Medical Instrument Ft)® a Medical Instrument (11) Has a Main Body (12), F I G

Europaisches Patentamt © European Patent Office © Publication number: 0 229 862 Office europeen des brevets A3

© Date of publication of application: © Applicant: TERUMO KABUSHIKI KAISHA 29.07.87 Bulletin 87/31 trading as TERUMO CORPORATION 44-1, 2-chome, Hatagaya Shibuya-Ku © Designated Contracting States: Tokyo 151 (JP) BE DE FR GB SE @ inventor: Takahashi, Akira ® Date of deferred publication of the search report: 6-3, Funakubo 30.09.87 Bulletin 87/40 Fujinomiya-shi Shizuoka-ken(JP) Inventor: Nudeshima, Masahiro 379-1, Nakajima-cho Fujinomiya-shi Shizuoka-ken(JP) Inventor: Sagae, Kyuta 5-2-9, Fujimidai Fuji-shi Shizuoka-ken(JP) Inventor: Hoshino, Hiroshi 1-10-1310, Wakabadai Asahi-ku Yokohama-shi(JP) Inventor: Suzuki, Hiroshi 540 Wasedatsurumaki-cho Shinjuku-ku Tokyo(JP) Inventor: Komakura, Yuko 406-1, Minowa-cho Kohoku-ku Yokohama-shi(JP)

© Medical instrument ft)® A medical instrument (11) has a main body (12), F I G. \ ^on which surface at least one antimicrobial agent is located. The antimicrobial agent is selected from the ^ group consisting of N-(fluorodichloromethylthio)- QQphthalimide, 2-(4-thiazolyl)-benzimidazole, N,N- mdimethyl-N'-phenyl-(N-fluorodichloromethylthio)- ^jsulphamide, 2,4,5,6-tetrachloroisophtharonitrile, para- ^chlorometaxylenol, sodium 2-pyridinethiol-1 -oxide, _zinc 2-pyridinethiol-1 -oxide, and 2,4,4'-trichloro-2'- hydroxyphenyl ether, and suppresses the increase of Q- microorganisms contacting the surface of the main W body (12).

Xerox Copy Centre J) turopean patent Application number EUROPEAN SEARCH REPORT Office EP 86 10 0933

DOCUMENTS CONSIDERED TO BE RELEVANT venation oi uucumem wun indication, wnere appropriate, Relevant CLASSIFICATION OF THE of relevant passages to claim APPLICATION (Int. CI.4)

A US-A-4 302 467 (M. HASEGAWA et al. ) A 61 L 31/00 * Columns 1-3; column 4, line 17; 1-5 A 61 L 29/00 example 5 *

uts-A-4 <>zis ubb (H. GENTH et al.) * Claim 1 *

US-A-3 695 921 (T.H. SHEPHERD) * Claim 8 *

EP-A-0 147 970 (ROHM & HAAS)

EP-A-0 065 884 (UNITIKA)

FR-A-2 022 120 (NATIONAL PATENT) TECHNICAL FIELDS SEARCHED (Int. CI.4) GB-A72 018 270 (TORAY SILICONE) A 61 L DE-A-2 521 451 (SUMITOMO)

CHEMICAL ABSTRACTS, vol. 86, no. 14, April 4, 1977, page 67, ref.no. 910 9 2w; Columbus, Ohio, US & JP-A-76 151 740 (SUMITOMO BAKE- LITE CO., LTD) 27-12-1976.

CHEMICAL ABSTRACTS, vol. 80, no. 14, April 8, 1974, page 32, ref.no. 71527q; Columbus, Ohio, US S JP-A-73. 65 240 (YOSHITOMI PHARM. IND. LTD) 08-09-1973

JS-A-3 911 135 (G. TIRPARK et al.) i in ptsMini ssarcn report nas rjeen drawn up ror an claims jare or completion or tne searcn Examiner rhe Hague 15-07-1987 PELTRE jf\ I CVaUMT Wr UI I fcU UUUUMfcN I S [ : theory or principle underlying the invention z : earlier patent document, but published on, or . ijcuuuuimiy relevant 11 ta*en aiune after the filing date : particularly relevant if combined with another 3 : document cited in the application document of the same category . : document cited for other reasons : technological background i : non-written disclosure I : member of the same patent family, corresponding : intermediate document document S\ European Patent njn office

I I CLAIMS INCURRING FEES

The present European patent application comprised at the time of filing more than ten claims. All claims fees have been paid within the prescribed time limit. The present EtEuropean search report has been Hromndrawn @up in fnrfor ailait claims.r*\airr>»

□ Only part of the claims fees have been paid within the prescribed time limit The present European search report has been drawn up for the first ten claims and for those claims for which claims fees have been paid, namely claims:

[I No claims fees have been paid within the prescribed time limit The present European search report has been drawn up for the first ten claims. — -

LACK OF UNITY OF INVENTION i no searcn Division considers tnat tne present European patent application does not comply with the requirement of unity of invention and relates to several inventions or groups of inventions, namely: Claims 1-5 in part: 1) A medical instrument comprising N-(f luorodichloromethyl- thio ) -phtalimide 2.) A medical instrument comprising. 2-.( 4-thiazolyl) -benzimidazole : ' •' •'" .. . — - — . . — 3) A medical instrument comprising N, N-dimethyl-N ' -phenyl - (N-f luorodichioromethylthio ) -sulphamide 4) A medical instrument comprising 2,4, 5,6-tetrachloroiso- pht aloni tr i le 5) A medical instrument comprising parachloromethaxylenol 6) A medical instrument comprising sodium- or zinc 2-pyridinethiol-1 -oxide 7 ) A medical. -instrument comprising 2-r4r4 1 -trichloro^Z' - hydroxyphenyl ether

All further search fees have been paid within the fixed time limit. The present European search report has been drawn up for all claims.

□ Only part of the further search fees have been paid within the fixed time limit. The present European search report has been drawn up for those parts of the European patent application which relate to the Inventions in respect of which search fees have been paid, namely claims:

| | None of the further search fees has been paid within the fixed timelimit. The present European search report has been drawn up for those parts of the European patent application which relate to-the Invention first ' * - mentioned in the claims, ~r — •• - '. • ; — ..- .. " - - - namely claims: ;: @ "@ -• •" -.• ; - '' turopean Patent Application number EUROPEAN SEARCH REPORT . Office EP 86 10 0933

- 2 - DOCUMENTS CONSIDERED TO BE RELEVANT citation ot document with indication, where appropriate, Relevant CLASSIFICATION OF THE category of relevant passages to claim APPLICATION (Int. CM) FR-A-2 332 765 (VENTRON)

TECHNICAL FIELDS SEARCHED (Int. CI.4)

i ne present searcn report nas oeen drawn up lor all claims nace ui searcn Date ot completion of the search Examiner

L,A I fclaUK Y UI- UI I tU DOCUMENTS T : theory or principle underlying the invention E : earlier patent document, but published on, or X : particularly relevant if taken alone after the filing date Y : particularly relevant if combined with another D : document cited in the application document of the same category L : document cited for other reasons A : technological background 0 : non-written disclosure & : member of the same patent family, corresponding P : intermediate document document