Hangnails and Homoeopathy
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Nail Anatomy and Physiology for the Clinician 1
Nail Anatomy and Physiology for the Clinician 1 The nails have several important uses, which are as they are produced and remain stored during easily appreciable when the nails are absent or growth. they lose their function. The most evident use of It is therefore important to know how the fi ngernails is to be an ornament of the hand, but healthy nail appears and how it is formed, in we must not underestimate other important func- order to detect signs of pathology and understand tions, such as the protective value of the nail plate their pathogenesis. against trauma to the underlying distal phalanx, its counterpressure effect to the pulp important for walking and for tactile sensation, the scratch- 1.1 Nail Anatomy ing function, and the importance of fi ngernails and Physiology for manipulation of small objects. The nails can also provide information about What we call “nail” is the nail plate, the fi nal part the person’s work, habits, and health status, as of the activity of 4 epithelia that proliferate and several well-known nail features are a clue to sys- differentiate in a specifi c manner, in order to form temic diseases. Abnormal nails due to biting or and protect a healthy nail plate [1 ]. The “nail onychotillomania give clues to the person’s emo- unit” (Fig. 1.1 ) is composed by: tional/psychiatric status. Nail samples are uti- • Nail matrix: responsible for nail plate production lized for forensic and toxicology analysis, as • Nail folds: responsible for protection of the several substances are deposited in the nail plate nail matrix Proximal nail fold Nail plate Fig. -
Sweat Glands • Oil Glands • Mammary Glands
Chapter 4 The Integumentary System Lecture Presentation by Steven Bassett Southeast Community College © 2015 Pearson Education, Inc. Introduction • The integumentary system is composed of: • Skin • Hair • Nails • Sweat glands • Oil glands • Mammary glands © 2015 Pearson Education, Inc. Introduction • The skin is the most visible organ of the body • Clinicians can tell a lot about the overall health of the body by examining the skin • Skin helps protect from the environment • Skin helps to regulate body temperature © 2015 Pearson Education, Inc. Integumentary Structure and Function • Cutaneous Membrane • Epidermis • Dermis • Accessory Structures • Hair follicles • Exocrine glands • Nails © 2015 Pearson Education, Inc. Figure 4.1 Functional Organization of the Integumentary System Integumentary System FUNCTIONS • Physical protection from • Synthesis and storage • Coordination of immune • Sensory information • Excretion environmental hazards of lipid reserves response to pathogens • Synthesis of vitamin D3 • Thermoregulation and cancers in skin Cutaneous Membrane Accessory Structures Epidermis Dermis Hair Follicles Exocrine Glands Nails • Protects dermis from Papillary Layer Reticular Layer • Produce hairs that • Assist in • Protect and trauma, chemicals protect skull thermoregulation support tips • Nourishes and • Restricts spread of • Controls skin permeability, • Produce hairs that • Excrete wastes of fingers and supports pathogens prevents water loss provide delicate • Lubricate toes epidermis penetrating epidermis • Prevents entry of -
There Are 25 Questions, Each Worth 3 Points and a Short Essay Worth 25 Points. DO YOUR OWN WORK !! Use Your Time Wisely 1. T
Mr. Holder Integumentary System – Unit 5 December 3, 2015 ARC TEST 1.0 DO NOT MARK OR WRITE ON THIS QUIZ !! There are 25 questions, each worth 3 points and a short essay worth 25 points. DO YOUR OWN WORK !! Use Your Time Wisely 1. The Integumentary System is divided into how many layers? a) 2 b) 3 c) 4 d) 6 2. What are the two major groups of membranes covering the human body? a) Epithelial & Mucus b) Cutaneous & Mucus c) Epithelial & Connective Tissue d) None of these 3. Which internal membrane provides protection for your joints? a) Serous b) Synovial c) Cutaneous d) Mucus 4. These membranes line internal cavities exposed to air & excrete a gooey substance. a) Serous b) Synovial c) Cutaneous d) Mucus 5. The Integumentary System protects the human body from … a) Friction b) Hot & Cold Temperature c) Bacteria d) All of These 6. Which stratum of the epidermis is full of keratin, cornified to prevent water loss? a) Basale b) Granulosum c) Corneum d) None of These 7. Which body system extends into the dermis to provide information to your brain? a) Cardiovascular b) Immune c) Integumentary d) Nervous 8. Subcutaneous tissue includes adipose tissue or fat. It is also known as the … a) Dermis b) Papillary Layer c) Hypodermis d) Reticular Layer 9. The dermis is divided into two layers. Which of these is the thickest? a) Papillary b) Reticular c) Basale d) Hypodermis 10. Which stratum of the epidermis is responsible for new cell production? a) Corneum b) Basale c) Granulosum d) Spinosum Page 1 Mr. -
Curling Cuticles of the Great Toenails: a Case Report of Eponychogryphosis
Open Access Case Report DOI: 10.7759/cureus.3959 Curling Cuticles of the Great Toenails: A Case Report of Eponychogryphosis Philip R. Cohen 1 1. Dermatology, San Diego Family Dermatology, San Diego, USA Corresponding author: Philip R. Cohen, [email protected] Abstract The cuticle, also referred to as the eponychium, creates a seal between the proximal nail fold and the nail plate. It is derived from both the ventral and dorsal portions of the proximal nail fold. In addition to its principle function as a barrier preventing allergens, irritants and pathogens from entering the nail cul-de- sac, the cuticle can play a role as a model for evaluating the etiology and management of diseases that affect capillary microcirculation, provide a source of solid tissue for genetic disorder studies, and aid in the evaluation of patients in whom the diagnoses of either systemic scleroderma or dermatomyositis is being entertained. Curling cuticle is a distinctive and unique occurrence. The clinical features of a man with curling cuticles on the lateral portion of both great toes is described. Although a deficiency in personal hygiene may partially account for the clinical finding, the pathogenesis of this observation remains to be established. The term ‘eponychogryphosis’ is proposed to describe the alteration of the patient’s cuticles. Categories: Dermatology, Internal Medicine, Rheumatology Keywords: curl, curling, cuticle, eponychium, eponychogryphosis, fold, great, onychogryphosis, nail, toe Introduction The cuticle, also known as the eponychium, is an extension of the stratum corneum from the proximal nail fold [1-3]. It forms a seal that prevents allergens, irritants, and pathogens from entering the potential space between the distal skin of the digit and the nail plate [4-5]. -
Basic Biology of the Skin 3
© Jones and Bartlett Publishers, LLC. NOT FOR SALE OR DISTRIBUTION CHAPTER Basic Biology of the Skin 3 The skin is often underestimated for its impor- Layers of the skin: tance in health and disease. As a consequence, it’s frequently understudied by chiropractic students 1. Epidermis—the outer most layer of the skin (and perhaps, under-taught by chiropractic that is divided into the following fi ve layers school faculty). It is not our intention to present a from top to bottom. These layers can be mi- comprehensive review of anatomy and physiol- croscopically identifi ed: ogy of the skin, but rather a review of the basic Stratum corneum—also known as the biology of the skin as a prerequisite to the study horny cell layer, consisting mainly of kera- of pathophysiology of skin disease and the study tinocytes (fl at squamous cells) containing of diagnosis and treatment of skin disorders and a protein known as keratin. The thick layer diseases. The following material is presented in prevents water loss and prevents the entry an easy-to-read point format, which, though brief of bacteria. The thickness can vary region- in content, is suffi cient to provide a refresher ally. For example, the stratum corneum of course to mid-level or upper-level chiropractic the hands and feet are thick as they are students and chiropractors. more prone to injury. This layer is continu- Please refer to Figure 3-1, a cross-sectional ously shed but is replaced by new cells from drawing of the skin. This represents a typical the stratum basale (basal cell layer). -
Anatomy and Physiology of the Nail
Anatomy and physiology of the nail Christian Dumontier Institut de la Main & hôpital saint Antoine, Paris Anatomy of the nail • The osteo-ligamentous support • Nail plate • All surrounding tissues, i.e. the perionychium The distal phalanx • Is reinforced laterally by the the Flint’s ligament • Which protect the neuro-vascular structures Flint’s ligament The ligamentous support • The nail is fixed onto the bone through a highly vascularized dermis • The nail is fixed onto the bone through two strong ligaments The ligamentous structures • All the ligaments merge together with • The extensor tendon • The flexor tendon • The collateral ligaments • Flint’s ligament • Guero’s dorsal ligament • (Hyponychial ligament) Clinical implications • A normal nail cannot grow on an abnormal support +++ • Large phalanx = racket nails • bony malunion = nail dystrophy • arthrosis = Pincer nail,... The nail plate • Is produced by the germinal matrix • ItsKeratinic shape depends structure, on the bonypartiall supporty transparent and the and integritycurved both of the longitudinall soft-tissuesy arandound transv it ersally • Three different layers • 0,5 mm thickness, 20% of water Clinical applications • The nail plate is often intact in crushing trauma due to its flexibility • And must be removed in order to explore all the lesions +++ The perionychium • Include all the soft- tissues located under the nail plate • Nail (germinal) matrix, • Nail bed, • Hyponychium The perionychium • Soft-tissues aroud the plate (paronychium) proximal and lateral nail wall (fold) -
The Nail Bed, Part I. the Normal Nail Bed Matrix, Stem Cells, Distal Motion and Anatomy
Central Journal of Dermatology and Clinical Research Review Article *Corresponding author Nardo Zaias, Department of Dermatology Mount Sinai Medical Center, Miami Beach, FL. 33140, 4308 The Nail Bed, Part I. The Normal Alton rd. Suite 750, USA, Email: [email protected] Submitted: 25 November 2013 Nail Bed Matrix, Stem Cells, Distal Accepted: 28 December 2013 Published: 31 December 2013 Copyright Motion and Anatomy © 2014 Zaias Nardo Zaias* OPEN ACCESS Department of Dermatology Mount Sinai Medical Center, USA Abstract The nail bed (NB) has its own matrix that originates from distinctive stem cells. The nail bed matrix stem cells (NBMSC) lie immediately distal to the nail plate (NP) matrix cells and are covered by the keratogenous zone of the most distal NPM (LUNULA). The undivided NBMS cells move distally along the NB basement membrane toward the hyponychium; differentiating and keratinizing at various locations, acting as transit amplifying cells and forming a thin layer of NB corneocytes that contact the overlying onychocytes of the NP, homologous to the inner hair root sheath. At the contact point, the NB corneocytes express CarcinoEmbryonic Antigen (CEA), a glycoprotein-modulating adherence which is also found in hair follicles and tumors. Only when both the NP and the NB are normal do they synchronously move distally. The normal NB keratinizes, expressing keratin K-5 and K-17 without keratohyaline granules. However, during trauma or disease states, it reverts to keratinization with orthokeratosis and expresses K-10, as seen in developmental times. Psoriasis is the only exception. Nail Bed epidermis can express hyperplasia and giant cells in some diseases. -
Hair Structure Cuticle
Structure of Hair Hair Structure Hair is composed of three principal parts: Cuticle – outer coating composed of overlapping scales Cortex – protein-rich structure around Medulla – central core the medulla that contains pigment (may be absent) The structure of hair has been compared to that of a pencil with the medulla being the lead, the cortex being the wood and the cuticle being the paint on the outside. http://library.thinkquest.org/04oct/00206/lesson.htm#t_hair Structure of Hair Hair under the microscope • Basic components: keratin (a protein), melanin (a pigment), and trace quantities of metallic elements (Cu, Fe, Mn,etc). • Elements are deposited in hair during growth and absorbed by the hair from external environment. Hair Structure Cuticle The cuticle varies in: • Its scales, How many there are per centimeter, How much they overlap, Their overall shape, and How much they protrude from the surface • Its thickness, and • Whether or not it contains pigment. Characteristics of the cuticle may be important in distinguishing between hairs of different species but are often not useful in distinguishing between different people. Info: http://library.thinkquest.org/04oct/00206/lesson.htm#t_hair Image: http://www.hairdressersus.com/micro/Image5b.jpg HAIR SHAFT Cuticle – First Layer • The cuticle is a translucent outer layer of the hair shaft consisting of scales that cover the shaft. • The cuticle scales always point AWAY from the root end - toward the tip of the hair. • The cuticle is a GOOD WAY to tell species apart The Cuticle of Human Hair is rough --- which is why we use Conditioner Cuticle under the microscope Cuticle Scales: Coronal • Scales show crown- shaped pattern • Found in small rodents and bats • Coronal pattern is NEVER seen in human hair FREE-TAILED BAT HAIR CUTICLE SCALES: SPINOUS • Spinous - petal-like scales are triangular in shape and protrude from the hair shaft. -
•Nail Structure •Nail Growth •Nail Diseases, Disorders, and Conditions
•Nail Structure Nail Theory •Nail Growth •Nail Diseases, Disorders, and Conditions Onychology The study of nails. Nail Structure 1. Free Edge – Extends past the skin. 2. Nail Body – Visible nail area. 3. Nail Wall – Skin on both sides of nail. 4. Lunula – Whitened half-moon 5. Eponychium – Lies at the base of the nail, live skin. 6. Mantle – Holds root and matrix. Nail Structure 7. Nail Matrix – Generates cells that make the nail. 8. Nail Root – Attached to matrix 9. Cuticle – Overlapping skin around the nail 10. Nail Bed – Skin that nail sits on 11. Nail Grooves – Tracks that nail slides on 12. Perionychium – Skin around nail 13. Hyponychium – Underneath the free edge Hyponychium Nail Body Nail Groove Nail Bed Lunula Eponychium Matrix Nail Root Free Edge Nail Bed Eponychium Matrix Nail Root Nail Growth • Keratin – Glue-like protein that hardens to make the nail. • Rate of Growth – 4 to 6 month to grow new nail – Approx. 1/8” per month • Faster in summer • Toenails grow faster Injuries • Result: shape distortions or discoloration – Nail lost due to trauma. – Nail lost through disease. Types of Nail Implements Nippers Nail Clippers Cuticle Pusher Emery Board or orangewood stick Nail Diseases, Disorders and Conditions • Onychosis – Any nail disease • Etiology – Cause of nail disease, disorder or condition. • Hand and Nail Examination – Check for problems • Six signs of infection – Pain, swelling, redness, local fever, throbbing and pus Symptoms • Coldness – Lack of circulation • Heat – Infection • Dry Texture – Lack of moisture • Redness -
Science of the Nail Apparatus David A.R
1 CHAPTER 1 Science of the Nail Apparatus David A.R. de Berker 1 and Robert Baran 2 1 Bristol Dermatology Centre , Bristol Royal Infi rmary , Bristol , UK 2 Nail Disease Center, Cannes; Gustave Roussy Cancer Institute , Villejuif , France Gross anatomy and terminology, 1 Venous drainage, 19 Physical properties of nails, 35 Embryology, 3 Effects of altered vascular supply, 19 Strength, 35 Morphogenesis, 3 Nail fold vessels, 19 Permeability, 35 Tissue differentiation, 4 Glomus bodies, 20 Radiation penetration, 37 Factors in embryogenesis, 4 Nerve supply, 21 Imaging of the nail apparatus, 37 Regional anatomy, 5 Comparative anatomy and function, 21 Radiology, 37 Histological preparation, 5 The nail and other appendages, 22 Ultrasound, 37 Nail matrix and lunula, 7 Phylogenetic comparisons, 23 Profi lometry, 38 Nail bed and hyponychium, 9 Physiology, 25 Dermoscopy (epiluminescence), 38 Nail folds, 11 Nail production, 25 Photography, 38 Nail plate, 15 Normal nail morphology, 27 Light, 40 Vascular supply, 18 Nail growth, 28 Other techniques, 41 Arterial supply, 18 Nail plate biochemical analysis, 31 Gross anatomy and terminology with the ventral aspect of the proximal nail fold. The intermediate matrix (germinative matrix) is the epithe- Knowledge of nail unit anatomy and terms is important for lial structure starting at the point where the dorsal clinical and scientific work [1]. The nail is an opalescent win- matrix folds back on itself to underlie the proximal nail. dow through to the vascular nail bed. It is held in place by The ventral matrix is synonymous with the nail bed the nail folds, origin at the matrix and attachment to the nail and starts at the border of the lunula, where the inter- bed. -
What's New in Nail Anatomy? the Latest Facts
What’s New in Nail Anatomy? The Latest Facts! by Doug Schoon April 2019: The Internet is filled with confusing and competing misinformation about nail anatomy. I’ve been on a multi-year quest to determine all the facts but finding them has been very difficult. Many doctors and scientists are also confused by the various “schools of thought.” To get to the root of the issue, I’ve worked with many world-class medical experts and internationally known nail educators, in addition to reviewing dozens of scientific reports. I’d like to explain some new information in hopes of ending the confusion. It is agreed that the proximal nail fold (PNF) is the entire flap of skin covering the matrix, extending from the edge of the visible nail plate to the first joint of the finger. However, there is continuing disagreement about the eponychium. I’ve researched all sides of this debate and I hope this information will clear up confusion. Eponychium literally means “upon the nail”. This is the tissue that covers the new growth of nail plate. Why is there so much confusion about the location of the eponychium? Here’s why. Strangely, in some medical literature, another type of tissue is also identified as eponychium, which creates confusion. Of course, it is confusing with two different types of tissue having the same name. The eponychium creates the cuticle and covers the new growth of nail plate, this other tissue does not. To avoid confusion, we should only refer to the eponychium as the underside portion of the proximal nail fold that covers the new growth of nail plate and creates the cuticle. -
Anatomy of Skin Kyle EB
Anatomy of Skin Kyle EB 1.What is wrong with Kyle? 2.How does this condition affect Kyle’s health/life? 3.What is the new treatment? 4.What would you do if you were Kyle? (receive the treatment or not?) The Story of Kyle Hicks http://www.kansas. com/news/local/education/article21264273.html Skin ● The external surface of the body. ● Also referred to as the cutaneous membrane. ● About 16% of an adult’s total body weight. (So if you weigh 100 lbs that means your skin weighs 16 lbs) Structure of the Skin ● Two main parts: ○ Epidermis ■ superficial ■ thinner ■ epithelial tissue ○ Dermis ■ deeper ■ thicker ■ connective tissue *The two layers are attached by the basement membrane. ● Subcutaneous layer (subQ) ○ Also called the hypodermis. ○ Deep to the dermis, but not part of the skin. ○ consists of areolar and adipose ct ○ Attaches skin to underlying tissues and organs. Epidermis ● It is keratinized stratified squamous epithelium ● 4 key cells: 1. Keratinocytes ○ They make the protein keratin (a tough, protective protein). ○ The most numerous cell type: about 90% of the epidermal cells. 2. Melanocytes ○ About 8% of the epidermal cells. ○ Make the protein pigment melanin. ■ contributes to skin color ■ absorbs damaging ultraviolet light. 3. Langerhans cells ○ Immune cells located in the epidermis. 4. Merkel cells ○ associated with touch Layers of the Epidermis ● Most areas of the body have four strata or layers. This is referred to as thin skin. ● In areas of the body exposed to greater friction, like the fingertips, palms and soles of the feet the epidermis has five strata or layers.