SunLong Biotech Co.,LTD Tel: 0086-571- 56623320 Fax:0086-571- 56623318 E-mail:[email protected] www.sunlongbiotech.com

Rabbit Anti-KRT23 antibody

SL16818R

Product Name: KRT23 Chinese Name: 细胞角蛋白23抗体 CK 23; CK-23; CK23; 23; Cytokeratin-23; Cytokeratin23; DKFZP434G032; HAIK 1; HAIK1; Histone deacetylase inducible 23; Hyperacetylation inducible ; K1C23_HUMAN; K23; Keratin 23 (histone Alias: deacetylase inducible); Keratin 23; Keratin; Keratin type I cytoskeletal 23; Keratin-23; Keratin23; KRT 23; KRT23; MGC26158; type I cytoskeletal 23; Type I cytokeratin. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, WB=1:500-2000ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100- 500IF=1:100-500（Paraffin sections need antigen repair） Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 48kDa Cellular localization: cytoplasmic Form: Lyophilizedwww.sunlongbiotech.com or Liquid Concentration: 1mg/ml KLH conjugated synthetic peptide derived from human KRT23:26- immunogen: 120/462 Lsotype: IgG Purification: affinity purified by A Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed: PubMed Product Detail: The protein encoded by this is a member of the keratin family. The are intermediate filament responsible for the structural integrity of epithelial cells and are subdivided into and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin are clustered in a region of 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta- signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane (By similarity).

Subunit: Interacts with ERLEC1 (By similarity).

Subcellular Location: Membrane; Single-pass type I membrane protein (Potential).

Similarity: Contains 1 CUB domain. Contains 1 kringle domain. Contains 1 WSC domain.

SWISS: Q9C075

Gene ID: 25984

Database links:

Entrez Gene: 25984 Human Omim:www.sunlongbiotech.com 606194 Human SwissProt: Q9C075 Human

Unigene: 9029 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.