OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for TA306750 alpha (TUBA1A) Chicken Polyclonal Antibody Product data:

Product Type: Primary Antibodies Applications: WB Recommended Dilution: WB: 0.5 - 1 ug/mL Reactivity: Human, Mouse, Rat Host: Chicken Isotype: IgY Clonality: Polyclonal Immunogen: Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin. Formulation: PBS containing 0.02% sodium azide. Concentration: 1ug/ul Purification: Affinity chromatography purified via peptide column Conjugation: Unconjugated Storage: Store at -20°C as received. Stability: Stable for 12 months from date of receipt. Name: tubulin alpha 1a Database Link: NP_006000 Gene 22142 MouseEntrez Gene 64158 RatEntrez Gene 7846 Human Q71U36

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 alpha Tubulin (TUBA1A) Chicken Polyclonal Antibody – TA306750

Background: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-, alpha-tubulins are the major components of . These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta- tubulin dimers are assembled to 13 protofilaments that form a of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a -associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-, this antibody makes an excellent loading control in immunoblots.

Synonyms: B-ALPHA-1; LIS3; TUBA3 Families: Druggable Genome Protein Pathways: Gap junction, Pathogenic Escherichia coli infection

Product images:

Western blot analysis of Tubulin in rat brain tissue lysate with Tubulin antibody at (A) 0.5 and (B) 1 ug/ml.

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2