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Chemistry and Pharmacology of Kinkéliba (Combretum
CHEMISTRY AND PHARMACOLOGY OF KINKÉLIBA (COMBRETUM MICRANTHUM), A WEST AFRICAN MEDICINAL PLANT By CARA RENAE WELCH A Dissertation submitted to the Graduate School-New Brunswick Rutgers, The State University of New Jersey in partial fulfillment of the requirements for the degree of Doctor of Philosophy Graduate Program in Medicinal Chemistry written under the direction of Dr. James E. Simon and approved by ______________________________ ______________________________ ______________________________ ______________________________ New Brunswick, New Jersey January, 2010 ABSTRACT OF THE DISSERTATION Chemistry and Pharmacology of Kinkéliba (Combretum micranthum), a West African Medicinal Plant by CARA RENAE WELCH Dissertation Director: James E. Simon Kinkéliba (Combretum micranthum, Fam. Combretaceae) is an undomesticated shrub species of western Africa and is one of the most popular traditional bush teas of Senegal. The herbal beverage is traditionally used for weight loss, digestion, as a diuretic and mild antibiotic, and to relieve pain. The fresh leaves are used to treat malarial fever. Leaf extracts, the most biologically active plant tissue relative to stem, bark and roots, were screened for antioxidant capacity, measuring the removal of a radical by UV/VIS spectrophotometry, anti-inflammatory activity, measuring inducible nitric oxide synthase (iNOS) in RAW 264.7 macrophage cells, and glucose-lowering activity, measuring phosphoenolpyruvate carboxykinase (PEPCK) mRNA expression in an H4IIE rat hepatoma cell line. Radical oxygen scavenging activity, or antioxidant capacity, was utilized for initially directing the fractionation; highlighted subfractions and isolated compounds were subsequently tested for anti-inflammatory and glucose-lowering activities. The ethyl acetate and n-butanol fractions of the crude leaf extract were fractionated leading to the isolation and identification of a number of polyphenolic ii compounds. -
Phytochemical Screening and Antimicrobial Studies of Afzelia Africana and Detarium Microcarpum Seeds
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by ZENODO ISSN: 2410-9649 FridayChemistry et al / InternationalChemistry International 4(3) (2018 4(3)) 170 (2018)-176 1 70-176 iscientic.org. Phytochemical screening and antimicrobial studies of afzelia africana and detarium microcarpum seeds Chisom Friday*, Ugochukwu Akwada and Okenwa U. Igwe Department of Chemistry, Michael Okpara University of Agriculture, Umudike, P.M.B. 7267 Umuahia, Abia State, Nigeria *Corresponding author’s E. mail: [email protected] ARTICLE INFO ABSTRACT Article type: The aim of this study was to probe the phytochemical constituents and the Research article antimicrobial activities of Afzelia africana and Detarium microcarpum seed Article history: endosperms. The results obtained from the phytochemical screening indicated Received March 2017 that tannins, flavonoids, fatty acids, phenol, steroids, saponins and alkaloids were Accepted May 2017 present. The seed extracts were tested against eight pathogenic organisms July 2018 Issue comprising of two Gram positive and two Gram negative bacteria; two fungi and Keywords: two viruses using Agar and Disc diffusion methods. The plant extracts exhibited Afzelia Africana antimicrobial activities against all the tested organisms. This investigation Detarium microcarpum therefore, suggests the incorporation of Afzelia africana and Detarium Antimicrobial activities microcarpum seeds into human diets as they are rich in medicinal agents that Phytochemical screening could trigger great physiological effects. It also authenticates their use as soup Pathogenic organisms thickeners in eastern Nigeria and in the production of snacks. © 2018 International Scientific Organization: All rights reserved. Capsule Summary: The phytochemical constituents of Afzelia Africana and Detarium microcarpum seed endosperms were investigated and tannins, flavonoids, fatty acids, phenols, steroids, saponins and alkaloids were present. -
Actes Du 15E Colloque Sur Les Orchidées De La Société Française D’Orchidophilie
Cah. Soc. Fr. Orch., n° 7 (2010) – Actes 15e colloque de la Société Française d’Orchidophilie, Montpellier Actes du 15e colloque sur les Orchidées de la Société Française d’Orchidophilie du 30 mai au 1er juin 2009 Montpellier, Le Corum Comité d’organisation : Daniel Prat, Francis Dabonneville, Philippe Feldmann, Michel Nicole, Aline Raynal-Roques, Marc-Andre Selosse, Bertrand Schatz Coordinateurs des Actes Daniel Prat & Bertrand Schatz Affiche du Colloque : Conception : Francis Dabonneville Photographies de Francis Dabonneville & Bertrand Schatz Cahiers de la Société Française d’Orchidophilie, N° 7, Actes du 15e Colloque sur les orchidées de la Société Française d’Orchidophilie. ISSN 0750-0386 © SFO, Paris, 2010 Certificat d’inscription à la commission paritaire N° 55828 ISBN 978-2-905734-17-4 Actes du 15e colloque sur les Orchidées de la Société Française d’Orchidophilie, D. Prat et B. Schatz, Coordinateurs, SFO, Paris, 2010, 236 p. Société Française d’Orchidophilie 17 Quai de la Seine, 75019 Paris Cah. Soc. Fr. Orch., n° 7 (2010) – Actes 15e colloque de la Société Française d’Orchidophilie, Montpellier Préface Ce 15e colloque marque le 40e anniversaire de notre société, celle-ci ayant vu le jour en 1969. Notre dernier colloque se tenait il y a 10 ans à Paris en 1999, 10 ans c’est long, 10 ans c’est très loin. Il fallait que la SFO renoue avec cette traditionnelle organisation de colloques, manifestation qui a contribué à lui accorder la place prépondérante qu’elle occupe au sein des orchidophiles français et de la communauté scientifique. C’est chose faite aujourd’hui. Nombreux sont les thèmes qui font l’objet de communications par des intervenants dont les compétences dans le domaine de l’orchidologie ne sont plus à prouver. -
INVENTAIRE DES ORCHIDEES DE TALATAKELY PARC NATIONAL DE RANOMAFANA ETUDES MORPHOLOGIQUE ET MOLECULAIRE DE CINQ ESPECES DU GENRE Aerangis (Rchb.F.)
UNIVERSITE D’ANTANANARIVO FACULTE DES SCIENCES Département de Biologie et Ecologie Végétales Mémoire pour l’obtention du Diplôme d’Etudes Approfondies (D.E.A.) En Biologie et Ecologie Végétales OPTION : ECOLOGIE VEGETALE INVENTAIRE DES ORCHIDEES DE TALATAKELY PARC NATIONAL DE RANOMAFANA ETUDES MORPHOLOGIQUE ET MOLECULAIRE DE CINQ ESPECES DU GENRE Aerangis (Rchb.f.) Présenté par RANDRIANINDRINA Veloarivony Rence Aimée (Maître ès Sciences) Soutenu publiquement le, 31 Janvier 2008 Devant la Commission de jury composée de : Président : Pr. RAJERIARISON Charlotte Examinateurs : Dr. RABAKONANDRIANINA Elisabeth Dr. FALINIAINA Lucien Rapporteurs : Dr. RAKOUTH Bakolimalala Dr. EDWARD Louis Jr. 1 UNIVERSITE D’ANTANANARIVO FACULTE DES SCIENCES Département de Biologie et Ecologie Végétales Mémoire pour l’obtention du Diplôme d’Etudes Approfondies (D.E.A.) En Biologie et Ecologie Végétales OPTION : ECOLOGIE VEGETALE INVENTAIRE DES ORCHIDEES DE TALATAKELY PARC NATIONAL DE RANOMAFANA ETUDES MORPHOLOGIQUE ET MOLECULAIRE DE CINQ ESPECES DU GENRE Aerangis (Rchb.f.) Présenté par RANDRIANINDRINA Veloarivony Rence Aimée (Maître ès Sciences) Soutenu publiquement le, 31 Janvier 2008 Devant la Commission de jury composée de : Président : Pr. Charlotte RAJERIARISON Examinateurs : Dr. Elisabeth RABAKONANDRIANINA Dr Lucien. FALINIAINA Rapporteurs : Dr. Bakolimalala RAKOUTH Dr. Louis Jr. EDWARD 2 REMERCIEMENTS En premier lieu, nous voudrions rendre gloire à Dieu pour sa bienveillance et sa bénédiction. Mené à terme ce mémoire, est le fruit de la collaboration entre -
Antidiabetic Activity of the Root Extract of Detarium Microcarpum (Fabacaee) Guill and Perr
Phytopharmacology 2012, 3(1) 12-18 Antidiabetic activity of the root extract of Detarium microcarpum (Fabacaee) Guill and Perr. 1 2,* 3 Christian Ejike Okolo , Peter Achunike Akah , Samuel Uchnna Uzodinma 1 Department of Pharmacognosy and Environmental Medicine. University of Nigeria Nsukka, Nigeria. 2 Department of Pharmacology and Toxicology. University of Nigeria Nsukka, Nigeria. 3 Department of Clinical Pharmacy, Nnamdi Azikwe University of Awka,. Nigeria. *Corresponding Author: [email protected] Received: 10 March 2012, Revised: 26 March 2012, Accepted: 26 March 2012 Abstract Diabetes mellitus is a common endocrine disorder that impairs glucose homeostasis resulting in severe diabetic complications including retinopathy, angiopathy, nephr- opathy, and neuropathy thus causing neurological disorder. In this study, antidiabe- tic activity of root extract of Detarium microcapum was investigated in rat model of diabetes. A methanol root extract was prepared by soxhlet extraction and was separated into fraction using chloroform, n-hexane and methanol to yield chlorof- orm fraction (CF), n-hexane fraction (HF) and methanol fraction (MF). The extract and its fractions were screened for phytochemicals using standard methods. The acute toxicity (LD ) of the extract was determined in mice. Diabetes was induced 50 by a single ip injection of 120 mg/kg of alloxan monohydrate and glucose level was analyzed as indices of diabetes. The acute toxicity test showed that the root bark extract was safe at doses of up to 5 g/kg. The phytochemical screening of the plant revealed the presence of proteins, carbohydrates and terpenoids in large amount while saponins, resins, glycosides and flavonoids were present in moderate amount. The results indicated that intraperitoneal injection of ME, MF, CF and HF reversed the effect of alloxan in rats by different degrees. -
Review on Combretaceae Family
Int. J. Pharm. Sci. Rev. Res., 58(2), September - October 2019; Article No. 04, Pages: 22-29 ISSN 0976 – 044X Review Article Review on Combretaceae Family Soniya Rahate*, Atul Hemke, Milind Umekar Department of Quality Assurance, Shrimati Kishoritai Bhoyar College of Pharmacy, Kamptee, Dist-Nagpur 441002, India. *Corresponding author’s E-mail: [email protected] Received: 06-08-2019; Revised: 22-09-2019; Accepted: 28-09-2019. ABSTRACT Combretaceae, the family of flowering plants consisting of 20 genus and 600 important species in respective genus. The two largest genera of the family are Combretum and Terminalia which contains the more no. of species. The members of the family are widely distributed in tropical and subtropical regions of the world. Most members of the trees, shrubs or lianas of the combretaceae family are widely used medicinally. The members of this family contain the different phytoconstituents of medicinal value e.g tannins, flavonoids, terpenoids and alkaloids. Most of the species of this family are used as antimicrobial, antioxidant and antifungal. The biological activities of the some members of this family yet not found. Apart from the medicinal value many members of the Combretaceae are of culinary and ornamental value. Keywords: Combretaceae, Tannins, Flavonoid, Terminalia, Combretum. INTRODUCTION species of Combretum have edible kernels whereas Buchenavia species have edible succulent endocarps. he family combretaceae is a major group of Chemical constituents like tannins are also found in fruits, flowering plants (Angiosperms) included in the bark, leaves, roots and timber in buchenavia and order of Myrtales. Robert Brown established it in T terminalia genera. Many of the species are reputed to 1810 and its inclusion to the order is not in dispute. -
Flora Mediterranea 26
FLORA MEDITERRANEA 26 Published under the auspices of OPTIMA by the Herbarium Mediterraneum Panormitanum Palermo – 2016 FLORA MEDITERRANEA Edited on behalf of the International Foundation pro Herbario Mediterraneo by Francesco M. Raimondo, Werner Greuter & Gianniantonio Domina Editorial board G. Domina (Palermo), F. Garbari (Pisa), W. Greuter (Berlin), S. L. Jury (Reading), G. Kamari (Patras), P. Mazzola (Palermo), S. Pignatti (Roma), F. M. Raimondo (Palermo), C. Salmeri (Palermo), B. Valdés (Sevilla), G. Venturella (Palermo). Advisory Committee P. V. Arrigoni (Firenze) P. Küpfer (Neuchatel) H. M. Burdet (Genève) J. Mathez (Montpellier) A. Carapezza (Palermo) G. Moggi (Firenze) C. D. K. Cook (Zurich) E. Nardi (Firenze) R. Courtecuisse (Lille) P. L. Nimis (Trieste) V. Demoulin (Liège) D. Phitos (Patras) F. Ehrendorfer (Wien) L. Poldini (Trieste) M. Erben (Munchen) R. M. Ros Espín (Murcia) G. Giaccone (Catania) A. Strid (Copenhagen) V. H. Heywood (Reading) B. Zimmer (Berlin) Editorial Office Editorial assistance: A. M. Mannino Editorial secretariat: V. Spadaro & P. Campisi Layout & Tecnical editing: E. Di Gristina & F. La Sorte Design: V. Magro & L. C. Raimondo Redazione di "Flora Mediterranea" Herbarium Mediterraneum Panormitanum, Università di Palermo Via Lincoln, 2 I-90133 Palermo, Italy [email protected] Printed by Luxograph s.r.l., Piazza Bartolomeo da Messina, 2/E - Palermo Registration at Tribunale di Palermo, no. 27 of 12 July 1991 ISSN: 1120-4052 printed, 2240-4538 online DOI: 10.7320/FlMedit26.001 Copyright © by International Foundation pro Herbario Mediterraneo, Palermo Contents V. Hugonnot & L. Chavoutier: A modern record of one of the rarest European mosses, Ptychomitrium incurvum (Ptychomitriaceae), in Eastern Pyrenees, France . 5 P. Chène, M. -
Taxonomic Significance of Stamens and Pollen Morphology of Some
eISSN: 2357-044X Taeckholmia 40 (2020): 1-11 Taxonomic significance of stamens and pollen morphology of some selected taxa of Primulaceae in Egypt Mona Adel Shiha Biology and Geology Department, Faculty of Education, Alexandria University Corresponding author: [email protected] Abstract The circumscription study of Primulaceae is still uncertain and remains controversial. Stamens and pollen grains morphological characters of five species and one variety representing five genera viz., Anagallis, Lysimachia, Coris, Primula and Samolus of Primulaceae in Egypt have been studied using LM and SEM. The specific target of the present study is to evaluate the taxonomic value of the macro and micromorphological characters of stamens and pollen grains in order to distinguish between the studied species. The obtained results showed remarkable variations in anther shape, anther dehiscence, filament attachment and presence of trichomes on the anther filament. Pollen grains are radially symmetrical, isopolar, spheroidal-subprolate to prolate, with amb angulaperturate or fossaperturate and tricolpate or tricolporate. Tectum is microreticulate, reticulate with perforated lumine and clavate exine ornamentation. Out of the studied taxa Coris monspeliensis is distinguished by the presence of prominent margo, reticulate exine ornamentation, minute luminal perforations decreasing towards the colpi, orbicular anther shape, latrorse dehiscence of anthers with short longitudinal slit and presence of glandular diseriate trichomes at the base of the filaments. Clavate exine ornamentation as well as lanceolate anther shape, extrorse dehiscence and short filament can distinguished Samolus valerandi from the remaining studied taxa. An artificial key for the studied species was constructed based on stamens and pollen morphological criteria is provided. Keywords: Anther dehiscence, Exine ornamentation, Primulaceae, Pollen grain, Stamen Introduction Primulaceae (order Ericales) controversial. -
The Naturalized Vascular Plants of Western Australia 1
12 Plant Protection Quarterly Vol.19(1) 2004 Distribution in IBRA Regions Western Australia is divided into 26 The naturalized vascular plants of Western Australia natural regions (Figure 1) that are used for 1: Checklist, environmental weeds and distribution in bioregional planning. Weeds are unevenly distributed in these regions, generally IBRA regions those with the greatest amount of land disturbance and population have the high- Greg Keighery and Vanda Longman, Department of Conservation and Land est number of weeds (Table 4). For exam- Management, WA Wildlife Research Centre, PO Box 51, Wanneroo, Western ple in the tropical Kimberley, VB, which Australia 6946, Australia. contains the Ord irrigation area, the major cropping area, has the greatest number of weeds. However, the ‘weediest regions’ are the Swan Coastal Plain (801) and the Abstract naturalized, but are no longer considered adjacent Jarrah Forest (705) which contain There are 1233 naturalized vascular plant naturalized and those taxa recorded as the capital Perth, several other large towns taxa recorded for Western Australia, com- garden escapes. and most of the intensive horticulture of posed of 12 Ferns, 15 Gymnosperms, 345 A second paper will rank the impor- the State. Monocotyledons and 861 Dicotyledons. tance of environmental weeds in each Most of the desert has low numbers of Of these, 677 taxa (55%) are environmen- IBRA region. weeds, ranging from five recorded for the tal weeds, recorded from natural bush- Gibson Desert to 135 for the Carnarvon land areas. Another 94 taxa are listed as Results (containing the horticultural centre of semi-naturalized garden escapes. Most Total naturalized flora Carnarvon). -
Catalog2008 Missouri Botanical Garden Press
Missouri Botanical Garden Press catalog2008 Missouri Botanical Garden Press The mission of the Missouri Botanical Garden is to discover and share knowledge about plants and their environment, in order to preserve and enrich life. The Missouri Botanical Garden represents the botanical scholarship of the Research Division at the Missouri Botanical Garden in Saint Louis. Editorial responsibilities extend to the two peer-reviewed, quarterly journals Novon, A Journal for Botanical Nomenclature, and the Annals of the Missouri Botanical Garden. MBG Press produces and distributes other book-length titles and monographs, primarily in plant systematics and evolution. Fine art reproduction prints are also offered from the Library’s Rare Book collection. front cover image: Composite of Broad Prickly-toothed Buckler Fern and Hard Shield Fern, reprinted from the book The Ferns of Great Britain and Ireland, by Thomas Moore, 1855. Available from our Rare Book Print collection. See page 62 for order information. 2 Table of Contents New Titles......................................................................4–11 Full Title List....................................................................12-39 CD-ROMS............................................................17 Annals and Novon.......................................................40 Guide to Systematics Symposia........................41 Guide to the Flora of Panama Issues...............42-43 Monographs in Systematic Botany............................44-47 Orchids..........................................................................48-53 -
Rangelands, Western Australia
Biodiversity Summary for NRM Regions Species List What is the summary for and where does it come from? This list has been produced by the Department of Sustainability, Environment, Water, Population and Communities (SEWPC) for the Natural Resource Management Spatial Information System. The list was produced using the AustralianAustralian Natural Natural Heritage Heritage Assessment Assessment Tool Tool (ANHAT), which analyses data from a range of plant and animal surveys and collections from across Australia to automatically generate a report for each NRM region. Data sources (Appendix 2) include national and state herbaria, museums, state governments, CSIRO, Birds Australia and a range of surveys conducted by or for DEWHA. For each family of plant and animal covered by ANHAT (Appendix 1), this document gives the number of species in the country and how many of them are found in the region. It also identifies species listed as Vulnerable, Critically Endangered, Endangered or Conservation Dependent under the EPBC Act. A biodiversity summary for this region is also available. For more information please see: www.environment.gov.au/heritage/anhat/index.html Limitations • ANHAT currently contains information on the distribution of over 30,000 Australian taxa. This includes all mammals, birds, reptiles, frogs and fish, 137 families of vascular plants (over 15,000 species) and a range of invertebrate groups. Groups notnot yet yet covered covered in inANHAT ANHAT are notnot included included in in the the list. list. • The data used come from authoritative sources, but they are not perfect. All species names have been confirmed as valid species names, but it is not possible to confirm all species locations. -
Biodiversity Summary: Rangelands, Western Australia
Biodiversity Summary for NRM Regions Guide to Users Background What is the summary for and where does it come from? This summary has been produced by the Department of Sustainability, Environment, Water, Population and Communities (SEWPC) for the Natural Resource Management Spatial Information System. It highlights important elements of the biodiversity of the region in two ways: • Listing species which may be significant for management because they are found only in the region, mainly in the region, or they have a conservation status such as endangered or vulnerable. • Comparing the region to other parts of Australia in terms of the composition and distribution of its species, to suggest components of its biodiversity which may be nationally significant. The summary was produced using the Australian Natural Natural Heritage Heritage Assessment Assessment Tool Tool (ANHAT), which analyses data from a range of plant and animal surveys and collections from across Australia to automatically generate a report for each NRM region. Data sources (Appendix 2) include national and state herbaria, museums, state governments, CSIRO, Birds Australia and a range of surveys conducted by or for DEWHA. Limitations • ANHAT currently contains information on the distribution of over 30,000 Australian taxa. This includes all mammals, birds, reptiles, frogs and fish, 137 families of vascular plants (over 15,000 species) and a range of invertebrate groups. The list of families covered in ANHAT is shown in Appendix 1. Groups notnot yet yet covered covered in inANHAT ANHAT are are not not included included in the in the summary. • The data used for this summary come from authoritative sources, but they are not perfect.