50 Years of Data Science
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												  Data Science Initiative 1Data Science Initiative 1 3 credits in data and computational science, 1 credit in societal implications and opportunities, Data Science Initiative 1 elective credit to be drawn from a wide range of focused applications or deeper theoretical exploration, and 1 credit capstone experience. Director We also offer an option as a 5-th Year Master's Program if you are an Sohini Ramachandran undergraduate at Brown. This allows you to substitute maximally 2 credits Direfctor of Graduate Studies with courses you have already taken. Samuel S. Watson Master of Science in Data Science Brown University's Data Science Initiative serves as a campus hub Semester I for research and education in data science. Engaging partners across DATA 1010 Probability, Statistics, and Machine 2 campus and beyond, the DSI 's mission is to facilitate and conduct both Learning domain-driven and fundamental research in data science, increase data DATA 1030 Hands-on Data Science 1 fluency and educate the next generation of data scientists, and ultimately DATA 1050 Data Engineering 1 explore the impact of the data revolution on culture, society, and social justice. We envision our role in the university and beyond as something to Semester II build over time, with the flexibility to meet the changing needs of Brown’s DATA 2020 Statistical Learning 1 students and research community. DATA 2040 Deep Learning and Special Topics in Data 1 The Master’s Program in Data Science (Master of Science, Science ScM) prepares students from a wide range of disciplinary backgrounds DATA 2080 Data and Society 1 for distinctive careers in data science.
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												  Data Science (ML-DL-Ai)Data science (ML-DL-ai) Statistics Multiple Regression Model Building and Evaluation Introduction to Statistics Model post fitting for Inference Types of Statistics Examining Residuals Analytics Methodology and Problem- Regression Assumptions Solving Framework Identifying Influential Observations Populations and samples Detecting Collinearity Parameter and Statistics Uses of variable: Dependent and Categorical Data Analysis Independent variable Describing categorical Data Types of Variable: Continuous and One-way frequency tables categorical variable Association Cross Tabulation Tables Descriptive Statistics Test of Association Probability Theory and Distributions Logistic Regression Model Building Picturing your Data Multiple Logistic Regression and Histogram Interpretation Normal Distribution Skewness, Kurtosis Model Building and scoring for Outlier detection Prediction Introduction to predictive modelling Inferential Statistics Building predictive model Scoring Predictive Model Hypothesis Testing Introduction to Machine Learning and Analytics Analysis of variance (ANOVA) Two sample t-Test Introduction to Machine Learning F-test What is Machine Learning? One-way ANOVA Fundamental of Machine Learning ANOVA hypothesis Key Concepts and an example of ML ANOVA Model Supervised Learning Two-way ANOVA Unsupervised Learning Regression Linear Regression with one variable Exploratory data analysis Model Representation Hypothesis testing for correlation Cost Function Outliers, Types of Relationship,
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												  Data Science: the Big Picture Data Science with R Exploratory Data Analysis with R Data Visualization with R (3-Part)Deep Learning: The Future of AI @MatthewRenze #DevoxxUK Human Cat Dog Car Job Postings for Machine Learning Source: Indeed.com Average Salary by Job Type (USA) $108,000 $101,000 $100,000 Source: Stack Overflow 2017 What is deep learning? What can it do for me? How do I get started? What is deep learning? Deep Learning Deep Learning Artificial intelligence Machine learning Neural network Multiple hidden layers Hierarchical representations Makes predictions with data Deep Learning Artificial intelligence Machine learning Neural network Multiple hidden layers Hierarchical representations Makes predictions with data Artificial Machine Deep Intelligence Learning Learning Artificial Intelligence Explicit programming Explicit programming Encoding domain knowledge Explicit programming Encoding domain knowledge Statistical patterns detection Machine Learning Machine Learning Artificial Machine Statistics Intelligence Learning 푓 푥 푓 푥 Prediction Data Function 푓 푥 Prediction Data Function Cat Dog 푓 푥 Prediction Data Function Cat Dog Is cat? 푓 푥 Prediction Data Function Cat Dog Is cat? Yes Artificial Neuron 푥1 푥2 푦 푥3 inputs neuron outputs Artificial Neuron Σ Artificial Neuron Σ Artificial Neuron 휔1 휔2 휔3 Artificial Neuron 휔0 Artificial Neuron 휔0 휔1 휔2 휔3 Artificial Neuron 푥 1 휔0 휔1 푥2 휑 휔2 Σ 푦 푚 휔3 푥3 푦푘 = 휑  푤푘푗푥푗 푗=0 Artificial Neural Network Artificial Neural Network input hidden output Artificial Neural Network Forward propagation Artificial Neural Network Forward propagation Backward propagation Artificial Neural Network Artificial Neural Network
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												  Supplementary MaterialsTomic et al, SIMON, an automated machine learning system reveals immune signatures of influenza vaccine responses 1 Supplementary Materials: 2 3 Figure S1. Staining profiles and gating scheme of immune cell subsets analyzed using mass 4 cytometry. Representative gating strategy for phenotype analysis of different blood- 5 derived immune cell subsets analyzed using mass cytometry in the sample from one donor 6 acquired before vaccination. In total PBMC from healthy 187 donors were analyzed using 7 same gating scheme. Text above plots indicates parent population, while arrows show 8 gating strategy defining major immune cell subsets (CD4+ T cells, CD8+ T cells, B cells, 9 NK cells, Tregs, NKT cells, etc.). 10 2 11 12 Figure S2. Distribution of high and low responders included in the initial dataset. Distribution 13 of individuals in groups of high (red, n=64) and low (grey, n=123) responders regarding the 14 (A) CMV status, gender and study year. (B) Age distribution between high and low 15 responders. Age is indicated in years. 16 3 17 18 Figure S3. Assays performed across different clinical studies and study years. Data from 5 19 different clinical studies (Study 15, 17, 18, 21 and 29) were included in the analysis. Flow 20 cytometry was performed only in year 2009, in other years phenotype of immune cells was 21 determined by mass cytometry. Luminex (either 51/63-plex) was performed from 2008 to 22 2014. Finally, signaling capacity of immune cells was analyzed by phosphorylation 23 cytometry (PhosphoFlow) on mass cytometer in 2013 and flow cytometer in all other years.
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												  Explainable Deep Learning Models in Medical Image AnalysisJournal of Imaging Review Explainable Deep Learning Models in Medical Image Analysis Amitojdeep Singh 1,2,* , Sourya Sengupta 1,2 and Vasudevan Lakshminarayanan 1,2 1 Theoretical and Experimental Epistemology Laboratory, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada; [email protected] (S.S.); [email protected] (V.L.) 2 Department of Systems Design Engineering, University of Waterloo, Waterloo, ON N2L 3G1, Canada * Correspondence: [email protected] Received: 28 May 2020; Accepted: 17 June 2020; Published: 20 June 2020 Abstract: Deep learning methods have been very effective for a variety of medical diagnostic tasks and have even outperformed human experts on some of those. However, the black-box nature of the algorithms has restricted their clinical use. Recent explainability studies aim to show the features that influence the decision of a model the most. The majority of literature reviews of this area have focused on taxonomy, ethics, and the need for explanations. A review of the current applications of explainable deep learning for different medical imaging tasks is presented here. The various approaches, challenges for clinical deployment, and the areas requiring further research are discussed here from a practical standpoint of a deep learning researcher designing a system for the clinical end-users. Keywords: explainability; explainable AI; XAI; deep learning; medical imaging; diagnosis 1. Introduction Computer-aided diagnostics (CAD) using artificial intelligence (AI) provides a promising way to make the diagnosis process more efficient and available to the masses. Deep learning is the leading artificial intelligence (AI) method for a wide range of tasks including medical imaging problems.
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												  The Split-Apply-Combine Strategy for Data AnalysisJSS Journal of Statistical Software April 2011, Volume 40, Issue 1. http://www.jstatsoft.org/ The Split-Apply-Combine Strategy for Data Analysis Hadley Wickham Rice University Abstract Many data analysis problems involve the application of a split-apply-combine strategy, where you break up a big problem into manageable pieces, operate on each piece inde- pendently and then put all the pieces back together. This insight gives rise to a new R package that allows you to smoothly apply this strategy, without having to worry about the type of structure in which your data is stored. The paper includes two case studies showing how these insights make it easier to work with batting records for veteran baseball players and a large 3d array of spatio-temporal ozone measurements. Keywords: R, apply, split, data analysis. 1. Introduction What do we do when we analyze data? What are common actions and what are common mistakes? Given the importance of this activity in statistics, there is remarkably little research on how data analysis happens. This paper attempts to remedy a very small part of that lack by describing one common data analysis pattern: Split-apply-combine. You see the split-apply- combine strategy whenever you break up a big problem into manageable pieces, operate on each piece independently and then put all the pieces back together. This crops up in all stages of an analysis: During data preparation, when performing group-wise ranking, standardization, or nor- malization, or in general when creating new variables that are most easily calculated on a per-group basis.
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												  Hadley Wickham, the Man Who Revolutionized R Hadley Wickham, the Man Who Revolutionized R · 51,321 Views · More Stats12/15/2017 Hadley Wickham, the Man Who Revolutionized R Hadley Wickham, the Man Who Revolutionized R · 51,321 views · More stats Share https://priceonomics.com/hadley-wickham-the-man-who-revolutionized-r/ 1/10 12/15/2017 Hadley Wickham, the Man Who Revolutionized R “Fundamentally learning about the world through data is really, really cool.” ~ Hadley Wickham, prolific R developer *** If you don’t spend much of your time coding in the open-source statistical programming language R, his name is likely not familiar to you -- but the statistician Hadley Wickham is, in his own words, “nerd famous.” The kind of famous where people at statistics conferences line up for selfies, ask him for autographs, and are generally in awe of him. “It’s utterly utterly bizarre,” he admits. “To be famous for writing R programs? It’s just crazy.” Wickham earned his renown as the preeminent developer of packages for R, a programming language developed for data analysis. Packages are programming tools that simplify the code necessary to complete common tasks such as aggregating and plotting data. He has helped millions of people become more efficient at their jobs -- something for which they are often grateful, and sometimes rapturous. The packages he has developed are used by tech behemoths like Google, Facebook and Twitter, journalism heavyweights like the New York Times and FiveThirtyEight, and government agencies like the Food and Drug Administration (FDA) and Drug Enforcement Administration (DEA). Truly, he is a giant among data nerds. *** Born in Hamilton, New Zealand, statistics is the Wickham family business: His father, Brian Wickham, did his PhD in the statistics heavy discipline of Animal Breeding at Cornell University and his sister has a PhD in Statistics from UC Berkeley.
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												  Reinforcement Learning Data Science Africa 2018 Abuja, Nigeria (12 Nov - 16 Nov 2018)Reinforcement Learning Data Science Africa 2018 Abuja, Nigeria (12 Nov - 16 Nov 2018) Chika Yinka-Banjo, PhD Ayorkor Korsah, PhD University of Lagos Ashesi University Nigeria Ghana Outline • Introduction to Machine learning • Reinforcement learning definitions • Example reinforcement learning problems • The Markov decision process • The optimal policy • Value function & Q-value function • Bellman Equation • Q-learning • Building a simple Q-learning agent (coding) • Recap • Where to go from here? Introduction to Machine learning • Artificial Intelligence (AI) is the study and design of Intelligent agents. • An Intelligent agent can perceive its environment through sensors and it can act on its environment through actuators. • E.g. Agent: Humanoid robot • Environment: Earth? • Sensors: Camera, tactile sensor etc. • Actuators: Motors, grippers etc. • Machine learning is a subfield of Artificial Intelligence Branches of AI Introduction to Machine learning • Machine learning techniques learn from data without being explicitly programmed to do so. • Machine learning models enable the agent to learn from its own experience by extracting useful information from feedback from its environment. • Three types of learning feedback: • Supervised learning • Unsupervised learning • Reinforcement learning Branches of Machine learning Supervised learning • Supervised learning: the machine learning model is trained on many labelled examples of input-output pairs. • Such that when presented with a novel input, the model can estimate accurately what the correct output should be. • Data(x, y): x is input data, y is label Supervised learning task in the form of classification • Goal: learn a function to map x -> y • Examples include; Classification, regression object detection, image captioning etc. Unsupervised learning • Unsupervised learning: here the model extract useful information from unlabeled and unstructured data.
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												  JOHN WILDER TUKEY 16 June 1915 — 26 July 2000Tukey second proof 7/11/03 2:51 pm Page 1 JOHN WILDER TUKEY 16 June 1915 — 26 July 2000 Biogr. Mems Fell. R. Soc. Lond. 49, 000–000 (2003) Tukey second proof 7/11/03 2:51 pm Page 2 Tukey second proof 7/11/03 2:51 pm Page 3 JOHN WILDER TUKEY 16 June 1915 — 26 July 2000 Elected ForMemRS 1991 BY PETER MCCULLAGH FRS University of Chicago, 5734 University Avenue, Chicago, IL 60637, USA John Wilder Tukey was a scientific generalist, a chemist by undergraduate training, a topolo- gist by graduate training, an environmentalist by his work on Federal Government panels, a consultant to US corporations, a data analyst who revolutionized signal processing in the 1960s, and a statistician who initiated grand programmes whose effects on statistical practice are as much cultural as they are specific. He had a prodigious knowledge of the physical sci- ences, legendary calculating skills, an unusually sharp and creative mind, and enormous energy. He invented neologisms at every opportunity, among which the best known are ‘bit’ for binary digit, and ‘software’ by contrast with hardware, both products of his long associa- tion with Bell Telephone Labs. Among his legacies are the fast Fourier transformation, one degree of freedom for non-additivity, statistical allowances for multiple comparisons, various contributions to exploratory data analysis and graphical presentation of data, and the jack- knife as a general method for variance estimation. He popularized spectrum analysis as a way of studying stationary time series, he promoted exploratory data analysis at a time when the subject was not academically respectable, and he initiated a crusade for robust or outlier-resist- ant methods in statistical computation.
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												  Notices: Highlights------------- ----- Tacoma Meeting (June 18-20)-Page 667 Notices of the American Mathematical Society June 1987, Issue 256 Volume 34, Number 4, Pages 601 - 728 Providence, Rhode Island USA ISSN 0002-9920 Calendar of AMS Meetings THIS CALENDAR lists all meetings which have been approved by the Council prior to the date this issue of Notices was sent to the press. The summer and annual meetings are joint meetings of the Mathematical Association of America and the American Mathematical Society. The meeting dates which fall rather far in the future are subject to change; this is particularly true of meetings to which no numbers have yet been assigned. Programs of the meetings will appear in the issues indicated below. First and supplementary announcements of the meetings will have appeared in earlier issues. ABSTRACTS OF PAPERS presented at a meeting of the Society are published in the journal Abstracts of papers presented to the American Mathematical Society in the issue corresponding to that of the Notices which contains the program of the meeting. Abstracts should be submitted on special forms which are available in many departments of mathematics and from the headquarter's office of the Society. Abstracts of papers to be presented at the meeting must be received at the headquarters of the Society in Providence, Rhode Island, on or before the deadline given below for the meeting. Note that the deadline for abstracts for consideration for presentation at special sessions is usually three weeks earlier than that specified below. For additional information. consult the meeting announcements and the list of organizers of special sessions.
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												![R Generation [1] 25](https://docslib.b-cdn.net/cover/5865/r-generation-1-25-805865.webp)  R Generation [1] 25IN DETAIL > y <- 25 > y R generation [1] 25 14 SIGNIFICANCE August 2018 The story of a statistical programming they shared an interest in what Ihaka calls “playing academic fun language that became a subcultural and games” with statistical computing languages. phenomenon. By Nick Thieme Each had questions about programming languages they wanted to answer. In particular, both Ihaka and Gentleman shared a common knowledge of the language called eyond the age of 5, very few people would profess “Scheme”, and both found the language useful in a variety to have a favourite letter. But if you have ever been of ways. Scheme, however, was unwieldy to type and lacked to a statistics or data science conference, you may desired functionality. Again, convenience brought good have seen more than a few grown adults wearing fortune. Each was familiar with another language, called “S”, Bbadges or stickers with the phrase “I love R!”. and S provided the kind of syntax they wanted. With no blend To these proud badge-wearers, R is much more than the of the two languages commercially available, Gentleman eighteenth letter of the modern English alphabet. The R suggested building something themselves. they love is a programming language that provides a robust Around that time, the University of Auckland needed environment for tabulating, analysing and visualising data, one a programming language to use in its undergraduate statistics powered by a community of millions of users collaborating courses as the school’s current tool had reached the end of its in ways large and small to make statistical computing more useful life.
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												  John W. Tukey 1915–2000John W. Tukey 1915–2000 A Biographical Memoir by David R. Brillinger 2018 National Academy of Sciences. Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. JOHN WILDER TUKEY June 16, 1915–July 26, 2000 Elected to the NAS, 1961 John Wilder Tukey was renowned for research and service in academia, industry, and government. He was born June 16, 1915, in New Bedford, Massachusetts, the only child of Adah M. Takerand Ralph H. Tukey. His parents had grad- uated first and second in the Bates College class of 1898. John had unusual talents from an early age. He could read when he was three, and had remarkable powers of mental calculation. His father had obtained a doctorate in Latin from Yale University and then moved on to teach and be principal at New Bedford High School. His mother was a substitute teacher there. Perhaps as a consequence of these backgrounds, Tukey was schooled at home, but he did attend various classes at the high school. By David R. Brillinger Tukey’s wife, Elizabeth Rapp, was born on March 2, 1920, in Ocean City, New Jersey. She went to Temple Univer- sity and was later valedictorian in the 1944 class in business administration at Radcliffe College. About meeting John, she commented that the first time she saw him he was sitting in the front row of a public lecture asking quite difficult questions of the speaker. They later met at a folkdance class that John was teaching.