Max Planck As Editor of the Annalen Der Physik
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Warburg Effect(S)—A Biographical Sketch of Otto Warburg and His Impacts on Tumor Metabolism Angela M
Otto Cancer & Metabolism (2016) 4:5 DOI 10.1186/s40170-016-0145-9 REVIEW Open Access Warburg effect(s)—a biographical sketch of Otto Warburg and his impacts on tumor metabolism Angela M. Otto Abstract Virtually everyone working in cancer research is familiar with the “Warburg effect”, i.e., anaerobic glycolysis in the presence of oxygen in tumor cells. However, few people nowadays are aware of what lead Otto Warburg to the discovery of this observation and how his other scientific contributions are seminal to our present knowledge of metabolic and energetic processes in cells. Since science is a human endeavor, and a scientist is imbedded in a network of social and academic contacts, it is worth taking a glimpse into the biography of Otto Warburg to illustrate some of these influences and the historical landmarks in his life. His creative and innovative thinking and his experimental virtuosity set the framework for his scientific achievements, which were pioneering not only for cancer research. Here, I shall allude to the prestigious family background in imperial Germany; his relationships to Einstein, Meyerhof, Krebs, and other Nobel and notable scientists; his innovative technical developments and their applications in the advancement of biomedical sciences, including the manometer, tissue slicing, and cell cultivation. The latter were experimental prerequisites for the first metabolic measurements with tumor cells in the 1920s. In the 1930s–1940s, he improved spectrophotometry for chemical analysis and developed the optical tests for measuring activities of glycolytic enzymes. Warburg’s reputation brought him invitations to the USA and contacts with the Rockefeller Foundation; he received the Nobel Prize in 1931. -
The Optical Thin-Film Model: Part 2
qM qMqM Previous Page | Contents |Zoom in | Zoom out | Front Cover | Search Issue | Next Page qMqM Qmags THE WORLD’S NEWSSTAND® The Optical Thin-Film Model: Part 2 Angus Macleod Thin Film Center, Inc., Tucson, AZ Contributed Original Article n part 1 of this account [1] we covered the early attempts to topics but for our present account it is his assembly of electricity Iunderstand the phenomenon of light but heavily weighted and magnetism into a coherent connected theory culminating in towards the optics of thin ilms. Acceptance of the wave theory the prediction of a wave combining electric and magnetic ields and followed the great contributions of Young and Fresnel. We found traveling at the speed of light that most interests us. an almost completely modern account of the fundamentals of Maxwell’s ideas of electromagnetism were much inluenced by optics in Airy’s Mathematical Tracts but omitting any ideas of Michael Faraday (1791-1867). Faraday was born in the south of absorption loss. hus, by the 1830’s multiple beam interference in England to a family with few resources and was essentially self single ilms was well organized with expressions that could be used educated. His apprenticeship with a local bookbinder allowed for accurate calculation in dielectrics. Lacking in all this, however, him access to books and he read voraciously and developed an was an appreciation of the real nature of the light wave. At this interest in science, nourished by his attendance at lectures in the stage the models were mechanical with Fresnel’s ideas of an array Royal Institution of Great Britain. -
Transparent Conductive Oxides – Fundamentals and Applications Agenda
BuildMoNa Symposium 2019 Transparent Conductive Oxides – Fundamentals and Applications Monday, 23 September to Friday, 27 September 2019 Universität Leipzig, 04103 Leipzig, Linnéstr. 5, Lecture Hall for Theoretical Physics Agenda Monday, 23 September 2019 13:00 Prof. Dr. Marius Grundmann Universität Leipzig, Germany Opening 13:05 Dr. Debdeep Jena* Cornell University, USA Paul Drude Lecture I: The Drude Model Lives On: Its Simplicity and Hidden Powers 13:50 Prof. Vanya Darakchieva* Linköping University, Sweden Paul Drude Lecture II: Optical properties of the electron gas 14:35 Dr. Robert Karsthof University of Oslo, Norway Revisiting the electronic transport in doped nickel oxide *Invited talk 1 14:50 Dr. Petr Novák University of West Bohemia, Plzeň, Czech Republic Important factors influencing the electrical properties of sputtered AZO thin films 15:05 Coffee break (Aula) 15:35 Dr. Andriy Zakutayev* National Renewable Energy Laboratory, USA Wide Band Gap Chalcogenide Semiconductors 16:20 Alexander Koch Universität Jena, Germany Ion Beam Doped Transparent Conductive Oxides for Metasurfaces 16:35 Prof. Chris van de Walle* UC Santa Barbara, USA Fundamental limits on transparency of transparent conducting oxides *Invited talk 2 Tuesday, 24 September 2019 08:15 Excursion BMW Group Plant Leipzig Departure by bus from Leipzig, Linnéstr. 5 09:15 Start Excursion BMW Visitor Center 12:15 Departure by bus from BMW Visitor Center 12:45 Lunch (Aula) 14:30 Prof. Dr. Pedro Barquinha* Universidade Nova de Lisboa, Portugal Towards autonomous flexible electronic systems with zinc-tin oxide thin films and nanostructures 15:15 Dr. Saud Bin Anooz Leibniz Institute for Crystal Growth, Berlin, Germany Optimization of β-Ga2O3 film growth on miscut (100) β-Ga2O3 substrates by MOVPE 15:30 Dr. -
Einstein and Physics Hundred Years Ago∗
Vol. 37 (2006) ACTA PHYSICA POLONICA B No 1 EINSTEIN AND PHYSICS HUNDRED YEARS AGO∗ Andrzej K. Wróblewski Physics Department, Warsaw University Hoża 69, 00-681 Warszawa, Poland [email protected] (Received November 15, 2005) In 1905 Albert Einstein published four papers which revolutionized physics. Einstein’s ideas concerning energy quanta and electrodynamics of moving bodies were received with scepticism which only very slowly went away in spite of their solid experimental confirmation. PACS numbers: 01.65.+g 1. Physics around 1900 At the turn of the XX century most scientists regarded physics as an almost completed science which was able to explain all known physical phe- nomena. It appeared to be a magnificent structure supported by the three mighty pillars: Newton’s mechanics, Maxwell’s electrodynamics, and ther- modynamics. For the celebrated French chemist Marcellin Berthelot there were no major unsolved problems left in science and the world was without mystery. Le monde est aujourd’hui sans mystère— he confidently wrote in 1885 [1]. Albert A. Michelson was of the opinion that “The more important fundamen- tal laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote . Our future dis- coveries must be looked for in the sixth place of decimals” [2]. Physics was not only effective but also perfect and beautiful. Henri Poincaré maintained that “The theory of light based on the works of Fresnel and his successors is the most perfect of all the theories of physics” [3]. -
Otto Sackur's Pioneering Exploits in the Quantum Theory Of
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Catalogo dei prodotti della ricerca Chapter 3 Putting the Quantum to Work: Otto Sackur’s Pioneering Exploits in the Quantum Theory of Gases Massimiliano Badino and Bretislav Friedrich After its appearance in the context of radiation theory, the quantum hypothesis rapidly diffused into other fields. By 1910, the crisis of classical traditions of physics and chemistry—while taking the quantum into account—became increas- ingly evident. The First Solvay Conference in 1911 pushed quantum theory to the fore, and many leading physicists responded by embracing the quantum hypoth- esis as a way to solve outstanding problems in the theory of matter. Until about 1910, quantum physics had drawn much of its inspiration from two sources. The first was the complex formal machinery connected with Max Planck’s theory of radiation and, above all, its close relationship with probabilis- tic arguments and statistical mechanics. The fledgling 1900–1901 version of this theory hinged on the application of Ludwig Boltzmann’s 1877 combinatorial pro- cedure to determine the state of maximum probability for a set of oscillators. In his 1906 book on heat radiation, Planck made the connection with gas theory even tighter. To illustrate the use of the procedure Boltzmann originally developed for an ideal gas, Planck showed how to extend the analysis of the phase space, com- monplace among practitioners of statistical mechanics, to electromagnetic oscil- lators (Planck 1906, 140–148). In doing so, Planck identified a crucial difference between the phase space of the gas molecules and that of oscillators used in quan- tum theory. -
Hermann Minkowski Et La Mathématisation De La Théorie De La Relativité Restreinte 1905-1915
THÈSE présentée à L’UNIVERSITÉ DE PARIS VII pour obtenir le grade de DOCTEUR Spécialité : Épistémologie et Histoire des Sciences par Scott A. WALTER HERMANN MINKOWSKI ET LA MATHÉMATISATION DE LA THÉORIE DE LA RELATIVITÉ RESTREINTE 1905-1915 Thèse dirigée par M. Christian Houzel et soutenue le 20 décembre 1996 devant la Commission d’Examen composée de : Examinateur : M. Christian Houzel Professeur à l’Université de Paris VII Examinateur : M. Arthur I. Miller Professeur à UniversityCollege London Rapporteur : M. Michel Paty Directeur de recherche, CNRS Rapporteur : M. Jim Ritter Maître de conférences à l’Univ. de Paris VIII S. Walter LA MATHÉMATISATION DE LA RELATIVITÉ RESTREINTE i Résumé Au début du vingtième siècle émergeait l’un des produits les plus remarquables de la physique théorique : la théorie de la relativité. Prise dans son contexte à la fois intellectuel et institution- nel, elle est l’objet central de la dissertation. Toutefois, seul un aspect de cette histoire est abordé de façon continue, à savoir le rôle des mathématiciens dans sa découverte, sa diffusion, sa ré- ception et son développement. Les contributions d’un mathématicien en particulier, Hermann Minkowski, sont étudiées de près, car c’est lui qui trouva la forme mathématique permettant les développements les plus importants, du point de vue des théoriciens de l’époque. Le sujet de la thèse est abordé selon deux axes; l’un se fonde sur l’analyse comparative des documents, l’autre sur l’étude bibliométrique. De cette façon, les conclusions de la première démarche se trouvent encadrées par les résultats de l’analyse globale des données bibliographiques. -
Design of Experiments for Light Speed Invariance to Moving Observers
Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 24 February 2021 doi:10.20944/preprints202102.0547.v1 DESIGN OF EXPERIMENTS FOR LIGHT SPEED INVARIANCE TO MOVING OBSERVERS Design of experiments for light speed invariance to moving observers Revised 2/22/2021 08:08:00 Qian Chen International Education Foundation 4667 Highland Ct, Grandville, MI, USA 49418 e-mail: [email protected] The principle of the constancy of the velocity of light, which stated that the light velocity is invariant to the motion of the emitter, was well established and directly proven by experiments. Interestingly, the further assumption that the light velocity is independent of the motion of the observer was, arguably, never directly proven by any experiment for a century. This paper proposed the design of two experiments to directly test this assumption, which tried to address some perceived technical difficulty in such experiments. One is to directly measure the light speed as to moving sensors. The experiment setup is designed in such a way that the concerns of time synchronization and dilation can be avoided. Another experiment is to test the isotropy of the light speed to a moving particle in the electromagnetic accelerator by measuring the momentum to acceleration ratio. The experiment result, if positive, will provide direct and solid proof of the assumption. Otherwise, it may imply a need for further investigation. Since the light speed invariance to moving observers is a key assumption of some fundamental physical theory, either way, the experiments will have significant meanings. Keywords: Light velocity, Special Relativity, Time dilation, Time synchronization, Sagnac effect, Mass- Energy relationship, Particle acceleration, Michelson-Morley experiment, Asymmetry Theory search for direct experimental proof is of significant I. -
The Collaboration of Mileva Marić and Albert Einstein
Asian Journal of Physics Vol 24, No 4 (2015) March The collaboration of Mileva Marić and Albert Einstein Estelle Asmodelle University of Central Lancashire School of Computing, Engineering and Physical Sciences, Preston, Lancashire, UK PR1 2HE. e-mail: [email protected]; Phone: +61 418 676 586. _____________________________________________________________________________________ This is a contemporary review of the involvement of Mileva Marić, Albert Einstein’s first wife, in his theoretical work between the period of 1900 to 1905. Separate biographies are outlined for both Mileva and Einstein, prior to their attendance at the Swiss Federal Polytechnic in Zürich in 1896. Then, a combined journal is described, detailing significant events. In additional to a biographical sketch, comments by various authors are compared and contrasted concerning two narratives: firstly, the sequence of events that happened and the couple’s relationship at particular times. Secondly, the contents of letters from both Einstein and Mileva. Some interpretations of the usage of pronouns in those letters during 1899 and 1905 are re-examined, and a different hypothesis regarding the usage of those pronouns is introduced. Various papers are examined and the content of each subsequent paper is compared to the work that Mileva was performing. With a different take, this treatment further suggests that the couple continued to work together much longer than other authors have indicated. We also evaluate critics and supporters of the hypothesis that Mileva was involved in Einstein’s work, and refocus this within a historical context, in terms of women in science in the late 19th century. Finally, the definition of, collaboration (co-authorship, specifically) is outlined. -
Chronological List of Correspondence, 1895–1920
CHRONOLOGICAL LIST OF CORRESPONDENCE, 1895–1920 In this chronological list of correspondence, the volume and document numbers follow each name. Documents abstracted in the calendars are listed in the Alphabetical List of Texts in this volume. 1895 13 or 20 Mar To Mileva Maric;;, 1, 45 29 Apr To Rosa Winteler, 1, 46 Summer To Caesar Koch, 1, 6 18 May To Rosa Winteler, 1, 47 28 Jul To Julia Niggli, 1, 48 Aug To Rosa Winteler, 5: Vol. 1, 48a 1896 early Aug To Mileva Maric;;, 1, 50 6? Aug To Julia Niggli, 1, 51 21 Apr To Marie Winteler, with a 10? Aug To Mileva Maric;;, 1, 52 postscript by Pauline Einstein, after 10 Aug–before 10 Sep 1,18 From Mileva Maric;;, 1, 53 7 Sep To the Department of Education, 10 Sep To Mileva Maric;;, 1, 54 Canton of Aargau, 1, 20 11 Sep To Julia Niggli, 1, 55 4–25 Nov From Marie Winteler, 1, 29 11 Sep To Pauline Winteler, 1, 56 30 Nov From Marie Winteler, 1, 30 28? Sep To Mileva Maric;;, 1, 57 10 Oct To Mileva Maric;;, 1, 58 1897 19 Oct To the Swiss Federal Council, 1, 60 May? To Pauline Winteler, 1, 34 1900 21 May To Pauline Winteler, 5: Vol. 1, 34a 7 Jun To Pauline Winteler, 1, 35 ? From Mileva Maric;;, 1, 61 after 20 Oct From Mileva Maric;;, 1, 36 28 Feb To the Swiss Department of Foreign Affairs, 1, 62 1898 26 Jun To the Zurich City Council, 1, 65 29? Jul To Mileva Maric;;, 1, 68 ? To Maja Einstein, 1, 38 1 Aug To Mileva Maric;;, 1, 69 2 Jan To Mileva Maric;; [envelope only], 1 6 Aug To Mileva Maric;;, 1, 70 13 Jan To Maja Einstein, 8: Vol. -
530 Book Reviews
530 Book reviews found in the progressive stages of certainty brought about by systematic actions over nature rather than passive contemplation; authorization was the basic role of the House of Solomon, later to be materialized in the Royal Society; confirmation is related to all the personal virtues of the natural phil- osopher as prophet and gentleman (patience, self-sacrifice, constancy etc.); divination is identified with the inductive method; and prophecy appears in the supposedly plain style of reporting which included genres such as fables and aphorisms for the outsider in order to generate more debate. In Chapter 4 the book delves into the analogy between the prophetic temples as loci outside the polis and the Royal Society as a supposedly neutral environment in the political unrest of seventeenth-century England. After an interlude in which the author establishes an important distinction between the expert (who offers knowledge as if attainable by the majority) and the prophet (who presents knowledge as beyond the reach of the general public), the second part of the book takes us to America in the second half of the twentieth century. J. Robert Oppenheimer’s self-portrayal before, during and after his trial and Rachel Carson’s use of mass media are the two main examples Walsh presents of modern individual prophets: the former as a cultic prophet, an apostle for peace and a victim of political fear; the latter as an average housewife on the peripheries of academic science and political decisions creating a kairos for public debate on pesticides. More difficult to follow is the argument of Chapter 9 on the rhetorical technologies of climate change, where advocates and deniers of the importance of climate change seem to replicate prophetic patterns such as the accusation of bias in the opponents’ reports or the mixture of present description and future predictions. -
Voigt Transformations in Retrospect: Missed Opportunities?
Voigt transformations in retrospect: missed opportunities? Olga Chashchina Ecole´ Polytechnique, Palaiseau, France∗ Natalya Dudisheva Novosibirsk State University, 630 090, Novosibirsk, Russia† Zurab K. Silagadze Novosibirsk State University and Budker Institute of Nuclear Physics, 630 090, Novosibirsk, Russia.‡ The teaching of modern physics often uses the history of physics as a didactic tool. However, as in this process the history of physics is not something studied but used, there is a danger that the history itself will be distorted in, as Butterfield calls it, a “Whiggish” way, when the present becomes the measure of the past. It is not surprising that reading today a paper written more than a hundred years ago, we can extract much more of it than was actually thought or dreamed by the author himself. We demonstrate this Whiggish approach on the example of Woldemar Voigt’s 1887 paper. From the modern perspective, it may appear that this paper opens a way to both the special relativity and to its anisotropic Finslerian generalization which came into the focus only recently, in relation with the Cohen and Glashow’s very special relativity proposal. With a little imagination, one can connect Voigt’s paper to the notorious Einstein-Poincar´epri- ority dispute, which we believe is a Whiggish late time artifact. We use the related historical circumstances to give a broader view on special relativity, than it is usually anticipated. PACS numbers: 03.30.+p; 1.65.+g Keywords: Special relativity, Very special relativity, Voigt transformations, Einstein-Poincar´epriority dispute I. INTRODUCTION Sometimes Woldemar Voigt, a German physicist, is considered as “Relativity’s forgotten figure” [1]. -
Theory and Experiment in the Quantum-Relativity Revolution
Theory and Experiment in the Quantum-Relativity Revolution expanded version of lecture presented at American Physical Society meeting, 2/14/10 (Abraham Pais History of Physics Prize for 2009) by Stephen G. Brush* Abstract Does new scientific knowledge come from theory (whose predictions are confirmed by experiment) or from experiment (whose results are explained by theory)? Either can happen, depending on whether theory is ahead of experiment or experiment is ahead of theory at a particular time. In the first case, new theoretical hypotheses are made and their predictions are tested by experiments. But even when the predictions are successful, we can’t be sure that some other hypothesis might not have produced the same prediction. In the second case, as in a detective story, there are already enough facts, but several theories have failed to explain them. When a new hypothesis plausibly explains all of the facts, it may be quickly accepted before any further experiments are done. In the quantum-relativity revolution there are examples of both situations. Because of the two-stage development of both relativity (“special,” then “general”) and quantum theory (“old,” then “quantum mechanics”) in the period 1905-1930, we can make a double comparison of acceptance by prediction and by explanation. A curious anti- symmetry is revealed and discussed. _____________ *Distinguished University Professor (Emeritus) of the History of Science, University of Maryland. Home address: 108 Meadowlark Terrace, Glen Mills, PA 19342. Comments welcome. 1 “Science walks forward on two feet, namely theory and experiment. ... Sometimes it is only one foot which is put forward first, sometimes the other, but continuous progress is only made by the use of both – by theorizing and then testing, or by finding new relations in the process of experimenting and then bringing the theoretical foot up and pushing it on beyond, and so on in unending alterations.” Robert A.