CURRICULUM VITAE
Date Prepared: 12/01/2011
Name (complete with degrees): Mark Oldham, PhD
Primary academic appointment: Professor, Radiation Oncology Physics
Primary academic department (not DUAP): Radiation Oncology
Secondary appointment (if any) –(department): Associate Professor, Biomedical Engineering
Present academic rank and title (if any): Professor
Date and rank of first Duke Faculty appointment: January, 2004, Associate Professor
Specialty certification(s) and dates (Month/Day/Year):
American Board of Medical Physics Certification 2001 Radiation Oncology Physics re-cert 2010
American Board of Radiology Certification (equivalency) ` 2005 Radiation Oncology Physics
Date of birth: 10/22/1965 Place (include city/state/country): Manchester, United Kingdom
Citizen of: USA and UK (Dual)
Visa status (if applicable):
Education: Institution Date (year) Degree Major
Manchester University, UK 1987 BSc, Class 1 Physics University of Newcastle-Upon-Tyne, UK 1991 PhD Physics
Scholarly societies (Alpha Omega Alpha, Sigma Xi, Phi Beta Kappa, etc): none
Professional training and academic career (chronologically, beginning with first postgraduate position):
Institution Position/Title Dates
The Institute of Cancer Research (ICR) & Postdoctoral Research Fellow 1992-1995 The Royal Marsden NHS Trust, Sutton, UK
The Institute of Cancer Research (ICR) Lecturer in Medical Physics 1995-1998 & The Royal Marsden NHS Trust, Sutton, UK
William Beaumont Hospital, Clinical Staff Physicist 1998-2003 Royal Oak, MI USA
Duke University Medical Center Associate Professor, (Primary) 2004 - 2011 Radiation Oncology Physics Associate Professor, Biomedical 2006 -2008 Engineering (Secondary) 2010+ Director of Radiation Therapy Track, 2005-Present Medical Physics Graduate Program
Publications: (Do not include submitted papers or papers in preparation: List separately those papers in press.) PLEASE NUMBER ALL ENTRIES SEQUENTIALLY (1# OLDEST)
1. Referred journals: (Referred journals are scientific publications that have active editorial boards and a system of critical review of all submissions for publications.)
1. Oldham M, Edge R, Lowes F, A Decametric Scale Investigation of the Gravitational Constant, Geophysical Journal International, 113(1) p83-94, 1993 2. Oldham M, Webb S. The optimization and inherent limitations of 3D conformal radiotherapy treatment plans of the prostate. Br J Radiol. 1995 Aug;68(812):882-93. 3. Oldham M, Neal AJ, Webb S. The optimisation of wedge filters in radiotherapy of the prostate. Radiother Oncol. 1995 Dec;37(3):209-20. 4. Oldham M, Neal A, Webb S. A comparison of conventional 'forward planning' with inverse planning for 3D conformal radiotherapy of the prostate. Radiother Oncol. 1995 Jun;35(3):248-62.
5. Neal AJ, Oldham M, Dearnaley DP. Comparison of treatment techniques for conformal radiotherapy of the prostate using dose-volume histograms and normal tissue complication probabilities. Radiother Oncol. 1995 Oct;37(1):29-34. 6. Webb S, Oldham M. A method to study the characteristics of 3D dose distributions created by superposition of many intensity-modulated beams delivered via a slit aperture with multiple absorbing vanes. Phys Med Biol. 1996 Oct;41(10):2135-53. 7. Oldham M, Webb S. Intensity-modulated radiotherapy by means of static tomotherapy: a planning and verification study. Med Phys. 1997 Jun;24(6):827-36. 8. Bedford JL, Oldham M, Hoess A, Evans PM, Shentall GS, Webb S. Methods for transferring patient and plan data between radiotherapy treatment planning systems. Br J Radiol. 1997 Jul;70(835):740-9. 9. Rowbottom CG, Webb S, Oldham M. Improvements in prostate radiotherapy from the customization of beam directions. Med Phys. 1998 Jul;25(7 Pt 1):1171-9. 10. Oldham M, McJury M, Baustert IB, Webb S, Leach MO. Improving calibration accuracy in gel dosimetry. Phys Med Biol. 1998 Oct;43(10):2709-20.
11. Oldham M, Khoo VS, Rowbottom CG, Bedford JL, Webb S. A case study comparing the relative benefit of optimizing beam weights, wedge angles, beam orientations and tomotherapy in stereotactic radiotherapy of the brain. Phys Med Biol. 1998 Aug;43(8):2123-46.
12. Oldham M, Baustert I, Lord C, Smith TA, McJury M, Warrington AP, Leach MO, Webb S. An investigation into the dosimetry of a nine-field tomotherapy irradiation using BANG-gel dosimetry. Phys Med Biol. 1998 May;43(5):1113-32. 13. Guzel Z, Bedford JL, Childs PJ, Nahum AE, Webb S, Oldham M, Tait D. A comparison of conventional and conformal radiotherapy of the oesophagus: work in progress. Br J Radiol. 1998 Oct;71(850):1076-82. 14. Rowbottom CG, Webb S, Oldham M. Is it possible to optimize a radiotherapy treatment plan? Int J Radiat Oncol Biol Phys. 1999 Feb 1;43(3):698-9. 15. Rowbottom CG, Webb S, Oldham M. Beam-orientation customization using an artificial neural network. Phys Med Biol. 1999 Sep;44(9):2251-62. 16. Rowbottom CG, Oldham M, Webb S. Constrained customization of non-coplanar beam orientations in radiotherapy of brain tumours. Phys Med Biol. 1999 Feb;44(2):383-99. 17. Hepworth S, McJury MJ, Oldham M, Morton EJ, Doran SJ Dosae mapping of inhomogeneities positioned in radiosensitive polymer gels. Nucl. Instr. Meth. In Phys. Res. A 422 pp756-760, 1999
18. McJury M, Tapper PD, Cosgrove VP, Murphy PS, Griffin S, Leach MO, Webb S, Oldham M. Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Phys Med Biol. 1999 Oct;44(10):2431-44. 19. McJury M, Oldham M, Leach MO, Webb S. Dynamics of polymerization in polyacrylamide gel (PAG) dosimeters: (I) ageing and long-term stability. Phys Med Biol. 1999 Aug;44(8):1863-73.
20. Khoo VS, Oldham M, Adams EJ, Bedford JL, Webb S, Brada M. Comparison of intensity-modulated tomotherapy with stereotactically guided conformal radiotherapy for brain tumors. Int J Radiat Oncol Biol Phys. 1999 Sep 1;45(2):415-25. 21. Bedford JL, Khoo VS, Oldham M, Dearnaley DP, Webb S. A comparison of coplanar four-field techniques for conformal radiotherapy of the prostate. Radiother Oncol. 1999 Jun;51(3):225-35. 22. McJury M, Oldham M, Cosgrove VP, Murphy PS, Doran S, Leach MO, Webb S. Radiation dosimetry using polymer gels: methods and applications. Br J Radiol. 2000 Sep;73(873):919-29. 23. Low DA, Markman J, Dempsey JF, Mutic S, Oldham M, Venkatesan R, Haacke EM, Purdy JA. Noise in polymer gel measurements using MRI. Med Phys. 2000 Aug;27(8):1814-7. 24. Baustert IC, Oldham M, Smith TA, Hayes C, Webb S, Leach MO. Optimized MR imaging for polyacrylamide gel dosimetry. Phys Med Biol. 2000 Apr;45(4):847-58. 25. Oldham M, Siewerdsen JH, Shetty A, Jaffray DA. High resolution gel-dosimetry by optical-CT and MR scanning. Med Phys. 2001 Jul;28(7):1436-45. 26. Oldham M, “Radiation physics and applications in therapeutic medicine”, Phys. Ed. 36 p460-467 Nov (2001)
27. Oldham M, Sapareto SA, Li XA, Allen J, Sutlief S, Wong OC, Wong JW. Practical aspects of in situ 16O (gamma,n) 15O activation using a conventional medical accelerator for the purpose of perfusion imaging. Med Phys. 2001 Aug;28(8):1669-78. 28. Oldham M, Siewerdsen JH, Kumar S, Wong J, Jaffray DA. Optical-CT gel-dosimetry I: basic investigations. Med Phys. 2003 Apr;30(4):623-34. 29. Oldham M. Optical-CT scanning of polymer gels. J Phys. 2004;3:122-135. 30. Oldham M, Kim L. Optical-CT gel-dosimetry. II: Optical artifacts and geometrical distortion. Med Phys. 2004 May;31(5):1093-104. 31. Létourneau D, Gulam M, Yan D, Oldham M, Wong JW. Evaluation of a 2D diode array for IMRT quality assurance. Radiother Oncol. 2004 Feb;70(2):199-206.
32. Oldham M, Létourneau D, Watt L, Hugo G, Yan D, Lockman D, Kim LH, Chen PY, Martinez A, Wong JW. Cone-beam-CT guided radiation therapy: A model for on-line application. Radiother Oncol. 2005 Jun;75(3):271.E1-8. 33. Oldham M, Kim L, Hugo G. Optical-CT imaging of complex 3D dose distributions. J Phys. 2005 Apr;5745:138-146. 34. Létourneau D, Wong JW, Oldham M, Gulam M, Watt L, Jaffray DA, Siewerdsen JH, Martinez AA. Cone- beam-CT guided radiation therapy: technical implementation. Radiother Oncol. 2005 Jun;75(3):279-86. 35. Das SK, Baydush AH, Zhou S, Miften M, Yu X, Craciunescu O, Oldham M, Light K, Wong T, Blazing M, Borges-Neto S, Dewhirst MW, Marks LB. Predicting radiotherapy-induced cardiac perfusion defects. Med Phys. 2005 Jan;32(1):19-27.
36. Yin FF, Das S, Kirkpatrick J, Oldham M, Wang Z, Zhou SM. Physics and imaging for targeting of oligometastases. Semin Radiat Oncol. 2006 Apr;16(2):85-101.
37. Oldham M. 3D dosimetry by optical-CT scanning. J Phys. 2006;56:58-71.
38. Oldham M, Sakhalkar H, Oliver T, Wang YM, Kirpatrick J, Cao Y, Badea C, Johnson GA, Dewhirst M. Three-dimensional imaging of xenograft tumors using optical computed and emission tomography. Med Phys. 2006 Sep;33(9):3193-202. 39. Oldham M, Sakhalkar H, Guo P. A dual-purpose CCD based micro-optical-CT scanning system. J Phys. 2006 Dec 1;56(1):199-202. 40. Oldham M, Guo P, Gluckman G, Adamovics J. IMRT verification using a radiochromic/optical-CT dosimetry system. J Phys. 2006;56:221-224. 41. Oldham M, Guo P, Adamovics J, Sakhalkar H, Wang Z, Yin F. Towards four dimensional (4D) dosimetry for radiation-therapy. J Phys. 2006;56:225-227. 42. Guo PY, Adamovics JA, Oldham M. Characterization of a new radiochromic three-dimensional dosimeter. Med Phys. 2006 May;33(5):1338-45. 43. Guo P, Adamovics J, Oldham M. Quality assurance in 3D dosimetry by optical-CT. J Phys. 2006 Dec 1;56(1):191-194. 44. Guo P, Adamovics J, Oldham M. A practical three-dimensional dosimetry system for radiation therapy. Med Phys. 2006 Oct;33(10):3962-72. 45. Godfrey DJ, Yin FF, Oldham M, Yoo S, Willett C. Digital tomosynthesis with an on-board kilovoltage imaging device. Int J Radiat Oncol Biol Phys. 2006 May 1;65(1):8-15.
46. Sakhalkar HS, Dewhirst M, Oliver T, Cao Y, Oldham M. Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing. Phys Med Biol. 2007 Apr 21;52(8):2035-54.
47. Oldham M, Sakhalkar H, Wang YM, Guo P, Oliver T, Bentley R, Vujaskovic Z, Dewhirst M. Three- dimensional imaging of whole rodent organs using optical computed and emission tomography. J Biomed Opt. 2007 Jan-Feb;12(1):014009.
48. Godfrey DJ, Ren L, Yan H, Wu Q, Yoo S, Oldham M, Yin FF. Evaluation of three types of reference image data for external beam radiotherapy target localization using digital tomosynthesis (DTS). Med Phys. 2007 Aug;34(8):3374-84.
49. Beyer GP, Mann GG, Pursley JA, Espenhahn ET, Godfrey D, Oldham M, Carrera TB, Bolick N abd Scarantino CW, An implantable MOSFET dosimeter for the measurement of radiation dose in tissue during cancer therapy. IEEE Sensors Journal, Vol3 (1) pp38-51, Jan 2008 50. Sakhalkar HS, Oldham M. Fast, high-resolution 3D dosimetry utilizing a novel optical-CT scanner incorporating tertiary telecentric collimation. Med Phys. 2008 Jan;35(1):101-11.
51. Oldham M, Sakhalkar H, Oliver T, Allan Johnson G, Dewhirst M. Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography. J Biomed Opt. 2008 Mar-Apr;13(2):021113. 52. Oldham M, Sakhalkar H, Guo P, Adamovics J. An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques. Med Phys. 2008 May;35(5):2072-80.
53. Kim E, Bowsher J, Thomas AS, Sakhalkar H, Dewhirst M, Oldham M. Improving the quantitative accuracy of optical-emission computed tomography by incorporating an attenuation correction: application to HIF1 imaging. Phys Med Biol. 2008 Oct 7;53(19):5371-5383. 54. Sakhalkar HS, Adamovics J, Ibbott G, Oldham M. A comprehensive evaluation of the PRESAGE/optical- CT 3D dosimetry system. Med Phys. 2009 Jan;36(1):71-82. 55. Sakhalkar H, Sterling D, Adamovics J, Ibbott G, Oldham M. Investigation of the feasibility of relative 3D dosimetry in the Radiologic Physics Center Head and Neck IMRT phantom using presage/optical-CT, Med Phys. 2009 Jul;36(7):3371-7.
56. Clift,C, Thomas A, Adamovics J, Chang Z, Das I, Oldham M, “Toward acquiring comprehensive radiosurgery field commissioning data using the Presage/optical-CT 3D dosimetry system”, Phys. Med. Biol. Mar 7;55(5):1279-93, 2010.
57. Brady S, Brown WB, Clift CG, Yoo S, Oldham M, Investigation into the feasibility of using PRESAGETM/ optical-CT 3-D dosimetry for the verification of gating treatments, Phys. Med. Biol. 55(8):2187-201, 2010 58. Low D, Dempsey J, Dong L, Moran J, Oldham M, Dosimetry Tools and Techniques for IMRT, AAPM Task Group TG120, Med Phys. 2011 Mar;38(3):1313-38
59. Baldock C, Deene Y De, Simon J Doran, G Ibbott, A I Jirasek, M Lepage, Kim McAuley, M Oldham and L J Schreiner, Topical Review: Polymer gel dosimetry, Phys. Med. Biol., Mar 7;55(5):R1-63, 2010
60. Thomas A, Bowsher J, Roper J, Oliver T, Dewhirst M, Oldham M, A comprehensive method for optical- emission computed tomography, Phys. Med. Biol, 55 pp3947-3957, 2010
61. Thomas A, Pierquet M, Jordan K, Oldham M., A method to correct for spectral artifacts in optical-CT dosimetry. Phys Med Biol. 2011 Jun 7;56(11):3403-16
62. Farfan E, Stanley S, Holmes C, Lennox K, Oldham M, Clift C, Thomas A, Adamovics J, Locating radiation hazards and sources within contaminated areas by implementing a reverse ray-tracing technique in the Radball Technology, Health Physics Journal, In Press, Dec 2011
63. Thomas A, Newton J, Oldham M, A method to correct for stray light in telecentric optical-CT imaging of radiochromic dosimeters. Phys Med Biol. 2011 Jul 21;56(14):4433-51.
64. Thomas A, Newton J, Adamovics J, Oldham M, Commissioning and benchmarking a 3D dosimetry system for clinical use. Med Phys. 2011 Aug;38(8):4846-57
65. Newton J, Oldham M, Thomas A, Yifan L, Adamovics J, Kirsch D, Das S, Commissioning a small-field biological irradiator using point, 2D and 3D dosimetry techniques., Medical Physics, Dec 2011 (In Press)
66. Oldham M, Thomas A, O‟Daniel J, Juang T, Ibbott J, Adamovics J, Kirkpatrick J, “A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation”, IJROBP, Dec 2011 (In Press)
Manuscripts In Press or under review
2. Non-referred publications: (Non-referred publications refer to those that do not routinely use a system of critical review prior to publications; such articles are often solicited by the publisher.) Abstracts.
1. Eduardo B. Farfán, Trevor Q. Foley, G. Timothy Jannik, John R. Gordon, Larry J. Harpring, Ronald Blessing, Steven J. Stanley, Chris J. Holmes, Mark Oldham, and John Adamovic, TESTING OF THE RADBALL TECHNOLOGY AT SAVANNAH RIVER NATIONAL LABORATORY, Savannah River Nuclear Solutions, SRNL- STI-2009-00808, 2/10/2010
3. Chapters in books:
Oldham M, “Radiation sensitive Films and Gels”, book chapter in “Radiotherapy Physics: Theory and practice”, Editors Rosenwald, Nahum and Mayles, 2007, ISBN 0-7503-0860-5
4. Books: (Indicate authors or editor.)
5. Non-authored publications: (Faculty member formally acknowledged in the publication for her/his contributions.)
6. Other: a. Published scientific reviews
b. Select Abstracts
1. Oldham M and Edge RJ “Determination of the gravitational constant using a power storage reservoir” Geophysical Journal - Oxford, 1988, Vol.92, No.3, p.537 (1988) 2. Edge R J and Oldham M “The investigations of gravity variations near a pumped storage reservoir in North Wales”, Gravity, Gradiometry and Gravimetry, Symposium No. 103, (Edited by R. Rummel and R.J. Hipkin), New York, Springer Verlag, p21-30. (1990) 3. Oldham M, and Webb S “Clinical implementation of Inverse Treatment Planning”, British Journal of Radiology 66, p162. (1993) 4. Webb S, and Oldham M “Optimisation of Conformal 3D Dose Distributions Created by a Multileaf Collimator; Options Including Modelling of Biological Response”, Joint British Institute of Radiology and Institute of Physical Science in Medicine meeting Book. (1993) 5. Oldham M and Webb S “Inverse Planning and the Optimisation of Radiotherapy Plans by Simulated Annealing Incorporating Dual Weighting.” Proc. of the XIth ICCR (Int. Conf. on the use of Computers in Radiation Therapy), (Eds. Hounsell A R, Wilkinson J M, and Williams P C), Manchester, p60-61. (1994) 6. Oldham M, and Webb S “The Optimisation and Inherrent Limitations of 3D Conformal Radiotherapy Treatment Plans of the Prostate.”, Radiotherapy and Oncology, 37 (suppl 1), pS14. (1995) 7. Oldham M, Neal A J, Webb S “Custom Optimisation of Wedge Angles in Prostate Radiotherapy”, Radiotherapy and Oncology, 37 (suppl 1), pS60. (1995) 8. Oldham M, Neal A J, and Webb S “A Comparison of ‘Forward Planning’ with Optimised Inverse Planning”, Radiotherapy and Oncology, 37 (suppl 1), pS4. (1995) 9. Neal A J, Oldham M, and Dearnaley D “Comparative Evaluation of Coplanar Techniques for Prostate Conformal radiotherapy”, ECC08 meeting, Paris Nov. (1995) 10. Neal A J, Oldham M, and Dearnaley D “Evaluation of Coplanar Beam Techniques for Prostate Conformal Radiotherapy”, British Journal of Cancer, 72 (supp. 25) p14. (1995) 11. Oldham M and Webb S “Optimisation by Fast-Simulated-Annealing of 3D Conformal Radiotherapy Treatment Plans of the Prostate and Theoretical Limits of Improvement”, Proc of Röntgen Centenary Congress, Birmingham, U.K., p474. (1995) 12. Oldham M, A J Neal and S Webb “A Comparison of Conventional ‘Forward Planning’ with Inverse Planning for 3D Conformal Radiotherapy of the Prostate”, Proc of Rontgen Centenary Congress, Birmingham, U.K., p229 (1995) 13. Neal A J, M Oldham, and D Dearnaley “Comparison of Treatment Techniques for Conformal Radiotherapy of the Prostate Using Dose-Volume-Histograms”, Proc of Rontgen Centenary Congress, Birmingham, U.K., p111 (1995) 14. Webb S and Oldham M “Advanced methods for delivering conformal therapy and dose planning techniques” Proc of 5th International Conference on Applications of Physics in Medicine and Biology: 9th AIFB Congress, EFOMP Medical Physics „96, Eutech 96, Trieste, Italy, September, Physica Medica Eutech. (1996) 15. Baustert I, Oldham M, Smith TAR, Webb S, Leach MO “T2 images used for isodose plots in conformal static tomotherapy” 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Vancouver, April. (1997) 16. Baustert I, Oldham M, Smith TAR, Webb S, Leach MO “Evaluation of radiation dose distribution from polyacrylamide gels using data from MR images”, 7th Annual UK NMR Symposium, London. (1997) 17. Baustert I, Oldham M, Smith TAR, Webb S, Leach MO “Error Evaluation in Magnetic Resonance Imaging Dosimetry” , 5th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Vancouver, April. (1997) 18. Rowbottom C, Oldham M, Webb S “Optimisation of beam orientations in Radiotherapy Treatment Planning”, Radiology 1997, Annual Conference of the British Institute of Radiology, May, Birmingham, p6. (1997) 19. Oldham M, Baustert I, Smith T, Webb S, Leach M “BANG gel dosimetry and the verification of Intensity Modulated radiotherapy plans”, Radiology 1997, Annual Conference of the British Institute of Radiology, May, Birmingham, p99. (1997) 20. Oldham M and Webb S “Film verification of a 9 field intensity modulated plan”, Radiology 1997, Annual Conference of the British Institute of Radiology, May, Birmingham, p17 (1997) 21. Oldham M and Webb S “IMRT delivery with the NOMOS MIMiC: Part II - verification using film and BANG gel dosimetry”, Proceedings of the IPEM meeting „Intensity Modulated Radiation Therapy: A Clinical Perspective‟, London, June, p19-20. (1997) 22. Webb S and Oldham M, “IMRT delivery with the NOMOS MIMiC: Part I - modelling treatment delivery”, Proceedings of the IPEM meeting „Intensity Modulated Radiation Therapy: A Clinical Perspective‟, London, June, p17-18 (1997) 23. Oldham M, “The impact of computer optimisation on treatment planning”, Proceedings of the World Congress on Medical Physics and Biomedical Engineering, Vol 35, Supp Part 2, Nice, Sept 14-19, p919 (1997) 24. Hepworth SJ, Doran JS Morton EJ, McJury M, Oldham M Dose mapping of inhomogeneities positioned in radiosensitive polymer gels, Michigan May (1998) 25. Khoo KS, Oldham M, Bedford J, Rowbottom C, Brada M, Webb S, “Comparison of an intensity-modulated tomotherapy (IMRT) approach with conventional non-coplanar external beam stereotactic guided conformal therapy for brain tunours” ESTRO Edinburgh (1998) 26. Oldham M, Khoo V, Bedford J, Rowbottom C, Webb S “A comparison of optimised conventional radiotherapy with tomotherapy in the brain” AAPM meeting, San Antonio. Med. Phys. 25 No 7 pA118 (1998)
27. Oldham M, McJury M, Baustert IB, Webb S, Leach MO “Improving calibration accuracy in gel-dosimetry” AAPM meeting San Antonio, Med. Phys. October (1998) 28. Webb S and Oldham M, “Implementation of IMRT with the NOMOS MIMiC” ESTRO conference Edinburgh (1998) 29. Oldham M, Sapareto S, Yan D, Wong J, “Optimising clinical outcome in radiation therapy” ESTRO Physics meeting, Gottingen, Germany April (1999) 30. McJury M, Oldham M, Leach MO, and Webb S “Dynamics of polymerisation in polyacrylamide gel (PAG) dosimeters: (I) Ageing and long-term stability” Brit Inst Radiol meeting „Radiology 1999‟, Birmingham UK May (1999) 31. McJury M, Tapper P, Cosgrove V, Murphy PS, Griffin S, Leach MO, Webb S, Oldham M “Experimental Dosimetry around a high dose rate 192Ir source using a polyacrylamide-gel dosimeter” Brit Inst Radiol meeting „Radiology 1999‟, Birmingham UK May (1999) 32. Wong JW, Oldham M, Worstell W, Dolinsky S, Zavarzin V “A portable PET camera for tumour perfusion imaging” Medical Physics 26(6) p1120, 1999. 33. Oldham M, Sapareto SA, Allen J, Kim LH, Wong JW “15O photon activation using an Elekta SL25” Medical Physics 26(6) p1120, 1999. 34. Oldham M, McJury M, Murphy PS, Cosgrove V, Leach MO, and Webb S “Ageing and stability in polymer gels”, Proc. Of the 1st Int. Workshop on Rad. Therapy Gel Dosimetry, Lexington Kentucky. (1999) 35. Armour E, Wong J, Oldham M, Gavin P, Worstell W, Sutleif S Tumour hypoxia imaging with washout of 15-O, Rad. Res. Soc. 47th Annual meeting, (2000) 36. Oldham M, J Siewerdsen and D A Jaffray An initial investigation of Optical CT and MR scanning of gel dosimeters, Proc of 11th ICCR Heidelberg (2000) 37. Oldham M, Siewerdsen J, Jaffray DA, “An investigation comparing optical-CT with MR scanning for gel dosimetry” Proc of the World Congress on Medical Physics, Chicago, USA July, (2000). 38. Oldham M, DA Jaffray, K Zakalik, P Chen, J Wong, “Rind-Therapy: A New Approach to the Treatment of Larger Brain Tumours” Proc of the World Congress on Medical Physics, Chicago, USA July, (2000). 39. Oldham M, C.G.Rowbottom, D.A.Jaffray, “Radiosurgery with a motorized micro-multi-leaf collimator: initial experiences in planning and commissioning” Medical Physics, WE-CC-EXH C-37, July 2001 40. Oldham M, Siewerdsen JH, Jaffray DA “Optical scatter measurements in BANGTM and FX gel” 2nd International Conference on Radiotherapy Gel Dosimetry, Brisbane, November, 2001 41. Oldham M, Siewerdsen JH, Jaffray DA “Optical CT scanning: from 2D to 3D while meeting the RTAP criteria” 2nd International Conference on Radiotherapy Gel Dosimetry, Brisbane, November, 2001 42. Oldham M, “Gel Dosimetry – a wider perspective”, invited seminar, 2nd International Conference on Radiotherapy Gel Dosimetry, Brisbane, November, 2001 43. Wong, J., Jaffray, D. A., Siewerdsen, J. H., Oldham, M., Laub, W, and Armour, E "An image guided small animal conformal radiation research platform", 49th Annual Meeting of the Radiation Research Society, p312-313, Reno, Nevada 2002 44. Letourneau DL, Jaffray DL, Oldham M, Sharpe MB, Wong J, “Clinical implementation of a kV imager for set up error verification in radiotherapy”, Med Phys (29) No 6, p1243 June 2002 45. Oldham M, “The role of gel dosimetry at William Beaumont Hospital”, invited speaker CCPM/COMP Symposium on Gel Dosimetry, (AAPM) Montreal, June 2002 46. Oldham M, Letourneau DL, Siewerdsen JH, Gluckman G, Jaffray DA “Achieving and utilizing the 3rd dimension in optical gel dosimetry”, Med Phys (29) No 6, p1370 June 2002 47. Oldham M, “Light transport in optical-CT gel-dosimetry: optical Monte-Carlo modelling”, Med Phys (29) No 6, p1370 June 2002 48. Gulam M, Letourneau D, Oldham M, Wong J “Use of a „virtual cross-hair‟ to calibrate a kV imaging system for online radiographic set-up verification” Med Phys, 30 (6) p1338, 2003 49. Oldham M, Kim LH, “A study of geometrical and reconstruction artifacts in 3D gel-dosimetry utilizing optical- CT”, Med Phys 30(6) p1426, 2003 50. Oldham M, D Letourneau, L Watt, J Wong, “Application of on-line imaging to improve set-up in stereotactic therapy.” Med Phys 30(6) p1471, 2003 51. Ghilezan M, Lockman DL, Jaffray DA, Oldham M, Vicini F, Matter R, Wong J, Martinez AA “Can the anatomical location of the prostatic neurovascular bundle and the penile bulb be reliably determined for the purpose of on-line nerve sparing image-guided radiation therapy for prostate cancer”, IJROBP, Vol 57 (2), ppS332, 2003 52. Letourneau DL, Oldham M, Watt L, Gulam M “Implementation of an on-board kV imaging system for clinical applications”, ASTRO Oral presentation Oct 2003 53. Oldham M, D Letourneau, L Watt, PY Chen, AA Martinez, J Wong, “On-line Volumetric CT Guided Radiation Therapy.” IJROBP, Vol 57 (2), ppS184, 2003 54. L Kim, G Gluckman, M Oldham Initial Application of 3D Gel-Dosimetry for the Clinical Verification of Complex Dose Distributions, Med Phys, 31 (6) p1698, 2004 55. D Gultekin*, T Raidy, M Oldham, Radiation Dose and Temperature Dependence of Metabolite Signals in Proton Magnetic Resonance Imaging and Spectroscopy, Med Phys 31 (6) p1691, 2004 56. M Oldham, Novel Dosimetry Systems for IMRT and Complex Radiation Treatments, Medical Physics, 31 (6) p1689, 2004 57. M Oldham, G Gluckman, L Kim, „3D verification of a prostate IMRT treatment by polymer gel-dosimetry and optical-CT scanning‟, J. Phys.: Conf. Ser. 3 293-296, 2004 58. Baydush A, Godfrey D, Oldham M, Dobbins J, „Initial application of digital tomosynthesis with on-board imaging‟, Proceedings of SPIE Vol. 5745, Physics of Medical Imaging, San Diego, Edited by M.J.Flynn, pp1300-1305, 2005 59. M Oldham, L Kim, „Optical-CT imaging of complex 3D dose distributions‟, Proceedings of SPIE Vol. 5745, Physics of Medical Imaging, San Diego, Edited by M.J.Flynn, pp138-146, 2005 60. Z. Wang, F-F. Yin, L. Marks, T. Raidy, K. Kelly, M. Oldham, S. Das, S. Zhou, M. Kasibhatla, and C. Willett, „Reduction of Normal Organ Motion by Combined Cardiac/Respiratory Gating‟, Med Phys 32, p1926, 2005. 61. Guo P, Appleby A, Oldham M, „The study of the dosimetric properties of „RadGel‟, a new dosimeter for three-dimensional gel dosimetry‟ Med Phys, 32, p2009, 2005 62. Raj, KA; Guo, P 1; Jones, E; Marks, L; Raidy, T; Oldham, M, „Intrafraction Organ Motion of the Normal Cervix‟, IJROBP, Vol 63 S1, PPS220, 2005 63. Guo, P 1; Adamovics, J 2; Oldham, M 1. „PRESAGE - a promising new material for 3D dosimetry‟, IJROBP, Vol 63 S1, ppS206, 2005
64. Z. Wang, F-F. Yin, T. Raidy, K. Kelly, M. Oldham, S. Das, S. Zhou, L. Marks, M. Kasibhatla, and C. Willett, „Quantification of Normal Organ Motion due to the Respiratory and Cardiac Cycles‟ poster presentation AAPM 2005. 65. Guo P, Adamovics J, Oldham M, „Characterization of a new 3D dosimetric material ''PRESAGE'‟, Med Phys 32, p2136, 2005
66. Godfrey D, Oldham M, Dobbins JT, Yin FF, Online digital tomosynthesis: A novel technique for improving target localization in radiation therapy, IJROBP, Vol 63(S1), ppS556, 2005
67. K Raj, P Guo*, T Raidy, M Oldham, „TOMAS, a Tool for Organ Motion AnalysiS Submission Number‟, Med Phys 32, p2136, 2005 68. M Oldham, ‘Status of 3D dosimetry techniques‟, Invited review talk at AAPM, Seattle, 2005 69. M Oldham, T Oliver, M Dewhirst, „Optical imaging of tumor microvasculature in 3D. Med Phys 32, p2134, 2005 70. Godfrey D, Oldham M, Yin F, Dobbins J, „Digital tomosynthesis for radiation therapy‟, poster presentation AAPM, 2005 71. Oldham,M, Wang Y, Vujaskovic,Z, Dewhirst M, “Optical-Computed-and Emmission Tomography: a new imaging modality for cancer research, Radiotherapy and Oncology, Vol 78, S1, pS55-S56, March 2006 72. D Low, J Dempsey, P Jursinic, and M Oldham WE-E-T-6E-01: Multidimensional Dosimetry Without Film Processors Med. Phys. 32 2148 (2005) 73. Oldham M, Oliver T, Dewhirst M, A Novel Method of Imaging Unperturbed Tumor Vasculature in 3D, IJROBP, Vol 63, S1, ppS134 2005 74. Kasibhalta M, S. Yoo, F. Yin, D. Godfrey, M. Oldham, S.K. Das, Assessment of Setup Accuracy for Prostate Radiotherapy using On-board Imaging and Cone Beam Computed Tomography, IJROBP, Vol 3 S1, pp S535, 2005 75. P. Y. Guo, J. A. Adamovics, and M. Oldham Characterization of a new radiochromic three-dimensional dosimeter Med. Phys. 33 1338 (2006) 76. A Manzoor, P Guo, J Adamovics, and M Oldham SU-FF-T-89: An Exploration of New Formulations for PRESAGETM 3D Dosimetry Med. Phys. 33 2069 (2006) 77. M Goss, P Guo, F Yin, and M Oldham SU-FF-T-219: Evaluation of a Practical and Low Cost Gafchromic Film/flat-Bed Scanner Combination for Planar Dosimetry Med. Phys. 33 2098 (2006) 78. P Guo and M Oldham SU-FF-T-230: Evaluation of the Performance of An Optical CT Scanner Med. Phys. 33 2101 (2006) 79. P Guo, J Adamovics, and M Oldham TU-C-224C-02: A Practical and Accurate 3D Dosimetry System for Radiation Therapy Med. Phys. 33 2193 (2006) 80. H Sakhalkar, Y Wang, T Oliver, M Dewhirst, and M Oldham WE-D-330A-01: 3D Optical Imaging of Tumor Microvasculature and Viable Cell Distribution Med. Phys. 33 2239 (2006)
81. M Oldham, H Sakhalkar, T Oliver, and M Dewhirst WE-D-330A-02: Optical-Computed-and Emmission Tomography: Applications in Cancer Research Med. Phys. 33 2239 (2006)
82. D Godfrey, L Ren, H Yan, M Oldham, and F Yin TH-C-ValB-04: Evaluation of the Quality of 3D-3D Mutual Information (MI) Shared Between Reference and On-Board DTS Images Med. Phys. 33 2268 (2006) 83. D Godfrey, F Yin, Z Wang, S Yoo, M Oldham, and C Willett TH-C-ValB-05: Rapid Low-Dose 3D Image- Guided Treatment Verification of Sites Prone to Respiratory Motion Using Breath-Hold On-Board Digital Tomosynthesis (DTS) Med. Phys. 33 2268 (2006)
84. P Guo, J Adamovics and M Oldham, Investigation of the dosimetric characteristics of PRESAGETM, J. Phys.: Conf. Ser. 56, pp211-214, 2006 85. M Oldham, H Sakhalkar and P Guo, A dual-purpose CCD based micro-optical-CT scanning system, J. Phys.: Conf. Ser. 56, pp199-202, 2006 86. P Guo, J Adamovics and M Oldham, Quality assurance in 3D dosimetry by optical-CT, J. Phys.: Conf. Ser. 56, pp195-198, 2006 87. P Guo, J Adamovics and M Oldham Simple 3D validation experiments for PRESAGETM/optical-CT dosimetry, J. Phys.: Conf. Ser. 56, pp187-190, 2006 88. Oldham M, P Guo, J Adamovics, H Sakhalkar, Z Wang and Ff Yin, Towards four dimensional (4D) dosimetry for radiation-therapy, J. Phys.: Conf. Ser. 56, pp225-228, 2006 89. J Adamovics, P Guo, D Burgess, A Manzoor and M Oldham, PRESAGETM - Development and optimization studies of a 3D radiochromic plastic dosimeter–Part 2, J. Phys.: Conf. Ser. 56, pp176- 178, 2006
90. Oldham, M., Guo, P., Gluckman, G., Adamovics, J., IMRT verification using a radiochromic/optical-CT dosimetry system, J. Phys.: Conf. Ser. 56, pp221-224, 2006 91. J Pursley, GP Beyer, O Craciunescu, C Fraisse, J Carroll, and M Oldham SU-FF-T-98: Characterization of Buildup Effects in OneDosePlus MOSFET-Based Dosimeters Med. Phys. 34 2423 (2007)
92. M Goss and M Oldham SU-FF-T-208: Evaluation of a New Radiochromic Film/Flatbed Scanner System for Planar Clinical Dosimetry Med. Phys. 34 2449 (2007)
93. H Sakhalkar, P Guo, J Adamovics, and M Oldham WE-E-AUD-03: Characterization of a Novel, Fast, In- House, CCD-Based Optical-CT Scanner for 3D Dosimetry in Radiochromic Dosimeters Med. Phys. 34 2610 (2007)
94. GP Beyer, J Pursley, G Mann, E Espenhahn, C Fraisse, D Godfrey, and M Oldham WE-E-AUD-04: Radiation Characteristics and Hypo-Fractionation Dose Response for the DVS Implantable MOSFET Dosimeter Med. Phys. 34 2610 (2007) 95. M Oldham, D Sterling, H Sakhalkar, A Molineu, J Adamovics, and G Ibbott SU-GG-T-135: Evaluation of PRESAGE/optical-CT 3D Dosimetry for Commissioning a Linac for IMRT Med. Phys. 35 2757 (2008) 96. D Sterling, H Sakhalkar, and M Oldham SU-GG-T-153: Scaling the Prescription Dose: How Accurate Is the Varian Delivery System? Med. Phys. 35 2761 (2008) 97. B Taylor, J Boyd, M Kasibhatla, and M Oldham SU-GG-J-28: An Investigation of Intra and Inter-Fraction Motion in Cervical Cancer Patients Med. Phys. 35 2685 (2008) 98. S Brady, H Sakhalkar, J Maurer, S Yoo, J Adamovics, G Gluckman, and M Oldham TU-FF-A2-06: The Verification of Respiratory-Gated Radiation Treatments Using 3D Dosimetry Techniques Med. Phys. 35 2921 (2008) 99. H Sakhalkar, J Adamovics, G Gluckman, and M Oldham TU-D-AUD C-02: An Investigation of the Consistency and Robustness of the PRESAGE/optical-CT 3D Dosimetry System Med. Phys. 35 2903 (2008) 100. V Hosfeld, J Kirkpatrick, and M Oldham SU-GG-T-438: Rind Radiosurgery: Investigation of a Novel Radiation Therapy Technique for the Treatment of Intracranial Lesions Med. Phys. 35 2825 (2008) 101. M. Oldham, H. Sakhalkar, J. Adamovics, A. Molineu, G. Ibbott , The Feasibility of Comprehensive IMRT Verification using Novel 3D Dosimetry Techniques Compatible with the RPC Head and Neck Phantom, International Journal of Radiation Oncology * Biology * Physics, September 2008 (Vol. 72, ( 1), Page S145)
102. E Kim, J Bowsher, H Sakhalkar, M Dewhirst, and M Oldham TU-FF-A4-03: Improving the Accuracy of Optical-Emission-CT Imaging Through Application of a Non-Uniform Attenuation Correction Med. Phys. 35 2923 (2008)
103. H Sakhalkar, A Thomas, R McMahon, A Washington, J Adamovics, and M Oldham SU-FF-I-153: First Experience of High Resolution 3D Optical-CT Scanning of An Anthropomorphic, Leuco-Dye Doped, Radiochromic Plastic Dosimeter Med. Phys. 36 2470 (2009)
104. B Mader, A Cabrera, E Jones, and M Oldham SU-FF-J-103: Concepts for Normal Tissue Sparing with Patient-Specific Margins in IMRT Boost Treatments for Cervix Med. Phys. 36 2500 (2009)
105. A Thomas, C Clift, J O'Daniel, R McMahon, H Sakhalkar, W Brown, J Adamovics, A Washington, and M Oldham TU-E-304A-06: A 3D Solution for Advanced Photon Arc Therapy Quality Assurance Med. Phys. 36 2748 (2009)
106. W Brown, J Deasy, D Khullar, A Apte, A Thomas, and M Oldham SU-FF-T-482: Extension of An Informatics Architecture to Compare and Analyze 3D Dosimetric Data Med. Phys. 36 2634 (2009)
107. C Clift, A Thomas, A Washington, J Adamovics, I Das, and M OldhamTH-D-BRB-03: The Application of a Novel Three Dimensional Dosimetry System to the Acquisition of Commissioning Data of Small Photon Fields Med. Phys. 36 2810 (2009)
108. Farfán E, Foley T1, G. T Jannik, J, Harping L, Gordon JR, Blessing R, R. Coleman 1, S J. Stanley2, CJ. Holmes2, M Oldham3, J Adamovics4, RadBallTM Technology Testing in the Savannah River Site‟s Health Physics Instrument Calibration Laboratory, J Phys. 2010;250(1):12080
109. Farfán E, Foley T1, J. R. Coleman 1, G. T Jannik1, CJ. Holmes2, M Oldham3, J Adamovics4, and S J. Stanley2, RadBallTM Technology Testing and Modeling, J Phys. 2010;250(1):12081 110. L Stunja*, A Thomas, J Adamovics1, J Deasy2, M Oldham, A „quad-phantom‟ film dosimeter for use as a multi-planar verification tool for PRESAGE/optical-CT, J Phys. 2010;250(1):12097 111. J. R. Newton1, A. Thomas1, A. Appleby2, C. Marsden2, E.A. Christman2, J.G. Wolodzko2, M. Oldham1, Preliminary Investigation of the Dosimetric Properties of „RadGel‟, J Phys. 2010;250(1):12011
112. J. Newton, A. Thomas, G. Ibbott1, M. Oldham, Preliminary commissioning investigations with the DMOS-RPC optical-CT Scanner, J Phys. 2010;250(1):12078 113. Pierquet M, Thomas A, Adamovics J, Oldham M, An Investigation Into a new Re-useable 3D Radiochromic Dosimetry Material, PresageREU, J Phys. 2010 Jan 1;250(1): 12047 114. Pierquet M, Song H, Oldham M, On the Feasibility of Verification of 3D Dosimetry Near Brachytherapy Sources Using PRESAGE/Optical-CT, J Phys. 2010;250(1):12091
115. Oldham M, “ScanSim: A tool for simulating 3D Optical-CT imaging, J Phys. 2010;250(1):12064 116. Oldham M, Clift C, Thomas A, Farfan E1, Foley T1, Jannik T1, Adamovics J2, Holmes C3, Stanley S3, Initial experience Optical-CT scanning of RadBall Dosimeters, J Phys. 2010 Dec 7;250(1). pii: 012079 117. Grant RL, Crowder ML, Ibbott GS, Simon J, Frank RK, Rogers J, Loy HM, Adamovics J, Newton J, Oldham M, Stearns S, Wendt RE. Three-Dimensional Dosimetry of a Beta-Emitting Radionuclide Using PRESAGE Dosimeters., J Phys. 2010 Dec 7;250(1). pii: 012095.
118. A Thomas*, M Oldham, Fast, large field-of-view, telecentric optical-CT scanning system for 3D radiochromic dosimetry, J Phys. 2010 Jan 1;250(1):1-5. 119. Thomas A, Pierquet M, Oldham M, Achieving accurate radiochromic optical-CT imaging when using a polychromatic light source, J Phys. 2010;250(12045):210-214. 120. Li Zhao, Indra J.Das, Frank Zhao, Andrew Thomas, John Adamovics, and Mark Oldham, Determination of the dose depth distribution of proton beam using PRESAGETM dosimeter, J Phys. 2010;250(1):12035 121. Wang, A. Thomas, J. Newton, J Deasy2, G. Ibbott3, M. Oldham, Dose Verification of Stereotactic Radiosurgery Treatment for Trigeminal Neuralgia with Presage 3D Dosimetry System, J Phys. 2010 Dec 7;250(1). pii: 012058. 122. Thomas A, Bowsher J, Roper J, Oldham M, A Comprehensive Method for Optical - Emission Computed Tomography, Med. Phys. 37, 3406 (2010)
123. Song H, Oldham M, Yin FF, Is Distance-Dependent Energy Correction Needed for Dosimetric Measurements Surrounding Brachytherapy Sources?, Med. Phys. 37, 3269 (2010)
124. Oldham M, Thomas A, Schroeder T, Fontanella A, Dewhirst M, Imaging the Biological Structure and Characteristics of Model Tumors Using Optical Computed Transmission and Emission Tomography, Med. Phys. 37, 3405 (2010) 125. Pierquet M, Song H, Oldham M, 3D Dosimetric Verification of Ir-192 HDR Brachytherapy Source Irradiation, Med. Phys. 37, 3269 (2010)
126. M. Oldham, Memorial to Lester Skaggs, Med. Phys. 37, 3381 (2010)
127. Pursley J, Oldham M, Measurement of Dose to Pacemakers and Other Implantable Medical Devices, Med. Phys. 37, 3271 (2010)
128. A Thomas, J Newton, J Adamovics, and M Oldham, Commissioning and Benchmarking a 3D Dosimetry System for Clinical Use, Med. Phys. 38, 3817 (2011)
129. R Grant, G Ibbott, X Zhu, M Carroll, J Adamovics, M Oldham, and D Followill, Investigation of PRESAGE® Dosimeters for Proton Therapy, Med. Phys. 38, 3571 (2011)
130. F Yin, A Thomas, H Yan, I Vergalasova, J Adamovics, Q Wu, and M Oldham, A Patient Specific QA Protocol for Verification of 4D Dosimetry, Med. Phys. 38, 3508 (2011)
131. L Zhao, J Newton, J Adamovics, M Oldham, C Cheng, and I Das, Dosimetry for Small Irregular Proton Fields Using a New PRESAGE® Dosimeter, Med. Phys. 38, 3506 (2011)
132. A Thomas, J Newton, and M Oldham, A Method to Improve the Accuracy of Optical‐CT 3D Dosimetry by Correcting for Stray Light, Med. Phys. 38, 3517 (2011)
133. M Oldham, G Ibbott, B Mijnheer, and T Zhu, How Should We Verify Complex Radiation Therapy Treatments ?, Med. Phys. 38, 3766 (2011)
134. J Newton, M Oldham, Y Li, J Adamovics, and S Das, Commissioning a Small Animal Irradiator Using 2D and 3D Dosimetry Techniques, Med. Phys. 38, 3734 (2011)
135. M Oldham and A Thomas, A Method to Determine Measured Dose‐Volume‐Histograms (DVH) in Patient from 3D Dose Measurement in Phantom, Med. Phys. 38, 3753 (2011)
Consultant appointments: (Include US government, state, private organizations, etc.)
SBIR consultant for Dosimetrics Inc, NJ “ Development of the Radgel 3D dosimetry material‟, Jan 2010 + SBIR consultant for Alan Appleby PhD, 2003, New Radiochromic 3D dosimeters SBIR consultant for Marek Maryanski PhD, 2004
Professional awards and special recognitions:
1996 Performance-Related Merit Award from the Institute of Cancer Research, UK. 1997 Best poster at the Institute of Cancer Research Annual Conference, UK 1997 The Royal Society, Travel Award 2002 Farrington-Daniels Award: Best paper in Journal of Medical Physics on Radiation Dosimetry 2002 Didactic Instructor of the Year, Radiation Physics, William Beaumont Hospital, School of Rad Therapy 2007 AAPM-IPEM Travel Award for 3 weeks lecture tour to Radiation Oncology centers in the UK 2008 Senior Author on paper shortlisted for the Roberts Prize, from J Phys. Med. Biol. (Kim et al 2009) 2008 Senior author on paper selected for the Physics in Medicine and Biology Highlights 2008 special selection. PMB Highlights 2008. Phys. Med. Biol. 53(19) pp5371-5383, 2008 2009 Director‟s Award for exemplary service to the Duke University Medical Physics Program, in the capacity as Director of the Radiation Therapy Track (2005-present). 2010 Fellow of the AAPM 2010 Senior author on paper selected for Editors Choice and the Physics in Medicine and Biology Highlights 2010 special selection. PMB Highlights 2010. Phys. Med. Biol. 55 pp3947-3957, 2010 2011 Directors Award for Excellence in Mentoring 2010-2011, Duke Medical Physics Graduate Program. 2011 Directors Award for Exemplary Service 2010-2011, Duke Medical Physics Graduate Program.
Organizations and participation: (Offices held, committee assignments, etc.)
Professional Activities and Memberships 1997+ Corporate Member of the Institute Of Physics and Engineering in Medicine (MIPEM) 1997+ Member of the Institute of Physics (CPhys MInstP) 1997+ Full Member of the American Association of Physicists in Medicine (AAPM) 1998+ Referee for the journals Medical Physics, Phys. Med. Biol., Rad Onc, IJROBP, J Biomed Optics 2000-5 Member of Great Lakes Chapter of AAPM 2000+ Associate Editor for Medical Physics. 2004+ Abstract reviewer for AAPM annual meeting 2005+ Member of Duke Comprehensive Cancer Center 2005 Ad-hoc reviewer for the NIH, RTB study section 2006+ International Advisory Board Member, Journal of Physics in Medicine and Biology (PMB) 2006-8 Member of the Therapy Physics Committee (steering committee of AAPM scientific activities) 2006 Member: International Scientific Committee for 4th Int. Conference on Radiotherapy Gel Dosimetry, Sherbrook, CA 2008+ Abstract reviewer and moderator for ASTRO annual meeting 2008 Member: International Scientific Committee for 5th Int. Conference on Radiotherapy Gel Dosimetry, Crete 2010 Chair, 6th International Conference on 3D Radiation Dosimetry, Hilton Head, SC
Professional Activities for the American Association of Physicists in Medicine (AAPM): 2006-2008 [TPC] Therapy Physics Committee – oversees AAPM scientific activities. 2006-2012 [RDSC] Radiation Dosimetry & Treatment Planning Subcommittee 2008-2011 [WGRD] Work Group on Radiation Dosimetry 2005+ [TG113] Task Group No. 113 Physics Practice Standards for Clinical Trials 2005+ [TG120] Task Group No. 120 Writing group on IMRT Metrology 2007+ [TG131] Task Group No. 131 Medical Physics Training in Developing Countries in the Region 2007+ [TG155] Task Group No. 155 Small Fields and Non-Equilibrium Condition Photon Beam Dosimetry 2008+ [TG166] Task Group No. 166 Use and QA of biologically-related models for treatment planning 2007-2009 [WGFRF] Working Group on Federal Research Funding 2007-2009 [WGNRI] Working Group on New Research Initiatives 2010+ [WGDRD] Working Group on the Development of a Research Database 2011 Chair of a special symposium at annual AAPM mtg, „How should we verify complex RT treatments? 2012-2014 Member (at Large) of the Board of Directors, AAPM
Annual Teaching Responsibilities at Duke University Medical Center: 2005+ Introduction to Radiation Therapy Physics, Medical Physics Graduate Program, MP220, 3 c.h. 2004-2007 Biophotonics Instrumentation, Biomedical Eng Undergrad Program, BME265 - Project Instructor 2005+ Seminars in Medical Physics, MP251, weekly seminar course for MS/PhD students 2005+ Director of the RadOnc Track for the Duke Medical Physics Graduate Program
Teaching responsibilities including continuing education: (also see following Table) 1995-1998 Lecturer in Radiation Physics, Royal Marsden Hospital, Sutton, UK 1995-1998 PhD supervisor, and external PhD examiner for the University of London, UK. 2002-2003 IMRT for prostate cancer, William Beaumont Hospital IMRT course. 2004-2006 Lectured in Radiation Physics to Residents at Duke University 2009-2011 Teaching lectures at RSNA „Imaging in clinical trials‟
Trainees (since 2005 at Duke)
Areas of research interests (basic and applied) – list:
Clinical: Quality assurance in radiation therapy. In particular, to develop 3D dosimetry techniques that enable a more comprehensive verification of radiation treatments than is possible with existing systems. We have developed a state-of- art 3D dosimetry system at Duke with funding from the NIH. The main phase of research and development was completed in Jan 2011, and efforts have now shifted to application to clinical challenges and the verification of complex treatment techniques. We have publications and active collaborations in several direction including (main collaborators in brackets), Rapid-arc (Dr O‟Daniel), IMRT (Dr Das), gating (Dr F Yin and Dr S Yoo), radiosurgery (Dr Z Wang), small field dosimetry (Dr Z Chang), and brachytherapy (Dr Craciunescu, and Dr Song).
Basic Science: The development of novel high resolution 3D optical imaging techniques for studying vasculature, gene expression, hypoxia, and mechanisms of metastatic spread. We have built an optical-CT/ECT system which, in combination with bulk tissue optical-clearing techniques, can yield 50micron isotropic resolution of absorbing or fluorescing bio-markers in unsectioned tissue samples. We have published 5 papers with our main collaborator (Dr Mark Dewhirst, and Dr Tim Oliver (cell biology)) outlining all key aspects of the technique. Two of these papers were selected for the annual journal „highlights‟ selection of top papers from the journal of Physics in Medicine and Biology.
Further details can be found on the Labs home page Duke 3D Dosimetry and Optical Bio-imaging Lab
External support – gifts, grants, and contracts: Approximate PI %Effort Purpose Amount Duration a. Past:
PI %Effort Purpose Amount Duration Oldham 50 Accurate High Resolution 3D Dosimetry $952,000 2003-2007 CA100835 Oldham, 3D Dosimetry for Radiation Therapy N/A $83,367 2001-2002 WBH Grant Oldham 3D gel dosimetry system for clinical verification of N/A $78,310 2002-2003 WBH Grant conformal radiation therapy Oldham The Application of Gel Dosimetry to the Verification N/A 1997-2000 EPSRC Grant, UK Of Intensity Modulated Radiotherapy
Oldham A pilot evaluation study for the RadBall 3D 1 $37,935 2010 SRNL subcontract dosimetery system
Optical-CT, micro-MRI, MR Microscopy for 3D $10,000 Oldham (co-I) N/A Imaging 2006-2007
b. Present:
PI %Effort Purpose Amount Duration
Oldham 40 Accurate High Resolution 3D Dosimetry $1,435,980 2008-2012 CA100835
c. Pending:
Clinical activity – type of practice and estimate of time commitment:
Current: Typically ~50% clinical coverage. Lead physicist for the installation and commissioning of the new machine at Maria Parham Hospital (MPH) in 2008, and clinical start of IMRT. I continue to be the senior physicist covering MPH with typical coverage 2 days per week. I presently do IMRT planning, chart checking, and all types of QA (IMRT, monthly, annual etc). I also have a late period of physics coverage every week at Duke, and occasional coverage at Raleigh, Durham Regional and the VA. In addition, I am actively involved in improving the clinical quality assurance capabilities at Duke through the 3D dosimetry program. Since completing the commissioning of the DLOS 3D dosimetry in January 2011, we are applying this unique tool to several clinical tasks at Duke (Table I of personal statement).