DMD Fast Forward. Published on September 12, 2014 as DOI: 10.1124/dmd.114.059675 This article has not been copyedited and formatted. The final version may differ from this version. DMD #59675 Disposition and Metabolic Profiling of [14C]Cerlapirdine Utilizing Accelerator Mass Spectrometry (AMS) Susanna Tse, Louis Leung, Sangeeta Raje, Mark Seymour, Yoko Shishikura, R. Scott Obach Pfizer Inc., Groton, CT (S.T., L.L., R.S.O.) and Collegeville PA (S.R.); Xceleron Inc., Germantown, MD (M.S., Y.S.) Downloaded from dmd.aspetjournals.org at ASPET Journals on September 26, 2021 1 DMD Fast Forward. Published on September 12, 2014 as DOI: 10.1124/dmd.114.059675 This article has not been copyedited and formatted. The final version may differ from this version. DMD #59675 Running Title: Metabolism of Cerlapirdine in Humans Address Correspondence to: Susanna Tse Pharmacokinetics, Dynamics and Metabolism-New Chemical Entities Pfizer Inc. Eastern Point Road Downloaded from Groton, CT 06340, USA. Telephone number: 1-860-715-5942 dmd.aspetjournals.org Fax number: 1-860-715-6427 Email:
[email protected] at ASPET Journals on September 26, 2021 Text Pages (including references): 36 Tables: 3 Figures: 9 References: 44 Words in: Abstract: 242 Introduction: 617 Discussion: 1198 2 DMD Fast Forward. Published on September 12, 2014 as DOI: 10.1124/dmd.114.059675 This article has not been copyedited and formatted. The final version may differ from this version. DMD #59675 Abbreviations used: PF-05212365: N,N-dimethyl-3-{[3-(naphthalen-1-ylsulfonyl)-2H- indazol-5-yl]oxy}propan-1-amine;