-CoA 4-hydroxyphenylpyruvate synthase II: synthase II: synthase II: cysteine synthase: (2R)-2,3- synthase: myo-inositol methylmalonyl- CHC09_RS03640 a [pyruvate dehydrogenase E2 6 superpathway of acetate aminotransferase: imidazole (S)-2,3,4,5- CHC09_RS07645 cys Glu arg E2 protein] N -S- hydrolase: aminomutase: RsmD: rsmD [+ 2 isozymes] epimerase: mce 3-oxo-2-(cis-2'-pentenyl) dioxygenase: hppD CHC09_RS00715 CHC09_RS34490 CoA 6 lipoate CoA thiolase: [+ 5 isozymes] CHC09_RS28875 N-carbamoyl- CHC09_RS25115 an N 2 - (9Z,12Z)-15,16- CHC09_RS13890 CHC09_RS13890 CHC09_RS13890 hemin RS27975 hemin glycerol tetrahydrodipicolinate dihydroxy-3- CHC09_RS09890 protein] N -dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine utilization and formation (2-hydroxyphenyl) α-D-glucopyranose a (5Z)-3-oxo- a carbohydrate RS15310 a carbohydrate (2Z)-2-aminobut- arginase: CHC09_RS15125 hemL 966 dihydroxyoctadeca- (2R)-ethylmalonyl-CoA -cyclopentane-1-(E- a maltodextrin a 3-oxoglutaryl- a 3-oxooctadecanoyl- cysteine synthase B: cysM phosphate methylbutanoate epimerase: mce acetyl phosphate acetyltransferase: CHC09_RS34790 ethanol pyruvate L-aspartate [+ 6 isozymes] methylguanine acetate 1-phosphate acyl-carrier protein tetradec-5- acyl-carrier protein acyl-carrier protein 2,3,4,5- anthranilate 2-enoate cys 7-carboxy-7- 5-aminolevulinate dimyristoyl 9,12-dienoate buta-2-enoyl)-CoA [acp] methyl ester [acp] dihydroxy-acid glutamate 5-kinase: CHC09_RS03050 (R)-methylmalonyl- sucB acetate gallate in 16S rRNA enoyl-[acp] acetate L-selenocysteine synthase tetrahydropyridine- deazaguanine succinyl-CoA acetate--CoA phosphatidate a cation a cation anthranilate CHC09_RS10355 L-ornithine acetate kinase: subunit 2,6-dicarboxylate N- dehydratase: ornithine CoA 2-oxobutanoate CHC09_RS03645 ligase: acs RS22675 HisH: hisH CHC09_RS37715 carbamoyltransferase: phosphoribosyltransferase: trpD γ-L-glutamyl methylmalonyl- acetate kinase: succinyltransferase: ornithine- argF anthranilate CHC09_RS03645 a [2-oxoglutarate acetate acetate imidazole glycerol dapD 3-methyl-2- acetolactate 5-phosphate CoA mutase: citrate degradation (3R,5S)-3- 3-oxo-2-(cis-2'-pentenyl)- methyl-esterified a single a single phosphoribosyltransferase: trpD 2-iminobutanoate glutamate-5- -oxo-acid acetate acetyl-CoA phytol [DNA] sphingosine N-formimino- lanosteryl oleate a (5Z)-tetradec- a glutaryl-[acp] (1S,2R)-1-C-(indol-3- phosphate oxobutanoate synthase preQ CHC09_RS11185 hydroxy-1- Ins(1)P dehydrogenase E2 protein] homogalacturonan stranded DNA a malonyl-[acp] a malonyl-[acp] ser a cation a cation N-succinyl-2-amino- semialdehyde transaminase: 0 IDP cyclopentane-1-hexanoyl-CoA yl)glycerol 3-phosphate stranded DNA small subunit: acetyl phosphate acetyl-CoA bifunctional 3'- sphingosine kinase: L-glutamate N 6 -dihydrolipoyl-L-lysine cholesterol esterase: pectin esterase: endonuclease IV: 5-enoyl-[acp] methyl ester synthase 6-ketopimelate N-(5-phosphoribosyl)-anthranilate rocD [+ 4 isozymes] an acetyl-holo pyrroline-5- NAD(P)- inositol beta-ketoacyl-[acyl- beta-ketoacyl-[acyl- tryptophan synthase exodeoxyribonuclease RS22710 dehydrogenase: D-gluconate nucleoside diphosphate formimidoylglutamate dihydrolipoyl acyl-CoA oxidase: CHC09_RS39580 subunit HisF: 2-isopropylmalate branched-chain CHC09_RS02850 [citrate lyase acyl- citrate carboxylatepyrroline-5- dependent alcohol monophosphatase: 5' exonuclease/ CHC09_RS01370 CHC09_RS20195 CHC09_RS08160 carrier-protein] carrier-protein] subunit beta: trpB VII large subunit: succinyldiaminopimelate L-ornithine CHC09_RS10350 L-glutamate-5- succinyl-CoA degradation DNA polymerase: kinase: CHC09_RS23535 deiminase: dehydrogenase: CHC09_RS19155 acetate acetate CHC09_RS07715 synthase: amino acid [+ 2 isozymes] bifunctional 1-(5- L-isoleucine glycine biosynthesis II carrier protein] carboxylate dehydrogenase: CHC09_RS10220 sphingosine kinase: cholesterol esterase: pectin esterase: deoxyribonuclease synthase II: synthase II: tryptophan synthase CHC09_RS04375 transaminase: dapC CHC09_RS43760 ornithine- glutamate-5- semialdehyde a citryl-holo CHC09_RS06925 nucleoside-diphosphate CHC09_RS24290 lpdA CHC09_RS25850 aminotransferase: (S)-2-aceto-2- phosphoribosyl)-5-((5- ammonium biosynthesis IV phosphate reductase: CHC09_RS34685 [+ 3 isozymes] CHC09_RS12785 a [2-oxoglutarate CHC09_RS39620 3-oxo-2-(cis-2'-pentenyl) IV: CHC09_RS22995 CHC09_RS13890 CHC09_RS13890 subunit beta: trpB exodeoxyribonuclease L-citrulline -oxo-acid semialdehyde D-gluconate [citrate lyase acyl- a nucleoside 5'- kinase: CHC09_RS38145 a (7Z)-3-oxo- D-erythro- N-succinyl-L,L-2,6- 2-isopropylmalate CHC09_RS02825 hydroxybutanoate phosphoribosylamino) a [glycine-cleavage acetyltransferase: proC [+ 2 isozymes] sphingosine N-formyl- dehydrogenase E2 oleate lanosterol -cyclopentane-1-(E- MeOH a homogalacturonan a 5'-phosphooligonucleotide a 3-oxopimeloyl- VII small subunit: nitrate RS41850 nitrate AICAR transaminase: dehydrogenase: gluconate kinase: trans-4-hydroxy- myo-inositol monophosphate acyl-carrier protein hexadec-7- acyl-carrier protein D-glyceraldehyde 3-phosphate trp imidazole-glycerol- diaminopimelate carrier protein] CHC09_RS03640 1-phosphate ITP L-glutamate 6 hexa-2-enoyl)-CoA [acp] methyl ester synthase: leuA ketol-acid methylideneamino)imidazole- propanoate gly complex H protein] phytenal protein] N -lipoyl-L-lysine enoyl-[acp] CHC09_RS04380 argininosuccinate rocD CHC09_RS37635 6 CHC09_RS06915 L-proline phosphate succinyl- reductoisomerase: 4- carboxamide isomerase/ propionyl-CoA N -lipoyl-L-lysineglycine D-gluconate citryl-CoA lyase: a single-stranded a ribonucleoside val synthase: argG (S)-1-pyrroline- imidazoleglycerol- diaminopimelate (2S)-2- CHC09_RS02845 phosphoribosylanthranilate synthetase: dehydrogenase 6-phosphate CHC09_RS27805 oligodeoxyribonucleotide 5'-monophosphate phosphate argininosuccinate 5-carboxylate desuccinylase: isopropylmalate (R)-2,3-dihydroxy- isomerase PriA: prpE (aminomethyl- Peptide RS39815 Peptide dehydratase: synthase: pyrroline-5- oxaloacetate CHC09_RS30965 3-isopropylmalate 3-methylpentanoate CHC09_RS07725 propanoyl-CoA transferring): gcvP CHC09_RS07740 CHC09_RS37565 L-glutamate-5- carboxylate CO a [protein]-L- D-erythro- a cytidine 1402 adenosylcobinamide- UDP-N-acetylmuramoyl-L- a ring-opened 7- dehydratase 2 1-palmitoylglycerol L-arabinitol a (7Z)-hexadec- α predicted succinyl- dihydroxy-acid 1-(o-carboxyphenylamino)-1'- roseoflavin butan-1-ol Ins(2)P ergosteryl oleate a purine 2'- futalosine 3-hydroxyisovaleryl-CoA a malonyl-[acp] -ribazole alanyl-γ-D-glutamyl-meso-2,6- small subunit: leuD L-arginino- 2-oxoacid:ferredoxin semialdehyde L-proline biosynthesis I reductase: Degradation/Utilization/Assimilation - Other methionine sphinganine 3-phosphate in 16S rRNA GDP methylguanine in DNA imidazole acetol- diaminopimelate deoxyribulose 5'-phosphate Aromatic Compound Degradation bifunctional NAD(P)- NAD(P)- deoxyribonucleoside enoyl-CoA hydratase: 7-enoyl-[acp] adenosylcobinamide- diaminopimeloyl-D-alanine bifunctional DNA- ABC efflux dehydratase: succinate oxidoreductase proC inositol peptide-methionine sphingosine kinase: 1-acyl-sn-glycerol- 16S rRNA cholesterol esterase: futalosine beta-ketoacyl-[acyl- LD-carboxypeptidase: thiol transporter thiol phosphate desuccinylase: 3-isopropylmalate CHC09_RS37715 indole-3-glycerol- riboflavin dependent alcohol (S)-S-oxide CHC09_RS01370 dependent alcohol (cytidine(1402)-2'-O) CHC09_RS20195 purine-nucleoside hydrolase: CHC09_RS17360 GDP formamidopyrimidine subunit beta: octane oxidation monophosphatase: 3-phosphate carrier-protein] CHC09_RS14975 CHC09_RS04010 dehydratase argininosuccinate Glu kinase/FAD dehydrogenase: dehydrogenase: phosphorylase: glycosylase/ of a thiol histidinol- (S)-3-methyl-2- phosphate synthase: CHC09_RS05125 pro acrylonitrile syringate degradation CHC09_RS10220 reductase MsrA: sphingosine kinase: acyltransferase: -methyltransferase: cholesterol esterase: CHC09_RS27155 enoyl-CoA hydratase: synthase II: ribazoletransferase: LD-carboxypeptidase: group phosphate large subunit: leuC lyase: argH CHC09_RS07630 degradation I 3,4,6-trichlorocatechol protocatechuate degradation gentisate degradation I phenylethylamine synthetase: CHC09_RS34685 CHC09_RS11580 CHC09_RS34685 rsmI 2-deoxy-α- deoD CHC09_RS08560 DNA-(apurinic or oxopentanoate (S)-1-pyrroline- glutamate 5-kinase: [+ 3 isozymes] a protein-L- CHC09_RS12785 CHC09_RS25115 a 2'-O- CHC09_RS39620 dehypoxanthine CHC09_RS17515 CHC09_RS13890 α CHC09_RS24965 predicted L,L-diaminopimelate 2-oxobutanoate NADH degradation II (ortho-cleavage pathway) degradation I ribF D-ribose 1- a purine base hypoxanthine a (9Z)-3-oxo- UDP-N-acetyl- -D-muramoyl- transaminase: sphinganine [+ 2 isozymes] 1402 (E)-2-methylcrotonoyl-CoA apyrimidinic site) lyase: ABC 2-isopropylmaleate branched-chain (1S,2R)-1-C-(indol-3- 5-carboxylate CHC09_RS10355 [+ 2 isozymes] myo-inositol methionine- 1-palmitoyl-[+ 6 isozymes] methylcytidine oleate ergosterol futalosine acyl-carrier protein octadec-9- L-alanyl-γ-D-glutamyl- D-ala hisC γ-L-glutamyl syringate roseoflavin 1-phosphate phosphate GMP adenosylcobalamin CHC09_RS02510 a sugar a sugar amino acid arg yl)glycerol 3-phosphate acrylonitrile gentisate butan-1-al (S)-S-oxide L-arabinopyranose in 16S rRNA transporter diaminopimelate acetolactate pyrroline-5- 5-phosphate 3,4,6-trichlorocatechol protocatechuate 2-phenylethylamine 2-myristoyl enoyl-[acp] meso-2,6-diaminopimelate 2,6-diamino-4- histidinol- 3-isopropylmalate Fatty Acid and Lipid Biosynthesis 5'-phosphate an apurinic site of a sugar epimerase: aminotransferase: tryptophan synthase synthase carboxylate protocatechuate primary-amine phosphatidate hydroxy-5-(N-methyl) phosphate dehydratase glutamate-5- a reduced within DNA predicted CHC09_RS01760 CHC09_RS02825 subunit alpha: small subunit: reductase: n-octane 3,4-dioxygenase oxidase: formamidopyrimidine transaminase: small subunit: leuD semialdehyde L-arginine rubredoxin acrylamide ABC CHC09_RS07620 CHC09_RS02850 proC palmitate biosynthesis II (bacteria and plants) 2,3,5-trichloro- subunit 3-maleylpyruvate CHC09_RS14010 a sugar a sugar CHC09_RS07745 dehydrogenase: degradation I palmitoleate long-chain fatty 3-O-methylgallate transporter meso-diaminopimelate 3-isopropylmalate ile alkane 1- cis,cis-muconate alpha: pcaG phenylacetaldehyde L-methionine biosynthesis III [+ 3 isozymes] [+ 2 isozymes] CHC09_RS10350 (arginase pathway) biosynthesis I (from maleylpyruvate a [protein]-L- a [protein]-L- 3-carboxy- an [RNA]-3'- a 2'- ditrans,octacis- N-acetyl-D-glucosaminyl-N- a [2-oxoglutarate dehydrogenase E2 of a sugar L-histidinol- dehydratase pro acid activation monooxygenase: amidase: butan-1-ol 1-palmitoylglycerol an (L-cysteinylglycine) 5'-chloro-5'- a nucleoside a (3Z)-dec- (S)-2-aceto-2- β deoxyribonucleoside a purine a ribonucleic acid acetylmuramoyl-L-alanyl-D-glutamyl- 6 diaminopimelate ser an acetoacetyl-[acp] (5Z)-dodec-5-enoate) CHC09_RS11595 protocatechuate isomerase phenylacetaldehyde methionine -alanine β-isoaspartate 2,5-dihydro- ribunucleoside- -S-conjugate deoxyadenosine [DNA] a malonyl-[acp] undecaprenyldiphospho- protein] N -dihydrolipoyl-L-lysine predicted phosphate large subunit: leuC indole glutamate-5- a long-chain CHC09_RS14325 3-phosphate ribonucleoside triphosphate 3-enoyl-[acp] hydroxybutanoate arg 3,4-dioxygenase family mycothiol- peptide- NAD(P)- protein-L- 5-oxofuran- 2',3'- aminopeptidase purine-nucleoside 5'-triphosphate DNA polymerase DNA-directed RNA N-acetyl-(N- 6-carboxy-L-lysyl-D-alanineLD-carboxypeptidase: multifunctional oxoglutarate ABC decarboxylase: lysA (2R,3S)-3- semialdehyde a (5Z)-dodec- fatty acid dehydrogenase: 4-aminobutyrate- 1-acyl-sn-glycerol- purine-nucleoside beta-ketoacyl-[acyl- a sugar a sugar L-homoserine 3-oxoacyl-ACP acrylate 2-chloro-2-(2,4- subunit beta: pcaH methionine dependent alcohol isoaspartate O- 2-acetate cyclophosphate N: pepN phosphorylase: decarboxylase/oxoglutarate histidinol diaminopimelate 2-aceto-2-hydroxy- dehydrogenase: arginase: 5-enoyl-[acp] acyl-CoA 1-octanol dependent enzyme: CHC09_RS04645 -2-oxoglutarate 3-carboxymuconate 3-phosphate RNA 2',3'-cyclic III subunit beta: polymerase II: carrier-protein] acetylglucosaminyl) CHC09_RS14975 transporter isopropylmalate homoserine O- beta-ketoacyl-[acyl- 4-carboxy- dichloro-5-oxofuran- 3-carboxy-cis deoD phosphorylase: phosphate tryptophan synthase butanoate CHC09_RS03050 reductase: fabG synthetase: 2-pyrone-4,6- CHC09_RS35500 (R)-S-oxide dehydrogenase: transaminase: methyltransferase: acyltransferase: aminopeptidase CHC09_RS43320 CHC09_RS23310 synthase II: muramoyl-L-alanyl-γ-D- LD-carboxypeptidase: dehydrogenase thiamine of a sugar decarboxylase: 3-isopropylmalate acetyltransferase: CHC09_RS37635 carrier-protein] 2-hydroxy- gallate 2-yl)acetate ,cis-muconate cyclase: phosphodiesterase: 5-chloro-5- deoD phosphatase: subunit beta: trpB isomeroreductase: [+ 9 isozymes] CHC09_RS36460 dicarboxylate [+ 7 isozymes] phenylacetate reductase: CHC09_RS34685 gabT a protein L-βCHC09_RS20985- CHC09_RS25115 N: pepN [+ 10 isozymes] α-D-ribose- [+ 5 isozymes] CHC09_RS13890 isoglutaminyl-L-lysyl-peptidoglycan CHC09_RS24965 pyrophosphate-binding CHC09_RS39570 dehydrogenase: CHC09_RS34495 L-glutamate-5- L-ornithine synthase II: 6-methoxy- 3-carboxy- CHC09_RS23825 an [RNA]-3'-CHC09_RS27195 adenine deoxyribose a purine base a (5Z)-3- N-acetyl-D-glucosaminyl-N- CHC09_RS12860 tryptophan synthase CHC09_RS02845 [+ 18 isozymes] msrB [+ 2 isozymes] 3-carboxy-cis an L-cysteine- 1-phosphate (glycyl) -D-alanyl-D-alanine subunit/dihydrolipoyllysine- hydrogen sulfide O-acetyl-L-homoserine a (3R)-3- a (7Z)-3- a long-chain cis,cis-muconate a protein-L- 3-oxopropanoate isoaspartate 1-palmitoyl-2-[+ 6 isozymes] gly [DNA] a ribonucleic acid acyl-carrier protein oxododec- 5 di-trans,octa-cisglycosyltransferase: D-ala acetylmuramoyl-L-alanyl-D- lys RS07210 lys CHC09_RS02830 semialdehyde CHC09_RS13890 6-oxohexa- gala protein: 3-fumarylpyruvate ,cis-muconate ribunucleoside- S-conjugate 1-phosphate a peptidoglycan residue succinyltransferase [+ 2 isozymes] lys subunit beta: trpB (R)-2,3-dihydroxy- ornithine- hydroxybutanoyl-[acp] acyl-CoA methionine- butan-1-al α-methyl ester cis-vaccenoyl 5-enoyl-[acp] -undecaprenylCHC09_RS37030 glutamyl-6-carboxy-L-lysine (2S)-2-isopropyl- oxotetradec- 1-octanal 2,4-dienoate CHC09_RS29880 cycloisomerase: 2'-phosphate dimer (S. aureus) subunit: CHC09_RS03630 3-methylpentanoate -oxo-acid 2,5-dichloro-trans (R)-S-oxide histidinol 3-oxosuccinate O-acetylhomoserine (3R)-3- 7-enoyl-[acp] CHC09_RS31925 phosphatidate diphosphate a [2-oxoglutarate dehydrogenase E2 transaminase: predicted aminocarboxypropyltransferase/ dihydroxy-acid 3-oxoacyl-ACP 4-trimethylaminobutyraldehyde -dienelactone (2-carboxy- 6 trp hydroxybutanoyl- (1E)-4-oxobut- protein] N -S-succinyldihydrolipoyl-L-lysine ABC histidinol dehydratase: rocD dehydrogenase: 2,5-dihydro- cysteine synthase: (S)-1-pyrroline- [acyl-carrier protein] reductase FabG: 1-ene-1,2,4- fumarate pyruvate a sugar a sugar CHC09_RS37715 (1Z,3Z)-4- transporter dehydrogenase: CHC09_RS34490 5-carboxylate L-glutamate-5- dehydratase: CHC09_RS36490 CHC09_RS04645 tricarboxylate 5-oxofuran- of a sugar hisD superpathway of L- 4-methyl-2- (S)-3-methyl-2- semialdehyde [+ 9 isozymes] hydroxybuta- 2-yl)-acetate a (9Z)-3-oxo- a [release factor]- 4-hydroxy-2- a [protein]- cyclic a (2'R)-2'- undecaprenyl- pyrroline-5- CHC09_RS13890 4-oxalomesaconate cerotoyl-CoA 1-palmitoylglycerol FAD a (4Z)-hexadec- 1-palmitoylglycerol a 1-phosphatidyl- predicted asparagine biosynthesis L-homocysteine a (3R,7Z)-3- octanoate 1,3-diene-1,2,4- 5-MTR-1-P thr octadec-9- a decanoyl-[acp] L-glutamine nonenal-[Cys- dehypoxanthine a purine a malonyl-[acp] a palmitoyl-[acp] hydroxy- diphospho-N- oxopentanoate oxopentanoate tautomerase: 2,5-dichloromaleylacetate 4-carboxymuconolactone 3-phosphate L-threonine oxaloacetate ITP arsenate 4-enoyl-[acp] 3-phosphate 1D-myo-inositol histidinal carboxylate 1-pyrroline-5- tricarboxylate propionyl-CoA enoyl-[acp] peptide chain Gly] conjugate FAD:protein FMN futalosine ribonucleoside phytoceramide acetylmuramoyl- UDP-N-acetyl- ABC branched-chain branched-chain a (2E)-but-2-enoyl-[acp] hydroxytetradec- decarboxylase: pcaC S-methyl-5- threonine 3-oxoacyl-ACP 1-acyl-sn-glycerol- aminopeptidase 1,4-dihydroxy- beta-ketoacyl-[acyl- 1-acyl-sn-glycerol- inositol a sugar a sugar 5-methyltetrahydropteroyltriglutamate- methionine synthase: reductase: carboxylate acyl-CoA CHC09_RS19345 phosphoenolpyruvate purine-nucleoside γ α transporter asp 7-enoyl-[acp] maleylacetate thioribose-1- carboxylase reductase FabG: acyl-CoA oxidase: 3-phosphate release factor N: pepN transferase: carrier-protein] 3-phosphate phosphorylceramide L-alanyl- -D- -D-glucosamine histidinol amino acid amino acid proC dehydrogenase: synthetase: carboxymuconolactone resorcinol degradation ammonia-lyase: 6-naphthoate carboxykinase (GTP) phosphorylase: of a sugar - homocysteine S-methyltransferase: CHC09_RS06920 reductase: phosphate subunit beta: N(5)-glutamine CHC09_RS01085 acyltransferase: glutamyl-L-lysyl- undecaprenyldiphospho- dehydrogenase: aminotransferase: aminotransferase: crotonyl-[acyl- CHC09_RS18570 decarboxylase: CHC09_RS11600 CHC09_RS36490 CHC09_RS19155 acyltransferase: aminopeptidase synthase: : CHC09_RS04425 synthase II: synthase: CHC09_RS12950 methionine synthase: CHC09_RS18445 CHC09_RS43930 CHC09_RS09080 methyltransferase: deoD D-alanyl-D-alanine muramoylpentapeptide beta-N- hisD CHC09_RS02825 CHC09_RS02825 carrier-protein] CHC09_RS12995 isomerase: [+ 9 isozymes] CHC09_RS25115 N: pepN a [protein]-FMN- CHC09_RS27125 phosphoenol CHC09_RS13890 CHC09_RS31170 CHC09_RS01975 pro fatty acid elongation -- saturated [+ 18 isozymes] resorcinol [+ 2 isozymes] a (3R,9Z)-3- a (2E)-dec- 4-hydroxy-2- AMP IDP ribose-1-arsenate a purine base a (6Z)-3- ditrans,octacisacetylglucosaminyltransferase:- asparagine asparagine [+ 2 isozymes] CHC09_RS02950 2,5-dichloro-3- (4,5-dihydro- mtnA [+ 4 isozymes] prmC L-threonine an unknown 1,4-dihydroxy- pyruvate Peptide RS21830 Peptide Glu reductase: 5-(methylthio) 2-oxobutanoate hydroxy-octadec- 1-palmitoyl-2-[+ 6 isozymes] 5 gly nonenal-[L- acyl-carrier protein oxooctadec- [+ 6 isozymes] [+ 2 isozymes] undecaprenyldiphospho- ∆ 3 ∆ 7 2-carboxy- 2-enoyl-[acp] a [release factor]-N compound a 1,2-diacyl- α murG synthase synthase a trans- -cis- - octanoyl-CoA oxohexanedioate 5-oxofuran- ribulose 1- 6-naphthoate dipalmitoyl an inositol-phospho- β his leu met ile CHC09_RS07060 cerotoyl-CoA 9-enoyl-[acp] palmitoleoyl -methyl-L-glutamine Cys] conjugate 6-enoyl-[acp] acyl-carrier protein N-acetyl-(N-acetyl- -D- (glutamine- (glutamine- S-adenosyl-L-methionine cycle II tetradecenoyl-[acp] 2-yl)-acetate phosphatidate sn-glycerol hydroxyphytoceramide UDP an acetoacetyl-[acp] (1E,3E)-4- phosphate phosphatidate glucosaminyl)muramoyl- hydrolyzing) hydrolyzing) a butanoyl-[acp] ∆ 7 β-ketoadipate hydroxyquinol cis- -tetradecenoyl- hydroxybuta- L-alanyl-γ-D-glutamyl-L- : asnB : asnB uracil degradation L-threonine enol-lactone catechol a sugar RS00690 a sugar L-glutamate [acp]:NAD+ 1,3-diene-1,2,4- hydroxyquinol lysyl-D-alanyl-D-alanine I (reductive) biosynthesis met S-adenosyl-L-methionine cycle I beta-ketoacyl-[acyl- 5-chloromaleylacetate hydrolase: degradation to 2- asparagine asparagine methionine biosynthesis III oxidoreductase: tricarboxylate 1,2-dioxygenase: carrier-protein] pcaC oxopent-4-enoate II synthase synthase uracil adenosyltransferase: CHC09_RS07060 4-oxalmesaconate L-alanine CHC09_RS43925 a (3R,5Z)-3- 1498 a 3,5,7,9,11,13,15- a long-linear 3D-(3,5/4)- a 3-methyl- ammonia (glutamine- (glutamine- L-homoserine synthase II: catechol a uracil 1-myristoylglycerol 5'-deoxy-5'- a very-long- biosynthesis III 5-methyltetrahydropteroyltriglutamate- CHC09_RS31210 SAM 2-oxoglutarate a (7Z)-tetradec- a 3-oxoacyl-[acp] hydratase: 3-oxoadipate propan-1-ol his pimeloyl-CoA ala α-D-glucan trihydroxycyclohexane- ethylnitronate branched 2,3,4- methylmalonate semialdehyde assimilation cycle III CHC09_RS13890 catechol 2,3- 2-maleylacetate FMN ATP hydroxy-tetradec- in 16S rRNA 3-phosphate dIDP hepta-oxo- fluoroadenosine chain fatty acid an anion RS34810 an anion hydrolyzing) hydrolyzing) homoserine kinase: - homocysteine S-methyltransferase: glutamate 7-enoyl-[acp] CHC09_RS19335 purine-nucleoside glycogen/starch/ 1,2-dione saturated fatty acid acyl-CoA 2-hydroxy-4- (2Z,4Z)-2-chloro- NAD(P)- 5-enoyl-[acp]3-oxoacyl-ACP 16S rRNA 1-acyl-sn-glycerol- hexadecanoyl-[PKS-acp]aldo/keto nitronate acyl-CoA methylmalonate- : asnB : asnB 5,6-dihydrouracil CHC09_RS03325 CHC09_RS12950 synthase dioxygenase: L-histidine N(alpha) nucleoside diphosphate 8-amino-7- alpha-glucan 3D-(3,5/4)- O-phospho- cys a 3-oxohexanoyl-[acp] beta-ketoacyl-[acyl- 3-hydroxyhexa- maleylacetate bifunctional dependent alcohol reductase FabG: (uracil(1498)-N(3))- 3-phosphate reductase: phosphorylase: monooxygenase: synthetase: synthetase: semialdehyde ammonium Glu methionine subunit oxobutane-1,2,4- CHC09_RS19350 -methyltransferase: kinase: CHC09_RS23535 oxononanoate trihydroxycyclohexane- cysteine desulfurase: [+ 2 isozymes] carrier-protein] reductase: riboflavin dehydrogenase: methyltransferase: deoD phosphorylase: CHC09_RS15780 CHC09_RS36460 dehydrogenase (CoA predicted glutamine dihydropyrimidinase: L-homoserine adenosyltransferase: tricarboxylate 2,4-dienedioate HMS CHC09_RS36490 acyltransferase: CHC09_RS32910 synthase: 1,2-dione acylhydrolase CHC09_RS18570 CHC09_RS07250 beta: gltD 3-oxoacyl-ACP kinase/FAD CHC09_RS34685 egtD CHC09_RS38375 nucleoside-diphosphate 5-fluoro-5- CHC09_RS00715 [+ 18 isozymes] acylating): mmsA ABC synthetase: asn asn hydA synthase II: 3-oxoacyl-ACP maleylacetate CHC09_RS43930 [+ 9 isozymes] an N 3 - CHC09_RS25115 9-hydroxy-3,5,7,11,13,15-[+ 20 isozymes] CHC09_RS01290 α-D- (decyclizing): iolD [+ 2 isozymes] [+ 18 isozymes] a sugar a sugar threonine synthase: CHC09_RS31210 Glu 4-carboxy-4- a (5Z)-3-oxo- kinase: CHC09_RS38145 deoxy-D-ribose adenine a long-linear [unspecified a 3-methyl- transporter CHC09_RS02105 cysteine desulfurase: L-homocysteine SAM L-alanine reductase: fabG CHC09_RS13890 reductase FabG: reductase: synthetase: [+ 2 isozymes] 1498 8-amino-7- 5-deoxy-D- methylmalonate- dihydropyrimidinase: CHC09_RS35260 hydroxy-2- hercynine tetradec-5- methyluracil 1-myristoyl-2-[+ 6 isozymes] hexaoxohexadecanoyl- coenzyme A glucopyranose α degradation nitrite acetaldehyde branched diphosphate a very long chain of a sugar CHC09_RS02960 biosynthesis II [+ 9 isozymes] a (9Z)-3- 3-oxoadipate ribF dITP 1-phosphate oxononanoate -D-glucan glucuronate diphosphate AMP AMP [+ 2 isozymes] CHC09_RS19135 met SAH beta-ketoacyl-[acyl- CHC09_RS36490 oxoadipate CHC09_RS43930 1-propanal enoyl-[acp] in 16S rRNA palmitoleoyl [PKS-acp] 1-phosphate products] 2,3,4-saturated fatty acyl-CoA semialdehyde threonine synthase: ala oxohexadec- FAD gln a (3R)-3- carrier-protein] [+ 9 isozymes] aldolase/ (2Z)-5-chloro-4- (2Z,4E)-2- phosphatidate fatty acyl-CoA dehydrogenase (CoA 3-ureidopropanoate CHC09_RS03345 pyruvate 9-enoyl-[acp] hydroxyhexanoyl-[acp] synthase II: oxaloacetate hydroxyhex-2-enedioate hydroxyhexa- acylating): mmsA a sugar RS39145 a sugar pyridoxal phosphate- 3-oxoacyl- a (3R)-3- glutamate 5-methyltetrahydropteroyltriglutamate- CHC09_RS13890 2,4-dienedioate H + NADH hydrogencarbonate propanoyl-CoA β thr dependent (3R)-3- ACP a 2,3,4-saturated decarboxylase: synthase -ureidopropionase: - homocysteine S-methyltransferase: hydroxyacyl-[acyl- 4-oxalocrotonate adenosylhomocysteinase: aminotransferase: hydroxyhexanoyl- reductase: fatty acyl-[acp] CHC09_RS19340 subunit beta: gltD CHC09_RS17850 CHC09_RS12950 3-hydroxyacyl-carrier protein] tautomerase: catechol degradation to CHC09_RS09615 CHC09_RS28875 [acyl-carrier protein] fabG 2-oxopent-4-enoate I a sugar RS06630 a sugar [+ 2 isozymes] S-ribosyl-L- [acp] dehydratase: oxaloacetate 2-maleylacetate CHC09_RS15290 a peptide with 1-cis- 4-(cytidine 5'- 1-deoxy-L- a plant soluble (15Z)- Glu β-alanine SAH L-homocysteine ala dehydratase: [+ 9 isozymes] (2S, 3S)-3- O-ureido-L- a 1,4-α-D-glucan 1-palmitoylglycerol homocysteine CHC09_RS13890 (3E)-2-oxohex- roseoflavin 3',5'-ADP arg an N-terminal vaccenoylglycerol- diphospho)-2-C- asp ARP glycero-tetrulose heteroglycan acyl-carrier protein a myristoyl-[acp] CHC09_RS13890 a (3R,9Z)-3- catechol ATP methylaspartate homoserine ATP H O 3-phosphate tetracosenoate 4-carboxy-4- maleylacetate 5'-phosphate L-alanine 3-phosphate methyl-D-erythritol 2 glycogen/starch/ glycogen/starch/ acyl-CoA hydroxyhexadec- 3-enedioate 3'(2'),5'- aminopeptidase 1-acyl-sn-glycerol- 4-(cytidine 5'- argininosuccinate 4-phosphate6,7-dimethyl-8- ACP S-malonyltransferase: 1-acyl-sn-glycerol- hydroxy-2- reductase: catechol 2,3- ATPase: alpha-glucan alpha-glucan synthetase: a (2E)-hex-2-enoyl-[acp] 9-enoyl-[acp] bifunctional bisphosphate arginine deiminase: N: pepN glutamate mutase: 3-phosphate diphospho)- synthase: argG ribityllumazine CHC09_RS40610 3-phosphate cis- oxoadipate CHC09_RS43930 dioxygenase: CHC09_RS35245 phosphorylase: phosphorylase: CHC09_RS18570 RS36460 AMP riboflavin nucleotidase CysQ: 2-C-methyl-D- ACP S-malonyltransferase: CHC09_RS19350 CHC09_RS38955 aminopeptidase CHC09_RS21245 acyltransferase: argininosuccinate synthase: [+ 24 isozymes] acyltransferase: vaccenate hexanoyl-[acyl- aldolase/ kinase/FAD CHC09_RS04785 CHC09_RS00715 CHC09_RS00715 [+ 18 isozymes] 3-oxoadipate HMS N: pepN CHC09_RS25115 erythritol kinase: synthase: CHC09_RS31140 α-D- α-D- CHC09_RS09060 CHC09_RS31170 UDP-N-acetyl-D- Carbohydrate Biosynthesis oxaloacetate 2-oxopent- synthetase: 6,7-dimethyl-8-(1- H + phosphate ADP a plant soluble GDP-mannose biosynthesis UDP-α-D-glucose carrier-protein] L-citrulline Glu [+ 6 isozymes] CHC09_RS04835 CHC09_RS37565 glucopyranose a 1,4-α-D-glucan a malonyl-[acp] [+ 6 isozymes] (Z)-15- glucosamine biosynthesis I a (2E,9Z)- 2,3,4-saturated- a trans-2- decarboxylase: 4-enoate AMP a peptide ala 1,2-dicis- 2-phospho-4-(cytidine glucopyranose heteroglycan 1-palmitoyl- AMP diphosphate α biosynthesis I reductase: a 2,3,4-saturated ribF D-ribityl)lumazine cis- UDP- -D- hexadeca-2,9- fatty-acid-[acp] enoyl-[acyl- CHC09_RS19340 roseoflavin adenine vaccenoyl- 5'-diphospho)-2-C- canavaninosuccinate 1-phosphate 1-phosphate acyl-carrier protein 2-myristoyl tetracosenoyl-CoA RS17080 AMP D-glucopyranose D-glucopyranose CHC09_RS07060 fatty acyl-[acp] vaccenate galactose D-glucopyranose dienoyl-[acp] reductase: carrier protein] dinucleotide phosphatidate methyl-D-erythritol phosphatidate 6-phosphate 6-phosphate 2-oxopent- glucose-6- biosynthesis glucose-6- 6-phosphate palmitoleoyl- CHC09_RS13890 pyruvate formate alpha-D-glucose a hexanoyl-[acp] 4-enoate phosphate UDP-α-D-glucose Calvin-Benson-Bassham cycle phosphate [acp]:NAD+ a (9Z)-3- a (5Z)-3- a (7Z)-3-oxo- 1-cis- uridine 2'3'-cyclic 1402 a DNA containing (25S)-3- a linear malto- (R)-4'- phosphate-specific a cytidine maltohexaose cis- isomerase: UDP-glucose isomerase: Cell Structure Biosynthesis oxidoreductase: biphenyl-2,3-diol an apurinic/ oxocholest- coenzyme A (R)-methylmalonyl-CoA 1-myristoylglycerol phosphopantothenoyl- RS12910 AMP phosphoglucomutase: beta-ketoacyl-[acyl- 2,3,4-saturated fatty oxooctacos- oxotetracos- cys hexadec-7- vaccenoylglycerol- monophosphate in 16S rRNA oligosaccharide a myristoyl-[acp] vaccenate CHC09_RS20305 4-epimerase CHC09_RS20305 CHC09_RS07060 multifunctional 2',3'- glycogen/starch/ 3-phosphate CO D-ribulose-1,5-bisphosphate ribulose bisphosphate carrier-protein] acyl-[acp]:NAD+ 9-enoyl-[acp] 5-enoyl-[acp] enoyl-[acp]3-oxoacyl-ACP 2,3- 3-phosphate 16S rRNA apyrimidinic site 4-en-26-oate acyl-CoA glycogen/starch/ fused acetyl/propionyl- L-cysteine 2 F6P CHC09_RS20910 3-oxoacyl- 3-oxoacyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional F6P GalE: galE carboxylase small synthase II: cysteine dihydroxybiphenyl cyclic-nucleotide 2'- (cytosine(1402)-N(4) alpha-glucan alpha-glucan CoA carboxylase subunit α peptidoglycan biosynthesis I (meso-diaminopimelate containing) a palmitoleoyl-[acp] oxidoreductase: ACP ACP reductase FabG: 3-phosphate deoxyribonuclease synthetase: 3-phosphate phosphopantothenoylcysteine UDP- -D-galactose phosphomannomutase/ Carbohydrate Degradation dioxygenase: phosphodiesterase/ phosphorylase: phosphorylase: subunit: CHC09_RS33080 CHC09_RS13890 CHC09_RS07060 reductase: CHC09_RS36490 1,2-dioxygenase: )-methyltransferase V: CHC09_RS12310 CHC09_RS36460 alpha/methylmalonyl-CoA glutamine-- mannose-6- phosphoglucomutase: reductase: CHC09_RS27325 acyltransferase: acyltransferase: decarboxylase/ cis- RS12850 AMP phosphoribulokinase: form I ribulose UDP-N-acetyl-α-D-glucosamine CHC09_RS16975 5'-nucleotidase/ RsmH: CHC09_RS00715 CHC09_RS00715 decarboxylase subunit fructose-6- phosphate CHC09_RS12315 fabG fabG a (3R,7Z)-3-[+ 9 isozymes] 2-hydroxy-6-oxo- CHC09_RS25115 a 2'- (25S)-3- [+ 5 isozymes] α-D- α-D- CHC09_RS31170 phosphopantothenate-- vaccenate CHC09_RS33100 α-D-glucopyranose a 3-oxooctanoyl-[acp] D-galactose degradation I (Leloir pathway) 3'-nucleotidase: CHC09_RS07880 a linear malto- alpha: CHC09_RS05835 bisphosphate carboxylase 4 deoxyribonucleoside phosphate isomerase, UDP-N-acetylglucosamine L-rhamnose degradation I fructose degradation L-arabinose a cis-delta9-3-[+ 9 isozymes] a (3R,5Z)-3-[+ 9 isozymes] 3-sulfinoalanine hydroxy-hexadec- 6-phenylhexa- 1-cis-vaccenoyl-[+ 6 isozymes] an N - oxocholest-4- glucopyranose maltopentaose glucopyranose [+ 6 isozymes] cysteine ligase CoaBC: coaBC large subunit: rbcL 1-phosphate CHC09_RS10120 oligosaccharide dimyristoyl transaminase class I: manA 1-carboxyvinyltransferase: 3-oxoacyl-ACP degradation I hydroxyC28:1- hydroxytetracos- 7-enoyl-[acp] 2,4-dienoate 2-palmitoleoyl methylcytidine 1402 5'-monophosphate en-26-oyl-CoA 1-phosphate 1-phosphate propanoyl-CoA acyl-carrier protein 4'-phosphopantetheine UTP--glucose- gondoate biosynthesis β-D-galactose α β 3'-UMP phosphatidate cis- (isomerizing) mannose-6- murA reductase: fabG palmitoleate -L- -D-fructofuranose [acp] 5-enoyl-[acp] phosphatidate in 16S rRNA RS05490 AMP : glmS 1-phosphate (anaerobic) L-arabinopyranose vaccenate phosphate UDP-N-acetylglucosamine [+ 9 isozymes] rhamnopyranose 1-phosphate uridylyltransferase: galactose L-rhamnose 1-phosphofructokinase: L-arabinose D-glucosamine isomerase: 1-carboxyvinyltransferase: a (3R)-3- mutarotase: mutarotase: a (7Z)-3- a [lysine-biosynthesis- 7,8- decaprenyl- a 2-methyl CHC09_RS04915 a malonyl-[acp] an oleoyl-[acp] β CHC09_RS14820 isomerase: (S)-1-pyrroline- (2E,9Z)- 1-[18-hydroxyoleyl]- a glycogen 6-phosphate D-ribulose 5-phosphate 3-phospho-D-glycerate CHC09_RS12325 murA CHC09_RS14175 CHC09_RS18815 -D-fructose 1,6- a cis-delta21-3- (E)-2-hexenol xylitol D-glucopyranose protein LysW]-C-terminal- MEP CTP branched 2,3,4- quinoxaline-2- hydroxyoctanoyl-[acp] beta-ketoacyl-[acyl- β-L- CHC09_RS13370 oxohexacos- 5-carboxylate octadecenoyl-CoA 2-lyso-phosphatidate dihydroneopterin pyrophosphoryl-(N acyl-carrier protein cis- phosphoglucosamine D-mannopyranose UDP-α-D-glucose UDP-N-acetyl-α-D- bisphosphate oxo-C40:1-[acp] 1-pyrroline-5- NAD(P)- enoyl-CoA glucose sorbosone 1-acyl-sn-glycerol- γ-(L-glutamyl)-L-glutamate glycogen/starch/ saturated fatty acid carboxyl adenylate RS06740 AMP carrier-protein] aldose epimerase: rhamnopyranose 3-oxoacyl- 7-enoyl-[acp]3-oxoacyl- NAD(P)- 2-C-methyl-D- 3'-triphosphate6-pyruvoyl -acetylglucosamine) acyl-CoA acyl carrier protein: vaccenate mutase: 6-phosphate glucosamine-enolpyruvate (3R)-3- stearate biosynthesis L-arabinose alpha-glucan CHC09_RS27225 carboxylate dependent alcohol dependent alcohol hydratase: dehydrogenase: 3-phosphate acetylglutamate erythritol 4-phosphate -N-acetylmuramyl- CHC09_RS10900 ribose 5-phosphate hydroxyoctanoyl- synthase II: L-rhamnose isomerase: ACP ACP tetrahydrobiopterin peptidoglycan synthetase: CHC09_RS09070 phosphomannomutase/ UDP-N- II (bacteria and plants) dehydrogenase: dehydrogenase: dehydrogenase: CHC09_RS17515 CHC09_RS02910 acyltransferase: cytidylyltransferase: phosphorylase: (pentapeptide) isomerase A: rpiA [acyl-carrier protein] an (11Z)-3-CHC09_RS13890 α-D-galactose isomerase: CHC09_RS18295 reductase: reductase: kinase: argB synthase: CHC09_RS18570 acyl carrier protein: phosphoglucomutase: CHC09_RS18445 CHC09_RS34685 CHC09_RS25115 CHC09_RS00715 ω glycosyltransferase: D-glucosamine acetylenolpyruvoylglucosamine oxo-icos-11- rhaI L-ribulose fabG fabG CHC09_RS34685 enoyl-CoA glucose sorbosone a [lysine-biosynthesis-protein CHC09_RS35070 CHC09_RS09885 α , mono- [+ 18 isozymes] CHC09_RS37630 cis- CHC09_RS12315 dehydratase: 4-(cytidine 5'- (6R)-6-pyruvoyl- -D- a peptidoglycanCHC09_RS37030 a 2-methyl RS37365 AMP 1-phosphate reductase: CHC09_RS35505 a palmitoyl-[acp] enoyl-[acp] [+ 2 isozymes] [+ 2 isozymes] hydratase: dehydrogenase: [+ 6 isozymes] LysW]-C-terminal-γ-(5-phospho- trans,octa-cis a quinoxaline-2- vaccenate phosphoglycerate PRPP biosynthesis I CHC09_RS13890 galactokinase: a cis-delta21-3-[+ 9 isozymes] a (3R,7Z)-3-[+ 9 isozymes] Glu 1-[18-hydroxyoeoyl]-2- diphospho)-2-C- PPP 5,6,7,8- glucopyranose an α-limit dextrin dimer branched α-D-mannose 3-oxoacyl-ACP keto-L-rhamnulose CHC09_RS17360 CHC09_RS29375 i -decaprenyl AMP diphosphate AMP carboxyl-[aryl- UDP-N- kinase: pgk galK (E)-2-hexenal D-xylopyranose [18-hydroxy-lioleoyl]-sn L-glutamyl)-L-glutamate methyl-D-erythritol tetrahydropterin 1-phosphate (mycobacteria) 2,3,4-saturated ribulose-phosphate 1-phosphate hydroxyC40:1- hydroxyhexacos- (S)-3-hydroxy-(9Z) D-glucono- carrier protein] D-ribose 5-phosphate ala UDP-N-acetyl-α-D-muramate Glu reductase FabG: -glycerol 3-phosphate diphosphate acetylglucosamine D-ribose 5- a (2E)-oct-2-enoyl-[acp] α chitobiose degradation [acp] 7-enoyl-[acp] -octadecenoyl-CoA fatty acyl-CoA 3-epimerase: rpe a 3-oxooctadecanoyl- CHC09_RS36490 -D-galactose α L-ribulose 5- 1,5-lactone cis- diphosphorylase/ transketolase: phosphate UDP- -D-glucose RS43690 AMP ribose-phosphate [acp] [+ 9 isozymes] 1-phosphate phosphate N,N'- vaccenate glucosamine-1- D-xylulose 5-phosphate CHC09_RS07300 13-DPG UDP-N- glutamate racemase: octanoyl-[acyl- α pyrophosphokinase: a (3R,11Z)-3- L-rhamnulofuranose glucose and glucose-1-phosphate degradation diacetylchitobiose phosphate N- GDP- -D- acetylmuramate--L- CHC09_RS44645 carrier-protein] 3-oxoacyl- L-ribulose-5- a double (2E,7Z)- cytidine 2',3'-cyclic a (7Z,10Z,13Z,16Z 3-benzyl-3,6 - an N-formyl-L- α,ω-9Z- 1-stearoyl- [+ 3 isozymes] glyceraldehyde- CHC09_RS28925 hydroxy-icos- 6'-phosphate a cis-delta19-3- a 3-oxoicosanoyl- MEP benzyl alcohol a ribonucleoside carbamoyl O-acetyl-L-serine acetyltransferase: mannose alanine ligase: murC reductase: ACP phosphate stranded DNA tetradecenoyl-CoA monophosphate ,19Z)-3-oxodocosa- bis(cysteinylglycine) asp methionylaminoacyl- octadecenedioate an oleoyl-[acp] sn-glycerol 3-phosphate ribose-phosphate 11-enoyl-[acp] rhamnulokinase: α-D- oxo-C38:1-[acp] [acp] 3'-phosphate multifunctional 2',3'- phosphate cis- glmU transketolase: D-sedoheptulose 7-phosphate UDP-N-acetyl-α-D- D-glt CHC09_RS07060 reductase: 4-epimerase 3-oxoacyl- 3-oxoacyl- 1-deoxy-D-xylulose- NAD(P)- DNA gyrase enoyl-CoA multifunctional 2',3'- 7,10,13,16,19-pentaenoyl-[acp] - 6-(hydroxymethyl) aspartate tRNA peptide acyl-CoA 1-acyl-sn-glycerol-3-phosphate O-acetylhomoserine RS41805 AMP dehydrogenase: gap pyrophosphokinase: CHC09_RS32290 glucopyranose N-monoacetylchitobiose cyclic-nucleotide 2'- 3-oxoacyl-ACP membrane vaccenate CHC09_RS07300 muramoyl-L-alanine fabG UDP- AraD: araD ACP ACP 5-phosphate dependent alcohol subunit A: hydratase: cyclic-nucleotide 2'- -diketopiperazine carbamoyltransferase deformylase: synthetase: 3-phosphate aminocarboxypropyltransferase/ bifunctional N- CHC09_RS04805 an octanoyl-[acp] L-rhamnulose 1-phosphate 6'-phosphate phosphodiesterase/ reductase: fabG dipeptidase: [+ 3 isozymes] [+ 9 isozymes] glucose 4- D-xylulose reductase: reductase: reductoisomerase: dehydrogenase: CHC09_RS43290 CHC09_RS17515 phosphodiesterase/ catalytic subunit: def CHC09_RS36460 acyltransferase: cysteine synthase: acetylglucosamine- PRPP 1-phosphate 6-phospho-beta- 3-benzyl-3,6 - UDP-N- a (3R)-3- an (2E,11Z) epimerase CHC09_RS02185 CHC09_RS34685 topoisomerase II: enoyl-CoA 5'-nucleotidase/ [+ 9 isozymes] CHC09_RS20275 [+ 18 isozymes] CHC09_RS34490 1-phosphate 5-phosphate fabG fabG 1-deoxy-D- 5'-nucleotidase/ a (3R,7Z,10Z,13Z,16Z bis(cysteinyl)- 6- CHC09_RS31265 [+ 2 isozymes] CHC09_RS31170 beta-ketoacyl-[acyl- hydroxyoctadecanoyl- -icosa-2,11- rhamnulose- glucosidase: 3'-nucleotidase: N-carbamoyl- a L-methionylaminoacyl- ω-carboxy- cis- acetylmuramoyl- GalE: galE alpha-D-glucose [+ 9 isozymes] [+ 9 isozymes] xylulose 5- [+ 2 isozymes] CHC09_RS22735 hydratase: 3'-nucleotidase: gly [+ 6 isozymes] cysteine synthase B: cysM RS04240 AMP uridyltransferase/ D-sedoheptulose-1,7-bisphosphate carrier-protein] dienoyl-[acp] CHC09_RS15305 a cis-delta19-3- a (3R)-3- a negatively CHC09_RS10120 ,19Z)-3-hydroxydocosa- (hydroxymethyl) formate AMP diphosphate (9Z)-octadec- 1-stearoyl-2- vaccenate dTDP-L-rhamnose L-alanine--D- [acp] 1-phosphate benzaldehyde CHC09_RS17360 CHC09_RS10120 L-aspartate tRNA glucosamine- synthase II: phosphate-specific hydroxyC38:1- hydroxyicosanoyl- phosphate 7,10,13,16,19-pentaenoyl-[acp] -diketopiperazine acyl-carrier protein oleoyl-sn-glycerol acetate cys biosynthesis I glutamate ligase: 3-hydroxyacyl- (2E,11Z)-icosa- aldolase: D-glucopyranose 6-phospho-beta- supercoiled DNA (S)-3-hydroxy-(7Z) 3'-cmp 9-enoyl-CoA 1-phosphate CHC09_RS13890 phosphoglucomutase: [acp] [acp] a ribonucleoside 3-phosphate F6P D-glyceraldehyde 3-phosphate CHC09_RS06965 [acp] dehydratase: 2,11-dienoyl- CHC09_RS32295 glucosidase: -tetradecenoyl-CoA acetyltransferase: α-D-glucopyranose CHC09_RS20910 CHC09_RS13890 [acp] reductase: α-D- quinoprotein CHC09_RS18095 cis- UDP-α-D- RS40590 AMP CHC09_RS30580 1-phosphate meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- a 3-oxodecanoyl-[acp] CHC09_RS07060 (S)-lactaldehyde DHAP phosphomannomutase/ glucose N-acetyl-D- vaccenate glucose-1-phosphate a (2E)-octadec- glucopyranose (E)-4-hydroxy-3- N-acetyl-α-D- sedoheptulose galactose phosphoglucomutase: dehydrogenase: glucokinase: glucosamine D-glucosamine a (5Z)-3- (2R,3S)-3- (S)-3- a 6-(N-acetyl-α- 4-fumaryl- 2-phospho-4-(cytidine 5'- an odd numbered thymidylyltransferase: L-alanyl-D-glutamate 2-enoyl-[acp] 1-phosphate a cis-delta17-3- a 3-oxoglutaryl- (Z)-hex-3-en-ol DMKH a 2-oxo NADH menadione H + glucosamine bisphosphate aldolase: 3-oxoacyl-ACP a gondoyl-[acp] CHC09_RS12315 CHC09_RS37790 CHC09_RS08300 oxododec- methylbut-2-en- isopropylmalate hydroxyhexadecanoyl- 2 D-glucosaminyl)- L-ornithine acetoacetate a pimeloyl-[acp] ala diphospho)-2-C-methyl-D-erythritol straight chain rfbA D-ala 6-phosphate oxo-C36:1-[acp] [acp] methyl ester carboxylate CHC09_RS37320 reductase: fabG steroyl-[acp] 5-enoyl-[acp] NAD(P)- 1-yl diphosphate 3-isopropylmalate CoA bifunctional 1-phosphatidyl- fumarylacetoacetase: 2-C-methyl-D- NADH oxidoreductase 2,3,4-saturated 1-phosphate triose-phosphate dTDP-α-D-glucose UDP-N- alpha-D-glucose D-glucono- 3-oxoacyl- 3-oxoacyl- 3-oxoacyl-ACP 4-hydroxy-3- enoyl-CoA ornithine- 8-amino-7- cis- reductase: dependent alcohol dehydratase demethylmenaquinone 1D-myo-inositolGlcNAc-PI de- fahA erythritol 2,4- (quinone) subunit F: fatty acidacyl-CoA RS23930 AMP UDP-N- isomerase: D-alanine--D- acetylmuramoyl-L- [+ 9 isozymes] phosphate-specific 1,5-lactone ACP ACP reductase FabG: methylbut-2-en-1- hydratase: -oxo-acid oxononanoate vaccenate dTDP-glucose 4,6- CHC09_RS07060 xylose degradation I dehydrogenase: large subunit: leuC methyltransferase/2- N-acetylase: fumarylacetoacetate cyclodiphosphate CHC09_RS26685 synthetase: acetylglucosamine CHC09_RS07345 alanine ligase: alanyl-D-glutamate-- a (3R)-3- phosphoglucomutase: D-glucopyranose reductase: reductase: CHC09_RS36490 yl diphosphate CHC09_RS17360 6-(α-D- transaminase: synthase: dehydratase: rfbB gluconolactonase: CHC09_RS34685 3-isopropylmalate methoxy-6-polyprenyl-1,4- CHC09_RS14770 hydrolase: synthase: NADH-quinone CHC09_RS18570 diphosphorylase/ CHC09_RS02655 2, 6-diaminopimelate hydroxydecanoyl-[acp] CHC09_RS20910 6-phosphate D-mannose degradation fabG fabG a (3R,5Z)-3-[+ 9 isozymes] synthase: glucosaminyl)- rocD CHC09_RS01290 an odd numbered dTDP-4-dehydro-6- a stearoyl-[acp] CHC09_RS06595 enoyl-CoA acetate CHC09_RS35075 [+ 18 isozymes] glucosamine-1- ligase: acyl-CoA hydrolysis phosphomannomutase/ D-xylopyranose [+ 9 isozymes] [+ 9 isozymes] [+ 2 isozymes] CHC09_RS02175 dehydratase benzoquinol methylase L-glutamate-5- a proteinogenic CHC09_RS37690 acyl-carrier protein 8-amino-7- oxidoreductase subunit cis- deoxy-α-D-glucopyranose D-alanine--D- 3-hydroxydecanoyl- a cis-delta17-3- a (3R)-3- hydroxydodec- 2-C-methyl-D- hydratase: 1-phosphatidyl- straight chain RS39690 AMP β-D-fructose 1,6-bisphosphate DHAP CHC09_RS07865 xylose gluconolactonase: D-mannopyranose (Z)-3-hexanal small subunit: leuD UbiE: CHC09_RS26645 semialdehyde amino acid acetoacetate fumarate oxononanoate 2-C-methyl-D-erythritol- G: CHC09_RS26690 diphosphate AMP vaccenate phosphate N- alanine ligase: [acp] dehydrase: phosphoglucomutase: hydroxyC36:1- hydroxyglutaryl- 5-enoyl-[acp] erythritol-2,4- CHC09_RS17515 1D-myo-inositol CMP 2,3,4-saturated CHC09_RS37710 (2S)-2- 2,4-cyclodiphosphate + acetyltransferase: dTDP-4- a 2,3,4-saturated CHC09_RS12315 isomerase: 6-phosphate trans-hexadec- MQH menadiol NAD mannose-6- [acp] [acp] methyl ester cyclodiphosphate 2 fatty acyl CoA dehydrorhamnose CHC09_RS23095 α CHC09_RS13890 fatty acyl CoA xylA isopropylmalate glmU UDP-N-acetyl- -D-muramoyl- acyl-CoA acetoin degradation D-gluconate 2-enoyl-CoA 3,5-epimerase: γ D-glucopyranose D-xylulose phosphate D-alanyl-D-alanine L-alanyl- -D-glutamyl- thioesterase: cis- bifunctional N- CHC09_RS30710 a (2E)-dec-2-enoyl-[acp] stearate 6-phosphate isomerase, RS07700 AMP meso-2,6-diaminopimelate CHC09_RS30345 vaccenate acetylglucosamine- xylulokinase: class I: manA 2251 1-stearoyl- dTDP-4-dehydro- coenzyme A acetoin a 3-oxopimeloyl- 3'-UMP a (3R)-3- (2E,7Z)- guanosine a negatively a ferrocytochrome an acyl-[acyl- ditrans,octacis- decanoyl-[acyl- acyl-CoA xylB a cis-delta15-3- D-mannitol hydantoin L-allo-threonine DMKH2-13 stearoyl-CoA sn-glycerol a palmitoleoyl-[acp] 1-palmitoylglycerol 1-phosphate class II fructose- β-L-rhamnose a 2,3,4-saturated[+ 4 isozymes] acetoin dehydrogenase: mannose-6- hydroxyacyl-CoA hexadecenoyl-CoA in 23S rRNA supercoiled DNA undecaprenyldiphospho- UDP-N- carrier-protein] synthetase: oxo-C34:1-[acp] [acp] methyl ester b carrier protein] 3-phosphate uridyltransferase/ xylulose kinase: NAD(P)- multifunctional 2',3'- enoyl-CoA enoyl-CoA 23S rRNA DNA dihydropyrimidinase: low specificity L- bifunctional acyl-CoA5 3-phosphate N-acetyl-(N- bisphosphate aldolase: dTDP-4- acetylmuramoyl- fatty acid CHC09_RS41905 phosphate 3-oxoacyl- 3-oxoacyl- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- cis- glucosamine- reductase: CHC09_RS18570 CHC09_RS05740 dependent alcohol cyclic-nucleotide 2'- hydratase: hydratase: (guanosine(2251) topoisomerase hydA threonine aldolase: demethylmenaquinone desaturase: acetylglucosaminyl) RS38020 AMP CHC09_RS37320 dehydrorhamnose tripeptide--D-alanyl- acetoin dehydrogenase: isomerase: ACP ACP 3-phosphate 3-phosphate vaccenate CHC09_RS07060 [+ 18 isozymes] dehydrogenase: phosphodiesterase/ CHC09_RS17360 CHC09_RS17360 I: topA 1-phosphate D- alanine ligase: D-xylulose CHC09_RS27430 CHC09_RS12325 reductase: reductase: -2'-O)- dihydropyrimidinase: CHC09_RS08175 methyltransferase/2- CHC09_RS12840 acyltransferase: muramoyl-L-alanyl- acyltransferase: reductase: CHC09_RS34685 5'-nucleotidase/ acetyltransferase: CHC09_RS07860 5-phosphate acetaldehyde acetyl-CoA F6P fabG fabG enoyl-CoA enoyl-CoA methyltransferase DNA topoisomerase CHC09_RS19135 [+ 2 isozymes] methoxy-6-polyprenyl-1,4- [+ 4 isozymes] CHC09_RS31170 γ-D-isoglutaminyl- CHC09_RS31170 CHC09_RS24825 a decanoyl-[acp] stearoyl-CoA 3'-nucleotidase: CHC09_RS30580 [+ 9 isozymes] [+ 9 isozymes] [+ 2 isozymes] hydratase: hydratase: RlmB: IV subunit A: benzoquinol methylase a ferricytochrome [+ 6 isozymes] N-(β-D-asparaginyl)peptidoglycan [+ 6 isozymes] [+ 2 isozymes] a cis-delta15-3- a (3R)-3- aldehydo- N-carbamoylglycine acetaldehyde gly oleoyl-CoA a 1-stearoyl 2- 1-palmitoyl-2- cis- UDP-N-acetyl- UDP-N-acetyl-α-D-muramoyl-L- CHC09_RS10120 CHC09_RS17515 CHC09_RS17515 CHC09_RS35145 CHC09_RS29175 UbiE: CHC09_RS26645 b di-trans,octa-cis-L-lysyl-D-alaninea glycosyltransferase:peptidoglycan RS05935 AMP di-trans,octa-cis- beta-ketoacyl-[acyl- hydroxyC34:1- hydroxypimeloyl- D-mannose 2-O- 5 acyl-carrier protein acyl-sn-glycerol acyl-carrier protein palmitoleoyl vaccenate α dTDP-β-L-rhamnose alanyl-γ-D-glutamyl-meso-2,6- uridine (S)-3-hydroxy-(7Z) -undecaprenyl dimer -D-glucosamine carrier-protein] [acp] [acp] methyl ester a cis-2-enoyl-CoA methylguanosine 2251 a relaxed DNA menaquinol-13 3-phosphate CHC09_RS37030 phosphatidate undecaprenyl phosphate -hexadecenoyl-CoA diphosphate (tetrapeptide) diaminopimeloyl-D-alanyl-D-alanine synthase II: in 23S rRNA CHC09_RS13890 superpathway of pyrimidine Nucleoside and Nucleotide Degradation cis- pyrimidine deoxyribonucleotides RS17365 AMP deoxyribonucleosides degradation vaccenate dephosphorylation a 3- an organic (2E,11Z)- guanosine D-ribulose-1,5- 1-cis- a 2,3,4-saturated 1-cis- a 3-oxododecanoyl-[acp] a cis-delta13-3- 3'-cmp + a cis- oxodocosanoyl- a 3-oxosteroid 2',3'-cyclic H malonyl-CoA porphobilinogen 5'-deoxyadenosine DMK-12 bisphosphate vaccenoylglycerol- CTP 1,2-diacyl-sn- a palmitoleoyl-[acp] vaccenoylglycerol- undecaprenyldiphospho- 2'-deoxycytidine nucleoside triphosphate oxo-C32:1-[acp] hydroperoxide octadecenoyl-CoA vaccenoyl-[acp] [acp] thioredoxin- multifunctional 2',3'- 3-ketosteroid-delta- enoyl-CoA monophosphate type III polyketide hydroxymethylbilane S-methyl-5'- ribulose 3-phosphate glycerol 3-phosphate 3-phosphate N-acetylmuramoyl-L-alanyl- 3-oxoacyl-ACP biotin-carboxyl carrier pyrophosphohydrolase: 3-oxoacyl- 3-oxoacyl- multifunctional 2',3'- bifunctional 1-acyl-sn-glycerol- phosphatidate 1-acyl-sn-glycerol- cis- γ protein assembly dependent thiol cyclic-nucleotide 2'- 1-dehydrogenase: hydratase: synthase: synthase: hemC thioadenosine demethylmenaquinone bisphosphate RS18570 AMP -D-glutamyl-meso-2,6- reductase: fabG cytidine deaminase: purine nucleotides degradation II (aerobic) CHC09_RS11370 ACP ACP cyclic-nucleotide 2'- 3-phosphate cytidylyltransferase: 3-phosphate dCTP dCMP peroxidase: phosphodiesterase/ CHC09_RS16895 CHC09_RS17360 CHC09_RS35050 phosphorylase: carboxylase vaccenate diaminopimeloyl-D-alanyl-D-alanine [+ 9 isozymes] a [biotin carboxyl- CHC09_RS38410 reductase: reductase: phosphodiesterase/ hydroxymethylbilane methyltransferase/2- acyltransferase: CHC09_RS41540 acyltransferase: CHC09_RS24250 5'-nucleotidase/ type III polyketide CHC09_RS24585 small subunit: undecaprenyldiphospho- carrier protein]-L-lysine cytidine deaminase: thymidine fabG fabG 3-ketosteroid-delta- enoyl-CoA 5'-nucleotidase/ synthase: methoxy-6-polyprenyl-1,4- CHC09_RS31170 phosphatidate CHC09_RS31170 Metabolic Regulator Biosynthesis a (3R)-3- [+ 5 isozymes] 3'-nucleotidase: 1-dehydrogenase: hydratase: synthase: CHC09_RS05165 benzoquinol methylase CHC09_RS33080 muramoylpentapeptide beta-N- CHC09_RS04705 AMP dUTP diphosphatase: a cis-delta13-3-[+ 9 isozymes] a (3R)-3-[+ 9 isozymes] 3'-nucleotidase: 5-deoxy-α-ribose [+ 6 isozymes]1,2-dicis- cytidylyltransferase: [+ 1-cis-vaccenoyl-6 isozymes] hydroxydodecanoyl-[acp] biotin--[acetyl-CoA- thymidine CHC09_RS10120 CHC09_RS17590 CHC09_RS17515 CHC09_RS40810 adenine UbiE: CHC09_RS26645 3-phospho- cis- RS17275 AMP acetylglucosaminyltransferase: CHC09_RS01600 an alcohol CHC09_RS10120 preuroporphyrinogen 1-phosphate 2-phosphoglycolate CHC09_RS02225 carboxylase] ligase: phosphorylase: hydroxyC32:1- hydroxydocosanoyl- a 3-oxo- (S)-3-hydroxy-(11Z) D-glycerate acyl-carrier protein vaccenoyl- acyl-carrier protein 2-palmitoleoyl vaccenate ppGpp biosynthesis murG (3R)-3- 2'-deoxyuridine cytidine octoketide menaquinol-12 a CDP-2,3,4-saturated- trehalose trehalose biosynthesis I CHC09_RS04450 bifunctional nucleoside triphosphate [acp] [acp] 1 3'-GMP phosphatidate phosphatidate hydroxydodecanoyl- CHC09_RS04700 D -steroid -octadecenoyl-CoA diacylglycerol biosynthesis V lipid II (meso a [biotin carboxyl- metallophosphatase/ pyrophosphohydrolase: D-glucopyranose diaminopimelate containing) [acyl-carrier protein] carrier protein]-N thymine 5'-nucleotidase: CHC09_RS11370 pppGpp UDP-α-D-glucose oleate RS17275 AMP a glycogen dehydratase: 6 -biotinyl-L-lysine CHC09_RS09155 dUTP dUMP 6-phosphate uracil a 3- a 1-alkyl-sn adenosine β bifunctional (p)ppGpp trehalose-6- CHC09_RS13890 (2E,5Z)- (2E,9Z)- methyl -D-glucoside (2R)-phospho- 2+ sn-glycero-3- isoamylase: phosphorylase: [+ 2 isozymes] IMP a cis-delta11-3- an alcohol scyllo-inosose acetyl-CoA protoporphyrin IX Mg a cis- 1-palmitoylglycerol 1-myristoylglycerol synthetase/guanosine- phosphate oxodocosanoyl- -glycerol 3- dodecenoyl-CoA hexadecenoyl-CoA 2',3'-cyclic 6-phosphate 3-sulfolactate phosphoethanolamine a palmitoleoyl-[acp] glgX CHC09_RS04700 oxo-C30:1-[acp] 2-keto-myo-inositol vaccenoyl-[acp] 3-phosphate 3-phosphate Aromatic Compound Biosynthesis 5-hydroxy-CTP 5-hydroxy-CMP 3-oxoacyl- [acp] 3-oxoacyl- NAD(P)- phosphate enoyl-CoA enoyl-CoA monophosphate 6-phospho-beta- 2-phosphosulfolactate acetyl-CoA carboxylase protoporphyrin IX 1-acyl-sn-glycerol- glycerophosphodiester 1-acyl-sn-glycerol- 3',5'-bis(diphosphate) 3'- guanosine 3'- a maltodextrin synthase: a (2E)-dodec-2-enoyl-[acp] adenosine IMP 1-acyl-sn-glycerol- multifunctional 2',3'- a [biotin carboxyl- ACP dependent alcohol hydratase: hydratase: glucosidase: dehydratase: phosphatase: carboxyltransferase magnesium chelatase: phosphodiesterase: oleate pyrophosphohydrolase: diphosphate 5'- CHC09_RS23430 GMP dehydrogenase: ACP 3-phosphate cyclic-nucleotide 2'- 3-phosphate 3-phosphate RS18570 AMP carrier-protein dimer]- S-methyl-5'- dehydrogenase: CHC09_RS17515 CHC09_RS17360 CHC09_RS15305 CHC09_RS20680 CHC09_RS32305 subunit: CHC09_RS30365 CHC09_RS12460 CHC09_RS22725 CHC09_RS23785 triphosphate 3'- malto- chorismate biosynthesis I dodecanoyl-[acyl- reductase: reductase: acyltransferase: phosphodiesterase/ acyltransferase: acyltransferase: trehalose-6- 6 adenosine CHC09_RS11065 thioadenosine diphosphatase: oligosyltrehalose 2,3-dihydroxybenzoate carrier-protein] N -biotinyl-L-lysine uracil 2-deoxy-α-D- fabG fabG CHC09_RS06615 enoyl-CoA enoyl-CoA 6-phospho-beta- myo-inosose-2 2-phosphosulfolactate acetyl-CoA carboxylase magnesium chelatase: CHC09_RS31170 glycerophosphodiester CHC09_RS31170 [+ 2 isozymes] phosphate bifunctional [+ 2 isozymes] degradation II CHC09_RS31170 5'-nucleotidase/ biosynthesis biotin carboxylase: ribose 1-phosphate deaminase: [+ 2 isozymes] hydratase: hydratase: glucosidase: dehydratase: iolE phosphatase: carboxyltransferase CHC09_RS13530 phosphodiesterase: CHC09_RS31540 synthase: treY synthase: D-erythrose reductase: biotin carboxylase: metallophosphatase/ S-methyl-5'- a cis-delta11-3-[+ 9 isozymes] a (3R)-3-[+ 9 isozymes] a 2-acyl-1-alkyl-[+ 6 isozymes] 3'-nucleotidase: 3D-(3,5/4)- [+ 61-palmitoyl-2- isozymes] [+ 61-myristoyl-2- isozymes] CHC09_RS43190 CHC09_RS44185 CHC09_RS33620 4-phosphate CHC09_RS07060 5'-nucleotidase: an aldehyde CHC09_RS17360 CHC09_RS17515 CHC09_RS10120 CHC09_RS18095 trihydroxycyclohexane- subunit: CHC09_RS21695 Mg-protoporphyrin CHC09_RS17815 oleate RS17365 AMP a maltooligosyl- α α CHC09_RS08280 chorismate CHC09_RS43190 [+ 2 isozymes] XMP thioadenosine hydroxyC30:1- hydroxydocosanoyl- sn-glycerol (S)-3-hydroxy-(5Z) (S)-3-hydroxy-(9Z) β-D-glucose acyl-carrier protein cis-vaccenoyl acyl-carrier protein palmitoleoyl , -trehalose [+ 6 isozymes] S-methyl-5'- MeOH 1,2-dione (2R)-3-sulfolactate malonyl-CoA sn-glycerol trehalose 3-deoxy-7- CHC09_RS09155 [acp] [acp] 3-phosphate -dodecenoyl-CoA -hexadecenoyl-CoA 3'-AMP phosphatidate ethanolamine phosphatidate 6-phosphate a dodecanoyl-[acp] a [carboxyl-carrier thioadenosine 6-phosphate 3-phosphate ppGpp malto- phosphoheptulonate 6 2-deoxy-D-ribose [+ 2 isozymes] GTP trehalose- protein dimer]-N - inosine bifunctional phosphorylase: oligosyltrehalose synthase: 5-phosphate phosphatase: isochorismate carboxybiotinyl-L-lysine metallophosphatase/ CHC09_RS24585 oleate RS05935 AMP guanosine trehalohydrolase: CHC09_RS10170 purine-nucleoside 5'-nucleotidase: a (6Z)-3- 1-oleyl-2-lyso- (S)-3- a ribonucleoside β-D-glucose an oxidized arbutin-6- D-cellobiose nucleoside otsB beta-ketoacyl-[acyl- 5-MTR-1-P a 3-oxohexacosanoyl- a nucleoside a (6S)-5- oleate a 2,3,4-saturated a 2,3,4-saturated 2- treZ 3-deoxy-7- isochorismatase: carrier-protein] deoxyribose- phosphorylase: CHC09_RS09155 oxooctadec- met phosphatidate hydroxyhexanoyl- 2',3'-cyclic 6-phosphate coenzyme F phosphate Glu 6'-phosphate diphosphate kinase: [acp] diphosphate GTP H O 420 formyltetrahydrofolate fatty acyl-[acp] lysophosphatidate 4'-phosphopantetheine ATP α,α-trehalose phosphoheptulonate CHC09_RS13870 phosphate deoD purine-nucleoside [+ 2 isozymes] 6-enoyl-[acp] 1-acyl-sn-glycerol- CoA nucleoside- phosphate 2 glucose-6- 6-phospho-beta- acyl-CoA 6-phospho-beta- CHC09_RS23535 GDP α,α-trehalose synthase II: 3-oxoacyl- bifunctional 3-oxoacyl- enoyl-CoA multifunctional 2',3'- bifunctional 1-acyl-sn-glycerol- bifunctional (p)ppGpp laurate aldolase: phosphorylase: 3-phosphate diphosphate kinase: ribosome phosphate glucosidase: synthetase: glucosidase: pantetheine-phosphate pyrophosphokinase: trehalose synthase: aroF isochorismatase: CHC09_RS13890 ACP ornithine ACP hydratase: cyclic-nucleotide 2'- folylpolyglutamate 3-phosphate oleate RS38020 AMP nucleoside- synthetase/guanosine- deoD small subunit- CHC09_RS15305 CHC09_RS31540 biosynthesis IV 3-deoxy- CHC09_RS19180 deoC hypoxanthine xanthosine reductase: acyltransferase: reductase: CHC09_RS38145 dehydrogenase CHC09_RS15305 CHC09_RS18570 acyltransferase: adenylyltransferase: diphosphate kinase: 3',5'-bis(diphosphate) 3'- acyl-CoA acetyltransferase/ CHC09_RS17515 phosphodiesterase/ dependent synthase/ D-arabino- (2S,3S)-2,3- purine-nucleoside fabG CHC09_RS25115 fabG nucleoside (coenzyme- 6-phospho-beta- [+ 18 isozymes] 6-phospho-beta- CHC09_RS31170 CHC09_RS02545 CHC09_RS38145 pyrophosphohydrolase: synthetase: deoxyribose- xanthine N-acetylglutamate enoyl-CoA 5'-nucleotidase/ GTPase A: rsgA dihydrofolate α-maltose heptulosonate dihydroxy-2,3- a 3-oxotetradecanoyl-[acp] guanine [+ 6 isozymes] F420): fgd glucosidase: glucosidase: CHC09_RS18570 phosphate dehydrogenase: phosphorylase: a (3R,6Z)-3-[+ 9 isozymes] synthase: a (3R)-3-[+ 9 isozymes] diphosphate kinase: 3'-nucleotidase: 6-phospho synthase: [+a 62,3,4-saturated isozymes] pantetheine-phosphate CHC09_RS23785 maltose alpha-D- dihydrobenzoate dioleoyl hydratase: [+ 4 isozymes] a reduced diphosphate AMP oleoyl-CoA CHC09_RS18095 7-phosphate aldolase: CHC09_RS38575 deoD CHC09_RS31010 CHC09_RS23535 CHC09_RS10120 D-glucono- CHC09_RS18095 CHC09_RS38115 adenylyltransferase: coaD [+ 18 isozymes] hydroxyoctadec- hydroxyhexacosanoyl- CHC09_RS17360 + 1,2-diacyl-sn oleate RS07700 AMP [+ 2 isozymes] glucosyltransferase: 3-dehydroquinate 3-oxoacyl-ACP N-acetyl-L- phosphatidate a nucleoside a ribonucleoside phosphate GDP H coenzyme F β-D-glucose a (6S)-5- D-glucopyranose acyl-carrier protein 3'-dephospho-CoA deoC 6-enoyl-[acp] [acp] trans-hex-2- 420 1,5-lactone hydroquinone D-glucopyranose treS 6-phosphate 6-phosphate -glycerol 3- GDP synthase: reductase: fabG lauroyl-CoA methionine enoyl-CoA triphosphate 3'-phosphate formyltetrahydrofolate α,α-trehalose phosphate CHC09_RS31295 [+ 9 isozymes] D-glyceraldehyde 2,3- acetaldehyde 3-dehydroquinate dihydroxybenzoate a (3R)-3- 3-phosphate superpathway of purine deoxyribonucleosides degradation oleate RS39690 AMP xanthine (24E)-3α,7α- a 2-methoxy-6-all- synthase: hydroxytetradecanoyl-[acp] an (11Z)-3- a 1-acyl-sn (3S)- 3-oxo-4-pregnene- 4-methyl-3- salicin 6- adenine 1518 / a 1-acyl-sn a (2R)-2-hydroxy a 7,8-dihydro-8- acetaldehyde a 3-oxotetracosanoyl- a ribonucleoside β succinyl-CoA an acyl-[acyl- oxooctadec- -glycerol 3- hydroxyadipyl- dihydroxy-5 - 1519 -glycerol 3- trans-polyprenyl- even numbered CHC09_RS22620 dehydrogenase xanthine [acp] GTP diphosphate 20-carboxyl-CoA oxoadipate phosphate adenine in 16S rRNA carrier protein] oxoguanine in DNA (3R)-3- 11-enoyl-[acp] phosphate CoA cholest-24-enoyl-CoA 3-ketosteroid-9- 3-oxoadipate 6-phospho-beta- phosphate 1,4-benzoquinol straight chain (acetylating): 2'-deoxyguanosine 3-oxoacyl- 1-acyl-sn-glycerol- 3-oxoacyl- enoyl-CoA ribonucleoside- 3-alpha,7- 16S rRNA 1-acyl-sn-glycerol- bifunctional bifunctional DNA- hydroxymyristoyl- dehydrogenase: CoA-transferase: 3-dehydroquinate phosphatidylglycerol ACP ACP adenylate/guanylate diphosphate alpha, 12-alpha- alpha-hydroxylase: glucosidase: (adenine(1518)-N(6)/ 3-phosphate demethylmenaquinone 2,3,4-saturatedacyl-CoA formamidopyrimidine oleate RS23930 AMP [acyl-carrier protein] CHC09_RS16910 CHC09_RS38575 2'-deoxyadenosine 3-phosphate hydratase: biosynthesis II reductase: reductase: cyclase domain- reductase trihydroxy-5-beta- CHC09_RS16950 CHC09_RS34795 CHC09_RS15305 adenine(1519)-N(6))- methyltransferase/2- fatty acid glycosylase/ type II 3- dehydratase: purine-nucleoside acyltransferase: CHC09_RS17360 acyltransferase: synthetase: (non-plastidic) acetyl-CoA urate fabG containing protein: 3-ketosteroid-9- 3-oxoadipate 6-phospho-beta- dimethyltransferase methoxy-6-polyprenyl-1,4- DNA-(apurinic or CHC09_RS13890 phosphorylase: fabG CHC09_RS31170 enoyl-CoA subunit alpha: cholest-24-enoyl- CHC09_RS31170 CHC09_RS18570a (R)-2-hydroxy dehydroquinate CHC09_RS05135 CoA-transferase: glucosidase: RsmA: apyrimidinic site) lyase: DHAP deoD [+ 9 isozymes] [+ 6 isozymes] [+ 9 isozymes] CHC09_RS09780 CoA hydratase: alpha-hydroxylase: [+ 6 isozymes] benzoquinol methylase [+ 18 isozymes] dehydratase: aroQ adenosine a (3R,11Z)-3- a 1-acyl-2- a (3R)-3- hydratase: a 1,2-diacyl- even numbered [+ 3 isozymes] CHC09_RS16890 CHC09_RS16960 CHC09_RS34800 CHC09_RS18095 6 CHC09_RS048401518 UbiE: CHC09_RS26645 CHC09_RS02510 NAD(P)H- hydroxyoctadec- palmitoyl-sn hydroxytetracosanoyl- CHC09_RS17515 a 2'- [+ 2 isozymes] (24R,25R)-3α,7α,24- 9α-hydroxy-androst- N -dimethyladenine acyl-carrier protein sn-glycerol a 6-methoxy-3-methyl- diphosphate AMP straight chain oleate RS40590 AMP a (2E)-tetradec-2-enoyl-[acp] purine ribonucleosides degradation deaminase: cyclic-GMP 4-methyl-3- β-D-glucose an apurinic site 7,8-dihydro- 3-dehydroshikimate purine-nucleoside trans-2,3- β succinate /N 6 -dimethyladenine 1519 dependent glycerol- 11-enoyl-[acp] -glycerol 3- [acp] deoxyribonucleoside trihydroxy-5 - 4-en-3-one-17- oxoadipyl-CoA salicyl alcohol 6-phosphate 3-phosphate 2-all-trans-polyprenyl- 2,3,4-saturated within DNA 8-oxoguanine CHC09_RS44185 phosphorylase: dehydroadipyl-coA myristoyl-[acyl- 3-phosphate phosphate 5'-diphosphate cholestanoyl CoA propanoyl-CoA in 16S rRNA 1,4-benzoquinol fatty acyl CoA shikimate [+ 2 isozymes] carrier-protein] dehydrogenase: deoD dehydrogenase: adenosine purine-nucleoside oleate RS04240 AMP reductase: CHC09_RS15945 CHC09_RS31310 phosphorylase: UDP cholest-4- (S)-3- (11Z)-(S)-3- 3-oxo-23,24- 2E)-tetradec- 3-oxo-2-(cis-2'-pentenyl) (2E,6Z,9Z,12Z,15Z,18Z,21Z) 2-methoxy-6-all ditrans,octacis- CHC09_RS07060 an unsulfurated a [ThiI sulfur-carrier glycerophosphoglycerol NAD(P)-dependent adenosine deoD a protein hydroxybutanoyl- hydroxyhexadec- bisnorchol- 2-enoyl-CoA -cyclopentane-1-(3R- cys cys trans-octaprenyl- DL-allothreonine undecaprenyldiphospho- 2'-deoxyinosine ribonucleoside- en-3-one [sulfur carrier] -tetracosaheptaenoyl-CoA protein]-L-cysteine shikimate glycerol-3- deaminase: 2-deoxy-α-D- 3-ketosteroid-delta- CoA 11-enoyl-CoA 4-en-22-oate enoyl-CoA hydroxybutanoyl)-CoA enoyl-CoA glycerophosphodiester 1,4-benzoquinol a myristoyl-[acp] proteasome enoyl-CoA enoyl-CoA 3-ketosteroid-9- enoyl-CoA cysteine cysteine bifunctional serine N-acetyl-(N- phosphate CHC09_RS44185 diphosphate 1-dehydrogenase: hydratase: hydratase: phosphodiesterase: ribose 1-phosphate subunit hydratase: alpha-hydroxylase: hydratase: desulfurase: desulfurase: demethylmenaquinone hydroxymethyltransferase: acetylglucosaminyl) oleate RS41805 AMP shikimate kinase: dehydrogenase: reductase hydratase: CHC09_RS17515 CHC09_RS17515 [+ 2 isozymes] beta: prcB CHC09_RS16895 CHC09_RS17360 CHC09_RS02960 CHC09_RS02960 CHC09_RS17815 methyltransferase/2- CHC09_RS09555 muramoyl-L-alanyl-γ- CHC09_RS31300 beta-ketoacyl-[acyl- subunit alpha: CHC09_RS17515 CHC09_RS17515 CHC09_RS16950 CHC09_RS02675 3-ketosteroid-delta- enoyl-CoA enoyl-CoA glycerophosphodiester D-isoglutaminyl-N-(β- carrier-protein] sn-glycerol CHC09_RS09780 proteasome enoyl-CoA enoyl-CoA 3-ketosteroid-9- enoyl-CoA cysteine cysteine methoxy-6-polyprenyl-1,4- serine xanthosine adenosine inosine guanosine 1-dehydrogenase: hydratase: hydratase: phosphodiesterase: D-asparaginyl)-L-lysyl-peptidoglycan shikimate 3- synthase II: 3-phosphate 2-deoxy-D-ribose subunit hydratase: hydratase: alpha-hydroxylase: hydratase: desulfurase: desulfurase: benzoquinol methylase hydroxymethyltransferase: ribonucleoside- CHC09_RS17590 CHC09_RS17360 CHC09_RS17360 phosphate CHC09_RS13890 purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside alpha: prcA CHC09_RS17515 CHC09_RS07250 (3S)-hydroxy- CHC09_RS07250 CHC09_RS22725 UbiE: CHC09_RS26645 CHC09_RS03245 di-trans,octa-cisD-alanyl-D-alanineglycosyltransferase: oleate RS43690 AMP 5-phosphate diphosphate cholest- CHC09_RS17360 CHC09_RS17360 3-one-9-hydroxy-CHC09_RS16960 (S)-3- 3-oxo-2-(cis-2'-pentenyl) a [ThiI sulfur- 6-methoxy-3-methyl- a peptidoglycan phosphorylase: phosphorylase: phosphorylase: phosphorylase: (2E,11Z)-hexadec- a sulfurated sn-glycerol -undecaprenyl CHC09_RS37030 3-phosphoshikimate 1- a peptide a peptide dien-3-one crotonyl-CoA 23,24-bisnorchol- hydroxytetradecanoyl- -cyclopentane-1-(E- ala (6Z,9Z,12Z,15Z,18Z,21Z) ala carrier protein]-S- glycerol 2-all-trans-octaprenyl- gly acetaldehyde dimer (E. faeciums) a 3-oxohexadecanoyl-[acp] deoD deoD deoD reductase: 2,11-dienoyl-CoA [sulfur carrier] 3-phosphate diphosphate carboxyvinyltransferase: deoD deoxyribose- 4-en-22-oate CoA buta-2-enoyl)-CoA -tetracosahexaenoyl-CoA sulfanyl-L-cysteine 1,4-benzoquinol a 1-acyl-sn CHC09_RS09785 aroA phosphate 3-oxoacyl-ACP -glycerol 3- dUDP oleate RS37365 AMP 5-enolpyruvoyl- aldolase: deoC shikimate 3- reductase: fabG phosphate deoxyribose- [+ 9 isozymes] 1-acyl-sn-glycerol- thymine degradation α-D-ribose- UTP and CTP dephosphorylation I phosphate dCDP (2E)-dec-2- 3-oxo-4- 3-oxo-23,24- 3-oxo-2-(cis-2'-pentenyl) a damaged a 2-deoxystreptamine 6-methoxy-2-all- 2-methoxy-6-all an electron- a DNA containing 3-phosphate phosphate an L-cysteinyl- an N-modified NADH H + chorismate a (3R)-3- 1-phosphate cys cobyrinate pregnene-20- bisnorchol-1,4- -cyclopentane-1-(3R- antibiotic trans-octaprenyl- trans-hexaprenyl- an apurinic/ UTP aldolase: deoC enoyl-CoA [tRNA Cys ] DNA pyrimidine aminoacyl-[tRNA] transfer quinone synthase: hydroxyhexadecanoyl-[acp] acyltransferase: thymine ribonucleoside- cobyrinate a,c- enoyl-CoA DNA glycosylase: aminoglycoside N(3) 1,4-benzoquinone 1,4-benzoquinol NADH apyrimidinic site oleate RS06740 AMP lanthionine carboxyl-CoA3-ketosteroid-delta- aminoacyl-tRNA dien-22-yl-CoA3-ketosteroid-9- hydroxyoctanoyl)-CoAenoyl-CoA aminoacyl-tRNA bifunctional bifunctional bifunctional DNA- CHC09_RS31305 CHC09_RS31170 diphosphate diamide synthase: hydratase: CHC09_RS01880 -acetyltransferase: (3R)-3- synthetase: 1-dehydrogenase: hydrolase: alpha-hydroxylase: hydratase: hydrolase: demethylmenaquinone demethylmenaquinone oxidoreductase [+ 6 isozymes] CTP synthase: reductase CHC09_RS23185 formamidopyrimidine acetaldehyde D-glyceraldehyde 3-phosphate CHC09_RS41250 CHC09_RS12470 CHC09_RS17515 CHC09_RS02780 bifunctional DNA- CHC09_RS02780 (quinone) subunit F: chorismate hydroxypalmitoyl- a 1,2-diacyl- 5,6-dihydrothymine D-ribose 5- CHC09_RS36360 subunit alpha: CHC09_RS16895 CHC09_RS16950 CHC09_RS17360 methyltransferase/2- methyltransferase/2- glycosylase/ cobyrinate a,c- enoyl-CoA formamidopyrimidine aminoglycoside N(3) CHC09_RS26685 [acyl-carrier protein] sn-glycerol phosphate acetaldehyde CHC09_RS09780 cystathionine 3-ketosteroid-delta- aminoacyl-tRNA 3-ketosteroid-9- enoyl-CoA aminoacyl-tRNA methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- DNA-(apurinic or oleate RS05490 AMP dihydropyrimidinase: UMP diamide synthase: hydratase: -acetyltransferase: dehydratase: 3-phosphate CTP beta-synthase: 1-dehydrogenase: hydrolase: alpha-hydroxylase: glycosylase/ hydrolase: benzoquinol methylase benzoquinol methylase NADH-quinone apyrimidinic site) lyase: hydA dehydrogenase ribonucleoside- hydratase: CHC09_RS13890 bifunctional CHC09_RS23460 CHC09_RS17360 DNA-(apurinic or CHC09_RS09280 UbiE: CHC09_RS26645 UbiE: CHC09_RS26645 oxidoreductase phosphatidate (acetylating): CHC09_RS11490 (S)-3- 3-oxo-23,24-CHC09_RS17590 CHC09_RS04795 9α-hydroxy-3-oxo-CHC09_RS16960 3-oxo-2-(cis-2'-pentenyl)CHC09_RS17515 an N 3 -acetyl-2- CHC09_RS04795 3-methyl-6-methoxy- 6-methoxy-3-methyl-2- CHC09_RS02510 dihydropyrimidinase: diphosphate cob(II)yrinate apyrimidinic site) lyase: an N-modified an uncharged subunit G: a 3'-terminal a 5'-phospho- cytidylyltransferase: metallophosphatase/ CHC09_RS16910 lanthionine hydroxydecanoyl- bisnorchol-1,4- a tRNA Cys cys 23,24-bisnorchol- -cyclopentane-1-(E- 2-octaprenyl-1,4- all-trans-hexaprenyl- CHC09_RS19135 reductase: a,c-diamide deoxystreptamine tRNA a (2E)-hexadec-2-enoyl-[acp] CHC09_RS02225 5'-nucleotidase: CHC09_RS02510 amino acid benzoquinone 1,4-benzoquinol CHC09_RS26690 unsaturated sugar [DNA] pseudouridine CHC09_RS09785 CoA dien-22-yl-CoA 1,4-dien-22-yl-CoA octa-2-enoyl)-CoA antibiotic oleate RS12850 AMP CMP CHC09_RS09155 acetyl-CoA an apyrimidinic an electron- + phosphatidate 3-(carbamoylamino)- degradation NAD palmitoyl-[acyl- CDP site in DNA transfer quinol cytidylyltransferase: 2-methylpropanoate bifunctional [+ 2 isozymes] carrier-protein] CHC09_RS41540 β-ureidopropionase: metallophosphatase/ uridine pseudouridine reductase: 6 a CDP- CHC09_RS17850 5'-nucleotidase: 5-deoxy-D- 4-hydroxy- 3-oxo-2-(cis-2'-pentenyl) 2-methoxy-6-all an O - oleate RS12910 AMP an L-asparaginyl- NMN NaMN uroporphyrinogen-III a [protein]- γ CHC09_RS07060 4-methyl-2- 3'-AMP -cyclopentane-1-(3R- 3'-dephospho- cobalt-precorrin-7 glycerophosphoserine trans-nonaprenyl- methylguanine 4-( -L-glutamylamino)butanoate diacylglycerol CHC09_RS09155 glucuronate IMP [tRNA Asn ] ATP L-cysteine (R)-3-amino-2- [+ 2 isozymes] pseudouridine 5-deoxy- oxoglutarate multifunctional 2',3'- multifunctional 2',3'- hydroxyhexanoyl)-CoA bifunctional CoA bifunctional cobalt- glycerophosphodiester 1,4-benzoquinol in DNA gamma-glutamyl-gamma- a palmitoyl-[acp] CDP-diacylglycerol-- 4-carboxy-4- multifunctional 2',3'- aminoacyl-tRNA enoyl-CoA dephospho- bifunctional methylated-DNA-- methylpropanoate 5'-phosphate glucuronate bifunctional cyclic-nucleotide 2'- cyclic-nucleotide 2'- uroporphyrinogen-III precorrin-7 (C(5))- phosphodiesterase: aminobutyrate hydrolase: glycerol-3-phosphate 3- hydroxy-2- cyclic-nucleotide 2'- hydrolase: hydratase: CoA kinase: demethylmenaquinone [protein]-cysteine S- cytidine isomerase: metallophosphatase/ phosphodiesterase/ phosphodiesterase/ C-methyltransferase/ methyltransferase CbiE/ CHC09_RS22725 CHC09_RS02085 oleate RS17080 AMP phosphatidyltransferase: oxoadipate phosphodiesterase/ CHC09_RS02780 CHC09_RS17360 methyltransferase/2- methyltransferase: pseudouridine- iolB 5'-nucleotidase: CHC09_RS06640 5'-nucleotidase/ 5'-nucleotidase/ 5'-nucleotidase/ uroporphyrinogen- decarboxylating cobalt- glycerophosphodiester methoxy-6-polyprenyl-1,4- CHC09_RS04330 gamma-glutamyl-gamma- pgsA 5'-phosphate aldolase/ CHC09_RS09155 aminoacyl-tRNA enoyl-CoA 5-deoxy- 3'-nucleotidase: 3'-nucleotidase: III synthase: dephospho- precorrin-6B (C(15) phosphodiesterase: aminobutyrate hydrolase: 1-(3-sn- glycosidase: oxaloacetate 3'-nucleotidase: hydrolase: hydratase: benzoquinol methylase methylated-DNA-- glucuronate [+ 2 isozymes] CHC09_RS10120 CHC09_RS10120 CHC09_RS05160 CoA kinase: )-methyltransferase CHC09_RS17815 CHC09_RS02090 palmitate phosphatidyl) decarboxylase: CHC09_RS10120 CHC09_RS04795 3-oxo-2-(cis-2'-pentenyl)CHC09_RS17515 6-methoxy-3-methyl-2-UbiE: CHC09_RS26645 [protein]-cysteine S- CHC09_RS01655 inosine CHC09_RS07500 CbiT: CHC09_RS01100 oleate RS36460 AMP -sn-glycerol isomerase: CHC09_RS19340 Asn β [+ 2 isozymes] [+ 2 isozymes] uroporphyrinogen-III sn-glycerol all-trans-nonaprenyl- tRNA asn 1-( -D β -cyclopentane-1-(E- + ser methyltransferase: 4-aminobutanoate Glu acyl-CoA uracil iolB adenosine -D- ADP coenzyme A H 3-phosphate 3-phosphate 5-dehydro- pyruvate ribofuranosyl) hexa-2-enoyl)-CoA C-methyltransferase: cobalt-precorrin-8 1,4-benzoquinol CHC09_RS23035 synthetase: ribosylnicotinate cobA a [protein]-S- Amine and Polyamine Degradation 2-deoxy-D- nicotinamide a guanine in DNA CHC09_RS18570 methyl-L-cysteine gluconate precorrin-2 [+ 18 isozymes] an L-1- creatinine degradation I urea degradation I phosphatidyl- 4-aminobutanoate 4-aminobutanoate allantoin degradation urea degradation II palmitoyl-CoA degradation I degradation III to ureidoglycolate (R)-4-hydroxy- 2-methoxy-6-all 4 sn-glycerol a [protein]- (S)-4-hydroxy- (24R,25R)- (3E)-5-chloro-2- a double-stranded D-ribulose DNA combined 1-stearoyl- an O - a nascent peptidoglycan predicted creatinine I (urea producing) 4-aminobutanal a [glutamine- a [protein]- urea urea L-tyrosine 4-methyl-2- 2-oxopentanoate 3α,7α,12α,24- oxopent-3-enoate oligonucleotide 5-phosphate with exogenous a stearoyl-[acp] sn-glycerol trans-heptaprenyl- methylthymine with (L-alanyl-γ-D- creatininase: 4-aminobutanoate 4-aminobutanoate dADP synthetase]- ATP L-cysteine lipid II (meso ABC urea (S)-(+)-allantoin urease subunit phosphate oxoglutarate 2-keto-4- tetrahydroxy-5β- 2-keto-4- oligoribonuclease: aminobutyraldehyde bifunctional DNA to form a 3-phosphate 1,4-benzoquinol in DNA glutamyl-meso-2,6- urea urea CHC09_RS41625 protein-tyrosine- 4-carboxy-4- L-tyrosine 1-acyl-sn-glycerol- bifunctional methylated-DNA-- diaminopimelate transporter 4-aminobutyrate- 4-aminobutyrate- carboxylase: uca gamma: ribonucleoside- pentenoate cholestanoyl 3-alpha,7-CoA pentenoate CHC09_RS24200 dehydrogenase: adenylyltransferase/ 3,4-dihydroxy- recombinational diaminopimeloyl- allantoinase phosphatase: hydroxy-2- Holliday junction 3-phosphate demethylmenaquinone [protein]-cysteine S- containing) of urea creatine -2-oxoglutarate -2-oxoglutarate [+ 2 isozymes] CHC09_RS31450 diphosphate hydratase: alpha, 12-alpha- hydratase: CHC09_RS36065 sulfurtransferase 2-butanone- junction D-alanyl-D-alanine) AllB: allB CHC09_RS02820 oxoadipate bifunctional resolvase RuvX: acyltransferase: methyltransferase/2- methyltransferase: peptidoglycan transaminase: transaminase: urea-1-carboxylate reductase trihydroxy-5-beta- CHC09_RS13030 MoeZ: 4-phosphate pentapeptide allantoate [+ 2 isozymes] CHC09_RS13030 oligoribonuclease/ gamma- CHC09_RS31325 CHC09_RS31170 methoxy-6-polyprenyl-1,4- CHC09_RS04330 glycosyltransferase: gabT gabT subunit alpha: phosphotyrosine aldolase/ cholest-24-enoyl- CHC09_RS10330 a nascent peptidoglycan succinate succinate ammonium 2-keto-4- 2-keto-4- PAP phosphatase aminobutyraldehyde synthase/GTP [+ 6 isozymes] benzoquinol methylase CHC09_RS37030γ allophanate CHC09_RS09780 protein oxaloacetate CoA hydratase: crossover junction 1-stearoyl-2- methylated-DNA-- with (L-alanyl- -D- semialdehyde semialdehyde allantoicase: pentenoate pentenoate NrnA: dehydrogenase: bifunctional cyclohydrolase II: UbiE: CHC09_RS26645 di-trans,octa-cis hydrolase subunit phosphatase: decarboxylase: (24E)-3α,7α,12CHC09_RS16890α- resolution ofendodeoxyribonuclease stearoyl-sn 6-methoxy-3-methyl-2- [protein]-cysteine S- glutamyl-meso-2,6- ribonucleoside- hydratase: hydratase: CHC09_RS02020 CHC09_RS36125 glutamine-synthetase CHC09_RS31145 acyl-carrier protein -undecaprenyl NAD-dependent succinate- 1: CHC09_RS05585 alc CHC09_RS03260 CHC09_RS19340 trihydroxy- 1-deoxy-L- recombinationalRuvC: CHC09_RS31575 -glycerol 3- all-trans-heptaprenyl- methyltransferase: diaminopimeloyl- sarcosine semialdehyde diphosphate a [protein]- CHC09_RS16905 CHC09_RS16905 a nucleoside 5'- adenylyltransferase/ diphosphate succinate- [+ 2 isozymes] pyruvate 5β-cholest- 4-aminobutanoate glycero-tetrulose formate junction phosphate 1,4-benzoquinol CHC09_RS23035 D-alanyl-D-alanine) (S)-ureidoglycolate reductase: 2-oxopent- 5-chloro-4-hydroxy- monophosphate deadenyltransferase: a [protein]-S- semialdehyde dehydrogenase: L-tyrosine 24-enoyl-CoA 4-phosphate formation of two a thymine in DNA pentapeptide sarcosine CHC09_RS09785 4-enoate 2-oxopentanoate a [glutamineCHC09_RS08820 methyl-L-cysteine sarcosine oxidase: dehydrogenase: CHC09_RS36125 ammonium intact strands dehydrogenase: ADP synthetase]-O CHC09_RS00580 CHC09_RS13025 Detoxification 4 CHC09_RS00585 succinate -(5'-adenylyl) [+ 2 isozymes] -L-tyrosine gly succinate reactive oxygen species degradation arsenate arginine dependent acid resistance β-D-glucose a plant a uridine 38- (S)-5-amino-3- 1-stearoyl- all trans-decaprenyl- a DNA containing phosphoenol an [HPr]- detoxification DHAP NAD + NADPH a ribonucleoside acetyl-CoA a [protein]- superoxide 6-phosphate 3'-GMP arabinogalactan 40 in tRNA cob(I)yrinate a palmitoyl-[acp] sn-glycerol 2-methoxy-6- S methyl II (glutaredoxin) dGDP 5'-monophosphate GTP ATP oxohexanoate p L-cysteine pyruvate L-histidine inositol-3- NAD(P)-dependent a,c-diamide 1,4-benzoquinol phosphotriester oxidized GTP and arg multifunctional 2',3'- type I NAD(P)(+) tRNA multifunctional 2',3'- 3-keto-5- 1-acyl-sn-glycerol-3-phosphate bifunctional methylated-DNA-- phosphoenolpyruvate- superoxide dismutase: arsenate ribonucleoside- phosphate arabinogalactan glycerol-3- bifunctional cob(I)yrinic acid dGTP detoxification pyruvoyl- cyclic-nucleotide 2'- transhydrogenase pseudouridine(38- cyclic-nucleotide 2'- aminohexanoate 3-phosphate demethylmenaquinone [protein]-cysteine S- -protein CHC09_RS43480 arsenate reductase: diphosphate synthase: endo-1,4-beta- phosphate 3,4-dihydroxy- a,c-diamide dependent arginine phosphodiesterase/ (Re/Si-specific) 40) synthase TruA: phosphodiesterase/ cleavage protein: acyltransferase: methyltransferase/2- methyltransferase: phosphotransferase: superoxide dismutase: CHC09_RS43130 reductase CHC09_RS23030 galactosidase: dehydrogenase: 2-butanone- adenosyltransferase: decarboxylase: 5'-nucleotidase/ subunit alpha: CHC09_RS10800 5'-nucleotidase/ CHC09_RS35450 CHC09_RS31170 methoxy-6-polyprenyl-1,4- CHC09_RS04330 CHC09_RS18530 CHC09_RS07120 dGTP GTP subunit alpha: CHC09_RS18240 CHC09_RS02675 4-phosphate cobO arsenate CHC09_RS06450 inositol-3- 3'-nucleotidase: CHC09_RS24595 RluA family 3'-nucleotidase: 3-keto-5- [+ 6 isozymes] benzoquinol methylase phosphoenolpyruvate- CHC09_RS09780 arabinogalactan synthase/GTP 1-stearoyl- methylated-DNA-- reductase ArsC: agmatine phosphate CHC09_RS10120 NAD(P)H- pseudouridine ATP:cob(I)alamin -protein hydrogen peroxide endo-1,4-beta- NAD(P)(+) CHC09_RS10120 cyclohydrolase II: aminohexanoate 2-palmitoyl- 6-methoxy-3-methyl-UbiE: CHC09_RS26645 [protein]-cysteine S- CHC09_RS16340 ribonucleoside- synthase: dependent glycerol- synthase: adenosyltransferase: acyl-carrier protein phosphotransferase: ptsP galactosidase: transhydrogenase [+ 2 isozymes] CHC09_RS31145 cleavage protein: sn-glycerol 2-all-trans-decaprenyl- methyltransferase: an [HPr protein]- arsenite 8-oxo-dGTP 8-oxo-GTP diphosphate CHC09_RS14460 guanosine adenosyl-CHC09_RS03180 3-phosphate (Re/Si-specific) CHC09_RS07785 CHC09_RS05505 1,4-benzoquinol CHC09_RS23035 π catalase: CHC09_RS18245 a pseudouridine 38- a ribonucleoside 2,5-diamino-6- (S)-3- 3-phosphate a DNA without N -phospho- pyruvate reductase: dehydrogenase: subunit beta: [+ 2 isozymes] PPP cobyrinate a [protein]-S- CHC09_RS01060 8-oxo-dGTP Ins(3)P a galactotetraose 40 in tRNA (5-phospho-D- i acetoacetate aminobutanoyl- S methyl L-histidine CHC09_RS09785 CHC09_RS15945 CHC09_RS24590 a,c-diamide methyl-L-cysteine p [+ 2 isozymes] diphosphatase: formate ribosylamino) CoA phosphotriester GDP sn-glycerol + H O hydroxyl radical CHC09_RS04630 NADP NADH pyrimidin- 2 3-phosphate arsenite 8-oxo-GMP 4(3H)-one O 8-oxo-dGMP 2

O O UQ H O O UQ H O O O 1-(β-D an electron- a carbohydrate 2 2 2 2 2 2 2 a carbohydrate 2+ glycine betaine glycine betaine glycine betaine glycine betaine ribofuranosyl) Co 2+ 2+ + transfer a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate ammonium H O H O O H O O H O H O a carbohydrate a carbohydrate a carbohydrate a carbohydrate 2+ Mg Mg H ammonium ammonium gly gly gly gly 2 2 2 2 2 2 2 nicotinamide Mg quinone

predicted ABC predicted ABC RS21520 RS20415 RS25440 transporter of RS28985 RS27995 RS06045 RS21510 RS00590 RS40415 RS42020 RS23995 RS02450 CoxB CtaD RS20090 CtaD RS20215 RS08440 CtaD RS27640 RS36150 RS14810 transporter of RS15415 RS42720 CorA RS05045 RS36910 RS08400 a carbohydrate a carbohydrate

glycine betaine glycine betaine glycine betaine glycine betaine 1-(β-D Co 2+ a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate ammonium a carbohydrate a carbohydrate a carbohydrate a carbohydrate Mg 2+ Mg 2+ a reduced a reduced a reduced a reduced a reduced ribofuranosyl) 2+ an oxidized ammonium ammonium a carbohydrate gly gly gly gly a carbohydrate Mg c-type c-type c-type c-type c-type nicotinamide c-type cytochrome cytochrome cytochrome cytochrome cytochrome an electron-cytochrome UQH UQH transfer 2 2 an oxidized an oxidized an oxidized an oxidized an oxidized quinol c-type c-type c-type c-type c-type cytochrome cytochrome cytochrome cytochrome cytochrome This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.