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Mitochondrial ABC Transporters Vxpx Cargo-Targeting to Cilium Alpha

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Mitochondrial ABC Transporters Vxpx Cargo-Targeting to Cilium Alpha PA2GF PA2G5PA2GD PA21BPA2GEPA2GXPA2G3 Acyl chainAcyl chainremodelling remodelling of PI of PG Acyl chain remodelling of PS PA24C AcylAcyl chain chain remodelling remodelling of PCof PE GABA A receptor activation Neurotransmitter receptors and postsynaptic signal transmission GBRA2 GBRB3GBRA6GBRA5 PA2GA GBRA1GBRG2GBRB2GBRB1 GBRT GBRG3GBRA4GBRA3 PA24B Ligand-gated ion channel transport Acyl-CoA:dihydroxyacetonephosphateacyltransferase PPBI Hydrolysis of LPC Hydrolysis ofSynthesis LPE of PA LA Post-translational modification: synthesis of GPI-anchored proteins Catecholamine biosynthesis Plasmalogen biosynthesis GABAGBRR3 AGBRR2 (rho) receptor activation RNA Polymerase III Transcription Termination GBRR1 Creatine metabolism RNA Polymerase III AbortivePNMT AndDDC Retractive Initiation ReuptakeS6A11 of GABA PPBT DigestionPPBN S6A12SC6A7 Interaction between L1 and Ankyrins GLRA1 SC6A1 S6A13 SerotoninSodium/myo-inositol andInositol melatonin transporters cotransporter biosynthesis 2 GLRA2 KCRM FOLR2 KCNQ2 5HT3E5HT3D SC6A3 Astrocytic Glutamate-Glutamine Uptake And Metabolism 5HT3B EAA1 5HT3A5HT3C Na+/Cl- dependent neurotransmitter transportersDopamine clearance from the synaptic cleft SCN8AEAA2 Methylation of TransportINMTMeSeH forof inorganicexcretionSCNAASCN3ASCN2A cations/anions and amino acids/oligopeptidesGlycosyltransferase-likeO-linked glycosylation protein LARGE1 SC6A5SC6A9S6A15 SCN9ASCN4ASCN1ASCNBA SC6A6 SCN7ASCN5A Insulin effects increased synthesis of Xylulose-5-Phosphate SC6A2 TPH1 Potassium transport channels MOT2 Glutamine synthetaseCAC1I KCNJ1 Amino acid transport across the plasma membrane TKT EAA3 PRIO CAC1HCAC1G Proton-coupled monocarboxylate transport Glutamate Neurotransmitter Release Cycle Phase 3 - rapid repolarisationKCNQ1 Choline catabolism KCND3 NCAM1CAC1S interactions KCNH2 CarnitineBODG synthesis Voltage gated Potassium channels BHMT1 Reversal of alkylation damageFTOPhase by 1 DNA - inactivation dioxygenases of fast Na+ channels mRNA Editing:ABC3A C to U ConversionMethylenetetrahydrofolate dehydrogenase KCNE1 PAOX EBP S19A1 OAT PAOs oxidise polyamines to amines FOLH1 CAC1FCA2D1 Leukotriene receptors ADH1B ALDH2FADS2 6PGD NALD2 Signaling by plasma membrane FGFR1 fusions Ethanol oxidation ADH7AL1B1 PA24A Arachidonic acid metabolism ADHXADH6 ALKBH3 mediated reversal of alkylation damage VMAT2 tRNA processing in the nucleus Voltage-gated potassiumKCNA1 channel subunit beta-1 ALKB3 Formation of the Editosome 1-acylglycerol-3-phosphate O-acyltransferase alpha DDX1 Phase 2 - plateau phase Interconversion of polyamines KCNA3 ELOV5 MOT4MOT1 KCNA5 Linoleic acid (LA)ELOV1 metabolism BHMT2 Pyruvate metabolism Citric acid cycle (TCA cycle) KCNA4 ELOV2ELOV3 Amino acid synthesis and interconversion (transamination) Orexin and neuropeptides FF and QRFP bind to their respective receptors CLTR2 MDHM LT4R2LT4R1 GP183 CholesterolCholesterol biosynthesisbiosynthesis viavia lathosteroldesmosterolSerotoninSerotonin clearance NeurotransmitterSC6A4 from the Release synaptic Cycle cleft MetabolismXCT of folate and pterines Phase 0 - rapid depolarisation Synthesis of PIPs at the ER membrane CLTR1 GPR39 Pentose phosphate pathway (hexose monophosphate shunt) Acyl chain remodeling of CL FAAH1 GPR35 mRNA decay by 3' to 5' exoribonuclease DCPS Fatty-acid amide hydrolase 2 Metabolism of serotoninMitochondrial ABC transporters LGUL alpha-linolenic acid (ALA) metabolism ABCB6 PCFT FGFR1 Sulfur amino acid metabolism SGK3WNK2ASIC3 PI4KA QRFPR Hydroxycarboxylic acid-binding receptors SCNNBWNK1 NPFF2OX2R P2RY6P2Y10LPAR6GPR4GPR17P2Y receptors Glutathione synthesis and recycling SCNNASCNNGWNK3ASIC1 G6PC LPAR4 GP132 Class A/1 (Rhodopsin-like receptors) Gamma-glutamylcysteine synthetase CLCN3SGK2ANO1 ASNS F16P1G6PT1 NPFF1OX1RPLD2 ADH4ADH1G SAT1 Cell-extracellularMDHC matrix interactions Signaling by activated point mutants of FGFR1 HCAR2 LDHB Dopamine Neurotransmitter Release Cycle GCKR ADH1A LDHA Eicosanoid ligand-bindingLysosphingolipid receptors and LPA receptors ULK2GP139STK39CBX7NEK4 SDHA t(4;14) translocations of FGFR3 SignalingFGFR3 by mutantactivated receptor point mutants activation of FGFR3 P2RY1 AMDRAD54PAR12 Degradation of GABA ACM1ACM5 S22A9MYT1FUT9ERGDCLK2FUT7KPYR Synthesis of PG P2RY4P2Y14GPR55MTR1AMTR1B STK36SSH2TRYG1NEK5ANKK1ABHGA Norepinephrine Neurotransmitter Release Cycle GABT FGFR3b ligand binding and activation FGFR3cFGFR2c ligand ligand binding bindingHGFA and and activation activation HCAR1 PPM1DMRGX2SIK2 Voltage-gated N-type calcium channel alpha-1B subunit/Amyloid beta A4 precursor protein-binding family A member 1 FGFR1c Downstreamligand binding signaling and activation of activated FGFR1 LPAR3 GPR18CNR1SUCR1 HCAR3 ORAI3COQ8BMAST1ATX2CBPA1FCGRN ILK BRS3 LPAR5LPAR2 CNR2 B2LA1NR1I3TRYDTIE1 Synthesis of very long-chain fatty acyl-CoAs S40A1 SSDH FGFRL1 modulationFGFR3 of FGFR1 signaling GRM1 MTLRNMBR LPAR1S1PR2 GBRG1SENP7ABC3GNUAK2PIM2BMP6CDKL1 NRAM2 Stimuli-sensing channels FGFR1b ligand binding and activation HEPS GRM5 CCKARGHSR S1PR3 ProteinCyclin-dependent tyrosine phosphatase kinaseDUS22M3K12 2-associated receptorSENP6AminopeptidasePA2GC typeM3K10 proteinC-associated B2 protein FYV1 PKR1GRPREDNRACCKN OXER1S1PR4S1PR5 KLK6HDATAD5DYR1BXBP1 Enzymatic degradation of dopamine by COMT FGFR4FGFR2b ligand ligand binding binding and and activation activation PAR2 AssemblyAL1A1 of active LPL and LIPC lipaseTADBPFKBP3 CDKL5complexesDYRK3PASK Enzymatic degradation of DopamineDefective MTRby monoamine causes methylmalonic oxidase aciduriaL-type and amino homocystinuria acid transporter type cblG 1 PI4KB NTR2KISSRTRFRNTR1 LEG4GDF8PRUN1E2AK4ST17ACDK15LTKSHBGMMP26B3GT5 Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Activated point mutants of FGFR2ATS13 Muscarinic acetylcholine receptors ACM4 5HT2A5HT2B HINT1Q9BPW0BRSK1SLC16A10ENTK NEK1 protein EDNRBUR2R 5HT2C Class C/3 (Metabotropic glutamate/pheromone receptors) 43 kDa receptor-associatedXPP1ST32BGSHRKLF10 proteinGP174TNR5 of the synapse DCMC Gluconeogenesis NMUR1 CASR PPICM3K13KCJ13ST38LICKMAST4RECQ1 Abacavir metabolism NMUR2 MAST2GRB2SEPRPRKXTGM3MAST3 ADAL P4K2B BKRB1 SCRB1OXSR1EBPLAHSA1PIN4SRPK1CBG Guanylate kinase DefectiveRegulation TPR may conferof Glucokinase susceptibility by Glucokinase towards thyroid Regulatory papillary Protein carcinoma (TPC) BKRB2MCHR2 G-proteinRBBP9 coupledABC3FPTPRMSGMR1 receptorSTK33 12 Metal ion SLC transporters GCYB2 MCOLN3 protein O-glycosylation of TSR domain-containing proteins Phospholipase C-mediated cascade: FGFR1 GRM7 MRGX1BRSK2CELA1MYLK4DCLK3DPP9GBRDGP182CLK3SIR2 GCYA3GCYA2 TRPV1TRPA1TRPM8 Defective B3GALTL causes Peters-plus syndrome (PpS) Phospholipase C-mediated cascade; FGFR2 Signaling by MST1 CCRL2 GRM3 KC1AL GBRPQORDPOG1HMDH Catabolism ofHypusine glucuronate synthesis to xylulose-5-phosphate from eIF5A-lysine Iron uptake and transport GCYB1 TRPV4 CAC1D G alpha (q) signallingCX3C1 events GRM8 GHRLMPEG1CLK1DUS26PTN7MYLK2STK16M4K5UNG Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB TRPM6TRPV3 CAC1C ACM3 GRM4 Cyclin-dependentChymotrypsin-likeMucosal kinaseProteasomeNMD3A addressin 2-associated protease cellassemblyPRDX5 adhesionM3K6 protein CTRL-1 chaperone molecule-1 1 3 DeoxyhypusineDHSO synthase Potassium-transportingATP4A ATPaseTRPV6 alpha chain 2 P2RY2SSR1 GRM6GRM2 KCC1DMembrane-associatedKDM4ECDK14TNI3KCDK18TLK2COQ8A guanylatePI4KA/PI4KAP2MAKGPR52 HIPK3kinase-relatedFOLC 3 COMT ATP4B betaKlotho-mediatedSynthesis ligand of PIPs binding at the early endosome membrane FGF1 FGF4PTPM1 OXYRGALR2OPRX HKDC1KCC1GINSRRBis(5'-adenosyl)-triphosphataseGlyoxalaseNEK11CLK2 ELF3II PABP4GP142LEPRMAONCDKL2PEPDCCNB3CTDS1 AOFA Phospholipase C-mediated cascade; FGFR3 GPER1SSR5SSR4 MRCKANR2E3MELKBMP2KGP151PHF23ST17BCASP5 ST32CM3K2TYRO3SLK M4K3 FGFR4 mutant receptor activation MET Receptor Activation NK3RNK2R NPBW1APJ HRH1 BACE2SBK1CDKL3TDTM3K20GPR34TP4A1RNAS1M4K1MARK1STK35P4HTMMBTD1RIPK4SO3A1ACVR1ST32APPAC RIR1 LDLDCTD clearance Phospholipase C-mediated cascade; FGFR4 Peptide ligand-binding receptorsNPY5RAGTR2APEL 5HT1F5HT1B BAZ2BGRK4TOPKTM11DMultidrugNMD3BPGTB1SNRKTHBGSIR7 resistanceKC1G3BRD3SRPK3TLK1 associated protein Beta-oxidationPeroxisomal of very long carnitine chain O-octanoyltransferase fatty acids METH KTHY NPY1RSSR2 5HT1E5HT5A Human KLK4immunodeficiencyBRD4M4K2ThreonineNEK3CNCGERBB4SRR aspartaseLEG8 virusCDK3ROS1 1 typeDNAS1HUNK ACK1I NR5A2enhancer-bindingDYRK4 protein 1 KCY GLSK RYR1 Neurexins and neuroligins FFAR2FFAR3 NPY4RNPY2RGALR3GALR1CCR9CCR8 5HT1ASerotonin receptors ANM8AMPLMPP8PRP4BDGAT1MBNL1 DUTproteinNPCL1VRK2NISCHSMBT1CDK17WEE2AURKC KAD2 FKB1B CXCR5 5HT1D PIM3GRAKPPIDPTPREDEFME2AK1PTPRR PTN5PAR15PCSK7TNK1TP4A3 DHCR7 HPRT Basigin interactions PLCB FGF22 OPRK CXCR3CCR4ACKR3 Phospholipid transferTESK2OGAProteinPCSK4 LEG7proteinTSSK2CLK4 phosphataseHIPK4PEPCSBK3KCC1ADPP8S10A4 2ANR0B1 regulatory subunit B' AMPADA deaminase 2 TRPC5 PLPL9 FGF2 ThromboxanePAR4 signalling through TP receptor CCR3 KKCC2AspartylGPR88HASP aminopeptidasePPCELMBL4SRPK2ERBB3B2CL2EPORTMPS4NIM1 AOFB PPT1 ADK TWIK related potassium channel (TREK) PF2RPE2R1 FUT4MTAP2LRC59TGM2NF2L2CBX1NR1I2PDE6CSTK25ACHBPERFM3K4 S22A2 N-glycan trimming and elongation in the cis-Golgi Synthesis of PIPs at the late endosome membrane NF-kappa-B-repressingM3K19TSSK1MYO3BMethyl-CpG-bindingPLAPOGRL1 factorMK15DCLK1MRCKBTRXR3 protein 2 Beta-oxidation of pristanoyl-CoA S22A1SCD5 MGAT1 AT1B1AT1B2 V1BRV1AR P2Y12 LactoperoxidaseSTK38DUSTYTAOK2FUT6MARK2LMBL3MKNK2BIRC8ACH10KC1G1PARP3 Nitric oxide stimulates guanylate cyclase AT1B3FGFR2 Synthesis
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